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See detailThéorie de la restauration et Art contemporain: une conceptualisation au service de la pratique
Verbeeck, Muriel ULg; Broers, Nico

in Restauration d'Art contemporain (in press)

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See detailCorticatus
Pfister, Max; Valenti, Gianluca ULg

in Lessico Etimologico Italiano (in press)

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See detailCarbon and Other Biogeochemical Cycles
Ciais, Philippe; Sabine, Christopher; Bala, Govindasamy et al

in Stocker, T. F.; Qin, D.; Plattner, G.-K. (Eds.) et al Climate Change 2013: The Physical Science Basis. Contribution of Working Group I to the Fifth Assessment Report of the Intergovernmental Panel on Climate Change (in press)

The present perturbations of the biogeochemical cycles of carbon dioxide (CO2), methane (CH4) and nitrous oxide (N2O), as well as their past variations (coupled to climate variations) and their projected ... [more ▼]

The present perturbations of the biogeochemical cycles of carbon dioxide (CO2), methane (CH4) and nitrous oxide (N2O), as well as their past variations (coupled to climate variations) and their projected future evolutions over the 21st century are reviewed. [less ▲]

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See detailMetabolic variability in bioprocessing : implications of microbial phenotypic heterogeneity
Delvigne, Frank ULg; Zune, Quentin ULg; Lara, Alvaro et al

in Trends in Biotechnology (in press)

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See detailConditor
Pfister, Max; Valenti, Gianluca ULg

in Lessico Etimologico Italiano (in press)

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See detailInfluence du polymorphisme nucléotidique COMT sur la mémoire de travail et son vieillissement
Manard, Marine ULg; Collette, Fabienne ULg

in Revue de Neuropsychologie, Neurosciences Cognitives et Cliniques (in press)

L’objectif de cette revue est de synthétiser les connaissances sur l’influence du polymorphisme nucléotidique Catéchol-O-Méthyltransférase (COMT) val108/158met sur la diminution des capacités de mémoire ... [more ▼]

L’objectif de cette revue est de synthétiser les connaissances sur l’influence du polymorphisme nucléotidique Catéchol-O-Méthyltransférase (COMT) val108/158met sur la diminution des capacités de mémoire de travail (et plus particulièrement de ses aspects exécutifs) associée à l’avancée en âge. Par son implication dans les processus de dégradation de la dopamine, notamment au niveau préfrontal, ce polymorphisme semble avoir un rôle central dans l’efficacité de la mise en œuvre de processus exécutifs. En effet, plusieurs études suggèrent un avantage phénotypique de l’allèle met du polymorphisme COMT lors de tâches exécutives requérant une stabilité des représentations cognitives. Etant donné les modifications cérébrales observées avec l’âge au niveau frontal, le polymorphisme COMT semble constituer une piste pertinente pour comprendre les altérations cognitives liées à l’âge. En effet, suite à la diminution d’efficacité du système dopaminergique, les personnes âgées présentent des déficits de mémoire de travail plus ou moins importants selon leur génotype pour le polymorphisme COMT. De plus, l’activité cérébrale associée à la réalisation de ces tâches va également varier en fonction de ce polymorphisme. Ces résultats soulignent l’intérêt d’intégrer les approches de génétique comportementale et de neuroimagerie génétique afin d’approfondir notre compréhension du vieillissement cognitif. [less ▲]

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See detail*Corticea
Pfister, Max; Valenti, Gianluca ULg

in Lessico Etimologico Italiano (in press)

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See detailLiving and Printing in Antwerp in the Late Fifteenth and Early Sixteenth Centuries: a Social Enquiry
Adam, Renaud ULg

in Van Bruaene, Anne-Laure; Kavaler, Ethan Matt (Eds.) Urban Perspectives on Sixteenth-Century Netherlandish Art & Culture (in press)

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See detailLes défis colossaux auxquels la santé publique va devoir faire face !
COUCKE, Philippe ULg

in Onco : Revue Multidisciplinaire d'Oncologie (in press)

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See detailImpact de l’anisotropie du milieu dans les études de profilage géographique
Trotta, Marie ULg; Deprez, Cécile; Donnay, Jean-Paul ULg

in SAGEO 2014, Grenoble 24-27 November 2014 (in press)

