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See detailOpinions, attitudes et comportements politiques. Dossier de documentation
Grandjean, Geoffrey ULg

Learning material (2015)

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See detailPolitical Opinions, Attitudes and Behaviours
Grandjean, Geoffrey ULg

Learning material (2015)

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See detail18F-FPRGD2 PET/CT imaging of integrin αvβ3 in renal carcinomas: Correlation with histopathology
WITHOFS, Nadia ULg; SIGNOLLE, NICOLAS; SOMJA, Joan ULg et al

in Journal of Nuclear Medicine (The) (2015)

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See detailRésistance aux antibiotiques : le retour à l’ère prébiotique ?
Galleni, Moreno ULg; Kerff, Frédéric ULg; Rigali, Sébastien ULg

Conference (2015, February 05)

Aujourd’hui, la résistance des bactéries aux antibiotiques relève d'une préoccupation croissante dans le domaine de la santé publique et s'impose plus que jamais comme une priorité. Ce problème a un coût ... [more ▼]

Aujourd’hui, la résistance des bactéries aux antibiotiques relève d'une préoccupation croissante dans le domaine de la santé publique et s'impose plus que jamais comme une priorité. Ce problème a un coût, sociétal et économique en Europe: 25.000 décès annuels par septicémie et 1,5 milliard d’euros d’augmentation du coût des traitements. Bien que le besoin de nouveaux agents antibactériens en milieu clinique est urgent, seules deux nouvelles classes d’antibiotiques ont pu être proposées durant ces 30 dernières années. En effet, la découverte et le développement de nouveaux antibiotiques posent des défis scientifiques, cliniques et financiers importants. [less ▲]

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See detailDaily intake and bacteriological quality of meat consumed in the households of Kigali city (Rwanda)
Niyonzima, Eugène; Ongol, Martin Patrick; Kimonyo, Anasthase et al

Poster (2015, February 05)

Meat is worldwidely known to be a nutrient rich food. It provides valuable amounts of proteins,vitamins such as retinol and vitamin B12 and minerals namely iron, selenium and zinc with an increased ... [more ▼]

Meat is worldwidely known to be a nutrient rich food. It provides valuable amounts of proteins,vitamins such as retinol and vitamin B12 and minerals namely iron, selenium and zinc with an increased bioavailability than found in other dietary sources [1]. Along the production chain, meat can get contaminated by a wide range of spoilage and/or pathogenic microorganisms from the farm, slaughtering environment and distribution. The actual number of foodborne infections attributable to meat is difficult to assess accurately, principally because only a small proportion of illness cases is officially reported. However, by using outbreak data published internationally, Greig and Ravel [2] reported that 12.7 % of reported foodborne outbreaks were attributable to beef while 10.5 and 4.6 % were associated with chicken and pork, respectively. According to the same authors, Salmonella spp. and pathogenic E.coli, respectively, were identified as the causal agents in 32.9 and 34.6 % of foodborne outbreaks of bacterial origin attributable to beef. The objective of this study was to determine the meat consumption pattern in different socio-conomical categories of the population of Kigali city and to assess the bacteriological quality of the consumed meat. [less ▲]

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See detailExact and Heuristic Solution Methods for a VRP with Time Windows and Variable Service Start Time
Michelini, Stefano ULg; Arda, Yasemin ULg; Crama, Yves ULg et al

Scientific conference (2015, February 05)

We consider a VRP with time windows in which the total cost of a solution depends on the duration of the vehicle routes, and the starting time for each vehicle is a decision variable. We first develop a ... [more ▼]

We consider a VRP with time windows in which the total cost of a solution depends on the duration of the vehicle routes, and the starting time for each vehicle is a decision variable. We first develop a Branch-and-Price algorithm considering the pricing subproblem, an elementary shortest path problem with resource constraints (ESPPRC). We discuss research on this exact solution methodology, based on a bidirectional dynamic programming approach for the ESPPRC, and on the design of a matheuristic. [less ▲]

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See detailQuaternary prevention, an answer of family doctors to overmedicalization
Jamoulle, Marc ULg

in International Journal of Health Policy and Management (2015), 4((X)), 1-4

In response to the questioning of Health Policy and Management (HPAM) by colleagues on the role of rank and file family physicians in the same journal, the author, a family physician in Belgium, is trying ... [more ▼]

