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See detail(Bé)vues du futur. Les imaginaires visuels de la dystopie (1840-1940)
Stienon, Valérie ULg; Dessy, Clément

Book published by Presses Universitaires Septentrion (2015)

Aujourd’hui inscrite au cœur des cultures télévisuelle et adolescente, la dystopie possède une histoire riche pourtant méconnue. Cette forme d’expression qui mêle projection dans le futur et vision ... [more ▼]

Aujourd’hui inscrite au cœur des cultures télévisuelle et adolescente, la dystopie possède une histoire riche pourtant méconnue. Cette forme d’expression qui mêle projection dans le futur et vision critique d’une société révèle les enjeux majeurs des époques qu’elle a traversées. Explorer ses caractéristiques visuelles sur un siècle, de 1840 à la Seconde Guerre mondiale, permet d’observer les lignes de forces d’un imaginaire central dans la littérature et les arts. L’imaginaire dystopique ne touche pas seulement à l’iconographie. Il concerne aussi les ressources textuelles de la description, la circulation transmédiatique des fictions et la définition même d’un univers souvent improprement qualifié par les étiquettes de fantastique et de science-fiction. Ce volume collectif abondamment illustré offre un aperçu chronologique empruntant ses approches à l’analyse de texte, à l’étude de l’image fixe ou animée, à la sociologie des auteurs et de l’édition, ainsi qu’à l’histoire des représentations. Il se centre sur les aires d’expression française, qui ont leurs propres spécificités, distinctes des réalisations anglo-saxonnes. Envisageant tant les œuvres paralittéraires que celles d’avant-garde, il met à l’honneur une production foisonnante, encore peu étudiée : de Souvestre à Bartosch, sans oublier Henriot et Robida, de l’eschatologie biblique à la poétique des ruines de la ville moderne, en passant par l’archéologie rétrofuturiste et l’imaginaire des fourmis. [less ▲]

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See detailOxidative stress or not in healthy older subjects?
PINCEMAIL, Joël ULg; CHRISTELBACH, Sophie ULg; RICOUR, Céline ULg et al

in OCC2015 (2015, June)

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See detailChanges in Activity Patterns and Intergroup Relationships After a Significant Mortality Event in Commensal Long- Tailed Macaques (Macaca Fascicularis) in Bali, Indonesia
Brotcorne, Fany ULg; Fuentes, Agustin; Wandia, I Nengah et al

in International Journal of Primatology (2015), 36(3), 548566

Little is known regarding behavioral and social responses of free-ranging primates to demographic changes emerging from significant mortality events. Here, we report on the activity patterns and ... [more ▼]

Little is known regarding behavioral and social responses of free-ranging primates to demographic changes emerging from significant mortality events. Here, we report on the activity patterns and intergroup sociospatial relationships in a commensal population of long-tailed macaques (Macaca fascicularis) in Bali, Indonesia, that underwent a significant mortality event in summer 2012. During the period of interest, we noted heightened mortality in three of the five social groups present in this population, with adult females and juveniles experiencing higher mortality rates than adult and subadult males. Limited diagnostic data regarding pathogen identification and a lack of any conclusive etiology of the deaths prevent our ascertainment of the agent(s) responsible for the observed mortality, but given the characteristics of the event we assume it was caused by a transmissible disease outbreak. Comparing the pre- and postmortality event periods, we found significant differences in activity patterns, including a decreased proportion of affiliation in adult females. This result is likely indicative of enhanced social instability induced by the high mortality of adult females that constitute the stable core of macaque social structure. A higher social tension between groups after the mortality event was indicated by more frequent and intense agonistic intergroup encounters. Intergroup conflict success was inversely proportional to the rate of mortality a group suffered. Our results illustrate how changes in demographic structure caused by significant mortality events may have substantial consequences on behavior and social dynamics in primate groups and at the level of a population. [less ▲]

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See detailTriiodothyronine-predominant Graves’ disease in childhood: detection and therapeutic implications
HARVENGT, Julie ULg; boizeau, priscilla; chevenne, didier et al

in European Journal of Endocrinology (2015), 172(6), 715-723

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See detailPromoting Competition at the Digital Age with an Application to Belgium
Lefevre, Mélanie ULg

Conference (2015, June)

