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See detailModulation of NMDA receptor mediated excitatory synaptic currents in dopamine neurons of the substantia nigra
Destreel, Geoffrey ULg; Seutin, Vincent ULg; Engel, Dominique ULg

Poster (2017, May 17)

Dopamine (DA) neurons of the substantia nigra pars compacta (SNc) exhibit two main firing modes, spontaneous single action potential (AP) firing and bursting. The amount of DA released by these neurons in ... [more ▼]

Dopamine (DA) neurons of the substantia nigra pars compacta (SNc) exhibit two main firing modes, spontaneous single action potential (AP) firing and bursting. The amount of DA released by these neurons in target areas depends on the presynaptic AP firing pattern and is essential to modulate several aspects of behavior such as the control of movement. Bursting activity is mediated by excitatory afferents and specifically by the activation of NMDA receptors (NMDARs). However, the level of activation of NMDARs at these synapses during spontaneous synaptic activity is unknown. We assessed the occupancy of the glycine binding sites of the NMDAR by testing the effects of coagonists and by blocking the uptake of glycine on spontaneous excitatory postsynaptic currents (sEPSCs) in DA neurons of the SNc. Parasagittal midbrain slices (300 – 350 µm thickness) were cut from the brains 16- to 26- days old Wistar rats using a vibratome. Whole-cell recordings were made using warm (~35C°) standard artificial cerebrospinal fluid. sEPSCs were pharmacologically isolated and recorded at +40 and -70 mV. A large NMDAR-sEPSC component was present at +40 mV as revealed by the application of 50 µM D-AP5 (n=8, P < 0.001). At -70 mV, D-AP5 had no effect on the EPSC, as expected (n=7, P = 0.52). The mean amplitude of the average NMDAR sEPSC measured at +40 mV increased significantly from 8.6 ± 0.8 pA in control conditions to 10.9 ± 1.0 pA during bath application of 300 μM glycine (n=10, P < 0.001). We also investigated the effect of D-serine, the other coagonist at the NMDAR glycine site. The mean NMDAR EPSC amplitude measured at +40 mV showed a tendency toward larger values, from 6.8 ± 0.8 pA in control conditions to 8.8 ± 1.1 pA in the presence of 100 µM D-serine (n=4). Blockade of the glycine transporter-1 (GlyT1) significantly increased the mean amplitude of NMDAR sEPSCs measured at +40 mV from 7.1 ± 0.5 pA in control conditions to 10.5 ± 0.8 pA in the presence of 5 μM NFPS (n=8, P < 0.001). At -70 mV, NFPS had no effect on the AMPAR-sEPSC component, as expected (n=8, P = 0.23). In conclusion, our results indicate that the NMDAR glycine sites are not saturated by glycine and D-serine during sEPSCs in control conditions. [less ▲]

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See detailAharonov-Bohm oscillations of bosonic matter-wave beams in the presence of disorder and interaction
Chrétien, Renaud ULg; Dujardin, Julien; Petitjean, Cyril ULg et al

Poster (2017, May 17)

We study the one-dimensional (1D) transport properties of an ultracold gas of Bose-Einstein condensed atoms through Aharonov-Bohm (AB) rings. Our system consists of a Bose-Einstein condensate (BEC) that ... [more ▼]

We study the one-dimensional (1D) transport properties of an ultracold gas of Bose-Einstein condensed atoms through Aharonov-Bohm (AB) rings. Our system consists of a Bose-Einstein condensate (BEC) that is outcoupled from a magnetic trap into a 1D waveguide which is made of two semi-infinite leads that join a ring geometry exposed to a synthetic magnetic flux φ. We specifically investigate the effects both of a disorder potential and of a small atom-atom contact interaction strength on the AB oscillations. The main numerical tools that we use for this purpose are a mean-field Gross-Pitaevskii (GP) description and the truncated Wigner (tW) method. We find that a correlated disorder suppress the AB oscillations leaving thereby place to weaker amplitude, half period oscillations on transmission, namely the Aronov-Al’tshuler-Spivak (AAS) oscillations. The competition between disorder and interaction leads to a flip of the transmission at the AB flux φ = π. This flip could be a possible preliminary signature of an inversion of the coherent backscattering (CBS) peak. Our study paves the way to an analytical description of the inversion of that peak. [less ▲]

