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See detailIntraspecific variation of copper tolerance of four endemic plant species from the katangan Copperbelt (D. R. Congo)
Boisson, Sylvain ULg; garin, olivier; Seleck, Maxime ULg et al

Conference (2014, August 04)

Harsh ecosystems are at the origin of speciation processes in plant communities. In metalliferous areas, plants develop physiological adaptations to tolerate metal excesses which lead to high species and ... [more ▼]

Harsh ecosystems are at the origin of speciation processes in plant communities. In metalliferous areas, plants develop physiological adaptations to tolerate metal excesses which lead to high species and population diversity. South of the Katanga province (D.R. Congo), plant communities occur on soils with one of the world’s largest concentrations of copper and cobalt. More than 600 species including 54 endemics are distributed along a copper gradient (up to 10 000 mg kg-1 available Cu) and the populations are isolated on more than 100 copper hills scattered in miombo forest. In order to improve restoration strategies of threatened species, we aimed to identify intraspecific copper tolerance of 4 endemic plant species from katangan copper outcrops: Crotalaria cobalticola, Diplolophium marthozianum, Gladiolus ledoctei and Triumfetta welwitschii. Seeds were collected in 3 different populations in the katangan Copperbelt and sown according three soil contamination modalities: control (no addition of Cu), 100 mg kg-1 and 1000 mg kg-1 of Cu concentration using hydrated copper (II) sulfate. For each combination (species x populations x soils), we had 10 repetitions. For each population, sample of 5 seeds was weighed before seedling in pot in November 2013. One individual by pot was kept for measures. Height (cm), number of leaves, number of flowers and number of fruits were measured once a week during one rainy season. For all species, no significant difference of copper tolerance appeared between populations. In contrast, populations had distinct germination rate and growth rate, especially for T. welwitshii and D. marthozianum. C. cobalticola grew significantly better in highly contaminated soil than other soils. G. ledoctei did not show any significant difference between populations and soil treatments. [less ▲]

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See detailEvaluation of [18F]UCB-H as a novel PET tracer for synaptic vesicle protein 2A in the brain.
Warnock, Geoffrey; Aerts, Joël ULg; Bahri, Mohamed Ali ULg et al

in Journal of Nuclear Medicine (The) (2014), 55(8), 1336-1341

Synaptic vesicle 2 (SV2) proteins are critical to proper nervous system function and are involved in vesicle trafficking. The SV2A isoform has been identified as the binding site of the antiepileptic ... [more ▼]

Synaptic vesicle 2 (SV2) proteins are critical to proper nervous system function and are involved in vesicle trafficking. The SV2A isoform has been identified as the binding site of the antiepileptic levetiracetam (LEV), making it an interesting therapeutic target for epilepsy. [18F]UCB-H is a novel PET imaging agent with a nanomolar affinity for human SV2A. Methods: preclinical PET studies were carried out in isoflurane anesthetized rats. Arterial input function was measured using an arteriovenous shunt and beta microprobe system. [18F]UCB-H was injected IV (140 ± 20 MBq bolus). Results: brain uptake of [18F]UCB-H was high, matching the expected homogeneous distribution of SV2A. The distribution volume (Vt) for [18F]UCB-H was calculated using Logan’s graphical analysis and the effect of LEV pretreatment on Vt measured. In control animals the mean whole-brain Vt was 9.76 ± 0.52 ml/cm3 (mean ± SD, n=4, test-retest), and the mean reproducibility in test-retest studies was 10.4 ± 6.5 %. Uptake of [18F]UCB-H was dose-dependently blocked by pretreatment with LEV (0.1 - 100 mg/kg IV). Conclusion: our results indicate that [18F]UCB-H is a suitable radiotracer for the imaging of SV2A in vivo. This is the first PET tracer for in vivo quantification of SV2A. The necessary steps for implementation of [18F]UCB-H production under GMP conditions and first in human studies are planned. [less ▲]

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See detailcompte rendu de : Geiger, Joseph. Hellenism in the East: studies on Greek intellectuals in Palestine.
Rochette, Bruno ULg

in Bryn Mawr Classical Review [=BMCR] (2014)

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See detailEn attendant Toussaint
Demoulin, Laurent ULg

E-print/Working paper (2014)

Présentation et analyse de deux courtes pièces, Rideau et Ni l'un ni l'autre, écrites par Jean-Philippe Toussaint en 1981, quand il était un jeune auteur inconnu influencé par Samuel Beckett.

