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See detailLa sociologie par la littérature : une approche transdisciplinaire
Ledent, David ULg

Conference (2014, November 27)

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See detailPPP in the field of employment: clandestine strategies to become an efficient PPP?
Remy, Céline ULg

Conference (2014, November 27)

In this article, we study the Public-Private Partnerships (PPP) in the field of employment, in Belgium. These PPPs are established between Public Employment Service (PES) and private operators to create ... [more ▼]

In this article, we study the Public-Private Partnerships (PPP) in the field of employment, in Belgium. These PPPs are established between Public Employment Service (PES) and private operators to create projects for support and training for jobseekers the ultimate goal of which is social and professional reintegration. There are three critical moments in the life of the partnership: getting a partnership agreement with the PES, mobilizing jobseekers to participate in the delivery, and evaluating the outcomes achieved by the operator. The parties affected by these three critical steps are mainly the private operators. To overcome these difficulties, the providers implement informal and "clandestine" strategies to ensure the proper operation of the partnership and especially its performance and sustainability. [less ▲]

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See detailAnalyse de contenu et indexation des résumés de communications des congrès CNGE Clermont 2013 et Lille 2014
Jamoulle, Marc ULg; Berkhout, Christophe

Conference (2014, November 27)

Analyse de contenu et indexation des résumés de communications des congrès CNGE Clermont 2013 et Lille 2014 Marc Jamoulle, Christoffe Berkhout Département universitaire de médecine générale. Université de ... [more ▼]

Analyse de contenu et indexation des résumés de communications des congrès CNGE Clermont 2013 et Lille 2014 Marc Jamoulle, Christoffe Berkhout Département universitaire de médecine générale. Université de Liège Département de médecine générale, Lille 2 marc.jamoulle@doct.ulg.ac.be Intro Communiquer lors d’un congrès de médecine générale représente un travail important. L’indexation de ces communications est un problème non résolu. Gérer la connaissance ainsi accumulée est un défi pour la profession de médecin de famille qui pose entre autres la question de la comparaison des résumés de communications acceptés et refusés. Méthodes L’analyse des 205 résumés de communication disponibles pour Clermont 2013 a été conduite au moyen du logiciel d’analyse qualitative ATLAS.ti. Les codes permettant d’identifier les concepts ont été choisis dans la Classification Internationale des Soins Primaires(CISP) pour les informations cliniques et dans 3CGP (Core Content Classification in GP/FM), un outil personnel de classification de l’information non clinique. L’encodage a été manuel et par un seul observateur. Les résumés du présent congrès Lille 2014 ont été mis à ma disposition au fur et à mesure de leur mise en ligne et ont été analysé de la même façon Résultats 205 résumés ont été analysés . Une première lecture des mots clefs et des résumés a permis de remettre des recommandations d’écriture avant le lancement des soumissions de Lille 2014. Les 205 résumés analysés par environ 900 items d’indexation permettent de découvrir les centres d’intérêts des médecins participants, de vérifier le bien-fondé de l’utilisation de la CISP pour indexer les résumés et d’approfondir la mise à jour de 3CGP, l’outil de classification non clinique. Au moment d’écrire ce résumé, il n’est pas possible de connaître le résultat de la comparaison entre abstracts acceptés refusés à Lille 2014. [less ▲]

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See detailRole of the polyQ length and non-polyQ regions during the aggregation process into amyloid fibrils of model polyQ proteins
Huynen, Céline ULg; Willet, Nicolas ULg; Buell, Alexander K et al

Poster (2014, November 26)

Nine neurodegenerative disorders, referred to as polyglutamine diseases and including Huntington’s disease, are associated with the abnormal expansion of a polyglutamine tract inside nine unrelated ... [more ▼]

