Last 7 days
Bookmark and Share    
Full Text
See detailLa gestion des ressources publiques : acteurs, enjeux et processus
Piron, Damien ULg; Weerts, Audrey ULg; Wintgens, Sophie ULg

in Pyramides : Revue du Laboratoire d'Etudes et de Recherches en Administration Publique (2017), 28

Detailed reference viewed: 27 (4 ULg)
Full Text
See detailGenetic predisposition to breast cancer occuring in a male-to-female transsexual patient
Potorac, Iulia ULg; CORMAN, Vinciane ULg; Manto, Florence ULg et al

in Abstract book : Symposium "Perspectives in Endocrinology" (2017, January)

Detailed reference viewed: 29 (1 ULg)
Full Text
See detailVous êtes formidables
RADERMECKER, Régis ULg

in Revue de l'Association Belge du Diabète (2017), 60

Detailed reference viewed: 14 (0 ULg)
Full Text
Peer Reviewed
See detailLa cigarette électronique : état des connaissances à propos des aspects toxicologiques
DEVILLE, Marine ULg; CHARLIER, Corinne ULg

in Revue Médicale de Liège (2017), 72(1), 20-24

La cigarette électronique, aussi appelée e-cigarette, est présentée comme une alternative au tabagisme qui serait moins nocive pour la santé. Son fonctionnement repose sur la conversion d’un liquide en ... [more ▼]

La cigarette électronique, aussi appelée e-cigarette, est présentée comme une alternative au tabagisme qui serait moins nocive pour la santé. Son fonctionnement repose sur la conversion d’un liquide en vapeur, sous l’action de la chaleur générée par un filament présent dans un atomiseur. Le liquide est majoritairement composé de propylène glycol et/ou de glycérine, utilisé(s) pour produire l’effet de fumée, auxquels s’ajoutent des arômes et, éventuellement, de la nicotine. A l’exception de cette dernière, potentiellement létale lorsqu’elle est ingérée à haute dose, ces constituants sont généralement reconnus comme sans danger. Cependant, les conséquences d’une inhalation chronique de propylène glycol sont méconnues. Avantageusement, les composés qui rendent la cigarette traditionnelle particulièrement nuisible – nitrosamines, formaldéhyde, métaux, monoxyde de carbone,… - sont soit absents, soit présents en faible quantité dans la vapeur d’une e-cigarette, sans comparaison avec les taux mesurés dans la fumée d’une cigarette conventionnelle. Il en résulte un profil de toxicité rassurant pour la e-cigarette, bien que son efficacité dans le sevrage tabagique reste à démontrer. [less ▲]

Detailed reference viewed: 50 (5 ULg)
Full Text
See detailLe concept de duration : une présentation heuristique
Bair, Jacques ULg

Learning material (2017)

La duration est fondamentale en mathématiques financières. Nous la présentons de deux manières complémentaires qui sont qualifiées de classique et d’heuristique. La seconde méthode nous paraît originale et ... [more ▼]

La duration est fondamentale en mathématiques financières. Nous la présentons de deux manières complémentaires qui sont qualifiées de classique et d’heuristique. La seconde méthode nous paraît originale et bien adaptée pour amener les étudiants à effectuer un travail de recherche sur un problème concret et pour appliquer de nombreux concepts classiquement enseignés dans les programmes de mathématiques. [less ▲]

Detailed reference viewed: 11 (1 ULg)
Full Text
Peer Reviewed
See detailInfluence of the balls kinematics of axially loaded ball bearings on Coulombic frictional dissipations
Bozet, Jean-Luc ULg; Servais, Christophe ULg

in Journal of Tribology (2017), 139(1),

Ball bearings have been used for a long time. Nevertheless, the description of their behavior remains incomplete in spite of the large number of surveys dedicated to ball bearings. Particularly, the exact ... [more ▼]

Ball bearings have been used for a long time. Nevertheless, the description of their behavior remains incomplete in spite of the large number of surveys dedicated to ball bearings. Particularly, the exact balls kinematics has still to be addressed in depth. This paper proposes a new way to calculate the balls kinematics by using a simplified quasi-static approach for dry lubricated and axially loaded ball bearings. This method does not use the classical restrictive race control assumptions. More specifically, the role played by the balls kinematics is emphasized by means of the power dissipated within contacts between balls and races. The need for a correct evaluation of the balls behavior is illustrated by using an example, viz. a ball bearing of cryogenic engine turbopump. Indeed, the dissipated power is one of the main concerns in this particular case. [less ▲]

