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See detailGold nanorods with phase-changing polymer corona for remotely near-infrared-triggered drug release
Liu, Ji ULg; Detrembleur, Christophe ULg; Grignard, Bruno ULg et al

in Chemistry : An Asian Journal (2014), 9(1), 275-288

Herein, we report a new drug-delivery system (DDS) that is comprised of a near-infrared (NIR)- light-sensitive gold-nanorod (GNR) core and a phase-changing poly(e-caprolactone)- b-poly(ethylene glycol ... [more ▼]

Herein, we report a new drug-delivery system (DDS) that is comprised of a near-infrared (NIR)- light-sensitive gold-nanorod (GNR) core and a phase-changing poly(e-caprolactone)- b-poly(ethylene glycol) polymer corona (GNR@PCL-b-PEG). The underlying mechanism of the drugloading and triggered-release behaviors involves the entrapment of drug payloads among the PCL crystallites and a heat-induced phase change, respectively. A low premature release of the pre-loaded doxorubicin was observed in PBS buffer (pH 7.4) at 37 °C (<10% of the entire payload after 48 h). However, release could be activated within 30 min by conventional heating at 50 °C, above the Tm of the crystalline PCL domain (43.5 °C), with about 60% release over the subsequent 42 h at 37 °C. The NIR-induced heating of an aqueous suspension of GNR@PCL-b- PEG under NIR irradiation (802 nm) was investigated in terms of the irradiation period, power, and concentrationdependent heating behavior, as well as the NIR-induced shape-transformation of the GNR cores. Remotely NIR-triggered release was also explored upon NIR irradiation for 30 min and about 70% release was achieved in the following 42 h at 37°C, with a mild warming (<4 °C) of the surroundings. The cytotoxicity of GNR@PCL-b-PEG against the mouse fibroblastic-like L929 cell-line was assessed by MTS assay and good compatibility was confirmed with a cell viability of over 90% after incubation for 72 h. The cellular uptake of GNR@PCL-b-PEG by melanoma MEL-5 cells was also confirmed, with an averaged uptake of 1250 ( ± 110) particles cell-1 after incubation for 12 h (50 mg mL-1). This GNR@PCL-b-PEG DDS is aimed at addressing the different requirements for therapeutic treatments and is envisaged to provide new insights into DDS targeting for remotely triggered release by NIR activation. [less ▲]

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See detailL’associationnisme ethnique à l’épreuve du temps : étude de cas. Le Movimiento Asociativo de Emigrantes Españoles en Bélgica
Molina Marmol, Maïté ULg

in Actes des journée d’étude du 10 novembre 2011 « Immigration et troisième âge. Vieillir en migration, constats et solutions pour des populations silencieuses » (2014, January)

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See detailMyocardial expression of cytokines influence postoperative outcome after cardiac surgery for congenital cardiac defects
Sprute, Johanna; Heying, Ruth; Buding, Brigitte et al

Conference (2014, January)

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See detailCardiac malformations in neonates born from mothers with gestational diabetes
Antole, Nathalie; Jacquemart, Caroline; GKIOUGKI, Evangelia ULg et al

Conference (2014, January)

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See detailA vibrotactile P300-based BCI for consciousness detection and communication
Lugo, Zulay; Rodriguez, Javi; Lechner, Alexander et al

in Clinical EEG and Neuroscience : Official Journal of the EEG and Clinical Neuroscience Society (ENCS) (2014)

Brain–computer interface (BCI) has been used for many years for communication in severely disabled patients. BCI based on electrophysiological signals has enabled communication, using auditory or visual ... [more ▼]

Brain–computer interface (BCI) has been used for many years for communication in severely disabled patients. BCI based on electrophysiological signals has enabled communication, using auditory or visual stimuli to elicit event-related potentials (ERPs). The aim of this study was to determine whether patients with locked-in syndrome (LIS) could elicit a P300 wave, using a vibrotactile oddball paradigm for establishing somatosensory BCI-based communication. Six chronic LIS patients performed 2electroencephalography (EEG)-based vibrotactile P300 oddball tasks. After a simple mental counting task of the target stimuli, participants were instructed to answer 5 questions by counting the vibration on either the right wrist for “yes” or the left wrist for “no.” All participants were able to elicit a P300 wave using the vibrotactile oddball paradigm BCI task. In the counting task, 4 patients got accuracies of 100% (average above chance). In the communication task, one patient achieved 100% accuracy (average above chance). We have shown the feasibility of eliciting a P300 response using vibrotactile stimulation in patients with LIS. The present study provides evidence that this approach can be used for EEG-based BCI communications in this patient group. This is the first study to prove the feasibility of a BCI based on somatosensory (vibratory) stimulation in a group of braininjured patients. Furthermore, this approach could be used for the detection of consciousness in non-communicating patients due to severe brain injuries. [less ▲]

