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See detailOptimizing the management of osteoarthritis-Transitioning evidence-based guidelines into practical guidance for real-world clinical practice
Reginster, Jean-Yves ULg; Cooper, C.

in Seminars in Arthritis & Rheumatism (2016), 45(4 Suppl), 1-2

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See detailThe role of diet and exercise and of glucosamine sulfate in the prevention of knee osteoarthritis: Further results from the PRevention of knee Osteoarthritis in Overweight Females (PROOF) study.
Runhaar, J.; DEROISY, Rita ULg; van Middelkoop, M. et al

in Seminars in Arthritis & Rheumatism (2016), 45(4 Suppl), 42-48

Background and objectives: The PRevention of knee Osteoarthritis in Overweight Females(PROOF) study (ISRCTN42823086) described a trend for a decrease in the incidence of kneeo steoarthritis (OA) by a ... [more ▼]

Background and objectives: The PRevention of knee Osteoarthritis in Overweight Females(PROOF) study (ISRCTN42823086) described a trend for a decrease in the incidence of kneeo steoarthritis (OA) by a tailored diet and exercise program (DEP)or by oral glucosamine sulfate in women at risk for the disease, using a composite clinical and/or radiological outcome. The aim of this updated post-hoc analysis was to re-assess the results according to more precise techniques and take advantage of the 2 x 2 factorial design. Methods: A total of 407 overweight( BMI > or egal 27kg/m2) women of 50–60 years of age with no diagnosis of knee OA were randomized to: (1) noDEP + placebo(Control, N = 102), (2) DEP + placebo (DEP, N = 101), (3) glucosamine sulfate + no DEP (GS, N = 102), and (4) DEP + glucosamine sulfate (DEP + GS, N = 102) and followed for 2.5 years, with standardized postero-anterior, semiflexed (MTP) view knee radiographs at baseline and end of the study. DEP consisted of a tailored low fat and/or low caloric diet and easy to implement physical activities. Glucosamine was given as oral crystalline glucosamine sulfate 1500 mg once daily ,double-blinded vs. placebo. Incident knee OA was defined as radiographic progression of >1mm minimum joint space narrowing (mJSN)in the medial tibiofemoral compartment, as previously assessed by the visual (manual) technique and by a new semi-automated method. Logistic regression analysis was used t ocalculate the odds ratio for the effect of the interventions. Results: After 2.5 years, 11.8% of control subjects developed knee OA. This incidence was decreased with glucosamine sulfate, either alone or in combination with the DEP, but not by the DEP alone. Since there was no statistical interaction between treatments, the 2x2 factorial design allowed analysis of patients receiving glucosamine sulfate (N = 204) vs. those not receiving it (N= 203), similarly for those on the DEP (N = 203) or not (N = 204). Glucosamine sulfate significantly decreased the risk of developing knee OA: odds ratio (OR) = 0.41(95% CI: 0.20–0.85, P = 0.02) by the manual JSN assessment method and OR = 0.42 (95% CI:0.20–0.92, P =0.03) by the semi-automated technique. Conversely, there was no decrease in risk with the DEP. Conclusions: Glucosamine sulfate decreased the risk of developing radiographic knee OA over 2.5 years in overweight, middle-aged women at risk, as determined by medial mJSN progression. Conversely a tailored diet and exercise program exerted no preventive effect, possibly because of the lower than expected effect on weigh tloss. [less ▲]

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See detailEfficacy and safety of hyaluronic acid in the management of osteoarthritis : Evidence from real-life setting trials and surveys.
Maheu, E.; Rannou, F.; Reginster, Jean-Yves ULg

in Seminars in Arthritis & Rheumatism (2016), 45(4 Suppl), 28-33

The European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) treatment algorithm recommends intra-articular (IA) hyaluronic acid (HA) for management of knee ... [more ▼]