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See detailGalectin-3 and Suppression of Tumorigenicity 2 measurement in participants at the “Tor des Géants”
LE GOFF, Caroline ULg; Kaux, Jean-François ULg; Gergelé, Laurent et al

in Radmann, A; Hedenborg, S; Tsolakidis, E (Eds.) 20th annual Congress of the EUROPEAN COLLEGE OF SPORT SCIENCE - BOOK OF ABSTRACTS0th annual Congress of the EUROPEAN COLLEGE OF SPORT SCIENCE - BOOK OF ABSTRACTS (2015, June)

Introduction: Gal-3 is a carbohydrate binding lectin produced by macrophages, upregulated in hypertrophied heart, emerging as a mediator for fibrosis development and cardiac remodeling. ST2 is a family ... [more ▼]

Introduction: Gal-3 is a carbohydrate binding lectin produced by macrophages, upregulated in hypertrophied heart, emerging as a mediator for fibrosis development and cardiac remodeling. ST2 is a family member of IL-1 receptors initially known for its role in immunological processes. It has a potential role in the cardiac pathogenesis. These receptors are led in cardiomyocytes and fibroblasts due to a mechanical stress. We aimed to examine the evolution of Gal-3 and ST2 in trailers who ran one of the most challenging ultra-marathon in the world: the Tor des Géants (330 km, altitude range: 24000m). Methods: Levels of plasma Gal-3 and ST2 were determined at 4 times: before the start, after 158km, at the end and 3 days after the end of the race in 33 trailers. Samples were directly centrifuged and frozen at -80°C. Gal-3 measurement was performed on the VIDAS (Biomerieux) and ST2 was analyzed with the Presage ST2 Assay (Critical Diagnostic). The reference values are <17.8ng/mL for Gal-3 and <35ng/mL for ST2. Statistica was used for the statistical analysis (ANOVA). We calculated the difference between the different time and expressed in delta: Δ1=(T2-T1)/T1*100, Δ2=(T3-T2)/T2*100, Δ3=(T4-T3)/T3*100, Δ4=(T3-T1)/T1*100, Δ5=(T4-T1)/T1*100. After that, we tried to correlate the delta between them (results= R(p-value)). Results were considered as significant with p<0.05. Results: Plasmatic levels of Gal-3 did never exceed the cut-off of 17.8ng/mL, except for 1 trailer in T2. A slight increase of levels of Gal-3 was observed at T2 (min-max:7.5-17.6ng/mL). These ones did not vary a lot at T3 (min-max:7.0- 18.8ng/mL) but return to normality at T4 (min-max:6.0-12.8ng/mL). For ST2, at T1, 12 subjects had plasmatic levels above the reference value of 35ng/ml. At T2, only 2 trailers blood samples were still in the reference interval. Indeed, a great increase of ST2 plasmatic levels observed (min-max:18.8-158.8ng/mL). A slight decrease of ST2 levels was observed at T3, but only one subject had a value below 30ng/ml (min-max:20.1-182.7ng/mL). However, a subject had still plasmatic levels above T2 values. A return to normality was observed at T4 with 16 trailers blood levels in the reference interval (min-max:12.0-56.4ng/mL). We observed an increase for Gal-3 and ST2, above the reference values only for ST2. We noted for both a decrease up to the normal values 3 days after the trail. For the correlation between deltas, we observed that Gal-3 and ST2 are correlated for each delta. Discussion: A logical correlation is observed between Gal-3 andST2 as they are involved in cardiac fibrosis and inflammation. But we do not known why it is not in the same proportion. We know that some trailers take NSAIDs and painkillers during the race. The results of this study demonstrate that this exercise was associated with biochemical abnormalities that may reflect adverse consequences on cardiac structure as fibrosis. However, ST2 values were higher, perhaps due to a mechanical stress more than a cardiac stress. Gal-3 is perhaps then more cardiospecific than ST2. [less ▲]

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See detailDoes yellow eel prefer old pool and weir or new vertical slot fish pass during their upstream migration?
Nzau Matondo, Billy ULg; Dierckx, Arnaud ULg; Benitez, Jean-Philippe ULg et al

Conference (2015, June)

The hydroelectric dam of Lixhe in the River Meuse, 323km upstream from the North Sea at the entry of Belgium near the frontier with the Netherlands is equipped with two basin fish-passes: – the old pool ... [more ▼]

