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Graulich Amaury

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Main Referenced Co-authors
Liégeois, Jean-François  (14)
Seutin, Vincent  (7)
Moreau, Jacqueline  (5)
Lamy, Cédric  (4)
Alleva, Livia  (3)
Main Referenced Keywords
5-HT2A receptors (2); antagonist (2); antipsychotic drugs (2); autoradiography (2); blockers (2);
Main Referenced Unit & Research Centers
CNCM (1)
Main Referenced Disciplines
Pharmacy, pharmacology & toxicology (8)
Chemistry (8)
Biochemistry, biophysics & molecular biology (3)
Neurosciences & behavior (3)
Physics (2)

Publications (total 15)

The most downloaded
5 downloads
Dilly, S., Graulich, A., Farce, A., Seutin, V., Liégeois, J.-F., & Chavatte, P. (December 2005). Identification of a pharmacophore of SKCa channel blockers. Journal of Enzyme Inhibition and Medicinal Chemistry, 20 (6), 517-523. doi:10.1080/14756360500210989 https://hdl.handle.net/2268/40480

The most cited

84 citations (Scopus®)

Waroux, O., Massotte, L., Alleva, L., Graulich, A., Thomas, E., Liégeois, J.-F., Scuvée-Moreau, J., & Seutin, V. (December 2005). SK channels control the firing pattern of midbrain dopaminergic neurons in vivo. European Journal of Neuroscience, 22 (12), 3111-3121. doi:10.1111/j.1460-9568.2005.04484.x https://hdl.handle.net/2268/5137

Graulich, A., Lamy, C., Alleva, L., Dilly, S., Chavatte, P., Wouters, J., Seutin, V., & Liégeois, J.-F. (2008). Bis-tetrahydroisoquinoline derivatives: AG525E1, a new step in the search for non-quaternary non-peptidic small conductance Ca2+-activated K+ channel blockers. Bioorganic and Medicinal Chemistry Letters, 18 (11), 3440-3445. doi:10.1016/j.bmcl.2008.03.069
Peer Reviewed verified by ORBi

Graulich, A., Dilly, S., Farce, A., Scuvée-Moreau, J., Waroux, O., Lamy, C., Chavatte, P., Seutin, V., & Liégeois, J.-F. (18 October 2007). Synthesis and Radioligand Binding Studies of Bis-Isoquinolinium Derivatives as Small Conductance Ca(2+)-Activated K(+) Channel Blockers. Journal of Medicinal Chemistry, 50 (21), 5070-5075. doi:10.1021/jm070412j
Peer Reviewed verified by ORBi

Graulich, A., Norberg, B., Liégeois, J.-F., & Wouters, J. (July 2007). (+/-)-2-Benzoyl-8-ethyl-1,2-dihydro-isoquinoline-1-carbonitrile: an original Reissert compound. Acta Crystallographica. Section E, Structure Reports Online, 63 (Part 7), 3161-U3073. doi:10.1107/S1600536807027729
Peer Reviewed verified by ORBi

Carato, P., Graulich, A., Jensen, N., Roth, B. L., & Liégeois, J.-F. (15 March 2007). Synthesis and in vitro binding studies of substituted piperidine naphthamides. Part I: Influence of the substitution on the basic nitrogen and the position of the amide on the affinity for D-2L, D-4.2, and 5-HT2A receptors. Bioorganic and Medicinal Chemistry Letters, 17 (6), 1565-1569. doi:10.1016/j.bmcl.2006.12.096
Peer Reviewed verified by ORBi

Carato, P., Graulich, A., Jensen, N., Roth, B. L., & Liégeois, J.-F. (15 March 2007). Synthesis and in vitro binding studies of substituted piperidine naphthamides. Part II: Influence of the substitution on the benzyl moiety on the affinity for D-2L, D-4.2, and 5-HT2A receptors. Bioorganic and Medicinal Chemistry Letters, 17 (6), 1570-1574. doi:10.1016/j.bmcl.2006.12.106
Peer Reviewed verified by ORBi

