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See detailCharacterization of GPR101 transcripts structure, expression and signaling
Trivellin, G; Bjelobaba, I; Daly, Adrian ULg et al

in Abstract book - Keystone Symposia on GPCRs (2016, February)

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See detailDoing better in more complex patients: leading the way for QUIP.
Osnabrugge, Ruben L.; Kappetein, A. Pieter; Head, Stuart J. et al

in European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery (2016), 49(2), 397-8

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See detailDynamic Distribution and Interaction of the Arabidopsis SRSF1 Subfamily Splicing Factors
Stankovic, Nancy ULg; Schloesser, Marie ULg; Joris, Marine ULg et al

in Plant Physiology (2016), 170

Serine/Arginine-rich (SR) proteins are essential nucleus-localized splicing factors. Our prior studies showed that Arabidopsis RSZ22, a homolog of the human SRSF7 SR factor, exits the nucleus through two ... [more ▼]

Serine/Arginine-rich (SR) proteins are essential nucleus-localized splicing factors. Our prior studies showed that Arabidopsis RSZ22, a homolog of the human SRSF7 SR factor, exits the nucleus through two pathways, either dependent or independent on the XPO1 receptor. Here, we examined the expression profiles and shuttling dynamics of the Arabidopsis SRSF1 subfamily (SR30, SR34, SR34a and SR34b) under control of their endogenous promoter in Arabidopsis and in transient expression assay. Due to its rapid nucleocytoplasmic shuttling and high expression level in transient assay, we analysed the multiple determinants that regulate the localisation and shuttling dynamics of SR34. By site-directed mutagenesis of SR34 RNA-binding sequences and RS domain, we further show that functional RRM1 or RRM2 are dispensable for the exclusive protein nuclear localization and speckle-like distribution. However, mutations of both RRMs induced aggregation of the protein whereas mutation in the RS domain decreased the stability of the protein and suppressed its nuclear accumulation. Furthermore, the RNA-binding motif mutants are defective for their export through the XPO1 (CRM1/Exportin-1) receptor pathway, but retain nucleocytoplasmic mobility. We performed a yeast two hybrid screen with SR34 as bait and discovered SR45 as a new interactor. SR45 is an unusual SR splicing factor bearing two RS domains. These interactions were confirmed in planta by FLIM-FRET and BiFC and the roles of SR34 domains in protein-protein interactions were further studied. Altogether, our report extends our understanding of shuttling dynamics of Arabidopsis SR splicing factors [less ▲]

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See detailCommuniquer pour mieux gérer les ressources naturelles, cas pilote du bassin versant de la rivière Lukaya.
Jacmain, Céline; Rosillon, Francis ULg

in Elongo, V.L.; Wildi, Walter; Onaotsho, K. (Eds.) et al Actes du séminaire interdisciplinaire et interuniversitaire : Communication environnementale dans les pays en développement : enjeux, modèles, applications. (2016, February)

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See detailDiagnosis of sickle cell disease by innovative PCR without DNA extraction
DETEMMERMAN, Liselot; BOEMER, François ULg; OLIVIER, Sabine

Poster (2016, February)

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See detailThe English Experience of Soft Densification (Les expériences anglaises en matière de densification douce). Phase II Draft Report
Bibby, Peter; Dunning, Richard; Ferrari, Ed et al

Report (2016)

This report is the second phase of research into the English Experience of Soft Densification and builds upon the quantitative data analysis undertaken in phase I. Adopting an intensive qualitative case ... [more ▼]

This report is the second phase of research into the English Experience of Soft Densification and builds upon the quantitative data analysis undertaken in phase I. Adopting an intensive qualitative case study approach two local authorities, the London Borough of Ealing and Bristol City Council, are considered in detail. Ealing represents a suburban area that experienced concurrently significant soft densification and de-conversion of existing stock in the period 2001 to 2011, whilst Bristol over the same period experienced a high level of housing growth. [less ▲]

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See detailMesh Management Methods in Finite Element Simulations of Orthodontic Tooth Movement
Mengoni, Marlène ULg; Ponthot, Jean-Philippe ULg; Boman, Romain ULg

in Medical Engineering & Physics (2016), 38(2), 140-147

In finite element simulations of orthodontic tooth movement, one of the challenges is to represent long term tooth movement. Large deformation of the periodontal ligament and large tooth displacment due ... [more ▼]

In finite element simulations of orthodontic tooth movement, one of the challenges is to represent long term tooth movement. Large deformation of the periodontal ligament and large tooth displacment due to bone remodelling lead to large distortions of the finite element mesh when a Lagrangian formalism is used. We propose in this work to use an Arbitrary Lagrangian Eulerian (ALE) formalism to delay remeshing operations. A large tooth displacement is obtained including effect of remodelling without the need of remeshing steps but keeping a good-quality mesh. Very large deformations in soft tissues such as the periodontal ligament is obtained using a combination of the ALE formalism used continuously and a remeshing algorithm used when needed. This work demonstrates that the ALE formalism is a very efficient way to delay remeshing operations. [less ▲]

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See detailIs Darwin's 'Abominable Mystery' still a mystery today?
Cascales-Miñana, Borja ULg; Cleal, Chris J.; Gerrienne, Philippe ULg

in Cretaceous Research (2016), 61

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See detailIntroduction au droit - partim droit public (HEC) - plan général du cours 2015-16
Bouhon, Frédéric ULg

Learning material (2016)

Ce document présente le plan général du partim 'droit public' du cours d'Introduction au droit destiné aux étudiants inscrits en bachelier à HEC-Ulg.

