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See detailCone beam ct new tool in diagnostic imaging
DE MARNEFFE, Mikaël ULiege; MILICEVIC, Marina; MILICEVIC, Mladen ULiege

in Revue Médicale de Liège (2017), 72(10), 457-461

Le but de cet article est de présenter les avantages de la tomographie computérisée à faisceau conique (CBCT) par rapport à la tomographie computérisée (CT) classique et de rapporter quelques applications ... [more ▼]

Le but de cet article est de présenter les avantages de la tomographie computérisée à faisceau conique (CBCT) par rapport à la tomographie computérisée (CT) classique et de rapporter quelques applications cliniques. Inventé pratiquement pour les dentistes, en particulier pour l'implantologie, le CBCT a trouvé une indication incontournable dans l'imagerie des sinus, de la chirurgie maxillo-faciale et orale, en parodontologie, endodontie et orthodontie. Le CBCT s 'est avéré utile également dans l'imagerie des lésions de différentes origines des mâchoires avec, toutefois, une réserve concernant le bilan d'atteinte des tissus mous (dans ce cas, une IRM - ou un CT avec injection de produit de contraste - serait préférable). Dernièrement, l'application du CBCT s'est élargie à l'imagerie du rocher et, même, des petites articulations des extrémités. [less ▲]

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See detailDétermination des propriétés physico-mécaniques et de durabilité d'un lot de planches de hêtre traitées thermiquement
Pollet, Caroline; Hebert, Jacques ULiege; Jourez, Benoît ULiege

Report (2017)

La scierie Scidus est intéressée de caractériser la qualité de son bois de hêtre traité thermiquement. Une étude a été mise en place au LTB en collaboration avec l’Ulg dans le cadre d'une colaboration ... [more ▼]

La scierie Scidus est intéressée de caractériser la qualité de son bois de hêtre traité thermiquement. Une étude a été mise en place au LTB en collaboration avec l’Ulg dans le cadre d'une colaboration avec la scierie Scidus d'Etalle. Les objectifs de cette étude sont de déterminer l’effet du traitement sur les propriétés physico-mécaniques usuelles et d’évaluer la durabilité conférée des bois récemment traités. [less ▲]

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See detailPrevalence and capsular-polysaccharide type distribution of colonizing group B streptococci (GBS) isolated from recto-vaginal samples in pregnant women in Hanoï, Vietnam
MEEX, Cécile ULiege; DEVEY, Anaïs ULiege; PHAM HONG, Nhung et al

Poster (2017, October)

Background: The study was organized by the Belgian National Reference Center (NRC) for Streptococcus agalactiae or GBS, and carried out in Vietnam. The aim of the study was to determine the prevalence of ... [more ▼]

Background: The study was organized by the Belgian National Reference Center (NRC) for Streptococcus agalactiae or GBS, and carried out in Vietnam. The aim of the study was to determine the prevalence of GBS colonization among pregnant women in Hanoï and to characterize the capsular-polysaccharide (CPS) type of the isolated strains. Methods: For a 2-months period in 2015, 888 recto-vaginal swabs were collected in Bach-Mai-Hospital from pregnant women at 35-37 weeks’ gestation and were cultured for detection of GBS. Strains were stored and transferred to the Belgian NRC for further characterization. CPS-typing was performed by both latex agglutination and PCR (Poyart, 2007; Kong, 2008). Results: Among the 888 swabs, 111 were positive for GBS, that is a prevalence of colonization of 12.5%. A total of 90 strains were available for typing: 91,11% could be serotyped by latex agglutination and all the strains, including the 8 phenotypically non-typable strains, were successfully genotyped. CPS type V was the most prevalent (36.7%) followed by CPS types Ib (25.6%), III (21.1%), VI and VII (8.9% and 4.4%). CPS type II was found twice and serotype Ia was found once. CPS types IV, VIII and IX weren’t present in this population. Conclusion: With predominance of types V, Ib and III, this distribution of CPS-types of GBS colonizing pregnant women in Hanoï, Vietnam, differs from distributions described in Europe and in o Asian countries. This study provides useful information for the development of a universal vaccine that could contribute to improve the prevention of neonatal GBS infections. [less ▲]