This communication aims at assessing the bias introduced by the use of the Euclidean distance in the context of geographic profiling analyzes. It proceeds by a comparison of road and Euclidean distances ... [more ▼]

This communication aims at assessing the bias introduced by the use of the Euclidean distance in the context of geographic profiling analyzes. It proceeds by a comparison of road and Euclidean distances of about 1 000 pairs of origin-destination (crime sites – criminal’s anchor point) from the database of the Belgian Federal Police. Comparisons are differentiated by the density of road network (rural and urban areas) and the statistical parameters of the resulting distributions are exploited in the application of the most common geographic profiling model called the distance decay model. [less ▲]

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See detailAssessing the foraging behavior of Agriotes sordidus wireworms in dual-choice olfactometers
Barsics, Fanny ULg; Fiers, Marie; Fauconnier, Marie-Laure ULg et al

in Communications in Agricultural and Applied Biological Sciences (in press)

The different steps of the foraging process of wireworms (Coleoptera: Elateridae) would be better understood if accurate and holistic information regarding the role of plant-produced chemicals ... [more ▼]

The different steps of the foraging process of wireworms (Coleoptera: Elateridae) would be better understood if accurate and holistic information regarding the role of plant-produced chemicals constituting their environment were available. Volatile organic compounds (VOC) play important roles in the interactions between plants and insects in many ecosystems, whether they take place aboveground or belowground. The roles of VOC are still relatively unknown for wireworms, and deserve attention. Here, we performed three experimentations with barley roots as baits. In the two first, we assessed the effect of chopped roots and fungus infected roots on the orientation of wireworms. In the third experiment, the larvae were confronted to both healthy and fungus infected roots. We discuss the results in terms of suitability of the olfactometers we designed for the investigation of olfaction in wireworms, and we provide suggestions to improve their use. [less ▲]

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See detailFonctionnement exécutif et réseaux cérébraux
Collette, Fabienne ULg; Salmon, Eric ULg

in Revue de Neuropsychologie, Neurosciences Cognitives et Cliniques (in press)

Depuis les observations initiales de Luria [1], la localisation cérébrale du fonctionnement exécutif a fait l’objet de nombreux travaux de recherche. Dans un premier temps, les études de patients cérébro ... [more ▼]

Depuis les observations initiales de Luria [1], la localisation cérébrale du fonctionnement exécutif a fait l’objet de nombreux travaux de recherche. Dans un premier temps, les études de patients cérébro-lésés ont mis en évidence l’implication prédominante des régions frontales. Avec l’avènement des techniques modernes d’imagerie cérébrale (tomographie à émission de positons [TEP] et imagerie par résonnance magnétique fonctionnelle [IRMf], il est toutefois apparu que le fonctionnement exécutif était sous-tendu par un réseau antéro-postérieur largement distribué. Dès ce moment, l’attention s’est portée sur le rôle exact des différentes régions impliquées lors de la réalisation d’épreuves exécutives et sur l’importance relative des régions antérieures et postérieures. Plus récemment, l’étude du fonctionnement exécutif en tant que réseau de régions fonctionnellement connectées s’est développée, et on a également commencé à s’intéresser à l’influence des aspects cérébraux structurels et des caractéristiques génétiques. Les résultats de ces travaux soulignent l’aspect interactif et fortement modulable du fonctionnement exécutif au niveau cérébral, et la nécessité de prendre en compte simultanément différents niveaux d’analyse. Nous aborderons dans cette revue ces différentes thématiques, en nous centrant sur les données issues d’études chez le sujet jeune et sain pour des raisons de concision. [less ▲]

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See detailClostridium difficile infection in elderly nursing home residents.
Rodriguez Diaz, Cristina ULg; Korsak Koulagenko, Nicolas ULg; Taminiau, Bernard ULg et al

in Anaerobe (in press), 23

Age-related changes in intestinal flora and host defences, the receipt of antibiotic treatment, and the presence of underlying diseases are some of the most common risk factors associated with Clostridium ... [more ▼]