In response to the questioning of Health Policy and Management (HPAM) by colleagues on the role of rank and file family physicians in the same journal, the author, a family physician in Belgium, is trying to highlight the complexity and depth of the work of his colleagues and their contribution to the understanding of the organization and economy of healthcare. It addresses, in particular, the management of health elements throughout the ongoing relationship of the family doctor with his/her patients. It shows how the three dimensions of prevention, clearly included in the daily work, are complemented with the fourth dimension, quaternary prevention or prevention of medicine itself, whose understanding could help to control the economic and human costs of healthcare [less ▲]

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See detailMechanisms of metal hyperaccumulation in A. halleri
Hanikenne, Marc ULg

Scientific conference (2015, February 04)

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See detailLo “stratega” delle immagini. Cosimo I de’ Medici e gli artisti della Firenze ducale
Geremicca, Antonio ULg

Conference given outside the academic context (2015)

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See detailQui gouverne le monde ?
Santander, Sébastian ULg

Scientific conference (2015, February 04)

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See detailSite-specific height-diameter allometry of Central African moist forests
Loubota Panzou, Grâce Jopaul ULg; Doucet, Jean-Louis ULg; Fayolle, Adeline ULg

Poster (2015, February 04)

In this study we aimed to identify the variation in height-diameter allometry between forest types and among species in Central African moist forests. We also examined the consequences on biomass ... [more ▼]

In this study we aimed to identify the variation in height-diameter allometry between forest types and among species in Central African moist forests. We also examined the consequences on biomass estimation. Two forest sites in southern Cameroon with contrasting levels of deciduousness. Height and diameter were measured for a total of 521 trees belonging to 12 timber species over a large range of diameter, 10-240 cm for the Ma’an site and 11-182 cm for the Mindourou site. Non-destructive height measurements were calibrated with destructive measurements for a total of 60 trees, 30 in each site. Commercial forest inventory data (n=7253 0.5ha plots) were gathered for the Ma’an (n=34 samples and 2101 plots) and Mindourou (n=117 samples and 5152 plots) sites. A total of ten allometric models (including asymptotic and non-asymptotic models) were fitted to the height-diameter data at species (n=12) and site (n=2) level. Biomass estimates were computed based on forest inventory data and general allometric models using both site-specific and published height-diameter equations. Given the strong correlation between the non-destructive and destructive height measurements we had confidence in using the non-destructive height measurements to establish site- and species-specific height-diameter allometric equations. The height measurements performed over a wide range of diameters, 10-240 cm, tended to support an asymptotic shape (and most often the Michaelis Menten model) for the height-diameter allometry either at species and site level. We identified a significant difference in height-diameter allometry between the two study sites. For a given diameter, trees tended to be taller in the more semi-deciduous Mindourou site than in the more evergreen Ma’an site, with a maximum height of 39.5 and 46.5 m, respectively. The two sites significantly differed in stand structure and biomass. This difference is due to the variation in height-diameter allometry. Height-diameter allometry strongly varies between sites and site-specific height-diameter allometric equations should be developed to further improve the estimation of biomass and carbon stock contained in tropical forests. [less ▲]

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See detailSuppression of Limit Cycle Oscillations using the Nonlinear Tuned Vibration Absorber
Habib, Giuseppe ULg; Kerschen, Gaëtan ULg

in Proceeding IMAC XXXIII A Conference and Exposition on Structural Dynamics, Orlando 2-5 February 2015 (2015, February 03)

The objective of the present study is to mitigate, or even completely eliminate, the limit cycle oscillations in mechanical systems using a passive nonlinear absorber, termed the nonlinear tuned vibration ... [more ▼]

The objective of the present study is to mitigate, or even completely eliminate, the limit cycle oscillations in mechanical systems using a passive nonlinear absorber, termed the nonlinear tuned vibration absorber (NLTVA). An unconventional aspect of the NLTVA is that the mathematical form of its restoring force is not imposed a priori, as it is the case for most existing nonlinear absorbers. The NLTVA parameters are determined analytically using stability and bifurcation analyses, and the resulting design is validated numerically using the MATCONT software. The proposed developments are illustrated using a Van der Pol-Du ng primary system. [less ▲]

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See detailReprogramming of replication origin firing and checkpoint adaptation in adult T-cell leukemia
Carpentier, Alexandre ULg; Barez, Pierre-Yves ULg; Boxus, Mathieu et al

Conference (2015, February 03)

