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See detailSynergistic observations of the giant planets with HST and JWST: Jupiter's auroral emissions
Grodent, Denis ULg

Conference (2017, March 20)

The James Webb Space Telescope is perfectly suited to observe most Solar System objects, including the extended giant planets. Its high sensitivity, high spatial resolution, field of view, very high ... [more ▼]

The James Webb Space Telescope is perfectly suited to observe most Solar System objects, including the extended giant planets. Its high sensitivity, high spatial resolution, field of view, very high spectral resolution and wide spectral coverage all combine to make JWST a fantastic instrument that will result in significant advances and progress in most fields of Solar System exploration. Here, we focus on the case of Jupiter’s aurora for several reasons. 1) The auroral emissions on Jupiter are very intense, both in ultraviolet and in infrared. Each of these bandpasses is bringing complementary information on how Jupiter is interacting with its near and distant environment. 2) Even though Jupiter’s aurora appears to be responding to the conditions prevailing in the solar wind, contrary to the Earth it is a permanent emission that can also be observed on the sunlit side of the planet. 3) The NASA Juno mission is currently exploring the magnetosphere and the atmosphere of this planet with a suite of in situ and remote instruments, including an ultraviolet spectrograph (UVS) and an infrared imaging spectrograph (JIRAM). The Juno mission is gathering a broad scientific community that will foster the study of Jupiter’s system for several years. 4) A large HST program was allocated in support of the NASA Juno prime mission (GO-14634) and is currently providing us with regular movies of Jupiter’s ultraviolet aurora. They provide a global magnetospheric context for the different Juno instruments, as well as for the numerous ground based (infrared) and space based observatories participating to the Juno mission. 5) It is currently very difficult to plan truly simultaneous UV and IR observations, mainly because of the inherent limitations of Earth based infrared telescopes. As a result, comparisons of Jupiter’s auroral emissions rest on a very limited dataset. Nevertheless, they are suggesting similarities and discrepancies between IR and UV aurorae, the study of which would greatly benefit from synergistic observations with HST and JWST. 6) The case of Saturn’s aurora is as important, especially in view of the upcoming ‘Grand Finale’ of the Cassini mission, and all above arguments apply to Saturn as well. The case of Uranus and Neptune’s aurorae still belongs to the area of discovery and will take full advantage of JWST’s advanced capabilities. [less ▲]

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See detailMulti-instrument overview of the 1-hour pulsations in Saturn's magnetosphere
Palmaerts, Benjamin ULg; Roussos, Elias; Radioti, Aikaterini ULg et al

Conference (2017, March 16)

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See detailAdministration of Third-Party Mesenchymal Stromal Cells at the Time of Kidney Transplantation: Interim Safety Analysis at One-Year Follow-Up
WEEKERS, Laurent ULg; ERPICUM, Pauline ULg; DETRY, Olivier ULg et al

Conference (2017, March 16)

Mesenchymal stromal cells (MSC)-based therapy has been proposed in kidney transplantation (KTx). We report on the 1-year follow-up of an open-label phase I trial using MSC in KTx. On postoperative day 3 ... [more ▼]

Mesenchymal stromal cells (MSC)-based therapy has been proposed in kidney transplantation (KTx). We report on the 1-year follow-up of an open-label phase I trial using MSC in KTx. On postoperative day 3, third-party MSC (~2.0x106/kg) were administered to 7 non-immunized first-transplant recip- ients from deceased donors, under standard immunosuppression (Basiliximab, Tacrolimus, MMF and steroids). No HLA matching was required for MSC donors. Seven comparable KTx recipients were included as controls. Informed consent was obtained. No side-effect was noted at the time of MSC injection. Still, 1 patient with a history of ischemic heart disease had a NSTEMI ~3h after MSC infusion. Ten months after KTx, 1 MSC patient had type B aortic dissection and STEMI. Four MSC patients had at least 1 opportunistic infection, whereas 3 controls had polyoma-BK viremia. At day 14, eGFR in MSC and control groups was 47.1 ± 6.8 and 39.7 ± 5.9 ml/min, respectively (p, 0.05). At 1 year, eGFR in MSC and control groups was 46.5 ± 18.6 and 54.2 ± 16.3 ml/min, respectively (p, 0.42). Per-cause biopsies evidenced 1 bor- derline and 1 acute rejections in MSC group, whereas no AR was biopsy-proven in controls. Three patients developed anti-HLA antibodies against MSC (n=1) or shared kidney/MSC (n=2) mismatches.MSC infusion was safe in all patients except one. Incidence of opportunist infections was similar in both groups. No difference in eGFR was found at 1-year post KTx. Putative immunization against MSC was observed in 3 patients. [less ▲]

