Last 7 days
Bookmark and Share    
See detailGérer le changement: une dynamique multidimensionnelle et participative
Lisein, Olivier ULg

Scientific conference (2017, May)

Detailed reference viewed: 42 (2 ULg)
Full Text
Peer Reviewed
See detailA surprising and dramatic neuroendocrine-immune phenotype of mice deficient in Growth Hormone-Releasing Hormone (GHRH)
Farhat, Khalil ULg; Bodart, Gwennaëlle ULg; Renard, chantal et al

Poster (2017, May)

In the framework of close interactions between the immune and neuroendocrine systems, Growth Hormone (GH) has been proposed to exert significant effects on the immune system, but there is not yet a ... [more ▼]

In the framework of close interactions between the immune and neuroendocrine systems, Growth Hormone (GH) has been proposed to exert significant effects on the immune system, but there is not yet a consensus about GH immunomodulatory properties. These studies investigated the immune and anti-infectious response of dwarf Ghrh-/- mice presenting a severe deficiency of the GHRH/GH/IGF-1 axis. In basal conditions, thymic parameters and T-cell responses of Ghrh-/- mice were not severely affected but a constant B-cell lymphopaenia was observed. Thus, we investigated vaccine and anti-infectious responses of Ghrh-/- mice toward Streptococcus pneumonia, a B-dependent pathogen, Ghrh-/- mice were unable to trigger production of specific IgM and IgG against serotype 1 pneumococcal polysaccharide (PPS) after vaccination with either native PPS (Pnx23) or protein-PPS conjugate (Prev-13) vaccines. These vaccines both include the serotype 1 (our S.pneumoniae strain) and provide an effective protection in mice. A short GH supplementation to Ghrh-/- mice (1 daily injection of 1 mg/kg GH for 4 weeks) restored IgM and IgG response to Pnx23 vaccine but not to Prev-13. This suggests that GH could exert distinct impacts upon spenic areas. Furthermore, after intranasal instillation of a non-lethal dose (defined by the full clearance by WT C57BL/6 mice after 24h) of serotype 1 S.pneumoniae, Ghrh-/- mice exhibited a dramatic susceptibility. This was proved by a marked time-dependent increase in pulmonary bacterial, a septicemia already 24h after infection and a survival limit of 72h. We also observed a dramatic decrease in lung B- and T-cell populations and an increase in proportion of inflammatory macrophages. By contrast, wild-type and heterozygote mice completely cleared S.pneumoniae infection after 24h. In conclusion, our data show without ambiguity that the somatotrope GHRH/GH/IGF-1 axis plays an important and unsuspected role in defense against S.Pneumoniae. [less ▲]

Detailed reference viewed: 25 (3 ULg)
Peer Reviewed
See detailWork environment and work-to-family conflict: Mediating role of work investment.
Babic, Audrey ULg; Stinglhamber, Florence; Barbier, Marie ULg et al

Conference (2017, May)

Detailed reference viewed: 21 (4 ULg)
Peer Reviewed
See detailEffect of changing size and composition of a crop model ensemble on impact and adaptation response surfaces
A., Rodríguez; R., Ferrise; M., Ruiz-Ramos et al

in Book of Abstracts - MACSUR2017 Scientific Conference (2017, May)

Detailed reference viewed: 3 (1 ULg)
Peer Reviewed
See detailProbabilistic assessment of adaptation options from an ensemble of crop models: a case study in the Mediterranean"
R., Ferrise; M., Ruiz-Ramos; A., Rodríguez et al

in Book of Abstracts - MACSUR2017 Scientific Conference (2017, May)

Detailed reference viewed: 10 (1 ULg)
Full Text
Peer Reviewed
See detailTesting a general approach to assess the degree of disturbance in tropical forests
Sellan, Giacomo; Simini, Filippo; Maritan, Amos et al

in Journal of Vegetation Science (2017), 28(3), 459668

Questions: Is there any theoretical model enabling predictions of the optimal tree size distribution in tropical communities? Can we use such a theoretical framework for quantifying the degree of ... [more ▼]