Age-related changes in intestinal flora and host defences, the receipt of antibiotic treatment, and the presence of underlying diseases are some of the most common risk factors associated with Clostridium difficile infection. Therefore, retirement care facilities for elderly people have been pinpointed as frequent sources of contamination. There is only limited data regarding the presence and epidemiology of C. difficile in nursing homes, and this gap in the current literature emphasises the need to gain a better understanding of the situation in order to prevent the emergence of new outbreaks among this population group. [less ▲]

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See detailHeat can erase epigenetic marks of vernalization in Arabidopsis
Bouché, Frédéric ULg; Detry, Nathalie ULg; Périlleux, Claire ULg

in Plant Signaling & Behavior (in press)

Vernalization establishes a memory of winter that must be maintained for weeks or months in order to promote flowering the following spring. The stability of the vernalized state varies among plant ... [more ▼]

Vernalization establishes a memory of winter that must be maintained for weeks or months in order to promote flowering the following spring. The stability of the vernalized state varies among plant species and depends on the duration of cold exposure. In Arabidopsis thaliana, winter leads to epigenetic silencing of the floral repressor gene FLOWERING LOCUS C (FLC) and the duration of cold is measured through the dynamics of chromatin modifications during and after cold. The growing conditions encountered post-vernalization are thus critical for the maintenance of the vernalized state. We reported that high temperature leads to devernalization and, consistently, to FLC reactivation in Arabidopsis seedlings. Here we show that the repressive epigenetic mark H3K27me3 decreases at the FLC locus when vernalized seedlings are grown at 30°C, unless they were first exposed to a stabilizing period at 20°C. Ambient temperature thus controls the epigenetic memory of winter. [less ▲]

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See detailVehicle routing problems with loading constraints: State-of-the-art and future directions
Pollaris, Hanne; Braekers, Kris; Caris, An et al

in OR Spectrum (in press)

Distributors are faced with loading constraints in their route planning, e.g.,multi-dimensional packing constraints, unloading sequence constraints, stability constraints and axle weight limits. Ignoring ... [more ▼]

Distributors are faced with loading constraints in their route planning, e.g.,multi-dimensional packing constraints, unloading sequence constraints, stability constraints and axle weight limits. Ignoring these constraints impairs planning and induces last-minute changes resulting in additional costs. Developing vehicle routing models incorporating loading constraints is critical to more efficient route planning. The last couple of years has seen a huge increase of contributions to this field of research with almost 60 % of these being published after 2009. Our contribution is twofold. First, we overview the recent developments in the literature on all vehicle types in which loading constraints play a key role (trucks, airplanes, ships, and automated guided vehicles), using a state-of-the-art classification scheme to identify the loading constraints considered in each article. Second, we identify research gaps and opportunities for future research. [less ▲]

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See detailCommentary on recent therapeutic guidelines for osteoarthritis
Cutolo, M; Berenbaum, F; Hochberg, M et al

in Seminars in Arthritis & Rheumatism (in press)

Background Despite availability of international evidence-based guidelines for osteoarthritis (OA) management, agreement on the different treatment modalities is lacking. Method A symposium of European ... [more ▼]

Background Despite availability of international evidence-based guidelines for osteoarthritis (OA) management, agreement on the different treatment modalities is lacking. Method A symposium of European and US OA experts was held within the framework of the Annual European Congress of Rheumatology to discuss and compare guidelines and recommendations for the treatment of knee OA and to reach a consensus for management, particularly for areas in which there is no clear consensus: non-pharmacological therapy; efficacy and safety of analgesics and non-steroidal anti-inflammatory drugs (NSAIDs); intra-articular (i.a.) hyaluronates (HA); and the role of chondroitin sulfate (CS) and/or glucosamine sulfate (GS). Results All guidelines reviewed agree that knee OA is a progressive disease of the joint whose management requires non-pharmacological and pharmacological approaches. Discrepancies between guidelines are few and mostly reflect heterogeneity of expert panels involved, geographical differences in the availability of pharmacotherapies, and heterogeneity of studies included. Panels chosen for guideline development should include experts with real clinical experience in drug use and patient management. Implementation of agreed guidelines can be thwarted by drug availability and reimbursement plans, resulting in optimal OA treatment being jeopardized, HA and symptomatic slow-acting drugs for osteoarthritis (SySADOAs) being clear examples of drugs whose availability and prescription can greatly vary geographically. In addition, primary care providers, often responsible for OA management (at least in early disease), may not adhere to clinical care guidelines, particularly for non-pharmacological OA treatment. Conclusion Harmonization of the recommendations for knee OA treatment is challenging but feasible, as shown by the step-by-step therapeutic algorithm developed by European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). More easily disseminated and implemented guidance for OA treatment in the primary care setting is key to improved management of OA. [less ▲]