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See detailLa gestion communautaire des ressources naturelles à l’Est de la R.D.Congo : expérience de l’UGADEC
Mukulumanya, Magnant; Vermeulen, Cédric ULg; Kalinda, A et al

in Parcs & Réserves (2014), 68(4), 11-15

Les provinces du Nord Kivu et du Maniema, à l’est de la R.D.Congo sont confrontés à la destruction de l’environnement, particulièrement dans les parties des territoires de Walikale, Lubero, Punia et ... [more ▼]

Les provinces du Nord Kivu et du Maniema, à l’est de la R.D.Congo sont confrontés à la destruction de l’environnement, particulièrement dans les parties des territoires de Walikale, Lubero, Punia et Lubutu. Alors que les forêts riches en biodiversité sont importantes tant pour l’Etat du fait de leur valeur économique que pour les communautés locales pour leur développement, les menaces qui pèsent sur ces dernières sont légions. Les plus importantes sont les mines, les guerres, le foncier, la légitimité et la légalité, etc. Face à cette situation, en 1998 les communautés locales de ces territoires ont décidé d’initier un nouveau modèle de gestion communautaire des ressources naturelles par la création de réserves gérées par les populations locales. L’objectif de ce modèle est la gestion de biodiversité associée au développement endogène, conduite par une l’Union des Associations de Conservation de Gorilles pour le Développement Communautaire à l’Est de la R.D.Congo (UGADEC). Quinze ans après le début de cette initiative les résultats sont prometteurs. Des actions de conservation ont été mises en place et un développement rural amorcé. Cependant, pour que la gestion communautaire devienne une réalité, il importe qu’un partenariat durable soit établi entre les différents acteurs liés à la gestion des réserves communautaires de l’est. [less ▲]

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See detailDIRECTED INFORMATION TRANSFER IN SCALP ELECTROENCEPHALOGRAPHIC RECORDINGS: INSIGHTS ON DISORDERS OF CONSCIOUSNESS
Marinazzo, Daniele; Gosseries, Olivia ULg; Boly, Mélanie ULg et al

in Clinical EEG and Neuroscience : Official Journal of the EEG and Clinical Neuroscience Society (ENCS) (2014)

Introduction: The neural mechanisms underlying electrophysiological changes observed in patients with disorders of consciousness following a coma remain poorly understood. The aim of this article is to ... [more ▼]

Introduction: The neural mechanisms underlying electrophysiological changes observed in patients with disorders of consciousness following a coma remain poorly understood. The aim of this article is to investigate the mechanisms underlying the differences in spontaneous electroencephalography between patients in vegetative/unresponsive wakefulness syndrome, minimally conscious state, emergence of the minimally conscious state and age-matched healthy control subjects. <br />Methods: Forty recording of spontaneous scalp electroencephalography were performed in 27 patients who were comatose on admission, and on healthy controls. Multivariate Granger Causality and Transfer Entropy were applied on the data. <br />Results: Distinctive patterns of putative bottlenecks of information were associated to each conscious state. Healthy controls are characterized by a greater amount of synergetic contributions from duplets of variables. <br />Conclusion: A novel set of measures was tested to get a novel insight on the pattern of information transfer in a network of scalp electrodes in patients with disorders of consciousness. [less ▲]

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See detailContribution to the macrophytic typology of the Belgian reference watercourses
Galoux, Daniel; Chérot, Frédéric; Rosillon, Francis ULg et al

in International Journal of Water Sciences (2014)

The objective of the study is to create a typology of macrophytes for the reference watercourses of the Meuse River catchment basin in Wallonia, as a step towards the implementation of the European Water ... [more ▼]

The objective of the study is to create a typology of macrophytes for the reference watercourses of the Meuse River catchment basin in Wallonia, as a step towards the implementation of the European Water Framework Directive. The 50 sites studied are the object of a physicochemical and environmental characterisation followed by a floristic survey (phanerogams, mosses, liverworts, and macroalgae). Six clusters of watercourses with their characteristic species are highlighted by two-way clustering and indicator species. The abundance of phanerogams in some watercourses of the Arden region is not only linked to light intensity but also depends on the degree of slope and the nature of the geological substrate. [less ▲]

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See detailFestival du jeu vidéo indépendant : photographie d'une communauté
Hurel, Pierre-Yves ULg

Article for general public (2014)

Le secteur du jeu vidéo indépendant continue de s'organiser et de s'institutionnaliser. En octobre 2013 avait lieu à Montreuil (France) la deuxième édition de son festival européen : l'European ... [more ▼]

Le secteur du jeu vidéo indépendant continue de s'organiser et de s'institutionnaliser. En octobre 2013 avait lieu à Montreuil (France) la deuxième édition de son festival européen : l'European Independant Games Days (EIGD). Celui-ci se présente comme un cycle de conférences sur deux jours durant lesquels les professionnels parlent aux professionnels. L'occasion pour nous de relever quelques débats qui animent le milieu. [less ▲]

