Last 7 days
Bookmark and Share    
Full Text
See detailLe New orleans Jazz & Heritage Festival 2017
Sacré, Robert ULiege

E-print/Working paper (2017)

Compte rendu de la 48è édition du N.O. Jazz & Heritage Festival 2017 avec photos

Detailed reference viewed: 5 (0 ULiège)
See detailcrossroads, le magazine sonore du blues et des musiques américaines
Sacré, Robert ULiege

Diverse speeche and writing (2017)

Magazine sonore du Blues et des musiques américaines. Chaque mercredi de 18h à 20h; rediffusion chaque samedi de 22h à minuit. streaming: www.equinoxefm.be ; podcasts www.mixcloud.com/robertsacre9; infos ... [more ▼]

Magazine sonore du Blues et des musiques américaines. Chaque mercredi de 18h à 20h; rediffusion chaque samedi de 22h à minuit. streaming: www.equinoxefm.be ; podcasts www.mixcloud.com/robertsacre9; infos www.facebook.com/robert.sacre.9 [less ▲]

Detailed reference viewed: 28 (0 ULiège)
Full Text
Peer Reviewed
See detailSteel construction - design and research - Special issue associated to the TC11 workshop
Demonceau, Jean-François ULiege; Graziano, Leoni; Couchman, Graham et al

in Steel Construction (2017), 10

Detailed reference viewed: 13 (0 ULiège)
Full Text
Peer Reviewed
See detailPowers, abilities and skills in early modern philosophy
Boccaccini, Federico ULiege; Marmodoro, Anna

in British Journal for the History of Philosophy (2017), 25(3), 1-8

Detailed reference viewed: 30 (5 ULiège)
Full Text
See detailMental Powers in Early Modern Philosophy. Special Issue of the British Journal for the History of Philosophy
Boccaccini, Federico ULiege; Marmodoro, Anna

Book published by Routledge (2017)

Detailed reference viewed: 120 (4 ULiège)
See detailPreserving the Story of Heritage in Ruins Using Online Digital Repositories; The Case of Urbex
Eisazadeh, Negin ULiege; Bordalejo, Barbara

Conference (2017, May)

Urban explorers have for some time been producing informal iconographic and textual records of manmade structures which because of being abandoned or inaccessible for the general public, are not usually ... [more ▼]

Urban explorers have for some time been producing informal iconographic and textual records of manmade structures which because of being abandoned or inaccessible for the general public, are not usually in the public eye and are often in a state of deterioration and in danger of being destroyed. This interdisciplinary research which connects the fields of architecture, history, conservation, and digital humanities, looks into the materials recorded by the urban exploration (urbex) community and investigates their potential for the protection and documentation of decaying or demolished abandoned architectural heritage sites. For the management and dissemination of heritage information for the abandoned sites, more specifically, the recently demolished Château de Noisy, a famous urbex destination in Belgium, this study explores and builds upon the existing digital resources and looks into various tools and techniques to compile, curate and present this data to narrate the story of abandoned heritage sites. Additionally, through visualisation of data collected, cleaned, and compiled using the Flickr application programming interface (Flickr API) and Python, the changes in the urbex community’s activity since their debut on Flickr are observed. This research shows the value of the existing urbex digital data for documentation and potential conservation of abandoned heritage sites and demonstrates how a mindful digital narration of even a demolished heritage site can create an engaging and immersive experience which records and preserves the heritage and its story. Additionally, it can raise public awareness which in the case of deteriorating abandoned sites can lead to their potential revival. [less ▲]

Detailed reference viewed: 40 (5 ULiège)
Full Text
See detailLa déficience en hormone lutéinisante: ses conséquences sur la reproduction
VALDES SOCIN, Hernan Gonzalo ULiege; potorac, iulia; LIBIOULLE, Cécile ULiege et al

in Urologic (2017), 13(1), 18-23

En physiologie de la reproduction, il est bien établi que les hormones glycoprotéiques hypophysaires LH (hormone lutéinisante) et FSH régulent de concert la production de stéroïdes sexuels (indispensables ... [more ▼]

