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See detailTowards a covering aerospray method for quantitative analyses of pharmaceutical tablets using surface-enhanced Raman chemical imaging (SER-CI)
Cailletaud, Johan ULiege; De Bleye, Charlotte ULiege; Dumont, Elodie ULiege et al

Conference (2017, September 22)

In recent years, the use of SERS-CI in pharmaceutical sciences has increased in order to study the distribution of low-dose compounds in solid dosage forms [1]. This technique allows to improve the ... [more ▼]

In recent years, the use of SERS-CI in pharmaceutical sciences has increased in order to study the distribution of low-dose compounds in solid dosage forms [1]. This technique allows to improve the sensitivity of conventional Raman microscopy and to reduce significantly the image acquisition time by exalting the signal information. However, the applications of SERS-CI in the pharmaceutical field remain limited, especially due to the difficulty of obtaining a homogeneous deposit of metallic nanoparticles on the sample surface. Generally, the covering method used on the tablet is a drop casting deposition due to its simplicity and rapidity of implementation. Despite the colloidal solution deposit is not fully controlled. The inhomogeneous covering is the result of the “coffee-ring” effect that concentrates the nanoparticles at the edges of the droplet [2]. This implies remarkable variations of the SERS analyte signal’s intensity at different places. For a more reproducible and homogeneous coating, an aerospray method using a homemade apparatus was developed (Figure 1). The device is composed with a pair of coaxial tubes, the colloidal solution is pulled through the inner tube from a syringe pump and the outer tube is connected to a source of high pressure gas. Nitrogen, used as a nebulizing gas, creates a flow of small droplets of nanoparticles that are nearly dry when they hit the sample surface. The aerospray device is easy to implement and the entire surface of the tablet is covered by the SERS substrate in a homogeneous way. By using this covering method, the potential of SERS-CI is improved and making it a suitable technique for quantitative analyses of low drug concentrations or impurities in pharmaceutical tablets. [less ▲]

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See detailLes interactions enseignant/enfants comme soutien au développement langagier des enfants en classe maternelle
Leroy, Sandrine ULiege; Bergeron-Morin, Lisandre ULiege; Desmottes, Lise ULiege et al

in Les entretiens de Bichat : les entretiens d'orthophonie 2017 : Les pathologies du langage chez l'enfant de moins de 6 ans: facteurs de risque (FR), facteurs de protection (FP) (2017, September 22)

L'école maternelle constitue un contexte privilégié pour soutenir le développement du langage et de la communication des enfants. La qualité des interactions entre l’enseignant et les enfants de sa classe ... [more ▼]

L'école maternelle constitue un contexte privilégié pour soutenir le développement du langage et de la communication des enfants. La qualité des interactions entre l’enseignant et les enfants de sa classe est reconnue comme étant l’aspect le plus déterminant de la qualité éducative, notamment en ce qui concerne le développement langagier. Cet article a pour objectif de faire un survol de la littérature sur le développement du langage des enfants en contexte préscolaire, sur le rôle que peut y jouer l’enseignant, ce qui ouvre des perspectives quant aux modalités de développement professionnel des enseignants en maternelle. [less ▲]

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Peer Reviewed
See detailUn MOOC sur l’enseignement du FLE : la question de la médiation des savoirs et de l’évaluation des savoir-faire
Meunier, Deborah ULiege; Thonard, Audrey ULiege

Conference (2017, September 22)

« Ma classe de FLE » est un projet de MOOC destiné à de (futurs) enseignants de français langue étrangère. Constitué de 8 modules interactifs, ce MOOC vise à développer les connaissances et compétences ... [more ▼]

« Ma classe de FLE » est un projet de MOOC destiné à de (futurs) enseignants de français langue étrangère. Constitué de 8 modules interactifs, ce MOOC vise à développer les connaissances et compétences des participants en matière de gestion des interactions (orales et écrites) et des ressources (notamment numériques), mais aussi de développement des compétences grammaticales et interculturelles des apprenants. A partir d’exemples concrets d’activités, nous interrogerons d’un point de vue didactique deux aspects liés à ce dispositif d’enseignement/apprentissage innovant : la médiation des savoirs et les pratiques d’évaluation. En effet, les enjeux d’une pédagogie renversée, où l’apprenant est au centre de l’apprentissage et le numérique à son service, impliquent une (re)configuration des rôles des acteurs du dispositif (apprenants, enseignants, tuteurs, animateurs) dans la médiation des savoirs d’une part, et l’évaluation des acquis d’apprentissage d’autre part. Nous verrons comment nous avons mis en œuvre la co-construction collaborative et ouverte de savoirs, et quels dispositifs d’évaluation (par les pairs, par essai-erreur) nous avons proposés, en accord avec la pédagogie (inter)active dans laquelle s’inscrit notre projet de MOOC. [less ▲]

