Last 7 days
Bookmark and Share    
See detailPolyphosphoesters as a new platform for the design of particulate drug delivery systems
Vanslambrouck, Stéphanie; Ergul Yilmaz, Zeynep; Debuigne, Antoine ULg et al

Conference (2016, June)

Thanks to their biocompatibility and degradability properties, polyphosphates are appealing polymers for biomedical applications. In contrast to aliphatic polyesters, such as poly(ε-caprolactone) and poly ... [more ▼]

Thanks to their biocompatibility and degradability properties, polyphosphates are appealing polymers for biomedical applications. In contrast to aliphatic polyesters, such as poly(ε-caprolactone) and poly(lactide), the pentavalency of the phosphorus atom allows the easy modification of the polyphosphate properties by simply adjusting the nature, the length and the functionality of the polyphosphate pendant groups. Therefore, macromolecular engineering of polyphosphoesters was applied to design well-defined architectures and functionalities adapted to drug nanocarriers. In a first approach, amphiphilic block copolymers are synthesized by organo-catalyzed ring-opening polymerization process for the synthesis of a range of PEO-b-polyphosphate bearing various pendant groups. Post-polymerization thiol-ene click reactions preformed on PEO-b-polyphosphate copolymers was also investigated to improve the hydrophobicity of the polyphosphate. The self-assembly of these PEO-b-polyphosphate copolymers into micelles was investigated, particularly, the effect of the nature of the polyphosphate pendant groups (i) on the micelles characteristics, (ii) on the encapsulation of a poorly soluble drug and (iii) on the drug release profile. The toxicity of the different amphiphilic block copolymers was also evaluated by live/dead cell viability assays. In a second approach, double hydrophilic copolymers based on polyphosphoesters have been used as templating agent for the synthesis of calcium carbonate particles. Indeed, the use of such microparticles is becoming more and more attractive in many fields especially for biomedical applications for which fine tuning of size, morphology and crystalline form of CaCO3 particles is crucial. Although some structuring compounds, like hyaluronic acid, give satisfying results, the control of the particle structure still has to be improved. To this end, we evaluated the CaCO3 structuring capacity of the well-defined double hydrophilic block copolymers composed of poly(ethylene oxide) and of a polyphosphoester segment with affinity for calcium like poly(phosphotriester)s bearing pendant carboxylic acids or poly(phosphodiester)s with a negatively charged oxygen atom on each repeating monomer unit. [less ▲]

Detailed reference viewed: 99 (10 ULg)
Full Text
See detailLa restauration de la collégiale Notre-Dame à Dinant après le sac de 1466
Joly, Emmanuel ULg; Baudry, Antoine

Article for general public (2016)

Partly damaged by fire during the sack of the city of Dinant by Charles the Bold in 1466, the collegiate church of Dinant went through a long and expensive restoration from the year 1472 onwards ... [more ▼]

Partly damaged by fire during the sack of the city of Dinant by Charles the Bold in 1466, the collegiate church of Dinant went through a long and expensive restoration from the year 1472 onwards. Combining the study of the archival evidence with the archaeological analysis of the building itself, this article aims to reassess the extent of this restoration, which had never been studied thoroughly. This paper also seeks to describe the chronology of these operations as well as the building processes at work. [less ▲]

Detailed reference viewed: 18 (0 ULg)
Full Text
See detailLa recherche en Belgique. Transitions. Unité de recherches sur le Moyen Âge tardif & la première Modernité (Université de Liège)
Delfosse, Annick ULg; Henrard, Nadine ULg; Morato, Nicola ULg

in Lettre du Réseau (Réseau des Médiévistes belges de Langue française) (2016), 10

Detailed reference viewed: 22 (1 ULg)
Full Text
Peer Reviewed
See detailCaractérisation des forêts à l’aide de la technologie lidar
Michez, Adrien ULg; Bauwens, Sébastien ULg; Bonnet, Stéphanie ULg et al

in Baghdadi, Nicolas; Zribi, Mehrez (Eds.) Observation des Surfaces Continentales par Télédétection: Agriculture et Forêt (2016)

Detailed reference viewed: 56 (21 ULg)
Full Text
Peer Reviewed
See detailDirect control service from residential heat pump aggregation with specified payback
Georges, Emeline ULg; Cornélusse, Bertrand ULg; Ernst, Damien ULg et al

in Proceedings of the 19th Power Systems Computation Conference (PSCC) (2016, June)

This paper addresses the problem of an aggregator controlling residential heat pumps to offer a direct control flexibility service. The service is defined by a 15 minute power modulation, upward or ... [more ▼]

