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See detailTendances générales de l'agriculture à Courcelles: vers quel avenir?
Bousbaine, Antonia ULg

Conference given outside the academic context (2017)

L'évolution de l'agriculture dans une commune du Hainaut : Courcelles, pointe du doigt les pertes significatives de cette agriculture, cependant la diversification pourrait constituer une solution, avec ... [more ▼]

L'évolution de l'agriculture dans une commune du Hainaut : Courcelles, pointe du doigt les pertes significatives de cette agriculture, cependant la diversification pourrait constituer une solution, avec la mise en place de la ceinture Aliment Terre de Charleroi Métropole [less ▲]

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See detailLa revue L’Ossature métallique et le débat de l’architecture dans l’entre-deux- guerres
Charlier, Sébastien ULg

Conference (2017, April 25)

Publiée à Bruxelles dès 1932, L’Ossature métallique est éditée par le Centre belgo-luxembourgeois d’information de l’acier pour faire face à la crise économique qui frappe durement l’industrie ... [more ▼]

Publiée à Bruxelles dès 1932, L’Ossature métallique est éditée par le Centre belgo-luxembourgeois d’information de l’acier pour faire face à la crise économique qui frappe durement l’industrie sidérurgique belge depuis 1929. Le mensuel traduit la volonté de l’industrie de disposer d’un organe d’information puissant relayant les dernières nouveautés en matière de constructions en acier. La revue se destine d’abord aux ingénieurs et propose de nombreuses études techniques (théories, calculs, essais) et des articles sur le rôle du métal dans le génie civil ou dans les moyens de transports (voitures de chemin de fer, locomotives, bateaux…). Très vite, L’Ossature métallique prend conscience des nouveaux marchés à toucher et prend pied dans le champ de l’architecture en proposant des articles sur des bâtiments à structure métallique. Puisant d’abord ses articles dans la presse internationale, la revue peut bientôt compter sur des articles originaux témoignant d’un réseau d’auteurs étendus et aux profils variés. Après avoir situé l’organe dans le fascinant bouillonnement des revues d’architecture de l’entre-deux-guerres, l’exposé montrera, à travers une sélection d’articles traitant en priorité de réalisations situées en Wallonie, de la variété des sujets traités par L’Ossature métallique. De la petite maison individuelle à l’immeuble à appartements en passant par les infrastructures publiques ou les bâtiments industriels, l’exposé proposera quelques expressions de l’architecture métallique en Belgique. [less ▲]

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See detailLe charme irrésistible de Cléopâtre
Berthelet, Yann ULg

Conference given outside the academic context (2017)

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See detailLymphatic vasculature requires estrogen receptor alpha signaling to protect from lymphedema
Morfoisse, Florent ULg

Conference (2017, April 24)

Rationale: Estrogen play a crucial role on the cardiovascular system and, particularly, on the vascular endothelium. However, the effect of estrogen on the lymphatic system has been poorly investigated ... [more ▼]

Rationale: Estrogen play a crucial role on the cardiovascular system and, particularly, on the vascular endothelium. However, the effect of estrogen on the lymphatic system has been poorly investigated. Objective: We aimed to demonstrate the protective effect of the 17 estradiol (E2), the most potent endogenous estrogen in lymphedema, a lymphatic dysfunction, which results in a massive fluid and fat accumulation. Methods and Results: Immunohistochemistry revealed that high doses of E2 modified skin microenvironment and stimulated lymphangiogenesis. E2 activates lymphatic endothelium through a transcriptional activation induced by its receptor ER. Using an original model of secondary lymphedema, we found a protective effect of E2 that prevents limb swelling. Loss of ER function using selective estrogen modulator (SERM) and in Tie2 Cre(+); ER-/- mice lead to a disruption of the lymphatic network promoting lymphedema. This effect was associated with a remodeling of LEC, an inhibition of gene expression, and ERK, but not AKT E2-induced phosphorylation. Conclusion: These findings reveal a new facet of the influence of estrogens in the management of the lymphatic system in pathological condition and provides more evidences that secondary lymphedema is not only a side effect of surgery, but is worsen by hormone therapy. [less ▲]

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See detailAvatars et actualité de la phénoménotechnique
Pieron, Julien ULg

Conference (2017, April 24)

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See detailDose-dependent effect of Estetrol on Angiogenesis and Tumor Growth
Gallez, Anne ULg; Blacher, Silvia ULg; Lenfant, Françoise et al