Detailed reference viewed: 41 (13 ULg)
Full Text
Peer Reviewed
See detailHabitat selection and reproduction of newts in networks of fish and fishless aquatic patches
Winandy, Laurane ULg; Legrand, Pauline ULg; Denoël, Mathieu ULg

in Animal Behaviour (2017), 123

The spatial distribution of organisms in patchy environments can be determined by the relationship between habitat quality and animal behaviour. In species with complex life cycles, such as pond-breeding ... [more ▼]

The spatial distribution of organisms in patchy environments can be determined by the relationship between habitat quality and animal behaviour. In species with complex life cycles, such as pond-breeding amphibians, the selection of a suitable wetland is crucial. While the traditional view of amphibian ecology suggests strong site fidelity and low vagility, more recent research highlights mechanisms involving active site choice through avoidance behaviour and bet-hedging strategies in heterogeneous environments. The introduction of fish to the aquatic environment is one of the factors that may alter site selection and lead to local dispersal. In this context, we investigated the habitat choice of Alpine newts, Ichthyosaura alpestris, in networks of fish (Carassius auratus) and fishless aquatic patches. Using a laboratory design consisting of aquaria divided into two water tanks connected by a terrestrial platform, we assessed newt distribution and movement between patches. During the breeding period, we compared the reproductive success of individuals in two types of networks. We found that newts escaped fish by rapidly changing aquatic patches and then aggregating in safe aquatic patches that were free of fish. In the fish network, newts maintained reproduction, but the high local abundance resulted in decreased sexual activity and egg production and increased use of the terrestrial habitat. However, in the fishless network, newts moved between aquatic patches several times, exhibited more courtship behaviour and laid more eggs than they did in the fish networks. Our results showed both adaptive habitat switching due to environmental risks in the fish network and habitat supplementation (i.e. use of alternative resources) in the fishless network. Such studies on movement behaviour and habitat selection have conservation implications in showing that the persistence of native species in invaded networks depends on the rescue effect, with immigration to fish-free habitats potentially preventing local extinction. [less ▲]

Detailed reference viewed: 48 (15 ULg)
Full Text
Peer Reviewed
See detailImpact of the cumulated proteins and energy deficits on ICU patient’s outcome
PAGE, Isaline ULg; Warnier, Stéphanie; NYS, Monique ULg et al

in Annals of Intensive Care (2017, January), 7(Suppl1), 200

Detailed reference viewed: 19 (2 ULg)
Full Text
Peer Reviewed
See detailDynamics and emissions of N2O in groundwater: A review
Jurado Elices, Anna ULg; Borges, Alberto ULg; Brouyère, Serge ULg

in Science of the Total Environment (2017), 584-585C

This work reviews the concentrations, the dynamics and the emissions of nitrous oxide (N2O) in groundwater. N2O is an important greenhouse gas (GHG) and the primary stratospheric ozone depleting substance ... [more ▼]

This work reviews the concentrations, the dynamics and the emissions of nitrous oxide (N2O) in groundwater. N2O is an important greenhouse gas (GHG) and the primary stratospheric ozone depleting substance. The major anthropogenic source that contributes to N2O generation in aquifers is agriculture because the use of fertilizers has led to the widespread groundwater contamination by inorganic nitrogen (N) (mainly nitrate, NO3−). Once in the aquifer, this inorganic N is transported and affected by several geochemical processes that produce and consume N2O. An inventory of dissolved N2O concentrations is presented and the highest dissolved concentration is about 18.000 times higher than air-equilibrated water (up to 4004 μg N L-1). The accumulation of N2O in groundwater is mainly due to denitrification and to lesser extent to nitrification. Their occurrence depend on the geochemical (e.g., NO3−, dissolved oxygen, ammonium and dissolved organic carbon) as well as hydrogeological parameters (e.g., groundwater table fluctuations and aquifer permeability). The coupled understanding of both parameters is necessary to gain insight on the dynamics and the emissions of N2O in groundwater. Overall, groundwater indirect N2O emissions seem to be a minor component of N2O emissions to the atmosphere. Further research might be devoted to evaluate the groundwater contribution to the indirect emissions of N2O because this will help to better constraint the N2O global budget and, consequently, the N budget. [less ▲]

