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See detailCritical evaluation of promising markers for sarcopenia
CAVALIER, Etienne ULg; GADISSEUR, Romy ULg; GEBOES, Séverine ULg et al

in Osteoporosis International (2015), 26(1), 25

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See detailTrabecular bone score (TBS) as a new complementary appproach for osteoporosis evaluation in clinical practice
Harvey, NC; Binkley, N; Brandi, ML et al

in Osteoporosis International (2015), 26(1), 7

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See detailPrevalence of frailty in nursing home residents according to various diagnostic tools
Buckinx, Fanny ULg; Reginster, Jean-Yves ULg; Dardenne, Nadia ULg et al

in Osteoporosis International (2015), 26(1), 290

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See detailGlucosamine and chondroitin salts in the management of osteoarthritis in Europe
Reginster, Jean-Yves ULg

in Osteoporosis International (2015), 26(1), 8

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See detailCan we identify patients to be treated in osteoarthritis?
Arden, NK; Richette, P; Cooper, C et al

in Osteoporosis International (2015), 26(1), 10

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See detailRecommendations for the registration of drugs to treat sarcopenia
Reginster, Jean-Yves ULg; Cooper, C; Rizzoli, R et al

in Osteoporosis International (2015), 26(1), 11

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See detailClinical components linked to sarcopenia: the sarcophage study
Beaudart, Charlotte ULg; Reginster, Jean-Yves ULg; Petermans, Jean ULg et al

in Osteoporosis International (2015), 26(1), 258

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See detailGrip fatigue resistance and self-perceived fatigue in relation with sarcopenia and quality of life
Beaudart, Charlotte ULg; Reginster, Jean-Yves ULg; Bautmans, I et al

in Osteoporosis International (2015), 26(1), 265

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See detailAnti-inflammatory agents to treat or prevent type 2 diabetes, metabolic syndrome and cardiovascular disease.
Esser, Nathalie ULg; Paquot, Nicolas ULg; Scheen, André ULg

in Expert opinion on investigational drugs (2015), 24(3), 283-307

Introduction: There is a growing body of evidence to suggest that chronic silent inflammation is a key feature in abdominal obesity, metabolic syndrome, type 2 diabetes (T2DM) and cardiovascular disease ... [more ▼]

Introduction: There is a growing body of evidence to suggest that chronic silent inflammation is a key feature in abdominal obesity, metabolic syndrome, type 2 diabetes (T2DM) and cardiovascular disease (CVD). These observations suggest that pharmacological strategies, which reduce inflammation, may be therapeutically useful in treating obesity, type 2 diabetes and associated CVD. Area covered: The article covers novel strategies, using either small molecules or monoclonal antibodies. These strategies include: approaches targeting IKK-b-NF-kB (salicylates, salsalate), TNF-alpha (etanercept, infliximab, adalimumab), IL-1beta (anakinra, canakinumab) and IL-6 (tocilizumab), AMP-activated protein kinase activators, sirtuin-1 activators, mammalian target of rapamycin inhibitors and C-C motif chemokine receptor 2 antagonists. Expert opinion: The available data supports the concept that targeting inflammation improves insulin sensitivity and beta-cell function; it also ameliorates glucose control in insulin-resistant patients with inflammatory rheumatoid diseases as well in patients with metabolic syndrome or T2DM. Although promising, the observed metabolic effects remain rather modest in most clinical trials. The potential use of combined anti-inflammatory agents targeting both insulin resistance and insulin secretion appears appealing but remains unexplored. Large-scale prospective clinical trials are underway to investigate the safety and efficacy of different anti-inflammatory drugs. Further evidence is needed to support the concept that targeting inflammation pathways may represent a valuable option to tackle the cardiometabolic complications of obesity. [less ▲]

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See detailHealth related quality of life in sarcopenia
Beaudart, Charlotte ULg; Reginster, Jean-Yves ULg; Slomian, Justine ULg et al

in Osteoporosis International (2015), 26(1), 266

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See detailPercentage of women achieving non-osteoporotic BMD T-scores at the lumbar spine (LS) and total hip (TH) during up to 8 years of Denosumab (Dmab) treatment
Ferrari, S; Libanati, C; Lin, CJF et al

in Osteoporosis International (2015), 26(1), 268

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See detailIs early aggressive feeding dangerous for extremely low birth weight infants?
Blecic, Anne-Sophie; Delbos, Marion; RIGO, Vincent ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2015), 17(1), 83

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See detailLe Journal d’Antoine Galland (1646-1715) : la période parisienne. Volume III (1712-1713)
Bauden, Frédéric ULg; Waller, Richard; Veymiers, Richard ULg et al

Book published by Peeters (2015)

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See detailZebrafish bone and general physiology are differently affected by hormones or changes in gravity.
Aceto, Jessica ULg; Nourizadeh-Lillabadi, Rasoul; Marée, Raphaël ULg et al

in PLoS ONE (2015), in press

Teleost fish such as zebrafish (Danio rerio) are increasingly used for physiological, genetic and developmental studies. Our understanding of the physiological consequences of altered gravity in an entire ... [more ▼]

