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See detailIs oral feeding compatible with an unresponsive wakefulness syndrome?
MELOTTE, Evelyne ULiege

Poster (2017, November)

Introduction : Vegetative state/unresponsive wakefulness syndrome (VS/UWS) is defined by the presence of eye-opening and the absence of awareness and voluntary movement [1]. VS/UWS patients classically ... [more ▼]

Introduction : Vegetative state/unresponsive wakefulness syndrome (VS/UWS) is defined by the presence of eye-opening and the absence of awareness and voluntary movement [1]. VS/UWS patients classically receive hydration and nutrition through an enteral feeding tube. Objective - Methods : We retrospectively reviewed the clinical information of 65 VS/UWS patients (aged 45±12; range 16-85 years) evaluated at the CHU hospital of liege searching for mention of oral feeding. VS/UWS diagnosis was made after repeated behavioral assessments using the standardized coma recovery scale–revised (CRS-R, [2]) in association with complementary evaluations using neuroimaging techniques. Results : Of the 65 VS/UWS patients, two could resume oral feeding (3%). One could achieve full oral feeding and the other had oral feeding in addition to gastrostomy feeding. Neuroimaging evaluations showed in both patients a massive decrease in the spontaneous brain activity and its functional connectivity (using functional magnetic resonance imaging), bilateral cerebral cortex hypometabolism and preserved metabolism in the brainstem and cerebellum (using positron emission tomography). Discussion – Conclusion – Clinical message : oral feeding is rare in VS/UWS patients (3% in our cohort). Based on neuroimaging results, this behaviour does not seem to be incompatible with the diagnosis of VS/UWS but the neuromecanistic root, which allows this behavior, still needs to be elucidate. This study also emphasizes the importance of assess and manage deglutition in patients with altered state of consciousness regardless of their level of consciousness. Tactile oro-facial stimulation, manual therapy, taste stimulation and therapeutic feeding can be another “gateway” to interact with these patients and improve their quality of life. [less ▲]

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See detailOn the Edge of Comics Criticism
Crucifix, Benoît ULiege

in CLOSURE. Kieler e-Journal für Comicforschung (2017), 4

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See detailFrom combinatorial games to shape-symmetric morphisms
Rigo, Michel ULiege

Scientific conference (2017, November)

The general aim of these lectures is to present some interplay between combinatorial game theory (CGT) and combinatorics on (multidimensional) words. In the first introductory lecture, we present some ... [more ▼]

The general aim of these lectures is to present some interplay between combinatorial game theory (CGT) and combinatorics on (multidimensional) words. In the first introductory lecture, we present some basic concepts from combinatorial game theory (positions of a game, Nim-sum, Sprague-Grundy function, Wythoff's game, ...). We also review some concepts from combinatorics on words. We thus introduce the well-known k-automatic sequences and review some of their characterizations (in terms of morphisms, finiteness of their k-kernel,...). These sequences take values in a finite set but the Sprague-Grundy function of a game, such as Nim of Wythoff, is usually unbounded. This provides a motivation to introduce k-regular sequences (in the sense of Allouche and Shallit) whose k-kernel is not finite, but finitely generated. In the second lecture, games played on several piles of token naturally give rise to a multidimensional setting. Thus, we reconsider k-automatic and k-regular sequences in this extended framework. In particular, determining the structure of the bidimensional array encoding the (loosing) P-positions of the Wythoff's game is a long-standing and challenging problem in CGT. Wythoff's game is linked to non-standard numeration system: P-positions can be determined by writing those in the Fibonacci system. Next, we present the concept of shape-symmetric morphism: instead of iterating a morphism where images of letters are (hyper-)cubes of a fixed length k, one can generalize the procedure to images of various parallelepipedic shape. The shape-symmetry condition introduced twenty years ago by Maes permits to have well-defined fixed point. In the last lecture, we move to generalized numeration systems: abstract numeration systems (built on a regular language) and link them to morphic (multidimensional) words. In particular, pictures obtained by shape-symmetric morphisms coincide with automatic sequences associated with an abstract numeration system. We conclude these lectures with some work in progress about games with a finite rule-set. This permits us to discuss a bit Presburger definable sets. [less ▲]

