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See detailSearching for Plausible N-k Contingencies Endangering Voltage Stability
Weckesser, Johannes ULg; Van Cutsem, Thierry ULg

in IEEE International Conference on Innovative Smart Grid Technologies IEEE ISGT Europe 2017, Turin 26-29 September 2017 (in press)

This paper presents a novel search algorithm using time-domain simulations to identify plausible N-k contingencies endangering voltage stability. Starting from an initial list of disturbances ... [more ▼]

This paper presents a novel search algorithm using time-domain simulations to identify plausible N-k contingencies endangering voltage stability. Starting from an initial list of disturbances, progressively more severe contingencies are investigated. After simulation of a N-k contingency, the simulation results are assessed. If the system response is unstable, a plausible harmful contingency sequence has been found. Otherwise, components affected by the contingencies are considered as candidate next event leading to N-(k+1) contingencies. This implicitly takes into account hidden failures of component protections. The performance of the proposed search algorithm is compared to a brute-force algorithm and demonstrated on the IEEE Nordic test system. [less ▲]

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See detailIn San Carlo all’Arena district: positive and negative values in a degraded cultural landscape
Rapalo, Maria Chiara ULg

in Atti del Convegno Internazionale La Baia di Napoli. Strategie integrate per la conservazione e la fruizione del paesaggio culturale (in press)

Located in the 'inner periphery' of Neapolitan historic center, at the foot of Capodimonte Park, historically the urban fabric of San Carlo Arena district eastern area has developed around two ... [more ▼]

Located in the 'inner periphery' of Neapolitan historic center, at the foot of Capodimonte Park, historically the urban fabric of San Carlo Arena district eastern area has developed around two architectural complexes: Santa Maria dei Miracoli and Santa Maria degli Angeli alle Croci, for a long time aggregation places for local people. In addition, the ‘lava dei Vergini’ phenomenon, which periodically flooded the area outside the ancient city walls and the ‘for a via’ street (Via Foria), created optimal conditions for tuff extraction, used for local construction. In the past, physical features, such as the irregularity of the hilly area modeled by natural agents, the presence of several underground quarries, the grandeur of remarkable architectural presence, the numerous alleys in a heavily layered historical fabric, and the peculiarities of the social life that took place beyond Foria, have been a source of inspiration for several and also internationally renowned artists. The original identity of the ancient outer suburb, born from progressive expansions of the neighboring villages outside the city walls, is still marked. The closing elements that caracterize the architecture - in particular building fronts -, reflect its inhabitants attitudes and daily life. In this historic urban landscape 'shred’, this closure - despite the direct proximity to the adjacent old town and several, but not easily accessible, panoramic views of part of Naples Bay - continues to be one of the main identifying characters of the area. Although, for many centuries, this has allowed the 'spirit of places’ conservation, it has been transformed into a voluntary closure against the legality, which led to today serious state of neglect and social decay. Sometimes it is possible to find an excessive and illegal man-soil interaction, and unlawful activities influence and define some features of historical buildings in the area. However, for some years the local population has become aware of the existing problems by operating in a more concrete way, through different kinds of associations and volunteer that try to face the territory needs and emergencies. The goal is the elaboration of an update overview of the existing dynamics in this part of urban tissue and the identification of elements to take into account for possible enhancement perspectives in respect of an identity between invariant and processing factors. [less ▲]

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See detailLa grammaire du raisonnable. Ethnographie des pratiques interprétatives au Conseil d'Etat belge
Colemans, Julie ULg

in Colemans, Julie; Dupret, Baudouin (Eds.) Ethnographies du raisonnement juridique (in press)

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See detailDons de livres à Louise de Savoie
Fagnart, Laure ULg

in Heering, Caroline (Ed.) Le don mis en scène. Représentations visuelles et textuelles de l’acte de donation dans les arts de la première Modernité (in press)

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See detailPharmacokinetic characterization of [18F]UCB-H PET radiopharmaceutical in the rat brain.
Becker, Guillaume ULg; Warnier, Corentin; Serrano Navacerrada, Maria Elisa ULg et al

in Molecular Pharmaceutics (in press)

The synaptic vesicle glycoprotein 2A (SV2A), a protein essential to the proper nervous system function, is found in presynaptic vesicles. Thus, SV2A targeting, using dedicated radiotracers combined with ... [more ▼]