Poster (2017, April 24)

Hormone replacement therapies (HRT) based on estrogen preparations are the most powerful treatments to prevent menopause symptoms. However, they are associated to an increased risk of breast cancer and ... [more ▼]

Hormone replacement therapies (HRT) based on estrogen preparations are the most powerful treatments to prevent menopause symptoms. However, they are associated to an increased risk of breast cancer and they sustain the development of Estrogen Receptor α-positive tumors (ERα+). In addition, we have previously observed that estradiol (E2) can promote the growth of ERα-negative (ERα-) tumors, by increasing tumor angiogenesis that subsequently improves oxygen and nutrients delivery, thereby preventing hypoxia and necrosis. To identify new and safe drugs for the development of HRT presenting a better benefit/risk ratio, it is therefore necessary to evaluate the potential impact of new candidates on both ERα+ and ERα- tumors. In this context, estetrol (E4), a natural estrogen exclusively produced by the fetal liver, is a promising candidate. [less ▲]

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See detailCanopy aerodynamic distance (z-d) estimation and impact on eddy covariance measurements
Hurdebise, Quentin ULg; De Ligne, Anne ULg; Vincke, Caroline et al

in Geophysical Research Abstracts 2017 (2017, April 24)

Understanding if and how the spatial and temporal variability of the surrounding environment affects turbulence is essential for long-term eddy covariance measurements above growing and heterogeneous ... [more ▼]

Understanding if and how the spatial and temporal variability of the surrounding environment affects turbulence is essential for long-term eddy covariance measurements above growing and heterogeneous ecosystems. It requires characterizing the surrounding environment. One way to achieve this is to analyse the canopy aerodynamic distance, which is the difference between measurement height (z) and displacement height (d). In this study, twenty years of eddy covariance measurements from the Vielsalm Terrestrial Observatory, a site located in a mixed temperate forest, were used. Canopy aerodynamic distance (z-d) estimates were obtained using two micrometeorological methods: the first one, which is original so far as we know, was based on analysing sensible heat cospectra; the second one was derived from the wind speed profile equation. Canopy height estimates based on inventories were used to validate both methods. The micrometeorological methods allowed the z-d variations due to changes in canopy or measurement height to be detected. In addition, the results obtained using the two methods were well correlated, spatially and temporally, with the z-d derived from canopy height measurements. The micrometeorological approaches used could therefore be a promising tool for investigating z-d variability at a high directional and temporal resolution. Questions remain, however, particularly with regard to the variability observed that cannot be explained by canopy or measurement height variation. Forest management practices and the non-fulfilment of similarity relationships were suspected to be the main explanatory factors. [less ▲]

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See detailMomentum, sensible heat and CO2 correlation coefficient: what can we learn from 20 years of eddy covariance measurements
Hurdebise, Quentin ULg; De Ligne, Anne ULg; Vincke, Caroline et al

Poster (2017, April 24)

Long-term data series of carbon dioxide and other gas exchanges between terrestrial ecosystems and atmosphere become more and more numerous. Long-term analyses of such exchanges require a good ... [more ▼]

Long-term data series of carbon dioxide and other gas exchanges between terrestrial ecosystems and atmosphere become more and more numerous. Long-term analyses of such exchanges require a good understanding of measurement conditions during the investigated period. Independently of climate drivers, measurements may indeed be influenced by measurement conditions themselves subjected to long-term variability due to vegetation growth or set-up changes. The present research refers to the Vielsalm Terrestrial Observatory (VTO) an ICOS candidate site located in a mixed forest (beech, silver fir, Douglas fir, Norway spruce) in the Belgian Ardenne. Fluxes of momentum, carbon dioxide and sensible heat have been continuously measured there by eddy covariance for more than 20 years. During this period, changes in canopy height and measurement height occurred. The correlation coefficients (for momemtum, sensible heat and CO2) and the normalized standard deviations measured for the past 20 years at the Vielsalm Terrestrial Observatory (VTO) were analysed in order to define how the fluxes, independently of climate conditions, were affected by the surrounding environment evolution, including tree growth, forest thinning and tower height change. A relationship between canopy aerodynamic distance and the momentum correlation coefficient was found which is characteristic of the roughness sublayer, and suggests that momentum transport processes were affected by z-d. In contrast, no relationship was found for sensible heat and CO2 correlation coefficients, suggesting that the z-d variability observed did not affect their turbulent transport. There were strong differences in these coefficients, however, between two wind sectors, characterized by contrasted stands (height differences, homogeneity) and different hypotheses were raised to explain it. This study highlighted the importance of taking the surrounding environment variability into account in order to ensure the spatio-temporal consistency of datasets. [less ▲]