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See detailStand-level wind damage can be assessed using diachronic photogrammetric canopy height models
Renaud, Jean-Pierre; Vega, Cédric; Durrieu, Sylvie et al

in Annals of Forest Science : a Multidisciplinary and International Journal (2017)

-Key message Diachronic photogrammetric canopy height models can be used to quantify at a fine scale changes in dominant height and wood volume following storms. The regular renewal of aerial surveys ... [more ▼]

-Key message Diachronic photogrammetric canopy height models can be used to quantify at a fine scale changes in dominant height and wood volume following storms. The regular renewal of aerial surveys makes this approach appealing for monitoring forest changes. -Context The increasing availability of aerial photographs and the development of dense matching algorithms open up new possibilities to assess the effects of storm events on forest canopies. -Aims The objective of this research is to assess the potential of diachronic canopy height models derived from photogrammetric point clouds (PCHM) to quantify changes in dominant height and wood volume of a broadleaved forest following a major storm. -Methods PCHMs derived from aerial photographs acquired before and after a storm event were calibrated using 25 field plots to estimate dominant height and volume using various modeling approaches. The calibrated models were combined with a reference damage maps to estimate both the withinstand damage variability, and the amount of volume impacted. -Results Dominant height was predicted with a root mean squared error (RMSE) of 4%, and volume with RMSEs ranging from 24 to 32% according to the type of model. The volume impacted by storm was in the range of 42–76%. Overall, the maps of dominant height changes provided more details about within-stand damage variability than conventional photointerpretation do. -Conclusion The study suggests a promising potential for exploiting PCHM in pursuit of a rapid localization and quantification of wind-throw damages, given an adapted sampling design to calibrate models. [less ▲]

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See detailDu texte à la pratique : pour une sémiotique expérimentale
Dondero, Maria Giulia ULiege

in Semiotica (2017), 219

Our essay aims at continuing the work of Jacques Fontanille, who developed a Semiotics of Practice next to a Semiotics of Text. This work, and especially Pratiques sémiotiques (2008), takes up a problem ... [more ▼]

Our essay aims at continuing the work of Jacques Fontanille, who developed a Semiotics of Practice next to a Semiotics of Text. This work, and especially Pratiques sémiotiques (2008), takes up a problem already formulated by Jean-Marie Floch in the article « Êtes-vous arpenteurs ou somnambules ? L’élaboration d’une typologie comportementale des voyageurs du métro » (1990). We will initially retrace the debate about the epistemological relationship between text and practice, outlining the forms of enunciative praxis. Secondly, we propose the concept of we will consider the visualization that we call ‘notation’: this analytical form of mediation between text and practice does not have the same status of in-vivo textualisations, but it works like an ex-post reconstruction which highlights the main gestures and exchanges while performing their grammaticalization. A more general aim of this essay is an enquiry into the legitimate objects of textual semiotics: what are the objects that it can analyze without betraying its principle of immanence, but also without being unable to analyze practice [less ▲]

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See detailInappropriate claims from non-equivalent medications in osteoarthritis: a position paper endorsed by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO)
Bruyère, Olivier ULiege; Cooper, Cyrus ULiege; Al-Daghri, Nasser ULiege et al

in Aging Clinical and Experimental Research (2017), (Online first),

Osteoarthritis (OA) is a progressive joint disease, that occurs frequently in the aging population and is a major cause of disability worldwide. Both glucosamine and chondroitin are biologically active ... [more ▼]