The synaptic vesicle glycoprotein 2A (SV2A), a protein essential to the proper nervous system function, is found in presynaptic vesicles. Thus, SV2A targeting, using dedicated radiotracers combined with positron emission tomography (PET), allows the assessment of synaptic density in the living brain. The first-in-class fluorinated SV2A specific radioligand, [18F]UCB-H, is now available at high-activity through an efficient radiosynthesis compliant with the current good manufacturing practices (cGMP). We report here a non-invasive method to quantify [18F]UCB-H binding in rat brain with microPET. Validation study in rats confirmed the need of high enantiomeric purity to target SV2A in vivo. We demonstrated the reliability of a population-based input function to quantify SV2A in preclinical microPET setting. Finally, we investigated the in vivo metabolism of [18F]UCB-H and confirmed the negligible amount of radiometabolites in the rat brain. Hence, the in vivo quantification of SV2A using [18F]UCB-H microPET seems a promising tool for the assessment of the synaptic density in the rat brain, and opens the way for longitudinal follow-up in neurodegenerative diseases rodents’ models. [less ▲]

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See detailSepsis prediction in critically ill patients by platelet activation markers on ICU admission: a prospective pilot study
LAYIOS, Nathalie ULg; Delierneux, Céline ULg; Hego, Alexandre ULg et al

in Intensive Care Medicine Experimental (in press)

Background: Platelets have been involved in both surveillance and host defense against severe infection. To date, whether platelet phenotype or other hemostasis components could be associated with ... [more ▼]

Background: Platelets have been involved in both surveillance and host defense against severe infection. To date, whether platelet phenotype or other hemostasis components could be associated with predisposition to sepsis in critical illness remains unknown. The aim of this work was to identify platelet markers that could predict sepsis occurrence in critically ill injured patients. Results: This single-center, prospective, observational, 7-month study was based on a cohort of 99 non-infected adult patients admitted to ICUs for elective cardiac surgery, trauma, acute brain injury and post-operative prolonged ventilation and followed up during ICU stay. Clinical characteristics and severity score (SOFA) were recorded on admission. Platelet activation markers, including fibrinogen binding to platelets, platelet membrane P-selectin expression, plasma soluble CD40L, and platelet-leukocytes aggregates were assayed by flow cytometry at admission and 48h later, and also at the time of sepsis diagnosis (Sepsis-3 criteria) and 7 days later for sepsis patients. Hospitalization data and outcomes were also recorded. Of the 99 patients, 19 developed sepsis after a median time of 5 days. SOFA at admission was higher; their levels of fibrinogen binding to platelets (platelet-Fg) and of D-dimers were significantly increased compared to the other patients. Levels 48h after ICU admission were no longer significant. Platelet-Fg % was an independent predictor of sepsis (P = 0.030). By ROC curve analysis cutoff points for SOFA (AUC=0.85) and Platelet-Fg (AUC=0.75) were 8 and 50%, respectively. The prior risk of sepsis (19%) increased to 50% when SOFA was above 8, to 46% when Platelet-Fg was above 50%, and to 87% when both SOFA and Platelet-Fg were above their cutoff values. By contrast, when the two parameters were below their cutoffs, the risk of sepsis was negligible (3.8%). Patients with sepsis had longer ICU and hospital stays and higher death rate. Conclusion: In addition to SOFA, platelet-bound fibrinogen levels assayed by flow cytometry within 24h of ICU admission help identifying critically ill patients at risk of developing sepsis. [less ▲]

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See detailCrystal Structure and Kinetic Analysis of the Class B3 Di-Zinc Metallo-β-Lactamase LRA-12 from an Alaskan Soil Metagenome
Rodríguez, María Margarita; Herman, Raphaël ULg; Ghiglione, Barbara et al

in PLoS ONE (in press)

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See detailIncreased antimicrobial resistance in a novel CMY-54 AmpC-type enzyme with a GluLeu217-218 insertion in the Ω-loop
Pérez-Llarena, Francisco José; Vázquez-Ucha, Juan Carlos; Kerff, Frédéric ULg et al

in Microbial Drug Resistance : Mechanism, Epidemiology, & Disease (in press)

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See detailKülpe on Conscious Cognitive Attitudes
Dewalque, Arnaud ULg

in Discipline Filosofiche (in press)

This paper offers a reconstruction of Külpe’s theory of cognitive attitudes from the perspective of contemporary debates about cognitive phenomenology. I argue that, like Carl Stumpf at approximately the ... [more ▼]

This paper offers a reconstruction of Külpe’s theory of cognitive attitudes from the perspective of contemporary debates about cognitive phenomenology. I argue that, like Carl Stumpf at approximately the same time, Külpe endorses two major claims about cognitive experiences. First, cognitive experiences are best described in terms of cognitive acts, functions or attitudes. Second, cognitive attitudes are intransitively conscious in the sense that they are experienced by, or phenomenally manifest to, the subject. I call the combination of those two claims the conscious cognitive attitudes theory—or CCA for short. I introduce Külpe’s version of CCA, briefly present some rationales supporting it, and conclude that, on the whole, CCA is worth serious consideration when it comes to describing cognitive experiences. [less ▲]

