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See detailPanel “Quand la bande dessinée se reproduit : imitation, reprise et rétro-réflexivité”
Crucifix, Benoît ULiege; Busi-Rizzi, Giorgio

Diverse speeche and writing (2017)

Co-organisation et présidence du panel "Quand la bande dessinée se reproduit : imitation, reprise et rétro-réflexivité" – Dans une industrie culturelle basée sur les principes de série et d’imitation, les ... [more ▼]

Co-organisation et présidence du panel "Quand la bande dessinée se reproduit : imitation, reprise et rétro-réflexivité" – Dans une industrie culturelle basée sur les principes de série et d’imitation, les questions de reproduction occupent une place toute particulière, illustrée par ce terme spécifique de swipe utilisé dans l’industrie du comic book. L’imitation s’est instituée comme principe éditorial autant dans la bande dessinée nord-américaine que dans la bande dessinée franco-belge : le style graphique se constitue ainsi souvent par imitation et reproduction, comme le montre l’exemple de l’émulation des styles ‘singuliers’ d’artistes tels que Jack Kirby ou André Franquin. Les rééditions des œuvres du passé tout comme les reprises de série classique s’épanouissent aujourd’hui et, simultanément, la bande dessinée s’empare de plus en plus de son propre passé, invoquant les connaissances encyclopédiques de ses lecteurs et s’engageant dans une forme de « rétro-réflexivité » (Brett Camper). Ces pratiques de reproduction par imitation indiquent différentes manières de penser la mise-à-disposition du passé dans le présent. Elles négocient ainsi de façon spécifique et historique le rapport à la reproductibilité en bande dessinée, par le biais de diverses techniques (recopiage, décalquage, collage, dessin, détournement, réinterprétation graphique, photocopie, clins d’œil, copier/coller, etc.) : à chaque fois, elles semblent alors interroger le rapport entre dessin et reproduction, que celle-ci soit manuelle, mécanique ou numérique. Cette session portera sur la prégnance de la reproduction par imitation dans la bande dessinée afin d’en examiner les enjeux culturels et esthétiques qui la lient à son passé et à son histoire. Comment la bande dessinée se reproduit-elle elle-même ? Quelles sont les pratiques de citation qui lui sont propres ? Comment ce rapport au passé a-t-il changé ? [less ▲]

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See detailNon-pathological aging of the executive functions: influence of the Val108/158Met nucleotide polymorphism of the COMT gene
Gilsoul, Jessica ULiege; Manard, Marine ULiege; Collette, Fabienne ULiege

Poster (2017, July 13)

Objectives. The aim of the study is to investigate the influence of the COMT Val108/158Met nucleotide polymorphism, associated with dopaminergic regulation, on executive functions in normal aging. Indeed ... [more ▼]

Objectives. The aim of the study is to investigate the influence of the COMT Val108/158Met nucleotide polymorphism, associated with dopaminergic regulation, on executive functions in normal aging. Indeed, according to the Dual-State Theory, Val/Val polymorphism of the COMT gene would favor better flexibility abilities, whereas Met/Met carriers would favor better stability abilities. These genotypic effects should be magnified in older people, as a decrease in cognitive resources increases the influence of individual genetic differences on cognitive performance. Method. We assessed the executive processes of inhibition, shifting, and updating – thanks to many different tasks in groups of young (n = 55) and aged participants (n = 45) carrying one of the three polymorphism of the COMT gene (Val/Val, Val/Met, Met/Met). T-tests between our two groups (Young versus Aged) but also a 6 (Group: Young-Met/Met, Young-Val/Met, Young- Val/Val, Old-Met/Met, Old-Val/Met, and Old-Val/Val) X 3 (Executive functioning: Inhibition, Shifting, and Updating) repeated measure ANOVA with Executive functioning as within-subject factor (p < .05) were carried out. Results. Young and old participants significantly differed on the three executive functions. The comparison of genotypic groups showed no significant differences in young or older participants respectively. Interestingly, the Old-Val/Val group showed a lower performance than the young one on inhibition tasks. Conclusion. As expected, we found an age effect on all the executive functions. The significant difference between the Young-Val/Val and the Old-Val/Val groups on inhibition suggests an age-related decrease in abilities requiring a stability component in individuals possessing a less favoring genotype for this component. [less ▲]