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See detailintravenous administration of mesenchymal stream cells modulates renal lipid metabolism in rats
ERPICUM, Pauline ULg; Rowart, Pascal ULg; POMA, Laurence ULg et al

Conference (2017, March 16)

Mesenchymal stromal cells (MSC) have been shown to attenuate renal ischemia/reperfusion (I/R) injury in rodents. Still, the mechanisms of such a nephroprotection remain unclear. Here, rats were ... [more ▼]

Mesenchymal stromal cells (MSC) have been shown to attenuate renal ischemia/reperfusion (I/R) injury in rodents. Still, the mechanisms of such a nephroprotection remain unclear. Here, rats were intravenously infused with MSC (1.5x10^6 cells in 1 ml saline; MSCD-7 group, n=6) or equivalent volume of saline (SD-7 group, n=6) 7 days before kidney sampling. High-throughput RNA sequencing technology was used to compare transcriptomic renal profiles, using TopHat and Cufflinks open-source software tools. A total of 494 and 256 genes were found to be significantly (q-value <.05) down- and up-regulated in mscd-7 versus sd-7 groups, respectively. Hierarchical cluster analysis by “david” “webgestalt” softwares highlighted that the metabolic pathways mostly affected msc included adipogenesis, insulin signalling, fatty acid (fa) biosynthesis, il-6 b-cell receptor il-3 pathway nuclear receptors involved lipid me- tabolism. Real-time qpcr immunoblotting analyses confirmed pivotal enzymes of fa biosynthesis were significantly downregulated group, whereas expression ppar alpha, a transcription factor oxidation, was induced msc. Additional- ly, fat />CD36 – a key regulator of membrane uptake of FA – was increased in MSCD-7 kidneys, with a preferential localization in proximal tubules (PT). As a whole, our data suggest that MSC infusion causes critical modifications of lipid metabolism, including (i) down-regulation of FA biosynthesis; (ii) activation of PPAR alpha pathway, and (iii) prioritization of FA as sources of energy in PT cells, which may eventually prevent lipid peroxidation and attenuate renal I/R damage. [less ▲]

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See detailImprinting superconducting vortex footsteps in a magnetic layer
Brisbois, Jérémy ULg

Conference (2017, March 14)

We experimentally show that the principle of local polarization of a magnetic layer, a well-known method to store information, namely in hard drives and credit cards, can be applied for imprinting into a ... [more ▼]

We experimentally show that the principle of local polarization of a magnetic layer, a well-known method to store information, namely in hard drives and credit cards, can be applied for imprinting into a soft magnetic layer of permalloy (Py) the trajectory of vortices moving in a superconducting film (Nb). In full analogy with a magnetic drawing board, vortices act as tiny magnetic scribers leaving a wake of polarized magnetic media in the Py layer. We have used the magneto-optical imaging technique to investigate the mutual interaction between superconducting vortices and ferromagnetic domains. In general, we observe that the flux propagation is delayed at the border of the magnetic layer. Interestingly, in thin Py layers without stripe domains, vortices leave clear imprints of locally polarized magnetic moments along their trajectories. Furthermore, the printings were found to be stable and could still be observed at room temperature, allowing for ex situ observation of the flux penetration in superconductors. We expect our findings to pave the way for further studies for optimizing magnetic recording of superconducting vortex trajectories. [less ▲]

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See detailRealization of the Najafi-Golestanian microswimmer
Hubert, Maxime ULg; Grosjean, Galien ULg; Lagubeau, Guillaume et al

Conference (2017, March 14)

The development of artificial microswimmers, microscopic robots that swim in a fluid like sperm cells and motile bacteria, could cause a leap forward in various fields such as microfluidics, microsystems ... [more ▼]