The hydroelectric dam of Lixhe in the River Meuse, 323km upstream from the North Sea at the entry of Belgium near the frontier with the Netherlands is equipped with two basin fish-passes: – the old pool-and-weir configuration (OFP) operates at low discharge (0.13m3/s) and – the new vertical-slot configuration (NFP) operating at high discharge (1m3/s) with attraction flow (1.5m3/s). However, the utilization rate of these fish-passes by the incoming yellow eels remains unknown, because the trap of NFP is not adapted to retain anguillids and small species. Yet, such knowledge is crucial to improve the inland colonization of the species and to increase our understanding of fish-pass utilization given its particular swimming mode. In season 2013, eels caught two times a week using a cone-trap pool in the OFP and net traps in the NFP, were tagged and released the same day 0.3km downstream (n = 396eels). The utilization of OFP and NFP was studied using automatic RFID transponder detection antennas placed in upstream basins of the fish-passes, during years 2013 and 2014. Results revealed that the OFP was the preferred migration route of eels (eel numbers, OFP:NFP, 2013= 88:51 and 2014= 41:16, χ²-test, p<0.0001), which was also used earlier in season. Eels displayed fidelity to their catch fish-passes (>70% of the detected eels, annually). Detection rate was high in the year of eel tagging (2013: 35.1%) before decreasing in the following year (2014: 14.4%). Eels used these fish-passes the night from 22:00 to 04:00, at 14-26°C, river flow <200m³/s and whenever waxing and waning phases of moonlight. Our results provide insight into the utilization of fish-passes by migrating eels. The study suggests further reflection before removing the old fish-pass in large rivers and to think about the eel attractiveness and comfort when the construction of a new fish pass is planned. [less ▲]

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See detailGenetic depletion of the dual specificity protein phosphatase DUSP3 promotes LLC Lung tumour metastasis
Vandereyken, Maud ULg; Amand, Mathieu ULg; Van Overmeire, Eva et al

Conference (2015, June)

DUSP3, also called Vaccinia-H1 Related (VHR) is a small dual specificity phosphatase dephosphorylating both tyrosine and serine/threonine phosphorylated residues. DUSP3 plays an important role in cell ... [more ▼]

DUSP3, also called Vaccinia-H1 Related (VHR) is a small dual specificity phosphatase dephosphorylating both tyrosine and serine/threonine phosphorylated residues. DUSP3 plays an important role in cell cycle regulation and is up-regulated in several human cancers. The physiological role of this phosphatase is, however, poorly understood. We have recently generated a DUSP3 knockout mouse by homologous recombination. The obtained mice have no spontaneous phenotype or pathology. However, DUSP3 deficiency prevented neo-vascularization of subcutaneously transplanted Matrigel plugs and Lung Lewis Carcinoma (LLC) tumours, suggesting an involvement of DUSP3 in tumour angiogenesis. Considering the importance of angiogenesis in metastatic formation, our study aimed to investigate the role of DUSP3 in metastatic dissemination. To do so, we used the LLC experimental metastasis model that shortcuts the intravasation/extravasation processes by injecting intravenously the LLC and the B16 (metastatic melanoma cell line) cells. Surprisingly, LLC, but not B16, lung metastasis developed twice faster in DUSP3-KO than WT mice. The enhanced LLC metastatic growth in DUSP3-/- mice was transferable to WT mice via DUSP3-/- bone marrow adoptive transfer, suggesting an involvement of the hematopoietic compartment in the observed phenotype. This was confirmed by a higher infiltration of neutrophils and macrophages in the lungs of DUSP3-KO compared to WT mice after LLC injection. This infiltration was correlated with higher expression of the chemokine receptor CCR2 in LLC-bearing DUSP3-KO lungs macrophages. Interestingly, LLC, but not B16 cells, were found to secrete high level of CCL2/MCP1, the CCR ligand chemokine. In line with this observation, we found that DUSP3-/- bone marrow derived-macrophages have a higher migration potential in response to LLC, but not B16, -conditionned medium. Altogether, our results suggest that DUSP3 plays an important role in metastatic dissemination/growth by a mechanism involving the control of CCR2-CCL2 chemoattraction axis in macrophages. [less ▲]

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See detailThe site of administration influences both the type and the magnitude of the immune response induced by DNA vaccine electroporation
Vandermeulen, G; Vanvarenberg, K; De Beuckelaer, A et al

in Vaccine (2015), 33

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See detailQuaternary prevention: first, do not harm - Editorial
Jamoulle, Marc ULg

in Revista Brasileira de Medicina de Família e Comunidade (2015), 10(35), 1-3

Clinical prevention, under the influence of public health, has been organised in a chronological manner since the middle of the 20th century. A paradigm shift from a chronological to a constructivist ... [more ▼]