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See detailPrevalence and characteristics of group B streptococcus colonization in HIV-infected pregnant women in Belgium
DAUBY, Nicolas; ADLER, Catherine; Y MIENDJE DEYI, Véronique et al

Poster (2017, October)

Objectives: High incidence of GBS sepsis has been reported in HIV-exposed but uninfected (HEU) infants in both developed and developing countries, particularly late-onset diseases. We aimed determining ... [more ▼]

Objectives: High incidence of GBS sepsis has been reported in HIV-exposed but uninfected (HEU) infants in both developed and developing countries, particularly late-onset diseases. We aimed determining the prevalence, the characteristics and the risk factors of GBS carriage in HIV-infected and HIV uninfected pregnant women (PW). Methods : Between 1/01/2011 and 31/12/2013, HIV-infected (n=132) and uninfected (n=123) PW had recto-vaginal swabs for GBS detection performed at 35-37 weeks of gestation and at deliver Demographic, obstetrical and medical data related to HIV-infection were prospectively collected. Serotyping of GBS strains was performed on a limited number of randomly selected samples (26 from HIV-infected and 13 from uninfected PW). Results : The overall prevalence of GBS carriage was not statistically different between HIV-infected and uninfected PW (31% vs 24,4% respectively). Age, nadir CD4 cell count, CD4 cell count at delivery and detectable viral load at delivery were not associated with GBS carriage rate in HIV-infected PW. A distinct pattern of GBS serotype was found in HIV-infected PW who were predomina colonized by serotype III (12/26) while HIV-uninfected PW were mostly colonized by serotype Ia (8/13) (p<0,05). Conclusions: As previously reported in other countries, HIV-infected PW do not have significantly higher rate of GBS colonization. However, our results suggest that HIV-infected PW are more lik be colonized with serotype III strains, that is the main serotype associated with late-onset neonatal sepsis. Ongoing research aims at characterizing the clonal features of the isolated strains [less ▲]

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See detailEvolution of rate and genotypes of resistance to macrolide/lincosamide among invasive Group B Streptococcus (GBS): Development of a multiplex PCR tool for simultaneous detection of ErmB, ErmTr, MefA and LsaC resistance genes.
SACHELI, Rosalie ULiege; DESCY, Julie ULiege; MEEX, Cécile ULiege et al

Poster (2017, October)

Methods: A multiplex-PCR, using a set of specifically designed or already described (Kataja, 1999; Malbruny, 2011) primers was developed and used to detect, in GBS, three genes for erythromyc resistance ... [more ▼]

Methods: A multiplex-PCR, using a set of specifically designed or already described (Kataja, 1999; Malbruny, 2011) primers was developed and used to detect, in GBS, three genes for erythromyc resistance, ermB, ermTR, mefA and one gene for clindamycin-resistance lsaC. AdhP gene amplification was used as control for GBS identification. All(219) GBS isolates from invasive infections in newborns and adults received by the Belgian National Reference Center for GBS in 2015, and control strains were tested for erythromycin/clindamycin susceptibility (disk-diffusion/broth- microdilution) and for detection of resistance genes. Results: PCR products demonstrated the expected respective sizes. The method has been validated successfully according to ISO15189 analytical requirements. Of the 219 isolates, 67(30,67%) w resistant to erythromycin and/or clindamycin: 44/67(65,78%) showed a constitutive-MLS phenotype and 10/67(14,9%) the inducible-MLS phenotype. Among the constitutive-MLS strains, 73% harboured ErmB gene, 13% ErmTR, 7% ErmB+mefA and 7% ermB together with LsaC gene. The inducible-MLS strains harboured mostly ErmTr gene (89%) and the others the ErmB gene. Among the 10/67(14,9%) GBS strains with an M-phenotype (isolated resistance to erythromycin), the MefA gene was exclusively detected. Among the 3(4,48%) strains showing an isolated resistance to clindamycin (L-phenotype), the LsaC gene was detected. Conclusion: The developed multiplex PCR is able to detect simultaneously four genes involved in MLS resistance in GBS. In 2015, 30,6% of the invasive GBS strains isolated in Belgium were resist to macrolides and/or lincosamides. The emergence of the L-phenotype in GBS described since 2010, justifies the relevance to also detect LsaC gene together with ErmB, ErmTr and MefA. [less ▲]

