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See detailEffect of High Doses of Oral Risedronate (20 Mg/Day) on Serum Parathyroid Hormone Levels and Urinary Collagen Cross-Link Excretion in Postmenopausal Women with Spinal Osteoporosis
Zegels, Brigitte ULg; Eastell, R.; Russell, R. G. et al

in BONE (2001), 28(1), 108-12

The present study describes the biological effects of risedronate, a pyridinyl bisphosphonate, on bone and assesses the safety and tolerability of risedronate when given at high doses, with or without ... [more ▼]

The present study describes the biological effects of risedronate, a pyridinyl bisphosphonate, on bone and assesses the safety and tolerability of risedronate when given at high doses, with or without calcium, to postmenopausal women with spinal osteoporosis. This single-center descriptive, double-blind, placebo-controlled, randomized, parallel group study included 32 postmenopausal white women with at least one radiographically confirmed vertebral compression fracture. Patients were randomized to one of four different dose regimen groups: (i) R-P, risedronate 20 mg/day for 14 days, followed by placebo for 42 days; (ii) R-CP-P, risedronate 20 mg/day for 14 days, followed by elemental calcium 1000 mg/day and placebo for 14 days, then by placebo for 28 days; (iii) R-CP-R-CP, risedronate 20 mg/day for 7 days, followed by elemental calcium 1000 mg/day and placebo for 21 days, then risedronate 20 mg/day for 7 days, and finally elemental calcium 1000 mg/day and placebo for 21 days; and (iv) P, placebo for 56 days. The biological response was investigated by measuring serum calcium, parathyroid hormone (PTH), and 2 h urinary pyridinoline/creatinine (Pyr/Cr) and deoxypyridinoline/creatinine (DPyr/Cr) ratios at baseline and at days 3, 7, 14, 21, 28, 35, 42, 49, 56, and 84. Overall, there were no consistent trends observed between the active group and placebo for serum calcium. In groups R-P, R-CP-P, and R-CP-R-CP, mean serum PTH levels were elevated above baseline values for the entire 56 day treatment period and remained elevated, although to a lesser extent, at the day 84 follow-up visit. The effect of calcium supplementation on PTH was variable. Urinary Pyr/Cr and DPyr/Cr ratios were decreased from baseline over the entire study period in all groups receiving risedronate. The maximum observed percent decreases from baseline for Pyr/Cr and DPyr/Cr were -46.9% and -58.8%, respectively, at day 49 in the R-CP-R-CP group. In conclusion, risedronate given orally at a dose of 20 mg/day, continuously for 7 or 14 days, resulted in the expected biological response in osteoporotic women. The time course of changes in PTH levels following cessation of dosing was unaffected by calcium supplementation. There was no evidence of a PTH-mediated rebound in bone resorption following cessation of therapy. Furthermore, based on collagen cross-link data, patients did not show an excessive reduction in bone turnover. [less ▲]

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See detailRural development in Wallonia (Belgium) - Academic point of view.
Claustriaux, Jean-Jacques ULg; Lebailly, Philippe ULg

in Sbornik praci z mezinarodni vedecke konference, Agrarni perspektivyVII. Evropska integrace a vyuzivani prirodnich zdroju, Dil I, Praha,Czech Republic, 17.-18. Zari 1998. (1998)

More and more, european universities will be involved in research topics concerning rural development. Common Agricultural Policy is modified and concerns specific area when the support of european funds ... [more ▼]

More and more, european universities will be involved in research topics concerning rural development. Common Agricultural Policy is modified and concerns specific area when the support of european funds will be focus. In Wallonia, we have a large experience of this kind of policy started in 1981 with Integrated Development Program. The main goal of this paper is to present some characteristics of Wallonia and some research topics initiated by Universities. [less ▲]

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See detailL'informatique au service de l'agriculture - Catalogue 1997
Claustriaux, Jean-Jacques ULg; Ramlot, Pierre ULg

Textual, factual or bibliographical database (1997)

Detailed reference viewed: 6 (1 ULg)
See detailL'informatique au service de l'agriculture : catalogue 1986
Claustriaux, Jean-Jacques ULg; Ramlot, Pierre ULg; Lejeune, J. M.

Textual, factual or bibliographical database (1985)

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See detailLe carreau. Analyse textuelle d'un poème de René Char
Tilkin, Françoise ULg

in ∏ , Tijdschrift voor poezie (1984), 2(3), 72-81

Detailed reference viewed: 64 (2 ULg)
See detailNicoletta CHERUBINI, Pierre nue, poème-légende des photographies de Nguyen Van Thong
Tilkin, Françoise ULg

in Catalogue de l'exposition Pierres nues (Liège, du 26 mai au 30 juin 1984) (1984)

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See detailLe thème du double dans l'œuvre d'Emma Santos
Tilkin, Françoise ULg

in Écritures 82-83 (1983)

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See detailFl. ERMINI, "à grand'peine..."
Tilkin, Françoise ULg

in Journal des Poètes (1983), (4-5), 26

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See detailL'antipsychiatre et la plume
Tilkin, Françoise ULg

in Revue belge de philologie et d'histoire (1982), 60(4), 1083-1084

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See detailFroissart et le héraut Chandos
Tilkin, Françoise ULg; Thiry, Claude ULg

in Moyen Age (Le) (1982), 88

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See detailFabio DOPLICHER, Le masque de Faust
Tilkin, Françoise ULg; Cherubini, Nicoletta; Joppolo, Giovanni

Book published by Shakespeare and Company di Giuseppe Recchia (1981)

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See detailUne citation inexacte de Lucain par Charles le Téméraire et Louis XI
Tilkin, Françoise ULg; Thiry, Claude ULg

in Moyen Age (Le) (1980), 86

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Hubert, Eugène ULg

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Merten, Oscar ULg

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Merten, Oscar ULg

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Merten, Oscar ULg

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