The European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) treatment algorithm recommends intra-articular (IA) hyaluronic acid (HA) for management of knee osteoarthritis (OA) as second-line treatment in patients who remain symptomatic despite use of non-steroidal anti-inflammatory drugs (NSAIDs). This recommendation is based upon accumulating evidence that IA HA provides a significant benefit in knee OA. There is good evidence that IA HA injections reduce pain and increase function in knee OA, and the benefits are long-lasting as compared with IA corticosteroids. Evidence from real-life studies of repeat courses of IA HA demonstrates an improvement in pain or function lasting up to 40 months (12 months after the last injection cycle), a reduction in use of concomitant analgesia by up to 50%, and suggests that there may be a delay in the need for total knee replacement (TKR) of around 2 years. The clinical benefit of IA HA on knee OA may be 2-fold: (i) mechanical viscosupplementation of the joint (allowing lubrication and shock absorption) and (ii) the re-establishment of joint homeostasis through induction of endogenous HA production, which continues long after the exogenous injection has left the joint.The magnitude of the clinical effect may be different for different HA products, but this has not been proven so far and requires further investigation. IA HA injections are generally considered to be safe,although a slightly higher number of cases of local reactions and post-injection non-septic arthritis has been reported with high molecular weight cross-linked HAs. The use of IA HA in knee OA patients with mild–moderate disease, and for more severe patients wishing to delay TKR surgery,is recommended by the ESCEO taskforce. Further investigation into the OA patient types most likely to benefit from IA HA is warranted. Viscosupplementation with IA HA is a safe and effective component of the multi-modal management of knee OA. [less ▲]

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See detailElements of stochastic processes 2015--2016: course material
Arnst, Maarten ULg

Learning material (2016)

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See detailApport du cathétérisme cardiaque dans le diagnostic et le traitement de la maladie coronarienne avant 40 ans
MEURICE, Caroline; LEGRAND, Victor ULg; PIERARD, Luc ULg

in Revue Médicale de Liège (2016), 71(3), 129-136

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See detailTraces d'indices actanciels en néo-égyptien
Winand, Jean ULg

in Collombert, Philippe; Lefevre, Dominique; Polis, Stéphane (Eds.) et al Aere perennius. Mélanges égyptologiques en l’honneur de Pascal Vernus (2016)

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See detailThe alarming increase in antibiotic-resistant bacteria
Frère, Jean-Marie ULg; Rigali, Sébastien ULg

in Drug Target review (2016)

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See detailAby Warburg, Textes & Fragments (1926-1929) suivi de "Plasticité du visuel. Montages et usages critiques de l'image chez A. Warburg" (M. Hagelstein)
Hagelstein, Maud ULg; Letawe, Céline ULg

Book published by Presses Universitaires de Liège (2016)

Assorti d’une série de textes inédits, cet ouvrage monographique vise à faire connaître dans le milieu francophone les écrits d’Aby Warburg (1866-1929), en particulier ceux rédigés dans les dernières ... [more ▼]

Assorti d’une série de textes inédits, cet ouvrage monographique vise à faire connaître dans le milieu francophone les écrits d’Aby Warburg (1866-1929), en particulier ceux rédigés dans les dernières années de sa vie. Peu connus, ces textes datent de la période d’élaboration de l’Atlas d’images Mnemosyne – Atlas dont le succès grandissant auprès des artistes et des théoriciens de l’art n’est plus à démontrer . Mais si Mnemosyne attire de plus en plus les spécialistes des images de tous horizons, on accorde encore peu d’intérêt aux textes et aux notes rédigées par son auteur dans les années 1926-1929. Ces textes auraient du accompagner les planches de l’Atlas si le projet avait abouti. Or, les manuscrits inédits conservés au Warburg Institute (Londres) montrent la portée philosophique des recherches tardives d’Aby Warburg. Il y développe une théorie culturelle de l’image pour le moins originale et qui a profondément influencé certaines démarches plus contemporaines (dans les domaines de l’histoire de l’art, de l’anthropologie du visuel, de la Bildwissenschaft allemande ou des Visual Studies anglo-saxonnes). À l’occasion d’un débat avec les pensées de Nietzsche et de Burckhardt, Warburg élabore une conception nouvelle de la Kultur. [less ▲]

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See detailDesign of joints i steel and composite structures
Jaspart, Jean-Pierre ULg; Weynand, Klaus

Book published by Ernst & Sohn, a Wiley brand (2016)

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See detailThe Strasbourg Manuscript : A Mediaeval Tradition of Artists’ Recipe Collections (1400-1570)
Neven, Sylvie ULg

Book published by Archetype Publication (2016)

The ‘Strasbourg Manuscript’ is a well-known example of artistic literature, presented in the form of a collection of recipes. Tis manuscript, whose content has been dated to the beginning of the 15th ... [more ▼]