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See detailA terminology in General Practice / Family Medicine to represent non-clinical aspects for various usages
Jamoulle, Marc ULg; Grosjean, Julien; Ittoo, Ashwin ULg et al

in R. Randell et al. (Ed.) Informatics for Health: Connected Citizen-Led Wellness and Population Health (2017, April 24)

Abstract. The hereby proposed terminology called “Q-Codes” can be defined as an extension of the International Classification of Primary Care (ICPC-2). It deals with non-clinical concepts that are ... [more ▼]

Abstract. The hereby proposed terminology called “Q-Codes” can be defined as an extension of the International Classification of Primary Care (ICPC-2). It deals with non-clinical concepts that are relevant in General Practice/Family Medicine (GP/FM). This terminology is a good way to put an emphasis on underestimated topics such as Teaching, Patient issues or Ethics. It aims at indexing GP/FM documents such as congress abstracts and theses to get a more comprehensive view about the GP/FM domain. The 182 identified Q-Codes have been very precisely defined by a college of experts (physicians and terminologists) from twelve countries. The result is available on the Health Terminology/Ontology Portal (http://www.hetop.org/Q) and formatted in OWL-2 for further semantic considerations and will be used to index the 2016 WONCA World congress communications. [less ▲]

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See detailHow learning methods in anatomy allow a boost of visuospatial abilities for undergraduate students
Defaweux, Valérie ULg; Ernst, Denise; Dernier, Adrienne ULg et al

Poster (2017, April 24)

Because it is know that visuospatial abilities affect anatomy learning and that our students are heterogeneous related to these competences, it is essential to offer an educational strategy designed to ... [more ▼]

Because it is know that visuospatial abilities affect anatomy learning and that our students are heterogeneous related to these competences, it is essential to offer an educational strategy designed to specifically train and develop those skills at the beginning of the anatomy courses. We managed to offer various formative activities that improve visuospatial skills. [less ▲]

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See detailReduced Tillage generates higher N2O emissions: results of continuous chamber-based measurement in a winter wheat field.
Broux, François ULg; Lognoul, Margaux ULg; Theodorakopoulos, Nicolas et al

Poster (2017, April 24)

Agriculture is one of the most important contributors to GHG emission, notably through fertilized croplands. Though, few publications have studied simultaneously and through continuous measurement the N2O ... [more ▼]

Agriculture is one of the most important contributors to GHG emission, notably through fertilized croplands. Though, few publications have studied simultaneously and through continuous measurement the N2O and CO2 emissions in cultivated lands. We conducted this study to assess the effect of farming practices and climate on both N2O and CO2 emissions from a winter wheat crop. The experiment was held in an experimental field in the loamy region in Belgium from March 2016 till crop harvest in August 2016. The fluxes were measured on two nearby parcels in a winter wheat field with restitution of the residues from previous crop. For the past 8 years, one parcel was subjected to a Reduced tillage (RT, 10 cm depth) and the other one to a conventional tillage (CT, 25 cm depth). On each parcel, the emissions are assessed with homemade automated closed chambers. Measurement continuity and good temporal resolution (one mean flux every 4 hours) of the system allowed a fine detection and quantification of the emission peaks which usually represent the major part of N2O fluxes. In addition to gas fluxes, soil water content and temperature were measured continuously. Soil samples were taken regularly to determine soil pH, soil organic carbon and nitrogen pools (total, NO3- and NH4+) and study microbial diversity and nitrification/denitrification gene expression. Surprisingly, results showed N2O emissions twice as large in the RT parcel as in the CT parcel. On the contrary, less important CO2 emissions were observed under RT. Several emission peaks of N2O were observed during the measurement period. The peaks occurred after fertilization events and seemed to be triggered by an elevation of soil water content. Interesting links could be made between soil NH4-N and NO3-N pools and N2O emissions. Nitrification being the main process originating the fluxes was suggested on the one hand by the temporal evolution of nitrogen pools and N2O emissions and on the other hand by the relation between spatial variability of the emissions with the soil nitrate content. A comparison of the emissions between ST and CT and a discussion on peaks temporal dynamic, focusing on their intensity, duration and starting time will be presented. [less ▲]

