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See detailLa religion des rois des Belges
Bechet, Christophe ULg

Article for general public (2016)

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See detailOn the equivalent static load method for flexible multibody systems described with a nonlinear finite element formalism
Tromme, Emmanuel ULg; Sonneville, Valentin ULg; Bruls, Olivier ULg et al

in International Journal for Numerical Methods in Engineering (2016)

The equivalent static load (ESL) method is a powerful approach to solve dynamic response structural optimization problems. The method transforms the dynamic response optimization into a static response ... [more ▼]

The equivalent static load (ESL) method is a powerful approach to solve dynamic response structural optimization problems. The method transforms the dynamic response optimization into a static response optimization under multiple load cases. The ESL cases are defined based on the transient analysis response whereupon all the standard techniques of static response optimization can be used. In the last decade, the ESL method has been applied to perform the structural optimization of flexible components of mechanical systems modeled as multibody systems (MBS). The ESL evaluation strongly depends on the adopted formulation to describe the MBS and has been initially derived based on a floating frame of reference formulation. In this paper, we propose a method to derive the ESL adapted to a nonlinear finite element approach based on a Lie group formalism for two main reasons. Firstly, the finite element approach is completely general to analyze complex MBS and is suitable to perform more advanced optimization problems like topology optimization. Secondly, the selected Lie group formalism leads to a formulation of the equations of motion in the local frame, that turns out to be a strong practical advantage for the ESL evaluation. Examples are provided to validate the proposed method. [less ▲]

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See detailLe médicament du mois. Insuline glargine 300 U/mL (Toujeo®)
SCHEEN, André ULg

in Revue Médicale de Liège (2016), 71

Summary : This article presents a new formulation of insulin glargine concentrated at 300 U/mL (Gla-300). It is commercialized under the trade name of Toujeo® in an optimized pre-filled SoloStar™ pen for ... [more ▼]

Summary : This article presents a new formulation of insulin glargine concentrated at 300 U/mL (Gla-300). It is commercialized under the trade name of Toujeo® in an optimized pre-filled SoloStar™ pen for the treatment of type 1 and type 2 diabetes in adults. Besides a threefold higher concentration compared to the classical insulin Lantus® (100 U/mL or Gla-100), both pharmacokinetic and pharmacodynamic profiles of Gla-300 are flatter and longer (more than 24 hours) and have a lesser intra-/inter-variability, which makes them more reproducible. Overall, Toujeo® offers the same hypoglycaemic efficacy and the same safety profile when compared with Lantus®. However, a lower risk of hypoglycaemia, especially at night, a slightly smaller weight gain and a better flexibility in the time of injection have been reported. The two insulin formulations are not bioequivalent and the daily insulin requirement is slightly higher with insulin Gla-300 than with insulin Gla-100. The shift from an already available basal insulin towards Toujeo® may require a dose adjustment and a reinforcement of blood glucose monitoring. [less ▲]

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See detailIntroduction
Fallon, Catherine ULg; Aubin, David; Albarello, Luc et al

in Aubin, David; Albarello, Luc; Fallon, Catherine (Eds.) et al Penser l'évaluation des politiques publiques (2016)

Ce livre s’adresse à toutes les personnes qui a des titres divers sont concernés par l’évaluation des politiques publiques parce qu’ils doivent en assurer la réalisation ou en encadrer la démarche. Les ... [more ▼]

Ce livre s’adresse à toutes les personnes qui a des titres divers sont concernés par l’évaluation des politiques publiques parce qu’ils doivent en assurer la réalisation ou en encadrer la démarche. Les exemples et les angles de discussion sont les plus larges possibles pour que le lecteur puisse s’approprier les outils quel que soit son secteur de responsabilité et quel que soit son territoire. Il trouvera dans la suite des chapitres non pas un livre de recettes – ce qui nous semble contraire à la logique d’évaluation de politiques – mais des cadres de réflexion, des propositions de pratiques, ainsi que des références complémentaires pour développer ses pratiques tout en mobilisant un regard critique. [less ▲]

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See detailBalancing benefits and risks of glucocorticoids in rheumatic diseases and other inflammatory joint disorders: new insights from emerging data. An expert consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)
Cooper, C.; Bardin, T.; Brandi, M.L. et al

in Aging Clinical and Experimental Research (2016), 28(1), 1-16

Purpose: This consensus review article considers the question of whether glucocorticoid (GC) therapy is still relevant in the treatment of rheumatic diseases, with a particular focus on rheumatoid ... [more ▼]

