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See detailEffect of stress path on the miniaturizatio size effect for nickel polycrystals
Keller, Clement; Hug, Eric; Duchene, Laurent ULg et al

Conference (2015, January 04)

The mechanical behavior of mettalic materials deeply depends on the size of samples. For specimen dimensions de creasing from a few millimeters to a few micrometers, the general observed trend is a ... [more ▼]

The mechanical behavior of mettalic materials deeply depends on the size of samples. For specimen dimensions de creasing from a few millimeters to a few micrometers, the general observed trend is a softening of the mechanical behavior in tension which affects the stress level and the strain hardening. This effect is triggered by the derease of the number of grains across the thickness ( also called thickness"t" over grain size "d" ratio). The objective of this work is to provide new experimental results in order to analyse the miniaturization size effects for various stress paths without strain gradients across the thickness of the samples. To this aim, experimental tensil tests, large tensile tests and shear tests have been performed on Ni sheets ( 0.5mm) with various grain sizes ensuring different t/d ratios. Results show that the miniaturization softening is affected by triaxiality, the larger is this parameter, the lower is the mechanicval softening. These features seem to be linked to surface effects which are larger for low triaxiality stress paths. Attempts of numerical simulations using strain gradient crystal plasticity model are also performed to confirm the role played by surface effects. [less ▲]

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See detailBasin-scale partitioning of Greenland ice sheet mass balance components (2007–2011)
Andersen, M.L.; Stenseng, L.; Skourup, H. et al

in Earth and Planetary Science Letters (2015), 409

The current deficit in Greenland ice sheet mass balance is due to both a decrease in surface mass balance (SMB ) input and an increase in ice discharge (D ) output. While SMB processes are beginning to be ... [more ▼]

The current deficit in Greenland ice sheet mass balance is due to both a decrease in surface mass balance (SMB ) input and an increase in ice discharge (D ) output. While SMB processes are beginning to be well captured by observationally-constrained climate modeling, insight into D is relatively limited. We use InSAR-derived velocities, in combination with ice thickness observations, to quantify the mass flux (F ) across a flux perimeter around the ice sheet at ∼1700 m elevation. To quantify D , we correct F for SMB , as well as changes in volume due to ice dynamics, in the area downstream of the gate. Using a 1961–1990 reference climatology SMB field from the MAR regional climate model, we quantify ice sheet mass balance within eighteen basins. We find a 2007–2011 mean D of View the MathML source. We find a 2007–2011 mean total mass balance of View the MathML source, which is equal to a 0.73 mm yr−1 global sea level rise contribution. This mass loss is dominated by SMB, which accounts for 61% of mass loss in the basins where partitioning is possible. [less ▲]

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See detailFood provioning influences ranging patterns in northern pigtailed macaques (Macaca leonina)
Huynen, Marie-Claude ULg; Savini, Tommaso ULg; Asensio, Norberto et al

in International Journal of Primatology (2015, January)

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See detailMetabolic reprogramming in transformed mouse cortical astrocytes: a proteomic study.
Bentaib, Azeddine; De Tullio, Pascal ULg; Chneiweiss, Herve et al

in Journal of proteomics (2015), 113

Metabolic reprogramming is thought to play a key role in sustaining the survival and proliferation of cancer cells. These changes facilitate for example the uptake and release of nutrients required for ... [more ▼]