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See detailDiagram, the machine abstraite of contemporary architecture
Van Rooyen, Xavier ULg

Conference (in press)

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See detailJean Englebert, le structuraliste mégastructurel liégeois
Van Rooyen, Xavier ULg

in Archidoc 02 (in press)

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See detailExperimental and theoretical analysis of shear bolted connections for tubular structures
D'Antimo, Marina ULg; Demonceau, Jean-François ULg; Jaspart, Jean-Pierre ULg et al

in Journal of Constructional Steel Research (in press)

In this paper, numerical and experimental investigations devoted to the evaluation of the bearing resistance of tubular members with gusset plates and through-all long bolts are presented. Unlike lap ... [more ▼]

In this paper, numerical and experimental investigations devoted to the evaluation of the bearing resistance of tubular members with gusset plates and through-all long bolts are presented. Unlike lap shear joints, the analysed connection evidences a reduced confinement of the bearing area associated to the use of long bolts and the presence of a gap in the member, which can lead, consequently, to a reduction of the bearing resistance. In order to investigate the behaviour of shear connections made up of thin and thick SHS (Square Hollow Section) profiles and long bolts, an experimental test campaign including 24 specimens and FE simulations have been conducted. Both experimental and FE results have confirmed the influence of local instability on the hole in bearing resistance of thin profiles and the poor accuracy of the available standards for this particular joint typology. In particular, the performed comparisons have shown that, for thin profiles, EC3 model is likely to overestimate the resistance, while for higher thickness of the SHS conservative predictions are obtained. The present paper presents the conducted experimental and numerical investigations, highlighting at the end the need for a proper formulation able to account for the local instability effect on the bearing resistance. [less ▲]

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See detailX-ray study of bow shocks in runaway stars
De Becker, Michaël ULg; del Valle, M.V.; Romero, G.E. et al

in Monthly Notices of the Royal Astronomical Society (in press)

Massive runaway stars produce bow shocks through the interaction of their winds with the interstellar medium, with the prospect for particle acceleration by the shocks. These objects are consequently ... [more ▼]

Massive runaway stars produce bow shocks through the interaction of their winds with the interstellar medium, with the prospect for particle acceleration by the shocks. These objects are consequently candidates for non-thermal emission. Our aim is to investigate the X-ray emission from these sources. We observed with XMM-Newton a sample of 5 bow shock runaways, which constitutes a significant improvement of the sample of bow shock runaways studied in X-rays so far. A careful analysis of the data did not reveal any X-ray emission related to the bow shocks. However, X-ray emission from the stars is detected, in agreement with the expected thermal emission from stellar winds. On the basis of background measurements we derive conservative upper limits between 0.3 and 10 keV on the bow shocks emission. Using a simple radiation model, these limits together with radio upper limits allow us to constrain some of the main physical quantities involved in the non-thermal emission processes, such as the magnetic field strength and the amount of incident infrared photons. The reasons likely responsible for the non-detection of non-thermal radiation are discussed. Finally, using energy budget arguments, we investigate the detectability of inverse Compton X-rays in a more extended sample of catalogued runaway star bow shocks. From our analysis we conclude that a clear identification of non-thermal X-rays from massive runaway bow shocks requires one order of magnitude (or higher) sensitivity improvement with respect to present observatories. [less ▲]

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See detailA review on early gut maturation and colonization in pigs, including biological and dietary factors affecting gut homeostasis
Everaert, Nadia ULg; Van Cruchten, Steven; Weström, Björn et al

in Animal Feed Science & Technology (in press)

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See detailNear-death experiences: actual considerations.
Charland-Verville, Vanessa ULg; Martial, Charlotte ULg; Cassol, Helena ULg et al

in Schnakers, Caroline; Laureys, Steven (Eds.) Coma and Disorders of Consciousness, Second Edition (in press)

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See detailAn active bacterial community linked to high chl-a concentrations in Antarctic winter-pack ice and evidence for the development of an anaerobic sea-ice bacterial community
Eronen-Rasimus, Eeva; Luhtanen, Anne-Mari; Rintala, Janne-Markus et al

in ISME Journal (The) (in press), 1-11

Antarctic sea-ice bacterial community composition and dynamics in various developmental stages were investigated during the austral winter in 2013. Thick snow cover likely insulated the ice, leading to ... [more ▼]