Tarazi, F. I., Moran-Gates, T., Gardner, M. P., Graulich, A., Lamy, C., & Liégeois, J.-F. (2007). Long-term effects of JL 13, a potential atypical antipsychotic, on Ionotropic glutamate receptors. Journal of Molecular Neuroscience, 32 (3), 192-198. doi:10.1007/s12031-007-0034-3
Peer Reviewed verified by ORBi

Graulich, A., Scuvée-Moreau, J., Alleva, L., Lamy, C., Waroux, O., Seutin, V., & Liégeois, J.-F. (30 November 2006). Synthesis and radioligand binding studies of methoxylated 1,2,3,4-tetrahydroisoquinolinium derivatives as ligands of the apamin-sensitive Ca2+- activated K+ channels. Journal of Medicinal Chemistry, 49 (24), 7208-7214. doi:10.1021/jm0607395
Peer Reviewed verified by ORBi

Graulich, A. (2006). Synthèse, séparation chirale et évaluation biologique de tétrahydroisoquinoléines en tant que bloqueurs des canaux SK [Doctoral thesis, Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/315295

Moran-Gates, T., Massari, C., Graulich, A., Liégeois, J.-F., & Tarazi, F. I. (15 August 2006). Long-term effects of JL 13, a potential atypical antipsychotic, on rat dopamine and serotonin receptor subtypes. Journal of Neuroscience Research, 84 (3), 675-682. doi:10.1002/jnr.20972
Peer Reviewed verified by ORBi

Dilly, S., Graulich, A., Farce, A., Seutin, V., Liégeois, J.-F., & Chavatte, P. (December 2005). Identification of a pharmacophore of SKCa channel blockers. Journal of Enzyme Inhibition and Medicinal Chemistry, 20 (6), 517-523. doi:10.1080/14756360500210989
Peer Reviewed verified by ORBi

Waroux, O., Massotte, L., Alleva, L., Graulich, A., Thomas, E., Liégeois, J.-F., Scuvée-Moreau, J., & Seutin, V. (December 2005). SK channels control the firing pattern of midbrain dopaminergic neurons in vivo. European Journal of Neuroscience, 22 (12), 3111-3121. doi:10.1111/j.1460-9568.2005.04484.x
Peer Reviewed verified by ORBi

Graulich, A., Scuvée-Moreau, J., Seutin, V., & Liégeois, J.-F. (28 July 2005). Synthesis and radioligand binding studies of C-5- and C-8-substituted 1-(3,4-dimethoxybenzyl)-2,2-dimethyl-1,2,3,4-tetrahydroisoquinoliniums as SK channel blockers related to N-methyl-laudanosine and N-methyl-noscapine. Journal of Medicinal Chemistry, 48 (15), 4972-4982. doi:10.1021/jm049025p
Peer Reviewed verified by ORBi

Scuvée-Moreau, J., Boland, A., Graulich, A., Van Overmeire, L., D'hoedt, D., Graulich-Lorge, F., Thomas, E., Abras, A., Stocker, M., Liégeois, J.-F., & Seutin, V. (November 2004). Electrophysiological characterization of the SK channel blockers methyl-laudanosine and methyl-noscapine in cell lines and rat brain slices. British Journal of Pharmacology, 143 (6), 753-764. doi:10.1038/sj.bjp.0705979
Peer Reviewed verified by ORBi

Graulich, A., & Liégeois, J.-F. (2004). A rapid synthesis of thieno[2,3-c]pyridine and 2-substituted thieno[2,3-c]pyridines. Synthesis, (12), 1935-1937. doi:10.1055/s-2004-829134
Peer reviewed

Spirlet, M.-R., Graulich, A., & Liégeois, J.-F. (December 2003). 8-Methyl-6-(4-methylpiperazin-1-yl)-11H-pyrido[2,3-b][1,4]benzodiazepine. Acta Crystallographica. Section E, Structure Reports Online, 59 (Part 12), 1990-O1991. doi:10.1107/S1600536803026448
Peer Reviewed verified by ORBi

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