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See detailNON-INVASIVE ANALYSIS OF POTENTIALLY DYSREGULATED MIRNAS IN ENDOMETRIOSIS
Munaut, Carine ULg; Emonard, Violaine; TIMMERMANS, Marie ULg et al

Conference (2017, May 17)

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See detailOrganiser et animer des séances de cas pratiques en droit
Biquet, Christine ULg

Learning material (2017)

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See detailDefining thermal comfort boundaries for heating and cooling demand estimation in Iran's urban settlements
Roshan, GhR.; Farrokhzad, M.; Attia, Shady ULg

in Building & Environment (2017), 121

Iran has diverse climate variability, comfort boundaries for each geographic region must be defined in order to present current architectural design recommendations and proper mechanical systems design to ... [more ▼]

Iran has diverse climate variability, comfort boundaries for each geographic region must be defined in order to present current architectural design recommendations and proper mechanical systems design to meet building's heating and cooling energy demand. Therefore, two components of the temperature and relative humidity of 148 stations with the longest common statistical period of twenty years (1994–2014), which have been in daily scale were selected to calibrate and redefine the thermal boundary conditions in Iran. Givoni chart was used to define and visualize the bioclimatic conditions in buildings. The results of this study indicate that only 18% of the 148 stations days, falls in the thermal comfort bioclimatic conditions. After calibration of the base comfort temperature, we found that the upper threshold of this component varies from at least 22.62 °C for Ardebil to 25.94 °C for Dorudzan station and the low threshold of this component belongs to Ardebil with at least 20.13 °C up to its maximum value with 22 °C which belongs to Dorudzan. Spatial distribution of cooling and heating days show that their maximum threshold has been for cores in Northeastern half of Iran, Iran's Western half and some Central parts of Iran and the minimum threshold of these two components belongs to the beaches of north and south of the country. The findings present updated thermal comfort boundaries that can be used by architects, engineers and policy makers to achieve, in turn, more energy efficient homes and high quality indoor and outdoor living environments. [less ▲]

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See detailFirst Characterisation of Volatile Organic Compounds Emitted by Banana Plants
Berhal, Chadi ULg; De Clerck, Caroline ULg; Fauconnier, Marie-Laure ULg et al

in Scientific Reports (2017)

Banana (Musa sp.) ranks fourth in term of worldwide fruit production, and has economical and nutritional key values. The Cavendish cultivars correspond to more than 90% of the production of dessert banana ... [more ▼]

Banana (Musa sp.) ranks fourth in term of worldwide fruit production, and has economical and nutritional key values. The Cavendish cultivars correspond to more than 90% of the production of dessert banana while cooking cultivars are widely consumed locally around the banana belt production area. Many plants, if not all, produce Volatile Organic Compounds (VOCs) as a means of communication with their environment. Although flower and fruit VOCs have been studied for banana, the VOCs produced by the plant have never been identified despite their importance in plant health and development. A volatile collection methodology was optimized to improve the sensitivity and reproducibility of VOCs analysis from banana plants. We have identified 11 VOCs for the Cavendish, mainly (E,E)-α-farnesene (87.90 ± 11.28 ng/μl), methyl salicylate (33.82 ± 14.29) and 6-methyl-5-hepten-2-one (29.60 ± 11.66), and 14 VOCs for the Pacific Plantain cultivar, mainly (Z,E)-α-farnesene (799.64 ± 503.15), (E,E)-α-farnesene (571.24 ± 381.70) and (E) β ocimene (241.76 ± 158.49). This exploratory study paves the way for an in-depth characterisation of VOCs emitted by Musa plants. [less ▲]

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See detailFish introductions, newt decline and paedomorph extinction
Denoël, Mathieu ULg

Scientific conference (2017, May 16)

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See detailEvoluer avec les étudiants
Younes, Nathalie; Detroz, Pascal ULg

Scientific conference (2017, May 16)

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See detailDIGITAL INVESTIGATIONS OF AN ARCHAEOLOGICAL SMART POINT CLOUD: A REAL TIME WEB-BASED PLATFORM TO MANAGE THE VISUALISATION OF SEMANTICAL QUERIES
Poux, Florent ULg; Neuville, Romain ULg; Hallot, Pierre ULg et al

in Conservation of Cultural Heritage in the Digital Era (2017, May 16)