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See detailAngels and Constellations in Australian Fiction: Profane Illumination and Topological Temporality in Gail Jones's A Guide to Berlin
Belleflamme, Valérie-Anne ULiege

Scientific conference (2017, September 22)

This seminar will focus on Australian writer Gail Jones’s sixth novel, A Guide to Berlin, published in 2015. Named after a short story by Vladimir Nabokov, Jones’s guide portrays the advent of a small ... [more ▼]

This seminar will focus on Australian writer Gail Jones’s sixth novel, A Guide to Berlin, published in 2015. Named after a short story by Vladimir Nabokov, Jones’s guide portrays the advent of a small international community through the convergence in snowy Berlin of six foreign travellers joined together in their devotion to Nabokov’s literary œuvre. Drawing on the psychogeography of Berlin, with its “shifting angles” and “receding perspectives,” its “corridors between spaces” and “immaterial traces,” this seminar aims at bringing together Michel Serres’s topological reading of time, Walter Benjamin’s convoluted view of history, and Paul Celan’s speaking shadows and at textualising their precepts in Jones’s fiction. [less ▲]

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Peer Reviewed
See detailPsychological Predictors and Consequences of Hearing Health Behaviors in Older Adults
Marquet, Manon ULiege; Chasteen, Alison L; Plaks, Jason E et al

Poster (2017, September 22)

Introduction: Hearing loss is a common chronic condition affecting older adults in Western populations [1, 2]. Even if older adults could benefit from hearing aid use, they are reluctant to wear them [1 ... [more ▼]

Introduction: Hearing loss is a common chronic condition affecting older adults in Western populations [1, 2]. Even if older adults could benefit from hearing aid use, they are reluctant to wear them [1]. The purpose of the present study was twofold: a) to examine whether older adults’ implicit theories regarding the modifiability of abilities in general would predict their hearing health behaviors; and (b) to assess consequences of these behaviors on subjective aging. Methods: One hundred and sixty-three older adults (Mean age = 68.62, SD = 5.40) completed, among other questionnaires, questions assessing their implicit theories of ability (i.e., seeing general abilities as fixed vs. improvable with effort [3]) and their subjective age (i.e., felt age, do age, look age, and interest age [4]). They also reported their perceptions of the benefits of various hearing health behaviors for slowing the effects of aging (i.e., getting their hearing tested and using hearing aids) as well as their intentions to engage in those behaviors. Results: We found that the more older people considered that abilities are alterable, the more they perceived hearing health behaviors as being beneficial, which in turn increased their intentions to engage in these behaviors. Also, the greater their intentions, the younger subjective age they reported. Key conclusions: These relationships between implicit theories, hearing health behaviors, and subjective age are particularly important to take into account. Indeed, neglecting hearing problems and experiencing an older subjective age may have detrimental health-related outcomes over time [5, 6]. 1. Feder, K., Michaud, D., Ramage-Morin, P., McNamee, J., & Beauregard, Y. (2015). Prevalence of hearing loss among Canadians aged 20 to 79: Audiometric results from the 2012/2013 Canadian Health Measures Survey. Health Reports, 26(7), 18-25. 2. Lin, F. R., Thorpe, R., Gordon-Salant, S., & Ferrucci, L. (2011). Hearing loss prevalence and risk factors among older adults in the United States. The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences, 66(5), 582-590. doi: doi:10.1093/gerona/glr002 3. Dweck, C. S. (1999). Self-theories: Their role in motivation, personality, and development. Philadephia, PA: Psychology Press. 4. Kastenbaum, R., Derbin, V., Sabatini, P., & Artt, S. (1972). “The ages of me”: Toward personal and interpersonal definitions of functional aging. The International Journal of Aging and Human Development, 3(2), 197-211. 5. Bainbridge, K. E., & Wallhagen, M. I. (2014). Hearing loss in an aging American population: Extent, impact, and management. Annual Review of Public Health, 35, 139-152. doi: 10.1146/annurev-publhealth-032013-182510 6. Kotter-Grühn, D., Kornadt, A. E., & Stephan, Y. (2015). Looking beyond chronological age: Current knowledge and future directions in the study of subjective age. Gerontology, 62(1), 86-93. doi: 10.1159/000438671 [less ▲]