Detailed reference viewed: 42 (0 ULg)
Peer Reviewed
See detailProtecting Assets Under Non-Parametric Market Conditions
Choffray, Jean-Marie ULg; Pahud de Mortanges, Charles ULg

in Longin, François (Ed.) Extreme Events in Finance: A Handbook of Extreme Value Theory and its Applications (2017)

Under non-parametric market conditions, investors usually become more concerned about the return of their money than about the return on their money. Protecting assets becomes the surest if not the only ... [more ▼]

Under non-parametric market conditions, investors usually become more concerned about the return of their money than about the return on their money. Protecting assets becomes the surest if not the only path to survival and growth. High frequency trading systems, over leveraged shadow entities, flash crashes, and stealth central bank actions, to name a few, contribute to create a “Rumsfeldian” type of world in which decision makers have to cope not only with “Known knowns” – things they know that they know – but also with “Unknown unknowns” – things they don’t know that they don’t know! The goal of this chapter is to explore such a conceptual model of the “Unknown” and to derive from it a concise and coherent set of battle-tested heuristics aimed at designing effective investment strategies to protect assets. [less ▲]

Detailed reference viewed: 666 (59 ULg)
Full Text
Peer Reviewed
See detailA Machine Learning-Based Approximation of Strong Branching
Marcos Alvarez, Alejandro ULg; Louveaux, Quentin ULg; Wehenkel, Louis ULg

in INFORMS Journal on Computing (2017), 29(1), 185-195

We present in this paper a new generic approach to variable branching in branch-and-bound for mixed- integer linear problems. Our approach consists in imitating the decisions taken by a good branching ... [more ▼]

We present in this paper a new generic approach to variable branching in branch-and-bound for mixed- integer linear problems. Our approach consists in imitating the decisions taken by a good branching strategy, namely strong branching, with a fast approximation. This approximated function is created by a machine learning technique from a set of observed branching decisions taken by strong branching. The philosophy of the approach is similar to reliability branching. However, our approach can catch more complex aspects of observed previous branchings in order to take a branching decision. The experiments performed on randomly generated and MIPLIB problems show promising results. [less ▲]

Detailed reference viewed: 126 (10 ULg)
Full Text
Peer Reviewed
See detailMolecular-Based Recursive Partitioning Analysis Model for Glioblastoma in the Temozolomide Era: A Correlative Analysis Based on NRG Oncology RTOG 0525.
Bell, Erica Hlavin; Pugh, Stephanie L.; McElroy, Joseph P. et al

in JAMA Oncology (2017)

Importance: There is a need for a more refined, molecularly based classification model for glioblastoma (GBM) in the temozolomide era. Objective: To refine the existing clinically based recursive ... [more ▼]

Importance: There is a need for a more refined, molecularly based classification model for glioblastoma (GBM) in the temozolomide era. Objective: To refine the existing clinically based recursive partitioning analysis (RPA) model by incorporating molecular variables. Design, Setting, and Participants: NRG Oncology RTOG 0525 specimens (n = 452) were analyzed for protein biomarkers representing key pathways in GBM by a quantitative molecular microscopy-based approach with semiquantitative immunohistochemical validation. Prognostic significance of each protein was examined by single-marker and multimarker Cox regression analyses. To reclassify the prognostic risk groups, significant protein biomarkers on single-marker analysis were incorporated into an RPA model consisting of the same clinical variables (age, Karnofsky Performance Status, extent of resection, and neurologic function) as the existing RTOG RPA. The new RPA model (NRG-GBM-RPA) was confirmed using traditional immunohistochemistry in an independent data set (n = 176). Main Outcomes and Measures: Overall survival (OS). Results: In 452 specimens, MGMT (hazard ratio [HR], 1.81; 95% CI, 1.37-2.39; P < .001), survivin (HR, 1.36; 95% CI, 1.04-1.76; P = .02), c-Met (HR, 1.53; 95% CI, 1.06-2.23; P = .02), pmTOR (HR, 0.76; 95% CI, 0.60-0.97; P = .03), and Ki-67 (HR, 1.40; 95% CI, 1.10-1.78; P = .007) protein levels were found to be significant on single-marker multivariate analysis of OS. To refine the existing RPA, significant protein biomarkers together with clinical variables (age, Karnofsky Performance Status, extent of resection, and neurological function) were incorporated into a new model. Of 166 patients used for the new NRG-GBM-RPA model, 97 (58.4%) were male (mean [SD] age, 55.7 [12.0] years). Higher MGMT protein level was significantly associated with decreased MGMT promoter methylation and vice versa (1425.1 for methylated vs 1828.0 for unmethylated; P < .001). Furthermore, MGMT protein expression (HR, 1.84; 95% CI, 1.38-2.43; P < .001) had greater prognostic value for OS compared with MGMT promoter methylation (HR, 1.77; 95% CI, 1.28-2.44; P < .001). The refined NRG-GBM-RPA consisting of MGMT protein, c-Met protein, and age revealed greater separation of OS prognostic classes compared with the existing clinically based RPA model and MGMT promoter methylation in NRG Oncology RTOG 0525. The prognostic significance of the NRG-GBM-RPA was subsequently confirmed in an independent data set (n = 176). Conclusions and Relevance: This new NRG-GBM-RPA model improves outcome stratification over both the current RTOG RPA model and MGMT promoter methylation, respectively, for patients with GBM treated with radiation and temozolomide and was biologically validated in an independent data set. The revised RPA has the potential to contribute to improving the accurate assessment of prognostic groups in patients with GBM treated with radiation and temozolomide and to influence clinical decision making. Trial Registration: clinicaltrials.gov Identifier: NCT00304031. [less ▲]