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See detailX-rays from magnetic massive OB stars
Petit, V.; Cohen, D. H.; Nazé, Yaël ULg et al

in IAU Symposium (2014, August 01)

The magnetic activity of solar-type and low-mass stars is a well known source of coronal X-ray emission. At the other end of the main sequence, X-rays emission is instead associated with the powerful ... [more ▼]

The magnetic activity of solar-type and low-mass stars is a well known source of coronal X-ray emission. At the other end of the main sequence, X-rays emission is instead associated with the powerful, radiatively driven winds of massive stars. Indeed, the intrinsically unstable line-driving mechanism of OB star winds gives rise to shock-heated, soft emission (~0.5 keV) distributed throughout the wind. Recently, the latest generation of spectropolarimetric instrumentation has uncovered a population of massive OB-stars hosting strong, organized magnetic fields. The magnetic characteristics of these stars are similar to the apparently fossil magnetic fields of the chemically peculiar ApBp stars. Magnetic channeling of these OB stars' strong winds leads to the formation of large-scale shock-heated magnetospheres, which can modify UV resonance lines, create complex distributions of cooled Halpha emitting material, and radiate hard (~2-5 keV) X-rays. This presentation summarizes our coordinated observational and modelling efforts to characterize the manifestation of these magnetospheres in the X-ray domain, providing an important contrast between the emission originating in shocks associated with the large-scale fossil fields of massive stars, and the X-rays associated with the activity of complex, dynamo-generated fields in lower-mass stars. [less ▲]

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See detailA Deep Chandra Observation of the Giant H II Region N11. I. X-Ray Sources in the Field
Nazé, Yaël ULg; Wang, Q. Daniel; Chu, You-Hua et al

in Astrophysical Journal Supplement Series (2014), 213

A very sensitive X-ray investigation of the giant H II region N11 in the Large Megallanic Cloud was performed using the Chandra X-ray Observatory. The 300 ks observation reveals X-ray sources with ... [more ▼]

A very sensitive X-ray investigation of the giant H II region N11 in the Large Megallanic Cloud was performed using the Chandra X-ray Observatory. The 300 ks observation reveals X-ray sources with luminosities down to 10[SUP]32[/SUP] erg s[SUP]–1[/SUP], increasing the number of known point sources in the field by more than a factor of five. Among these detections are 13 massive stars (3 compact groups of massive stars, 9 O stars, and one early B star) with log (L [SUB]X[/SUB]/L [SUB]BOL[/SUB]) ~–6.5 to –7, which may suggest that they are highly magnetic or colliding-wind systems. On the other hand, the stacked signal for regions corresponding to undetected O stars yields log (L [SUB]X[/SUB]/L [SUB]BOL[/SUB]) ~–7.3, i.e., an emission level comparable to similar Galactic stars despite the lower metallicity. Other point sources coincide with 11 foreground stars, 6 late-B/A stars in N11, and many background objects. This observation also uncovers the extent and detailed spatial properties of the soft, diffuse emission regions, but the presence of some hotter plasma in their spectra suggests contamination by the unresolved stellar population. [less ▲]

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See detailStandardization of DiaSorin and Roche automated third generation PTH assays with an international standard: impact on clinical populations
CAVALIER, Etienne ULg; DELANAYE, Pierre ULg; LUKAS, Pierre ULg et al

in Clinical Chemistry & Laboratory Medicine (2014), 52(8), 1137-41

Background: Standardization of parathyroid hormone (PTH) assays is a major issue, especially in hemodialyzed (HD) patients. Two automated third generation PTH assays (Roche Elecsys and DiaSorin Liaison ... [more ▼]