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See detailSalinity impact on seed yield, polyphenols composition and antioxidant activity of Fennel (Foeniculum vulgarae Mill) extracts
Bettaieb Rebey, Ines; Bourgou, S.; Msaada, K. et al

Poster (2017, April 24)

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See detailGeomorphic and Hydrological challenges in Africa: implications for soil and water conservation
Vanmaercke, Matthias ULg; Poesen, Jean

Conference (2017, April 24)

Expected scenarios of climate change and population growth confront Africa with various important challenges related to food, water and energy security. Many of these challenges are closely linked to the ... [more ▼]

Expected scenarios of climate change and population growth confront Africa with various important challenges related to food, water and energy security. Many of these challenges are closely linked to the impacts of soil erosion and other geomorphic processes, such as reduced crop yields, sedimentation of reservoirs and reduced freshwater quality. Despite the urgency and extent of many of these challenges, the causes and dynamics of these processes and their impacts remain severely understudied. This becomes apparent when the availability of e.g. soil erosion and catchment sediment export measurements for Africa is compared to that of other continents. Nonetheless, a substantial amount of geomorphic research has been conducted in Africa. Many of this work dates back from several decades ago, and were often only reported in ‘gray literature’ (e.g. internal reports). Here we present an overview of our current state of knowledge on soil erosion and its implications in Africa. We discuss which geomorphic process rate measurements are currently available and what can be learned from these with respect to the challenged raised above. We especially focus on our current understanding about the effectiveness of soil and water conservation techniques at various spatial and temporal scales. Based on specific case-studies (e.g. in Ethiopia and Uganda) and a meta-analysis of previous work, we highlight some research gaps, research needs and research opportunities when aiming to use Africa’s soil and water resources sustainably and efficiently [less ▲]

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See detailDetermining RUSLE P-factors for stonebunds and trenches in rangeland and cropland, Northern Ethiopia
Taye, Gebeyehu; Poesen, Jean; Vanmaercke, Matthias ULg et al

Conference (2017, April 24)

The implementation of soil and water conservation (SWC) measures in the Ethiopian highlands is a top priority to reduce soil erosion rates and to enhance the sustainability of agroecosystem. Nonetheless ... [more ▼]

The implementation of soil and water conservation (SWC) measures in the Ethiopian highlands is a top priority to reduce soil erosion rates and to enhance the sustainability of agroecosystem. Nonetheless, the effectiveness of many of these measures for different hillslope and land use conditions remains currently poorly understood. As a result, the overall effects of these measures at regional or catchment scale remain hard to quantify. This study addresses this knowledge gap by determining the cover-management (C) and support practice (P) factors of the Revised Universal Soil Loss Equation (RUSLE), for commonly used SWC measures in semi-arid environments (i.e. stone bunds, trenches and a combination of both). Calculations were based on soil loss data collected with runoff plots in Tigray, northern Ethiopia (i.e. 21 runoff plots of 600 to 1000 m2 , monitored during 2010, 2011 and 2012). The runoff plots were installed in rangeland and cropland sites corresponding to a gentle (5%), medium (12%) and steep (16%) slope gradients. The C and P factors of the RUSLE were calculated following the recommended standard procedures. Results show that the C-factor for rangeland ranges from 0.31 to 0.98 and from 0.06 to 0.39 for cropland. For rangeland, this large variability is due to variations in vegetation cover caused by grazing. In cropland, C-factors vary with tillage practices and crop types. The calculated P-factors ranged from 0.32 to 0.74 for stone bunds, from 0.07 to 0.65 for trenches and from 0.03 to 0.22 for a combination of both stone bunds and trenches. This variability is partly due to variations in the density of the implemented measures in relation to land use (cropland vs rangeland) and slope angles. However, also annual variations in P factor values are highly significant. Especially trenches showed a very significant decline of effectiveness over time, which is attributable to their reduced static storage capacity as a result of sediment deposition (e.g. for trenches in rangeland: 0.07-0.13 in 2010 to 0.37-0.65 in 2012). Hence, the results of this work may not only help in better modelling and quantifying the average long-term impacts of SWC measures over larger areas, but also show the importance of considering temporal variations of the effectiveness of SWC measures. [less ▲]

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See detailCancer associated fibroblast-derived integrin α11 regulates PDGFRβ signaling to promote breast cancer progression
Primac, Irina ULg; Blacher, Silvia ULg; cimino, Jonathan et al

