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See detailQu'est-ce que la philosophie politique ?
Delruelle, Edouard ULg

Scientific conference (2015, May 11)

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See detailEtude de la matière sombre par effet de mirage gravitationnel
Biernaux, Judith ULg

Scientific conference (2015, May 11)

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See detailAntimicrobial, antitumor and brine shrimp lethality assay of Ranunculus arvensis L. extracts
Muhammad Zeeshan Bhatti; Ali, Amjad ULg; Asma Saeed et al

in Pakistan Journal of Pharmaceutical Sciences (2015)

To investigate the antitumor activity, brine shrimp lethality assay, antibacterial and antifungal activity of Methanol Extract (ME), Water Extract (WE), Acetone Extract (AE), Chloroform Extract (CE ... [more ▼]

To investigate the antitumor activity, brine shrimp lethality assay, antibacterial and antifungal activity of Methanol Extract (ME), Water Extract (WE), Acetone Extract (AE), Chloroform Extract (CE), Methanol-Water Extract (MWE), Methanol-Acetone Extract (MAE), Methanol-Chloroform Extract (MCE) of Ranunculus arvensis (L.). Antitumor activity was evaluated with Agrobacterium tumefaciens (At10) induced potato disc assay. Cytotoxicity was evaluated with brine shrimp lethality assay. Antibacterial activity was evaluated with six bacterial strains including Escherichia coli, Enterobacter aerogenes, Bordetella bronchiseptica, Klebsiella pneumoniae, Micrococcus luteus and Streptococcus anginosus and antifungal screening was done against five fungal strains including Aspergillus niger, A. flavus, A. fumigates, Fusarium solani and Mucor species by using disc diffusion method. Best antitumor activity was obtained with ME and WE, having highest IC50 values 20.27±1.62 and 93.01±1.33μg/disc. Brine shrimp lethality assay showed LC50 values of AE, MAE and ME were obtained as 384.66±9.42μg/ml, 724.11±8.01μg/ml and 978.7±8.01μg/ml respectively. WE of R. arvensis revealed weak antimicrobial result against the tested microorganisms. On the other hand, the antifungal activity of the plant extracts was found to be insignificant. These findings demonstrate that extracts of R. arvensis possesses significant antitumor activity. Further extensive study is necessary to assess the therapeutic potential of the plant [less ▲]

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See detailLipin-1 regulates cancer cell phenotype and is a potential target to potentiate rapamycin treatment
Brohée, Laura ULg; Demine, Stéphane; Willems, Jérôme ULg et al

in Oncotarget (2015), 6(13), 11264-11280

Lipogenesis inhibition was reported to induce apoptosis and repress proliferation of cancer cells while barely affecting normal cells. Lipins exhibit dual function as enzymes catalyzing the ... [more ▼]

Lipogenesis inhibition was reported to induce apoptosis and repress proliferation of cancer cells while barely affecting normal cells. Lipins exhibit dual function as enzymes catalyzing the dephosphorylation of phosphatidic acid to diacylglycerol and as co-transcriptional regulators. Thus, they are able to regulate lipid homeostasis at several nodal points. Here, we show that lipin-1 is up-regulated in several cancer cell lines and overexpressed in 50 % of high grade prostate cancers. The proliferation of prostate and breast cancer cells, but not of non-tumorigenic cells, was repressed upon lipin-1 knock-down. Lipin-1 depletion also decreased cancer cell migration through RhoA activation. Lipin-1 silencing did not significantly affect global lipid synthesis but enhanced the cellular concentration of phosphatidic acid. In parallel, autophagy was induced while AKT and ribosomal protein S6 phosphorylation were repressed. We also observed a compensatory regulation between lipin-1 and lipin-2 and demonstrated that their co-silencing aggravates the phenotype induced by lipin-1 silencing alone. Most interestingly, lipin-1 depletion or lipins inhibition with propranolol sensitized cancer cells to rapamycin. These data indicate that lipin-1 controls main cellular processes involved in cancer progression and that its targeting, alone or in combination with other treatments, could open new avenues in anticancer therapy. [less ▲]

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See detailFoamability and Foam Stability of Male and Female Date Palm Sap (Phoenix dactylifera L.) During the Collection Period
Makhlouf-gafsi, Ines; Mokni-ghribi, Abir; Bchir, Brahim et al

in Food Biophysics (2015)

This work aimed to study the influence of date palm sex on the surface properties of date palm sap (DPS) (Phoenix dactylifera L.) during the collection period. The behavior at the interface and foaming ... [more ▼]

This work aimed to study the influence of date palm sex on the surface properties of date palm sap (DPS) (Phoenix dactylifera L.) during the collection period. The behavior at the interface and foaming properties were evaluated via equilibrium surface tension (drop volume) and bubbling method, respectively. Unlike male sap, the female sap was unable to produce foam due to its low rate of adsorption, low average hydrophobicity values, and low bulk viscosity values throughout the collection period. For male sap, there are significant differences (p<0.05) on foaming properties throughout the collection period. In fact, the last 3 weeks of sap collection were characterized by a decrease pace of surface tension which explains the enhancement of both foam capacity and stability. The last week of collection period present the best foam power (0.9). To explain these differences, the interactions of several factors and their affects on foaming properties were examined. Results showed a positive correlation between foam capacity and average hydrophobicity values. In the other hand, foam stability exhibits a positive correlation with the increase of protein concentration and bulk viscosity. [less ▲]