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See detailPrésidence de la session "Réappropriations: recyclages, effacements, détournements"
Delville, Michel ULiege

Diverse speeche and writing (2017)

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See detailStability of pentaquarks with a two- plus three-body chromoelectric interaction
Stancu, Floarea ULiege

in Physical Review. D : Particles and Fields (2017), 96

We study the stability of pentaquarks within a schematic model based on SU(3) color symmetry, by taking into account algebraic arguments leading to a chromoelectric interaction containing two- and three ... [more ▼]

We study the stability of pentaquarks within a schematic model based on SU(3) color symmetry, by taking into account algebraic arguments leading to a chromoelectric interaction containing two- and three-body parts. It has already been proven that such an interaction can influence the spectrum of ordinary baryons and the stability of tetraquarks and hexaquarks. Here we discuss its role in the stability of pentaquarks against strong decays. [less ▲]

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See detailEffect of surface modification of polylactides on fibroblasts L-929 and osteoblasts MG-63
Tilkin, Rémi ULiege; Regibeau, Nicolas ULiege; Lambert, Stéphanie ULiege et al

Conference (2017, July 12)

During the past few years, tissue engineering has become one of the most promising techniques to maintain, improve, or reconstruct human tissue, even complete human organs. This solution is frequently ... [more ▼]

During the past few years, tissue engineering has become one of the most promising techniques to maintain, improve, or reconstruct human tissue, even complete human organs. This solution is frequently based on the realization of temporary porous matrices, also called "scaffolds", design as model and structure for the development of cells. Surface properties of those biomaterials are some determinant criteria for cell adhesion and proliferation. The scope of this work is the study of adhesion and proliferation of fibroblasts L-929 and osteoblasts MG-63 on untreated, hydrolyzed or aminolyzed polylactides. First, these substrates are developed: poly-L,D-lactide (PDLLA) powder is pressed into disks. The surface of disks was chemically modified by hydrolysis and aminolysis surface treatments. Surface modifications were based on previous studies. [1,2] The hydrolysis process is carried out by immersing PDLLA disks in 2 M NaOH for 20 min at room temperature (24°C) under constant agitation. The aminolysis process is performed by placing PDLLA disks in 15 % ethylenediamine in isopropanol for 5 min at room temperature (24°C) under constant agitation. Substrates are characterized by optical microscopy, Scanning Electron Microscopy and water contact angle. Finally, cell adhesion, proliferation, and viability on these substrates are assessed by cell counting and MTT assay after 1, 4, and 8 days of cell culture. Results from surface characterization show an increase of roughness for hydrolyzed polylactide. Regarding water contact angle measurements, values are smaller on treated substrates even though the difference with untreated substrates appears smaller than expected in the literature. [1,2] Cell counting and MTT assay show an increase of cell proliferation and cell viability for treated polylactide substrates in the case of fibroblasts and a decrease of cell proliferation for aminolyzed polylactide substrates in the case of osteoblasts. In conclusions, this work highlights the different effects of surface modification on fibroblasts and osteoblasts viability. References : [1]. Wang YQ, Cai JY. Enhanced cell affinity of poly(L-lactic acid) modified by base hydrolysis: wettability and surface roughness at nanometer scale. Current Applied Physics 2007, 7(S1):e108–e111. [2]. Lin Y, Chrzanowski W, Knowles J, Bishop A, Bismarck A. Functionalized poly(D,L-lactide) for pulmonary epithelial cell culture. Advanced Engineering Materials 2010, 12(4): B101–B112. [less ▲]

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See detailAdvanced oxidative treatment for waste water contaminated by pharmaceutical products
Wolfs, Cédric ULiege; Vreuls, Christelle; Gillard, Nathalie et al

Conference (2017, July 12)

The objective of this study is to determine operational processes for advanced oxidative treatment of waste waters contaminated with pharmaceutical products. The aim is to validate a physico-chemical ... [more ▼]

The objective of this study is to determine operational processes for advanced oxidative treatment of waste waters contaminated with pharmaceutical products. The aim is to validate a physico-chemical process that has to be placed downstream a classical biological treatment in existing waste water treatment plants (domestic, industrial or hospital). [less ▲]