En physiologie de la reproduction, il est bien établi que les hormones glycoprotéiques hypophysaires LH (hormone lutéinisante) et FSH régulent de concert la production de stéroïdes sexuels (indispensables à la virilisation et à la féminisation) ainsi que la gamétogenèse (spermatogenèse chez l’homme et folliculogenèse chez la femme). La sécrétion des gonadotrophines hypophysaires est à son tour stimulée par quelque 1.500 neurones hypothalamiques à GnRH (gonadotrophin releasing hormone) et inhibée par la GnIH (gonadotrophin nhibitory hormone), récemment identifiée (1). En amont de la GnRH, un ensemble de neuropeptides hypothalamiques tels que les kisspeptines, la neuroquinine B, la dinorphine, la leptine, etc., modulent sa sécrétion (Figure 1). Ces neuropeptides intègrent les différents signaux internes et de l’environnement, nécessaires à la puberté et, par la suite, à la reproduction. En corollaire de ces données physiologiques, les patients porteurs de mutations invalidant les gènes de la GnRH, des neuropeptides décrits et de leurs récepteurs souffrent d’un hypogonadisme hypogonadotrope. Ces patients présentent un déficit plus ou moins sévère de la sécrétion combinée de LH et de FSH (2, 3). Il a fallu attendre des observations rares, telles que des mutations de la sous-unité beta (β) de l’hormone lutéinisante, pour comprendre la contribution spécifique et isolée de cette hormone à la reproduction. Dans cet article, nous synthétisons les données historiques et récentes sur la déficience en hormone lutéinisante et ses conséquences sur la reproduction. [less ▲]

Detailed reference viewed: 31 (9 ULiège)
Full Text
See detailRail-road terminals location with interconnected rail network of West African countries
LIHOUSSOU, Messan; Limbourg, Sabine ULiege

in Cools, Mario; Limbourg, Sabine (Eds.) Proceedings of the BIVEC-GIBET Transport Research Days 2017: Towards an Autonomous and Interconnected Transport Future (2017)

From 2006 to 2012, the port of Cotonou improves its performance thanks to the Millennium Challenge Account program, through modernization of port facilities and management systems. But the project not ... [more ▼]

From 2006 to 2012, the port of Cotonou improves its performance thanks to the Millennium Challenge Account program, through modernization of port facilities and management systems. But the project not concerns transport corridors and hinterland access. However, no port can develop without its links with its hinterland. That’s why we analyse the issues relating to the hinterland transport development with respect to the with interconnected rail network of West African countries. This network project allows us to build up a multimodal/intermodal transport network from and to the port of Cotonou since inland terminals may have an important role in enlarging port market areas through enhancing hinterland penetration capacity. Our findings show that if two rail-road terminals are located, one in Dosso and the other one in Parakou, it will allow a saving of about 112 million euro, promote local economies and sustainability. [less ▲]

Detailed reference viewed: 23 (0 ULiège)
Full Text
Peer Reviewed
See detailFrom distant neighbours to bedmates: Exploring the synergies between the social economy and sustainable development
Hudon, Marek; Huybrechts, Benjamin ULiege

in Annals of Public and Cooperative Economics (2017), 88(2), 141-154

To introduce this special issue we explore the conceptual and practical synergies between the social economy and sustainable development. New empirical evidence is presented on the emergence of these two ... [more ▼]

To introduce this special issue we explore the conceptual and practical synergies between the social economy and sustainable development. New empirical evidence is presented on the emergence of these two research fields and the increasing combination of these fields in the literature. Several avenues through which social enterprises can contribute to the transition towards sustainable development are then identified. This is followed by a discussion of how and why the combination can be particularly fruitful both for the social economy and for sustainability transition movements. We also highlight some important challenges facing the social economy with regard to its contribution to sustainable development. Finally we introduce the papers that constitute this special issue and show how they contribute, individually and collectively, to a better understanding of the increasing linkage between the social economy and sustainable development. [less ▲]