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See detailUpdate of the characteristics of Group B Streptococci (GBS) colonizing pregnant women in Belgium: capsular-type distribution, pili characterization, antimicrobial susceptibility profile and Multiple Locus Sequence Types.
SACHELI, Rosalie ULiege; MEEX, Cécile ULiege; DESCY, Julie ULiege et al

Poster (2017, October)

Aim: Improving knowledge and characterization of GBS strains colonizing pregnant women in Belgium. Methods: In 2013, collection of 387 strains of GBS from 80 laboratories participating in a national ... [more ▼]

Aim: Improving knowledge and characterization of GBS strains colonizing pregnant women in Belgium. Methods: In 2013, collection of 387 strains of GBS from 80 laboratories participating in a national survey among pregnant woman. For each strain, determination of capsular-polysaccharide type agglutination and PCR, of pili-type by PCR and of antimicrobial susceptibility by disk-diffusion, broth-microdilution and detection of resistant genes by PCR. For serotype III strains, determination sequence-type by Multiple-Locus Sequence-Typing (MLST). Results: Serotype III was the most prevalent (28.5%) followed by serotypes V, Ia, II, IV and Ib (20.4%, 19.9%, 17.8%, 7%, 5.4%). Serotypes VI, VII and IX were found each once. All strains remained susceptible to penicillin (MICs: 0.03-0.125 mg/L) and other beta-lactams tested; 28.7% were resistant to erythromycin and 26.7% to clindamycin. With regards to pili, all 387 strains harboured one the PI-2 variants alone or in combination and 70.3% contained PI-1. The 110 serotype III isolates were resolved into 18 STs. The most common were ST-17 (35.5%) followed by ST-19 (30%) and ST- ST-27, ST-23 (<=5%). Conclusion: Among GBS from colonized pregnant women in Belgium: capsular-type and pili distributions, and MLST profile among type III strains were quite similar to reported data from Europ and USA during the last decade. As showed in this study, penicillin remains the first line drug of choice. On the contrary, resistance rates against macrolides/lincosamide, has reached a plateau since a decade, but it is noteworthy to notify the emergence of strains with isolated resistance to clindamycine. [less ▲]

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See detailInvestigation on optimal spray properties for ground based agricultural applications using deposition and retention models
De Cock, Nicolas ULiege; Massinon, Mathieu ULiege; Ouled Taleb Salah, Sofiene ULiege et al

in Biosystems Engineering (2017), 162

In crop protection, it is well known that droplet size determine spray efficacy. The optimisation of both spray deposition and retention leads to a dilemma: should small droplets be used to increase ... [more ▼]

In crop protection, it is well known that droplet size determine spray efficacy. The optimisation of both spray deposition and retention leads to a dilemma: should small droplets be used to increase retention or large droplets be preferred to avoid drift? An ideal droplet should have a short time of flight to minimise its distance travelled while impacting the target with a moderate kinetic energy. This paper aims to determine an optimum range of droplet sizes for boom-sprayer applying herbicide using a modelling approach. The main parameters of spray deposition and retention models are systematically varied and the effects on drift potential and droplet impaction outcomes are discussed. The results of the numerical simulations showed that droplets with diameter ranging between 200 μm and 250 μm offer high control of deposition by combining a low drift potential and a moderate kinetic energy at top of the canopy. A fourfold reduction of the volume drifting further than 2 m from the nozzle was observed for a spray with a volume median diameter of 225 μm when the relative span factor of the droplet spectrum was reduced from 1.0 to 0.6. In the latter scenario, an increase from 63 to 67% of the volumetric proportion of droplets adhering to the wheat leaf was observed. Therefore, strategies for controlling the droplet size distribution may offer promising solutions for reducing adverse impact of spray applications on environment. [less ▲]

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See detailRome Statute of the International Criminal Court
Deprez, Christophe ULiege

in Scobbie, Ian; d'Aspremont, Jean; Brölmann, Catherine (Eds.) Oxford International Organizations (2017)

This note discusses the background, content and overall impact on the 'common law' of international organizations of the Rome Statute of the International Criminal Court.