This paper addresses the problem of an aggregator controlling residential heat pumps to offer a direct control flexibility service. The service is defined by a 15 minute power modulation, upward or downward, followed by a payback of one hour and 15 minutes. The service modulation is relative to an optimized baseline that minimizes the energy costs. The potential amount of modulable power and the payback effect are computed by solving mixed integer linear problems. Within these problems, the building thermal behavior is modeled by an equivalent thermal network made of resistances and lumped capacitances whose parameters are identified from validated models. Simulations are performed on 100 freestanding houses. For an average 4.3 kW heat pump, results show a potential of 1.2 kW upward modulation with a payback of 600 Wh and 150 Wh of overconsumption. A downward modulation of 500 W per house can be achieved with a payback of 420 Wh and 120 Wh of overconsumption. [less ▲]

Detailed reference viewed: 68 (14 ULg)
See detailProbabilistic models of porous materials
Gommes, Cédric ULg

Scientific conference (2016, June)

Detailed reference viewed: 13 (1 ULg)
Peer Reviewed
See detailDetection of myocardial ischemic memory using 99mTc-fucoidan: preclinical validation
Mikail, N; Louedec, L; Aid, R et al

Conference (2016, June)

Detailed reference viewed: 17 (1 ULg)
Full Text
See detailNetwork Theory Framework for Urban Cultural Heritage Conservation
Ginzarly, Manal ULg; Teller, Jacques ULg

Scientific conference (2016, June)

The aim of this study is to propose the application of a network approach to historic urban landscape conservation. Network approaches in landscape ecology and urban studies have been applied in various ... [more ▼]

The aim of this study is to propose the application of a network approach to historic urban landscape conservation. Network approaches in landscape ecology and urban studies have been applied in various ways. In a natural landscape, the ecological network model has been applied to conserve biodiversity. The model consists of core areas, corridors, and buffer zones (Cook & van Lier, 1994; Jongman, 2004).In urban studies, the network metaphor has a long tradition especially in transportation planning. More recently, urban design has brought its contribution by different means. Three of these means are: (i) the space syntax method; (ii) the urban ecological network planning; and (iii) the development of heritage corridors for cultural heritage conservation. As urban landscapes are complex, there have been a multiplicity of methods, and graphical representations to the design of networks. In this context, the application of a network approach to urban cultural heritage conservation poses several questions: what method to use to identify the nodes and links? What kind of attributes to investigate? To answer these questions this study investigates the different types of heritage nodes, and corridors existing in an urban context: cultural, historic, functional, visual, and physical. [less ▲]

Detailed reference viewed: 21 (2 ULg)
Full Text
Peer Reviewed
See detailAir-ice carbon pathways inferred from a sea ice tank experiment
Kotovitch, Marie ULg; Moreau, Sébastien; Zhou, Jiayun et al

in Elementa: Science of the Anthropocene (2016)

Air-ice CO2 fluxes were measured continuously using automated chambers from the initial freezing of a sea ice cover until its decay. Cooling seawater prior to sea ice formation acted as a sink for ... [more ▼]

Air-ice CO2 fluxes were measured continuously using automated chambers from the initial freezing of a sea ice cover until its decay. Cooling seawater prior to sea ice formation acted as a sink for atmospheric CO2, but as soon as the first ice crystals started to form, sea ice turned to a source of CO2, which lasted throughout the whole ice growth phase. Once ice decay was initiated by warming the atmosphere, the sea ice shifted back again to a sink of CO2. Direct measurements of outward ice-atmosphere CO2 fluxes were consistent with the depletion of dissolved inorganic carbon in the upper half of sea ice. Combining measured air-ice CO2 fluxes with the partial pressure of CO2 in sea ice, we determined strongly different gas transfer coefficients of CO2 at the air-ice interface between the growth and the decay phases (from 2.5 to 0.4 mol m−2 d−1 atm−1). A 1D sea ice carbon cycle model including gas physics and carbon biogeochemistry was used in various configurations in order to interpret the observations. All model simulations correctly predicted the sign of the air-ice flux. By contrast, the amplitude of the flux was much more variable between the different simulations. In none of the simulations was the dissolved gas pathway strong enough to explain the large fluxes during ice growth. This pathway weakness is due to an intrinsic limitation of ice-air fluxes of dissolved CO2 by the slow transport of dissolved inorganic carbon in the ice. The best means we found to explain the high air-ice carbon fluxes during ice growth is an intense yet uncertain gas bubble efflux, requiring sufficient bubble nucleation and upwards rise. We therefore call for further investigation of gas bubble nucleation and transport in sea ice. [less ▲]

Detailed reference viewed: 29 (5 ULg)
Full Text
Peer Reviewed
See detailExpliquer la conscience
Rosenthal, David; Dewalque, Arnaud ULg

in Dewalque, Arnaud; Gauvry, Charlotte (Eds.) Conscience et Représentation. Introduction aux théories représentationnelles de l'esprit (2016)

French translation of D. Rosenthal, "Explaining Consciousness", in D. Chalmers (ed.), Philosophy of Mind. Classical and Contemporary Readings, New York, Oxford University Press, 2002, p. 406-421.

