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See detailBreaking Bad News: the TAKE five program
VAN CAUWENBERGE, Isabelle ULg; GILLET, Aline ULg; Bragard, Isabelle ULg et al

Conference (2017, January 14)

Introduction For years, bad news delivery’s impact on patients or their relatives, as well as physicians’ stress has been a major concern. Based on studies claiming the efficacy of training courses to ... [more ▼]

Introduction For years, bad news delivery’s impact on patients or their relatives, as well as physicians’ stress has been a major concern. Based on studies claiming the efficacy of training courses to help physicians delivering such news, many protocols, like SPIKES, BREAKS or SHARE, have emerged worldwide. However, training to such protocol might be time-consuming and not suitable with junior doctors or trainees’ turnover. We hypothesised that a standardized 5-hours training program could improve bad news delivery practice. Participants and methods This preliminary study was conducted in the ED of a tertiary care academic hospital accounting for 90000 ED census per year, 16 attending physicians, 10 junior residents, and 5 trainees per month. Data were collected between November 2015 and April 2016. The study included 3 phases over 4 weeks. Video recorded single role-playing sessions happened the 1st (T1) and the 4th (T3) weeks. A 3-hour theory lesson happened the second week (T2), introducing the basics of therapeutic communication and delivering bad news. Each role-playing session lasted almost 1 hour (10 minutes briefing and medical case reading, 10 minutes role-plays and 40 minutes group debriefing). Bad news delivery performance was evaluated by a 14-points retrospective assessment tool (1). We collected data about the status and impact of a stressful event at 3-days using the French version of the IES-R scale (2). We applied Student t-tests for statistical analysis. Results 14 volunteers (10 trainees and 4 junior emergency physicians) were included in the study. On average, bad-news delivery process took 9’45’’ at T1 and 10’20’’ at T3. From T1 to T3, bad-news delivery performance increased significantly for both junior emergency physicians and trainees (p=0.0003 and p=0.0006, respectively). Further analysis revealed that most relevant increases involved the “situation” (p<0.001), “presentation” (p=0.009), “knowledge” (p=0.037), “emotions” (p=0.01) and “summary” (p=0.001) steps. We also found a significant decrease of the impact of bad-news delivery on trainee physicians’ stress (p=0.006). Discussion and conclusion These preliminary results indicate some potential for this new standardized course of bad news delivery. Apart from allowing physicians increase their communications skills, we believe that this simple 5-hour simulation-training program could alleviate physicians’ stress when they happen to break bad news. References 1. Brunet, A. et al. (2003). Validation of a French version of the Impact of Event Scale-Revised. Can J Psychiatry, 48(1), 56-61. 2. Park, I. et al. (2010). Breaking bad news education for emergency medicine residents: A novel training module using simulation with the SPIKES protocol. J Emerg Trauma Shock, 3(4), 385-388. [less ▲]

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See detailThe added value of plasma or urinary NGAL concentrations in clinical practice
Gregoire, Emilien ULg; Claisse, Guillaume; GUIOT, Julien ULg et al

Poster (2017, January 13)

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See detailMicrobiological load of edible insects found in Belgium
Caparros Megido, Rudy ULg; Desmedt, Sandrine; Blecker, Christophe ULg et al

in Insects (2017)

Edible insects are gaining more and more attention as a sustainable source of animal protein for food and feed in the future. In Belgium, some insect products can be found on the market, and consumers are ... [more ▼]

Edible insects are gaining more and more attention as a sustainable source of animal protein for food and feed in the future. In Belgium, some insect products can be found on the market, and consumers are sourcing fresh insects from fishing stores or towards traditional markets to find exotic insects that are illegal and not sanitarily controlled. From this perspective, this study aims to characterize the microbial load of edible insects found in Belgium (i.e., fresh mealworms and house crickets from European farms and smoked termites and caterpillars from a traditional Congolese market) and to evaluate the efficiency of different processing methods (blanching for all species and freeze-drying and sterilization for European species) in reducing microorganism counts. All untreated insect samples had a total aerobic count higher than the limit for fresh minced meat (6.7 log cfu/g). Nevertheless, a species-dependent blanching step has led to a reduction of the total aerobic count under this limit, except for one caterpillar species. Freeze-drying and sterilization treatments on European species were also effective in reducing the total aerobic count. Yeast and mold counts for untreated insects were above the Good Manufacturing Practice limits for raw meat, but all treatments attained a reduction of these microorganisms under this limit. These results confirmed that fresh insects, but also smoked insects from non-European trades, need a cooking step (at least composed of a first blanching step) before consumption. Therefore, blanching timing for each studied insect species is proposed and discussed. [less ▲]