Metabolic reprogramming is thought to play a key role in sustaining the survival and proliferation of cancer cells. These changes facilitate for example the uptake and release of nutrients required for nucleotide, protein and lipid synthesis necessary for macromolecule assembly and tumor growth. We applied a 2D-DIGE (Two-Dimensional Differential in-Gel Electrophoresis) quantitative proteomic analysis to characterize the proteomes of mouse astrocytes that underwent in vitro cancerous transformation, and of their normal counterparts. Metabolic reprogramming effects on enzymatic and structural protein expression as well as associated metabolites abundance were quantified. Using enzymatic activity measurements and zymography, we documented and confirmed several changes in abundance and activity of various isoenzymes likely to participate in metabolic reprogramming. We found that after transformation, the cells increase their expression of glycolytic enzymes, thus augmenting their ability to use aerobic glycolysis (Warburg effect). An increased capacity to dispose of reducing equivalents through lactate production was also documented. Major effects on carbohydrates, amino acids and nucleotides metabolic enzymes were also observed. Conversely, the transformed cells reduced their enzymatic capacity for reactions of tricarboxylic acid oxidation, for neurotransmitter (glutamate) metabolism, for oxidative stress defense and their expression of astroglial markers. BIOLOGICAL SIGNIFICANCE: The use of a global approach based on a 2D DIGE analysis allows obtaining a comprehensive view of the metabolic reprogramming undergone by astrocytes upon cancerous transformation. Indeed, except for a few enzymes such as pyruvate carboxylase and glutaminase that were not detected in our initial analysis, pertinent information on the abundance of most enzymes belonging to pathways relevant to metabolic reprogramming was directly obtained. In this in vitro model, transformation causes major losses of astrocyte-specific proteins and functions and the acquisition of metabolic adaptations that favor intermediate metabolites production for increased macromolecule biosynthesis. Thus our approach appears to be readily applicable for the investigation of changes in protein abundance that determine various transformed cell phenotypes. It could similarly be applied to the evaluation of the effects of treatments aimed at correcting the consequences of cell transformation. [less ▲]

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See detailEffect of stress path on the miniaturization size effect for nickel polycrystals
Keller, Clement; Hug, Eric; Habraken, Anne ULg et al

in International Journal of Plasticity (2015), 64

The mechanical behavior of metallic materials deeply depends on the size of samples. For specimen dimensions decreasing from a few millimeters to a few micrometers, the general observed trend is a ... [more ▼]

The mechanical behavior of metallic materials deeply depends on the size of samples. For specimen dimensions decreasing from a few millimeters to a few micrometers, the general observed trend is a softening of the mechanical behavior in tension which affects the stress level and the strain hardening. The objective of this work is to provide new experimental results in order to analyze the miniaturization size effects for various stress paths without strain gradients across the thickness of the samples. To this aim, experimental tensile tests, large tensile tests and shear tests have been performed on Ni sheets with various grain sizes. Results show that the miniaturization softening is affected by triaxiality, the larger is this parameter, the lower is the mechanical softening. These features seem to be linked to surface effects which are larger for low triaxiality stress paths. From an industrial point of view, it is hence possible to improve the forming of microparts using suitable stress paths. [less ▲]

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See detailDépasser la situation : de la situation-limite à la personnalité borderline. Généalogie, critique et clinique d’un concept sartrien
Cormann, Grégory ULg; Englebert, Jérôme ULg

Conference (2015, January)

Nous souhaitons interroger ici le concept sartrien de situation à partir d’une double approche historique et psychopathologique qui semble en diagnostiquer la disparition tout aussi bien conceptuelle ... [more ▼]