While virtual copies of the real world tend to be created faster than ever through point clouds and derivatives, their working proficiency by all professionals’ demands adapted tools to facilitate ... [more ▼]

While virtual copies of the real world tend to be created faster than ever through point clouds and derivatives, their working proficiency by all professionals’ demands adapted tools to facilitate knowledge dissemination. Digital investigations are changing the way cultural heritage researchers, archaeologists, and curators work and collaborate to progressively aggregate expertise through one common platform. In this paper, we present a web application in a WebGL framework accessible on any HTML5-compatible browser. It allows real time point cloud exploration of the mosaics in the Oratory of Germigny-des-Prés, and emphasises the ease of use as well as performances. Our reasoning engine is constructed over a semantically rich point cloud data structure, where metadata has been injected a priori. We developed a tool that directly allows semantic extraction and visualisation of pertinent information for the end users. It leads to efficient communication between actors by proposing optimal 3D viewpoints as a basis on which interactions can grow. [less ▲]

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See detailMatières premières et environnement - Défis pour le développement des compétences en Afrique Centrale
Pirard, Eric ULg

Scientific conference (2017, May 16)

Historique des programmes de formation que l'ULiège a mis en place à destination de l'Afrique dans le domaine des ressources minérales. Obstacles rencontrés à la mise en oeuvre de certains projets et ... [more ▼]

Historique des programmes de formation que l'ULiège a mis en place à destination de l'Afrique dans le domaine des ressources minérales. Obstacles rencontrés à la mise en oeuvre de certains projets et défis qui nous attendent. Perception des stratégies propres à l'espace francophone dans une dynamique de numérisation et de mondialisation tous azimuts. [less ▲]

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See detailA la recherche du poisson diplomatique: connaître les pollutions du Golfe de Fos avec les congres (France)
Melard, François ULg; Gramaglia, Christelle

Scientific conference (2017, May 16)

Présentation des premiers résultats de recherche sur l'usage d'espèce de poisson (le Congres) comme bioindicateur par un institut de recherche français (Institut écocitoyen pour la connaissances des ... [more ▼]

Présentation des premiers résultats de recherche sur l'usage d'espèce de poisson (le Congres) comme bioindicateur par un institut de recherche français (Institut écocitoyen pour la connaissances des pollutions dans le golf de Fos (sud de la France). Ce monitoring est faite en collaboration avec des citoyens dans la philosophie participative qui anime l'institut. [less ▲]

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See detailUse of a bio-based binder in the building sector
Gerbinet, Saïcha ULg; Briard, Vincent; Pigeolet, Jean-Pierre et al

Poster (2017, May 15)

A binder is a material or a substance that holds materials together, like a glue. In the building sector, binders have several applications: they can be used in producing wood panels such as MDF to paste ... [more ▼]

A binder is a material or a substance that holds materials together, like a glue. In the building sector, binders have several applications: they can be used in producing wood panels such as MDF to paste together the wood particles and give the panels their stabil-ity. They are also used in insulation materials, such as glass wool or stone wool to bind the fibers together. Traditional binders are mostly fossil-based (phenol-formaldehyde, urea-formaldehyde, etc.), and previous Life Cycle Assessments (LCA) [1-3] show that these binders, even if they are a minor component on a mass basis, can have a major contribution to the environmental impact of the material, especially in wood panels. In addition, the use of these binders has raised some sanitary questions, especially con-cerning indoor air quality. Therefore alternative binders are being investigated, namely bio-based binders. In this presentation, we focus on the ECOSE binder, developed by Knauf Insulation, a global building insulation manufacturer. It has the particularity of being based on plant starch and it is currently used in glass wool products, while other applications are being developed. We underline that using biomass as raw materials instead of fossil-based ma-terials could have several benefits on the environment, especially fossil resources deple-tion and CO2 emissions, but that this is not necessarily the case for all environmental as-pects, for instance land use, even if only the direct land use is included in this study. The presentation will first underline the differences in term of environmental impact be-tween the traditional binder and ECOSE applied in glass mineral wool. Indeed, a compar-ison on a mass basis is not totally relevant: two binders can have different application conditions; therefore, we can only compare them at the application level. But the main focus of the presentation will be on the hypothesis made in the modeling of the biomass part and their influence on the results. For example, the influence of the use of bio-based raw materials instead of traditional ones will be studied, but also the influence of the dis-tance between farm and factory where the starch is produced. The use of local data will be compared with the use of databases. All these results will highlight the difficulties in studying bio-based products and to compare them with fossil-based ones. The use of LCA and a complete analysis of the results are essential to better understand the chal-lenges related to binder technology modification. ________________________________________ 1. Rivela, B., et al., Life cycle inventory of particleboard: A case study in the wood sector. International Journal of Life Cycle Assessment, 2006. 11(2): p. 106-113. 2. Wilson, J.B., Particleboard: A Life-Cycle Inventory of Manufacturing Panels from Resource through Product, in CORRIM: Phase II Final Report. 2008, Department of Wood Science and Engineering, Oregon State University. 3. Silva, D.A.L., et al., Environmental performance assessment of the melamine-urea-formaldehy (MUF) resin manufacture: a case study in Brazil. Journal of Cleaner Production, 2015. 96. [less ▲]

