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See detailThe role of segmentation and investor recognition through the lens of cross-listing activity
Mouchette, Xavier ULg; Muller, Aline ULg; Carrieri, Francesca

Conference (2014, June)

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See detailThe role of segmentation and investor recognition through the lens of cross-listing activity
Mouchette, Xavier ULg; Carrieri, Francesca; Muller, Aline ULg

Conference (2014, June)

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See detailThe role of segmentation and investor recognition through the lens of cross‐listing activity
Mouchette, Xavier ULg; Muller, Aline ULg; Carrieri, Francesca

Conference (2014, June)

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See detailPrise en charge de l'hypertension artérielle du patient âgé
XHIGNESSE, Patricia ULg; Saint-Remy, Annie ULg; Krzesinski, Jean-Marie ULg

in Revue Médicale de Liège (2014), 69(5-6), 294-300

High blood pressure is very frequent in the elderly; it represents a real threat for the patient’s health and a source of huge costs for the economic system. Systolic hypertension is the most frequent ... [more ▼]

High blood pressure is very frequent in the elderly; it represents a real threat for the patient’s health and a source of huge costs for the economic system. Systolic hypertension is the most frequent form observed in the old, due to large arteries stiffness. Antihypertensive therapy has proven effective to decrease significantly the cardiovascular morbi-mortality and total mortality in this population. A non pharmacological approach is also very useful, but should not be too restrictive. Blood pressure target in patients older than 65 (and, particularly, in octogenarians) is 150/80 mmHg. Blood pressure should be checked in the upright position before changing the drug dosage. The first line therapy in the old should generally be a calcium channel antagonist or a low dose diuretic. [less ▲]

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See detailLe ciel étoilé d’Isis et d’Héphaïstos à Memphis
Veymiers, Richard ULg

Conference (2014, June)

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See detailMeandering flows in rectangular shallow reservoirs
Peltier, Yann ULg; Erpicum, Sébastien ULg; Dewals, Benjamin ULg

Report (2014)

During this research, previously unexplored meandering flows in free-surface rectangular shallow reservoirs were investigated theoretically, experimentally and numerically. For the first time, a complete ... [more ▼]

During this research, previously unexplored meandering flows in free-surface rectangular shallow reservoirs were investigated theoretically, experimentally and numerically. For the first time, a complete description of the hydrodynamics of the meandering flows was obtained from laboratory experiments. An innovative procedure for the characterisation of the physics of the flow was developed based on several techniques, including Large Scale Particle Image Velocimetry (LSPIV), Proper Orthogonal Decomposition (POD) and a new topology algorithm. This research provides new insights into these fascinating meandering flows, of high practical relevance in civil and environmental engineering. Six papers were written and, so far, five of them have been accepted for publication (two in international journals and three in peer-reviewed international conference proceedings). [less ▲]

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See detailSynthèse bibliographique sur la mobilité des éléments traces dans les sols et l’utilisation de la stabilisation physico-chimique comme technique de gestion in situ des sites contaminés
Liénard, Amandine ULg; Colinet, Gilles ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2014), 18(2), 273-289

Industrial activities have deeply impacted the quality of biophysical environment at places. This review focuses on consequences of soil contaminations by metallic trace elements: what conditions the ... [more ▼]

Industrial activities have deeply impacted the quality of biophysical environment at places. This review focuses on consequences of soil contaminations by metallic trace elements: what conditions the mobility of contaminants in soils and what are the remediation practices based upon physico-chemical stabilization? This technique is an in situ remediation which aims at limiting the dispersion of metals in the environment by use of soil conditioners and amendments in contaminated sites. First of all, we reviewed the concepts of mobility of trace elements and their indicators. Then, we compiled the different kinds of amendments applied to stabilize contaminants in soils and the processes involved. [less ▲]

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See detailStereoselective synthesis of peptidoglycan fragments on solid support
Simon, Justine ULg; Lamborelle, Nicolas ULg; Joris, Bernard ULg et al

Poster (2014, June)

The mammalian proteins, Nod1 and Nod2, are able to recognize peptidoglycan motifs during bacterial infection. Interestingly, Nod1 is a detector of peptides and muropeptides containing the meso-2,6 ... [more ▼]

The mammalian proteins, Nod1 and Nod2, are able to recognize peptidoglycan motifs during bacterial infection. Interestingly, Nod1 is a detector of peptides and muropeptides containing the meso-2,6-diaminopimelic acid (m-A2pm), a non-proteinogenic amino acid found in Gram- bacteria. In this work, we describe a synthesis of peptidoglycan motifs entirely on solid support. Solid-Phase Peptide Synthesis (SPPS), Cross Metathesis (CM) and sugar chemistry are three methods to anchor respectively amino acids, m-A2pm and sugars derivatives on a resin as solid support. [less ▲]