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See detailRegard juridique sur la fusion des communes : fondements, modalités et mise en œuvre d’une réforme controversée
Bouhon, Frédéric ULg

Conference given outside the academic context (2017)

Cette conférence destinée au grand public visait à exposer les enjeux, les fondements et les implications de la fusion des communes, opérée en Belgique en 1977.

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See detailLandscape ecological consequences of the (sub)urbanization process in an African city: Lubumbashi (Democratic Republic of Congo)
Andre, Marie ULg

Doctoral thesis (2017)

If anthropogenic effect is a general term accounting for the influence of human activities on environment, it may also designate specific influences that may be inter- and intralinked. Thus, urbanization ... [more ▼]

If anthropogenic effect is a general term accounting for the influence of human activities on environment, it may also designate specific influences that may be inter- and intralinked. Thus, urbanization and suburbanization are anthropogenic processes contributing to the broad anthropogenic effect. They hide in turn other subprocesses of land transformation that will be called here the secondary spatial impacts. However, although the growing influence of the latter processes, they are still not defined consensually nor exist a comprehensive and applied-oriented methodology to delimit them. The general objective of this thesis is to develop a spatially explicit methodology to evaluate the landscape ecological consequences of the urbanization and suburbanization processes, taking a representative city of Sub-Saharan Africa as a case study: Lubumbashi (Democratic Republic of Congo), and the last decade as the period of study. That general objective is addressed through two themes, to which correspond specific objectives. The first theme concerns the evaluation of the anthropogenic land use and land cover dynamics and the second one proposes a methodology to evaluate the expansion of urban and suburban areas, in relation with consistent definitions of the areas in the urban-rural gradient. For both themes, the propositions are based on remote sensing techniques and landscape ecology metrics. Results show that the region of Lubumbashi underwent a global anthropisation increase mostly constituted of minor rises of anthropisation levels but impacting mainly the most natural landscape classes. Urban and suburban areas were located through the use of the proportion of built-up metric, the secondary spatial impact area through the use of adjacencies of the less natural landscape patches. The growth shape of the urban and suburban areas is concentric, except in the south-western part of the city where an affluent of the river Kafubu and its adjacent wetlands slow the urban expansion. The secondary spatial impact area dynamics seems determined, in the north-west, by the relief and, in the north-east, by a transportation axis. It is the latter dynamics that is dominant for the period. It corresponds to the so-called savanisation process, probably due to wood fuel and charcoal production. The methodologies developed here could be improved by taking connectedness into account, by using an additional configuration metric for the definition of urban areas or by taking advantage of spatially explicit socio-economic data. They could also be tested on mining sites, other cities and/or using images of different spatial resolution. [less ▲]

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See detailIron, zinc and manganese interaction within the frd3 Arabidopsis mutant
Scheepers, Maxime ULg; Spielmann, Julien ULg; Goormaghtigh, Erik et al

Poster (2017, January 12)

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See detailTracking the Subtle Mutations Thriving Host Sensing by the Plant Pathogen Streptomyces scabies
Deflandre, Benoit ULg; Jourdan, Samuel ULg; Francis, Isolde Maria et al

Poster (2017, January 12)

Le modèle de la pathogénicité végétale chez les Streptomyces, S. scabies est responsable de la maladie de la galle commune. La thaxtomine est la phytotoxine qui cause cette maladie. Il y a peu, la voie de ... [more ▼]

Le modèle de la pathogénicité végétale chez les Streptomyces, S. scabies est responsable de la maladie de la galle commune. La thaxtomine est la phytotoxine qui cause cette maladie. Il y a peu, la voie de production de la toxine a été découverte : celle-ci met en oeuvre un double mécanisme de régulation génétique. Cependant, certains aspects de la perception de son hôte par le pathogène sont toujours inconnus. Dans ce poster, nous proposons plusieurs hypothèses pour expliquer comment quelques éléments subtiles peuvent être à l'origine de ce mécanisme de pathogénicité. [less ▲]