Questions: Is there any theoretical model enabling predictions of the optimal tree size distribution in tropical communities? Can we use such a theoretical framework for quantifying the degree of disturbance? Location: Reserve of Yangambi, northeast region of the Democratic Republic of Congo. Methods: We applied an allometricmodel based on the assumption that a vir- tually undisturbed forest uses all available resources. In this condition, the forest structure (e.g. the tree size distribution) is theoretically predictable fromthe scal- ing of the tree crown with tree height at an individual level. The degree of dis- turbance can be assessed through comparing the slopes of the tree size distribution curves in the observed and predicted conditions. We tested this tool in forest stands subjected to different degrees of disturbance. We inventoried trees >1.3 m in height by measuring the DBH in three plots of 1 ha each, and measured tree height, crownradius and crownlength in a sub-sample of trees. Results: All tree species, independently of the site, shared the same exponents of allometric relationships: tree height vs tree diameter, crown radius vs tree height, crown length vs tree height and consequently crown volume vs tree height, suggesting that similar trajectories of biomass allocation have evolved irrespective of species. The observed tree size distributions appeared to be power laws (excluding the finite size effect) and, as predicted, the slope was steeper in the less disturbed forest (?2.34) compared to the most disturbed (?1.99). The difference in the slope compared to the theoretical fully functional forest (?2.65) represents the metric for assessing the degree of disturbance. Conclusions: We developed a simple tool for operationalizing the concept of ‘disturbance’ in tropical forests. This approach is species-independent, needs minimal theoretical assumptions, the measurement of only a few structural traits and requires a low investment in equipment, time and computer skills. Its simple implementation opens new perspectives for effectively addressing initiatives of forest protection and/or restoration. [less ▲]

Detailed reference viewed: 36 (11 ULg)
Full Text
Peer Reviewed
See detailIsokinetic profil of subjects with proximal patellar tendinopathy
Croisier, Jean-Louis ULg; Roberjot, Mathieu; DELVAUX, François ULg et al

in The Future of Football Medicine (2017, May)

Introduction: Proximal patellar tendinopathy is relatively common among sportsmen, even among football players who do repetitive shooting sessions. However, the strength profile of subjects with proximal ... [more ▼]

Introduction: Proximal patellar tendinopathy is relatively common among sportsmen, even among football players who do repetitive shooting sessions. However, the strength profile of subjects with proximal patellar tendinopathies is rarely described and the isokinetic profile remains unknown. Purpose: We aimed to determine the strength profile of subjects suffering from this frequently recurrent pathology. Methods: Forty-three players (29,1±8.5 y.o.; 78.1±11.9kg; 179.3±7.2cm) with chronic proximal patellar tendinopathy confirmed by ultrasounds were recruited. Quadriceps and hamstrings muscular performances of the healthy and pathological side were measured using an isokinetic dynamometer (Cybex Norm) at the concentric speed of 60°/s (C60) and 240°/s (C240) and at the eccentric speed of 30°/s (E30 - only for hamstrings). A visual analogic scale of pain (VAS) has also been used after each isokinetic test in order to associate the level of complaints and the intensity of contractions. Results: The results (Table 1) for the isokinetic tests comparing the healthy (HS) to the pathological side (PS) are significant for the different conditions of contraction and test speeds, as for the results of the VAS associated to those tests (p<0.01). Indeed, pathological limbs had a maximum peak torque for the quadriceps at C60 and at C240 lower than healthy limbs (2.17 ± 0.68 N.m/kg vs 2.47 ± 0.55 N.m/kg, p = 0.0003 and 1.46 ± 0.42 N.m/kg vs. 1.56 ± 0.31 N.m/kg, p = 0.02, respectively); this represents a bilateral difference of 14% for C60 and 7% in C240. In E30, pathological limbs were also weaker than the healthy limbs (2.46 ± 0.91 N.m/kg vs 2.79 ± 0.96 N.m/kg, p = 0.0008) which represents a difference of 13% between healthy and pathological limbs. For the hamstrings of the pathological limbs, we observed a maximum peak torque at C60 and C240 lower than for the hamstrings of the healthy limbs (1.26 ± 0.37 N.m/kg vs. 1.37 ± 0.36 N.m/kg, p = 0.006 and 0.80 ± 0.23 N.m/kg vs 0.85 ± 0.20 N.m/kg, p = 0.04). The bilateral differences of hamstring strength were 8.7% in C60 and 6% in C240. The PS were more painful than the HS (VAS C60: 3.47 ± 2.65 vs 0.20 ± 1.05; p>0.01; VAS C240: 2.83 ± 2.47 vs. 0.68 ± 0.10; p>0.01; VAS E30: 5,26 ± 2.78 vs 0.58 ± 1.93; p>0.01). The difference of pain can be seen especially in eccentric mode. This observation suggest that isokinetic tests, beyond the measure of strength, could represent a pain provocation test, even with a possible pronostic value for the efficacy of treatment. Conclusions: In our study, the isokinetic results of patients with proximal patellar tendinopathy showed a significant difference in strength profile between the HS and the PS as well as VAS associated with each tests. However, the diversity of outcomes recorded in our population suggests that an individualized rehabilitation treatment is probably more relevant than a common protocol for the healing of this tendon pathology. Isokinetic tests can also represent a tool for assessment of treatment planning. Finally, it would seem that isokinetic tests in the eccentric mode on the quadriceps can be a pain assessment tool for the pathological tendon. [less ▲]