Human T-lymphotropic virus type 1 (HTLV-1) is a retrovirus that infects about twenty million individuals worldwide. HTLV-1 is the causative agent of different diseases among which the most common are the ... [more ▼]

Human T-lymphotropic virus type 1 (HTLV-1) is a retrovirus that infects about twenty million individuals worldwide. HTLV-1 is the causative agent of different diseases among which the most common are the adult T-cell leukemia (ATL) and a neurodegenerative disorder called HAM/TSP (Human associated myelopathy/ Tropical spastic paraparesis). A key parameter of HTLV-1 pathogenesis is faster replication of provirus-carrying lymphocytes allowing clonal expansion of infected cell populations. The virally-encoded Tax oncoprotein plays an essential role in this process by interacting with DNA replication origins and accelerating S phase progression. By reprogramming the timing of origin firing, Tax also creates a replicative stress leading to DNA double strand breaks. This mechanism further triggers the DNA damage response (DDR) that induces cell cycle arrest and initiates either apoptosis or senescence. However, HTLV-1 infected cells have developed strategies to interfere with the DDR and are adapted to checkpoint control. These cells are thus able to proliferate despite occurrence of DNA damage. Based on these observations, we now propose a novel therapeutic approach based on the principle of synthetic lethality. [less ▲]

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See detailPrésentation de cas cliniques résolus ou non résolus
WANG, François-Charles ULg

Scientific conference (2015, February 03)

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See detailEstimation of the Time Interval between the Administration of Heroin and the Sampling of Blood in Chronic Inhalers
DUBOIS, Nathalie ULg; HALLET, Claude ULg; SEIDEL, Laurence ULg et al

in Journal of Analytical Toxicology (2015)

To develop a model for estimating the time delay between last heroin consumption and blood sampling in chronic drug users. Eleven patients, all heroin inhalers undergoing detoxification, were included in ... [more ▼]

To develop a model for estimating the time delay between last heroin consumption and blood sampling in chronic drug users. Eleven patients, all heroin inhalers undergoing detoxification, were included in the study. Several plasma samples were collected during the detoxification procedure and analyzed for the heroin metabolites 6-acetylmorphine (6AM), morphine (MOR), morphine-6-glucuronide (M6G) and morphine-3-glucuronide (M3G), according to a UHPLC/MSMS method. The general linear mixed model was applied to time-related concentrations and a pragmatic four-step delay estimation approach was proposed based on the simultaneous presence of metabolites in plasma. Validation of the model was carried out using the jackknife technique on the 11 patients, and on a group of 7 test patients. Quadratic equations were derived for all metabolites except 6AM. The interval delay estimation was 2–4 days when only M3G present in plasma, 1–2 days when M6G and M3G were both present, 0–1 day when MOR, M6G and M3G were present and <2 h for all metabolites present. The ‘jackknife’ correlation between declared and actual estimated delays was 0.90. The overall precision of the delay estimates was 8–9 h. The delay between last heroin consumption and blood sampling in chronic drug users can be satisfactorily predicted from plasma heroin metabolites. [less ▲]

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See detailContribution to the Macrophytic Typology of Belgian Reference Watercourses
Galoux, Daniel; Cherot, Frédéric; Rosillon, Francis ULg et al

in Advances in Botany (2015), Volume 2015, Article ID 651369

The objective of the study is to create a typology of macrophytes for the reference watercourses of the Meuse River catchment ... [more ▼]

The objective of the study is to create a typology of macrophytes for the reference watercourses of the Meuse River catchment basininWalloniaasasteptowardstheimplementationoftheEuropeanWaterFrameworkDirective.The50sitesstudiedarethe objectofaphysicochemicalandenvironmentalcharacterizationfollowedbyafloristicsurvey(phanerogams,mosses,liverworts, andmacroalgae).Sixclustersofwatercourseswiththeircharacteristicspeciesarehighlightedbytwo-wayclusteringandindicator species. The abundance of phanerogams in some watercourses of the Arden region is not only linked to light intensity but also dependsonthedegreeofslopeandthenatureofthegeologicalsubstrate [less ▲]

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See detailThe non-convex shape of (234) Barbara, the first Barbarian
Tanga, Paolo; Carry, B.; Colas, F. et al

in Monthly Notices of the Royal Astronomical Society (2015)

Asteroid (234) Barbara is the prototype of a category of asteroids that has been shown to be extremely rich in refractory inclusions, the oldest material ever found in the Solar System. It exhibits ... [more ▼]

