Last 7 days
Bookmark and Share    
Full Text
Peer Reviewed
See detailModelling argon dynamics in first-year sea ice
Moreau, S.; Vancoppenolle, M; Zhou, Jiayun ULg et al

in Ocean Modelling (2014), 73

Abstract: Focusing on physical processes, we aim at constraining the dynamics of argon (Ar), a biogeochemically inert gas, within first year sea ice, using observation data and a one-dimensional halo ... [more ▼]

Abstract: Focusing on physical processes, we aim at constraining the dynamics of argon (Ar), a biogeochemically inert gas, within first year sea ice, using observation data and a one-dimensional halo-thermodynamic sea ice model, including parameterization of gas physics. The incorporation and transport of dissolved Ar within sea ice and its rejection via gas-enriched brine drainage to the ocean, are modeled following fluid transport equations through sea ice. Gas bubbles nucleate within sea ice when Ar is above saturation and when the total partial pressure of all three major atmospheric gases (N2, O2 and Ar) is above the brine hydrostatic pressure. The uplift of gas bubbles due to buoyancy is allowed when the brine network is connected with a brine volume above a given threshold. Ice-atmosphere Ar fluxes are formulated as a diffusive process proportional to the differential partial pressure of Ar between brine inclusions and the atmosphere. Two simulations corresponding to two case studies that took place at Point Barrow (Alaska, 2009) and during an ice-tank experiment (INTERICE IV, Hamburg, Germany, 2009) are presented. Basal entrapment and vertical transport due to brine motion enable a qualitatively sound representation of the vertical profile of the total Ar (i.e. the Ar dissolved in brine inclusions and contained in gas bubbles; TAr). Sensitivity analyses suggest that gas bubble nucleation and rise are of most importance to describe gas dynamics within sea ice. Ice-atmosphere Ar fluxes and the associated parameters do not drastically change the simulated TAr. Ar dynamics are dominated by uptake, transport by brine dynamics and bubble nucleation in winter and early spring; and by an intense and rapid release of gas bubbles to the atmosphere in spring. Important physical processes driving gas dynamics in sea ice are identified, pointing to the need for further field and experimental studies. [less ▲]

Detailed reference viewed: 24 (4 ULg)
Full Text
Peer Reviewed
See detailMyocardial cardiotrophin-1 is differentially induced in congenital cardiac defects depending on hypoxemia.
Heying, Ruth; Qing, Ma; SCHUMACHER, Katharina ULg et al

in Future cardiology (2014), 10(1), 53-62

Aim: Cardiotrophin-1 (CT-1) is upregulated by hypoxemia and hemodynamic overload and is characterized by potent hypertrophic and protective properties on cardiac cells. This study aimed to investigate ... [more ▼]

Aim: Cardiotrophin-1 (CT-1) is upregulated by hypoxemia and hemodynamic overload and is characterized by potent hypertrophic and protective properties on cardiac cells. This study aimed to investigate whether CT-1 is differentially induced in the myocardium of infants with congenital cardiac defects depending on hypoxemia. Methods & results: Infants with Tetralogy of Fallot (n = 8) or with large nonrestrictive ventricular septal defect (n = 8) undergoing corrective surgery were investigated. Expression of CT-1 was assessed at mRNA and protein levels in the right atrial and ventricular myocardium. The activation of the STAT-3 and VEGF were measured. Degradation of cardiac troponin-I served as a marker of myocardial damage. CT-1 was detected in all patients with levels negatively correlating to the arterial oxygen saturation. Higher CT-1 expression in Tetralogy of Fallot patients was associated with activation of the JAK/STAT pathway and higher cardiac troponin-I degradation. Conclusion: CT-1 may mediate myocardial hypertrophy and dysfunction in infants with congenital cardiac defects, particularly in those with hypoxemia. [less ▲]

Detailed reference viewed: 8 (1 ULg)
Full Text
See detailRecent results from long-term FTIR monitoring activities at Jungfraujoch: some unexpected trends and new target species
Mahieu, Emmanuel ULg

Scientific conference (2014, January)

Recent results derived from the long-term FTIR monitoring activities conducted by the University of Liège at the Jungfraujoch station are presented, with a focus on new target species.