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See detailTiO2 templated films used as photoelectrode for solid-state DSSC applications: Study of the solid electrolyte infiltration by Rutherford Backscattering Spectrometry
Dewalque, Jennifer ULg; Colson, Pierre ULg; Mathis, François et al

Poster (2015, May 10)

Liquid-state dye-sensitized solar cells can suffer from electrolyte evaporation and leakage. Therefore solid-state hole transporting materials are investigated as alternative electrolyte materials ... [more ▼]

Liquid-state dye-sensitized solar cells can suffer from electrolyte evaporation and leakage. Therefore solid-state hole transporting materials are investigated as alternative electrolyte materials. However, in solid-state dye-sensitized solar cells, optimal TiO2 films thickness is limited to a few microns allowing the adsorption of only a low quantity of photoactive dye and thus leading to poor light harvesting and low conversion efficiency. In order to overcome this limitation, high surface area templated films are investigated as alternative to nanocrystalline films prepared by doctor-blade or screen-printing. Moreover, templating is expected to improve the pore accessibility what would promote the solid electrolyte penetration inside the porous network, making possible efficient charge transfers. In this study, films prepared from different structuring agents are discussed in terms of microstructural properties (porosity, crystallinity) as well as effect on the dye loading and Spiro-OMeTAD (2,2',7,7'-tetrakis-(N,N-di-p-methoxyphenylamine)9,9'-spirobifluorene) solid electrolyte filling. Different techniques such as transmission electron microscopy (TEM), atmospheric poroellipsometry (AEP) and UV-visible absorption spectroscopy (UV-vis.) have been used to describe the microstructural features of the films. Besides, we have implemented Rutherford backscattering spectrometry (RBS) as an innovative non-destructive tool to characterize the hole transporting materials infiltration. Templated films show dye loading more than two times higher than nanocrystalline films prepared by doctor-blade or screen-printing and solid electrolyte infiltration up to 88%. [less ▲]

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See detailPrevention of Synovial Membrane Inflammation & Cartilage Degradation by a Novel Chitosan
Henrotin, Yves ULg; Oprenyeszk, Frédéric ULg; Dubuc, Jean-Emile et al

Conference (2015, May 10)

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See detailMéthodes et innovations pédagogiques en enseignement supérieur
Hanzen, Christian ULg

Learning material (2015)

Cette présentation Power point a été réalisée dans le cadre d'un cycle de conférences données à la faculté de Médecine Vétérinaire de Constantine les 9 et 10 mai 2015. Elle aborde trois aspects ... [more ▼]

Cette présentation Power point a été réalisée dans le cadre d'un cycle de conférences données à la faculté de Médecine Vétérinaire de Constantine les 9 et 10 mai 2015. Elle aborde trois aspects complémentaires à savoir les étudiants, les méthodes et les évaluations. [less ▲]

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See detail"Drôleries". L'iconographie marginale des portails occidentaux et de la nef de la cathédrale de Strasbourg
Van den Bossche, Benoît ULg

Conference (2015, May 09)

Le vaste ensemble sculpté constitué par les trois portails occidentaux de la cathédrale de Strasbourg a fait l’objet, ces dernières années, de plusieurs études. Une critique d’authenticité a été menée ... [more ▼]

Le vaste ensemble sculpté constitué par les trois portails occidentaux de la cathédrale de Strasbourg a fait l’objet, ces dernières années, de plusieurs études. Une critique d’authenticité a été menée ; les choix iconographiques qui ont présidé à l’élaboration du programme ont été déterminés et justifiés. Toutes ces études ont pourtant laissé de côté une centaine de reliefs finement sculptés qui agrémentent les parties hautes du niveau des portails, à l’extérieur comme à l’intérieur de la façade. Cette iconographie, authentique pour l’essentiel, se distingue par une grande variété de « sujets ». A priori, elle rappelle celle des « drôleries » des manuscrits de la fin du XIIIe siècle et du XIVe. Mais est-ce le cas ? Et si c’est le cas, comment articuler ces sujets qui ont jusqu’à aujourd’hui été considérés comme marginaux, avec l’iconographie des ébrasements, des tympans et des voussures ? Enfin, l’ensemble de « drôleries » de la cathédrale de Strasbourg peut-il, d’un point de vue iconographique, être comparé à d’autres ensembles sculptés français et germaniques de la fin du XIIIe siècle et du XIVe ? [less ▲]

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See detailPartial volume effect impact on PET preclinical dosimetry: a simulation study
Seret, Alain ULg; Bahri, Mohamed Ali ULg; Bretin, Florian et al

Conference (2015, May 09)

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See detailRADIOPHARMACY GMP QC HPLC VALIDATION
Aerts, Joël ULg; Giacomelli, Fabrice ULg; Hubert, Philippe ULg et al

Conference (2015, May 09)

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See detailEt si nos déchets devenaient de nouveaux produits: notion d'économie circulaire
Richel, Aurore ULg

Conference given outside the academic context (2015)

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See detailPrésentation de ModerNum
Regibeau, Julien ULg; Simon, Nicolas; Guri, Shipé

Conference (2015, May 08)

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See detailGrammaire matérielle et erreur de catégorie
Leclercq, Bruno ULg

Conference (2015, May 08)

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See detailTipTopLam - Rapid manufacturing laser de pièces en titane (2008-2015), volet 1: Caractérisation microstructurale
Carton, Marc; Contrepois, Quentin; Mertens, Anne ULg et al

Report (2015)

Detailed reference viewed: 7 (1 ULg)