The development of artificial microswimmers, microscopic robots that swim in a fluid like sperm cells and motile bacteria, could cause a leap forward in various fields such as microfluidics, microsystems, or minimally invasive medicine. Nature provides plenty of examples of efficient microswimmers. However, a bottom-up approach, looking at the simplest ingredients needed to generate a microswimmer, can lead to a deeper under- standing of the swimming problem. First described by Najafi and Golestanian 1 , a paradigmatic microswimmer is the three-linked-spheres model, which follows a minimalist approach for propulsion by shape shifting. In this presentation, we describe the experimental realisation of this microswimmer using self-assembled ferromagnetic particle at an air-water interface, powered by an uniform oscillating magnetic field 2 . A model, using two har- monic oscillators, reproduces the experimental findings. Because the model remains general, the same approach could be used to design a variety of efficient microswimmers. [less ▲]

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See detailMechanisms of Igf2 inhibition in thymic epithelial cells infected with CVB4 E2
Michaux, Hélène ULg; Charlet-Renard, Chantal; Martens, Henri ULg et al

Poster (2017, March 12)

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See detailUnravelling Potential Roles of HTLV-1 Tax and HBZ Proteins in mRNA Splicing Regulation
Vandermeulen, Charlotte ULg; Cherkaoui, Majid ULg; A. Calderwood, Michael et al

Poster (2017, March 08)

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See detailMusical(ized) Biographies: Jackie Kay’s Trumpet and Caryl Phillips’s Dancing in the Dark
Mascoli, Giulia ULg

Conference (2017, March 03)

My paper deals with two musical(ized) biographies: Jackie Kay’s Trumpet (1998) and Caryl Phillips’s Dancing in the Dark (2005). These literary works share features, at once thematic, since the protagonist ... [more ▼]

My paper deals with two musical(ized) biographies: Jackie Kay’s Trumpet (1998) and Caryl Phillips’s Dancing in the Dark (2005). These literary works share features, at once thematic, since the protagonist is a musical performer, and formal, as both writers’ prose is drenched with musicality. The two narratives can thus be considered what Emily Petermann (2014) calls “musical novels”, as both display sonic and structural patterns as well as elements of improvisation (the imitation of orality; the use of different narrators and the inclusion of various types of texts such as lyrics, interviews, excerpts from newspapers, and the solo performances through improvised jazzy breaks and the repetition of the same lexical item). In my paper, I will take my cue from Eric Prieto, who writes that interart analogies should not be taken as ends in themselves, and I will try to show the purpose of such intermediality and how it can contribute to the biographical genre. Among other things, I will examine whether these musicalized biographies have, through their unusual forms, particular social and political relevance and how approaching them from this methodological angle can serve as interpretative aid. [less ▲]

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See detailSemper Incertus: Authorization through Uncertainty in Hanif Kureishi’s My Ear at His Heart: Reading my Father
Munos, Delphine ULg

Conference (2017, March 02)

In Postcolonial Writers in the Global Literary Marketplace (2007), Sarah Brouillette discusses “the centrality of questions of biography in reception of postcolonial texts” (173). She argues that, as ... [more ▼]

In Postcolonial Writers in the Global Literary Marketplace (2007), Sarah Brouillette discusses “the centrality of questions of biography in reception of postcolonial texts” (173). She argues that, as against “the supposed dominant orthodoxy of anti-authorialism in literary studies” (173), successful marketing of postcolonial literature depends on – indeed requires – “biographical authenticity” so that postcolonial writers can figure valid interpreters of an authenticated location for an Anglo-American audience “schooled in multiculturalism.” Brouillette’s perception that the marketing of postcolonial writing depends on the coincidence between literary material and the biographical self of its author raises fascinating questions when it comes to examining ‘postcolonial’ biographies and autobiographies already relying on a “referential pact” (cf. Lejeune) because of their generic anatomy. Biographical fiction, then is a postcolonial nightmare come true, as the specificities of the genre endlessly displace the demand for “biographical authenticity” that is seen by Brouillette to condition the niche marketing of postcolonial literature. This paper looks at Hanif Kureishi’s My Ear at His Heart: Reading My Father (2004), in which the popular British Asian author narrativizes his ambivalent relationship with his father and retraces his father’s life from British India to the UK of the 1960s and 1970s. What is interesting is that Kureishi both relies on memory and on two unpublished ‘fictional’ texts by his late father to reconstruct the latter’s life, thus “imagining around [others’] imagination” (2004: 238), as he phrases it, that is, embracing fiction – not only memory – as a valid starting point for representing the life of his father. Susie Thomas writes that “It is a major irony that Kureishi, as a reader, approaches his father’s novels in a way that he would doubtless object to if his own fiction were raided for its autobiographical content” (2006: 189). My claim is that this “major irony” becomes a means, for Kureishi, of authorizing himself a place outside the ‘British Asian ghetto’ by playing up to the expectations of postcolonial niche marketing. [less ▲]