Teleost fish such as zebrafish (Danio rerio) are increasingly used for physiological, genetic and developmental studies. Our understanding of the physiological consequences of altered gravity in an entire organism is still incomplete. We used altered gravity and drug treatment experiments to evaluate their effects specifically on bone formation and more generally on whole genome gene expression. By combining morphometric tools with an objective scoring system for the state of development for each element in the head skeleton and specific gene expression analysis, we confirmed and characterized in detail the decrease or increase of bone formation caused by a 5 day treatment (from 5dpf to 10 dpf) of, respectively parathyroid hormone (PTH) or vitamin D3 (VitD3). Microarray transcriptome analysis after 24 hours treatment reveals a general effect on physiology upon VitD3 treatment, while PTH causes more specifically developmental effects. Hypergravity (3g from 5dpf to 9 dpf) exposure results in a significantly larger head and a significant increase in bone formation for a subset of the cranial bones. Gene expression analysis after 24 hrs at 3g revealed differential expression of genes involved in the development and function of the skeletal, muscular, nervous, endocrine and cardiovascular systems. Finally, we propose a novel type of experimental approach, the "Reduced Gravity Paradigm", by keeping the developing larvae at 3g hypergravity for the first 5 days before returning them to 1g for one additional day. 5 days exposure to 3g during these early stages also caused increased bone formation, while gene expression analysis revealed a central network of regulatory genes (hes5, sox10, lgals3bp, egr1, edn1, fos, fosb, klf2, gadd45ba and socs3a) whose expression was consistently affected by the transition from hyper- to normal gravity. [less ▲]

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See detailDer Standesunterschied als Prüfstein. Zur Frauenfreundschaft zwischen Elisa von der Recke und Sophie Becker
Leyh, Valérie ULg

in Recherches Germaniques (2015), 45

L’amitié joue un rôle central dans la vie et l’oeuvre d’Elisa von der Recke (1754-1833), écrivaine issue de la noblesse courlandaise. A côté de ses nombreux contacts avec des personnalités masculines ... [more ▼]

L’amitié joue un rôle central dans la vie et l’oeuvre d’Elisa von der Recke (1754-1833), écrivaine issue de la noblesse courlandaise. A côté de ses nombreux contacts avec des personnalités masculines, elle entretenait en effet des amitiés profondes avec des femmes de son temps, en particulier avec Sophie Becker, aux origines bourgeoises. Sur la base des écrits littéraires de ces deux femmes, l’article étudie cette amitié exceptionnelle en la confrontant au culte de l’amitié caractéristique du XVIIIe siècle et en montrant dans quelle mesure la différence de rang social défie l’idéal égalitaire des Lumières. Dans l’amitié avec Sophie, cette différence sociale apparaît très clairement, mais en se positionnant comme intellectuelle des Lumières et en s’appropriant le discours de l’amitié, Elisa von der Recke l’ignore et la considère comme insignifiante. Sophie, au contraire, ne peut s’empêcher de s’en apercevoir et questionne les fondements économiques de l’égalité au sein de l’amitié. Sa pensée pragmatique l’incite en effet à confronter les modèles littéraires avec la réalité et, dès lors, à constater que l’inégalité sociale est loin d’avoir disparu. [less ▲]

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See detailFarmers' practices and willingness to adopt supplemental irrigation in Burkina Faso
Zongo, Bétéo ULg; Diarra, Abdoulaye; Barbier, Bruno et al

in International Journal of Food and Agricultural Economics (2015), 3(1), 101-117

This study analyzes farmers' practices and willingness to adopt supplemental irrigation on rainfed crops in the Sahelian and Sudano-Sahelian areas of Burkina Faso. A survey of 629 farmers revealed a ... [more ▼]

This study analyzes farmers' practices and willingness to adopt supplemental irrigation on rainfed crops in the Sahelian and Sudano-Sahelian areas of Burkina Faso. A survey of 629 farmers revealed a diversity of farming practices within and between two agro-climatic zones. Over 65% of farmers believe that supplemental irrigation is a good way to mitigate the adverse effects of dry spells on crop yields. Determining factors of farmers’ willingness to adopt supplemental irrigation were identified using a logistic model. Lack of information is the major obstacle to promoting this innovation. Farmers’ training and information dissemination are the best ways to increase the acceptance of this promising technology. [less ▲]

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See detailHow to use ICT to help students to gain in confidence and efficiency in an algorithmic and computer programming course ?
Colaux, Catherine ULg; Soyeurt, Hélène ULg

in INTED2015 Proceedings (2015)

Algorithmic and computer programming in the bachelor’s degree is a course that demands a large involvement of students in performing non-standard exercises. This practical aspect is incompatible with ... [more ▼]

Algorithmic and computer programming in the bachelor’s degree is a course that demands a large involvement of students in performing non-standard exercises. This practical aspect is incompatible with classical ex cathedra course. It is the reason why we implement a blended learning approach much more responsive to students in a bachelor class of Bio Engineering at the Gembloux Agro Bio Tech Faculty (University of Liege, Belgium). This course alternates theoretical classes, take-home lessons with the help of online pedagogical resources and video and debriefing sessions where students have the possibility to benefit from teacher’ support. In doing so, the students are better prepared for the examination. They also gain in confidence and motivation. The teacher no longer simply transmits the knowledge but assists the students in their reflection process and their mastering of programming tools [less ▲]

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