Detailed reference viewed: 22 (0 ULg)
Full Text
Peer Reviewed
See detailConcise Reviews: Regeneration in Mammalian Cochlea Hair Cells: Help from Supporting Cells Transdifferentiation.
Franco, Benedicte; Malgrange, Brigitte ULg

in Stem cells (Dayton, Ohio) (2017)

It is commonly assumed that mammalian cochlear cells do not regenerate. Therefore, if hair cells are lost following an injury, no recovery could occur. However, during the first postnatal week, mice ... [more ▼]

It is commonly assumed that mammalian cochlear cells do not regenerate. Therefore, if hair cells are lost following an injury, no recovery could occur. However, during the first postnatal week, mice harbor some progenitor cells that retain the ability to give rise to new hair cells. These progenitor cells are in fact supporting cells. Upon hair cells loss, those cells are able to generate new hair cells both by direct transdifferentiation or following cell cycle re-entry and differentiation. However, this property of supporting cells is progressively lost after birth. Here, we review the molecular mechanisms that are involved in mammalian hair cell development and regeneration. Manipulating pathways used during development constitute good candidates for inducing hair cell regeneration after injury. Despite these promising studies, there is still no evidence for a recovery following hair cells loss in adult mammals. Stem Cells 2017. [less ▲]

Detailed reference viewed: 14 (1 ULg)
Full Text
Peer Reviewed
See detailInfluence of the crustal magnetic field on the Mars aurora electron flux and UV brightness
Bisikalo, D. V.; Shematovich, V. I.; Gérard, Jean-Claude ULg et al

in Icarus (2017), 282

Observations with the SPICAM instrument on board Mars Express have shown the occasional presence of localized ultraviolet nightside emissions associated with enhanced energetic electron fluxes. These ... [more ▼]

Observations with the SPICAM instrument on board Mars Express have shown the occasional presence of localized ultraviolet nightside emissions associated with enhanced energetic electron fluxes. These features generally occur in regions with significant radial crustal magnetic field. We use a Monte-Carlo electron transport model to investigate the role of the magnetic field on the downward and upward electron fluxes, the brightness and the emitted power of auroral emissions. Simulations based on an ASPERA-3 measured auroral electron precipitation indicate that magnetic mirroring leads to an intensification of the energy flux carried by upward moving electrons- from about 20% in the absence of crustal magnetic field up to 33-78% when magnetic field is included depending on magnetic field topology. Conservation of the particle flux in a flux tube implies that the presence of the B-field does not appreciably modify the emission rate profiles for an initially isotropic pitch angle distribution. However, we find that crustal magnetic field results in increase of the upward electron flux, and, consequently, in reduction of the total auroral brightness for given energy flux of precipitating electrons. [less ▲]

Detailed reference viewed: 17 (3 ULg)
Full Text
Peer Reviewed
See detailMars Topography Investigated Through the Wavelet Leaders Method: a Multidimensional Study of its Fractal Structure
Deliège, Adrien ULg; Kleyntssens, Thomas ULg; Nicolay, Samuel ULg

in Planetary and Space Science (2017), 136C

This work examines the scaling properties of Mars topography through a wavelet-based formalism. We conduct exhaustive one-dimensional (both longitudinal and latitudinal) and two-dimensional studies based ... [more ▼]