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See detailInternational Criminal Court Rules of Procedure and Evidence
Deprez, Christophe ULiege

in Scobbie, Ian; d'Aspremont, Jean; Brölmann, Catherine (Eds.) Oxford International Organizations (2017)

This note discusses the background, content and overall impact on the 'common law' of international organizations of the Rules of Procedure and Evidence of the International Criminal Court.

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See detailATYPICAL DICTYOCAULUS VIVIPAROUS-ASSOCIATED BOVINE ACUTE PNEUMONITIS: REMINISCENT OF LARVAL HYPOBIOSIS DURING THE WINTER?
Bayrou, Calixte ULiege; Dernier, Adrienne ULiege; Cassart, Dominique ULiege et al

Conference (2017, October)

Dictyocaulus viviparus is the aetiological agent of verminous bronchitis in cattle. Herein we describe an atypical case of parasitic pneumonitis in an adult cow. Methods At the end of March 2017, a 3-yr ... [more ▼]

Dictyocaulus viviparus is the aetiological agent of verminous bronchitis in cattle. Herein we describe an atypical case of parasitic pneumonitis in an adult cow. Methods At the end of March 2017, a 3-yr old Belgian Blue cow suddenly displayed a marked respiratory distress syndrome a few hours after C-section calving. In spite of the treatment set up by the local veterinarian, the cow died 48 hours later. The body was referred to the Veterinary Faculty of Liège (Belgium) for necropsy. Post- mortem gross examination revealed a severe, acute interstitial pneumonitis with concurrent emphysema and a significant amount of parasites (Dictyocaulus viviparus) in the bronchi. The microscopic examination confirmed the severe acute interstitial pneumonitis with foci of hemorrhages, necrosis, hyaline membranes and hyperplasia of type II pneumocytes. Larvae were also present in the alveoli and bronchioles. Results Altogether, theses clinical observations and lesions were compatible with a hypersensitivity reaction against worm antigens. Additionally, Baermann’s test was performed on feces collected from the cadaver and from 5 others cows kept under the same conditions. Four out of 6 cows were excreting small amounts of Dictyocaulus stage-1 larvae. Conclusions Parasitic pneumonia is a very common disease in first year grazing young cattle. In this case, cow’s age and disease manifestation time were very uncommon. Three-year-old cows are supposed to be fully protected against this nematode species. Moreover, in Belgium, at the end of March, livestock is still kept indoors (zero grazing winter period). Therefore, this case could highlight the hypobiotic capacity of Dictyocaulus viviparus larvae and associated « periparturient rise » phenomenon, both well known in sheep, but not described in cattle so far. We herein discuss the farming conditions that promoted such a severe parasitic respiratory disease. [less ▲]

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See detailVive les hauts-fourneaux! Vers la reconnaissance du patrimoine sidérurgique en Wallonie
Drouguet, Noémie ULiege; Bodeux, Philippe

Book published by Dérivations (2017)

Marcinelle, Ougrée, Clabecq. Trois hauts-lieux de production de fonte et d'acier, dominés par la figure emblématique des hauts-founeaux. A l'arrêt depuis plusieurs années, devenus des friches, ils sont ... [more ▼]

Marcinelle, Ougrée, Clabecq. Trois hauts-lieux de production de fonte et d'acier, dominés par la figure emblématique des hauts-founeaux. A l'arrêt depuis plusieurs années, devenus des friches, ils sont appelés à disparaître prochainement. Avant qu’ArcelorMittal et Duferco ne rasent ces vestiges, les questions de régénération des sites et de préservation du patrimoine sont à étudier conjointement. Fermées, grillagées et laissées à l’abandon, ces forêts industrielles doivent s’ouvrir à ceux qui ont des propositions à défendre, qu'ils soient urbanistes, architectes, promoteurs, artistes, passeurs de mémoire. Les bassins voisins –la Ruhr, la Sarre ou la Lorraine – ont chacun gardé des témoins de l’épopée industrielle pour les recycler en parcs paysagers, musées, ville nouvelle ou espaces économiques. Point de départ de la révolution industrielle sur le continent, la Wallonie ne peut faire l’impasse sur une réflexion approfondie concernant le devenir des friches sidérurgiques. Ce numéro hors-série de Dérivations pose la question et tente de documenter le débat, plus complexe qu'il n'y paraît. Il entend à la fois plonger dans une réalité où se mêlent ville et industrie, en décrire ce qui échappe aux regards, mais aussi donner la parole à ceux qui l’ont côtoyée de près et amener quelques propositions. [less ▲]