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See detailThe Future Prevalence of Sarcopenia in Europe: A Claim for Public Health Action.
Ethgen, Olivier ULg; Beaudart, Charlotte ULg; Buckinx, Fanny ULg et al

in Calcified Tissue International (2017), 100(3), 229-234

Sarcopenia is a major public health issue. To convince health policy makers of the emergency to invest in the sarcopenia field, it is of critical importance to produce reliable figures of the expected ... [more ▼]

Sarcopenia is a major public health issue. To convince health policy makers of the emergency to invest in the sarcopenia field, it is of critical importance to produce reliable figures of the expected burden of sarcopenia in the coming years. Age- and gender-specific population projections were retrieved until 2045 from the Eurostat online database (28 European countries). Age- and gender-specific prevalences of sarcopenia were interpolated from a study that compared prevalence estimates according to the different diagnostic cutoffs of the EWGSOP proposed definition. The reported prevalence estimates were interpolated between 65 and 100 years. Interpolated age- and gender-specific estimates of sarcopenia prevalence were then applied to population projections until 2045. Using the definition providing the lowest prevalence estimates, the number of individuals with sarcopenia would rise in Europe from 10,869,527 in 2016 to 18,735,173 in 2045 (a 72.4% increase). This corresponds to an overall prevalence of sarcopenia in the elderly rising from 11.1% in 2016 to 12.9% in 2045. With the definition providing the highest prevalence estimates, the number of individuals with sarcopenia would rise from 19,740,527 in 2016 to 32,338,990 in 2045 (a 63.8% increase), corresponding to overall prevalence rates in the elderly of 20.2% and 22.3% for 2016 and 2045, respectively. We showed that the number of sarcopenic patients will dramatically increase in the next 30 years, making consequences of muscle wasting a major public health issue. [less ▲]

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See detailMassivement histologique : entre continuité et (r)évolution pédagogique. Lancement du premier Massive Open Online Course (MOOC) sur des travaux pratiques en Histologie à destination de nos étudiants mais aussi du grand public.
Multon, Sylvie ULg; Pesesse, Laurence ULg; Weatherspoon, Alodie ULg et al

Poster (2017, March)

L’acronyme anglophone MOOC désigne les « Massive Open Online Courses » que l’on pourrait traduire par « formation en ligne massive ouverte à tous ». Nés aux États-Unis avec un programme sur l’intelligence ... [more ▼]

L’acronyme anglophone MOOC désigne les « Massive Open Online Courses » que l’on pourrait traduire par « formation en ligne massive ouverte à tous ». Nés aux États-Unis avec un programme sur l’intelligence artificielle dispensé par l’université de Stanford, ces cours en ligne accessibles gratuitement font miroiter la possibilité d’une démocratisation maximale des savoirs. A ce titre, les MOOC bénéficient des innovations issues du Web 2.0 : ils tirent le meilleur de la rencontre entre les nouveaux usages induits par les réseaux sociaux et les apports de la pédagogique active. Ces cinq dernières années, nous avons dispensé les travaux pratiques en Histologie aux premières années d’étude de la faculté de Médecine de l’Université de Liège par une méthodologie hybride alliant les bénéfices d’un enseignement à distance et ceux de séances menées en face-à-face (Multon et al., 2015). Notre dispositif d’auto-apprentissage invite chaque année plus de 500 étudiants à parcourir plusieurs coupes d’organes digitalisées afin de découvrir les structures histologiques pointées par des balises interactives pour chaque grande famille de tissus. La mise en ligne d’un MOOC dédié aux travaux pratiques d’Histologie s’inscrit dans une suite logique de nos activités avec une volonté de donner accès à nos ressources numériques à un public plus large. « Découvrir les tissus fondamentaux du corps humain en explorant par vous même des lames histologiques au microscope », tel est le programme de notre MOOC intitulé « Introduction à l’histologie, exploration des tissus du corps humain ». Celui-ci a débuté en février 2017 et est hébergé sur la plate-forme FUN encadrée par le ministère de l’Enseignement supérieur et de la Recherche du ministère français (https://www.fun-mooc.fr/courses/ulg/108001/session01/about). Ce MOOC s’adresse à un public large : aux étudiants ou futurs étudiants dans le domaine médical, paramédical ou scientifique, aux enseignants, chercheurs, professionnels dans le secteur de la santé, décideurs dans le domaine de l’éducation ou de la santé ou simplement aux curieux désireux de comprendre à partir de quoi le corps humain est construit. Deux parcours pédagogiques permettant d’approfondir différemment la matière sont proposés pour correspondre au mieux aux objectifs ou motivations de chacun. Au travers de vidéos explicatives contenant des dessins réalisés sous vos yeux et des liens avec l’anatomie suivie d’activités interactives telles que la manipulation d’un microscope virtuel, de nombreux quiz et d’activités réalisées avec les pairs, les participants seront capables de reconnaître les différents types de cellules et tous les éléments qui les entourent afin de comprendre comment ils s’organisent entre eux pour former des tissus aux fonctions spécifiques. Une recherche est actuellement en cours sur l’étude des traces d’activités des participants au MOOC en fonction du parcours pédagogique choisi afin d’évaluer notamment l’impact des différentes composantes de l’expérience d’apprentissage. [less ▲]