Detailed reference viewed: 29 (1 ULiège)
Peer Reviewed
See detailSemantic externalism(s) and cognitive transparency
Leclercq, Bruno ULiege; De Brabanter, Philippe

Conference (2017, September 22)

Detailed reference viewed: 31 (1 ULiège)
See detail‘Once Upon A Time’ ou le contrôle de la narration
Claisse, Frédéric ULiege; Huppe, Justine ULiege

E-print/Working paper (2017)

Ce billet de blog analyse les liens entre "ELIPSIA", une série de court-métrages réalisée par Frédéric DARRAS entre 2012 et 2016, et le projet de recherche STORYFIC, consacré aux effets du storytelling ... [more ▼]

Ce billet de blog analyse les liens entre "ELIPSIA", une série de court-métrages réalisée par Frédéric DARRAS entre 2012 et 2016, et le projet de recherche STORYFIC, consacré aux effets du storytelling sur l'écriture de fiction contemporaine, et plus particulièrement aux pouvoirs de la fiction. Après avoir décrit les enjeux posés par la série, l'article développe une série de parallèles avec les préoccupations d'auteurs français contemporains (C. Delaume, C. de Toledo, P. Vasset, A. Damasio), qui nourrissent le même rapport ambivalent à la fiction: à la fois dénoncée pour son emprise sur nos existences et son caractère aliénant, mais aussi valorisée pour ses promesses de réappropriation et d'émancipation. [less ▲]

Detailed reference viewed: 32 (1 ULiège)
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See detailMyoferlin controls mitochondrial structure in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness
Rademaker, Gilles ULiege; Hennequière, Vincent ULiege; Brohée, Laura ULiege et al

Poster (2017, September 22)

Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer, and the third leading cause of cancer related death. Therapeutic options remain very limited and are still based on ... [more ▼]

Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer, and the third leading cause of cancer related death. Therapeutic options remain very limited and are still based on classical chemotherapies. Cell fraction can survive to the chemotherapy and is responsible for tumor relapse. It appears that these cells rely on OXPHOS for survival. Myoferlin, a membrane protein involved in cell fusion was recently shown by our laboratory to be overexpressed in pancreatic cancer. In the present study, we discovered that myoferlin was more expressed in cell lines undergoing oxidative phosphorylation (OXPHOS) than in glycolytic cell lines. In the former cell lines, we showed that myoferlin silencing reduced OXPHOS activity and forced cells to switch to glycolysis. The decrease in OXPHOS activity is associated with mitochondrial network disorganization. Dynamin-related protein (DRP)-1 phosphorylation led us to suggest mitochondrial fission, reducing cell proliferation, ATP production and inducing autophagy and ROS accumulation. To confirm the clinical importance of myoferlin in PDAC, we showed that low myoferlin expression was significantly correlated to high overall survival. Myoferlin staining of PDAC sections was negatively correlated with several 18FDG PET indices indicating that glycolytic lesions had less myoferlin. As the mitochondrial function is demonstrated to enhance the cell resistance to the treatment, the metabolic switch forced by myoferlin silencing could open up a new perspective in the development of therapeutic strategies. [less ▲]

Detailed reference viewed: 59 (19 ULiège)
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See detailTowards the development of a dual mode fluorescence/SERS dopamine aptasensor
Dumont, Elodie ULiege; De Bleye, Charlotte ULiege; Cailletaud, Johan ULiege et al

Poster (2017, September 21)

This work was dedicated to the development of a dual mode fluorescence and surface-enhanced Raman scattering (SERS) dopamine aptasensor. The preparation of the aptasensor was first optimised. Thereafter ... [more ▼]

This work was dedicated to the development of a dual mode fluorescence and surface-enhanced Raman scattering (SERS) dopamine aptasensor. The preparation of the aptasensor was first optimised. Thereafter, calibration curves were realised by means of fluorescence quenching and SERS. Finally, the specificity of both methods was tested. [less ▲]

Detailed reference viewed: 41 (10 ULiège)
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See detailQuelques pistes pour relancer la foresterie sociale et la participation en Afrique centrale
Vermeulen, Cédric ULiege

Conference (2017, September 21)

Detailed reference viewed: 69 (22 ULiège)
See detailHealing effect of controlled anti-electromigration on conventional and high-Tc superconducting nanowires
Baumans, Xavier ULiege; Lombardo, Joseph ULiege; Brisbois, Jérémy ULiege et al

Conference (2017, September 21)

At the present time, electron beam lithography (EBL) is considered as the reference technique for nanoscale patterning. However, making nanostructures below the sub-10 nm scale is still challenging due to ... [more ▼]

