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See detailTowards the development of a dual mode fluorescence/SERS dopamine aptasensor
Dumont, Elodie ULiege; De Bleye, Charlotte ULiege; Cailletaud, Johan ULiege et al

Poster (2017, September 21)

This work was dedicated to the development of a dual mode fluorescence and surface-enhanced Raman scattering (SERS) dopamine aptasensor. The preparation of the aptasensor was first optimised. Thereafter ... [more ▼]

This work was dedicated to the development of a dual mode fluorescence and surface-enhanced Raman scattering (SERS) dopamine aptasensor. The preparation of the aptasensor was first optimised. Thereafter, calibration curves were realised by means of fluorescence quenching and SERS. Finally, the specificity of both methods was tested. [less ▲]

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See detailQuelques pistes pour relancer la foresterie sociale et la participation en Afrique centrale
Vermeulen, Cédric ULiege

Conference (2017, September 21)

Detailed reference viewed: 75 (30 ULiège)
See detailHealing effect of controlled anti-electromigration on conventional and high-Tc superconducting nanowires
Baumans, Xavier ULiege; Lombardo, Joseph ULiege; Brisbois, Jérémy ULiege et al

Conference (2017, September 21)

At the present time, electron beam lithography (EBL) is considered as the reference technique for nanoscale patterning. However, making nanostructures below the sub-10 nm scale is still challenging due to ... [more ▼]

At the present time, electron beam lithography (EBL) is considered as the reference technique for nanoscale patterning. However, making nanostructures below the sub-10 nm scale is still challenging due to broadening effects (forward electron scattering, backscattering, electrostatic charging…), and requires strong investment in terms of cost for state-of-the-art EBL systems. In this sense, alternative methods are continuously explored in order to make such nanofabrication easily reachable. A promising approach consists of inducing atomic diffusion by a large current density. This phenomenon, called electromigration (EM), and well known since the 60’s as a failure mechanism in metallic interconnections [1], still attracts interests from scientists and engineers for its great potential for fabrication of microstructures and for its reversibility character [2, 3]. In this work, we show that the combination of electromigration and anti-electromigration allows the precise tuning of superconducting properties of Al nanoconstrictions and we also observe the reversibility of electromigration failure for this material (see Fig. 1). The same process has been applied on Nb, leading to a more irreversible process, and La2 xCexCuO4. For the latter material, we show that selective migration of oxygen atoms and the consequent doping modification induces a transition from a superconducting state to an insulating state in a reversible way [4]. We also discussed the possibility to enhance the electromigration technique by replacing the complex feedback control by a technique of electropulsing. These researches have direct practical impact as a method to explore the dependence of the characteristic parameters on the exact oxygen content and pave the way for a reversible control of local properties of nanowires. [less ▲]

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See detailAgeism and dementia stigma among healthcare professionals
Schroyen, Sarah ULiege; Adam, Stéphane ULiege; Missotten, Pierre ULiege

Poster (2017, September 21)

Detailed reference viewed: 38 (2 ULiège)
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See detailFacultative paedomorphosis in pond-breeding newts
Denoël, Mathieu ULiege

Conference (2017, September 21)

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See detailEffect of solution treatment on the fracture mechanisms of AlSi10Mg parts produced by Selective Laser Melting
Delahaye, Jocelyn ULiege; Mertens, Anne ULiege; Dedry, Olivier ULiege et al

Poster (2017, September 21)

Al alloy AlSi10Mg processed by Selective Laser Melting (SLM) displays high hardness and tensile strength due to its very fine eutectic microstructure [1]. However, as-built material exhibits low ductility ... [more ▼]