Detailed reference viewed: 9 (2 ULg)
Full Text
Peer Reviewed
See detailA 660-Kb Deletion with Antagonistic Effects on Fertility and Milk Production Segregates at High Frequency in Nordic Red Cattle: Additional Evidence for the Common Occurrence of Balancing Selection in Livestock
Kumar Kadri, Naveen; Sahana, Goutam; Charlier, Carole ULg et al

in PLoS Genetics (2014), 10(1), 1004049

In dairy cattle, the widespread use of artificial insemination has resulted in increased selection intensity, which has led to spectacular increase in productivity. However, cow fertility has ... [more ▼]

In dairy cattle, the widespread use of artificial insemination has resulted in increased selection intensity, which has led to spectacular increase in productivity. However, cow fertility has concomitantly severely declined. It is generally assumed that this reduction is primarily due to the negative energy balance of high-producing cows at the peak of lactation. We herein describe the fine-mapping of a major fertility QTL in Nordic Red cattle, and identify a 660-kb deletion encompassing four genes as the causative variant. We show that the deletion is a recessive embryonically lethal mutation. This probably results from the loss of RNASEH2B, which is known to cause embryonic death in mice. Despite its dramatic effect on fertility, 13%, 23% and 32% of the animals carry the deletion in Danish, Swedish and Finnish Red Cattle, respectively. To explain this, we searched for favorable effects on other traits and found that the deletion has strong positive effects on milk yield. This study demonstrates that embryonic lethal mutations account for a non-negligible fraction of the decline in fertility of domestic cattle, and that associated positive effects on milk yield may account for part of the negative genetic correlation. Our study adds to the evidence that structural variants contribute to animal phenotypic variation, and that balancing selection might be more common in livestock species than previously appreciated. [less ▲]

Detailed reference viewed: 16 (3 ULg)
Full Text
See detailLettre d'Information N° 12 projet Dacefi
Meunier, Quentin; Mezui Mba, C.; Boldrini, Sylvie et al

E-print/Working paper (2014)

Detailed reference viewed: 11 (0 ULg)
Full Text
Peer Reviewed
See detailWhere are the politics in responsible innovation? European governance, technology assessments, and beyond
Van Oudheusden, Michiel ULg

in Journal of Responsible Innovation (2014), 1(1), 67-86

Responsible innovation (RI) is founded on the idea that present modes of innovating with science and technology fail because they insufficiently take into account societal needs and values. Hence ... [more ▼]

Responsible innovation (RI) is founded on the idea that present modes of innovating with science and technology fail because they insufficiently take into account societal needs and values. Hence, proponents of RI solicit society's opinions in an attempt to render science and technology developments, institutions, and policies more socially responsive. This article asks how the RI concept is taken up and elaborated, based on accounts developed on the EU policy level and on a Flemish, technology assessment level. It finds that, notwithstanding important differences between these two deliberative frameworks, neither one leaves much room for politics, understood as the constitution and contestation of power. Rather, these frameworks largely ignore questions about the politics in and of deliberation, the authoritative allocation of values, and the institutional uptake of deliberative engagements. The article's aim is to provide constructive criticism of the RI paradigm by rendering these political issues explicit and proposing ways of taking them into account. [less ▲]

Detailed reference viewed: 14 (2 ULg)
Full Text
Peer Reviewed
See detailVulvar Skin Disorders throughout Lifetime: About Some Representative Dermatoses
DOYEN, Jean ULg; Demoulin, Stéphanie ULg; DELBECQUE, Katty ULg et al

in BioMed Research International (2014)

Detailed reference viewed: 20 (6 ULg)
Full Text
See detailWelke impact heeft de slachtleeftijd bij vleeskuikens op de zintuiglijke eigenschappen van het vlees?
De Maeseneire, Coraline ULg; Sindic, Marianne ULg; Colot, Catherine et al

Article for general public (2014)

Detailed reference viewed: 7 (0 ULg)
See detailFluxonics
Silhanek, Alejandro ULg

Conference (2014, January)