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See detailEffects of isolated versus combined learning enactments in an online course
Verpoorten, Dominique ULg; Westera, Wim; Specht, Marcus

in International Journal of Technology Enhanced Learning (2017), 9(2), 169-185

In a controlled experiment on the effects of frequent and local digital annotations, 137 volunteers covered an online course under three possible conditions: no/free/question-based digital annotations ... [more ▼]

In a controlled experiment on the effects of frequent and local digital annotations, 137 volunteers covered an online course under three possible conditions: no/free/question-based digital annotations. Results show no difference in performance between groups when annotation behaviour is considered in isolation. However, analyses conducted within treatments provide indications of a positive impact on performance when annotation rates are taken into consideration, and coupled with other enactments tracked in the course. Combined in engagement profiles (Learning DNAs), these enactments suggest that what makes active learning efficient might be an ongoing crisscrossing between a firstorder learning activity (the study of the course) and a series of second order activities, such as making notes. Students who manage to coordinate these activities at a higher rate perform better. This observation opens a line of reasoning about what determines the quality of a mental engagement in a learning task, in terms of balance and rotation of cognitive and metacognitive operations. [less ▲]

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See detailLe manuel de grammaire latine de Dosithée : quelle méthode d'apprentissge ?
Rochette, Bruno ULg

Conference (2017, May 15)

Contrairement aux autres manuels de grammaire latine destinés aux hellénophones, comme ceux de Charisius, Diomède et Priscien qui travaillent dans la pars Orientis pour des hellénophones, l’Ars grammatica ... [more ▼]

Contrairement aux autres manuels de grammaire latine destinés aux hellénophones, comme ceux de Charisius, Diomède et Priscien qui travaillent dans la pars Orientis pour des hellénophones, l’Ars grammatica de Dosithée est accompagnée d’une traduction grecque. La présence de cette traduction, qui ne concerne toutefois pas toute la grammaire, mais seulement environ la moitié du texte, singularise ce manuel dans la tradition des artes, même si nous ne pouvons exclure que d’autres traités grammaticaux du même type n’aient pas été accompagnés d’une traduction grecque que nous n’aurions pas conservée. Quoi qu’il en soit, le statut de cette traduction est assez difficile à établir. Essentiellement deux questions se posent à son sujet : quel est son auteur, est-ce Dosithée lui-même ou un utilisateur plus tardif (éventuellement dans le monde occidental), et à quoi sert-elle ? Il apparaît clairement que le grec doit aider à la compréhension du latin, non le remplacer. La traduction grecque n’a donc pas une vocation à l’autonomie. Elle n’a de sens qu’en relation avec le latin. La traduction semble se réduire au fur et à mesure que l’on avance dans la grammaire. Il semble que Dosithée attende de l’utilisateur de la grammaire qu’il ait de moins en moins besoin d’aide à mesure qu’il progresse dans l’apprentissage. J’analyse la nature du grec de Dosithée en vue de mieux comprendre la méthode d’apprentissage mise en œuvre dans ce manuel. Bibliographie Bonnet G., Dosithée. Grammaire latine, Paris, CUF, 2005. --, La version grecque de l’Ars de Dosithée, dans L. Basset-Fr. Biville-B. Colombat-P. Swiggers-A. Wouters (éds), Bilinguisme et terminologie grammaticale gréco-latine, Leuven-Paris-Dudley, 2007, p. 191-199. Dickey E., The Authorship of the Greek Version of Dositheus’ Grammar and What it Tells Us about the Grammar’s Original Use, dans R. Ferri-A. Zago (eds), The Latin of the Grammarians. Reflections about Language in the Roman World, Turnhout, 2016, p. 205-235. --, Learning Latin. The Ancient Way. Latin Textbooks from the Ancient World, Cambridge, 2016. Lenoble M. – Swiggers P. – Wouters P., L’enseignement grammatical entre grec et latin : le manuel de Dosithée, P. Desmet-L. Jooken-P. Schmitter-P. Swiggers (eds), The History of Linguistic and Grammatical Praxis. Proceedings of the XIth International Colloquium of the Studienkreis « Geschichte der Sprachwissenschaft » (Leuven, 2nd – 4th July, 1998), Leuven-Paris-Sterling, 2000, p. 3-22. Reichamnn V., Römische Literatur in griechischer Übersetzung, Leipzig, 1943. J. Tolkiehn J., Dosithei Ars Grammatica, Leipzig, 1913. [less ▲]

