Last 7 days
Bookmark and Share    
See detailLe statut du chercheur comme acteur de l'institution, comme chercheur et comme travailleur
Cormann, Grégory ULg

Diverse speeche and writing (2014)

Detailed reference viewed: 12 (3 ULg)
See detailIntermediaries, transport costs and interlinked transaction
Tharakan, Joseph ULg

Conference (2014, April 29)

Detailed reference viewed: 8 (1 ULg)
See detailMultiscale modelling of angiogenesis during normal and impaired bone regeneration
Carlier, Aurélie ULg

Doctoral thesis (2014)

Bone regeneration is, like many other healing events, a complex, well-orchestrated process involving a myriad of different cell types and regulated by countless biochemical, physical and mechanical ... [more ▼]

Bone regeneration is, like many other healing events, a complex, well-orchestrated process involving a myriad of different cell types and regulated by countless biochemical, physical and mechanical factors. But unlike other adult biological tissues, the majority of bone fractures can heal without the production of scar tissue, eventually recovering the original bone shape, size and strength. Despite bone’s remarkable healing capacity and the continuing research efforts, the impaired healing of complex orthopaedic cases is still not fully understood. This PhD work hypothesises that computational modelling can make a substantial contribution to the bone regeneration field by proposing and testing the underlying mechanisms of action as well as by designing and optimising experimental strategies in silico. In the first part of this work, an existing bioregulatory model of fracture healing is extended with an intracellular module of Dll4-Notch1 signalling in order to capture the ingrowth of new blood vessels through sprouting angiogenesis. The predictions of the new MOSAIC model are compared to experimental results and an extensive sensitivity analysis is performed on the newly introduced parameters. The potential of the MOSAIC model to investigate the influence of the molecular mechanisms on angiogenesis and consequently the bone formation process is illustrated. In the second part of this work, the MOSAIC model is further improved with a rigorous implementation of the influence of oxygen on the behaviour of skeletal cells. A comprehensive literature study is performed in order to ensure the correspondence of the oxygen ranges of the cell-specific oxygen-dependent processes with the state-of-the-art experimental knowledge. The oxygen model is corroborated with previously published experimental results. The robustness of the oxygen model with respect to the newly introduced oxygen thresholds is demonstrated by a sensitivity analysis. Some limitations and shortcomings of the oxygen model are identified together with suggestions for future work. In the last part of this work, the added value of the oxygen model is shown by applying it to three cases of impaired bone healing: the occurrence of nonunions in critical size defects, bone graft healing in a compromised environment and the impaired healing of bone fractures in NF1 patients. Not only is the oxygen model used to determine the underlying mechanisms of action, potential treatment strategies for the respective challenging orthopaedic conditions are also designed and optimised in silico. In conclusion, this PhD thesis demonstrates the potential of an integrative in vivo-in silico approach to advance our current understanding of bone regeneration as well as to design effective treatments of complex bone fractures. [less ▲]

Detailed reference viewed: 20 (4 ULg)
Full Text
See detailQuasi-periodic flares in Jupiter's aurora : new results
Bonfond, Bertrand ULg; Grodent, Denis ULg; Badman, Sarah et al

Conference (2014, April 29)

Two recent Hubble Space Telescope observation campaigns have been dedicated to the Jovian Far-UV aurora (GO 12883 – PI: D. Grodent and GO 13035 – PI: S. Badman). Both of them made use of the Time-Tag mode ... [more ▼]

Two recent Hubble Space Telescope observation campaigns have been dedicated to the Jovian Far-UV aurora (GO 12883 – PI: D. Grodent and GO 13035 – PI: S. Badman). Both of them made use of the Time-Tag mode of the Space Telescope Imaging Spectrograph (STIS), a high time resolution mode which allows to observe temporal variations on timescales of tens of seconds. In the present study, we focus on sudden and spectacular bursts of auroral emissions taking place in the active region located poleward of the main emissions and called “flares”. A previous study, based on only two image sequences acquired with rather unfavorable viewing angles, showed that these flares could reappear quasi-periodically on time scales of 2-3 minutes. Phenomena with similar timescales have been identified by in-situ spacecraft in relativistic electron and radio data as well as in reconnection signatures, for example. But the physical mechanism behind these ubiquitous signatures remains to be unveiled. Here we make use of the most recent and much larger data set to study in further details the occurrence rate, the period, the location, the extent and the motion of these quasi-periodic flares and to compare their behavior in both hemispheres. Quantifying these parameters allows us to narrow down the possibilities among likely explanations and provide a tentative scenario for these short timescale quasi-periodic features. [less ▲]

