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See detail“Don't pretend to be my friend!” When an informal brand communication style backfires on social media
Gretry, Anaïs ULg; Horváth, Csilla; Belei, Nina et al

in Journal of Business Research (2017), 74

Social media are now essential platforms for marketing communications, and the volume of consumer-brand in- teractions on these platforms is exploding. Even so, it remains unclear how brands should ... [more ▼]

Social media are now essential platforms for marketing communications, and the volume of consumer-brand in- teractions on these platforms is exploding. Even so, it remains unclear how brands should communicate with consumers to foster relationships and, in particular, to gain their trust. A fundamental decision in this regard is the choice of a communication style, specifically, whether an informal or a formal style should be used in social media communications. In this paper, we investigate how adopting an informal (vs. formal) communication style affects brand trust and demonstrate that using an informal style can either have a positive or negative effect on brand trust, depending on whether consumers are familiar with the brand or not. We further show that these ef- fects occur because consumers expect brands to behave according to social norms, such that the use of an infor- mal style is perceived to be appropriate for familiar brands and inappropriate for unfamiliar ones. [less ▲]

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See detailZinc, manganese and iron interaction within the frd3 Arabidopsis mutant
Scheepers, Maxime ULg; Spielmann, Julien ULg; Goormaghtigh, Erik et al

Poster (2017, February 01)

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See detailUsing unsupervised clustering method and SNP-based information to identify fine-level population structure
Chaichoompu, Kridsadakorn ULg; Yazew, Fentaw Abegaz; Tongsima, Sissades et al

Poster (2017, February 01)

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See detailImproved Blood Glucose Forecasting Models using Changes in Insulin Sensitivity in Intensive Care Patients
Uyttendaele, Vincent ULg; Dickson, Jennifer; Shaw, Geoff et al

Poster (2017, February 01)

Introduction: Hyperglycaemia, hypoglycaemia and glycaemic variability are associated with worsened outcomes and increased mortality in intensive care units. Glycaemic control (GC) using insulin therapy ... [more ▼]

Introduction: Hyperglycaemia, hypoglycaemia and glycaemic variability are associated with worsened outcomes and increased mortality in intensive care units. Glycaemic control (GC) using insulin therapy has shown improved outcomes, but have been proven difficult to repeat or achieve safely. STAR (Stochastic TARgeted) is a model-based glycaemic control protocol using a stochastic model to forecast distributions of likely future changes in insulin sensitivity (SI) based on its current value. This can be used to determine likely future blood glucose (BG) levels for a given intervention, enabling the most optimal dose selection that best overlaps a clinically defined BG target band. This study presents a novel 3D model capable to predict likely future distribution of SI using both current SI and its prior variability (%ΔSI). Methods: Metabolic data from 3 clinical ICU cohorts totalling 819 episodes and 68629 hours of treatment under STAR and SPRINT protocols are used in this study. Data triplets (%ΔSIn, SIn, SIn+1) are created and binned together in a range of %ΔSI = [-100%, 200%] and SIn = [1.0e-7, 2.1e-3] in bin sizes of %ΔSI = 10% and SIn = 0.5e-4. The 5th, 50th, and 95th percentile of SIn+1 are determined for each bin where data density is high enough (>100 triplets) and compared to the previous stochastic model. The predictive power of the two models are compared by computing median [IQR] per-patient percentage prediction of SI within the 5th-95th and 25th-75th percentile ranges of model predictions. Results: Results show the previous model is over-conservative for ~77% of the data, mainly where %ΔSI is within an absolute 25% change. The percentage change in the 90% CI width in this region is reduced by ~25-40%. Conversely, non-conservative regions are also identified, with 90% CI width increased up to ~80%. Predictive power is similar for both model (60.3% [47.8%, 71.5%] vs. 51.2 [42.9%, 59.2%] within 25th-75th and 93.6% [85.7%, 97.3%] vs. 90.7% [84.4%, 94.6%] within 5th-95th range). Conclusions: The new 3D model achieved similar predictive power as the previous model by reducing the 5th-95th percentile prediction range for 77% of the data, predominantly where SI is stable. If the conservatism of the previous model reduces risk of hypoglycaemia, it also inhibits the controller’s ability to reduce BG to the normal range by safely using more aggressive dosing. The 3D new model thus better characterises patient-specific response to insulin, and allows more optimal dosing, increasing performance and safety. [less ▲]