Detailed reference viewed: 21 (0 ULg)
Full Text
Peer Reviewed
See detailContext-dependent feature analysis with random forests
Sutera, Antonio ULg; Louppe, Gilles; Huynh-Thu, Vân Anh ULg et al

in Uncertainty In Artificial Intelligence: Proceedings of the Thirty-Two Conference (2016) (2016, June)

Detailed reference viewed: 33 (11 ULg)
Full Text
Peer Reviewed
See detailUn neurinome intra-canalaire lombaire
Manto, Florence; HOUET, Elise ULg; LACREMANS, Pierre ULg et al

in Revue Médicale de Liège (2016), 71(6), 269-271

Detailed reference viewed: 24 (3 ULg)
Full Text
Peer Reviewed
See detailThe scent of love: how important are semiochemicals in the sexual behavior of lady beetles?
Fassotte, Bérénice ULg; Francis, Frédéric ULg; Verheggen, François ULg

in Journal of Pest Science (2016), 89(2), 347-358

Chemical signals are involved in the courtship behavior of many invertebrate and vertebrate species. Lady beetles are no exception to this rule; a significant number of published reports highlight the ... [more ▼]

Chemical signals are involved in the courtship behavior of many invertebrate and vertebrate species. Lady beetles are no exception to this rule; a significant number of published reports highlight the role of cuticular chemicals involved in the reproduction of lady beetles, including gender recognition. Recent data have also demonstrated the presence of a volatile female sex pheromone that facilitates male attraction in some species. Here, we present a synthetic overview of the current knowledge about the sexual behavior of lady beetles and associated chemicals for which the function and identification have been provided. Because lady beetles are often reared as biological control agents, the chemical cues involved in their sexual behavior could be used as components in integrated management approaches against soft-bodied hemipterans. In conclusion, this review provides new perspectives and potential developments for sustainable insect management mainly based on the semiochemicals involved in the sexual behavior of lady beetles. A better understanding of these chemical signals would help maximize their presence in areas where their predatory behavior is requested, as a result of the application of formulations inducing behavioral manipulation. [less ▲]

Detailed reference viewed: 41 (14 ULg)
Full Text
Peer Reviewed
See detailConscience et intentionnalité
Graham, George; Horgan, Terry; Tienson, John et al

in Dewalque, Arnaud; Gauvry, Charlotte (Eds.) Conscience et Représentation. Introduction aux théories représentationnelles de l'esprit (2016)

French translation of G. Graham, T. horgan & J. Tienson, "Consciousness and Intentionality". In M. Velmans et S. Schneider (eds.), The Blackwell Companion to Consciousness, Oxford, Blackwell, 2007, p. 468 ... [more ▼]

French translation of G. Graham, T. horgan & J. Tienson, "Consciousness and Intentionality". In M. Velmans et S. Schneider (eds.), The Blackwell Companion to Consciousness, Oxford, Blackwell, 2007, p. 468-484. [less ▲]

Detailed reference viewed: 15 (2 ULg)
Full Text
Peer Reviewed
See detailPour une théorie dispositionnelle de la pensée d'ordre supérieur
Carruthers, Peter; Dewalque, Arnaud ULg

in Dewalque, Arnaud; Gauvry, Charlotte (Eds.) Conscience et Représentation. Introduction aux théories représentationnelles de l'esprit (2016)

Traduction française du célèbre chapitre de Peter Carruthers, "HOP over FOR, HOT Theory". L'auteur y soutient que les théories représentationnelles de premier ordre (Dretske, Tye, et alii) et les théories ... [more ▼]

Traduction française du célèbre chapitre de Peter Carruthers, "HOP over FOR, HOT Theory". L'auteur y soutient que les théories représentationnelles de premier ordre (Dretske, Tye, et alii) et les théories actualistes de la pensée d'ordre supérieur (e.g., Rosenthal) se heurtent à deux sérieuses difficultés: l'incapacité à rendre compte des concepts d'expérience recognitionnels et l'incapacité à expliquer pourquoi certains états sont phénoménalement conscients et d'autres non. P. Carruthers introduit et défend une théorie alternative, d'après laquelle un état mental est phénoménalement conscient si et seulement s'il est mis à la disposition d'une pensée d'ordre supérieur possible. Cette théorie est baptisée théorie dispositionnelle de la pensée d'ordre supérieur ou "théorie du double contenu". [less ▲]