Detailed reference viewed: 44 (1 ULg)
Full Text
Peer Reviewed
See detailHow to manage a case of ischial tuberosity avulsion fracture?
Tyberghein, Maëlle; Kaux, Jean-François ULg; GODON, Bernard ULg et al

in The Future of Football Medicine (2017, May)

Introduction Apophyseal avulsion fractures of the pelvis are common among teenage football player. Usually, they are the result of a sudden forceful concentric or eccentric contraction of the muscle ... [more ▼]

Introduction Apophyseal avulsion fractures of the pelvis are common among teenage football player. Usually, they are the result of a sudden forceful concentric or eccentric contraction of the muscle attached to the apophysis. Indeed, before ossification, the apophyseal growth cartilage is the weakest point in the musculotendinous unit, making the apophysis vulnerable to injure. Athletes most commonly affected are soccer players when they tackle or shot powerful at goal and gymnasts during floor exercises which imposed sudden and excessive lengthening. Management of these fractures remains unclear. There are no guidelines between conservative and surgical approach even if most publications recommend a surgery if the diastasis exceeds 2cm and a conservative approach on the other hand. Case report A sixteen-year-old high-level player presented at the consultation with right ischial pain. Three months earlier, while he was sprinting, he had felt acute pain opposite the ischial tuberosity which compelled him to stop the training. He had already consulted another physician, who prescribed an X-ray which revealed an avulsion fracture of the ischial tuberosity with a maximal diastasis of 1.9 cm (Fig 1.a.). According to most publications (1,3), surgery is advisable from 2 cm of diastasis. 1.9 cm was within the range between a surgical and a conservative approach, and the conservative one was applied. An isokinetic assessment was planned. It highlighted hamstring strength imbalances with bilateral difference of 31% in concentric strength and 28% in eccentric strength in comparison with the healthy side. The mixed ratio of the hamstrings in eccentric mode at 30°/s to quadriceps in concentric mode at 240°/s was decreased to 0.8, while the lower limit in our clinical practice corresponded to 0.9. The patient was not allowed to resume competition and a rehabilitation by specific and progressive strengthening in both modes of contraction was initiated; in particular the eccentric training was initially submaximal and progressively intensified. Six weeks later, isokinetic assessment was repeated and showed significant improvement of right hamstring strength, particularly for eccentric contraction. The greatest improvement was the mixed Hecc/Qconc ratio wich had increased from 0.8 to 1.44. In regard to radiology, we observed no change since the previous X-Ray (Fig 1.b.). Intensified training on the field was allowed in order to resume competition. Less than one year after the injury, the patient restarted competition successfully with performance levels which were almost the same as before the injury. Discussion Many publications have discussed the surgical versus the conservative approach to treating ischiatic avulsion. Most of the published literature advocate the relevance of surgery when the diastasis exceeds 2 cm because widely displaced fractures may lead to chronic symptomatology if the treatment remains conservative. Different criteria, such as pain relief, ability to perform in sport, gross strength, activity score, X-Rays, are used by authors to demonstrate the recovery after treatment. No study accurately measured the hamstring strength before and after treatment. However, strength imbalance, especially as regards the H/Q mixed ratio, significantly increases the risk of sustaining hamstring injury in soccer player (2). For our patient, the rehabilitation enabled him to re-establish hamstring strength in six weeks with substantial improvement of eccentric assessment. The mixed Hecc/Qconc ratio increased from 0.8 to 1.44. This improvement significantly decreased the risk of recurrence of hamstring injury. Regarding X-Ray imagery, there was no evidence of healing. We advocate that radiological assessment should not be the main recovery criterion and that specific strengthening should be started even when avulsion persists on the X-Ray. Furthermore, hamstring strength should be measured accurately and objectively, e.g. by isokinetism, to be one of the main return to play criterion in association with clinical data. [less ▲]