Purpose: This consensus review article considers the question of whether glucocorticoid (GC) therapy is still relevant in the treatment of rheumatic diseases, with a particular focus on rheumatoid arthritis (RA), and whether its side effects can be adequately managed. Recent basic and clinical research on the molecular, cellular and clinical effects of GCs have considerably advanced our knowledge in this field. An overview of the subject seems appropriate. Methods: This review is the result of a multidisciplinary expert working group, organised by European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis. The recent literature was surveyed and the salient evidence synthetized. Results: The pathophysiological basis of RA (and other inflammatory rheumatic diseases) now strongly implicates the adaptive immune system in addition to innate mechanisms. The molecular effect of GCs and differential GC sensitivity is better understood, although exploiting this knowledge is still in its infancy. The newer treatment strategies of early and aggressive control of RA have greatly improved clinical outcomes, but improvements are still possible. Newer targeted anti-inflammatory drugs have made an important impact, yet they too are associated with numerous side effects. Discussion: Short durations of moderate doses of GCs are generally well tolerated and have a positive benefit/risk ratio. Patients should be assessed for fracture risk and bone preserving agents and be prescribed calcium and vitamin D supplementation. Conclusions: Within a strategy of a disease modifying approach to inflammatory disease, combination therapy including a GC is effective approach. [less ▲]

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See detailNo favorable effect of reduced tillage on microbial community diversity in a silty loam soil (Belgium)
Degrune, Florine ULg; Theodorakopoulos, Nicolas ULg; Dufrêne, Marc ULg et al

in Agriculture, Ecosystems & Environment (2016)

Among the soil management practices used to promote sustainable agriculture, reduced tillage and retention of residues from the previous crop are reported to enhance significantly both soil fertility and ... [more ▼]

Among the soil management practices used to promote sustainable agriculture, reduced tillage and retention of residues from the previous crop are reported to enhance significantly both soil fertility and crop productivity. Here, high-throughput sequencing (454 technology) was used to see how the tillage regime (conventional vs. reduced tillage) and the fate of crop residues (retention or removal) affect microbial communities at two sampling depths (top soil: 0–5 cm and deeper soil: 15–20 cm) in a fertile silty loam soil in Belgium. All combinations of these three factors were studied. After 6 years of conversion from conventional to reduced tillage, depth emerged as the main factor responsible for variation in microbial diversity, tillage regime ranked second, and finally, crop residue fate had no influence on microbial diversity. For both bacteria and fungi, the diversity appeared higher in the top soil than in the deeper soil, and surprisingly, higher under conventional than under reduced tillage. These differences are explained by changes in community composition due to taxon loss rather than taxon replacement. The specific local set of environmental conditions (a loess-derived soil and an oceanic temperate climate) may explain these results. These observations raise the question: does impoverishment in indicator taxa influence soil processes, and thus crop production? To answer this question, we discuss how the presence of certain indicator taxa liable to play an ecological role might relate to crop productivity. [less ▲]

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See detailLa démarche d'évaluation
Fallon, Catherine ULg; Dethier, Jean Louis

in Albarello, Luc; Aubin, David; Fallon, Catherine (Eds.) et al Penser l'évaluation des politiques publiques (2016)

'évaluation permet aux parties prenantes – parlementaires, administration, partenaires ou simples citoyens – de se forger un jugement sur l'action des pouvoirs publics dont la complexité tend à rendre la ... [more ▼]

'évaluation permet aux parties prenantes – parlementaires, administration, partenaires ou simples citoyens – de se forger un jugement sur l'action des pouvoirs publics dont la complexité tend à rendre la gestion publique de plus en plus opaque. Elle consiste à mesurer les effets propres d'une politique : l’action des pouvoirs publics a-t-elle ou non contribué à atteindre l’objectif fixé, en tout ou partie ? À quel prix ? Des méthodologies ont été développées et expérimentées par des chercheurs spécialisés et la mobilisation de ces méthodes scientifiquement validées permet de professionnaliser et de préciser l’évaluation. Quand une évaluation est menée de façon pluraliste, transparente et reproductible, la discussion publique de ses résultats ne peut qu'améliorer le fonctionnement de notre système démocratique. C’est dans cet effort de compréhension de ce qu’est l’évaluation d’une politique publique que cet ouvrage s’inscri [less ▲]

