Reference : A rapid synthesis of thieno[2,3-c]pyridine and 2-substituted thieno[2,3-c]pyridines

	Document type :	Scientific journals : Article
	Discipline(s) :	Physical, chemical, mathematical & earth Sciences : Chemistry
	To cite this reference:	http://hdl.handle.net/2268/4010

Title :	A rapid synthesis of thieno[2,3-c]pyridine and 2-substituted thieno[2,3-c]pyridines
Language :	English
Author, co-author :	Graulich, Amaury [Université de Liège - ULg > > Chimie pharmaceutique >]
	Liégeois, Jean-François [Université de Liège - ULg > Département de pharmacie > Chimie pharmaceutique >]
Publication date :	19-Aug-2004
Journal title :	Synthesis
Publisher :	Georg Thieme Verlag Kg
Issue/season :	12
Pages :	1935-1937
Audience :	International
ISSN :	0039-7881
City :	Stuttgart
Keywords :	[en] cyclizations ; electrophilic aromatic substitutions ; heterocycles ; Schiff bases ; thienopyridine
Abstract :	[en] A convenient preparation of thieno[2,3-c]pyridine 3a and of several original 2-substituted-thieno [2,3-c] pyridines 3b-f is achieved by cyclization of the Schiff base resulting from the condensation between a 2-thiophenecarboxaldehyde 1a-f and aminoacetaldehyde dimethyl acetal. This procedure provides especially good yields in the case of 2-halogenated analogues.
Target :	Researchers ; Professionals ; Students
Permalink :	http://hdl.handle.net/2268/4010

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