Detailed reference viewed: 11 (2 ULg)
Full Text
See detailCode du développement territorial et politique foncière
Fontaine, Pierre; Halleux, Jean-Marie ULg

Conference (2014, April 28)

Detailed reference viewed: 14 (2 ULg)
Full Text
See detailMuti-scale methods with strain-softening: damage-enhanced MFH for composite materials and computational homogenization for cellular materials with micro-buckling
Wu, Ling ULg; Nguyen, Van Dung ULg; Doghri, Issam et al

Scientific conference (2014, April 28)

Materials used in the aerospace industry, as composite or foamed materials are multiscale in nature. To predict the macroscopic behaviour of structures made of such materials, the micro-scopic responses ... [more ▼]

Materials used in the aerospace industry, as composite or foamed materials are multiscale in nature. To predict the macroscopic behaviour of structures made of such materials, the micro-scopic responses should also be computed within a nested scheme. This is particularly true when non-linear behaviours are modelled, or when the failure and post failure analyses are sought. In this work, multi-scale methods with strain softening are developed in the contexts of damage modelling for composite laminates and of buckling analyses in cellular materials. First, an anisotropic gradient–enhanced continuum damage model is embedded in a mean–field homogenization (MFH) process for elasto-plastic composites. The homogenization procedure is based on the newly developed incremental secant mean-field homogenization formulation, for which the residual stress and strain states reached in the phases upon a fictitious elastic unloading are considered as starting point to apply the secant method. The mean stress fields in the phases are then computed using isotropic secant tensors, which are naturally used to define the Linear Comparison–Composite The resulting multi– scale model is then applied to study the damage process at the meso–scale of laminates, and in particular the damaging of plies in a composite stack. By using the gradient–enhanced continuum damage model, the problem of losing uniqueness upon strain softening is avoided. Second, an efficient multi–scale finite element framework capturing the buckling instabilities in cellular materials is developed. As a classical multi–scale computational homogenization scheme loses accuracy with the apparition of the macroscopic localizations resulting from the micro–buckling, the second order multi–scale computational homogenization scheme is considered. This second–order computational framework is enhanced with the following novelties so that it can be used for cellular materials. At the microscopic scale, the periodic boundary condition is used because of its efficiency. As the meshes generated from cellular materials exhibit a large void part on the boundaries and are not conforming in general, the classical enforcement based on the matching nodes cannot be applied. A new method based on the polynomial interpolation2 without the requirement of the matching mesh condition on opposite boundaries of the representative volume element (RVE) is developed. Next, in order to solve the underlying macroscopic Mindlin strain gradient continuum of this second–order scheme by the displacement–based finite element framework, the treatment of high order terms is based on the discontinuous Galerkin (DG) method to weakly impose the C1-continuity. Finally, as the instability phenomena are considered at both scales of the cellular materials, the path following technique is adopted to solve both the macroscopic and microscopic problems. [less ▲]

Detailed reference viewed: 23 (8 ULg)
Full Text
Peer Reviewed
See detailLong-wave infrared digital holographic interferometry with diffuser or point source illuminations for measuring deformations of aspheric mirrors
Vandenrijt, Jean-François ULg; Thizy, Cédric ULg; Queeckers, Patrick et al

in Optical Engineering : The Journal of the Society of Photo-Optical Instrumentation Engineers (2014), 53(11), 112309

Long-wave infrared digital holographic interferometry with CO2 laser and microbolometer arrays has been developed for testing the large deformations of space reflectors. The setup considered is a ... [more ▼]