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See detailDistributions of urban geometric attributes: a stochastic Muth-Mills approach
Delloye, Justin; Peeters, Dominique; Tharakan, Joseph ULiege

Conference (2017, July 12)

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See detailPlus oultre la succession politique. Étude cérémonielle de l’abdication de Charles Quint
Goderniaux, Alexandre ULiege

Conference given outside the academic context (2017)

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See detailMapping the diachrony of content words: Ancient Greek and Ancient Egyptian as sources for diachronic semantic maps of lexical items
Georgakopoulos, Athanasios ULiege; Polis, Stéphane ULiege

Conference (2017, July 12)

This paper aims at demonstrating how information on the paths of semantic extensions undergone by content words may be incorporated into semantic maps. For this purpose, particular changes that affected ... [more ▼]

This paper aims at demonstrating how information on the paths of semantic extensions undergone by content words may be incorporated into semantic maps. For this purpose, particular changes that affected the meanings of words in the course of the Ancient Greek and of the Ancient Egyptian language history will be investigated. The semantic map model was initially created in order to describe the polysemic patterns of grammatical morphemes (e.g. Haspelmath, 2003). However, recent studies by François (2008), Perrin (2010), Wälchli and Cysouw (2012), and Georgakopoulos et al. (2016) have drawn attention to the lexical domain, showing that the model can be extended to lexical items. It should be noted that the bulk of research has been adopting a synchronic perspective and the limited research that has added the diachronic dimension, has focused mostly on the grammatical domain (e.g. Narrog, 2010). In this paper, we analyze the diachronic evolution of the polysemy network of lexemes in order to produce ‘dynamicised semantic maps’ (Narrog & van der Auwera, 2011) of lexical items. More specifically, we study concepts from the semantic domains of TIME. The data are extracted from dictio-naries, grammars, and the Perseus digital library (http://www.perseus.tufts.edu/hopper/) for Ancient Greek, and from the Thesaurus Linguae Aegyptiae (http://aaew.bbaw.de/tla/), the Ramses corpus (http://ramses.ulg.ac.be), and etymological dictionaries for Ancient Egyptian. Information on synchronic lexical associations are extracted from CLICS (List et al., 2014), an online database containing tendencies of meaning associations. In CLICS, concepts are represented as nodes in the network and instances of polysemy are visualized as links between the nodes. The diachronic dimension of meaning extension may be added to such a network (Figure 1). On the basis of a diachronic analysis of TIME in Ancient Greek (lexical unit: hṓra), which reveals that the meaning ‘time’ is historically prior to the meaning ‘hour,’ we may add a directed arrow representing directionality of change. However, historical priority is not a sufficient criterion for an arrow to be added. Rather, one should be able to show that meaning extensions have a clear motivation.As such, we suggest identifying the cognitive (e.g. metaphor, metonymy, etc.) and the cultural factors that lie behind the observed evolutions. For example, in the case of the Greek concept TIME, one could establish a metonymic motivation between TIME and HOUR, which arises due to the correlation between the canonical time periods and the time these take to unfold. The present study will provide answers to the question of the directionality of change in two particular languages, namely Ancient Greek and Ancient Egyptian. However, our expectation is that by looking at diachrony in this fashion, significant dimensions of directionality of change with cross-linguistic extensions can be revealed. [less ▲]

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See detailInhibiteurs de la pompe à protons et risque d'insuffisance rénale
PAQUOT, Francois ULiege; Krzesinski, Jean-Marie ULiege

in Revue Médicale Suisse (2017)

Regarded as safe and effective for management of upper peptic ulcer disease due to gastric acid secretion, the proton pump inhibitors are among the most commonly prescribed drugs. Their use, however, is ... [more ▼]

Regarded as safe and effective for management of upper peptic ulcer disease due to gastric acid secretion, the proton pump inhibitors are among the most commonly prescribed drugs. Their use, however, is not without concerns. Acute kidney injury, mainly due to acute interstitial nephritis, could happen 1.5 to 2 times more frequently when using these drugs. Moreover, a risk for chronic kidney disease has also be noted with proton pump inhibitor use (1.15 to 1.8 increased risk), although biases may exist due to confounding factors related to the observational nature of the studies. So, caution is required before available results from good prospective randomized studies are available. Renal function should be checked when using these medications and timely cessation should be advised when there is no more clear indication for use. [less ▲]