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See detailDroit parlementaire et électoral - Plan général du cours 2015-16
Bouhon, Frédéric ULg

Learning material (2016)

Ce document présente le plan général du cours de Droit parlementaire et électoral, destiné à des étudiants de Master en droit et de Master en sciences politiques à l'ULg.

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See detailOverview of Superhydrophilic, Photocatalytic and Anticorrosive Properties of TiO2 Thin Films Doped with Multi-walled Carbon Nanotubes and Deposited on 316L Stainless Steel
Léonard, Géraldine ULg; Remy, Simon; Heinrichs, Benoît ULg

in Materials Today: Proceedings (2016, February), 3(2), 434-438

TiO2 films with MWCNTs are produced for anticorrosive applications to increase the lifetime of steel materials. TiO2 has two additional properties, photoactivity and superhydrophilicity. Two TiO2 samples ... [more ▼]

TiO2 films with MWCNTs are produced for anticorrosive applications to increase the lifetime of steel materials. TiO2 has two additional properties, photoactivity and superhydrophilicity. Two TiO2 samples, synthesized in aqueous or alcoholic media, have been doped with MWCNTs. The material which best combines anticorrosive, superhydrophilic and photocatalytic properties, is the one produced in aqueous medium (Aq-TiO2-CNT). Doping with MWCNTs increases the photodegradation of p-nitrophenol from 18% to 50%. MWCNTs allow to reduce the corrosion current and the corrosion potential. The good superhydrophilicity of TiO2 is kept on stainless steel with a contact angle after illumination around 5°. [less ▲]

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See detailAnalysis of the Structure and Function of FOX-4 Cephamycinase
Lefurgy, S.T.; Malashkevich, V.N.; Aguilan, J.T. et al

in Antimicrobial Agents and Chemotherapy (2016), 60(2), 717-728

Class C β-lactamases poorly hydrolyze cephamycins (e.g., cefoxitin, cefotetan, and moxalactam). In the past 2 decades, a new family of plasmid-based AmpC β-lactamases conferring resistance to cefoxitin ... [more ▼]

Class C β-lactamases poorly hydrolyze cephamycins (e.g., cefoxitin, cefotetan, and moxalactam). In the past 2 decades, a new family of plasmid-based AmpC β-lactamases conferring resistance to cefoxitin, the FOX family, has grown to include nine unique members descended from the Aeromonas caviae chromosomal AmpC. To understand the basis for the unique cephamycinase activity in the FOX family, we determined the first X-ray crystal structures of FOX-4, apo enzyme and the acyl-enzyme with its namesake compound, cefoxitin, using the Y150F deacylation-deficient variant. Notably, recombinant expression of N-terminally tagged FOX-4 also yielded an inactive adenylylated enzyme form not previously observed in β-lactamases. The posttranslational modification (PTM), which occurs on the active site Ser64, would not seem to provide a selective advantage, yet might present an opportunity for the design of novel antibacterial drugs. Substantial ligand-induced changes in the enzyme are seen in the acyl-enzyme complex, particularly the R2 loop and helix H10 (P289 to N297), with movement of F293 by 10.3 Å. Taken together, this study provides the first picture of this highly proficient class C cephamycinase, uncovers a novel PTM, and suggests a possible cephamycin resistance mechanism involving repositioning of the substrate due to the presence of S153P, N289P, and N346I substitutions in the ligand binding pocket. [less ▲]

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See detailTEST-RETEST RELIABILITY OF TWO CLINICAL TESTS FOR THE ASSESSMENT OF HIP ABDUCTOR ENDURANCE IN HEALTHY FEMALES
Van Cant, Joachim; Dumont, Gregory; Pitance, Laurent et al

in The International Journal of Sports Physical Therapy (2016), 11(1), 24-33

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See detailLes conseils scientifiques des institutions de conservation de la nature et de développement durable. Une approche par le vécu d’instances entre science et politique.
arpin, isabelle; cosson, arnaud; Denayer, Dorothée ULg et al

in SCIENCES ET BIODIVERSITÉ. Acteurs, enjeux, temporalités (2016)

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See detail50 ans d'exploration de la planète Mars
Stiepen, Arnaud ULg

Conference given outside the academic context (2016)

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See detailLa pauvreté infantile et juvénile en Fédération Wallonie-Bruxelles
Guio, Anne-Catherine; Baye, Ariane ULg

Report (2016)

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See detailCrossoads février 2016 - chaque mercredi 18h-20h
Sacré, Robert ULg

Diverse speeche and writing (2016)

Magazine sonore du blues et des musiques américaines ( séquences R&B, Soul, Zydeco, Gospel,jazz, etc...)

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