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See detailMAVEN IUVS observations of the aftermath of Comet Siding Spring's meteor shower
Stewart; Schneider; Plane et al

Conference (2015, March)

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See detailAn efficient flamelet-based combustion model for compressible flows
Saghafian, Amirreza; Terrapon, Vincent ULg; Pitsch, Heinz

in Combustion and Flame (2015), 162(3), 652-667

A combustion model based on a flamelet/progress variable approach for high-speed flows is introduced. In the proposed formulation, the temperature is computed from the transported total energy and ... [more ▼]

A combustion model based on a flamelet/progress variable approach for high-speed flows is introduced. In the proposed formulation, the temperature is computed from the transported total energy and tabulated species mass fractions. Only three additional scalar equations need to be solved for the combustion model. Additionally, a flamelet library is used that is computed in a pre-processing step. This approach is very efficient and allows for the use of complex chemical mechanisms. An approximation is also introduced to eliminate costly iterative steps during the temperature calculation. To better account for compressibility effects, the chemical source term of the progress variable is rescaled with the density and temperature. The compressibility corrections are analyzed in an a priori study. The model is also tested in both Reynolds-averaged Navier–Stokes (RANS) and large-eddy simulation (LES) computations of a hydrogen jet in a supersonic transverse flow. Comparison with experimental measurements shows good agreement, particularly for the LES case. It is found that the disagreement between RANS results and experimental data is mostly due to the mixing model deficiencies and the presumed probability density functions used in the RANS formulation. A sensitivity study of the proposed model shows the importance of the compressibility corrections especially for the source term of the progress variable. [less ▲]

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See detailThe AgMIP Coordinated Climate-Crop Modeling Project (C3MP) : Methods and Protocols
McDermid, S.; Ruane, A.; Hudson, N. et al

in Rosenzweig, Cynthia; Hillel, Daniel (Eds.) Handbook of Climate Change and Agroecosystems: The Agricultural Model Intercomparison and Improvement Project (AgMIP) - Integrated Crop and Economic Assessments (2015)

Climate effects on agriculture are of increasing concern in both the scientific and policy communities because of the growing population and the greater uncertainty in the weather during growing seasons ... [more ▼]

Climate effects on agriculture are of increasing concern in both the scientific and policy communities because of the growing population and the greater uncertainty in the weather during growing seasons. Changes in production are directly linked to variations in temperature and precipitation during the growing season and often to the offseason changes in weather because of soil water storage to replenish the soil profile. This is not an isolated problem but one of worldwide interest because each country has concerns about their food security. The Agricultural Model Intercomparison and Improvement Project (AgMIP) was developed to evaluate agricultural models and intercompare their ability to predict climate impacts. In sub-Saharan Africa and South Asia, South America and East Asia, AgMIP regional research teams (RRTs) are conducting integrated assessments to improve understanding of agricultural impacts of climate change (including biophysical and economic impacts) at national and regional scales. Other AgMIP initiatives include global gridded modeling, data and information technology (IT) tool development, simulation of crop pests and diseases, site-based crop-climate sensitivity studies, and aggregation and scaling. [less ▲]

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See detailCrosstalk between intracellular and extracellular signals regulating interneuron production migration and integration into the cortex
Peyre, Elise ULg; Gomes Da Silva, Carla ULg; Nguyen, Laurent ULg

in Frontiers in Cellular Neuroscience (2015)

During embryogenesis, cortical interneurons are generated by ventral progenitors located in the ganglionic eminences of the telencephalon. They travel along multiple tangential paths to populate the ... [more ▼]

During embryogenesis, cortical interneurons are generated by ventral progenitors located in the ganglionic eminences of the telencephalon. They travel along multiple tangential paths to populate the cortical wall. As they reach this structure they undergo intracortical dispersion to settle in their final destination. At the cellular level, migrating interneurons are highly polarized cells that extend and retract processes using dynamic remodeling of microtubule and actin cytoskeleton. Different levels of molecular regulation contribute to interneuron migration. These include: 1/ Extrinsic guidance cues distributed along migratory streams that are sensed and integrated by migrating interneurons; 2/ Intrinsic genetic programs driven by specific transcription factors that grant specification and set the timing of migration for different subtypes of interneurons; 3/ Adhesion molecules and cytoskeletal elements/regulators that transduce molecular signalings into coherent movement. These levels of molecular regulation must be properly integrated by interneurons to allow their migration in the cortex. The aim of this review is to summarize our current knowledge of the interplay between microenvironmental signals and cell autonomous programs that drive cortical interneuron porduction, tangential migration, and intergration in the developing cerebral cortex. [less ▲]

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See detailImpact of intensive enteral nutrition in association with corticosteroïds in the treatment of severe alcoholic hepatitis: a multicenter randomized controlled trial
Moreno, C; Trepo, E; Louvet, A et al

in Acta Gastro-Enterologica Belgica (2015, March), 78(1), 01

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See detailMulticenter Belgian experience of sofosbuvir (medical need program) in very difficult-to-treat HCV patients: safety and efficacy results.
Degre, D; Laleman, W; Verhelst, X et al

in Acta Gastro-Enterologica Belgica (2015, March), 78(1), 03

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See detailVeno-venous extracorporeal CO2 removal improves pulmonary hemodynamics in a porcine ARDS model
MORIMONT, Philippe ULg; GUIOT, Julien ULg; Desaive, Thomas ULg et al

in Acta Anaesthesiologica Scandinavica (2015)