Nous souhaitons interroger ici le concept sartrien de situation à partir d’une double approche historique et psychopathologique qui semble en diagnostiquer la disparition tout aussi bien conceptuelle qu’existentielle : la notion de situation, organisatrice de l’ontologie phénoménologique de Sartre et pivot de son engagement, semble s’être aujourd’hui désintégrée en tant que concept (voir ses usages pseudo-conceptuels dans les domaines de la pédagogie et du management), alors que ce qu’on appelle la « condition postmoderne », telle qu’elle s’exprime dans de nouvelles symptomatologies psychopathologiques, rend apparemment caduque, face à la fragmentation des repères de l’existence, l’exigence de penser en/la situation. Nous procèderons en trois temps. Nous ferons d’abord la généalogie du concept, dont l’application à la psyché humaine et à la représentation théâtrale de celle-ci remonte, selon Leo Spitzer, à la fin du 17ème siècle. Dans cette première section, nous insisterons en particulier sur le rapport que l’élaboration du concept de situation entretient, au début du 20ème siècle, avec l’émergence de la psychopathologie notamment chez Jaspers (« situation-limite ») et chez Minkowski (nous rappellerons à cet égard le rôle de Gabriel Marcel dans le champ philosophique français de l’entre-deux-guerres). Nous serons également attentifs à la critique méthodologique que le concept de situation permet d’adresser à la métapsychologie freudienne. Sur cette base, nous reprendrons ensuite les principales étapes chez Sartre de la prise en considération de l’homme en situation et des possibilités de dépassement de cette situation. Nous envisagerons successivement l’Esquisse d’une théorie des émotions, « Questions de méthode » et L’Idiot de la famille. Il conviendra certes de rappeler comment l’existentialisme, comme le situationnisme à sa façon, a cherché, dans le sillage du marxisme, à réaliser la philosophie et du coup à transformer le concept en vécu. Mais nous montrerons aussi, à rebours, comment l’œuvre sartrienne, confrontée aux exigences conjointes du marxisme et de la psychanalyse (cf. l’analyse des pressions familiales dans le Flaubert), a dû dépasser le cadre de la magie émotionnelle au sein duquel la notion de situation s’était d’abord élaborée. Au-delà de la « situation sartrienne » – et peut-être en la prolongeant –, la critique de Deleuze des dispositifs nous servira enfin, dans un troisième temps, de point de bascule vers la condition postmoderne et la fragmentation de la situation en tant que repère d’existence. Le sujet borderline – véritable éclat de la postmodernité – nous permettra ainsi de conclure en reprenant le propos psychopathologique maturé par l’évolution conceptuelle de la situation. Nous caractériserons l’existence borderline par une fragmentation du soi corrélée à une explosion, voire à un morcellement, des espaces de vie qui répondent à la nécessité ontologique d’une « ubiquité instantanée » dénuée de présence corporelle (comme le permettent les espaces virtuels « connectés »). [less ▲]

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See detailOn the necessity and biological significance of threshold-free regulon prediction outputs
Rigali, Sébastien ULg; Nivelle, Renaud; Tocquin, Pierre ULg

in Molecular Biosystems (2015)

The in silico prediction of cis-acting elements in a genome is an efficient way to quickly obtain an overview of the biological processes controlled by a trans-acting factor, and connections between ... [more ▼]

The in silico prediction of cis-acting elements in a genome is an efficient way to quickly obtain an overview of the biological processes controlled by a trans-acting factor, and connections between regulatory networks. Several regulon prediction web tools are available, designed to identify DNA motifs predicted to be bound by transcription factors using position weight matrix-based algorithms. In this paper we expose and discuss the conflicting objectives of software creators (bioinformaticians) and software users (biologists), who aim for reliable and exhaustive prediction outputs, respectively. Software makers, concerned with providing tools that minimise the number of false positive hits, often impose a stringent threshold score for a sequence to be included in the list of the putative cis-acting sites. This rigidity eventually results in the identification of strongly reliable but largely straightforward sites, i.e. those associated with genes already anticipated to be targeted by the studied transcription factor. Importantly, this biased identification of strongly bound sequences contrasts with the biological reality where, in many circumstances, a weak DNA-protein interaction is required for the appropriate gene's expression. We show here a series of transcriptionally controlled systems involving weakly bound cis-acting elements that could never have been discovered because of the policy of preventing software users from modifying the screening parameters. Proposing only trustworthy prediction outputs thus prevents biologists from fully utilising their knowledge background and deciding to analyse statistically irrelevant hits that could nonetheless be potentially involved in subtle, unexpected, though essential cis-trans relationships. [less ▲]

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See detailA new species of Groenlandaspis Heintz, 1932 (Placodermi, Arthrodira) from the Famennian (Late Devonian) of Belgium
Olive, Sébastien ULg; Prestianni, Cyrille; Dupret, Vincent

in Journal of Vertebrate Paleontology (2015), 35(5),

A new species of the phlyctaeniid arthrodire genus Groenlandaspis from the upper Famennian of Belgium is described. The remains of Groenlandaspis potyi sp. nov. consist of dissociated thoracic armor ... [more ▼]

