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See detailIntracellular concentration of cryoprotectant during vitrification and slow-freezing cryopreservation procedures
Vanderzwalmen, Pierre ULg; Ectors, Fabien ULg; Wirleitner, Barbara et al

in Tucker, Mickael; Lieberman, Juergen (Eds.) Vitrification in assisted reproduction: second edition (2015)

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See detailSommeil & vieillissement
Vandewalle, Gilles ULg

Conference given outside the academic context (2015)

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See detailCurrent trend in carbon tetrachloride from several NDACC FTIR stations
Hannigan, J.; Palm, M.; Conway, S. et al

Conference (2015, October 05)

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See detailCHANGEMENT CLIMATIQUE: Manger - Bouger
Ozer, Pierre ULg

Conference given outside the academic context (2015)

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See detailEpistasis associated to inflammatory bowel disease (IBD) in humans
Gusareva, Elena ULg; Wei, Zhi; Traherne, J.A. et al

Poster (2015, October 05)

Gene-gene interactions underlie biochemical pathways and have been well demonstrated in model organisms. Very few examples exist on replicated epistasis in humans. Here, we performed genome-wide scans to ... [more ▼]

Gene-gene interactions underlie biochemical pathways and have been well demonstrated in model organisms. Very few examples exist on replicated epistasis in humans. Here, we performed genome-wide scans to detect epistasis associated to Crohn’s disease (CD) and ulcerative colitis (UC). We used extensive data of the IIBDGC consisting of 18277 and 14224 CD and UC patients, respectively, and ~34050 healthy controls from 15 European countries typed on the Immunochip. At first, we removed rare variants at MAF<0.05 and filtered common variants at linkage disequilibrium (LD) of r2>0.75. To limit our results to independent effects, SNPs on chromosome 6 (which contains the HLA locus), were furthermore pruned to ensure an LD of r2<0.35. We adjusted the binary traits, CD and UC, for population stratification by regressing out the first 5 principal components in R-3.0.1. The study cohorts were randomly stratified into two subgroups (referred as discovery and replication). We then performed screenings for epistatic interactions with new adjusted trait values in the two subgroups using multidimensional reduction tool MB-MDR with permutation-based (step-down MaxT) multiple testing correction and significance assessment at 0.05. We identified 14 and 6 SNP-pairs associated to CD and UC, respectively, which were concordant between the discovery and replication groups. All SNP-pairs involved concomitant variants located on the same chromosomes (for CD at 1p31.3, 5p13.1, 16q12.1 and for UC at 1p31.3, 6p21.3). A more detailed investigation of these findings, as well as the implementation of different analysis protocols, will further increase our understanding of possible epistatic mechanisms underpinning IBD. [less ▲]

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See detailDe l'application des mathématiques en biologie : acquis et perspectives
Brostaux, Yves ULg

Conference (2015, October 03)

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See detailLeucocytes and lipid particles filtration in suction blood during cardiopulmonary bypass: impact on kidney function evaluated with a monocentric prospective randomized study.
LAGNY, Marc-Gilbert ULg; KOCH, Jean-Noël ULg; BLAFFART, Francine ULg et al

Conference (2015, October 03)

OBJECTIVE: Cardiac surgery may be complicated by acute kidney injury (AKI). Cardiotomy suction during cardiopulmonary bypass (CPB) is deleterious. A few studies have demonstrated that shed mediastinal ... [more ▼]

OBJECTIVE: Cardiac surgery may be complicated by acute kidney injury (AKI). Cardiotomy suction during cardiopulmonary bypass (CPB) is deleterious. A few studies have demonstrated that shed mediastinal blood (SMB) suction during cardiopulmonary bypass (CPB) can increase inflammatory response and lipids emboli. These 2 factors contribute to the development of postoperative AKI. The RemoweLL (RemoweLeucoLipids, Eurosets™, Italy) filter is a recent designed cardiotomy with a multilayer filter for activated leucocytes filtration and a syphon for lipid particles sequestration. The SMB can be collected and filtered in this supplementary cardiotomy added to CPB circuit. The aim of this monocentric prospective study was to compare the specific RemoweLL cardiotomy filtration for suction blood during CPB and a conventional 40 µm filter (Admiral, Eurosets™, Italy). The primary goal was to evaluate the AKI within 48 hours after surgery using the Acute Kidney Injury Network classification (AKIN classification) but also measuring early specific biomarkers of AKI: serum Cystatine C and urinary neutrophil gelatinase-associated lipocalin (NGAL). METHODS: Sixty patients scheduled for elective cardiac surgery (aortic or mitral valvular combined or not with coronary bypass grafting) with a glomerular filtration rate (GFR) > 45mL/min. were randomly into 2 groups for SMB filtration: - Groupe 1 (n=30) with RemoweLL cardiotomy (Leucocytes and lipids filter); - Groupe 2 (n=30) with Admiral cardiotomy (conventional 40 µm filter). All components: venous reservoir, oxygenator and surface treatment were similar in both groups. [less ▲]

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See detailPour une vision intégrée du prévenir et du guérir
Vanmeerbeek, Marc ULg

Scientific conference (2015, October 02)

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See detailPréface
Marganne, Marie-Hélène ULg

in de Haro Sanchez, Magali (Ed.) Ecrire la magie dans l'antiquité. Actes du colloque international (Liège, 13-15 octobre 2011) (2015)

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See detailBaccio Bandinelli théoricien. Réflexions sur le "Libro del Disegno"
Marique, Charlotte ULg

Conference (2015, October 02)

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See detailNeurosciences et Psychiatrie : parallélisme ou convergence ?
Desseilles, Martin ULg

Scientific conference (2015, October 02)

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See detailNovel chitosan hydrogel for the treatment of osteoarthritis.
Henrotin, Yves ULg

Conference (2015, October 02)

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See detailConclusions
Valenti, Gianluca ULg; Miesse, Hélène ULg

Conference (2015, October 02)

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See detailPhénoménologie de l’électrochoc : Une reprise du cas Jonas
Englebert, Jérôme ULg; Cormann, Grégory ULg

Scientific conference (2015, October 02)

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See detailSpectral Variations of Of?p Oblique Magnetic Rotator Candidates in the Magellanic Clouds
Walborn, Nolan R.; Morrell, Nidia I.; Nazé, Yaël ULg et al

in Astronomical Journal (The) (2015), 150

Optical spectroscopic monitoring has been conducted of two O stars in the SMC and one in the LMC, the spectral characteristics of which place them in the Of?p category, which has been established in the ... [more ▼]

Optical spectroscopic monitoring has been conducted of two O stars in the SMC and one in the LMC, the spectral characteristics of which place them in the Of?p category, which has been established in the Galaxy to consist of oblique magnetic rotators. All of these Magellanic stars show systematic spectral variations typical of the Of?p class, further strengthening their magnetic candidacy to the point of virtual certainty. The spectral variations are related to photometric variations derived from Optical Gravitational Lensing Experiment data by Nazé et al. in a parallel study, which yields rotational periods for two of them. Now circular spectropolarimetry is required to measure their fields, and ultraviolet spectroscopy to further characterize their low-metallicity, magnetically confined winds, in support of hydrodynamical analyses. [less ▲]

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