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See detailWhat is the use of shaping a tang? Tool use and hafting of tanged tools in the Aterian of Northern Africa
Tomasso, Sonja ULg; Rots, Veerle ULg

in Archaeological and Anthropological sciences (2017)

We present the results of detailed microscopic examination of tanged tools from the site of Ifri n'Ammar. The rock shelter has a particularly rich and well-preserved stratigraphy that has yielded a large ... [more ▼]

We present the results of detailed microscopic examination of tanged tools from the site of Ifri n'Ammar. The rock shelter has a particularly rich and well-preserved stratigraphy that has yielded a large variety of tanged tools, thus offering a possibility to test hypotheses on the possible links between tangs and hafting. Earlier methodological work has demonstrated that patterned wear forms on the non-active part of the tool as the result of hafted tool use, and that the characteristics of the wear traces depend on the exact hafting arrangement used. In the present study, wear analyses were combined with further experiments that involved the hafting of tanged tools with various materials and arrangements and aimed at understanding the development of this important morphological innovation. We suggest that functional data are needed to understand the relevance of the "Aterian tang" for hafting (or use), and whether this innovation was triggered by functional, cultural or environmental factors. [less ▲]

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See detailAtypical composition and structure of the mitochondrial dimeric ATP synthase from Euglena gracilis
Yadav, K.N. Sathish; Miranda Astudillo, Héctor Vicente ULg; Colina-Tenorio, Lili et al

in Biochimica et Biophysica Acta-Bioenergetics (2017), 1858(4), 267-275

Mitochondrial respiratory-chain complexes from Euglenozoa comprise classical subunits described in other eukaryotes (i.e. mammals and fungi) and subunits that are restricted to Euglenozoa (e.g. Euglena ... [more ▼]

Mitochondrial respiratory-chain complexes from Euglenozoa comprise classical subunits described in other eukaryotes (i.e. mammals and fungi) and subunits that are restricted to Euglenozoa (e.g. Euglena gracilis and Trypanosoma brucei). Here we studied the mitochondrial F1FO-ATP synthase (or Complex V) from the photosynthetic eukaryote E. gracilis in detail. The enzyme was purified by a two-step chromatographic procedure and its subunit composition was resolved by a three-dimensional gel electrophoresis (BN/SDS/SDS). Twenty-two different subunits were identified by mass-spectrometry analyses among which the canonical alpha, beta, gamma, delta, epsilon and OSCP subunits, and at least seven subunits previously found in Trypanosoma. The ADP/ATP carrier was also associated to the ATP synthase into a dimeric ATP synthasome. Single-particle analysis by transmission electron microscopy of the dimeric ATP synthase indicated that the structures of both the catalytic and central rotor parts are conserved while other structural features are original. These new features include a large membrane-spanning region joining the monomers, an external peripheral stalk and a structure that goes through the membrane and reaches the inter membrane space below the c-ring, the latter having not been reported for any mitochondrial F-ATPase. [less ▲]

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See detailLa transformation de la pensée politique dans les Pays-Bas entre xve et xvie siècles
Dumont, Jonathan ULg

Scientific conference (2017, January 11)

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See detailFermi-LAT kills dark matter interpretations of AMS-02 data. Or not?
Belotsky, Konstantin; Budaev, Ruslan; Kirillov, Alexander et al

in Journal of Cosmology and Astroparticle Physics (2017)

A number of papers attempt to explain the positron anomaly in cosmic rays, observed by PAMELA and AMS-02, in terms of dark matter (DM) decays or annihilations. However, the recent progress in cosmic gamma ... [more ▼]