Long-wave infrared digital holographic interferometry with CO2 laser and microbolometer arrays has been developed for testing the large deformations of space reflectors. The setup considered is a Mach–Zehnder, associated to the digital holography reconstruction of the wavefront in the inline configuration with phase shifting. Two possibilities exist for illuminating the tested reflector: either with a point source (similarly to classical interferometry) or an extended source (with a diffuser). This paper presents the development of a modular setup which allows comparing both in the case of a parabolic mirror [less ▲]

Detailed reference viewed: 20 (2 ULg)
Full Text
See detailTentatives de réflexion sémiotique et psychanalytique au sujet du voile islamique
Demoulin, Laurent ULg

E-print/Working paper (2014)

La sémiotique et la psychanalyse sont peut-être de nature à enrichir le débat sur l'interdiction du voile islamique dans les lieux publics.

Detailed reference viewed: 15 (4 ULg)
Full Text
See detailThermal tracer tests for characterizing a shallow alluvial aquifer
Wildemeersch, Samuel ULg; Klepikova, Maria ULg; Jamin, Pierre ULg et al

in Geophysical Research Abstracts (2014, April 28)

Using heat as an active tracer in different types of aquifers is a topic of increasing interest [e.g. Vandenbohede et al.; 2008, Wagner et al., 2013; Read et al., 2013]. In this study, we investigate the ... [more ▼]

Using heat as an active tracer in different types of aquifers is a topic of increasing interest [e.g. Vandenbohede et al.; 2008, Wagner et al., 2013; Read et al., 2013]. In this study, we investigate the potential interest of coupling heat and solute tracer tests for characterization of a shallow alluvial aquifer. A thermal tracer test was conducted in the alluvial aquifer of the Meuse River, Belgium. The tracing experiment consisted in simultaneously injecting heated water and a dye tracer in a piezometer and monitoring the evolution of groundwater temperature and tracer concentration in the recovery well and in nine monitoring wells located according to three transects with regards to the main groundwater flow direction. The breakthrough curves measured in the recovery well showed that heat transfer in the alluvial aquifer is slower and more dispersive than solute transport. Recovery is very low for heat while in the same time it is measured as relatively high for the solute tracer. This is due to the fact that heat diffusion is larger than molecular diffusion, implying that exchange between groundwater and the porous medium matrix is far more significant for heat than for solute tracers. Temperature and concentrations in the recovery well are then used for estimating the specific heat capacity with the energy balance approach and the estimated value is found to be consistent with those found in the literature. Temperature breakthrough curves in other piezometers are contrasted with what would be expected in an ideal layered aquifer. They reveal strongly unequal lateral and vertical components of the transport mechanisms. By means of a numerical heat transport model, we provide a preliminary interpretation of these temperature breakthrough curves. Furthermore, these data could be included in the calibration of a complex heat transfer model for estimating the entire set of heat transfer parameters and their spatial distribution by inverse modeling. [less ▲]

Detailed reference viewed: 7 (0 ULg)
Full Text
See detailApplication of multiple-point geostatistics on modelling pumping tests and tracer tests in heterogeneous environments with complex geological structures
Huysmans, Marijke; Dassargues, Alain ULg

in Geophysical Research Abstracts (2014, April 28)

In heterogeneous environments with complex geological structures, analysis of pumping and tracer tests is often problematic. Standard interpretation methods do not account for heterogeneity or simulate ... [more ▼]