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See detailMicroalgues: du laboratoire au pilote industriel pour la production de molécules bioactives
Franck, Fabrice ULg; Gerards, Thomas ULg

Scientific conference (2017, February 01)

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See detailStrong XUV irradiation of the Earth-sized exoplanets orbiting the ultracool dwarf TRAPPIST-1
Wheatley, Peter J.; Louden, Tom; Bourrier, Vincent et al

in Monthly Notices of the Royal Astronomical Society (2017), 465

We present an XMM-Newton X-ray observation of TRAPPIST-1, which is an ultracool dwarf star recently discovered to host three transiting and temperate Earth-sized planets. We find the star is a relatively ... [more ▼]

We present an XMM-Newton X-ray observation of TRAPPIST-1, which is an ultracool dwarf star recently discovered to host three transiting and temperate Earth-sized planets. We find the star is a relatively strong and variable coronal X-ray source with an X-ray luminosity similar to that of the quiet Sun, despite its much lower bolometric luminosity. We find L_x/L_bol=2-4x10^-4, with the total XUV emission in the range L_xuv/L_bol=6-9x10^-4. Using a simple energy-limited model we show that the relatively close-in Earth-sized planets, which span the classical habitable zone of the star, are subject to sufficient X-ray and EUV irradiation to significantly alter their primary and perhaps secondary atmospheres. Understanding whether this high-energy irradiation makes the planets more or less habitable is a complex question, but our measured fluxes will be an important input to the necessary models of atmospheric evolution. [less ▲]

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See detailXMM-Newton : en route vers une autre décennie de découvertes
Rauw, Grégor ULg

Article for general public (2017)

Au mois de décembre 2016, cela faisait 17 ans que XMM-Newton fut lancé par une fusée Ariane V. Equipé de ses trois modules miroirs comportant chacun 58 miroirs imbriqués les uns dans les autres, XMM ... [more ▼]

Au mois de décembre 2016, cela faisait 17 ans que XMM-Newton fut lancé par une fusée Ariane V. Equipé de ses trois modules miroirs comportant chacun 58 miroirs imbriqués les uns dans les autres, XMM-Newton est à l’affût de l’émission X de sources cosmiques de tout genre. Malgré sa longévité, XMM-Newton reste à ce jour un des observatoires les plus sollicités au monde. Chaque année, les astrophysiciens proposent des programmes d’observation qui totalisent à peu près 6 fois le temps d’observation disponible! La compétition pour les observations avec XMM est donc très rude. Et a priori cela pourrait continuer encore comme cela pendant quelques années. De fait, les réserves de carburant et la performance des panneaux solaires indiquent que la mission pourrait encore fonctionner au moins 10 ans si les budgets le permettent1! [less ▲]

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See detailGlomerular filtration rate in healthy living potential kidney donors: a meta-analysis supporting the construction of the the Full Age Spectrum equation.
Pottel, H; Hoste, L; Yayo, E et al

in Nephron (2017), 135(2), 105-119

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See detailAttack-Prevention and Damage-Control Investments in Cybersecurity
Lam, Wing Man Wynne ULg

Scientific conference (2017, February)

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See detailLa réforme de l'aide juridique : suivez le guide !
Michiels, Olivier ULg; Falque, Géraldine ULg

in Les droits du justiciable face à la justice pénale (2017)

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See detailIntention, image et singularité selon le premier Sartre : réflexion sur les propriétés et les fonctions de l'acte d'imagination
Recchia, Fabio ULg

in Bulletin d'Analyse Phénoménologique (2017, February)

Partant d’une problématisation de la méthode phénoménologique mise en jeu par "L’Imaginaire", nous proposons de relire les développements de ce texte à partir de la perspective offerte par la théorie de ... [more ▼]