Clinical prevention, under the influence of public health, has been organised in a chronological manner since the middle of the 20th century. A paradigm shift from a chronological to a constructivist relationship-based preventive pattern of care offers new insights into the practice of doctors. This paradigm shift brings to light the concept of quaternary prevention, a critical look at medical activities with an emphasis on the need not to harm. Quaternary prevention addresses the fundamental question of what constitutes too much or too little medicine. It is the fourth form of disease prevention, but also the fourth frame of action for family doctors [less ▲]

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See detailTeaching and learning Quaternary prevention
Gomes, Luis Enrique; Gusso, Gustavo; Jamoulle, Marc ULg

in Revista Brasileira de Medicina de Família e Comunidade (2015), 10(35), 1-14

This article presents an overview of different techniques and skills required for teaching and learning quaternary prevention (P4). It adopts the Expertise Model that defines the competences required in ... [more ▼]

This article presents an overview of different techniques and skills required for teaching and learning quaternary prevention (P4). It adopts the Expertise Model that defines the competences required in P4 for each level: novice, competent, proficient, and expert. This should be used as a step-wise roadmap for teachers in order to achieve high standard levels of performance. This is complemented by a list of methods used in teaching and assessment of learners’ performance and competence. By covering a range of learning and teaching issues, those who aim to teach quaternary prevention can explore the proposed framework. Quaternary prevention is a research and teaching fertile medical field that requires the integration of different areas such as health service organization, epidemiology, communication skills, and andragogy either at the macro or the micro levels health related activities. [less ▲]

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See detailThe words of prevention, part I: changing the model
Jamoulle, Marc ULg; Gavilan, Enrique; Cardoso, Raquel Val et al

in Revista Brasileira de Medicina de Família e Comunidade (2015), 10(35), 1-9

ABSTRACT Objective: This part I article explores the different meanings of relevant keywords for General Practice/Family Medicine (GP/FM) in the prevention domain. The aim is to contribute to information ... [more ▼]

ABSTRACT Objective: This part I article explores the different meanings of relevant keywords for General Practice/Family Medicine (GP/FM) in the prevention domain. The aim is to contribute to information process in GP/FM by keeping in line with the main terms used in health care organization. Methods: Important keywords for GP/FM in the prevention domain were selected. Then, a search was carried out on the main sources in GP/FM databases, as well as in Medical Subject Heading and major terminological databases available online. Results and Discussion: There is discrepancy between the conceptual contents of major prevention models amongst the usual bibliographic sources of knowledge in GP/FM in particular and medicine in general. Conclusion: For GP/FM, distribution of preventive activities is now firmly established on a new constructivist model, privileging the doctor-patient relationships and introducing a cybernetic thinking on the health care activities with a special commitment to ethics and the positive duty of beneficence. [less ▲]

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See detailThe words of prevention, part II: ten terms in the realm of quaternary prevention
Jamoulle, Marc ULg; Gavilan, Enrique; Cardoso, Raquel Val et al

in Revista Brasileira de Medicina de Família e Comunidade (2015), 10(35), 1-9

ABSTRACT Objective: This part II article about the ‘words of prevention’ presents in a terminological way the content of ten current concepts used in the prevention domain which are closely linked to ... [more ▼]

ABSTRACT Objective: This part II article about the ‘words of prevention’ presents in a terminological way the content of ten current concepts used in the prevention domain which are closely linked to quaternary prevention: (1) overinformation, (2) overdiagnosis, (3) medically unexplained symptoms, (4) overmedicalisation, (5) incidentaloma, (6) overscreening, (7) overtreatment, (8) shared decision making, (9) deprescribing, and (10) disease mongering. Methods: with the support of the laboratory team of the University of Rouen, France, which is dedicated to medical terminology and semantic relationships, it was possible to utilize a graphic user interface (called DBGUI) allowing the construction of links for each of chosen terms, and making automatic links to MeSH, if any. Those concepts are analyzed in their environment in current literature, as well as in their MeSH counterparts, if any, and related semantic online terminologies. Results and Discussion: The rules in terminological development aspire to cover the whole field of a concept and in the meantime, it helps to avoid the noise due to proxy and not exactly related issues. This refers to exhaustivity and specificity in information retrieval. Our finds show that referring to MeSH only in information retrieval in General Practice/Family medicine can induce much noise and poor adequacy to the subject investigated. Conclusion: Gathering concepts in specially prepared terminologies for further development of ontologies is a necessity to enter in the semantic web area and the era of distributed data. [less ▲]