A new species of the phlyctaeniid arthrodire genus Groenlandaspis from the upper Famennian of Belgium is described. The remains of Groenlandaspis potyi sp. nov. consist of dissociated thoracic armor elements, but the specimen designed to be the holotype displays the median dorsal, anterior and posterior dorsolateral plates in connection. Though incomplete, the new species is characterized by an equilateral triangle-shaped median dorsal plate, a protruding posterodorsal apron of the posterior dorsolateral plate behind the overlap area for the median dorsal plate, and an overall lack of ornamentation. Groenlandaspis potyi sp. nov. constitutes the second occurrence of a Groenlandaspis species in continental Europe after the description of Groenlandaspis thorezi from upper Famennian quarries of Belgium. Another probable new species of Groenlandaspis is also described, though of unknown locality and horizon; it can however be deduced from the upper Famennian of Belgium without more precision. Together with some unpublished material of groenlandaspidids from the Famennian tetrapod-bearing locality of Strud, this material highlights the richness of the Groenlandaspididae diversity in Belgium. The discovery of Groenlandaspis potyi sp. nov. in Belgium reinforces the Famennian global distribution of this widespread genus during this period. Also, since those organisms have possibly been considered as non-marine indicators, this material is another argument pleading for close relationships between Euramerica and Gondwana around the Frasnian-Famennian boundary. [less ▲]

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See detailElsvier, Computers in Industry, Special Issue on Natural Language Processing and Text Analytics in Industry
Ittoo, Ashwin ULg; Bosh, v.d., Antal; Nguyen, Le Minh

Book published by Elsevier (2015)

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See detail"Des muets qui veulent parler". Lectures politiques, des Temps Modernes à L'Idiot de la famille
Cormann, Grégory ULg

in Bolmain, Thomas; Cormann, Grégory (Eds.) Politiques de la littérature. Bourdieu, Sartre, Foucault (2015)

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See detailRitournelles et territoires professionnels. Le cas des conseillers emploi
Orianne, Jean-François ULg

in Langage et Société (2015)

L’objectif de ce texte est d’utiliser le concept de ritournelle pour analyser la formation d’un groupe professionnel dans le champ des politiques d’emploi en Belgique : les conseillers emploi du FOREM ... [more ▼]

L’objectif de ce texte est d’utiliser le concept de ritournelle pour analyser la formation d’un groupe professionnel dans le champ des politiques d’emploi en Belgique : les conseillers emploi du FOREM. L’auteur commence par définir et opérationnaliser le concept, emprunté à Deleuze et Guattari, en suivant les apports des théories de la communication réflexive. Il esquisse brièvement le contexte politique et institutionnel au sein duquel le groupe professionnel apparaît. Ensuite, il analyse trois ritournelles professionnelles, trois procédés de territorialisation des identités professionnelles des conseillers emploi. Il précise, en conclusion, la complémentarité du concept de ritournelle avec celui de rhétorique professionnelle. [less ▲]

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See detailAlbum zutique - Dixains réalistes
Saint-Amand, Denis ULg; Grojnowski, Daniel

Book published by Garnier Flammarion (2015)

Édition de deux recueils collectifs emblématiques de la poésie française du XIXe siècle, comprenant une introduction, des notes explicatives pour chaque texte, un dossier et un dictionnaire des auteurs.

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See detailManuel. Les contrats spéciaux
Kohl, Benoît ULg; Burette, Caroline ULg; Daenen, Thomas et al

Book published by Larcier (2015)

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See detailLeibniz
Bouquiaux, Laurence ULg

in Bouaniche, Arnaud; Leclercq, Jean (Eds.) Une histoire de la philosophie (2015)

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See detailA mortar method combined with an augmented Lagrangian approach for treatment of mechanical contact problems
Cavalieri, Federico J.; Bruls, Olivier ULg; Cardona, Alberto

in Terze, Zdravko (Ed.) Multibody Dynamics: Computational Methods and Applications (2015)