Osteoarthritis (OA) is a progressive joint disease, that occurs frequently in the aging population and is a major cause of disability worldwide. Both glucosamine and chondroitin are biologically active molecules that are substrates for proteoglycan, an essential component of the cartilage matrix. Evidence supports the use of glucosamine and chondroitin as symptomatic slow-acting drugs for osteoarthritis (SYSADOAs) with impact on OA symptoms and disease-modifying effects in the long term. Glucosamine and chondroitin are administered in exogenous form as a sulfate salt and multiple formulations of these agents are available, both as prescription-grade products and nutritional supplements. However, while all preparations may claim to deliver a therapeutic level of glucosamine or chondroitin not all are supported by clinical evidence. Only patented crystalline glucosamine sulfate (pCGS) is shown to deliver consistently high glucosamine bioavailability and plasma concentration in humans, which corresponds to demonstrated clinical efficacy. Similarly, clinical evidence supports only the pharmaceutical-grade chondroitin sulfate. The European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) advocates, through careful consideration of the evidence base, that judicious choice of glucosamine and chondroitin formulation is essential to maximize clinical benefit, patient adherence and satisfaction with treatment. In future, the ESCEO recommends that complex molecules with biological activity such as pCGS may be treated as “biosimilars” akin to the European Medicines Agency guidance on biological medicinal products. It seems likely that for all other complex molecules classed as SYSADOAs, the recommendation to use only formulations clearly supported by the evidence-base should apply. [less ▲]

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See detailCoordinated Supervisory Control of Multi-Terminal HVDC Grids: a Model Predictive Control Approach
Papangelis, Lampros ULiege; Debry, Marie-Sophie; Panciatici, Patrick et al

in IEEE Transactions on Power Systems (2017), 32(6), 4673-4683

A coordinated supervisory control scheme for future multi-terminal High-Voltage Direct-Current (HVDC) grids is proposed. The purpose is to supervise the grid and take appropriate actions to ensure power ... [more ▼]

A coordinated supervisory control scheme for future multi-terminal High-Voltage Direct-Current (HVDC) grids is proposed. The purpose is to supervise the grid and take appropriate actions to ensure power balance and prevent or remove voltage or current limit violations. First, using DC current and voltage measurements, the power references of the various Voltage Sources Converters (VSC) are updated according to participation factors. Next, the setpoints of the converters are smoothly adjusted to track those power references, while avoiding or correcting limit violations. The latter function resorts to Model Predictive Control and a sensitivity model of the system. The efficiency of the proposed scheme has been tested through dynamic simulations of a five-terminal HVDC grid interconnecting two asynchronous AC areas and a wind farm. [less ▲]

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See detailLe codex descriptus arthurien
Winand, Véronique ULiege

Scientific conference (2017, October 31)

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See detailCarbon and nutrients sources and transformation in the River Sabaki, Kenya
Tamooh, FT; Shawlet, C; Borges, Alberto ULiege et al

Poster (2017, October 30)

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See detailImproving CFD prediction of drag on Paralympic tandem athletes: influence of grid resolution and turbulence model
Mannion, Paul; Toparlar, Yasin; Blocken, Bert et al

in Sports Engineering (2017)

Tandem cycling enables visually impaired athletes to compete in cycling in the Paralympics. Tandem aerodynamics can be analysed by track measurements, wind-tunnel experiments and numerical simulations ... [more ▼]

Tandem cycling enables visually impaired athletes to compete in cycling in the Paralympics. Tandem aerodynamics can be analysed by track measurements, wind-tunnel experiments and numerical simulations with computational fluid dynamics (CFD). However, the proximity of the pilot (front) and the stoker (rear) and the associated strong aerodynamic interactions between both athletes present substantial challenges for CFD simulations, the results of which can be very sensitive to computational parameters such as grid topology and turbulence model. To the best of our knowledge, this paper presents the first CFD and wind-tunnel investigation on tandem cycling aerodynamics. The study analyses the influence of the CFD grid topology and the turbulence model on the aerodynamic forces on pilot and stoker and compares the results with wind-tunnel measurements. It is shown that certain combinations of grid topology and turbulence model give trends that are opposite to those shown by other combinations. Indeed, some combinations provide counterintuitive drag outcomes with the stoker experiencing a drag force up to 28% greater than the pilot. Furthermore, the application of a blockage correction for two athlete bodies in close proximity is investigated. Based on a large number of CFD simulations and validation with wind-tunnel measurements, this paper provides guidelines for the accurate CFD simulation of tandem aerodynamics. [less ▲]