The ‘Strasbourg Manuscript’ is a well-known example of artistic literature, presented in the form of a collection of recipes. Tis manuscript, whose content has been dated to the beginning of the 15th century, was believed to be the oldest German-language source for the study of Northern European painting techniques . The art technological instructions of the Strasbourg Manuscript cover a wide range of crafts. Its recipes are mostly dedicated to painting and illumination and, in particular, to the preparation of pigments including re ning, grinding, suitable mixtures, the building up of layers of paint, and the use of gold in gilding and its imitation. Some recipes concern the manufacture of speci c binding agents, glues and varnishes used on various artistic supports. Others correspond to instructions for auxiliary crafts such as polychromy and mural painting, the dyeing of textiles and skins, the preparation and colouring of the parchment support etc. In the 19th century, a copy of the Strasbourg Manuscript was made for Sir Charles Eastlake, the first director of the National Gallery, London, and was partly published in 1847. The original manuscript was later destroyed during the 1870 re in the Strasbourg Library – the text of the original recipe collection was therefore preserved only in the form of Eastlake’s copy. Nevertheless, as with a large number of recipe collections produced in the Middle Ages, the Strasbourg Manuscript was the subject of copying and compilation processes. Its content thus survives not only in other contemporary manuals, but also in later treatises. Variants of its text were written in the south of Germany between 1400 and 1570. This volume is the rst comprehensive study of the Strasbourg Manuscript and its relationship with other surviving artisanal recipe collections. [less ▲]

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See detailLes ambiguïtés de l’anthropomorphisme : de la divinité agissante à sa statue dans la céramique grecque
Collard, Hélène ULg

in MethIS : Méthodes et Interdisciplinarité en Sciences Humaines (2016), 5

L’image, sous ses divers aspects, a joué un rôle essentiel dans la vie des anciens Grecs, en particulier dans le domaine religieux, puisque elle était l’une des modalités de perception du divin. En Grèce ... [more ▼]

L’image, sous ses divers aspects, a joué un rôle essentiel dans la vie des anciens Grecs, en particulier dans le domaine religieux, puisque elle était l’une des modalités de perception du divin. En Grèce, la figuration anthropomorphe des dieux est largement majoritaire. Toutefois, en se tournant vers un support particulier, le vase peint, et un type de représentation particulier, la statue divine, on montrera ici que l’anthropomorphisme a pu amener une certaine ambiguïté. Dans la céramique, les représentations de statues fonctionnent sur plusieurs modes, selon la chronologie. C’est ce que l’on propose d’analyser, en examinant un groupe de vases décorés d’un thème semblable et sur lesquels une divinité est représentée, mais soit sous la forme d’une figure « vivante », soit d’une statue plus ou moins bien caractérisée. Cette étude permettra d’aborder les concepts de « fixité » et de « mouvement » de/dans l’image, mais aussi d’explorer quelques pistes de réflexions sur l’image divine et, plus largement, sur les modes de représentation du divin en Grèce ancienne. [less ▲]

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See detailArthrose
Kaux, Jean-François ULg

Learning material (2016)

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See detailCitizen Science in Vlaanderen: U telt mee?!
Hens, Niel; Huyse, Tine; Samaey, Giovanni et al

Article for general public (2016)

This position paper seeks to raise further awareness of the topic of Citizen Science (CS) amongst researchers and broader publics in Flanders. The memorandum clarifies the concept of CS and situates it ... [more ▼]

This position paper seeks to raise further awareness of the topic of Citizen Science (CS) amongst researchers and broader publics in Flanders. The memorandum clarifies the concept of CS and situates it within its historical and contemporary contexts. It also reflects on the potential for involving the broader community in science, while providing examples of situations and areas in which involvement of this kind is already taking place in Flanders. Based on a survey that questioned Flemish researchers on CS, the memorandum contains four recommendations for the governing bodies of universities, academic stakeholders and scientists and scholars specifically. Finally, this position paper offers a series of tips and tricks, along with testimonies for researches who would like to start working in the CS field. [less ▲]

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See detailIntroduction : Le double mouvement de l’adaptation
Englebert, Jérôme ULg; Follet, Valérie

in Englebert, Jérôme; Follet, Valérie (Eds.) Adaptation : Essai collectif à partir des paradigmes éthologiques et évolutionnistes (2016)

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See detailConclusion : Anormalité ou anomalie ?
Englebert, Jérôme ULg; Follet, Valérie

in Englebert, Jérôme; Follet, Valérie (Eds.) Adaptation : Essai collectif à partir des paradigmes éthologiques et évolutionnistes (2016)

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See detailJohn Price, « Territory, rank and mental health: The history of an idea »
Englebert, Jérôme ULg; Follet, Valérie

in Englebert, Jérôme; Follet, Valérie (Eds.) Adaptation : Essai collectif à partir des paradigmes éthologiques et évolutionnistes (2016)

Detailed reference viewed: 29 (0 ULg)