Detailed reference viewed: 79 (5 ULiège)
Full Text
Peer Reviewed
See detailCalibration and testing of wide-field UV instruments
Frey, Harald; Mende, Stephen; Loicq, Jerôme ULiege et al

in Journal of Geophysical Research. Space Physics (2017), 122

As with all optical systems the calibration of wide-field ultraviolet (UV) systems includes three main areas: sensitivity, imaging quality, and imaging capability. The one thing that makes UV calibrations ... [more ▼]

As with all optical systems the calibration of wide-field ultraviolet (UV) systems includes three main areas: sensitivity, imaging quality, and imaging capability. The one thing that makes UV calibrations difficult is the need for working in vacuum substantially extending the required time and effort compared to visible systems. In theory a ray tracing and characterization of each individual component of the optical system (mirrors, windows, and grating) should provide the transmission efficiency of the combined system. However, potentially unknown effects (contamination, misalignment, and measurement errors) can make the final error too large and unacceptable for most applications. Therefore, it is desirable to test and measure the optical properties of the whole system in vacuum and compare the overall response to the response of a calibrated photon detector. A proper comparison then allows the quantification of individual sources of uncertainty and ensures that the whole instrument performance is within acceptable tolerances or pinpoints which parts fail to meet requirements. Based on the experience with the IMAGE Spectrographic Imager, the Wide-band Imaging Camera, and the ICON Far Ultraviolet instruments, we discuss the steps and procedures for the proper radiometric sensitivity and passband calibration, spot size, imaging distortions, flatfield, and field of view determination. [less ▲]

Detailed reference viewed: 28 (4 ULiège)
Full Text
Peer Reviewed
See detailMild mitochondrial uncoupling induces HSL/ATGL-independent lipolysis relying on a form of autophagy in 3T3-L1 adipocytes
Demine, Stéphane; Tejerina, Silvia; Bihin, Benoît et al

in Journal of Cellular Physiology (2017)

Obesity is characterized by an excessive triacylglycerol accumulation in white adipocytes. Various mechanisms allowing the tight regulation of triacylglycerol storage and mobilization by lipid droplet ... [more ▼]

Obesity is characterized by an excessive triacylglycerol accumulation in white adipocytes. Various mechanisms allowing the tight regulation of triacylglycerol storage and mobilization by lipid droplet-associated proteins as well as lipolytic enzymes have been identified. Increasing energy expenditure by inducing a mild uncoupling of mitochondria in adipocytes might represent a putative interesting anti-obesity strategy as it reduces the adipose tissue triacylglycerol content (limiting alterations caused by cell hypertrophy) by stimulating lipolysis through yet unknown mechanisms, limiting the adverse effects of adipocyte hypertrophy. Herein, the molecular mechanisms involved in lipolysis induced by a mild uncoupling of mitochondria in white 3T3-L1 adipocytes were characterized. Mitochondrial uncoupling-induced lipolysis was found to be independent from canonical pathways that involve lipolytic enzymes such as HSL and ATGL. Finally, enhanced lipolysis in response to mitochondrial uncoupling relies on a form of autophagy as lipid droplets are captured by endolysosomal vesicles. This new mechanism of triacylglycerol breakdown in adipocytes exposed to mild uncoupling provides new insights on the biology of adipocytes dealing with mitochondria forced to dissipate energy. [less ▲]

Detailed reference viewed: 24 (2 ULiège)
Full Text
See detailL’INHIBITION DE LA MÉTHYLTRANSFÉRASE EZH2 DU COMPLEXE RÉPRESSEUR POLYCOMB FAVORISE LA RÉPONSE ANTI-TUMORALE DES MACROPHAGES M2 DIRIGÉE CONTRE LES CELLULES DU MÉSOTHÉLIOME PLEURAL MALIN
Hamaïdia, Malik ULiege

Doctoral thesis (2017)