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See detailMigrations congolaises (RDC) en Belgique et postcolonialismes
Demart, Sarah ULg

in La lutte contre les discriminations au regard de l’histoire et de la mémoire coloniales : état des lieux (2014, January)

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See detailSperm Motility and Lactate production at different sperm concentrations
Ponthier, Jérôme ULg; De Tullio, Pascal ULg; Blommaert, Didier ULg et al

in Journal of Equine Veterinary Science (2014, January), 34(1), 75-76

Lactate production is associated with total spermatozoa concentration. It negatively affects preservation of total and progressive motility, showing an effect of by-products of anaerobic metabolism on ... [more ▼]

Lactate production is associated with total spermatozoa concentration. It negatively affects preservation of total and progressive motility, showing an effect of by-products of anaerobic metabolism on long-term storage. Moreover, our data show that non-progressive motile spermatozoa are highly associated to lactate concentration, and thus, anaerobic glycolysis. More studies are required to determine relative contributions of aerobiosis and anaerobiosis to spermatozoa motility under different storage conditions. [less ▲]

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See detailUse of automatic stapling device during castration to prevent (re)occurrence of inguinal hernia in horses with large vaginal rings.
Salciccia, Alexandra ULg; de la Rebière de Pouyade, Geoffroy ULg; Ponthier, Jérôme ULg et al

in Journal of Equine Veterinary Science (2014, January), 34(1), 99-100

(Re)ocurrence of inguinal hernia in case of very large vaginal rings may simply be prevented by closure of the vaginal tunic by TA staples during castration by inguinal approach. This method provides a ... [more ▼]

(Re)ocurrence of inguinal hernia in case of very large vaginal rings may simply be prevented by closure of the vaginal tunic by TA staples during castration by inguinal approach. This method provides a good resistance to internal pressure, appears to be safe, fast and easy to perform and may therefore be an interesting alternative to laparoscopic techniques when castration is considered. [less ▲]

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See detailLa transposition didactique en français langue étrangère et seconde
Bento, Margaret; Defays, Jean-Marc ULg; Meunier, Deborah ULg

in Français dans le Monde [=FDLM] : Revue Internationale et Francophone des Professeurs de Français. Recherches et Applications (2014), 55

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See detailUse of rotary atomiser to optimize retention on barley leaves while reducing driftable droplets
Ouled Taleb Salah, Sofiene ULg; Massinon, Mathieu ULg; Boukhalfa, Hassina dite Hafida ULg et al

in International Advances in Pesticide Application, Aspects of Applied Biology 122 (2014, January)

Controlled Droplet Application using rotary atomiser is based on an improved control of droplet size and trajectory comparatively to hydraulic nozzles. On the basis of literature, it was stated that the ... [more ▼]

Controlled Droplet Application using rotary atomiser is based on an improved control of droplet size and trajectory comparatively to hydraulic nozzles. On the basis of literature, it was stated that the use of 60° forward angled spray combined with the narrow drop size distribution of a rotary atomiser could lead to low drift and high retention on monocotyledonous and superhydrophobic weeds at early stage. A Micromax120 atomiser was tuned to emit 270 µm VMD, 60° angled forward, to increase interception by the canopy structure. A spray mixture containing a superspreader adjuvant was used to avoid drop bouncing. An increase of spray retention comparatively to a Teejet 11002 at 1.4 bars was observed, although not proved statistically significant by these preliminary trials. On the drift side, the tilted spinning disc seemed to be advantageous since droplet spectra contains a low percentage of droplets under 100 µm and presents an ejection velocity of 25 m.s-1 at 5000 RPM. The spray drift was reduced about 50%. However, these setting were not found as efficient as expected. Indeed, angled spray proved to be more sensitive to advection and turbulence, as the spray was more exposed to the airflow than for the vertical position. It appears that angling the spray and choosing a drop size spectrum with a Volume Median Diameter as big as 270 µm is not sufficient to reduce significantly this issue. Some alternatives as decreasing the emission height are possible with angled sprays but require height control that seems difficult to reach in practical situations. [less ▲]

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See detailFast chromatographic method for explosive profiling
Stefanuto, Pierre-Hugues ULg; Peyrrault, Katelynn; Focant, Jean-François ULg et al

Conference (2014, January)

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See detailReading the decomposition chemistry of human remains with a new pair of glasses
Stefanuto, Pierre-Hugues ULg; Stadler, Sonja; Perrault, Katelynn et al

Conference (2014, January)

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See detailAutograph/Holograph and Authorial Manuscripts in Arabic Script [Conference Review]
Franssen, Elise ULg

in Comparative Oriental Manuscript Studies Newsletter (2014), 7

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