Detailed reference viewed: 12 (3 ULg)
Full Text
See detail3D City Models and urban information: current issues and perspectives
Billen, Roland ULg; Cutting-Decelle, Anne-Françoise; Marina, Ognen et al

Book published by edpsciences (2014)

Considering sustainable development of cities implies investigating cities in a holistic way taking into account many interrelations between various urban or environmental issues. 3D city models are ... [more ▼]

Considering sustainable development of cities implies investigating cities in a holistic way taking into account many interrelations between various urban or environmental issues. 3D city models are increasingly used in different cities and countries for an intended wide range of applications beyond mere visualization. Could these 3D City models be used to integrate urban and environmental knowledge? How could they be improved to fulfill such role? We believe that enriching the semantics of current 3D city models, would extend their functionality and usability; therefore, they could serve as integration platforms of the knowledge related to urban and environmental issues allowing a huge and significant improvement of city sustainable management and development. But which elements need to be added to 3D city models? What are the most efficient ways to realize such improvement / enrichment? How to evaluate the usability of these improved 3D city models? These were the questions tackled by the COST Action TU0801” Semantic enrichment of 3D city models for sustainable urban development”. This book gathers various materials developed all along the four year of the Action and the significant breakthroughs. [less ▲]

Detailed reference viewed: 86 (12 ULg)
Full Text
Peer Reviewed
See detailIsocinétisme : aspects spécifiques chez le sportif
Croisier, Jean-Louis ULg; Kaux, Jean-François ULg; Crielaard, Jean-Michel ULg et al

in Kinésithérapie Scientifique (2014), 550

Detailed reference viewed: 132 (31 ULg)
Full Text
Peer Reviewed
See detailHollow Cylinder Tests on Boom Clay: Modelling of Strain Localization in the Anisotropic Excavation Damaged Zone
François, B; Labiouse, V; Dizier, A et al

in Rock Mechanic and Rock Engineering (2014), 47(1), 71-86

Detailed reference viewed: 23 (6 ULg)
Full Text
Peer Reviewed
See detailAntiplasmodial anthraquinones and hemisynthetic derivatives from the leaves of Tectona grandis (Verbenaceae)
Kopa, T.K.; Tchinda Tiabou, Alembert ULg; Tala, M.F. et al

in Phytochemistry Letters (2014)

Chemical investigation of the methanol extract of the leaves of Tectona grandis led to the isolation of one new anthraquinone derivative, grandiquinone A (3-acetoxy-8-hydroxy-2-methylanthraquinone) (1 ... [more ▼]

Chemical investigation of the methanol extract of the leaves of Tectona grandis led to the isolation of one new anthraquinone derivative, grandiquinone A (3-acetoxy-8-hydroxy-2-methylanthraquinone) (1), along with nine known compounds: 5,8-dihydroxy-2-methylanthraquinone (2), hydroxysesamone (3), 3-hydroxy-2-methylanthraquinone (4), quinizarine (5), betulinic acid (6), ursolic acid (7), tectograndone (8), corosolic acid (9) and sitosterol 3-O-β-d-glucopyranoside (10). Compounds 2 and 3 were isolated for the first time from the leaves of this plant, while 5 has never been reported from the genus Tectona. Hydroxysesamone (3) and tectograndone (8) were subjected to cyclisation and acetylation reactions to afford two hemisynthetic derivatives, 6,9-dihydroxy-2,2-(dimethyldihydropyrano)-3,4-dihydro-2H-benzo[g]chromene-5,10-dione (11) and acetyltectograndone (12) respectively, which are reported here for the first time. The ethyl acetate-soluble portion, some of the isolated compounds and hemisynthetic derivatives were evaluated for their antiplasmodial activity against the multidrug-resistant Dd2 strain of Plasmodium falciparum. Compound 3 showed a prominent activity, while 2, 8, 9, 11 and 12 showed significant in vitro anti-malarial activity. Compound 1 was weakly active in this test. The structures of the compounds were elucidated by spectroscopic methods and comparison of the data with the literature. [less ▲]

Detailed reference viewed: 17 (0 ULg)
Full Text
Peer Reviewed
See detailGlobal power grids for harnessing world renewable energy
Chatzivasileiadis, Spyros; Ernst, Damien ULg; Andersson, Göran