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See detailAnalysis versus synthesis for trending of gas-path measurement time series
Borguet, Sébastien ULg; Léonard, Olivier ULg; Dewallef, Pierre ULg

in Proceedings of ASME Turbo Expo 2014 (2014, June)

Gas-path measurements used to assess the health condition of an engine are corrupted by noise. Generally, a data cleaning step occurs before proceeding with fault detection and isolation. Classical linear ... [more ▼]

Gas-path measurements used to assess the health condition of an engine are corrupted by noise. Generally, a data cleaning step occurs before proceeding with fault detection and isolation. Classical linear filters such as the exponentially weighted moving average filter are traditionally used for noise removal. Unfortunately, these low-pass filters distort trend shifts indicative of faults, which increases the detection delay. The present paper investigates two new approaches to non-linear filtering of time series. On one hand, the synthesis approach reconstructs the signal as a combination of elementary signals chosen from a pre-defined library. On the other hand, the analysis approach imposes a constraint on the shape of the signal (e.g., piecewise constant). Both approaches incorporate prior information about the signal in a different way, but they lead to trend filters that are very capable at noise removal while preserving at the same time sharp edges in the signal. This is highlighted through the comparison with a classical linear filter on a batch of synthetic data representative of typical engine fault profiles. [less ▲]

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See detailThe EU and Brazil in a changing world: strategic partners or competitors?
Santander, Sébastian ULg

in Smith, Michael; Keukeleire, Stephan; Vanhoonacker, Sophie (Eds.) The Diplomatic System of the European Union Evolution, Change and Challenges (2014)

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See detailÉtude des changements de circulation au-dessus de l'océan Austral en été
Belleflamme, Alexandre ULg; Fettweis, Xavier ULg; Erpicum, Michel ULg

in Camberlin, Pierre; Richard, Yves (Eds.) Actes du XXVIIème colloque de l'Association de Climatologie - Climat : système & interactions (2014, June)

Over the five last decades, the reanalyses (ERA and NCEP/NCAR) show a strengthening of the pressure gradient between the southern hemisphere subtropical anticyclone belt and the southern circumpolar lows ... [more ▼]

Over the five last decades, the reanalyses (ERA and NCEP/NCAR) show a strengthening of the pressure gradient between the southern hemisphere subtropical anticyclone belt and the southern circumpolar lows during summer. With the help of an automatic circulation type classification, we show that the strengthening of the pressure gradient is generalised to all circulation types and, paradoxically, it does not cause circulation changes. It is probably implied by the strengthening of the temperature gradient between the tropics and the South Pole, without consequences on the general circulation. Our classification also allows a successful comparison between the two reanalyses in a region where the observation data are rare. [less ▲]

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See detailLe "péril jaune" en RDC : mythe ou réalité ?
Wintgens, Sophie ULg; Kabamba, Bob ULg

in Santander, Sébastian (Ed.) L’Afrique, nouveau terrain de jeu des émergents (2014)

L’influence de la Chine en république démocratique du Congo (RDC) se caractérise par son caractère tardif mais fulgurant, au regard d’une présence chinoise historiquement forte en Afrique subsaharienne ... [more ▼]

L’influence de la Chine en république démocratique du Congo (RDC) se caractérise par son caractère tardif mais fulgurant, au regard d’une présence chinoise historiquement forte en Afrique subsaharienne. Son implantation offensive en RDC résulte d’une convergence d’intérêts entre un État chinois en quête de matières premières et de terres arables pour assurer son développement économique et sa stabilité politique, et un État congolais en (re)construction résolument acquis, depuis l’élection du président Joseph Kabila, au modèle de développement chinois fondé sur la séparation volontaire entre objectifs économiques et réformes politiques (prêts inconditionnés, aide déliée). En consacrant l’accroissement rapide des relations commerciales sino-congolaises, le partenariat stratégique Chine-Afrique, scellé en 2006 lors du troisième Forum de coopération sino-africain, participe plus largement de la remise en cause du rôle des puissances traditionnellement influentes dans la région. Au-delà de la concurrence économique induite vis-à-vis des États-Unis, du Japon et des institutions financières internationales au sein desquelles elle est largement représentée, l’Europe assiste plus singulièrement à la remise en question de son leadership régional et à la dépréciation normative de sa politique développementale. Entre émancipation et hégémonie, cet article vise à mettre au jour les enjeux stratégiques inhérents à l’impact du "facteur chinois" en RDC. [less ▲]

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See detailDoes the achievement of an intermediate glycemic target reduce organ failure and mortality? A post-hoc analysis of the Glucontrol Trial
Penning, Sophie ULg; Chase, J. Geoffrey; Preiser, Jean-Charles et al

in Journal of Critical Care (2014)

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See detailInhibition of PDH Kinase as a new therapeutic target for Age-related Macular Degeneration (AMD)
Arslan, Deniz ULg; Pirotte, Bernard ULg; De Tullio, Pascal ULg et al