At the present time, electron beam lithography (EBL) is considered as the reference technique for nanoscale patterning. However, making nanostructures below the sub-10 nm scale is still challenging due to broadening effects (forward electron scattering, backscattering, electrostatic charging…), and requires strong investment in terms of cost for state-of-the-art EBL systems. In this sense, alternative methods are continuously explored in order to make such nanofabrication easily reachable. A promising approach consists of inducing atomic diffusion by a large current density. This phenomenon, called electromigration (EM), and well known since the 60’s as a failure mechanism in metallic interconnections [1], still attracts interests from scientists and engineers for its great potential for fabrication of microstructures and for its reversibility character [2, 3]. In this work, we show that the combination of electromigration and anti-electromigration allows the precise tuning of superconducting properties of Al nanoconstrictions and we also observe the reversibility of electromigration failure for this material (see Fig. 1). The same process has been applied on Nb, leading to a more irreversible process, and La2 xCexCuO4. For the latter material, we show that selective migration of oxygen atoms and the consequent doping modification induces a transition from a superconducting state to an insulating state in a reversible way [4]. We also discussed the possibility to enhance the electromigration technique by replacing the complex feedback control by a technique of electropulsing. These researches have direct practical impact as a method to explore the dependence of the characteristic parameters on the exact oxygen content and pave the way for a reversible control of local properties of nanowires. [less ▲]

Detailed reference viewed: 26 (5 ULiège)
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See detailAgeism and dementia stigma among healthcare professionals
Schroyen, Sarah ULiege; Adam, Stéphane ULiege; Missotten, Pierre ULiege

Poster (2017, September 21)

Detailed reference viewed: 37 (3 ULiège)
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Peer Reviewed
See detailFacultative paedomorphosis in pond-breeding newts
Denoël, Mathieu ULiege

Conference (2017, September 21)

Detailed reference viewed: 27 (8 ULiège)
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See detailEffect of solution treatment on the fracture mechanisms of AlSi10Mg parts produced by Selective Laser Melting
Delahaye, Jocelyn ULiege; Mertens, Anne ULiege; Dedry, Olivier ULiege et al

Poster (2017, September 21)

Al alloy AlSi10Mg processed by Selective Laser Melting (SLM) displays high hardness and tensile strength due to its very fine eutectic microstructure [1]. However, as-built material exhibits low ductility ... [more ▼]

Al alloy AlSi10Mg processed by Selective Laser Melting (SLM) displays high hardness and tensile strength due to its very fine eutectic microstructure [1]. However, as-built material exhibits low ductility which is detrimental for applications where a high resilience is needed. To overcome this issue, solution heat treatment can be applied to soften and ductilize the material [2]. The very fine eutectic microstructure then turns into a dispersion of coarse globular Si precipitates. The distribution of Si precipitates seems to play a role in the fracture mechanism in as-built as well as solutionized tempers, but this effect is not yet fully understood [1,3]. Moreover, the lack of quantitative data makes it difficult to link precisely the fracture mechanisms to specific microstructural features. This study aims at investigating the role of the Si phase in the rupture mechanism, for both as-built and solutionized samples. It will focus more particularly on the heterogeneity of the distribution of Si precipitates where cracks are more likely to occur. Al cells size, along with the volume fraction and distribution of Si precipitates have been quantified by SEM image analysis. Al lattice parameter and Si crystallite size have been determined by X-ray diffraction/Rietveld analysis. For the image analysis, two types of specific zones have been observed i.e. the core and boundary of melt pools and Al grains, at different locations for representativity. These quantitative data have been compared with typical features observed on the fractured surface of tensile specimen. 1. D.-K. Kim et al. J. Alloys Compd. 686 (2016) 281. 2. W. Li et al., Mat. Sci. & Eng. A. 663 (2016) 116, 3. N.T. Aboulkhair et al. Mat. Sci. & Eng. A. 667 (2016) 139. [less ▲]

Detailed reference viewed: 50 (5 ULiège)
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See detailMedia content for value and growth stocks
Lambert, Marie ULiege; Moreno Miranda, Nicolas ULiege

Scientific conference (2017, September 21)

This paper aims at providing new insights on the risk drivers underly- ing the value premium documented by Fama and French (1993). By using news stories supplied by Thomson Reuters, we seek to explain ... [more ▼]