Al alloy AlSi10Mg processed by Selective Laser Melting (SLM) displays high hardness and tensile strength due to its very fine eutectic microstructure [1]. However, as-built material exhibits low ductility which is detrimental for applications where a high resilience is needed. To overcome this issue, solution heat treatment can be applied to soften and ductilize the material [2]. The very fine eutectic microstructure then turns into a dispersion of coarse globular Si precipitates. The distribution of Si precipitates seems to play a role in the fracture mechanism in as-built as well as solutionized tempers, but this effect is not yet fully understood [1,3]. Moreover, the lack of quantitative data makes it difficult to link precisely the fracture mechanisms to specific microstructural features. This study aims at investigating the role of the Si phase in the rupture mechanism, for both as-built and solutionized samples. It will focus more particularly on the heterogeneity of the distribution of Si precipitates where cracks are more likely to occur. Al cells size, along with the volume fraction and distribution of Si precipitates have been quantified by SEM image analysis. Al lattice parameter and Si crystallite size have been determined by X-ray diffraction/Rietveld analysis. For the image analysis, two types of specific zones have been observed i.e. the core and boundary of melt pools and Al grains, at different locations for representativity. These quantitative data have been compared with typical features observed on the fractured surface of tensile specimen. 1. D.-K. Kim et al. J. Alloys Compd. 686 (2016) 281. 2. W. Li et al., Mat. Sci. & Eng. A. 663 (2016) 116, 3. N.T. Aboulkhair et al. Mat. Sci. & Eng. A. 667 (2016) 139. [less ▲]

Detailed reference viewed: 62 (3 ULiège)
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See detailMedia content for value and growth stocks
Lambert, Marie ULiege; Moreno Miranda, Nicolas ULiege

Scientific conference (2017, September 21)

This paper aims at providing new insights on the risk drivers underly- ing the value premium documented by Fama and French (1993). By using news stories supplied by Thomson Reuters, we seek to explain ... [more ▼]

This paper aims at providing new insights on the risk drivers underly- ing the value premium documented by Fama and French (1993). By using news stories supplied by Thomson Reuters, we seek to explain comove- ment in value and growth stock returns from common information factors embedded in news. We also distinguish between information coming from common news stories and idiosyncratic shocks concerning a smaller subset of firms. This framework allows us to answer three questions: 1) Is there a common risk factor in the news which explains the value anomaly? 2) Is idiosyncratic news information priced? and 3) Does the amount of media attention to an information prime over the polarity of this information? [less ▲]

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See detailPerformance-based fire design and the U.S. prescriptive guidelines: A comparative study
Elhami Khorasani, Negar; Fang, Chenyang; Gernay, Thomas ULiege

in Proceedings of the 39th IABSE Symposium (2017, September 21)

Current codes and standards for fire design of structures in the United States are mainly based on design at the component level using prescriptive approaches, while performance-based design for fire can ... [more ▼]

Current codes and standards for fire design of structures in the United States are mainly based on design at the component level using prescriptive approaches, while performance-based design for fire can be used to address the needs for designing modern buildings with cost-effective solutions. Previous research shows that, when system-level performance is considered, fire protection on secondary beam elements in composite steel-concrete floor systems is not necessary due to the development of a membrane action in the concrete slab during fire. This study compares the fire design of a 9-story office building using prescriptive and performance-based designs. The safety levels of the two designs are investigated and compared. It is shown that performance-based design can be used to achieve the required level of safety currently enforced in the U.S. prescriptive guidelines, while providing an opportunity for cost reduction in fire protection material. [less ▲]

Detailed reference viewed: 64 (2 ULiège)
Peer Reviewed
See detailContinuing education with MOOCs. The case of children’s literature in French-speaking world
Dozo, Björn-Olav ULiege; Van de Poël, Jean-François ULiege; Centi, Valérie et al

Conference (2017, September 21)

1. Introduction Continuing education poses a challenge to the university: the objective is to allow professionals on the job market to enhance their competences through curricula adapted to their needs ... [more ▼]