In heterogeneous environments with complex geological structures, analysis of pumping and tracer tests is often problematic. Standard interpretation methods do not account for heterogeneity or simulate this heterogeneity introducing empirical zonation of the calibrated parameters or using variogram-based geostatistical techniques that are often not able to describe realistic heterogeneity in complex geological environments where e.g. sedimentary structures, multi-facies deposits, structures with large connectivity or curvi-linear structures can be present. Multiple-point geostatistics aims to overcome the limitations of the variogram and can be applied in different research domains to simulate heterogeneity in complex environments. In this project, multiple-point geostatistics is applied to the interpretation of pumping tests and a tracer test in an actual case of a sandy heterogeneous aquifer. This study allows to deduce the main advantages and disadvantages of this technique compared to variogram-based techniques for interpretation of pumping tests and tracer tests. A pumping test and a tracer test were performed in the same sandbar deposit consisting of cross-bedded units composed of materials with different grain sizes and hydraulic conductivities. The pumping test and the tracer test are analyzed with a local 3D groundwater model in which fine-scale sedimentary heterogeneity is modelled using multiple-point geostatistics. To reduce CPU and RAM requirements of the multiple-point geostatistical simulation steps, edge properties indicating the presence of irregularly-shaped surfaces are directly simulated. Results show that for the pumping test as well as for the tracer test, incorporating heterogeneity results in a better fit between observed and calculated drawdowns/concentrations. The improvement of the fit is however not as large as expected. In this paper, the reasons for these somewhat unsatisfactory results are explored and recommendations for future applications of multiple-point geostatistics on pumping tests and tracer tests are formulated. [less ▲]

Detailed reference viewed: 7 (0 ULg)
See detailThe last Neandertals and the Middle to Upper Paleolithic transition in Europe
Flas, Damien ULg

Scientific conference (2014, April 28)

Detailed reference viewed: 17 (0 ULg)
Peer Reviewed
See detailContribution of a new active faults map and sedimentary cores to the characterization of seismogenic sources in an interdisciplinary approach (Western Gulf of Corinth, Greece)
Beckers, Arnaud ULg; Hubert, Aurelia ULg; Beck, Christian et al

Conference (2014, April 28)

The Corinth rift is one of the fastest spreading rifts on Earth. 5 earthquakes of magnitude greater than 5.8 occurred during the last 40 years. The question of seismic hazard is consequently particularly ... [more ▼]

The Corinth rift is one of the fastest spreading rifts on Earth. 5 earthquakes of magnitude greater than 5.8 occurred during the last 40 years. The question of seismic hazard is consequently particularly relevant. Despite a long earthquake catalogue, estimations of earthquake hazard remain problematic because of the difficulty to associate each historical event to one of the many active faults mapped in the area. Consequently, combining seismology, history and paleoseismology in an interdisciplinary approach is here necessary and is the goal of the ANR-SISCOR project. In this framework, we investigated the offshore sediments in order to (1) better constraint the length of the active offshore faults, and (2) look for sedimentary signature of historical earthquakes. 600 km of high resolution seismic reflexion data have been acquired during two surveys and 12 short gravity cores have been retrieved. The latters are 0.5 to 1 m long, allowing us to analyze about 500 yrs of sedimentation. Two new faults potentially able to trigger M>5.5 earthquakes have been mapped in the northern part of the gulf based on seismic data. Sedimentary events (turbidites and mud flows) have been identified in some cores, essentially in the deep basin and in a 180m-deep sub-basin close to the northern coast. The comparison with the critically reviewed historical records shows that some of these events could have been triggered by historical earthquakes. The link between these potential earthquakes sedimentary signatures, historical events and active faults is discussed based on intensity maps and our new active fault map. [less ▲]

Detailed reference viewed: 40 (3 ULg)
Full Text
See detailControl of attosecond electronic dynamics in molecules
Mignolet, Benoît ULg

Doctoral thesis (2014)

Detailed reference viewed: 16 (9 ULg)
Full Text
See detailCharcoal records reveal past occurrences of perturbations in the forests of the Kisangani region(RDC): vegetation history of the semi-deciduous rainforest
Tshibamba Mukendi, John; Hubau, Wannes; Morin-Rivat, Julie ULg et al

Poster (2014, April 28)

Introduction. Past disturbances have modified the structure and the floristic composition of Central African rainforests. These perturbations represent a driving force for forest dynamics and they are ... [more ▼]