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See detailRetour au sport après plastie du ligament croisé antérieur : critères utilisés dans les cubs professionnels de football
Delvaux, François ULg; Rochcongar, P; Bruyère, Olivier ULg et al

in Science et Sports (in press)

Résumé Objectifs Analyser la démarche suivie par les médecins de clubs professionnels de football lorsqu’ils décident, en pratique quotidienne, d’autoriser le retour compétitif après plastie du ligament ... [more ▼]

Résumé Objectifs Analyser la démarche suivie par les médecins de clubs professionnels de football lorsqu’ils décident, en pratique quotidienne, d’autoriser le retour compétitif après plastie du ligament croisé antérieur chez un footballeur. Matériels et méthodes Trente-sept médecins responsables de clubs professionnels de football français et belges (Ligue 1, n = 15 ; Ligue 2, n = 14 ; Division 1 belge, n = 8) ont rempli un questionnaire à choix multiple concernant : (1) les critères utilisés afin de déterminer si un joueur est apte à reprendre la compétition après plastie du ligament croisé antérieur ; (2) l’importance relative de chacun de ces critères ; (3) le rôle éventuel d’intervenants spécifiques (kinésithérapeute…) dans cette décision. Résultats Plus de 80 % des médecins interrogés ont déclaré utiliser au moins huit critères (sur 17 proposés) afin d’évaluer la capacité d’un footballeur à reprendre la compétition après plastie du ligament croisé antérieur. Les trois critères considérés comme les plus déterminants étaient, par ordre d’importance : la stabilité dynamique du genou lors d’un exercice spécifique au football, la force musculaire et la récupération complète ou quasi complète d’amplitudes articulaires de flexion et d’extension de genou. Pour certains de ces critères (notamment la force musculaire), nous constatons cependant un manque de consensus sur les modalités pratiques d’évaluation, sur les paramètres ainsi que sur les valeurs-limites tolérées afin de garantir un retour sur terrain sécurisé. La prise en compte de l’avis du kinésithérapeute et du préparateur physique par une très nette majorité de médecins souligne l’importance d’un travail pluridisciplinaire. Conclusion L’utilisation de différents critères objectifs afin d’autoriser le retour compétitif après plastie du ligament croisé antérieur semble être une réalité dans le football professionnel. Des études supplémentaires devraient cependant contribuer à préciser les modalités des épreuves ainsi que des valeurs-seuils. ________________________________________ Summary Purpose To analyze how sport physicians decide, in their daily practice, when a professional soccer player with a reconstructed anterior cruciate ligament is able to get back to competitive activities. Materials and methods Thirty-seven physicians for professional French and Belgian soccer teams filled in a specific questionnaire dedicated to: (1) return-to-play criteria after anterior cruciate reconstruction; (2) the importance they assigned to each of these criteria in the return-to-play decision; (3) the potential role of professionals, such as physiotherapists or physical coaches in this decision. Results More than 80% of the respondents declared to use at least eight criteria in order to assess the player's ability to return to competitive soccer after anterior cruciate ligament reconstruction. The most important ones were (in order of importance): dynamic knee stability during a specific soccer exercise, muscle strength performance and normalization of knee flexion and extension ranges of motion. For most of these criteria (notably muscle strength), there was a lack of consensus about the choice of assessment parameters and the limit values allowing physicians to authorize or forbid the return-to-competition. A large majority of participants stated to take into consideration advices from physiotherapists or physical coaches for the return-to-play decision. Conclusion Sport physicians of professional soccer teams use relevant criteria to assess players’ ability to return to full sport after anterior cruciate ligament reconstruction. Further studies are required to determine the choice of assessment parameters and the limit values to assist physicians in return-to-play decisions. [less ▲]

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