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See detailRhétorique du détournement vidéoludique. Le cas de Pokémon
Barnabé, Fanny ULiege

Doctoral thesis (2017)

La présente recherche se situe au croisement de plusieurs traditions disciplinaires – les sciences du jeu, les études littéraires, la rhétorique, les cultural studies – et de plusieurs objets – le jeu, le ... [more ▼]

La présente recherche se situe au croisement de plusieurs traditions disciplinaires – les sciences du jeu, les études littéraires, la rhétorique, les cultural studies – et de plusieurs objets – le jeu, le détournement, les fanfictions, machinimas, speedruns, let’s plays et mods. Sans prétendre opérer ici leur synthèse ou leur conciliation, nous tenterons de dégager, entre ces différents domaines, de nouvelles ouvertures : nous montrerons, en circulant parmi eux, qu’ils sont pris dans des tensions, des dynamiques, des questionnements similaires et, surtout, centraux pour la compréhension de la culture populaire contemporaine. Plusieurs objectifs nous animent : définir le détournement et, à travers lui, éclairer sous un autre jour le fonctionnement du jeu ; développer un métadiscours à même de soutenir l’analyse des œuvres produites par les joueurs ; enfin, par la même occasion, défendre l’intérêt d’étudier de près ces œuvres amateurs, trop souvent délaissées par la recherche au profit des pratiques, et qui sont pourtant des épicentres essentiels autour desquels se développent les cultures ludiques. La poursuite de ces objectifs, toutefois, ne va pas sans soulever des questions complexes, qui traversent toute la thèse : quels parallèles et quelle frontière établir entre le détournement et le jeu ? Comment une œuvre est-elle reconnue, étiquetée, classée comme un détournement ? Qu’est-ce au juste qu’une œuvre dans un domaine où l’intertextualité, la reprise, la réinterprétation sont des normes ? Avec quels outils décrire les formes du détournement, et qu’ont en commun les genres disparates regroupés sous cette dénomination ? Nous traiterons ces diverses interrogations en deux temps. La première partie de la thèse, qui comporte deux sous-sections, en constituera le socle théorique : un premier chapitre y aborde les relations intimes entre jeu et détournement, tout en resituant notre recherche dans les différents champs qu’elle fait se croiser ; le second chapitre s’attache à la constitution d’un cadre métadiscursif inspiré de la rhétorique, visant à définir ce que pourraient être des « figures » du détournement vidéoludique. La deuxième partie, plus analytique, servira d’application au cadre précédemment construit, en montrant son utilité sur des études d’œuvres concrètes. Celles-ci sont réparties en trois grandes catégories : les détournements par le play (let’s plays, speedruns, tool-assisted speedruns et machinimas), les détournements du game (fanfictions et mods) et les recontextualisations (« Twitch plays… »). Par ailleurs, en guise de fil conducteur, toutes ces œuvres – de formes et de genres variés – auront pour point commun essentiel d’être dérivées d’un même univers fictionnel : celui de la licence Pokémon. [less ▲]

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See detailGestion intégrée et systémique du risque tempête au sein de la filière forêt-bois
Riguelle, Simon ULiege

Scientific conference (2017, July 11)

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See detailDoes Belgian Holocene speleothem record solar forcing and cold events?
Allan, Mohammed ULiege; Deliège, Adrien ULiege; Nicolay, Samuel ULiege et al

in Climate of the Past Discussions (2017)

We present a decadal-centennial scale Holocene climate record based on trace elements contents from a 65 cm stalagmite (Père Noël) from Belgian Père Noël cave. Père Noël (PN) stalagmite covers the last 12 ... [more ▼]