Detailed reference viewed: 31 (1 ULg)
Full Text
Peer Reviewed
See detailImpact on athletic performance of an early return to play following an ACL rupture
Duval, Thomas; LEHANCE, Cédric ULg; DANIEL, Christophe ULg et al

in The Future of Football Medicine (2017, May)

Introduction and purpose: The rupture of the anterior cross ligament (ACL) is the most frequent knee injury incurred during participation in sports and especially in football. Typically, the injured ... [more ▼]

Introduction and purpose: The rupture of the anterior cross ligament (ACL) is the most frequent knee injury incurred during participation in sports and especially in football. Typically, the injured athlete must undergo a surgical reconstruction of the ligaments followed by a lengthy rehabilitation period. However, the timeline for return to competition after this operation remains a challenge. More than one third of the athletes are unable to go back to sport performing at the same level prior to the injury. Approximately 65% of patients who experience this injury are able to return to sport at the same level. The fear of undergoing a new accident remains a major hurdle with this sporting recovery and the persistence of functional deficits is the first cause of repetitive ligament injuries. A reathletization program guided by strength and conditioning coaches results in a greatly reduces the risk of recurring injury by approximately 66% Methods: Our study involved a randomized control test. Our sample included ten subjects, five in the experimental group and five in the control group. Beginning one month post-surgery, the first group participated in weekly reathletization session beginning one week post-operation, associated with rehabilitation in classical physiotherapy, over a period of six months. The second participated solely in standard physiotherapy. Both groups were subjected to an initial isokinetic test as a base measurement to track improvement. After six months, the subjects of the two groups were evaluated using the following tools: an isokinetic test, a questionnaire of KOOS and finally a Hop tests. Results: The analysis of the isokinetic test and the questionnaire of KOOS ( p= 0.30) enabled us to note differences between the two groups using quantified values; however, the results were significant. On the other hand, the analysis of the results obtained through the functional tests showed significant differences between the two groups, highlighting the increased performance and benefit for the group participating in weekly reathletization. The experimental group displayed results in the three jump tests which indicates a greater strength and recovery. For the single hop test and the triple hop, the result is p = 0.04, and for the cross over test, the result is p = 0.02. Conclusion: In our preliminary study, the quantified values for both groups indicated a greater improvement in the performances of the experimental group reathletization. Although during the statistical analysis and especially in the isokinetic test, few elements significantly evolved to see any for the questionnaire KOOS. The preliminary analysis warrants an experiment involving a larger subject pool be completed. A reathletisation program beginning one month after operation has been found to limit the nuisances and long period of inactivities (weight increase, losses of muscular force, decrease of aerobic performances) typically experienced by those who rupture the ACL. This program has been found to be especially effective when coupled with regular physiotherapy meetings. [less ▲]

Detailed reference viewed: 34 (1 ULg)
Full Text
See detailPRTEE et épicondylite
Janssen, Arnaud; Kaux, Jean-François ULg

in Kinésithérapie du Sport Information (2017), (2ème trimestre 2017), 4-7

Detailed reference viewed: 26 (3 ULg)
Full Text
See detailEcomorphology of the axial skeleton in Odontocetes and Mysticetes
Gillet, Amandine ULg; Parmentier, Eric ULg

Poster (2017, May)

Ecomorphology concerns the study of the relationships between functional design and the environmental constraints acting on organisms. It aims to understand how the morphological variations among species ... [more ▼]