Nine neurodegenerative disorders, referred to as polyglutamine diseases and including Huntington’s disease, are associated with the abnormal expansion of a polyglutamine tract inside nine unrelated proteins. This polyQ expansion is thought to be the major determinant in the development of neurotoxicity, triggering protein aggregation into amyloid fibrils. A large body of evidence however suggests that non-polyQ regions modulate the aggregation process triggered by polyQ expansions. The interplay between the polyQ tract and non-polyQ regions is complex and still not fully understood. In order to better understand it, we previously designed and characterized model polyQ proteins made of the beta-lactamase BlaP with 23, 30, 55 and 79Q inserted at position 197 or 216. Our first results had indicated that our model is relevant to study polyQ aggregation since it recapitulates the aggregation properties of polyQ disease-associated proteins: there is a Q-threshold for the spontaneous formation of amyloid fibrils in solution, and above the threshold, the longer the polyQ, the faster the aggregation. Moreover, the structure of BlaP and the position of insertion of the polyQ tract influence their aggregation properties in solution. This work aims to better understand, at the molecular level, (i) the precise role of the polyQ length (23, 30, 55, 61, 67, 73 and 79Q), (ii) the conformation of the host protein (native or unfolded BlaP), (iii) the location of the polyQ tract within BlaP (197 or 216), (iv) the flexibility of the polyQ flanking sequences, and (v) the origin of constraints applied by BlaP to the inserted polyQ tract (at its N- or C-terminal end) on the structural, thermodynamic and aggregation properties of BlaP-polyQ chimeras, using a wide range of biophysical techniques (e.g., spectroscopy methods, quartz crystal microbalance, atomic force microscopy and dynamic light scattering). The effect on the aggregation properties will be determined on the spontaneous aggregation into amyloid fibrils in solution, and on the nucleation and on the elongation steps of amyloid fibril formation. For this purpose, new chimeras containing 61, 67 and 73Q at position 197, or 55Q inserted at position 197 in between two different protease’s cleavage sites, that are relatively flexible, will be moreover created. Our results first demonstrate that the spontaneous aggregation into amyloid fibrils in solution is correlated to the polyQ length with an exponential growth function, and that the elongation rate is linearly correlated to the polyQ length, independently of the protein context (i.e., conformation of BlaP, and/or location of the polyQ tract, and/or polyQ peptides inserted or not within BlaP). However, the location of the polyQ tract inside BlaP, and/or its conformational state, and/or the flexibility of polyQ flanking sequences, and/or the origin of constraints applied to the polyQ tract drastically influence the ability of a polyQ tract to trigger the nucleation and/or the elongation step of amyloid fibrils (variation in the Q-threshold and in the absolute rate of both steps). Altogether, our results suggest that non-polyQ regions constitute an additional potential therapeutic target, more specific than drugs targeting the polyQ sequence, to interfere with the nucleation and/or the elongation of amyloid fibrils, associated to neurotoxicity. A possible drug could be constituted by a ligand specific to non-polyQ regions of disease-associated proteins, which further increases the constraints applied to the polyQ expansion to prevent the disease onset and/or progression. [less ▲]

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See detailClimat et gaz à effet de serre: récentes évolutions constatées
Ozer, Pierre ULg

Scientific conference (2014, November 26)

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See detailRadiotherapy : Controversy
Beckers, Albert ULg

Scientific conference (2014, November 26)

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See detailThe Eurogypsum list of biodiversity indicators: a tool to increase biodiversity capacity in the gypsum industry.
Pitz, Carline ULg; Mahy, Grégory ULg

Conference given outside the academic context (2014)

The resulting framework contains eleven indicators which are the most acceptable set of indicators for all the stakeholders. It answers to European legislation and strategies for biodiversity. It is ... [more ▼]

The resulting framework contains eleven indicators which are the most acceptable set of indicators for all the stakeholders. It answers to European legislation and strategies for biodiversity. It is intended to improve sustainability in the quarries and to help managing biodiversity, to allow setting up of appropriate reporting systems. The aim is to maintain the biodiversity status of the gypsum quarries. It is a flexible framework adaptable given the local context of each gypsum quarry in order to prove if a No Net Loss has been reached at a quarry’s scale. [less ▲]

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See detailHigh-throughput synthesis of functional oxide films
Dhanapal, Pravarthana ULg

Doctoral thesis (2014)

Epitaxy of metal oxides is of great interest since it provides a way to obtain desired novel properties for the applications such as electronics and energy. However, earlier epitaxy research's have been ... [more ▼]

Epitaxy of metal oxides is of great interest since it provides a way to obtain desired novel properties for the applications such as electronics and energy. However, earlier epitaxy research's have been restricted because of the limited range of compositions and low-index of commercially available single crystal substrates. Consequently, novel epitaxy synthesis methods need to be developed in order to go beyond the present demands of of single crystal substrates in terms of phase, composition, size, orientation and symmetry. In this research work, we have developed a high-throughput synthesis process, called combinatorial substrate epitaxy (CSE), where an oxide film is grown epitaxially on a polycrystalline substrate. As a proof-of-concept, we firstly fabricated Ca3Co4O9 films on Al2O3 ceramics. Films have a good local epitaxial registry, and the Seebeck coefficient is about 170 µV/K at 300 K. High quality BiFeO3/La0.7Sr0.3MnO3 thin film heterostructures were secondly deposited on dense LaAlO3 ceramics prepared by spark plasma sintering. Piezoforce microscopy was used to confirm the local ferroelectric properties. Thirdly, we investigate the growth of of metastable monoclinic Dy2Ti2O7 epitaxial films on polycrystalline La2Ti2O7 substrates. We conclude that CSE approach opens the way towards unexpected electronic properties in oxide films. [less ▲]