Detailed reference viewed: 43 (0 ULg)
Full Text
Peer Reviewed
See detailSustaining Inter-Organizational Relationships across Institutional Logics and Power Asymmetries: the Case of Fair Trade
Nicholls, Alex; Huybrechts, Benjamin ULg

in Journal of Business Ethics (2016), 135(4), 699-714

In Fair Trade (FT), as well as in other ‘mixed-form’ fields (Becchetti & Huybrechts 2008; Marwell & McInerney 2005), non-profit organizations and social enterprises have been partnering with large ... [more ▼]

In Fair Trade (FT), as well as in other ‘mixed-form’ fields (Becchetti & Huybrechts 2008; Marwell & McInerney 2005), non-profit organizations and social enterprises have been partnering with large corporations over long time periods despite the presence of conditions that might be expected to destabilize such relationships. These conditions include striking differences in size, economic power, and organizational goals or ‘logics’. Given these asymmetries, the collaborations are typically seen as problematic and temporary because the stronger party (the corporation) will impose its (market) logics upon the weaker one (the social enterprise), leading to either instrumentalizing and corrupting the latter or to the breakdown of the collaboration. Whilst some of the literature on FT and other market-oriented social movements has tended to depict corporate participation as a threat to the original goals of the social movement and to the integrity of partnering social enterprises (e.g. Fridell et al. 2008; Reed 2009), there is evidence of a set of social enterprise-corporate relationships that persist over time and cannot be simply summarized as dominated by the sole corporate, market logic. These examples illustrate the emergence of new working relationships across the conventional divides between distinct sectors – the public, private, and civil society – that offer new approaches to managing power asymmetries and apparently conflicting logics – typically, in FT and more generally in social entrepreneurship, market and social justice/welfare logics (Battilana & Lee 2014; Defourny & Nyssens 2006; Huybrechts & Nicholls 2012; Smith et al. forthcoming). This leads to the following research question: Under what conditions can inter-organizational relationships emerge and be sustained despite power asymmetries and the presence of distinct, potentially conflicting, institutional logics? The analysis in this paper aims to extend theory by providing an alternative to more deterministic analyses of inter-organizational relationships that suggest that the more powerful actor will always impose its logics upon the less powerful organization thus undermining the persistence of the relationship over time. In the process, this research adds a new construct to existing theory around the resolution of conflict in institutional logics by suggesting that dynamic persistence is also evident in contrast to examples of conflict resolution through dominance, compromise, hybridization, synthesis, or relationship breakdown. Based on the analysis of the relationships between commercial buyers and FTOs, initially embodying market and social justice logics respectively, this paper proposes a set of key conditions under which dynamic persistence can be observed even in the presence of power asymmetries. [less ▲]

Detailed reference viewed: 194 (5 ULg)
Full Text
Peer Reviewed
See detailOptical design and optical properties of a VUV spectrographic imager for ICON mission
Loicq, Jerôme ULg; Kintziger, Christian ULg; Mazzoli, Alexandra ULg et al

in Space Telescopes and Instrumentation 2016: Ultraviolet to Gamma Ray (2016, June)

In the frame of the ICON (Ionospheric Connection Explorer) mission of NASA led by UC Berkeley, CSL and SSL Berkeley have designed in cooperation a new Far UV spectro-imager. The instrument is based on a ... [more ▼]

In the frame of the ICON (Ionospheric Connection Explorer) mission of NASA led by UC Berkeley, CSL and SSL Berkeley have designed in cooperation a new Far UV spectro-imager. The instrument is based on a Czerny-Turner spectrograph coupled with two back imagers. The whole field of view covers [± 12° vertical, ± 9° horizontal]. The instrument is surmounted by a rotating mirror to adjust the horizontal field of view pointing by ± 30°. To meet the scientific imaging and spectral requirements the instrument has been optimized. The optimization philosophy and related analysis are presented in the present paper. PSF, distortion map and spectral properties are described. A tolerance study and alignment cases were performed to prove the instrument can be built and aligned. Finally straylight and out of band properties are discussed. [less ▲]

Detailed reference viewed: 15 (4 ULg)
Peer Reviewed
See detailDelivering Bad News to Customers: An Employee Perspective
Delcourt, Cécile ULg; Gremler, Dwayne; Greer, Dominique

Conference (2016, June)

Detailed reference viewed: 32 (4 ULg)