1. Introduction Continuing education poses a challenge to the university: the objective is to allow professionals on the job market to enhance their competences through curricula adapted to their needs, both in terms of schedule and contents as well as teaching approaches applied. In its MOOCs policy, the University of Liège has identified this priority axis precisely to meet this requirement of schedule, contents and teaching approach. Already taught at the ULg, children's literature offered a perfect option for its pilot project. Popular culture studies are already one of the specificities of the Arts faculty program, and the University thought important to allow for a wider access to this teaching, responding to a growing interest from the civil society. 2. Problem description / challenges Up to now, there were, in French-speaking Belgium, only very few training opportunities on children's literature, based on cutting-edge scientific research, aimed at future or already established teachers. Although children's literature is one of the subject areas taught in secondary schools in French-speaking Belgium, it is not compulsory in the curriculum of aspiring French teachers at higher education institutions (whether universities or hautes écoles). Teaching children's literature thus depends on the teacher's good will: hence the importance of finding a way to train teachers in a subject area they have to teach to secondary school students by putting forward a large-scale but cost controlled solution, open to anyone looking for this specific training, and offering a certificate with a professional value. It was also important for the university to propose an innovative teaching format distinct from the practices generally in force and especially adapted to the adult-learning in terms of pedagogical approach (Thorpe,Edwards,Hanson, 1993). 3. MOOC Format Choosing the MOOC format was an important challenge: on the production level, above all, given the relative inexperience of the teaching staff, supported by a team of instructional designers and a production staff with experience in the creation of online contents for the University's online education platform; but also on the reception level, given that the expected audience is not particularly in line with digital technologies: MOOCs on literature are not the most common ones, and bookish readers are not known to be new technology buffs. The MOOC offers a selection of topics related to the field of children's literature, each under the responsibility of one team member, generally supported by experts. The MOOC tackles two main genres, the novel and the album, presents the publishing market, elaborates on digital literature and explores fictions beyond the book; it includes videos, quizzes, integrative activities, and feedback through forums. Each chapter of our MOOC adopts a modular and autonomous approach. These two characteristics allow learners to follow the MOOC according to their own needs or simply their interests. 4. Initial success The first session, in early March 2017, was a success, with more than 10000 subscribers, quite above the average for MOOCs in French. This is, for many subscribers, their first MOOC experience. Moreover, the motivation and investment of the community is remarkable: the forums are very active, the learners an-swer to and help each other. The feedback is extremely positive, showing a general willingness to partici-pate in the construction of collective knowledge useful for everyone. The information collected from participants is also an early success indicator in terms of population target. 5. Shaping Up for the Future Given this initial success, and in order to enhance this in-depth continued training, the teaching staff is envisioning for next year to develop a summer school linked to the MOOC and implement a blended learning element to our MOOC. The participants would first have to follow the MOOC and complete the required activities, in order to be granted certification. Afterwards, a limited number of these participants (probably around fifty) will be selected based on applications to participate in person to a course that would expand on the introduction to the subject offered by the MOOC. This training would highly benefit from the exceptional resources that the city of Liège holds for children's literature: the Michel Defourny archive, holding more than 30000 pieces, is indeed a unique site in Europe which deserves a better valorization from the University. [less ▲]

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See detailDéfinition d’un outil d’aide à la décision spatiotemporel structurant et articulant les potentialités de développement agricole : cas du Niger
Andres, Ludovic ULiege

Doctoral thesis (2017)

The concern about food insecurity in rural populations needs to be rethought and adapted to the overall living conditions of households by shifting to a concentrated spatial scale and a long-term analysis ... [more ▼]