This work examines the scaling properties of Mars topography through a wavelet-based formalism. We conduct exhaustive one-dimensional (both longitudinal and latitudinal) and two-dimensional studies based on Mars Orbiter Laser Altimeter (MOLA) data using the multifractal formalism called Wavelet Leaders Method (WLM). This approach shows that a scale break occurs at approximately 15 km, giving two scaling regimes in both 1D and 2D cases. At small scales, these topographic profiles mostly display a monofractal behavior while a switch to multifractality is observed in several areas at larger scales. The scaling exponents extracted from this framework tend to be greater at small scales. In the 1D context, these observations are in agreement with previous works and thus suggest that the WLM is well-suited for examining scaling properties of topographic fields. Moreover, the 2D analysis is the first such complete study to our knowledge. It gives both a local and global insight on the scaling regimes of the surface of Mars and allows to exhibit the link between the scaling exponents and several famous features of the Martian topography. These results may be used as a solid basis for further investigations of the scaling laws of the Red planet and show that the WLM could be used to perform systematic analyses of the surface roughness of other celestial bodies. [less ▲]

Detailed reference viewed: 37 (21 ULg)
See detailMamlūk Cairo: A Crossroad for Embassies
Bauden, Frédéric ULg; Dekkiche, Malika

Book published by Brill Academic Publishers (2017)

Detailed reference viewed: 149 (7 ULg)
Full Text
Peer Reviewed
See detailHow does forest cover impact water flows and ecosystem services? Insights from real-life catchments in Wallonia (Belgium)
Brogna, Delphine; Vincke, Caroline; Brostaux, Yves ULg et al

in Ecological Indicators (2017), 72

While planet boundaries are being crossed and ecosystems degraded, the Ecosystem Service (ES) conceptrepresents a potential decision-making tool for improved natural resources management. The main aimof ... [more ▼]

While planet boundaries are being crossed and ecosystems degraded, the Ecosystem Service (ES) conceptrepresents a potential decision-making tool for improved natural resources management. The main aimof this paper is to assess the impact of forest cover on water related ES in Wallonia (Belgium) in termsof quantity and timing. We developed an approach based on easily accessible data, monitored in severalcountries and using straightforward statistical methods. This led us to study ES at “real-life” catchmentsscale: 22 catchments – from 30 to 250 km2– with mixed land covers were studied. We approached thewater supply and flood protection services through 5 indicators extracted from 10 hydrological years(2005–2014) discharge data series. These were computed annually and seasonally (vegetation periodfrom March to September and “non-vegetation” period the rest of the year). The water supply wasassessed through the specific volume Vs, the baseflow index BFI and the specific discharge exceeded95% of the time Q95s whereas the flood protection service was approached through the specific dis-charge exceeded 5% of the time Q05s and the flashiness index FI. Our study gives two main insights. First,statistical analyses show that forest cover negatively impact water supply when studying annual and“non-vegetation” period flows in general (Vs) but positively when studying low flows (Q95s). Regardingflood protection a slightly negative impact of forest cover on high flows (Q05s) was highlighted in the“non-vegetation” period. Results also show a negative impact of forests annually and in the vegetationperiod on the flashy behaviour of the catchment thus a positive impact on the flood protection ES. The“year” effect is overall highly significant testifying the importance of climatic factors. Rainfall is oftensignificant and can be considered as a main driver of these ES. Secondly, analyzing the quality of themodels produced and the results overall we assume that other variables characterizing the catchmentssuch as topography or soil types do play a significant role in the delivery of these ES. This questions theuse of land cover proxies in assessing and mapping of hydrological ES at a complex landscape scale. Wethus recommend further research to keep improving land cover proxies if they are used. [less ▲]

Detailed reference viewed: 52 (13 ULg)
Peer Reviewed
See detailA Reconstructed Qarā Qoyūnlū Letter
Bauden, Frédéric ULg

in Bauden, Frédéric; Dekkiche, Malika (Eds.) Mamlūk Cairo: A Crossroad for Embassies (2017)

Detailed reference viewed: 52 (6 ULg)
Peer Reviewed
See detailLa bibliothèque d'Antoine Galland
Bauden, Frédéric ULg

in Bauden, Frédéric; Waller, Richard (Eds.) Antoine Galland (1646-1715) et son Journal. Actes du colloque international organisé à l’Université de Liège (16-18 janvier 2015) à l’occasion du tricentenaire de sa mort (2017)

Detailed reference viewed: 14 (0 ULg)