Ecomorphology concerns the study of the relationships between functional design and the environmental constraints acting on organisms. It aims to understand how the morphological variations among species can be related to environmental factors and impact fitness. Having a large diversity both in their morphology and ecology, the cetacean taxa appears to be the ideal taxa to tackle the relationships between the locomotor system and way of life. Different studies have already showed that the number and shape of vertebrae in different cetaceans can reflect the stiffness of the body and consequently can impact their swimming mode. The aim of this study is to establish relationships between characteristics of the vertebral column of different cetaceans and their ecology. Meristic and morphometric data were collected on the vertebrae (centrum lengths, heights and widths, neural spine heights and transverse processes lengths) of species of odontocetes housed in different Natural History Museums in the world (AM-ULg, RBINS, MNHN, SMNS, NRM, Queensland, PEM, Iziko). Preliminary results show clear morphological variations between species at the level of the number and sizes of vertebrae. There is a clear relationship between body size and number of vertebrae except in Delphinidae. This family has an important higher vertebral count. These differences should be related to different swimming modes and reflect the different ecological behaviours of the studied cetaceans. [less ▲]

Detailed reference viewed: 35 (7 ULg)
Full Text
Peer Reviewed
See detailPlatelet-rich plasma versus hyaluronic acid to treat patellar tendinopathies
Kaux, Jean-François ULg; Roberjot, Mathieu; SAMSON, Antoine ULg

in The Future of Football Medicine (2017, May)

Introduction: The treatment of patellar tendinopathies could be difficult. This is the reason why new treatments have been developed, among which platelet rich plasma (PRP) injections. Some clinical ... [more ▼]

Introduction: The treatment of patellar tendinopathies could be difficult. This is the reason why new treatments have been developed, among which platelet rich plasma (PRP) injections. Some clinical series have previously evaluated the effect of PRP in the treatment of proximal patellar tendinopathies. Recent systematic review concluded that PRP could be recommend as a treatment in such indication (1). Recently, the viscoelastic properties of hyaluronic acid (HA) on liquid connective tissue have been proposed for the treatment of tendinopathies (2). Some fundamental studies show encouraging results on HA’s ability to promote tendon gliding and reduce adhesion as well as to improve tendon architectural organisation. Some observations also support its use in a clinical setting to improve pain and function. Purpose: We aimed to compare the effect of PRP injection versus two injections of HA after three months on patients who have a proximal patellar tendinopathy. Methods: Eleven leisure football players with proximal patellar tendinopathies being not relieved after minimum three months of physiotherapy treatments where included. Six of them (group 1: 29.5±9.9 y.o.; 78.9±12.8kg; 177.4±6;9cm) have received a leukocyte poor PRP injection (obtained using an aphaeresis machine) under US guidance. This technique of PRP collection enable to obtain reproducible pure PRP with the same chosen concentration of 850 000 platelets/microliter. The other five subjects (group 2: 29.3±8.1 y.o.; 77.1±10.6kg; 178.1±5.8cm) received two HA 2% (40mg/2mL) injections (2mL) at one week apart. All of them have benefited of standardized rehabilitation, 3 times a week. Concerning the evaluation of the pathology, algo-functional tests (visual analogic scale (VAS), pressure algometer, IKDC score, VISA-P score), isokinetics (Cybex Norm; concentric 60°/s (C60), concentric 240°/s (C240) and eccentric 30°/s(E30)) associated to VAS, along with the patellar tendon ultrasonography (US) have been realized over three times (pre-injection, after 6 weeks, after 3 months post-injections). Results: The results of VAS (p<0,01), algometric scores (p<0,01), IKDC scores (p<0,01) and VISA-P (p<0,01) show a considerable improvement in the two groups, but not for the US findings. For the group 1 (Table 1), isokinetic tests show significant results for the hamstrings in C60°/s with an improvement of maximum peak torque (p=0,01) for the pathological limb, a diminution (p>0,05) for the healthy limb and during the analysis of the bilateral difference (p=0,0002). For the group 2, the improvement of quadriceps maximum peak torque in C240°/s is significant (p>0,01) for the pathological knee after 6 weeks post-injections only. The VAS associated with isokinetic tests decreases significantly for all contraction modes after three months of study. Conclusions: Both PRP and HA can improve the symptoms of proximal patellar tendinopathy, even if the results are slightly better in the PRP group. [less ▲]