The concern about food insecurity in rural populations needs to be rethought and adapted to the overall living conditions of households by shifting to a concentrated spatial scale and a long-term analysis. This change will allow identifying territories on a finer scale than the national level in order to allocate development objectives and to link them to areas with high development potential. The finer level of analysis will also allow regrouping the actions carried out on a smaller scale in order to structure all the activities carried out on the targeted area and population. The general comment that the development and emergency aid has been focused in circumscribed areas and that the level of analysis is based on two scales, one "macro" (national, regional, departmental) and the other "micro" (village, community, household, individual and community) reinforces the need to create an intermediate level of analysis. The latter will serve to improve the structure other actions carried out at different levels and the articulation of the activities to be carried out and the targeted population. From a state of the art analysis of subject such as development, targeting, territory, food security, resilience, etc; different finding have led to the definition of a major question and an objective which form the core structure of the present dissertation. The research question is defined as "how to structure the targeting and identification of areas with high potential to articulate all the emergency and development actions carried out on several scales of analysis?”. At the end of these observations, the objective of this research is "the establishment of a tool to support spatial and temporal decision making in structuring the emergency and development actions and targeting of populations subjected to food insecurity ". Three considerations emerge from this objective and research question: spatiotemporal analysis and targeting, development potentials, rural production systems. The various productions are also studied over a long series in order to consider the yield variations over time. Finally, these two analyzes, spatial (systems) and temporal (yields) are crossed in order to demonstrate the contribution of this decision-supporting tool in the articulation and structuring of the other two levels of targeting populations to food insecurity. The decision-supporting tool has been tested on the case study of the Nigerian population. The main outcomes are: the characterization of the opportunities and constraints of the Nigerian rural production systems; the identification of the products to be developed by production system; the identification of the most promising pathways by means of the distribution of the yields by systems. Finally, an essential point must be made about the increase of conservation methods and transformations for increasing the added value obtained by Nigerian households. At the end of this dissertation, the tool demonstrated its importance in structuring and articulating the targeting of food insecurity in the field of emergency aid and development: The territorial zones in the production systems identify the problems to which one or several solutions must be found. Production systems allow a concentration of actions according to the definition of the general and specific objectives of the agricultural development assistance programs. Potential outputs to be developed in production systems allow diversification of agriculture and structuring of development from a national point of view. The actions defined by the Technical and Financial Partners at the level of a village, a community and / or a commune can be more easily integrated into this scale of analysis and can be structured later in national development policies Agricultural policy. The increase in productivity in Niger depends on the development of products within the most favorable zones and not on the whole territory. However, this tool is complementary to the other targeting tools already in place. It should also be complemented by the same type of analysis at the level of West Africa and an analysis of the flows and prices condition to favor the flow of production. [less ▲]

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See detail“Flippons nos classes de FLE !" : Le modèle de classe inversée adopté à l’université de Liège pour l’enseignement/apprentissage du FLE
Thonard, Audrey ULiege

Conference (2017, September 21)

Dix ans après la création d’un premier dispositif d’apprentissage en ligne, l’Institut Supérieur des Langues Vivantes a souhaité revoir son intégration du numérique dans les cours de FLE destiné aux ... [more ▼]

Dix ans après la création d’un premier dispositif d’apprentissage en ligne, l’Institut Supérieur des Langues Vivantes a souhaité revoir son intégration du numérique dans les cours de FLE destiné aux étudiants Erasmus « in ». Dans cette communication, nous présenterons les contraintes et les opportunités qui ont modifié, lentement mais sûrement, notre conception de l’enseignement en ligne et celle de la classe inversée. [less ▲]

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See detailLa communication scientifique directe vers un public élargi. L’actualité sociale traitée par des chercheurs dans les carnets de recherche Hypothèses
Mayeur, Ingrid ULiege

in Revue Française des Sciences de l'Information et de la Communication (2017), 11

This contribution aims to examine a social mediation allowed by the open access, which is imparting knowledge in Social Sciences and Humanities (thereafter SSH) through a broader public. I will consider ... [more ▼]

This contribution aims to examine a social mediation allowed by the open access, which is imparting knowledge in Social Sciences and Humanities (thereafter SSH) through a broader public. I will consider the platform OpenEdition (and specifically Hypothèses that concerns academic blogging) as a ground of investigation. The matter will be a specific way to impart knowledge, which is the treatment of the actuality by researchers through their reading grids in SSH. In the corpus analysis, I will stress the appropriation modes of the device by the researchers that comment the actuality, the expected audience and practices that the texts suggest, and the discursive processes that are used. I also will question how “direct” such scientific communication is on an academic blog published on a platform in open access. [less ▲]

Detailed reference viewed: 58 (0 ULiège)
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See detailOscar Orban est-il l'Albert Dicey du plat pays?
Bouhon, Frédéric ULiege

Conference (2017, September 20)

L'exposé porte sur la personnalité d'Oscar Orban, professeur de droit public à l'Université de Liège au début du 20e siècle. Elle se focalise sur son oeuvre majeure, "Le droit constitutionnel de la ... [more ▼]

L'exposé porte sur la personnalité d'Oscar Orban, professeur de droit public à l'Université de Liège au début du 20e siècle. Elle se focalise sur son oeuvre majeure, "Le droit constitutionnel de la Belgique", publiée en trois volumes entre 1906 et 1911. [less ▲]

Detailed reference viewed: 10 (0 ULiège)
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See detailThe Vedic Consecration and the Birth of the Hero in Sanskrit Epic
Swennen, Philippe ULiege