BACKGROUND: Protective lung ventilation is recommended in patients with acute respiratory distress syndrome (ARDS) to minimize additional injuries to the lung. However, hypercapnic acidosis resulting from ... [more ▼]

BACKGROUND: Protective lung ventilation is recommended in patients with acute respiratory distress syndrome (ARDS) to minimize additional injuries to the lung. However, hypercapnic acidosis resulting from ventilation at lower tidal volume enhances pulmonary hypertension and might induce right ventricular (RV) failure. We investigated if extracorporeal veno-venous CO2 removal therapy could have beneficial effects on pulmonary circulation and RV function. METHODS: This study was performed on an experimental model of ARDS obtained in eight anaesthetized pigs connected to a volume-cycled ventilator. A micromanometer-tipped catheter was inserted into the main pulmonary artery and an admittance micromanometer-tipped catheter was inserted into the right ventricle. RV-arterial coupling was derived from RV pressure-volume loops. ARDS was obtained by repeated bronchoalveolar lavage. Protective ventilation was then achieved, and the pigs were connected to a pump-driven extracorporeal membrane oxygenator (PALP, Maquet, Germany) in order to achieve CO2 removal. RESULTS: ARDS induced severe hypercapnic acidosis. Systolic pulmonary artery pressure significantly increased from 29.6 ± 1.8 to 43.9 ± 2.0 mmHg (P < 0.001). After the PALP was started, acidosis was corrected and normocarbia was maintained despite protective ventilation. Pulmonary artery pressure significantly decreased to 31.6 ± 3.2 mmHg (P < 0.001) and RV-arterial coupling significantly improved (RV-arterial coupling index = 1.03 ± 0.33 vs. 0.55 ± 0.41, P < 0.05). CONCLUSION: Veno-venous CO2 removal therapy enabled protective ventilation while maintaining normocarbia during ARDS. CO2 removal decreased pulmonary hypertension and improved RV function. This technique may be an effective lung- and RV-protective adjunct to mechanical ventilation. [less ▲]

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See detailNumerical crashworthiness analysis of an offshore wind turbine monopile impacted by a ship
Bela, Andreea ULg; Le Sourne, Hervé; Buldgen, Loïc ULg et al

in Shenoi, R Ajit; Soares, Carlos Guedes (Eds.) Analysis and Design of Marine Structures (2015, March)

The consequences of collision events can range from minor structural damages of the supporting structure to complete collapse of the wind turbine, which may lead to disruptions of the electricity ... [more ▼]

The consequences of collision events can range from minor structural damages of the supporting structure to complete collapse of the wind turbine, which may lead to disruptions of the electricity production and, at worst, to sinking of the striking ship with probability of loss of human lives or/and pollution. For all these reasons, a collision risk analysis becomes mandatory at the pre-design stage in order to identify the collision scenarios having the greatest probabilities of occurrence, to estimate the consequences of collision events and to ensure safe operations through the wind farm service life. The goal of this paper is to outline the behavior of the monopile foundations during ship collision by performing non-linear finite element simulations. Many collision scenarios are analyzed in order to study the sensitivity of the monopile to various parameters like impact striking ship velocity, nacelle mass, wind direction, soil stiffness, vertical location of the impact point, wind orientation … The internal energy dissipated by deformation of the monopile, the crushing force and the indentation of the crushed area are compared for different situations, as well as the overall displacements of the supporting structure. [less ▲]

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See detailCharacteriation of GPR101 expression across different species
Trivellin, G; Bjelobaba, I; Daly, Adrian ULg et al

in Abstract book - ENDO 2015 (2015, March)

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See detailX-Linked acro-gigantism (X-LAG) due to microduplications of chromosome Xq26 : A new disorder and implications for acromegaly
Trivellin, G; Daly, AF; Faucz, FR et al

in Abstract book - ENDO 2015 (2015, March)

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See detailL'accoutumance à l'eau: un préalable au savoir-nager.
Mornard, Manhattan ULg; Delvaux, Anne ULg; Cloes, Marc ULg et al

in Éducation Physique et Sport (2015), (364), 16-20

Synthèse de la méthodologie et des travaux scientifiques réalisés au cours de ces dernières années par le cereki dans le domaine de l'accoutumance à l'eau.

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See detailDisease characteristics of patients with X-linked acrogigantism (X-LAG) syndrome
Daly, Adrian ULg; Lodish, MB; Trivellin, G et al

in Abstract book - ENDO 2015 (2015, March)

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See detailAn orphan GPCR may be mutated in patients with Cushing Disease
Correa, RR; Trivellin, G; Li, Y et al

in Abstract book - ENDO 2015 (2015, March)

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See detailPostface aux Nouvelles du Grand Possible et autres récits de Marcel Thiry
Durand, Pascal ULg

in Nouvelles du Grand Possible et autres récits (2015)

Nouvelle édition revue et complétée des Nouvelles du Grand Possible de Marcel Thiry (et seconde édition dans la collection patrimoniale « Espace Nord »). La Postface et les annexes bio-bibliographiques ... [more ▼]

Nouvelle édition revue et complétée des Nouvelles du Grand Possible de Marcel Thiry (et seconde édition dans la collection patrimoniale « Espace Nord »). La Postface et les annexes bio-bibliographiques ont été fortement revues et complétées pour la présente édition, enfin conforme à l'édition originale de l'oeuvre ainsi qu'aux intentions ultérieures de son auteur. [less ▲]

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