Background: Standardization of parathyroid hormone (PTH) assays is a major issue, especially in hemodialyzed (HD) patients. Two automated third generation PTH assays (Roche Elecsys and DiaSorin Liaison) are now available. These assays are specific for the (1-84) PTH and do not cross-react with the (7-84) fragment, contrary to second generation (intact) assays. We aimed to calibrate the two methods against the WHO International PTH Standard (IS) 95/646 to see if the two assays could provide comparable results in a population of healthy subjects, HD patients and patients suffering from primary hyperparathyroidism (PHP). Methods: We selected 79 healthy subjects and two populations of patients presenting PTH disorders: 56 HD and 27 PHP patients. We reconstituted the IS in a pool of human serum containing undetectable levels of 1-84 PTH and prepared 13 serum standards ranging from 0 to 2000 pg/mL. The standards were run on the two instruments to calibrate the assays on the IS. The different populations were run before and after restandardization. Results: As these kits were differently calibrated, the results obtained after restandarization were significantly different. Restandardization process improved concordance between assays and, taking the analytical variability of the two kits into account, the results could be considered to be similar. Conclusions: Restandardization of automated third generation PTH assays with the WHO 1-84 PTH Standard significantly reduces inter-method variability. Reference ranges and raw values are totally transposable from one method to the other in healthy subjects, but also in diseased patients, e.g., with HD or those suffering from PHP. [less ▲]

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See detailWASP-117b: a 10-day-period Saturn in an eccentric and misaligned orbit
Lendl, Monika ULg; Triaud, A. H. M. J.; Anderson, D. R. et al

in Astronomy and Astrophysics (2014), 568

We report the discovery of WASP-117b, the first planet with a period beyond 10 days found by the WASP survey. The planet has a mass of M_p = 0.2755 (+/-0.0090) M_jup, a radius of R_p = 1.021 (-0.065 +0 ... [more ▼]

We report the discovery of WASP-117b, the first planet with a period beyond 10 days found by the WASP survey. The planet has a mass of M_p = 0.2755 (+/-0.0090) M_jup, a radius of R_p = 1.021 (-0.065 +0.076) R_jup and is in an eccentric (e = 0.302 +/-0.023), 10.02165 +/- 0.00055 d orbit around a main-sequence F9 star. The host star's brightness (V=10.15 mag) makes WASP-117 a good target for follow-up observations, and with a planetary equilibrium temperature of T_eq = 1024 (-26 +30) K and a low planetary density (rho_p = 0.259 (-0.048 +0.054) rho_jup) it is one of the best targets for transmission spectroscopy among planets with periods around 10 days. From a measurement of the Rossiter-McLaughlin effect, we infer a projected angle between the planetary orbit and stellar spin axes of beta = -44 (+/-11) deg, and we further derive an orbital obliquity of psi = 69.5 (+3.6 -3.1) deg. Owing to the large orbital separation, tidal forces causing orbital circularization and realignment of the planetary orbit with the stellar plane are weak, having had little impact on the planetary orbit over the system lifetime. WASP-117b joins a small sample of transiting giant planets with well characterized orbits at periods above ~8 days. [less ▲]

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See detailModel-Based Computation of Total Stressed Blood Volume from a Preload Reduction Experiment
Pironet, Antoine ULg; Desaive, Thomas ULg; Chase, J. Geoffrey et al

Conference (2014, August)

Total stressed blood volume is an important parameter for both doctors and engineers. From a medical point of view, it has been associated with the success or failure of fluid resuscitation therapy, which ... [more ▼]

