Effect of New Synthetic PEGylated Ferulic Acids in Comparison to Ferulic Acid and Commercial Surfactants on the Properties of Wheat Flour Dough and Bread

in Journal of the Science of Food and Agriculture (in press)

BACKGROUND: Ferulic acid esterified with poly(ethylene glycol) with three different average molecular weights (200, 400 and 1000 g/mol) was studied in breadmaking. The effects of these antioxidants on the ... [more ▼]

BACKGROUND: Ferulic acid esterified with poly(ethylene glycol) with three different average molecular weights (200, 400 and 1000 g/mol) was studied in breadmaking. The effects of these antioxidants on the properties of wheat flour dough and bread were analyzed and compared with those obtained with ferulic acid and two commercial surfactants, diacetyl tartaric acid ester of mono- and diglycerides and sodium stearoyl lactylate. Farinographic and alveographic methods as well as weight, volume and bread firmness measurements were used for this purpose. <br /> <br />RESULTS: Such as ferulic acid, when the PEGylated derivatives were implemented in the dough (5000 ppm), it accelerated its breakdown and decreased its rheological properties. However, it allowed to avoid the important diminution of loaf volume observed when dough supplemented with ferulic acid was baked. That decrease in volume was related to the inhibition of the yeast (Saccharomyces cerevisae) by the unesterified ferulic acid. Moreover, two of the PEGylated ferulic acids even contributed to an increase of loaf volumes (5-6%) and demonstrated crumb softener properties. <br /> <br />CONCLUSION: The addition of ferulic acid in wheat flour dough caused the inhibition of the yeast, which resulted in decreased bread volume. That effect could be avoid by the esterification of ferulic acid with poly(ethylene glycol). [less ▲]

Franz Thedieck (1900-1995) und das Verhältnis zwischen Wissenschaft und Politik "von Weimar nach Bonn": eine biographische Annäherung

in Thomes, Paul (Ed.) Zwischen Narration und Methode. Neue Impulse in der historischen Biographieforschung (in press)

Documentário e mal-entendido. Retorno sobre uma primeira filmagem no Brasil

in Stols, Eddy; Mascaro, Luciana; Bueno, Clodoaldo (Eds.) Brasil e Bélgica: Cinco Séculos de Conexões e Interação (in press)

Réexamen du dessin du codex miscellaneus de Montserrat (P. Montserrat inv. nr. 154 = MP³ 2916.41)

in Aegyptus (in press), 90

New interpretation of the drawing of a mythological hero in the 4th Montserrat codex miscellaneus.

The ocean bomb radiocarbon inventory revisited

in Radiocarbon (in press)

Large discrepancies exist among data-based estimates and model reconstructions of the ocean bomb radiocarbon inventory. In order to resolve this gap, it has been proposed that the CO2 piston veloc- ity ... [more ▼]

Large discrepancies exist among data-based estimates and model reconstructions of the ocean bomb radiocarbon inventory. In order to resolve this gap, it has been proposed that the CO2 piston veloc- ity should be revised downward (Sweeney et al., 2007; Müller et al., 2008). Here we compare the transient 14C distributions in the ocean obtained with different formulations of the isotopic ratio commonly used in modeling studies. It is found that both the CO2 increase and the air-sea CO2 flux significantly contribute to the 1990 ocean bomb radiocarbon inventory, by around 10% each. Moreover, these two processes explain more than 25% of the inventory difference be- tween 1974 and 1990. These results imply that, as already argued by Naegler (2009), inventories based on observations which lack infor- mation about CO2 invasion are underestimated. Further, this work allows to gain insight into the reasons for discrepancies among model results. It suggests that while a comprehensive isotopic formulation is needed when addressing the global radiocarbon cycle, a simplified form is more relevant for model calibration and piston velocity assess- ment based on currently available bomb radiocarbon inventories. [less ▲]

On the Number of Abelian Bordered Words

in Lecture Notes in Computer Science (in press)

In the literature, many bijections between (labeled) Motzkin paths and various other combinatorial objects are studied. We consider abelian (un)bordered words and show the connection with irreducible ... [more ▼]

In the literature, many bijections between (labeled) Motzkin paths and various other combinatorial objects are studied. We consider abelian (un)bordered words and show the connection with irreducible symmetric Motzkin paths and paths in Z not returning to the origin. This study can be extended to abelian unbordered words over an arbitrary alphabet and we derive expressions to compute the number of these words. In particular, over a 3-letter alphabet, the connection with paths in the triangular lattice is made. Finally, we study the lengths of the abelian unbordered factors occurring in the Thue--Morse word. [less ▲]

A Balance Equation Determines a Switch in Neuronal Excitability

in PLoS Computational Biology (in press)

We use the qualitative insight of a planar neuronal phase portrait to detect an excitability switch in arbitrary conductance-based models from a simple mathematical condition. The condition expresses a ... [more ▼]

We use the qualitative insight of a planar neuronal phase portrait to detect an excitability switch in arbitrary conductance-based models from a simple mathematical condition. The condition expresses a balance between ion channels that provide a negative feedback at resting potential (restorative channels) and those that provide a positive feedback at resting potential (regenerative channels). Geometrically, the condition imposes a transcritical bifurcation that rules the switch of excitability through the variation of a single physiological parameter. Our analysis of six di erent published conductance based models always nds the transcritical bifurcation and the associated switch in excitability, which suggests that the mathematical predictions have a physiological rel- evance and that a same regulatory mechanism is potentially involved in the excitability and signaling of many neurons. [less ▲]

Genetic analysis of longitudinal measurements of feed intake in Piétrain sire lines

in Journal of Animal Science (in press)

Dendritic cells in Barrett's esophagus carcinogenesis: an inadequate microenvironment for antitumor immunity?

in American Journal of Pathology (in press)

Adult Bone Marrow Neural Crest Stem Cells and Mesenchymal Stem Cells are not able to Replace Lost Neurons in Acute MPTP-lesioned Mice

in PLoS ONE (in press)

Adult bone marrow stroma contains multipotent stem cells (BMSC) that are a mixed population of mesenchymal and neural-crest derived stem cells. Both cells are endowed with in vitro multi-lineage ... [more ▼]

Adult bone marrow stroma contains multipotent stem cells (BMSC) that are a mixed population of mesenchymal and neural-crest derived stem cells. Both cells are endowed with in vitro multi-lineage differentiation abilities, then constituting an attractive and easy-available source of material for cell therapy in neurological disorders. Whereas the in vivo integration and differentiation of BMSC in neurons into the central nervous system is currently matter of debate, we report here that once injected into the striatum of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice, pure populations of either bone marrow neural crest stem cells (NCSC) or mesenchymal stem cells (MSC) survived only transiently into the lesioned brain. Moreover, they do not migrate through the brain tissue, neither modify their initial phenotype, while no recovery of the dopaminergic system integrity was observed. Consequently, we tend to conclude that MSC/NCSC are not able to replace lost neurons in acute MPTP-lesioned dopaminergic system through a suitable integration and/or differentiation process. Altogether with recent data, it appears that neuroprotective, neurotrophic and anti-inflammatory features characterizing BMSC are of greater interest as regards CNS lesions management. [less ▲]