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See detailEtude descriptive et relationnelle des facteurs de risque d’infécondité et d’infertilité des vaches laitières au sud Viet Nam
Nguyen, Kien Cuong ULg

Doctoral thesis (2017)

Increasing milk production is a key issue for Vietnam. Improving milk production involves controlling direct or indirect factors responsible for this. These factors are genetics, feed, environment, and ... [more ▼]

Increasing milk production is a key issue for Vietnam. Improving milk production involves controlling direct or indirect factors responsible for this. These factors are genetics, feed, environment, and reproductive performance. The identification and control of individual or collective factors responsible for reproductive performance is therefore an important step in improving milk production. The general objective of our study is to describe the milk and reproductive performances of dairy smallholding in Vietnam and to analyze the effects of risk factors on reproductive performance. The specific objectives are:(1) to describe the physiological and pathological characteristics of genital tract of culled dairy cows in dairy smallholding; (2) to specify the fecundity and fertility of heifers and dairy cows of small dairy farms; (3) to identify the postpartum (PP) reproductive disorders of cows in dairy smallholders (4) to analyze the effects of individual and environmental risk factors on the reproductive performance of heifers and cows; and (5) to analyze the risk factors for the postpartum (PP) reproductive disorders of cows. The first work of our study was conducted from February to August 2012 on 507 culled crossbred Holstein Friesian (HF) x Lai Sind (LS) dairy cows at two slaughterhouses in HCMC. Age and body condition score (BCS) of cows were determined prior to slaughter. A visual examination of vulva region was also performed to identify the presence of eventual discharges. Then, vaginoscopic examination was performed to determine the presence of discharges and pneumovagina or even urovagina. After slaughter, the uterus was incised to examine the contents. Oviducts were observed to identify abnormalities. The ovaries were collected to evaluate eventual structures (number and diameter of follicles, corpus luteum - CL and cysts) using an ultrasound (KX5200, 6.5 MHz linear probe). The results of this study revealed some important pathological characteristics of examined cows. Nearly half (44.4%) of examined cows had a BCS lower than 2.5. The prevalence of pneumovagina and urovagina was 33.1% and 14.7%, respectively; age and BCS have had a significant effect on the prevalence of these pathologies. The frequencies of vaginal discharges and abnormal uterine contents were 12.1% and 5.4%, respectively. 226 out of 507 examined cows (44.6%) were in anœstrus. The frequencies of functional pathological anœstrus, cystic, pyometral and gestation were 37.3%, 2.0%, 0.4% and 4.9%, respectively. Type 0 and I anœstrus have been more often observed in cows with low BCS and in cows aged less than 6 years. The results of the first work reinforced us in the need to set up specific monitoring of small dairy farms at HCMC. The total of 232 heifers and 244 cows (261 lactations) of 35 small farms in Cu Chi district, HCMC were observed during the years 2013 and 2014. The animals are kept permanently indoors. Their diet consists of fodder (Pennisetum purpureum or natural grass and rice straw), concentrates and by-products (spent grain and cassava waste). Each farm was monitored monthly for reproduction of heifers and cows by transrectal palpation, ultrasound (KX5200, 6.5 MHz linear probe) and vaginoscopy. Reproductive data (dates and type of calving, calf sex, complications, results of clinical examinations, date of heat, date of insemination), milk production (daily average milk yield per cow), BCS and weight of heifers were updated at each visit. The reproductive performance was assessed by fecundity and fertility parameters. The fecundity of heifers and cows was calculated by (1) birth to conception interval (heifers) (or