Introduction. Past disturbances have modified the structure and the floristic composition of Central African rainforests. These perturbations represent a driving force for forest dynamics and they are presumably at the origin of present-day forest mosaics. Fire is a prominent forest disturbance, leaving behind charcoal as a witness of past forest dynamics. The question arises whether quantification, dating and botanical identification of ancient charcoal fragments found in soil layers (pedoanthracology) allows a detailed reconstruction of forest history, including the possible occurrence of past disturbances. Material & methods. We organized pedoanthracological excavations in 6 regrowth sites and 48 sites of primary forests of Yangambi, Yoko, Masako and Kole in the Kisangani (RDC). We performed a detailed sampling in different vegetation types of a semi -deciduous rainforest (Yoko). Charcoal sampling was conducted in pit intervals of 10 cm. The charcoal was quantified whereby pottery fragments were also registered. A selection of charcoal fragments has been dated through AMS 14C measurement. Floristic identifications were conducted using. former protocols based on wood anatomy, which is largely preserved after charcoalification. Results. Charcoal was found in most pit intervals. The anthracomass in the soil of regrowth forests (secondary forests) is much higher than in the primary forest: 27,59 mg/kg for secondary forests et 2,53 mg/kg for primary forests. The specific soil anthracomass of the primary forest of the Yoko reserve is higher (7,7 mg/kg) than in Yangambi (1,9 mg/kg) , Masako (1,7 mg/kg) and Kole (0,8 mg/kg). No systematic differences have been found between soil charcoal content of the different forest type representing different forest histories. Gilbertiodendron dewevrei (De Wild.) J. Leonard forests showed surprisingly a higher concentration of soil charcoal. Discussion. Forest disturbances in the Kisangani region appear to be more recent than those in the Mayombe forest in Western RDC ( 3000-2000 calBP (Hubau, 2013)) and those of the Cameroon forest (2300-1300 calBP) (Morin-Rivat, J et al., 2014). Stratified charcoal conserved in the soil is a useful indicator of past forest disturbances. [less ▲]

Detailed reference viewed: 69 (4 ULg)
Full Text
See detailDioxin Analyses. The Dogs Bark, but the Caravan Goes on...
Focant, Jean-François ULg

Scientific conference (2014, April 28)

Detailed reference viewed: 15 (3 ULg)
Full Text
See detailApplication of multi-scale variography for inferring the spatial variability of the hydraulic conductivity of a sandy aquifer
Rogiers, Bart; Vienken, Thomas; Gedeon, M et al

Poster (2014, April 28)

In the framework of the disposal of short-lived low- and intermediate-level radioactive waste in a near-surface disposal facility in Dessel (Belgium), extensive characterization of the hydraulic ... [more ▼]

In the framework of the disposal of short-lived low- and intermediate-level radioactive waste in a near-surface disposal facility in Dessel (Belgium), extensive characterization of the hydraulic conductivity (K) in the shallow Neogene aquifer has been performed at a regional scale. In the last few years the small-scale heterogeneity has been additionally characterized by outcrop analogue, hydraulic direct push, and borehole core air permeameter studies. The gathered data now include a) more than 350 hydraulic conductivity measurements on samples from 8 cored boreholes, mostly reaching depths of 50 m and data at 2 m intervals, b) more than 5000 air permeability measurements on the same borehole cores, c) more than 250 cone penetration tests (CPTs) with depths down to 40 m and data at 2 cm intervals, d) over 100 dissipation tests performed during the CPT campaigns, e) 17 direct push injections loggings, 6 hydraulic profiling tool logs, and 6 direct push slug tests, f) several hundreds of air permeability measurements on outcrop analogues of the aquifer sediments, and g) numerous grain size analyses. The current study aims to quantify the heterogeneity of K from the centimetre- to the kilometre-scale and to check the compatibility of the spatial variability revealed by the different datasets. This is achieved through gathering all K values (either direct measurements, calibrated relative K values, or K estimates from secondary data), and the use of variography to quantify spatial variability in terms of two-points geostatistics. The results are discussed, and the main differences between the different data sources are explained. In a final step, different multi-scale variogram models are proposed for capturing the main characteristics of multi-scale variability within the shallow Neogene aquifer in Belgium. [less ▲]

Detailed reference viewed: 19 (3 ULg)
Full Text
See detailThe age of river-transported carbon: new data from African catchments and a global perspective
Marwick, TR; Tamooh, F; Teodoru, C et al

Conference (2014, April 27)

Detailed reference viewed: 10 (1 ULg)