Conference (2017, September 20)

When they give birth to these heros, Arjuna's mother and Râma's mother are both compared to the Vedic goddess Aditi. This suggests that the author of the Mahâbhârata was comparing Arjuna to a Vedic ... [more ▼]

When they give birth to these heros, Arjuna's mother and Râma's mother are both compared to the Vedic goddess Aditi. This suggests that the author of the Mahâbhârata was comparing Arjuna to a Vedic sacrificer, which was perfectly clear for the author of the Râmâyana inspired by the Mahâbhârata. [less ▲]

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See detailRéflexions sur la vie et la carrière de M. Pierre Pescatore
Van Cleynenbreugel, Pieter ULiege

Scientific conference (2017, September 20)

In this presentation, I offered an overview of the life, career and lasting impact of the scholarship and practice of M. Pierre Pescatore, former judge at the Court of Justice of the European Union and ... [more ▼]

In this presentation, I offered an overview of the life, career and lasting impact of the scholarship and practice of M. Pierre Pescatore, former judge at the Court of Justice of the European Union and professor at the University of Liège. [less ▲]

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See detailLegitimating innovation by foreign traditions: the case of the Roman Republican divination
Berthelet, Yann ULiege

Conference (2017, September 20)

Detailed reference viewed: 19 (0 ULiège)
See detailLipin-1 regulates cancer cell phenotype and is a potential target to amplify the effect of metabolic inhibitors
Brohée, Laura ULiege

Doctoral thesis (2017)

An increased lipogenesis was reported in various cancers and its inhibition represses proliferation and induces apoptosis of cancer cells while barely affecting most normal cells. The family of lipins ... [more ▼]

An increased lipogenesis was reported in various cancers and its inhibition represses proliferation and induces apoptosis of cancer cells while barely affecting most normal cells. The family of lipins encompasses three members: lipin-1, -2 and -3. All exhibit dual functions as enzymes, catalyzing the de-phosphorylation of phosphatidic acid to diacylglycerol, and as co-transcriptional regulators. Thus, they are able to regulate lipid homeostasis at several nodal points. However, no studies addressed the involvement of these proteins in cancer progression neither in vitro nor in vivo. During this PhD work, we first investigated the importance of lipin-1 on prostate cancer cell phenotype. We showed that lipin-1 expression is increased in various cancer cell types both in vitro and in vivo in human prostate tumor samples. The specific inhibition of lipin-1 in prostate and breast cancer cells demonstrated its critical importance for cell proliferation and migration through deregulation of several intracellular signaling pathways. This study demonstrated for the first time that the targeting of lipin-1 is a potential new anti-cancer strategy that could be used alone or in combination with drugs like rapamycin. During the course of these investigations, we also observed a compensatory regulation between lipin-1 and lipin-2 preventing the complete inhibition of lipins enzymatic activity when using a siRNA approach. Therefore, we focused our interest on inhibiting all lipins through treatment with a pharmacological inhibitor, propranolol. This drug also induced a blockade of the late phases of autophagy, likely because the inhibition of all lipins decreases diacylglycerol synthesis, which is required for the maturation of autolysosomes. Autophagy is a pro-survival mechanism induced by several stresses or by anticancer agents. In the case of the glycolysis inhibitor 2DG, the induction of autophagy limits its anticancer effects in monotherapy. In the light of their individual specific effects on cancer cells, we hypothesized that the combination of propranolol and 2DG might exert a more than additive toxic effect on cancer cells. In this second study, we report that combined treatment is effective on preventing prostate cancer cell proliferation, inducing cell apoptosis, altering the function of several organelles as mitochondria, endoplasmic reticulum and Golgi apparatus in vitro but also in suppressing tumor growth in vivo. Altogether, our data suggest that lipins are key players involved in cancer progression. Targeting lipins, alone or in combination with other treatments, could open new avenues in anticancer therapy. [less ▲]

Detailed reference viewed: 26 (4 ULiège)
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See detailWP1 - A summary
Sanchez, Christelle ULiege

Conference (2017, September 20)

Detailed reference viewed: 12 (0 ULiège)