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See detailStudies of the Domains II and III of Bacillus subtilis PBP4a in relation with the protein localization
Vanden Broeck, Arnaud ULg; Van Der Heiden, Edwige ULg; Sauvage, Eric ULg et al

Poster (2014, April 23)

Bacillus subtilis PBP4a belongs to the class-C1 PBPs characterized by two internal additional domains of unknown function. Seven lysine residues (K) are protruding from domain II. Four of them have been ... [more ▼]

Bacillus subtilis PBP4a belongs to the class-C1 PBPs characterized by two internal additional domains of unknown function. Seven lysine residues (K) are protruding from domain II. Four of them have been mutated in glutamine residues (Q). Both proteins (WT and Mut4KQ PBP4a) have been produced without signal peptide in E. coli and their sub-cellular localizations determined by measuring the DD-carboxypeptidase activities in the different compartments (cytoplasmic vs membrane attached proteins). In order to detect a possible influence of the PBP4a domain III in the localization of the protein, its encoding sequence has been cloned into pET-28b-BlaP, a vector allowing the production of WT BlaP β-lactamase or BlaP/DIII chimeric protein (with domain III inserted in a permissive loop of BlaP). The nitrocefin hydrolysis activities of BlaP or BlaP/DIII have been measured in the different cellular compartments. [less ▲]

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See detailThe archeological context of the last Neandertals and first Modern Humans in Europe
Flas, Damien ULg

Scientific conference (2014, April 23)

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See detailL'approche par compétences dans le cours de droit matériel européen
Sibony, Anne-Lise ULg

Diverse speeche and writing (2014)

Cette vidéo expose un exemple de mise ne oeuvre de l'approche par compétences dans le cadre d'un cours de droit européen (cours de 3ème année donné à 200 étudiants) et des séances d'exercices ... [more ▼]

Cette vidéo expose un exemple de mise ne oeuvre de l'approche par compétences dans le cadre d'un cours de droit européen (cours de 3ème année donné à 200 étudiants) et des séances d'exercices correspondantes. Elle est accompagnée d'un document qui illustre le propos par des exemples concrets (conseils donnés aux étudiants, corrigé d'exercice, grille d'évaluation). [less ▲]

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Peer Reviewed
See detailLe psychopathe : apprésentation, chosification de l’alter ego et compétences émotionnelles
Englebert, Jérôme ULg

Conference (2014, April 23)

La psychopathie est une entité diagnostique « trouble », tant au sein de la tradition psychopathologique que dans les nosographies internationales contemporaines (DSM-IV et DSM-V). Le modèle faisant ... [more ▼]

La psychopathie est une entité diagnostique « trouble », tant au sein de la tradition psychopathologique que dans les nosographies internationales contemporaines (DSM-IV et DSM-V). Le modèle faisant autorité en psychologie forensic est celui développé par R.D. Hare (2003) à travers une échelle diagnostique appelée PCL-R. Ce modèle rencontre, d’un point de vue théorique, plusieurs apories, et, d’un point de vue clinique, de nombreuses impasses. Nous proposons de réaliser un exercice de compréhension psychopathologique axé sur notre pratique clinique en nous inspirant des recommandations du courant de la psychopathologie phénoménologique (Minkowski, 1966 ; Binswanger, 1960 ; Stanghellini, 2006 ; Sass, Parnas & Zahavi, 2011). Celui-ci suggère de procéder par la mise en évidence de la structure psychopathologique qui organise le fonctionnement psychologique du sujet. De façon plus précise, nous centrerons notre propos sur deux dimensions essentielles à l’être-au-monde psychopathique. D’une part, nous réaliserons une comparaison avec l’être-au-monde maniaque à travers les variables de l’apprésentation et de la chosification de l’alter ego – telles que les développe Binswanger (1960). Nous discuterons, d’autre part, du vécu émotionnel propre à la psychopathie qui est davantage source d’adaptation (du moins en certaines situations) que de carence véritable. Ce constat nous permettra de rediscuter brièvement de la notion d’empathie en psychopathologie. Nous verrons que ces dimensions propres à l’existence psychopathique font apparaitre une thématique explicitement absente de la nosographie de Hare, celle de la morale. [less ▲]

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See detailSpatio-Temporal Analysis of Equatorial Ionospheric Scintillations in the Frame of Absolute GNSS Positioning Algorithms
Lonchay, Matthieu ULg; Cornet, Yves ULg; Aquino, Marcio et al

Poster (2014, April 23)

The ionosphere has always been a major limitation for GNSS positioning applications. Free electrons in the ionosphere perturb the propagation of GNSS radio signals involving both refraction and ... [more ▼]