We present a decadal-centennial scale Holocene climate record based on trace elements contents from a 65 cm stalagmite (Père Noël) from Belgian Père Noël cave. Père Noël (PN) stalagmite covers the last 12.7 ka according to U/Th dating. High spatial resolution measurements of trace elements (Sr, Ba, Mg and Al) were done by Laser-Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS). Trace elements profiles were interpreted as environmental and climate changes in the Han-sur-Lesse region. Power spectrum estimators and continuous wavelet transform were applied on trace elements time series to detect any statistically significant periodicities in the PN stalagmite. Spectral analyses reveal decadal to millennial periodicities (i.e., 68–75, 133–136, 198–209, 291–358, 404–602, 912–1029 and 2365–2670 yr) in the speleothem record. Results were compared to reconstructed sunspot number data to determine whether solar signal is presents in PN speleothem. The occurrence of significant solar periodicities (i.e., cycles of Gleissberg, de Vries, unnamed 500 years, Eddy and Hallstat) supports for an impact of solar forcing on PN speleothem trace elements contents. Moreover, several intervals of significant rapid climate change were detected during the Holocene at 10.3, 9.3–9.5, around 8.2, 6.4–6.2, 4.7–4.5, and around 2.7 ka BP. Those intervals are similar to the cold events evidenced in different natural paleoclimate archivers, suggesting common climate forcing mechanisms related to changes in solar irradiance. [less ▲]

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See detailMesenchymal Stromal Cells Accelerate Epithelial Tight Junction Assembly via the AMP-Activated Protein Kinase Pathway, Independently of Liver Kinase B1
Rowart, Pascal ULiege; ERPICUM, Pauline ULiege; KRZESINSKI, Jean-Marie ULiege et al

in Stem Cells International (2017)

Background. Mesenchymal stromal cells (MSC) are fibroblast-like multipotent cells capable of tissue-repair properties. Given the essentiality of tight junctions (TJ) in epithelial integrity, we ... [more ▼]

Background. Mesenchymal stromal cells (MSC) are fibroblast-like multipotent cells capable of tissue-repair properties. Given the essentiality of tight junctions (TJ) in epithelial integrity, we hypothesized that MSC modulate TJ formation, via the AMP-activated kinase (AMPK) pathway. Liver kinase-β1 (LKB1) and Ca2+-calmodulin-dependent protein kinase kinase (CaMKK) represent the main kinases that activate AMPK. Methods. The in vitro Ca2+ switch from 5 μM to 1.8 mM was performed using epithelial Madin-Darby canine kidney (MDCK) cells cultured alone or cocultured with rat bone marrow-derived MSC or preexposed to MSC-conditioned medium. TJ assembly was measured by assessing ZO-1 relocation to cell-cell contacts. Experiments were conducted using MDCK stably expressing short-hairpin-RNA (shRNA) against LKB1 or luciferase (LUC, as controls). Compound STO-609 (50 μM) was used as CaMKK inhibitor. Results. Following Ca2+ switch, ZO-1 relocation and phosphorylation/activation of AMPK were significantly higher in MDCK/MSC compared to MDCK. No difference in AMPK phosphorylation was observed between LKB1-shRNA and Luc-shRNA MDCK following Ca2+ switch. Conversely, incubation with STO-609 prior to Ca2+ switch prevented AMPK phosphorylation and ZO-1 relocation. MSC-conditioned medium slightly but significantly increased AMPK activation and accelerated TJ-associated distribution of ZO-1 post Ca2+ switch in comparison to regular medium. Conclusions. MSC modulate the assembly of epithelial TJ, via the CaMKK/AMPK pathway independently of LKB1. [less ▲]

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See detailDetermining fine population structure using iterative pruning
Chaichoompu, Kridsadakorn ULiege; Yazew, Fentaw Abegaz; Tongsima, Sissades et al

Poster (2017, July 10)

SNP-based information is used in several existing clustering methods to detect shared genetic ancestry or to identify population substructure (Price et al. 2006, Raj et al. 2016). Here, we present an ... [more ▼]