A number of papers attempt to explain the positron anomaly in cosmic rays, observed by PAMELA and AMS-02, in terms of dark matter (DM) decays or annihilations. However, the recent progress in cosmic gamma-ray studies challenges these attempts. Indeed, as we show, any rational DM model explaining the positron anomaly abundantly produces final state radiation and Inverse Compton gamma rays, which inevitably leads to a contradiction with Fermi-LAT isotropic diffuse gamma-ray background measurements. Furthermore, the Fermi-LAT observation of Milky Way dwarf satellites, supposed to be rich in DM, revealed no significant signal in gamma rays. We propose a generic approach in which the major contribution to cosmic rays comes from the dark matter disc and prove that the tension between the DM origin of the positron anomaly and the cosmic gamma-ray observations can be relieved. We consider both a simple model, in which DM decay/annihilate into charged leptons, and a model-independent minimal case of particle production, and we estimate the optimal thickness of DM disk. Possible mechanisms of formation and its properties are briefly discussed. [less ▲]

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See detailPrevalence, location and concurrent diseases of ultrasonographic cyst-like lesions of abdominal lymph nodes in dogs.
Liotta, Annalisa Pia; Billen, Frédéric ULg; Heimann, Marianne et al

in The Veterinary record (2017)

Lymph nodal cyst-like lesions are occasionally identified during abdominal ultrasound in dogs. However, a study evaluating their prevalence and clinical significance is lacking. The aim of this ... [more ▼]

Lymph nodal cyst-like lesions are occasionally identified during abdominal ultrasound in dogs. However, a study evaluating their prevalence and clinical significance is lacking. The aim of this observational cross-sectional study was to evaluate prevalence, most common location and concurrent diseases of cyst-like lymph nodes detected during abdominal ultrasound. Affected lymph nodes, patient signalment and concurrent diseases of dogs with cyst-like lymph nodal lesions having undergone abdominal ultrasound over a one-year period were recorded. Twenty-three affected lymph nodes were observed in 17/553 dogs (prevalence=3 per cent). The most commonly affected was the lumbar lymphocenter (7/23), followed by the coeliac (6/23), the cranial mesenteric (5/23) and the iliosacral (5/23). Twenty-three concurrent diseases were diagnosed in 17 dogs, among which 16/23 were non-neoplastic (70 per cent). The most common concurrent disease was renal insufficiency (8/23), followed by neoplasia (7/23), gastroenteropathy (3/23), benign prostatic disease (2/23), pancreatitis (1/23), peritonitis (1/23) and neurological disease (1/23). No statistical correlation existed between cyst-like lymph nodal lesion and a specific neoplastic or non-neoplastic disease. In conclusion, in the present study, cyst-like lymph nodal lesions have a low prevalence, involve different lymphocenters and were found in dogs affected by different diseases, including both non-neoplastic and neoplastic aetiologies. [less ▲]

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See detailComparison of Micro-objective Nonparametric Statistical Matching Techniques for Integration of Different Survey Data
Eftekhar, Hamed ULg; Cools, Mario ULg

in The Transportation Research Board (TRB) 96th Annual Meeting (2017, January 11)

Lack of information is often reported as one of the main study limitations in transport research. Other data sources provide an important opportunity, as the information from these data sources might be ... [more ▼]

Lack of information is often reported as one of the main study limitations in transport research. Other data sources provide an important opportunity, as the information from these data sources might be fully exploited when they are integrated using an appropriate mathematical framework. This paper determines which data integration techniques can be adopted in the context of road safety, and which criteria should be used to assess the quality of the integrated dataset. The paper contributes to the literature by providing a comparison of different techniques that allow the tabulation of the joint micro-data. To compare the suitability of different Statistical Matching techniques, data from the 2012 Belgium Road Safety Institute (BRSI) Attitude Survey and data from the 2010 Belgian National Household Travel Survey (BELDAM) are integrated. In particular, the socio-economic factor "Income" is being matched to the BRSI Attitude Survey data. The paper discusses and compares different non-parametric micro-objective Statistical Matching techniques, in which the “Income” variable from the BELDAM survey was added to the BRSI Attitude Survey. Based on similarity/dissimilarity measures, the Rank hot-deck Statistical Matching yielded the best result, which is in line with the existing literature. Moreover, from the results, it can be concluded that statistical data matching is a practically applicable technique, which can help overcome the lack of additional information. Further research should focus on using the integrated datasets with an attempt of expanding the scope of variables, and explicitly testing for omitted variable bias. [less ▲]

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