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See detailPattern Matching & Image Registration
Latour, Philippe ULg

Learning material (2014)

This document is an overwiew of the objectives, methods and applications of pattern matching and image registration. Both pixel-based and features-based methods are reviewed and compared. Some ... [more ▼]

This document is an overwiew of the objectives, methods and applications of pattern matching and image registration. Both pixel-based and features-based methods are reviewed and compared. Some applications to machine vision (electronic component manufacturing) are described. [less ▲]

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See detailAllergies alimentaires
GADISSEUR, Romy ULg

Conference (2014, November 26)

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See detailIn vitro hemocompatibility assessment of Near-IR-Emitting Ag2S Quantum Dots (QD)
Grandfils, Christian ULg; Hocaoglu, I.; Demir, F. et al

in Proceeding of the Nanobiotechnology International Workshop (2014, November 26)

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See detailPrésentation de Chr. Puren et mise en perspective de sa conférence
Simons, Germain ULg

Speech/Talk (2014)

Brève introduction de la conférence de Chr. Puren intitulée "Genre, CECRL et perspective de l'agir social". Chr. Puren a d'abord été brièvement présenté, puis la problématique des "genres textuels" dans ... [more ▼]

Brève introduction de la conférence de Chr. Puren intitulée "Genre, CECRL et perspective de l'agir social". Chr. Puren a d'abord été brièvement présenté, puis la problématique des "genres textuels" dans le CECRL a été mise en perspective et reliée aux deux journées d'études "Questions de genres" organisées en avril 2014 par l'Entité de recherche structurelle Langues et littératures modernes. [less ▲]

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See detailUse of 13C-NMR in structural elucidation of polysaccharides: case of locust bean gum
Gillet, Sébastien ULg; Aguedo, Mario ULg; Blecker, Christophe ULg et al

Poster (2014, November 25)

Locust bean gum (LBG) galactomannans are polysaccharides consisting of a β-(1→4) D-mannopyranosyl backbone substituted to varying degrees in α-(1→6) with single D-galactopyranosyl residues. This basic ... [more ▼]

Locust bean gum (LBG) galactomannans are polysaccharides consisting of a β-(1→4) D-mannopyranosyl backbone substituted to varying degrees in α-(1→6) with single D-galactopyranosyl residues. This basic structure is the same for all galactomannans (Fig. 2). However, when locust bean gum is extracted at different temperatures, the generated fractions exhibit different properties in aqueous solution (viscosity, viscoelasticity, gel formation, thermohydrolysis resistance, etc.). This means that there are differences within the fine structure of the polymers (although the basic structure is the same). Analysis of [13C]-NMR spectra of galactomannans, in combination with other techniques, can provide capital information about fine structural elucidation of the polymers. The method specifies the distribution of lateral galactosyls along the main chain of mannans. Two fractions extracted from locust bean gum at 25 and 80 °C (respectively GM25 and GM80) were comparatively studied by [13C]-NMR. Mannosyls/Galactosyls (M/G) ratios can be determined by considering the intensities of C-1 mannose and galactose signals in [13C]-NMR spectra. This method provides results relatively close to those obtained by GC-MS analysis. Spectra also showed that resonance from C4 of D-mannose residues were split, in evident dependence upon the nearest-neighbor probabilities (“diad frequencies”) of D-galactosyl groups along the mannan chains (Fig. 2). Diad frequencies were obtained by integrating C4(Man) peak areas. F11, F21/F12 and F22 gave respectively the di-, mono- or non-substituted mannose pairs proportions. High percentages of F11 and F22 therefore indicate a more non-homogeneous distribution of lateral galactosyls along the polysaccharide backbone as observed for GM80. The percentages of total lateral substituents obtained by C4(Man) peak analysis [F11 + (F21 or F12)/2] were fairly well correlated with M/G ratios. Splitting of the C-6 substituted D-mannose resonance provides, therefore the basis for determining the next-nearest-neighbor probabilities (triad frequencies) (Fig. 2). However, the spectrum is often not sufficiently resolved to accurately quantify and interpret the results. [less ▲]

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See detailGuides d'architecture moderne et contemporaine en Wallonie et à Bruxelles
Charlier, Sébastien ULg; Moor, Thomas

Conference (2014, November 25)

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See detailEgyptian Gods in Graeco-Roman Context. II. Playing, singing and dancing for Isis.
Veymiers, Richard ULg

Scientific conference (2014, November 25)

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