SNP-based information is used in several existing clustering methods to detect shared genetic ancestry or to identify population substructure (Price et al. 2006, Raj et al. 2016). Here, we present an unsupervised clustering algorithm called the iterative pruning method to capture population structure (IPCAPS). Our method supports ordinal data which can be applied directly to SNP data to identify fine-level population structure and it is built on the iterative pruning Principal Component Analysis (ipPCA) algorithm (Intarapanich et al. 2009). The IPCAPS involves an iterative process using multiple splits based on multivariate Gaussian mixture modeling of principal components and Clustering EM estimation as in Lebret et al. (2015). In each iteration, rough clusters and outliers are also identified using our own method called RubikClust. The fixation index (FST) is known to measure a distance between populations and FST = 0.001 may be said to be genetically distinct among the European populations (Tian et al. 2008, Huckins et al. 2014). To observe fine-level population structure using FST, we examined simulated scenarios of one population, 500-8,000 individuals, 5,000-10,000 independent SNPs in HWE (Balding and Nichols 1995), with 100 replicates for each scenario. The simulated SNPs were encoded as additive coding and there was no missing genotype generated. We introduced negative control by subjecting individuals to be separated into two groups using kmeans. We observed that FST values of divided groups were lower than 0.0008, which can be defined as the minimum FST to detect fine-level population structure. To evaluate the performance of our method, we tested different simulated data sets of 2-3 populations, 250 individuals per population, 10,000 independent SNPs in HWE, and FST=[0.0008,0.005], with 100 replicates for each data set. For real-life data sets, we applied the IPCAPS to Thai (Wangkumhang et al. 2013) and HapMap populations. Our method showed that a population classification accuracy was superior to the ipPCA in simulated scenarios of extremely subtle structure (FST=[0.0009,0.005]). In case of the Thai population, results to detect fine-level structure were obtained as well as in case of the HapMap populations. We are convinced that the IPCAPS has a potential to detect fine-level structure and it will be important in molecular reclassification studies of patients once underlying population structure has been removed. [less ▲]

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See detailIncreased sea ice cover disrupts food web structure in Antarctic coastal benthic ecosystem
Michel, Loïc ULiege; Danis, Bruno; Dubois, Philippe et al

Conference (2017, July 10)

Antarctica currently undergoes strong and contrasted impacts linked to climate change. While the West Antarctic Peninsula is one of the most rapidly warming regions in the world, resulting in sea ice ... [more ▼]

Antarctica currently undergoes strong and contrasted impacts linked to climate change. While the West Antarctic Peninsula is one of the most rapidly warming regions in the world, resulting in sea ice cover decrease, the sea ice cover of East Antarctica unexpectedly tends to increase. Here, we studied shallow (0-20 m) benthic food web structure on the coasts of Petrels Island (Adélie Land, East Antarctica) during an event of unusually high spatial and temporal (two successive austral summers without seasonal break-up) sea ice cover. Using time-tested integrative trophic markers (stable isotope ratios of carbon, nitrogen and sulfur) and state-of-the-art data analysis tools (Bayesian ecological models), we studied the structure of the food web associated to benthic macroinvertebrates communities. In total, 28 taxa spanning most present animal groups (sponges, sea anemones, nemerteans, nematods, sipunculids, sessile and mobile polychaetes, gastropods, bivalves, pycnogonids, crustaceans, sea stars, sea urchins, brittle stars and sea cucumbers) and functional guilds (grazers, deposit feeders, filter feeders, predators, scavengers) were investigated. Our results indicate that the absence of seasonal sea ice breakup deeply influences coastal benthic food webs. We recorded marked differences from literature data, both in terms of horizontal (i.e. primary producers and resources supporting animal populations) and vertical (i.e. trophic level of the studied consumers) structure of the food web. Overall, sympagic algae dominated the diet of many key consumers, and the trophic levels of invertebrates were low, suggesting omnivore consumers relied less on predation and/or scavenging than in normal environmental conditions. Surprisingly, few animals seemed to feed on the extremely abundant benthic biofilm, whose exceptional development was also presumably linked with the peculiar sea ice conditions. Comparison of data obtained in the austral summers of 2013-2014 (first year without seasonal breakup) and 2014-2015 (second year without seasonal breakup) clearly showed that the observed trends were linked to actual temporal changes in invertebrate feeding habits rather than with other potential ecological drivers. Our results provide insights about how Antarctic benthic consumers, which have evolved in an extremely stable environment, might adapt their feeding habits in response to sudden changes in environmental conditions and trophic resource availability. They also show that local and/or global trends of sea ice increase in Antarctica have the potential to cause drastic changes in food web structure and therefore impact benthic communities. This research was funded by the Belgian Federal Science Policy Office (BELSPO) in the framework of the vERSO project (http://www.versoproject.be). [less ▲]

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