age at conception – AC) or calving to conception interval (cows) (or days open - DO), (2) birth to first service (heifers) (or age at first service – AFS) or calving to first service (cows) (or waiting period - WP) and (3) days between first and last service (DFLS). The fertility of heifers and cows was determined by (1) number of services per conception (NSC), (2) conception rate at first service (CRFS) and (3) overall conception rate (CR). The prevalence of PP disorders (dystocia, retained placenta or RP, clinical endometritis, urovagina, cysts and anœstrus) was also determined. The monthly temperature and humidity index (THI) for the years 2013 - 2014 has been calculated. The body weight and average daily gain of heifer at 6, 12 and 16 months of age were 159, 280 and 351 kg and 690, 646 and 705 g/day respectively. The average daily milk yield per cow was 11.6 (± 0.5) kg. The average duration of lactation was 368 (± 100) days. The overall mean of AFS, DFLS and AC of heifers was 479 (± 80), 38 (± 80) and 517 (± 114) days, respectively. The NSC, CR and CRFS was 1.8 (± 1.4), 55% and 58%, respectively. A significant decrease in AFS and AC according to the year of birth and a significant increase in AFS with a heavier weight (> 320 kg) at first AI were observed. CRFS of heifers inseminated in 2013 was higher than that of heifers inseminated in 2014 (64% vs 50%, P <0.05). The monthly CR in heifers was negatively correlated with the monthly THI during observed period (P = 0.003). The overall mean of WP, DFLS, DO of cows was 109 (±52), 133 (±114) and 242 (±129), respectively. The mean for NSC, CR and CRFS was 4.3 (±2.7), 23 % and 14 %. A significant decrease in WP, DFLS, DO and NSC with an increase according to the year of calving was observed in this study. Calving occurring during rainy season was accompanied by a significant increase in WP. The presence of PP disorders was accompanied by an increase in WP (108 vs 98 days), DO (249 vs 216 days) and NSC (4.7 vs 3.9). A decrease in BCS between calving and day 60th (C60) and between day 60th and 120th PP resulted in a significant increase in WP and DO. The decrease in BCS between C60 also leaded to a significant reduction in CRFS (8 vs 18%, P <0.05). The year and season of insemination, and the BCS at insemination had a significant effect on the NSC and CR of cows. There was a negative correlation between monthly CR in cows and THI (r = -0645, P = 0.02). A total of 353 calvings and PP periods of 302 cows were observed. The prevalence of dystocia, RP, clinical endometritis, urovagin, PP anestrus and ovarian cysts was 24.4%, 16.4%, 19.2%, 5.6%, 49.9% and 6.3%, respectively. The primiparous cows had 1.7 times more risk of dystocia than the multiparous cows (29.9% vs 20.4%, P <0.05). Cows that calved in 2014 or in rainy season had 6 or 2.1 times more than risk of dystocia than cows that calved in 2013 (P <0.001) or in dry season (P <0.01), respectively. The frequency of RP was higher in 2014 than in 2013 (21.8% vs. 11.7%, P <0.01). Cows that calved in 2014 or in rainy season showed more frequently clinical endometritis than cows that calved in 2013 (OR = 3.03, P = 0.001) or in dry season (OR = 3.78, P <0.001). Dystocia (OR = 2.8; P = 0.003) and RP (OR = 4.7, P = 0.001) were the major risk factors of clinical endometritis. The difficult calving, clinical endometritis and insufficient BCS at calving (< 3) or day 30th in PP were accompanied by an increase in risk of type I anestrus. In conclusion, the reproductive performance was satisfactory for heifers, but poor for cows. The infertility and PP anestrus are the major factors responsible for this situation. Heat stress and under-nutrition are the major causes of infertility and PP anestrus. Moreover, the frequency of reproductive disorders (dystocia, RP, clinical endometritis and PP anestrus) is also important in this study. Dystocia and RP are the risk factors for clinical endometritis and this disorder also had a negative effect on fertility and resumption of ovarian activity in cows. [less ▲]

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