E-print/Working paper (2014)

The Global Grid advocates the connection of all regional power systems into one electricity transmission system spanning the whole globe. Power systems are currently forming larger and larger ... [more ▼]

The Global Grid advocates the connection of all regional power systems into one electricity transmission system spanning the whole globe. Power systems are currently forming larger and larger interconnections. Environmental awareness and increased electricity consumption leads more investments towards renewable energy sources, abundant in remote locations (off-shore or in deserts). The Global Grid will facilitate the transmission of this “green” electricity to load centers, serving as backbone. This chapter elaborates on the concept presenting four stages that could gradually lead to the development of a globally interconnected power network. Quantitative analyses are carried out for all stages, demonstrating that a Global Grid is both technically feasible and economically competitive. Real price data from Europe and the USA are used to identify the potential of intercontinental electricity trade, showing that substantial profits can be generated through such interconnections. [less ▲]

Detailed reference viewed: 18 (3 ULg)
Full Text
Peer Reviewed
See detailA More Than 20% Increase in Deceased-Donor Organ Procurement and Transplantation Activity After the Use of Donation After Circulatory Death.
Le Dinh, H.; MONARD, Josée ULg; DELBOUILLE, Marie-Hélène ULg et al

in Transplantation proceedings (2014), 46(1), 9-13

BACKGROUND: Organ procurement and transplant activity from controlled donation after circulatory death (DCD) was evaluated over an 11-year period to determine whether this program influenced the ... [more ▼]

BACKGROUND: Organ procurement and transplant activity from controlled donation after circulatory death (DCD) was evaluated over an 11-year period to determine whether this program influenced the transplant and donation after brain death (DBD) activities. MATERIAL AND METHODS: Deceased donor (DD) procurement and transplant data were prospectively collected in a local database for retrospective review. RESULTS: There was an increasing trend in the potential and actual DCD numbers over time. DCD accounted for 21.9% of the DD pool over 11 years, representing 23.7% and 24.2% of the DD kidney and liver pool, respectively. The DBD retrieval and transplant activity increased during the same time period. Mean conversion rate turning potential into effective DCD donors was 47.3%. Mean DCD donor age was 54.6 years (range, 3-83). Donors >/=60 years old made up 44.1% of the DCD pool. Among referred donors, reasons for nondonation were medical contraindications (33.7%) and family refusals (19%). Mean organ yield per DCD donor was 2.3 organs. Mean total procurement warm ischemia time was 19.5 minutes (range, 6-39). In 2012, 17 DCD and 37 DBD procurements were performed in the Liege region, which has slightly >1 million inhabitants. CONCLUSIONS: This DCD program implementation enlarged the DD pool and did not compromise the development of DBD programs. The potential DCD pool might be underused and seems to be a valuable organ donor source. [less ▲]

Detailed reference viewed: 25 (9 ULg)
Full Text
See detailLa qualité d'accueil fait débat
Pirard, Florence ULg

in Revue [Petite] Enfance (2014), 113

La qualité des services d'accueil et d'éducation des jeunes enfants constitue un enjeu sociétal d'actualité, mais peut faire l'objet d'interprétations multiples. Fondé sur les résultats d'une recherche ... [more ▼]

La qualité des services d'accueil et d'éducation des jeunes enfants constitue un enjeu sociétal d'actualité, mais peut faire l'objet d'interprétations multiples. Fondé sur les résultats d'une recherche menée dans une démarche de théorisation ancrée, cet article donne de manière synthétique une grille de lecture de différentes manières de considérer la qualité des services d'accueil et d'éducation des jeunes enfants dans un cadre professionnel. [less ▲]

Detailed reference viewed: 11 (1 ULg)
See detailTechnologie de production de masse d’insectes - INSECTECH
Richard, Gaetan ULg; Hance, Thierry; Fauconnier, Marie-Laure ULg et al

Report (2014)

Detailed reference viewed: 3 (0 ULg)
Full Text
See detailLes instruments anciens - volvelles
Nazé, Yaël ULg

Article for general public (2014)

Detailed reference viewed: 4 (0 ULg)