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See detailMouvante polyphonie de Claudio Magris. Claudio Magris, un passeur européen aux mille voix
Curreri, Luciano ULiege

Article for general public (2017)

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See detailAeronomy of the Venus Upper Atmosphere
Gérard, Jean-Claude ULiege; Bougher, Stephen .W.; López-Valverde, Miguel .A. et al

in Space Science Reviews (2017)

We present aeronomical observations collected using remote sensing instruments on board Venus Express, complemented with ground-based observations and numerical modeling. They are mostly based on VIRTIS ... [more ▼]

We present aeronomical observations collected using remote sensing instruments on board Venus Express, complemented with ground-based observations and numerical modeling. They are mostly based on VIRTIS and SPICAV measurements of airglow obtained in the nadir mode and at the limb above 90 km. They complement our understanding of the behavior of Venus’ upper atmosphere that was largely based on Pioneer Venus observations mostly performed over thirty years earlier. Following a summary of recent spectral data from the EUV to the infrared, we examine how these observations have improved our knowledge of the composition, thermal structure, dynamics and transport of the Venus upper atmosphere. We then synthesize progress in three-dimensional modeling of the upper atmosphere which is largely based on global mapping and observations of time variations of the nitric oxide and O2 nightglow emissions. Processes controlling the escape flux of atoms to space are described. Results based on the VeRA radio propagation experiment are summarized and compared to ionospheric measurements collected during earlier space missions. Finally, we point out some unsolved and open questions generated by the recent datasets and model comparisons. [less ▲]

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See detailDroit international pénal approfondi - Documents pédagogiques (2017-2018)
Deprez, Christophe ULiege

Learning material (2017)

Ces documents pédagogiques ont servi de support à un cours de Droit international pénal approfondi, dispensé à l'Université de Lille 2 dans le cadre du M2 "Justice pénale internationale".

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See detailDevelopment of solar energy in Africa : A challenge in terms of resource availability and recycling.
Pirard, Eric ULiege; Belboom, Sandra ULiege

Conference (2017, October)

Focusing on Africa, sun is a renewable resource, free of charge, without any dependency of supply from other countries but implying technologies to transform this resource into electricity. Photovoltaic ... [more ▼]

Focusing on Africa, sun is a renewable resource, free of charge, without any dependency of supply from other countries but implying technologies to transform this resource into electricity. Photovoltaic panels are dedicated to this goal and present several advantages as the free cost of the fuel and no emissions during the production of electricity. These advantages are counterbalanced by the high amount of mineral resources needed, the lifetime of installations, the decreasing yield during operation years and the very limited recycling potential [less ▲]

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See detailCessation of nucleos(t)ide analogue treatment after HBeAg seroconversion is associated with a 4-fold increased risk of relapse in cirrhotic compared to non-cirrhotic patients
Van Hees, S; Bourgeois, S; Van Vlierberghe, H et al

in Hepatology (Baltimore, Md.) (2017, October), 66(S1), 934

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See detailUn « Massive Open Online Course » (MOOC) sur des travaux pratiques en Histologie : le grand écart entre son intégration dans l’enseignement universitaire et l’intérêt du grand public.
Multon, Sylvie ULiege; Pesesse, Laurence ULiege; Weatherspoon, Alodie et al

Conference (2017, October)

L’acronyme anglophone MOOC désigne les « Massive Open Online Courses » que l’on pourrait traduire par « formations en ligne massives ouvertes à tous ». Nés aux États-Unis avec un programme sur ... [more ▼]