Antarctic sea-ice bacterial community composition and dynamics in various developmental stages were investigated during the austral winter in 2013. Thick snow cover likely insulated the ice, leading to high (o4 μg l–1) chlorophyll-a (chl-a) concentrations and consequent bacterial production. Typical sea-ice bacterial genera, for example, Octadecabacter, Polaribacter and Glaciecola, often abundant in spring and summer during the sea-ice algal bloom, predominated in the communities. The variability in bacterial community composition in the different ice types was mainly explained by the chl-a concentrations, suggesting that as in spring and summer sea ice, the sea-ice bacteria and algae may also be coupled during the Antarctic winter. Coupling between the bacterial community and sea-ice algae was further supported by significant correlations between bacterial abundance and production with chl-a. In addition, sulphate-reducing bacteria (for example, Desulforhopalus) together with odour of H2S were observed in thick, apparently anoxic ice, suggesting that the development of the anaerobic bacterial community may occur in sea ice under suitable conditions. In all, the results show that bacterial community in Antarctic sea ice can stay active throughout the winter period and thus possible future warming of sea ice and consequent increase in bacterial production may lead to changes in bacteria-mediated processes in the Antarctic sea-ice zone. [less ▲]

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See detailTo what extent is Immediate Constituency Analysis dependency-based? A survey of foundational texts
Mazziotta, Nicolas ULg; Kahane, Sylvain

in Proceedings of Depling 2017 (in press)

This paper investigates the seminal texts on Immediate Constituent Analysis and the associated diagrams. We show that the relations between the whole and its parts, that are typical of current phrase ... [more ▼]

This paper investigates the seminal texts on Immediate Constituent Analysis and the associated diagrams. We show that the relations between the whole and its parts, that are typical of current phrase structure trees, were less prominent in the early diagramming efforts than the relationships between units of the same level. This can be observed until the beginning of the 1960’s, including in Chomsky’s Syntactic Structures (1957). We discuss whether such analyses could be said “dependency-based”, according to an attempt to define this term. this term. [less ▲]

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See detailFlow field in shallow reservoir with varying inlet and outlet position
Ferrara, Velia; Erpicum, Sébastien ULg; Archambeau, Pierre ULg et al

in Journal of Hydraulic Research (in press)

Shallow reservoirs are used for multiple purposes, such as storm water retention and trapping of sediments. Reliable predictions of the flow fields are necessary to inform the design and operation of ... [more ▼]

Shallow reservoirs are used for multiple purposes, such as storm water retention and trapping of sediments. Reliable predictions of the flow fields are necessary to inform the design and operation of these structures. Using numerical simulations, we performed a systematic analysis of the influence of the location of the inlet and outlet on the flow fields developing in rectangular shallow reservoirs of various sizes. Depending on the relative location of the inlet and outlet with respect to the reservoir centreline, contrasting flow patterns are obtained, involving either no flow reattachment, or a jet reattached on either of the reservoir sidewalls. The results reveal also the occurrence of bi-stable flow configurations, i.e. different steady state flow fields are reached depending on the flow history. This is of high relevance for the design of shallow reservoirs as such configurations should certainly be avoided to achieve a robust hydraulic sizing of the reservoir. [less ▲]

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See detailCritical review of surface-enhanced Raman spectroscopy applications in the pharmaceutical field
Cailletaud, Johan ULg; De Bleye, Charlotte ULg; Dumont, Elodie ULg et al

in Journal of Pharmaceutical & Biomedical Analysis (in press)

Surface-enhanced Raman spectroscopy (SERS) is a sensitive analytical tool used in the pharmaceutical field in recent years. SERS keeps all the advantages of classical Raman spectroscopy while being is ... [more ▼]

Surface-enhanced Raman spectroscopy (SERS) is a sensitive analytical tool used in the pharmaceutical field in recent years. SERS keeps all the advantages of classical Raman spectroscopy while being is more sensitive allowing its use for the detection and the quantification of low-dose substances contained in pharmaceutical samples. However, the analytical performance of SERS is limited due to the difficulty to implement a quantitative methodology correctly validated. Nevertheless, some studies reported the development of SERS quantitative methods especially in pharmaceutical approaches. In this context, this review presents the main concepts of the SERS technique. The different steps that need to be applied to develop a SERS quantitative method are also deeply described. The last part of the present manuscript gives a critical overview of the different SERS pharmaceutical applications that were developed for a non-exhaustive list of pharmaceutical compounds with the aim to highlights the validation criteria for each application. [less ▲]

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See detailThe social and political background of MPs of immigrant origin: are they any different?
Dodeigne, Jérémy ULg; Vintila, Daniela; Morales, Laura

in Morales, Laura; Saalfeld (Eds.) Pathways to Power: The Political Representation of Citizens of Immigrant Origin in Seven European Democracies (in press)

Detailed reference viewed: 17 (1 ULg)