The ionosphere has always been a major limitation for GNSS positioning applications. Free electrons in the ionosphere perturb the propagation of GNSS radio signals involving both refraction and diffraction effects. The ionospheric refraction mainly results in a modification of the propagation speed of the GNSS electromagnetic signals, inducing an error (propagation delay or phase advance depending on the observable) in GNSS measurements. In the frame of absolute positioning techniques, single-frequency algorithms usually exploit an ionospheric model to mitigate the ionospheric error while dual-frequency algorithms, such as the well-known Precise Point Positioning (PPP), take the benefit of the availability of two frequencies and the fact that the ionosphere is a dispersive medium to construct an ionosphere-free mathematical model. But these two strategies are not able to counteract the effect of the ionospheric diffraction which is due to small-scale irregularities in the free electron density. By scattering GNSS signals, these irregularities generate rapid fluctuations (scintillations) in the amplitude and phase of GNSS signals with critical consequences for GNSS applications: cycle slips, signal power fading, receiver loss of lock and poor resulting satellite geometry. The goal of our research is to develop a strategy to mitigate the effect of ionospheric scintillations on absolute GNSS positioning techniques, in particular the SPP (Standard Point Positioning) and the PPP (Precise Point Positioning). The strategy is based on the adjustment of the stochastic model. In order to construct the stochastic model (diagonal and non-diagonal elements) and study the correlation between observables, we adopted a “spatial” and an “empirical” approach. The spatial approach consists in a study of the spatial autocorrelation existing in scintillations effects on GNSS signals. The spatial autocorrelation is detected by using specific spatial analysis techniques applied on data from a network of ISMR (Ionospheric Scintillation Monitoring Receiver) stations located at equatorial and polar latitudes, where scintillations effects are most severe. The knowledge of how scintillation effects are spatially correlated is helpful for determining a coherent stochastic model. The empirical approach does not take into account the phenomenon spatiality and the locations of the measurements but only the observation data. Its objective is to determine the statistical correlation which exists between GNSS measurements during a scintillation event by using a moving filter applied on GNSS observation and scintillation data. The spatial approach exploits data and data locations while the empirical approach is based only the data itself. [less ▲]

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See detailDavid Knoke, Economic networks
Dufays, Frédéric ULg

in Lectures (2014)

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See detailLes institutions bleges à l'aube des élections du 25 mai 2014
Grandjean, Geoffrey ULg

Conference given outside the academic context (2014)

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Peer Reviewed
See detailElaboration of drug nanocarriers based on a glucosamine labeled amphiphilic polymer
Boyère, Cédric; Duhem, N; Debuigne, Antoine ULg et al

in Polymer Chemistry (2014), 5(8), 3030-3037

A new functional polymer micelle with high loading efficiency of a poorly soluble drug was made of biocompatible and/or biosourced compounds, i.e. cholesterol-poly(ethylene glycol)-glucosamine (Chol-PEG ... [more ▼]

A new functional polymer micelle with high loading efficiency of a poorly soluble drug was made of biocompatible and/or biosourced compounds, i.e. cholesterol-poly(ethylene glycol)-glucosamine (Chol-PEG-GlcNH2). A synthesis strategy combining enzymatic and metal-free click chemistry was developed in order to meet the increasingly stringent requirements of biomedical applications. After the self-assembly of the Chol-PEG-GlcNH2 amphiphilic polymer in water, the presence of glucosamine at the micelle surface confers an active targeting moiety to the nanocarriers whereas protonation of the peripheral primary amine delay their aggregation. The complete characterization of this novel functional amphiphilic bioconjugate is presented as well as its aqueous solution behaviour and encapsulation efficiency using ketoconazole as a model hydrophobic drug. [less ▲]

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See detailDual Mode of Action of Amylolysin, a Type-B Lantibiotic Produced by Bacillus amyloliquefaciens GA1
Arguelles Arias, Anthony ULg; Joris, Bernard ULg; Fickers, Patrick

in Protein & Peptide Letters (2014), 4

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See detail(Co)Polymerization of vinyl levulinate by cobalt-mediated radical polymerization and functionalization by ketoxime click chemistry
Allaoua, Imène; Eleuterio, Beatriz; Obadia, Mona M. et al

in Polymer Chemistry (2014), 5(8), 2973-2979

Vinyl levulinate is synthesized from levulinic acid by palladium-catalyzed vinyl exchange and is characterized by NMR and ESI-HRMS techniques. Homopolymerization of vinyl levulinate and random ... [more ▼]

Vinyl levulinate is synthesized from levulinic acid by palladium-catalyzed vinyl exchange and is characterized by NMR and ESI-HRMS techniques. Homopolymerization of vinyl levulinate and random copolymerization with vinyl acetate by cobalt-mediated radical polymerization affords well-defined ketone functionalized poly(vinyl ester)s. The impact of temperature, solvent and theoretical degree of polymerization on monomer conversion and control of the polymerization is studied by 1H NMR and size exclusion chromatography techniques. The ketoxime conjugation of O-benzylhydroxylamine with the pendant ketone functionality of poly(vinyl levulinate-co-vinyl acetate) is demonstrated. [less ▲]

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See detailLa Belgique, un pays complexe
Hermans, Michel ULg

in Perdigon, Marie-France (Ed.) Actes des VIIème entretiens sur l'identité européenne (2014, April 19)

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See detailParticipation au Jury du Festival philosophique du Film "Eidolon" (concours "lycéens" et "pro")
Herla, Anne ULg

Diverse speeche and writing (2014)

Detailed reference viewed: 12 (0 ULg)