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See detailEarly evolution of large microorganisms with cytological complexity revealed by microanalyses of 3.4 Ga organic-walled microfossils.
Sugitani; Mimura, K; Takeuchi, M et al

in Geobiology (2015)

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See detailIdentification of the main parameters controlling the plasticity of ceramic pastes: The case study of the Marrakech region (Morocco)
El Boudour El Idrissi, Hicham ULg; Daoudi, Lahcen; Fontaine, François ULg et al

Poster (2015, June)

Numerous traditional ceramic workshops occur within a range of 10 to 80 km around the city of Marrakech. Our study aims to identify the main parameters controlling the plasticity of pastes used by the ... [more ▼]

Numerous traditional ceramic workshops occur within a range of 10 to 80 km around the city of Marrakech. Our study aims to identify the main parameters controlling the plasticity of pastes used by the artisans. To reach this goal, we characterize by X-ray diffraction, granulometry and plasticity index (PI) the local raw clayey material. The investigation of 26 whole pastes shows the dominance of quartz (20 to 50%) and clay minerals (25 to 60%) with K-feldspar (2 to 17%), plagioclase (2 to 25%), calcite (0 to 18%), dolomite (0 to 15%), goethite (0 to7%) and trace of hematite and anhydrite (< 3%). Amphibole occurs in trace (< 5%) but only in some samples. The clay minerals are diversified, including illite (10 to 40%), kaolinite (2 to 15%), mixed-layer (ML) (0 to 10%), smectite, vermiculite and chlorite (0 to 5%), and pyrophyllite-talc association (0 to 8%). Sepiolite (12%) is only present in one paste. The grain size is made by variable proportions of sand (5 to 65%), silt (12 to 53%) and clayey fraction (18 to 66%). The Plasticity index (PI) indicates the presence of two principals groups of pastes. (1) The first group is characterized by PI values ranging between 15 to 18. Their moderate plasticity behavior is related either to the low rate of clayey fraction and/or to the absence of plastic clays like smectites and mixed layer with smectitic sheets. (2) The PI of second group ranges between 20 to 32. The high plasticity values are influenced by the presence of specific clayey minerals like talc-pyrophyllite or sepiolite, or by the high content of smectite plus smectitic mixed-layers within the clayey (< 2 micron) fraction. Only one sample without any of these plastic minerals but with a high content of clayey fraction is characterized by a high PI value (24). We concluded that the workability of ceramic paste in Marrakech region is controlled by a combination of factors, dominated by the grain size distribution and the content in plastic clay minerals within the fine fraction. [less ▲]

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See detailA new formulation of state estimation in distribution systems including demand and generation states
Rousseaux, Patricia ULg; Toubeau, Jean-François; De Grève, Zacharie et al

in proceeedings of the 2015 Power Tech conference (2015, June)

Distribution system state estimation faces a major difficulty: the lack of real-time measurements. This imposes to add information, usually pseudo-measurements from historical data. This paper proposes a ... [more ▼]

Distribution system state estimation faces a major difficulty: the lack of real-time measurements. This imposes to add information, usually pseudo-measurements from historical data. This paper proposes a different, novel formulation of state estimation relying on the classification of loads into components (e.g. residential, commercial, etc.) and accounting for dispersed generation. The approach “by-passes” the use of pseudo-measurements by expressing the medium-voltage bus injections as functions of a small number of active power components at low-voltage level, treated as additional state variables. The injections at medium-voltage buses become equality constraints. A procedure to identify the above functions is detailed, which takes advantage of data collected by smart meters. [less ▲]

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See detailA dynamic simulation approach to identify additional reactive reserves against long-term voltage instability
Papangelis, Lampros ULg; Panciatici, Patrick; Debry, Marie-Sophie et al

in Proc. of IEEE PES 2015 PowerTech conference (2015, June)

A simple method is proposed to identify additional reactive reserves enabling to counteract long-term voltage instability after a large disturbance. In contrast to the many references based on power flow ... [more ▼]

A simple method is proposed to identify additional reactive reserves enabling to counteract long-term voltage instability after a large disturbance. In contrast to the many references based on power flow calculations, the method resorts to dynamic simulation. The post-disturbance system evolution is simulated in the presence of time-varying shunt susceptances with specified rate of change. This allows to deal with dynamic issues such as the required speed of the additional reactive power sources, or the onset of unstable electromechanical oscillations. Furthermore, a compromise is sought between the speed of action and the volume of additional compensation. The method is demonstrated on a detailed model of the Nordic test system. [less ▲]

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