Context: Malignant pleural mesothelioma (MPM) is an aggressive neoplasm affecting mesothelial cells from the pleura, pericardium and peritoneum. The disease is closely associated to asbestos exposure ... [more ▼]

Context: Malignant pleural mesothelioma (MPM) is an aggressive neoplasm affecting mesothelial cells from the pleura, pericardium and peritoneum. The disease is closely associated to asbestos exposure. Despite of rules to reduce workplace exposure to asbestos, incidence of mesothelioma is predicted to increase until 2020. Since MPM is resistant to conventional cancer therapies such as surgery, irradiation and chemotherapy, development of new options is urgently needed. In my project, I investigate the ability of immunotherapy to improve patients' outcome. My hypothesis postulates that tumor cells are tightly controlled by the immune system. In fact, clinical evidence indicates that tumor infiltration by tumor associated macrophages (TAMs) correlates with poor prognosis in malignant mesothelioma (MM). By attenuating the immune response, TAMs indeed promote survival of MM cells. TAMs share properties with alternative macrophages (M2) and are activated by anti-inflammatory (e.g. IL-10) or Th2-associated (i.e. IL-4, IL-13) cytokines. In contrast, classical (M1) macrophages are stimulated by interferon (IFN)-γ and microbial components (e.g. LPS). Aim: We hypothesized that macrophage activation is mediated by a transcriptional program tightly regulated by epigenetic modifications. We focused on the Polycomb Repressive Complex 2 (PRC2) EZH2 lysine methyltransferase responsible for trimethylation of histone H3 at lysine 27 (H3K27me3). Results: Our data show that inhibition of EZH2 reduces phagocytic activity by M2-polarised macrophages. Moreover, the cytotoxicity of supernatants conditioned by M2-macrophages is increased in presence of the EZH2 inhibitor. Finally, inhibition of EZH2 enhances the tumoricidal potential of M2 macrophages towards MM cells. We further demonstrate that macrophage killing activity requires superoxide radicals (O2.-) and peroxynitrites (ONOO-) derivatives produced by the NADPH oxidase system. Conclusion: EzH2 inhibition implements the tumoricidal potential of macrophages and may therefore improve the efficacy of immunotherapy of MM patients. [less ▲]

Detailed reference viewed: 33 (7 ULiège)
Full Text
Peer Reviewed
See detailEccentric training for tendon healing after lesion: a rat model
Kaux, Jean-François ULiege; Libertiaux, Vincent ULiege; Leprince, Pierre ULiege et al

in American Journal of Sports Medicine (2017), 45(6), 1440-1446

BACKGROUND:The tendon is a dynamic entity that remodels permanently. Platelet-rich plasma (PRP) injection has been shown to have a beneficial effect on tendon healing after lesion in rats. Furthermore ... [more ▼]

BACKGROUND:The tendon is a dynamic entity that remodels permanently. Platelet-rich plasma (PRP) injection has been shown to have a beneficial effect on tendon healing after lesion in rats. Furthermore, eccentric exercise seems to improve the mechanical quality of the tendon. HYPOTHESIS:A combination of PRP injection and eccentric training might be more effective than either treatment alone. STUDY DESIGN:Controlled laboratory study. METHODS:Adult male rats were anesthetized, an incision was performed in the middle of their left patellar tendon and an injection of physiological fluid (PF) or homologous PRP was randomly made at the lesion level. The rats were then divided into 2 groups: the eccentric group, undergoing eccentric training 3 times a week, and the untrained group, without any training. Thus, 4 groups were compared. After 5 weeks, the tendons were removed and their ultimate tensile strength and energy were measured. Tendons were frozen for proteomic analyses when all biomechanical tests were completed. Statistical analysis was performed with linear mixed effect models. RESULTS:No significant difference was found between the treatments using PF injection or PRP injection alone. However, the value of the ultimate tensile force at rupture was increased by 4.5 N (108% of control, P = .006) when eccentric training was performed. An intragroup analysis revealed that eccentric training significantly improved the ultimate force values for the PRP group. Proteomic analysis revealed that eccentric training led to an increase in abundance of several cytoskeletal proteins in the PF group, while a decrease in abundance of enzymes of the glycolytic pathway occurred in the PRP treated groups, indicating that this treatment might redirect the exercise-driven metabolic plasticity of the tendon. CONCLUSION: Eccentric training altered the metabolic plasticity of tendon and led to an improvement of injured tendon resistance regardless of the treatment injected (PF or PRP). CLINICAL RELEVANCE:This study demonstrates the necessity of eccentric rehabilitation and training in cases of tendon lesion regardless of the treatment carried out. [less ▲]