Partant d’une problématisation de la méthode phénoménologique mise en jeu par "L’Imaginaire", nous proposons de relire les développements de ce texte à partir de la perspective offerte par la théorie de l’intentionnalité du premier Sartre. Nous tenterons ainsi de dégager l’unité systématique du projet sartrien d’une « phénoménologie de l’image » en le rapportant aux propositions philosophiques posées de manière décisive par "l’article sur l’intentionnalité". Par ce biais, il s’agira également de fixer les propriétés de la conscience imageante, ainsi que les fonctions jouées par l’acte d’imagination dans l’économie générale de la conscience, en particulier dans l’événement de sa personnalisation. De sorte que nous parcourons les tensions reliant l’imagination de la conscience à son ipséité ; tandis que, du point de vue de l’histoire de la philosophie, nous examinerons certaines des torsions qu’appliqua Sartre sur l’analyse husserlienne de l’image afin d’approfondir celle-ci dans la direction d’une philosophie de la liberté personnelle du sujet. [less ▲]

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See detailClinical settings in knee osteoarthritis: Pathophysiology guides treatment
Herrero-Beaumont, Gabriel; Roman-Blas, Jorge A; Bruyère, Olivier ULg et al

in Maturitas (2017), 96

Osteoarthritis (OA) is the most common chronic joint disorder and its prevalence increases rapidly during midlife. Complex interactions of genetic alterations, sex hormone deficit, and aging with ... [more ▼]

Osteoarthritis (OA) is the most common chronic joint disorder and its prevalence increases rapidly during midlife. Complex interactions of genetic alterations, sex hormone deficit, and aging with mechanical factors and systemic inflammation-associated metabolic syndrome lead to joint damage. Thus, the expression of a clinical phenotype in the early stages of OA relies on the main underlying pathway and predominant joint tissue involved at a given time. Moreover, OA often coexists with other morbidities in the same patient, which in turn condition the OA process. In this scenario, an appropriate identification of clinical phenotypes, especially in the early stages of the disease, may optimize the design of individualized treatments in OA. An ESCEO-EUGMS (European Union Geriatric Medicine Society) working group has recently suggested possible patient profiles in OA. Hereby, we propose the existence of 4 clinical phenotypes – biomechanical, osteoporotic, metabolic and inflammatory – whose characterization would help to properly stratify patients with OA in clinical trials or studies. Further research in this field is warranted. [less ▲]

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See detailQuantitative determination of salbutamol sulfate impurities using achiral supercritical fluid chromatography
Dispas, Amandine ULg; Desfontaine, Vincent; Andri, Bertyl ULg et al

in Journal of Pharmaceutical & Biomedical Analysis (2017), 134

In the last years, supercritical fluid chromatography has largely been acknowledged as a singular and performing technique in the field of separation sciences. Recent studies highlighted the interest of ... [more ▼]

In the last years, supercritical fluid chromatography has largely been acknowledged as a singular and performing technique in the field of separation sciences. Recent studies highlighted the interest of SFC for the quality control of pharmaceuticals, especially in the case of the determination of the active pharmaceutical ingredient (API).Nevertheless, quality control requires also the determination of impurities. The objectives of the present work were to i) demonstrate the interest of SFC as a reference technique for the determination of impurities in salbutamol sulfate API and ii) to propose an alternative to a reference HPLC method from the European Pharmacopeia (EP) involving ionpairing reagent. Firstly, a screening was carried out to select the most adequate and selective stationary phase. Secondly, in the context of robust optimization strategy, the method was developed using design space methodology. The separation of salbutamol sulfate and related impurities was achieved in 7 minutes, which is seven times faster than the LC-UV method proposed by European Pharmacopeia (total run time of 50 minutes). Finally, full validation using accuracy profile approach was successfully achieved for the determination of impurities B, D, F and G in salbutamol sulfate raw material. The validated dosing range covered 50 to 150 % of the targeted concentration (corresponding to 0.3 % concentration level), LODs close to 0.5 μg/mL were estimated. The SFC method proposed in this study could be presented as a suitable fast alternative to EP LC method for the quantitative determination of salbutamol impurities. [less ▲]

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See detailLes acteurs: introduction
Dubois, Christophe ULg

in Hendrick, Aude; Musin, Aude; Rousseaux, Xavier (Eds.) et al Les mots de la justice (2017)

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