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See detailAgeism: a lifelong blemish ?
Flamion, Allison ULiege

Scientific conference (2017, October 30)

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See detailDemonstrating GPIbα-thrombin interaction in procoagulant platelet formation leads to identification of potential specific inhibitors.
Bourcy, Morgane ULiege; Pasalic, Leonardo; Wang, Samuel et al

Conference (2017, October 30)

Procoagulant platelets are a highly activated platelets-subpopulation which support thrombin generation. We previously reported that coronary artery disease (CAD) patients have excess procoagulant ... [more ▼]

Procoagulant platelets are a highly activated platelets-subpopulation which support thrombin generation. We previously reported that coronary artery disease (CAD) patients have excess procoagulant platelet response to thrombin. Thrombin directly activates platelets via cleavage of PAR1 and PAR4, but is also known to interact with GPIbα via exosite II. Aim: To understand the mechanism of thrombin induced procoagulant platelets and to generate novel antiplatelet therapies. Hypothesis: Involvement of both PAR-dependent and GPIbα-thrombin interaction pathways. Methods: Procoagulant platelets detected by FACS (GSAO, P-selectin, lactadherin) in whole blood and washed platelets after treatment with PAR, GPIbα, exosite II inhibitors and heparins prior to thrombin stimulation. Results: Preincubation with combined PAR1 and PAR4 inhibitors reduced procoagulant platelet formation by 40±5.7%, indicating PAR pathways are not sufficient for thrombin effect. Thrombin exosite II was implicated by reduction of thrombin induced procoagulant platelets by exosite II targeting aptamer (92±4.1%) and heparin. Interaction with GPIbα was demonstrated using competition studies with recombinant soluble GPIbα, glycocalicin (49±7.7%). Involvement of the N-terminus of GPIbα was implied by use of NK protease which cleaves GPIbα proximal to the thrombin binding site (39.5±2.9%). Additive inhibition of procoagulant platelet formation after thrombin stimulation was achieved by combination of GPIbα cleavage and PAR1 and PAR4 inhibition. Having demonstrated a role for displacement of thrombin from GPIbα in targeting procoagulant platelet formation, we evaluated the effect of potential inhibitors of this binding on procoagulant platelet formation in healthy controls and CAD patients and one (inhibitor X) resulted in selective targeting of procoagulant platelets (40.5±10% and 40.6±9.5% respectively). Conclusion: The GPIbα/thrombin exosite II interaction is strongly implicated in thrombin induced procoagulant platelet formation. We identify a potential therapeutic that specifically targets procoagulant platelets as a possible adjunct anti-platelet therapy in CAD. We aim to confirm our results ex vivo and in vivo by using PAR4 knockout and GPIb mutated mice. [less ▲]

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See detailLa traduction collaborative: Entretien avec Holger Fock et Sabine Müller, en présence de Mathias Enard
Neelsen, Sarah ULiege

Speech/Talk (2017)

Sabine Müller et Holger Fock, traducteurs allemands spécialisés dans la traduction de littérature française contemporaine et lauréats du prestigieux prix de traduction Eugen Helmlé, ont traduit plusieurs ... [more ▼]

Sabine Müller et Holger Fock, traducteurs allemands spécialisés dans la traduction de littérature française contemporaine et lauréats du prestigieux prix de traduction Eugen Helmlé, ont traduit plusieurs romans de Mathias Énard, notamment Boussole (all. Kompass), récompensé en France par le Prix Goncourt. Ils présentent dans un entretien croisé avec Mathias Enard, professeur en résidence à l'ULiège, ce travail extrêmement exigeant, récompensé par le Prix littéraire de Leipzig pour la compréhension européenne, en mettant l'accent sur la question de la traduction collaborative, les relations avec l'auteur et la maison d'édition, ainsi que la recherche documentaire. [less ▲]