L’acronyme anglophone MOOC désigne les « Massive Open Online Courses » que l’on pourrait traduire par « formations en ligne massives ouvertes à tous ». Nés aux États-Unis avec un programme sur l’intelligence artificielle dispensé par l’université de Stanford, ces cours en ligne accessibles gratuitement font miroiter la possibilité d’une démocratisation maximale des savoirs. A ce titre, les MOOC bénéficient des innovations issues du Web 2.0 : ils tirent le meilleur de la rencontre entre les nouveaux usages induits par les réseaux sociaux et les apports de la pédagogique active. Ces cinq dernières années, nous avons dispensé les travaux pratiques en Histologie aux 500 étudiants de première année d’étude de la faculté de Médecine de l’Université de Liège par une méthodologie hybride alliant e-learning et présentiel (Multon et al., 2015). Forte de cette expérience réussie, notre équipe a réalisé un MOOC faisant partie intégrante du cursus de nos étudiants et qui répond à la volonté de partager nos ressources numériques avec un public plus large. Ce MOOC intitulé « Introduction à l’histologie, exploration des tissus du corps humain » est dédié à l’étude des 5 familles de tissus biologiques. Deux parcours pédagogiques permettent d’approfondir différemment la matière et ainsi de mieux correspondre aux objectifs ou motivations de chacun. La première session, hébergée sur la plate-forme FUN (France Université Numérique), s’est déroulée en 6 semaines à partir de février 2017. Au travers de vidéos explicatives contenant des dessins construits au fur et à mesure et des liens avec l’anatomie suivie d’activités interactives telles que la manipulation d’un microscope virtuel, de nombreux quiz et d’activités réalisées avec les pairs, les participants seront capables de reconnaître les différents types cellulaires et tous les éléments qui les entourent afin de comprendre comment ils s’organisent entre eux pour former des tissus aux fonctions spécifiques. A l’issu de chaque module, les apprenants ont la possibilité de réaliser des activités certificatives. L’obtention de 70% à chacune donne lieu à une attestation de suivi avec succès du MOOC. Notre MOOC a attiré 5250 personnes issues de 82 pays. Un sondage à l’inscription (n=841) indique que 42% sont des étudiants et 41% ont une activité professionnelle. Un forum actif a permis de nombreux échanges entre apprenants ou avec l’équipe pédagogique (170 fils de discussion). De nombreux participants ont souligné les aspects didactique, accessible, dynamique et captivant du MOOC. Nos étudiants ont apprécié la possibilité de travailler où et quand ils le souhaitaient tout en étant guidés par la structure des différents modules. Nos premières données montrent que 32% des apprenants ont utilisé le microscope virtuel et que 20% se sont engagés dans les activités certificatives, la moitié d’entre eux les ayant réussies. En conclusion, la première édition de ce MOOC francophone a intéressé un vaste public. Dix pourcents des participants ont obtenu l’attestation finale, la moyenne se situant généralement autour de 5% pour les autres MOOC (Oliveri, 2016). Un sondage final est actuellement analysé, il nous permettra d’étudier le ressenti des apprenants sur les différentes composantes de l’expérience d’apprentissage. [less ▲]

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See detailQ-Codes, version 2.5., tabular list, Georgian version, copy desk. 2017
Jamoulle, Marc ULiege; Kareli, Ana; Natia, Natroshvili

Learning material (2017)

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See detailIdentification of the anteroposterior and mediolateral position of lion paws and tracks using 3D geometric morphometrics
Marchal, Antoine F.J.; Lejeune, Philippe ULiege; de Bruyn, P.J. Nico

in African Journal of Wildlife Research (2017), 47(2), 106-113

Estimating the distribution and status of animal populations is crucial in various fields of biology. Monitoring species via their tracks is controversial due to unreliable recording techniques ... [more ▼]

Estimating the distribution and status of animal populations is crucial in various fields of biology. Monitoring species via their tracks is controversial due to unreliable recording techniques, manipulator bias and substrate variation. Furthermore, subjective identification of the foot that produces each track can lead to significant errors, for example, when assigning tracks made by different feet from the same individual to different individuals. The aim of this research was to develop an accurate, consistent and objective algorithm to identify the anteroposterior (hind/front) and mediolateral (right/left) position from digital threedimensional (3D) models of African lion (Panthera leo) paws and tracks using geometric morphometrics. We manually positioned 12 fixed landmarks on 132 paws and 182 tracks recorded in 3D using digital close-range photogrammetry. We used geometric morphometrics to evaluate and visualize the shape variation between paws and between tracks along the anteroposterior and mediolateral axes, and between paws and tracks. The identification algorithm using linear discriminant analysis with jack-knifed predictions reached a maximum accuracy of 95.45% and 91.21% for paws and tracks, respectively.We recommend the use of this objective position identification algorithm in future studies where tracks are compared between individual African lions. [less ▲]

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