This work presents a mixed penalty-duality formulation from an augmented Lagrangian approach for treating the contact inequality constraints. The augmented Lagrangian approach allows to regularize the non ... [more ▼]

This work presents a mixed penalty-duality formulation from an augmented Lagrangian approach for treating the contact inequality constraints. The augmented Lagrangian approach allows to regularize the non differentiable contact terms and gives a C1 differentiable saddle-point functional. The relative displacement of two contacting bodies is described in the framework of the Finite Element Method (FEM) using the mortar method, which gives a smooth representation of the contact forces across the bodies interface. To study the robustness and performance of the proposed algorithm, validation numerical examples with finite deformations and large slip motion are presented. [less ▲]

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See detailImpact of light and melanopsin on human cognitive brain function
Vandewalle, Gilles ULg

Conference (2015)

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See detailEnchanting gods and dolphins. A cross cultural analysis of uncanny encounters
Halloy, Arnaud; Servais, Véronique ULg

in Ethos (Berkeley, Calif.) (2015), 43(1),

Drawing on first–hand accounts of possession experiences in an Afro–Brazilian cult and Dolphin encounters at sea, we compare the two settings in order to identify the common features in people’s ... [more ▼]

Drawing on first–hand accounts of possession experiences in an Afro–Brazilian cult and Dolphin encounters at sea, we compare the two settings in order to identify the common features in people’s experiences, but also in the technologies of enchantment that make them possible. By “technology of enchantment”, we mean a space of practice, neither totally material, nor totally subjective, that supports “revelation”–like encounters with real or imagined intentional entities. Our analysis suggests that both types of experiences share at least five common traits: the presence of a prolific imagination marked by ontological and epistemological uncertainty; uncanny feelings; attentional focus on inner bodily and mental states; trance–like states; and an intentional shift from active to passive. The immersion of the individual in a sensorily organized environment (sensescape), made of distributed perceptual saliences, is found to play a central role in the merging of unusual body states with the imagination, which in turn enables the production of “new” embodied meanings belonging to enchantment. [less ▲]

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See detailLe chien des sciences de l'homme
Servais, Véronique ULg

Book published by Le bord de l'eau (2015)

L'ouvrage est divisé en deux parties. La première confronte différentes perspectives théoriques permettant de faire entrer le chien en sciences sociales. La seconde partie présente des études empiriques ... [more ▼]

L'ouvrage est divisé en deux parties. La première confronte différentes perspectives théoriques permettant de faire entrer le chien en sciences sociales. La seconde partie présente des études empiriques documentant la présence des chiens auprès des humains. [less ▲]

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See detailVers une généralisation des quartiers durables ? Présentation du référentiel d’aide à la conception et à l’évaluation développé en Wallonie et analyse prospective de douze quartiers.
Marique, Anne-Françoise ULg; Delbar, Caroline; Loiseau, Véronique ULg et al

in Urbia (2015)

Un référentiel a été développé en Wallonie, à la demande du Ministre de l’Environnement, de l’Aménagement du Territoire et de la Mobilité, pour opérationnaliser le concept de « quartier durable » en ... [more ▼]

Un référentiel a été développé en Wallonie, à la demande du Ministre de l’Environnement, de l’Aménagement du Territoire et de la Mobilité, pour opérationnaliser le concept de « quartier durable » en objectivant les critères minimum à respecter pour inscrire un quartier dans une vision transversale de développement durable. Ce référentiel constitue un cadre général qui régira les projets de quartiers durables menés en Wallonie (Belgique). Les 5 thématiques et les 25 critères qui constituent ce référentiel sont présentés. La grille de critères est ensuite appliquée à douze quartiers de façon à identifier les invariants communs aux processus de conception de ces quartiers et les freins à l’intégration des principes transversaux du développement durable dans les opérations de ce type. Si les critères relatifs aux performances énergétiques des bâtiments ont percolé dans un grand nombre de cas, la mixité des logements et leur accessibilité, la mixité sociale et la participation restent peu abordés. Le référentiel est disponible depuis début 2014 pour tous les acteurs de l’architecture et de l’urbanisme. [less ▲]

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