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See detailEnglish translation and validation of the SarQoL®, a quality of life questionnaire specific for sarcopenia
Beaudart, Charlotte ULg; Edwards, Mark; Moss, Charlotte et al

in Age & Ageing (2017), 46(2), 271-7

Background: the first quality of life questionnaire specific to sarcopenia, the SarQoL®, has recently been developed and validated in French. To extend the availability and utilisation of this ... [more ▼]

Background: the first quality of life questionnaire specific to sarcopenia, the SarQoL®, has recently been developed and validated in French. To extend the availability and utilisation of this questionnaire, its translation and validation in other languages is necessary. Objective: the purpose of this study was therefore to translate the SarQoL® into English and validate the psychometric properties of this new version. Design: cross-sectional. Setting: Hertfordshire, UK. Subjects: in total, 404 participants of the Hertfordshire Cohort Study, UK. Methods: the translation part was articulated in five stages: (i) two initial translations from French to English; (ii) synthesis of the two translations; (iii) backward translations; (iv) expert committee to compare the backward translations with the original questionnaire and (v) pre-test. To validate the English SarQoL®, we assessed its validity (discriminative power, construct validity), reliability (internal consistency, test–retest reliability) and floor/ceiling effects. Results: the SarQoL® questionnaire was translated without any major difficulties. Results indicated a good discriminative power (lower score of quality of life for sarcopenic subjects, P = 0.01), high internal consistency (Cronbach’s alpha of 0.88), consistent construct validity (high correlations found with domains related to mobility, usual activities, vitality, physical function and low correlations with domains related to anxiety, self-care, mental health and social problems) and excellent test–retest reliability (intraclass coefficient correlation of 0.95, 95%CI 0.92–0.97). Moreover, no floor/ceiling has been found. Conclusions: a valid SarQoL® English questionnaire is now available and can be used with confidence to better assess the disease burden associated with sarcopenia. It could also be used as a treatment outcome indicator in research. [less ▲]

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See detailOsteoporosis in Frail Patients: A Consensus Paper of the Belgian Bone Club.
Gielen, E.; Bergmann, P.; Bruyère, Olivier ULg et al

in Calcified Tissue International (2017)

In this consensus paper, the Belgian Bone Club aims to provide a state of the art on the epidemiology, diagnosis, and management of osteoporosis in frail individuals, including patients with anorexia ... [more ▼]

In this consensus paper, the Belgian Bone Club aims to provide a state of the art on the epidemiology, diagnosis, and management of osteoporosis in frail individuals, including patients with anorexia nervosa, patients on dialysis, cancer patients, persons with sarcopenia, and the oldest old. All these conditions may indeed induce bone loss that is superimposed on physiological bone loss and often remains under-recognized and under-treated. This is of particular concern because of the major burden of osteoporotic fractures in terms of morbidity, mortality, and economic cost. Therefore, there is an urgent need to appreciate bone loss associated with these conditions, as this may improve diagnosis and management of bone loss and fracture risk in clinical practice. [less ▲]