Total stressed blood volume is an important parameter for both doctors and engineers. From a medical point of view, it has been associated with the success or failure of fluid resuscitation therapy, which is a treatment for cardiac failure. From an engineering point of view, this parameter dictates the cardiovascular system's dynamic behavior. Current methods to determine this parameter involve repeated phases of circulatory arrests followed by fluid administration. In this work, a method is developed to compute stressed blood volume from preload reduction experiments. A simple six-chamber cardiovascular system model is used and its parameters are adjusted to pig experimental data. The parameter adjustment process has three steps: (1) compute nominal values for all model parameters; (2) determine the most sensitive parameters; and (3) adjust only these sensitive parameters. Stressed blood volume was determined sensitive for all datasets, which emphasizes the importance of this parameter. The model was able to track experimental trends with a maximal mean squared error of 11.77 %. Stressed blood volume has been computed to range between 450 and 963 ml, or 15 to 28 ml/kg, which matches previous independent experiments on pigs, dogs and humans. Consequently, the method proposed in this work provides a simple way to compute total stressed blood volume from usual hemodynamic data. [less ▲]

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See detailModel-Based Computation of Total Stressed Blood Volume from a Preload Reduction Experiment
Pironet, Antoine ULg; Desaive, Thomas ULg; Chase, J. Geofrrey et al

in Preprints of the 19th World Congress (2014, August)

Total stressed blood volume is an important parameter for both doctors and engineers. From a medical point of view, it has been associated with the success or failure of fluid resuscitation therapy, which ... [more ▼]

Total stressed blood volume is an important parameter for both doctors and engineers. From a medical point of view, it has been associated with the success or failure of fluid resuscitation therapy, which is a treatment for cardiac failure. From an engineering point of view, this parameter dictates the cardiovascular system’s dynamic behavior. Current methods to determine this parameter involve repeated phases of circulatory arrests followed by fluid administration. In this work, a method is developed to compute stressed blood volume from preload reduction experiments. A simple six-chamber cardiovascular system model is used and its parameters are adjusted to pig experimental data. The parameter adjustment process has three steps: (1) compute nominal values for all model parameters; (2) determine the most sensitive parameters; and (3) adjust only these sensitive parameters. Stressed blood volume was determined sensitive for all datasets, which emphasizes the importance of this parameter. The model was able to track experimental trends with a maximal mean squared error of 11.77 %. Stressed blood volume has been computed to range between 450 and 963 ml, or 15 to 28 ml/kg, which matches previous independent experiments on pigs, dogs and humans. Consequently, the method proposed in this work provides a simple way to compute total stressed blood volume from usual hemodynamic data. [less ▲]

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See detailRegional, Interregional and Global Arrangements and Multilateral Organizations
Santander, Sébastian ULg

in Telò, Mario (Ed.) European Union and New Regionalism. Regional actors and global governance in a post-hegemonic era (2014)

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See detailThe instability strip of ZZ Ceti white dwarfs
Van Grootel, Valérie ULg; Fontaine, G.; Brassard, P. et al

Conference (2014, August)

The determination of the location of the theoretical ZZ Ceti instability strip in the log g − Teff diagram has remained a challenge over the years, due to the lack of a suitable treatment for convection ... [more ▼]

The determination of the location of the theoretical ZZ Ceti instability strip in the log g − Teff diagram has remained a challenge over the years, due to the lack of a suitable treatment for convection in these stars. We report here a detailed stability survey over the whole ZZ Ceti regime, including the low and extremely low masses. We computed to this aim 29 evolutionary sequences of DA models with various masses, chemical layering, and core compositions. These models are characterized by the so- called ML2/α=1.0 convective efficiency and take into account the important feedback effect of convection on the atmospheric structure. We computed pulsation spectra for these models with the Liège nonadiabatic pulsation code MAD, which is the only one to conveniently incorporate a full time-dependent convection treatment and, thus, provides the best available description of the blue edge of the instability strip. On the other hand, given the failure of all nonadiabatic codes to account properly for the red edge of the strip, including MAD, we tested the idea that the red edge is due to energy leakage through the atmosphere. Using this approach, we found that our theoretical ZZ Ceti instability strip accounts remarkably well for the boundaries of the empirical strip. [less ▲]