Detailed reference viewed: 80 (3 ULg)
Full Text
Peer Reviewed
See detailFinite element model reduction for space thermal analysis
Jacques, Lionel ULg; Béchet, Eric ULg; Kerschen, Gaëtan ULg

in Finite Elements in Analysis and Design (2017), 127

To alleviate the computational burden of the nite element method for thermal analyses involving conduction and radiation, this paper proposes an automatic conductive-radiative reduction process based on ... [more ▼]

To alleviate the computational burden of the nite element method for thermal analyses involving conduction and radiation, this paper proposes an automatic conductive-radiative reduction process based on the clustering of a detailed mesh coming from a structural model for instance. The proposed method leads to a signi cant reduction of the number of radiative exchange factors (REFs) to compute and size of the corresponding matrix. It further keeps accurate conduction information by introducing the concept of physically meaningful super nodes. The REFs between the super nodes are computed through Monte Carlo ray-tracing on the partitioned mesh, preserving the versatility of the method. The resulting conductive-radiative reduced model is solved using standard iterative techniques and the detailed mesh temperatures can be recovered from the super nodes temperatures for further thermo-mechanical analysis. The proposed method is applied to a structural component of the Meteosat Third Generation mission and is benchmarked against ESATAN-TMS, the standard thermal analysis software used in the European aerospace industry. [less ▲]

Detailed reference viewed: 57 (6 ULg)
Full Text
Peer Reviewed
See detailProcess intensification of the synthesis of glycerol carbonate under microwave irradiation or continuous-flow conditions
Estager, Julien; Pleck, Julie; Gerardy, Romaric ULg et al

Conference (2017, May)

Despite low crude oil prices and the increasing access to shale gas, the establishment of a biobased economy remains a worldwide priority. An integrated biobased economy would not only consider renewable ... [more ▼]

Despite low crude oil prices and the increasing access to shale gas, the establishment of a biobased economy remains a worldwide priority. An integrated biobased economy would not only consider renewable biobased resources to provide industrially relevant chemicals, but would also redefine chemical processing by using greener, safer and more selective process technologies. The last few decades have witnessed the emergence of promising alternative energy sources such as microwave irradiation and alternative process technology such as continuous-flow reactors. Even if biobased chemicals are still marginal on the marklet compared to petrochemicals, many biorefineries are now able to convert biomass into biobased chemical building blocks of good purity on large scales. Amongst these products, glycerol – a side product of the biodiesel industry – is a particularly appealing chemical platform thanks to its high functionality and its wide availability. Various high-value added chemicals can be obtained from glycerol, among which glycerol carbonate retained our attention. Glycerol carbonate is an attractive glycerol derivative that can be used in many applications ranging from low-VOC solvent to polymer synthesis. Many publications describe its synthesis using different catalysts or alternative activation methods such as microwave. Our research effort in process intensification for the industrial valorization of biomass led us to develop an intensified carbonation process of glycerol under microwave irradiation, affording an unprecedented reactivity with short reaction times and high selectivity towards glycerol carbonate. Based on this preliminary study, and using the microwave-to-flow paradigm, continuous-flow processes using mesofluidic reactors have been developed to obtain glycerol carbonate in good yield and high purity. [less ▲]

Detailed reference viewed: 107 (6 ULg)
Full Text
See detailGestion d’un cas de brûlure étendue suite à une chirurgie de convenance
Picavet, Pierre ULg; Jacobs, Morgane ULg; Noël, Stéphanie ULg et al

in Monde Vétérinaire (Le) (2017), 169

Detailed reference viewed: 10 (2 ULg)
Peer Reviewed
See detailL’hospitalisation sous contrainte : Urgences psychiatriques et mises en observation.
Schmits, Emilie ULg; Evrard, Maude; Valassopoulou, Eftychia et al

Poster (2017, May)

Detailed reference viewed: 22 (1 ULg)
Full Text
Peer Reviewed
See detailModeling the strain localization around an underground gallery with a hydro-mechanical double scale model; effect of anisotropy
van den Eijnden, AP; Bésuelle, Pierre; Collin, Frédéric ULg et al

in Computers and Geotechnics (2017), 85

Detailed reference viewed: 61 (3 ULg)