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See detailMultidisciplinary rehabilitation program after breast cancer: benefits on physical function, anthropometry and quality of life.
Leclerc, Anne-France ULg; Foidart-Dessalle, Marguerite ULg; Tomasella, Marco ULg et al

in European Journal of Physical and Rehabilitation Medicine (2017)

BACKGROUND: Different clinical trials show beneficial effects of physical training offered during and / or after breast cancer treatment. However, given the variety of side effects that may be encountered ... [more ▼]

BACKGROUND: Different clinical trials show beneficial effects of physical training offered during and / or after breast cancer treatment. However, given the variety of side effects that may be encountered, physical training could be combined with psychological, relational and social guidance. This kind of multidisciplinary program has been little studied so far. AIM: To determine the benefits of a three-month multidisciplinary rehabilitation program among women after breast cancer treatment. DESIGN: Controlled no-randomized trial. SETTING: University for outcomes, University Hospital Center for interventions. POPULATION: Two hundred and nine outpatients who have been treated for a primary breast carcinoma. METHODS: Patients were divided into a control group (n=106) and an experimental group (n=103) which has benefited from a rehabilitation program of three months including physical training and psycho-educational sessions. The assessments, performed before and after the program, included functional assessments ("Sit and Reach Test", maximal incremental exercise test and "Six-Minute Walk Test"), body composition measurements (body mass index (BMI) and body fat percentage) and a questionnaire (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30). RESULTS: After three months, flexibility, walking distance and all parameters measured during the maximal incremental exercise, except maximal heart rate, were significantly improved in the experimental group. The body fat percentage was significantly decreased and a significant improvement was observed for perceived health status (quality of life), functional role, emotional state, physical, cognitive and social functions and for most symptoms. In the control group, most of these improvements didn't appear and a significant increase in BMI and body fat percentage was observed. CONCLUSIONS: This trial identifies the benefits of a well detailed multidisciplinary rehabilitation program, including physical re-conditioning and psycho-educational sessions, with important improvements in functional capacity, body composition and the majority of functions and symptoms among women after breast cancer treatment. CLINICAL REHABILITATION IMPACT: Through its results, this study could contribute to the development of hospital quality standards for oncologic rehabilitation. Physiotherapists can efficiently propose this kind of multidisciplinary rehabilitation program. [less ▲]

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See detailNutrition and physical activity in the prevention and treatment of sarcopenia: systematic review.
Beaudart, Charlotte ULg; Dawson, A.; Shaw, S. C. et al

in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2017)

This systematic review summarizes the effect of combined exercise and nutrition intervention on muscle mass and muscle function. A total of 37 RCTs were identified. Results indicate that physical exercise ... [more ▼]

This systematic review summarizes the effect of combined exercise and nutrition intervention on muscle mass and muscle function. A total of 37 RCTs were identified. Results indicate that physical exercise has a positive impact on muscle mass and muscle function in subjects aged 65 years and older. However, any interactive effect of dietary supplementation appears to be limited. INTRODUCTION: In 2013, Denison et al. conducted a systematic review including 17 randomized controlled trials (RCTs) to explore the effect of combined exercise and nutrition intervention to improve muscle mass, muscle strength, or physical performance in older people. They concluded that further studies were needed to provide evidence upon which public health and clinical recommendations could be based. The purpose of the present work was to update the prior systematic review and include studies published up to October 2015. METHODS: Using the electronic databases MEDLINE and EMBASE, we identified RCTs which assessed the combined effect of exercise training and nutritional supplementation on muscle strength, muscle mass, or physical performance in subjects aged 60 years and over. Study selection and data extraction were performed by two independent reviewers. RESULTS: The search strategy identified 21 additional RCTs giving a total of 37 RCTs. Studies were heterogeneous in terms of protocols for physical exercise and dietary supplementation (proteins, essential amino acids, creatine, beta-hydroxy-beta-methylbuthyrate, vitamin D, multi-nutrients, or other). In 79% of the studies (27/34 RCTs), muscle mass increased with exercise but an additional effect of nutrition was only found in 8 RCTs (23.5%). Muscle strength increased in 82.8% of the studies (29/35 RCTs) following exercise intervention, and dietary supplementation showed additional benefits in only a small number of studies (8/35 RCTS, 22.8%). Finally, the majority of studies showed an increase of physical performance following exercise intervention (26/28 RCTs, 92.8%) but interaction with nutrition supplementation was only found in 14.3% of these studies (4/28 RCTs). CONCLUSION: Physical exercise has a positive impact on muscle mass and muscle function in healthy subjects aged 60 years and older. The biggest effect of exercise intervention, of any type, has been seen on physical performance (gait speed, chair rising test, balance, SPPB test, etc.). We observed huge variations in regard to the dietary supplementation protocols. Based on the included studies, mainly performed on well-nourished subjects, the interactive effect of dietary supplementation on muscle function appears limited. [less ▲]