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See detailImprovement of defect detection in shearography by using Principal Component Analysis
Vandenrijt, Jean-François ULg; Lièvre, Nicolas; Georges, Marc ULg

in Proceedings of Conference on Interferometry XVII: Techniques and Analysis (2014, August)

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See detailA First Look at the Nonadiabatic Properties of Pulsating Accreting White Dwarfs of the GW Lib Type
Van Grootel, Valérie ULg; Fontaine, G.; Brassard, P. et al

Poster (2014, August)

We present results of a detailed stability survey of the pulsation properties of accreting white dwarfs of the GW Lib type. This is based on several state-of-the- art white dwarf evolutionary sequences ... [more ▼]

We present results of a detailed stability survey of the pulsation properties of accreting white dwarfs of the GW Lib type. This is based on several state-of-the- art white dwarf evolutionary sequences with varying envelope compositions, from pure hydrogen to pure helium. Using the same tools as in Van Grootel et al. (2013), where we have presented the first consistent view of the ZZ Ceti instability strip, we have mapped the GW Lib instability strip over the effective temperature-surface gravity plane, and as a function of envelope composition. We find that the location of the GW Lib instability domain is a strong and continuous function of the assumed envelope composition. We can accomodate all of the known GW Lib pulsators in various strips according to their atmospheric compositions. [less ▲]

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See detailWhich agritourism for which suburban countryside? A heuristic and comparative analysis in Wallonia and Grand-Duchy of Luxembourg (part 2)
Dubois, Charline ULg; Schmitz, Serge ULg

in Ianos, Ioan (Ed.) Rural life and rural systems between tradition and integrated urban-rural development (2014, August)

Mutations, transformations, transitions are keywords which open the door to many questions regarding the global European agriculture. The resources of the rural countryside in Europe are subject to many ... [more ▼]

Mutations, transformations, transitions are keywords which open the door to many questions regarding the global European agriculture. The resources of the rural countryside in Europe are subject to many pressures. Agricultural activities are decreasing and farmers are losing importance. In some northwestern European countryside, the declining agriculture compels to diversify activities in farms. Some farmers need to rethink their business goals in order to successfully sustain their operations in the economic space. In many areas, one of the solutions suggested is the development of agritourism. Agritourism in Wallonia and in the Grand-Duchy of Luxembourg is a tourist activity proposed by the farmer in his farm. While addressing the challenges and countering threats of their agriculture, both suburban areas present many advantages and opportunities for tourism development. Different tourist and leisure developments are conceived and proposed. The activity is reinforced by popular images of sustainability and ecology. Is agritourism a universal solution or is it a reflected contextualized solution? In the Tel-Aviv CSRS meeting, in 2010, we presented a communication on this issue. While the theoretical review and the aim of the first paper were well presented, the empirical results were not well documented because we were at the beginning of the PhD research. Today, we propose, in this paper, to improve information and to answer to the different comments from the members of the commission. Agritourism should be defined, localized, differentiated. Between 2010 and 2014, we conducted interviews of Walloon and Luxembourg tenants (n = 33), surveys among potential tourists (n = 1148) in seven tourist places, interviews of privileged witnesses (n = 31), and field observations. Working on two regions of Western Europe which had not been analyzed previously, the Walloon and Luxembourg suburban countryside, we want to understand the agritourism dynamics, the factors that influence the location and development, and the images of farm tourism. The purpose of this research is to understand the geographical relationship between agritourism, countryside, local resources, agriculture, and tourism specialization. This issue is underdeveloped in the literature and our PhD thesis contributes to fill this gap. We scrutinize the spatial distribution of agritourism in both regions, the logic of emergence of tourism in a farm, the links between these tourist functions and these agricultural functions. We analysed the tenants and visitors’ reasons and motivations in regards of the regional and local context. Finally, we build a typology of the countryside according to agritourism. We conclude that the farm diversification should pay attention to several local and regional factors to succeed in a win-win combination of tourism and agriculture. These factors are listed in a heuristic model, which is a user-friendly tool to think future development of agritourism in the European countryside. [less ▲]