Asteroid (234) Barbara is the prototype of a category of asteroids that has been shown to be extremely rich in refractory inclusions, the oldest material ever found in the Solar System. It exhibits several peculiar features, most notably its polarimetric behavior. In recent years other objects sharing the same property (collectively known as ”Barbarians”) have been discovered. Interferometric observations in the mid-infrared with the ESO VLTI suggested that (234) Barbara might have a bi-lobated shape or even a large companion satellite. We use a large set of 57 optical lightcurves acquired between 1979 and 2014, together with the timings of two stellar occultations in 2009, to determine the rotation period, spin-vector coordinates, and 3-D shape of (234) Barbara, using two different shape reconstruction algorithms. By using the lightcurves combined to the results obtained from stellar occultations, we are able to show that the shape of (234) Barbara exhibits large concave areas. Possible links of the shape to the polarimetric properties and the object evolution are discussed. We also show that VLTI data can be modeled without the presence of a satellite [less ▲]

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See detailMagnetic shielding of an inhomogenous magnetic field source by a bulk superconducting tube
Hogan, Kevin ULg; Fagnard, Jean-François ULg; Wera, Laurent ULg et al

in Superconductor Science and Technology (2015), 28(3), 035011

Bulk type-II irreversible superconductors can act as excellent passive magnetic shields, with a strong attenuation of low frequency magnetic fields. Up to now, the performances of superconducting magnetic ... [more ▼]

Bulk type-II irreversible superconductors can act as excellent passive magnetic shields, with a strong attenuation of low frequency magnetic fields. Up to now, the performances of superconducting magnetic shields have mainly been studied in a homogenous magnetic field, considering only immunity problems, i.e. when the field is applied outside the tube and the inner field should ideally be zero. In this paper, we aim to investigate experimentally and numerically the magnetic response of a high-Tc bulk superconducting hollow cylinder at 77 K in an emission problem, i.e. when subjected to the non-uniform magnetic field generated by a source coil placed inside the tube. A bespoke 3-D mapping system coupled with a 3-axis Hall probe is used to measure the magnetic flux density distribution outside the superconducting magnetic shield. A finite element model is developed to understand how the magnetic field penetrates into the superconductor and how the induced superconducting shielding currents flow inside the shield in the case where the emitting coil is placed coaxially inside the tube. The finite element modelling is found to be in excellent agreement with the experimental data. Results show that a concentration of the magnetic flux lines occurs between the emitting coil and the superconducting screen. This effect is observed both with the modelling and the experiment. In the case of a long tube, we show that the main features of the field penetration in the superconducting walls can be reproduced with a simple analytical 1D model. This model is used to estimate the maximum flux density of the emitting coil that can be shielded by the superconductor. [less ▲]

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See detailDifferential Performance between Two Timber Species in Forest Logging Gaps and in Plantations in Central Africa
Fayolle, Adeline ULg; Ouedraogo, Dakis-Yaoba ULg; Ligot, Gauthier ULg et al

in Forests (2015), 6(2), 380-394

To develop silvicultural guidelines for high-value timber species of Central African moist forests, we assessed the performance of the pioneer Milicia excelsa (iroko, Moraceae), and of the non-pioneer ... [more ▼]

To develop silvicultural guidelines for high-value timber species of Central African moist forests, we assessed the performance of the pioneer Milicia excelsa (iroko, Moraceae), and of the non-pioneer light demander Pericopsis elata (assamela, Fabaceae) in logging gaps and in plantations in highly degraded areas in south-eastern Cameroon. The survival and size of each seedling was regularly monitored in the silvicultural experiments. Differences in performance and allometry were tested between species in logging gaps and in plantations. The two species performance in logging gaps was significantly different from plantations and concurred with the expectations of the performance trade-off hypothesis but not with the expectations of species light requirements. The pioneer M. excelsa survived significantly better in logging gaps while the non-pioneer P. elata grew significantly faster in plantations. The high mortality and slow growth of M. excelsa in plantations is surprising for a pioneer species but could be explained by herbivory (attacks from a gall-making psyllid). Identifying high-value native timber species (i) with good performance in plantations such as P. elata is of importance to restore degraded areas; and (ii) with good performance in logging gaps such as M. excelsa is of importance to maintain timber resources and biodiversity in production forests. [less ▲]

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See detailMBD du laboratoire à la clinique
CAVALIER, Etienne ULg

Conference (2015, February 02)

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