Detailed reference viewed: 72 (12 ULiège)
Full Text
Peer Reviewed
See detailIntergroup variation in robbing and bartering by long-tailed macaques at Uluwatu Temple (Bali, Indonesia)
Brotcorne, Fany ULiege; Giraud, Gwennan; Gunst, Noelle et al

in Primates : Journal of Primatology (2017)

Robbing and bartering (RB) is a behavioral practice anecdotally reported in free-ranging commensal macaques. It usually occurs in two steps: after taking inedible objects (e.g., glasses) from humans, the ... [more ▼]

Robbing and bartering (RB) is a behavioral practice anecdotally reported in free-ranging commensal macaques. It usually occurs in two steps: after taking inedible objects (e.g., glasses) from humans, the macaques appear to use them as tokens, returning them to humans in exchange for food. While extensively studied in captivity, our research is the first to investigate the object/food exchange between humans and primates in a natural setting. During a 4-month study in 2010, we used both focal and event sampling to record 201 RB events in a population of long-tailed macaques (Macaca fascicularis), including four neighboring groups ranging freely around Uluwatu Temple, Bali (Indonesia). In each group, we documented the RB frequency, prevalence and outcome, and tested the underpinning anthropogenic and demographic determinants. In line with the environmental opportunity hypothesis, we found a positive qualitative relation at the group level between time spent in tourist zones and RB frequency or prevalence. For two of the four groups, RB events were significantly more frequent when humans were more present in the environment. We also found qualitative partial support for the male-biased sex ratio hypothesis [i.e., RB was more frequent and prevalent in groups with higher ratios of (sub)adult males], whereas the group density hypothesis was not supported. This preliminary study showed that RB is a spontaneous, customary (in some groups), and enduring population-specific practice characterized by intergroup variation in Balinese macaques. As such, RB is a candidate for a new behavioral tradition in this species. [less ▲]

Detailed reference viewed: 32 (9 ULiège)
Peer Reviewed
See detailChapter 35: Immune Reconstitution and Tolerance
Belle, Ludovic ULiege; Drobyski, William R.

in Abutalib, Syed; Parameswaran, Hari (Eds.) Clinical Manual of Blood and Bone Marrow Transplantation (2017)

Hematopoietic cell transplantation (HCT) remains the only curative treatment option for many patients with hematological malignancies and genetic disorders. Recipients can receive either an autologous or ... [more ▼]

Hematopoietic cell transplantation (HCT) remains the only curative treatment option for many patients with hematological malignancies and genetic disorders. Recipients can receive either an autologous or allogeneic graft, which is often dependent upon the primary disease for which transplantation is contemplated. One of the major goals of transplantation is the development of a fully functional immune system. Patients undergoing allogeneic hematopoietic cell transplantation (alloHCT), in particular, have the highest rate of transplantrelated mortality (TRM) due to complications that can result from immunodeficiencies or immune dysregulation that occurs as a consequence of the procedure. These include, but are not limited to, infections, graft‐versus‐host disease (GvHD), autoimmune disorders, and secondary malignancies. Recovery of a fully functional immune system is thus critical for HCT success and improving immune reconstitution is of great clinical interest. This chapter will focus on immune reconstitution following allo‐HCT since immune recovery is more complicated in this setting due to the underlying HLA disparity between the donor and the recipient. [less ▲]