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See detailAtelier de lecture - Freinet et la pédagogie 1.
Glorie, Caroline ULiege

Conference (2017, October 27)

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See detailLes fictions d'anticipation
Stienon, Valérie ULiege

Conference given outside the academic context (2017)

Si la science-fiction est repérable comme genre littéraire et secteur éditorial en France à partir des années 1950, il n’en va pas de même pour la littérature d’anticipation publiée avant cette date ... [more ▼]

Si la science-fiction est repérable comme genre littéraire et secteur éditorial en France à partir des années 1950, il n’en va pas de même pour la littérature d’anticipation publiée avant cette date. Hormis la figure emblématique de Jules Verne et le succès des « Voyages extraordinaires », elle semble avoir été complètement oubliée. Elle est pourtant abondante et variée, allant du merveilleux scientifique au récit de vulgarisation en passant par l’utopie narrative. Elle est aussi particulièrement créative, s’exprimant dans des formats, des supports et des registres diversifiés : journal, revue, livre, fascicule pour la jeunesse, bande dessinée, roman graphique, fiction télévisuelle. Elle est enfin révélatrice de l’histoire des idées de l’époque qu’elle accompagne, représentant les rêves de société nouvelle, les craintes de catastrophes, l’avancée des progrès techniques et les aléas des découvertes scientifiques.Quels sont les principaux auteurs, les œuvres notables, les thématiques récurrentes de la fiction d’anticipation qui émerge dans la première moitié du XIXe siècle et s’étend sur un siècle et demi ? L’objectif de la formation est de retracer l’histoire méconnue de cette production généralement considérée de manière problématique comme de la science-fiction « archaïque ». Le panorama historique sera appuyé sur une étude des genres littéraires et médiatiques en les situant dans leurs contextes socioculturels, leurs dispositifs éditoriaux et les ressources de l’image. De nombreux exemples mettront en perspective les œuvres qui ont préparé l’imaginaire futuriste de notre époque. Un volet de la formation sera spécifiquement centré sur les productions contemporaines, envisagées dans leurs expressions littéraires, cinématographiques et vidéoludiques. La réflexion portera notamment sur les cas particuliers de la dystopie, de l’uchronie et du « steampunk ». [less ▲]

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See detailCapabilités et sans-abrisme
De Backer, Renaud ULiege

in Cahiers Lutte Contre les Discriminations (2017), 5

L’expérience de sans-abrisme se caractérise par un non-recours important aux droits sociaux, notamment en matière de soins de santé. Alors que ce phénomène peut être appréhendé (par la population générale ... [more ▼]

L’expérience de sans-abrisme se caractérise par un non-recours important aux droits sociaux, notamment en matière de soins de santé. Alors que ce phénomène peut être appréhendé (par la population générale, par certains professionnels du champ psychomédicosocial) comme résultant de choix libres, force est de constater que les conditions d’existence et l’inadaptation du système de soins à la singularité du public empêche de poser, réellement, ce choix. Ainsi, à l’instar des tensions actuelles que connaît le secteur du sans-abrisme, le non-recours aux soins s’appréhende de façon ambivalente. En renouvelant le regard qui est porté sur ce phénomène, et plus largement sur le sans-abrisme, à travers l’approche par les capabilités, le présent article cherche à dépasser les grilles de lecture ressourcistes et utilitaristes au profit d’une analyse centrée sur la liberté des personnes. [less ▲]

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See detailEmancipation au coeur de l'insertion ?
Orianne, Jean-François ULiege

Conference given outside the academic context (2017)

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See detailCopper-based p-type semiconducting oxides: from materials to devices
Avelas Resende, João ULiege

Doctoral thesis (2017)

Detailed reference viewed: 35 (6 ULiège)