Poster (2014, June)

Metabolomics is one of the most recent technologies in the world of Omics sciences. It aims at studying metabolome, which is composed of small molecular weight organic molecules (called metabolites) of a ... [more ▼]

Metabolomics is one of the most recent technologies in the world of Omics sciences. It aims at studying metabolome, which is composed of small molecular weight organic molecules (called metabolites) of a cell, an organism or a biological system. This approach gives rise to a growing number of applications in many areas, such as biomarkers discovery, clinical studies, drug efficacy and toxicity evaluation, diagnostic tools, quality control. One of the most interesting features of metabolomics is its capability to extract biochemical information reflecting biological events and then to be a powerful tool in the knowledge of the aetiology of some pathologies. Indeed, it is clear that every disease could alter more or less drastically the metabolic profile of the patients. Then a metabolomics approach could highlight the biochemical pathways affected and could allow the identification of new putative therapeutic strategies or targets that could be useful in a new drug discovery strategy. As proteomics, metabolomics approach represents a new and powerful tool for Medicinal Chemistry. Age-related Macular Degeneration (AMD) is a leading cause of vision loss in the western world among people aged 50 or older. 90% of all vision loss due to AMD results from the exudative form, which is characterized by choroidal neovascularization (CNV). Age-related changes that induce pathologic CNV are incompletely understood. A successful application of anti-VEGF approaches in the clinic is obviously a turning point in AMD treatment. Nevertheless, despite such important advances, critical issues remain to be addressed. To better understand the aetiology of this pathology, we used and improved a murine model of laser-induced choroidal neovascularization and applied a 1H NMR metabolomics study. This approach leads to the emergence of different putative biomarkers and to the validation of the CNV model for an experimental study of AMD. Among these “biomarkers”, lactate appears to be clearly involved in the development of AMD. The modulation of their plasma concentration by treatment of the animals with synthetic compounds and more specifically Pyruvate DesHydrogenase Kinase inhibitors (PDHK) significantly decrease the impact of laser induced CNV. Starting from these results, the development of new PDHK inhibitors could open the way to innovative treatment opportunities in AMD disease. [less ▲]

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See detailSocial Security and Economic Integration
Artige, Lionel ULg; Dedry, Antoine ULg; Pestieau, Pierre ULg

in Economics Letters (2014), 123(June), 318-322

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See detailThe Call for project proposals « Let’s live my village »: between free interpretations and compulsory readings regarding innovation and convivial village ambiance in Wallonia.
Schmitz, Serge ULg

in Les campagnes: espaces d'innovation dans un monde urbain (2014, June)

The paper scrutinizes 186 rural development projects selected on the short list of the first and second “Lets’ live my village!” calls. It examines trends concerning rural community life and the identity ... [more ▼]

The paper scrutinizes 186 rural development projects selected on the short list of the first and second “Lets’ live my village!” calls. It examines trends concerning rural community life and the identity of the leaders/brokers. It pays attention to the way that associations define rurality. Question 14 of the application form « Does your association act in rural areas? Explain” is the main source of information for content analysis and contingency tables [less ▲]

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See detailPhysical controls on the storage of methane in landfast sea ice
Zhou, Jiayun ULg; Tison, J.-L.; Carnat, G. et al

in The Cryosphere (2014), 8(3), 1019-1029

We report on methane (CH4) dynamics in landfast sea ice, brine and under-ice seawater at Barrow in 2009. The CH4 concentrations in under-ice water ranged between 25.9 and 116.4 nmol L-1sw, indicating a ... [more ▼]

We report on methane (CH4) dynamics in landfast sea ice, brine and under-ice seawater at Barrow in 2009. The CH4 concentrations in under-ice water ranged between 25.9 and 116.4 nmol L-1sw, indicating a supersaturation of 700 to 3100 % relative to the atmosphere. In comparison, the CH4 concentrations in sea ice, ranged between 3.4 and 17.2 nmol L-1ice, and the deduced CH4 concentrations in brine, between 13.2 and 677.7 nmol L-1brine. We investigated on the processes explaining the difference in CH4 concentrations between sea ice, brine and the under-ice water, and suggest that biological controls on the storage of CH4 in ice was minor in comparison to the physical controls. Two physical processes regulated the storage of CH4 in our landfast ice samples: bubble formation within the ice and sea ice permeability. Gas bubble formation from solubility changes had favoured the accumulation of CH4 in the ice at the beginning of ice growth. CH4 retention in sea ice was then twice as efficient as that of salt; this also explains the overall higher CH4 concentrations in brine than in the under-ice water. As sea ice thickened, gas bubble formation became less efficient, CH4 was then mainly trapped in the dissolved state. The increase of sea ice permeability during ice melt marked the end of CH4 storage. [less ▲]

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