This paper aims at providing new insights on the risk drivers underly- ing the value premium documented by Fama and French (1993). By using news stories supplied by Thomson Reuters, we seek to explain comove- ment in value and growth stock returns from common information factors embedded in news. We also distinguish between information coming from common news stories and idiosyncratic shocks concerning a smaller subset of firms. This framework allows us to answer three questions: 1) Is there a common risk factor in the news which explains the value anomaly? 2) Is idiosyncratic news information priced? and 3) Does the amount of media attention to an information prime over the polarity of this information? [less ▲]

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Peer Reviewed
See detailPerformance-based fire design and the U.S. prescriptive guidelines: A comparative study
Elhami Khorasani, Negar; Fang, Chenyang; Gernay, Thomas ULiege

in Proceedings of the 39th IABSE Symposium (2017, September 21)

Current codes and standards for fire design of structures in the United States are mainly based on design at the component level using prescriptive approaches, while performance-based design for fire can ... [more ▼]

Current codes and standards for fire design of structures in the United States are mainly based on design at the component level using prescriptive approaches, while performance-based design for fire can be used to address the needs for designing modern buildings with cost-effective solutions. Previous research shows that, when system-level performance is considered, fire protection on secondary beam elements in composite steel-concrete floor systems is not necessary due to the development of a membrane action in the concrete slab during fire. This study compares the fire design of a 9-story office building using prescriptive and performance-based designs. The safety levels of the two designs are investigated and compared. It is shown that performance-based design can be used to achieve the required level of safety currently enforced in the U.S. prescriptive guidelines, while providing an opportunity for cost reduction in fire protection material. [less ▲]

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See detailDéfinition d’un outil d’aide à la décision spatiotemporel structurant et articulant les potentialités de développement agricole : cas du Niger
Andres, Ludovic ULiege

Doctoral thesis (2017)

The concern about food insecurity in rural populations needs to be rethought and adapted to the overall living conditions of households by shifting to a concentrated spatial scale and a long-term analysis ... [more ▼]

The concern about food insecurity in rural populations needs to be rethought and adapted to the overall living conditions of households by shifting to a concentrated spatial scale and a long-term analysis. This change will allow identifying territories on a finer scale than the national level in order to allocate development objectives and to link them to areas with high development potential. The finer level of analysis will also allow regrouping the actions carried out on a smaller scale in order to structure all the activities carried out on the targeted area and population. The general comment that the development and emergency aid has been focused in circumscribed areas and that the level of analysis is based on two scales, one "macro" (national, regional, departmental) and the other "micro" (village, community, household, individual and community) reinforces the need to create an intermediate level of analysis. The latter will serve to improve the structure other actions carried out at different levels and the articulation of the activities to be carried out and the targeted population. From a state of the art analysis of subject such as development, targeting, territory, food security, resilience, etc; different finding have led to the definition of a major question and an objective which form the core structure of the present dissertation. The research question is defined as "how to structure the targeting and identification of areas with high potential to articulate all the emergency and development actions carried out on several scales of analysis?”. At the end of these observations, the objective of this research is "the establishment of a tool to support spatial and temporal decision making in structuring the emergency and development actions and targeting of populations subjected to food insecurity ". Three considerations emerge from this objective and research question: spatiotemporal analysis and targeting, development potentials, rural production systems. The various productions are also studied over a long series in order to consider the yield variations over time. Finally, these two analyzes, spatial (systems) and temporal (yields) are crossed in order to demonstrate the contribution of this decision-supporting tool in the articulation and structuring of the other two levels of targeting populations to food insecurity. The decision-supporting tool has been tested on the case study of the Nigerian population. The main outcomes are: the characterization of the opportunities and constraints of the Nigerian rural production systems; the identification of the products to be developed by production system; the identification of the most promising pathways by means of the distribution of the yields by systems. Finally, an essential point must be made about the increase of conservation methods and transformations for increasing the added value obtained by Nigerian households. At the end of this dissertation, the tool demonstrated its importance in structuring and articulating the targeting of food insecurity in the field of emergency aid and development: The territorial zones in the production systems identify the problems to which one or several solutions must be found. Production systems allow a concentration of actions according to the definition of the general and specific objectives of the agricultural development assistance programs. Potential outputs to be developed in production systems allow diversification of agriculture and structuring of development from a national point of view. The actions defined by the Technical and Financial Partners at the level of a village, a community and / or a commune can be more easily integrated into this scale of analysis and can be structured later in national development policies Agricultural policy. The increase in productivity in Niger depends on the development of products within the most favorable zones and not on the whole territory. However, this tool is complementary to the other targeting tools already in place. It should also be complemented by the same type of analysis at the level of West Africa and an analysis of the flows and prices condition to favor the flow of production. [less ▲]

Detailed reference viewed: 132 (33 ULiège)