Detailed reference viewed: 16 (3 ULiège)
Full Text
Peer Reviewed
See detailTwo-qubit entangling gates between distant atomic qubits in a lattice
Cesa, Alexandre ULiege; Martin, John ULiege

in Physical Review A (2017), 95

Arrays of qubits encoded in the ground-state manifold of neutral atoms trapped in optical (or magnetic) lattices appear to be a promising platform for the realization of a scalable quantum computer. Two ... [more ▼]

Arrays of qubits encoded in the ground-state manifold of neutral atoms trapped in optical (or magnetic) lattices appear to be a promising platform for the realization of a scalable quantum computer. Two-qubit conditional gates between nearest-neighbor qubits in the array can be implemented by exploiting the Rydberg blockade mechanism, as was shown by D. Jaksch et al. [Phys. Rev. Lett. 85, 2208 (2000)]. However, the energy shift due to dipole-dipole interactions causing the blockade falls off rapidly with the interatomic distance, and protocols based on direct Rydberg blockade typically fail to operate between atoms separated by more than one lattice site. In this work, we propose an extension of the protocol of Jaksch et al. for controlled-Z and controlled-NOT gates which works in the general case where the qubits are not nearest neighbors in the array. Our proposal relies on the Rydberg excitation hopping along a chain of ancilla noncoding atoms connecting the qubits on which the gate is to be applied. The dependence of the gate fidelity on the number of ancilla atoms, the blockade strength, and the decay rates of the Rydberg states is investigated. A comparison between our implementation of a distant controlled-NOT gate and one based on a sequence of nearest-neighbor two-qubit gates is also provided. [less ▲]

Detailed reference viewed: 51 (12 ULiège)
Full Text
See detailEmmanuel Todd ou l'âme des peuples
Coutiez, Dimitri ULiege; Jacquemain, Marc ULiege

Article for general public (2017)

L'article expose la théorie fondamentale d'Emmanuel Todd qui défend l'influence persistante des structures familiales sur le mode d'organisation économique et politique des sociétés contemporaines. Le ... [more ▼]

L'article expose la théorie fondamentale d'Emmanuel Todd qui défend l'influence persistante des structures familiales sur le mode d'organisation économique et politique des sociétés contemporaines. Le texte montre comment le livre "Qui est Charlie" consacré à la mobilisation après les attentats contre Charlie Hebdo tout début 2015 connecte l'analyse de la conjoncture politique à la logique séculaire qu'Emmanuel Todd met en évidence dans ses travaux de démographe et d'anthropologue; [less ▲]

Detailed reference viewed: 67 (2 ULiège)
Full Text
Peer Reviewed
See detailCan any possible combination of modes improve intermodal attractiveness?
Mostert, Martine ULiege; Caris, An; Limbourg, Sabine ULiege

in Proceedings of the BIVEC-GIBET Transport Research Days 2017 (2017, May)

In its White Paper on Transport, the European Commission recognizes intermodal transport as an alternative solution to road transport. In practice, intermodal transport can be constituted by any ... [more ▼]

In its White Paper on Transport, the European Commission recognizes intermodal transport as an alternative solution to road transport. In practice, intermodal transport can be constituted by any combination of modes, while in the literature, intermodal transport is often modeled as a combination of modes in the order “road-rail/inland waterway-road”. This work develops a new intermodal allocation model which allows choosing between any direct (road, rail and inland waterways) transport and any intermodal transport chain constituted by up to three modes of transport. Intermodal solutions can pass through one or two intermodal terminals. Applied on experimental data at the European level, the model gives insight on the optimal flow distribution for economic objectives (optimization of transport operational costs) and environmental objectives (optimization of transport CO2 emissions and air pollution external costs). Results highlight that the traditional modeling of intermodal transport as a “road-rail/inland waterway-road” combination better fits economic than environmental objectives. [less ▲]

Detailed reference viewed: 20 (3 ULiège)