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See detailDeveloping situational judgment tests to assess organizational citizenship behaviours
Lothe, Benoit ULg; Hansez, Isabelle ULg

Conference (2014, August)

a) Purpose As Organizational Citizenship Behaviours (OCBs) positively influence a number of important outcomes (e.g. job performance, unit productivity, organizational efficiency, etc.) and are valued by ... [more ▼]

a) Purpose As Organizational Citizenship Behaviours (OCBs) positively influence a number of important outcomes (e.g. job performance, unit productivity, organizational efficiency, etc.) and are valued by managers as well, Organ, Podsakoff and Podsakoff (2010) assert the need “to try to identify and select those job candidates who have a propensity to exhibit these behaviours” (p.314). This study provides some empirical evidence about using Situational Judgment Tests (SJTs) for this specific target and allows us to discuss the main methodological issues in the development of such SJTs. b) Method Based on relevant best practices and recommendations from the literature (e.g. Weekley, Ployhart & Holtz, 2006), two distinct SJTs were especially developed to comply with OCBs assessment. The two SJTs differ on their job specificity degree (project manager in the industrial sector vs transversal function in the services sector), both propose ten different work related situations and, for each stem, five action proposals are available. Data were collected through online survey on two different samples (220 white collars professionals and 291 university students). Professionals were allowed to choose which SJT they wanted to participate, students were randomized within the two SJTS. An experimental manipulation of the response instructions (ipsative vs normative) was added within the student sample. OCBs were concurrently collected using self-reported measurement scales. c) Results In both samples (respectively professionals and students), the internal consistency was higher for the “job specific” SJT (α = .79 & .81) than for the “transversal job” SJT (α = .49 & 64). Notwithstanding, significant relations were found between the SJT scores and overall OCB ratings for both of the SJT forms in each of the two samples (r ranged from .30 to .57). Other specifics findings also provided substantial evidence for the concurrent validity of the SJTs to measure sub-dimensions of OCBs (altruism, courtesy, civic virtue, sportsmanship, loyalty and voice). d) Conclusions This study is, to our knowledge, the first to address the development and validation of a SJT for the assessment of OCBs. Review of the literature indicates that researches on techniques to predict OCBs are scarce and the present findings appear to surpass the average personality traits validity coefficients (r= .20) according to Organ & al. (2010)’s meta-analysis. There are two main practical implications. The first is the opportunity to use OCBs-SJTs as an alternative to assess applicants OCBs for job-specific or generic personnel selection issue. The second is to provide methodological development advices (e.g. the choice of response instruction) to ensure the SJT match the OCBs assessment requirement. Principal current limitations call for further research development that will be discussed: using different sources of OCBs rating, testing the incremental validity on personality tests, determining whether OCBs-SJTs are correlated with cognitive ability and establishing criterion validity with job performance. [less ▲]

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See detailNatural intrauterine infection with Schmallenberg virus in malformed newborn calves: pathology and distribution of viral RNA
Bayrou, Calixte ULg; Garigliany, Mutien-Marie ULg; Sarlet, Michaël ULg et al

in Emerging Infectious Diseases (2014), 20(8),

We comprehensively surveyed morphologic alterations in calves naturally infected in utero by Schmallenberg virus (SBV) and born deformed. SBV-specific RNA was distributed unevenly in different tissues ... [more ▼]

We comprehensively surveyed morphologic alterations in calves naturally infected in utero by Schmallenberg virus (SBV) and born deformed. SBV-specific RNA was distributed unevenly in different tissues. Implications for diagnosic procedures are highlighted. [less ▲]

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