Conference (2017, April 24)

CAF-specific proteins can provide important prognostic markers and targets for anticancer drugs. Recently, integrin α11 (ITGA11) emerged as a new biomarker of CAFs. ITGA11 is mainly expressed by ... [more ▼]

CAF-specific proteins can provide important prognostic markers and targets for anticancer drugs. Recently, integrin α11 (ITGA11) emerged as a new biomarker of CAFs. ITGA11 is mainly expressed by mesenchymal cells and is correlated with fibroblast activation and matrix reorganization. While the role of ITGA11 in wound healing has been well described, only a very limited number of reports have assessed its role in the cancer disease. This research project aims to investigate the role of stromal ITGA11 in breast cancer. To analyze the in vivo effects of ITGA11 on tumor insurgence, growth and metastasis, we crossed the oncogenic MMTv-PyMT mice with the ITGA11 KO/WT mice, which develop spontaneously breast tumors. ITGA11 deletion strongly delayed tumor growth and metastasis in PyMT mouse model. ITGA11 was poorly expressed at early stages of the tumor progression and its expression was strongly increased in the late stage invasive carcinomas. Importantly, a reduced angiogenesis and collagen content was observed in tumors lacking of ITGA11. Furthermore, a strong co-localization between ITGA11 and PDGFRb, but not other CAF markers such as alpha smooth actin, was also observed within the tumor stroma, suggesting that ITGA11 defines a subpopulation of CAFs, which is not represented by myofibroblasts, but rather PDGFRb+ CAFs. For mechanistic investigation, CAFs and breast cancer cells were isolated from the PyMT model. ITGA11 co-immunoprecipitated with PDGFRb in the isolated CAFs and regulated its phosphorylation. Interestingly, ITGA11-deficient CAFs failed to promote CAF and cancer cell invasion, in contrast to WT CAFs in a spheroid invasion assay. A high throughput comparative proteomics analysis on CAF spheroids in 3D a system was next performed. Proteomics data identified several proteins with relevance in the cancer disease which were significantly modulated in CAFs through ITGA11 down-regulation. The top-ranking candidates are under validation and molecular pathways, which may link these targets and ITGA11 will be further analyzed in the in vitro models. Overall, these in vivo and in vitro data show that ITGA11 defines a PDGFRβ+ subpopulation of CAFs distinct from α-SMA+ myofibroblasts that promote tumor cell invasion and angiogenesis at late stages of carcinoma evolution. ITGA11 is a promising target within the stroma of breast cancer and further investigations of its molecular signaling pathways will be of great relevance. [less ▲]

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See detailTransfert sol-plante et Procédés de phytoremédiation (Memoris)
Liénard, Amandine ULg

Conference given outside the academic context (2017)

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See detailCharacterizing root system characteristics with Electrical resistivity Tomography: a virtual rhizotron simulation
Rao, Sathyanarayan; Ehosioke, Solomon ULg; Lesparre, Nolwenn et al

Conference (2017, April 24)

Electrical Resistivity Tomography (ERT) is more and more used for monitoring soil water content in a cropped soil. Yet, the impact of roots on the signal is often neglected and a topic of controversy. In ... [more ▼]

Electrical Resistivity Tomography (ERT) is more and more used for monitoring soil water content in a cropped soil. Yet, the impact of roots on the signal is often neglected and a topic of controversy. In several studies related to soil-root system, it has been showed that the measured root mass density statistically correlates with the electrical conductivity (EC) data obtained from ERT. In addition, some studies suggest that some roots are more electrically conductive than soil for most water content. Thus, higher EC of roots suggest that it might have a measurable impact on ERT signals. In this work, virtual rhizotrons are simulated using the software package called R-SWMS that solves water and solute transport in plant root-soil system, including root growth. The distribution of water content obtained from R-SWMS simulation is converted into EC data using pedo-physical models. The electrical properties of roots and rhizosphere are explicitly included in the EC data to form a conductivity map (CM) with a very detailed spatial resolution. Forward ERT simulations is then carried out for CM generated for various root architectures and soil conditions to study the impact of roots on ERT forward (current and voltage patterns) and inverse solutions. It is demonstrated that under typical injection schemes with lateral electrodes, root system is hardly measurable. However, it is showed that adding electrodes and constraints on the ERT inversion based on root architecture help quantifying root system mass and extent. [less ▲]

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