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See detailUne courbe rentrante dans le contentieux administratif ? Quand le législateur veut éviter ou neutraliser l’annulation par le Conseil d’Etat
Pâques, Michel ULg

in Revue de la Faculté de Droit de l'Université de Liège (2017), 2017-1

DOCTRINE La Faculté de droit de l’Université de Liège. Notes historiques succinctes, par Patrick Wautelet Gardez votre carte d’identité en poche, par Frédéric Bouhon Les illégalités que l’on ne voit pas ... [more ▼]

DOCTRINE La Faculté de droit de l’Université de Liège. Notes historiques succinctes, par Patrick Wautelet Gardez votre carte d’identité en poche, par Frédéric Bouhon Les illégalités que l’on ne voit pas : Enseignements tirés du droit de l’arbitrage, par Olivier Caprasse Les barèmes de rémunération : la périlleuse transition de l’âge à l’expérience pour éliminer la discrimination, par Jacques Clesse De l’information (légale) à l’action (illégale) : Tests génétiques et technologies de pouvoir, par Catherine Fallon « La madone et la putain » : Quand les stéréotypes de genres influencent la perception de la légalité des violences sexuelles et le traitement de la réaction sociale à l’égard des femmes, par Serge Garcet Les circulaires administratives fiscales illégales, par Luc Herve Le licenciement en cas de congé pour assistance à un proche gravement malade et de congé pour soins palliatifs : une inconstitutionnalité créée par la Cour constitutionnelle ? Par Fabienne Kéfer Des tribulations des actions possessoires : entre illégalité et inconstitutionnalité, par Pascale Lecocq Lorsque l’Union européenne réaffirme sa norme : la réponse par l’absurde aux craintes de ses citoyens ? Par Quentin Michel L’intervention de l’assureur dans le procès pénal : la défense de ton assuré tu assumeras ? Par Olivier Michiels Défaut de motivation formelle et droit administratif de la sécurité sociale : des illégalités à redécouvrir ? Par Hugo Mormont Une courbe rentrante dans le contentieux administratif ? Quand le législateur veut éviter ou neutraliser l’annulation par le Conseil d’État, par Michel Pâques Au nom de l’ordre pénitentiaire. L’impératif de sécurité, générateur d’illégalités ? Par Vincent Seron Quis custodiet ipsos custodies ? Libres propos sur les violations de la légalité couvertes, admises, entérinées ou commises par les cours suprêmes, par Nicolas Thirion The Dodd-Frank Bounty Program: Disclosing the Unknown (and Getting Handsomely Paid For It), par François vander Mensbrugghe La « discrimination à rebours » au sein du marché intérieur : une illégalité qu’il ne faut pas voir au niveau européen ? Par Pieter van Cleynenbreugel La transaction pénale : des illégalités visibilisées aux ill(n)égalités moins visibles, par Charlotte vanneste Illégalité et jugements étrangers, par Patrick Wautelet VIE DU DROIT Autour et alentours des Leçons inaugurales de la Faculté de droit, de science politique et de criminologie de l’Université de Liège, par Patrick Wautelet Du zéro-vivant au zéro-mort, par André Dumoulin Le notaire refuse, par Gabriel Rasson Décider ensemble ou vivre ensemble ? Quelques pas de danse sur un air de tango, par Frédéric Bouhon D’une victime à l’autre : Posture ou (im)posture victimaire ? Par Serge Garcet Pouvoir politique et audace des juges, par Geoffrey Grandjean Hommage à Didier Matray, par Olivier Caprasse, Didier Matray et Pascale Lecocq [less ▲]