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See detailL'évaluation des politiques publiques et l'accroissement exponentiel des données
Albarello, Luc; Fallon, Catherine ULg

in Albarello, Luc; Aubin, David; Fallon, Catherine (Eds.) et al Penser l'évaluation des politiques publiques (2016)

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See detailThe new Sfar journals are in place
Plaud, B; Lefrant, JY; BRICHANT, Jean-François ULg

in Current Anaesthesia and Critical Care (2016)

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See detailSome characterizations about Generalized Hölder-Zygmund Spaces Λ_{σ,N}^{α}(R^d)
Kreit, Damien ULg; Nicolay, Samuel ULg

E-print/Working paper (2016)

Generalized Hölder-Zygmund spaces $\Lambda_{\sigma, N}^{\alpha}(\R^{d})$ were recently introduced and are based on a generalization of Besov spaces. Under some conditions, generalized Hölder-Zygmund and ... [more ▼]

Generalized Hölder-Zygmund spaces $\Lambda_{\sigma, N}^{\alpha}(\R^{d})$ were recently introduced and are based on a generalization of Besov spaces. Under some conditions, generalized Hölder-Zygmund and Besov spaces are equal. It has been proved that most properties of classical Hölder-Zygmund spaces are held for spaces $\Lambda^{\sigma,\alpha}(\R^{d})$, which constitute a particular case of spaces $\Lambda_{\sigma, N}^{\alpha}(\R^{d})$ with $N_{j}=2^{j}$. The goal of the present document is to prove that most of these properties are kept for $\Lambda_{\sigma, N}^{\alpha}(\R^{d})$ spaces. [less ▲]

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See detailPlatelet-rich plasma (PRP) to treat chronic patellar tendinopathies: comparison of a single versus two closely-timed injections
Kaux, Jean-François ULg; Libertiaux, Vincent ULg; Croisier, Jean-Louis ULg et al

in Muscles, Ligaments and Tendons Journal (2016), 5(4 (eCollection 2015 Oct-Dec)), 297-298

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See detailThe materials lifecycle : A steering wheel for Europe's Raw Materials Academy.
Pirard, Eric ULg; Greberg, Jenny

in TMS 2016 Supplemental Proceedings (2016, February)

EIT Raw Materials is a major European initiative supported by more than 120 core and associate partners from industry, research and academia. Among the core missions of this network is the establishment ... [more ▼]

EIT Raw Materials is a major European initiative supported by more than 120 core and associate partners from industry, research and academia. Among the core missions of this network is the establishment of a Raw Materials RM Academy to educate T-shaped professionals that will contribute to the development of a sustainable and resource efficient Europe. Every T-shaped professional should combine an in depth knowledge of his own discipline with a sound understanding of the challenges of the full raw materials value chain and with a mindset for innovation and entrepreneurship. The main objective of the RM Academy is to connect all T-shaped professionals to help create the circular economy steering wheel. Therefore, the RM Academy has the following missions: - Label and support educational programs. - Promote a permanent offer of cross-disciplinary programmes, workshops and courses. - Train T-shaped professionals into T-shaped entrepreneurs. - Promote lifelong learning initiatives. - Stimulate wider society learning initiatives aiming at raising social and political awareness. - Closely collaborate with industry - Enable a high degree of mobility of students and professionals [less ▲]

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See detailA 3-year long study of Staphylococcus aureus isolates from subclinical mastitis in three Azawak zebu herds at the Sahelian experimental farm of Toukounous, Niger
Issa Ibrahim, Abdoulkarim; Duprez, Jean-Noël ULg; Bada-alambdeji, Rianatou et al

in Tropical Animal Health and Production (2016), 48(2), 321-329

bovine mastitis. The aim of the present work was to follow in three herds and during the 3 years the clonality of S. aureus isolated from California Mastitis Test (CMT)-positive cows at the experimental ... [more ▼]

bovine mastitis. The aim of the present work was to follow in three herds and during the 3 years the clonality of S. aureus isolated from California Mastitis Test (CMT)-positive cows at the experimental station of Toukounous (Niger) by (i) comparing their pulsed field gel electrophoresis (PFGE) fingerprints, (ii) identifying their virulotypes by PCR amplification and (iii) assessing the production of capsule and the formation of biofilm. The 88 S. aureus isolates belonged to 14 different pulsotypes, 3 of them being predominant: A (30 %), D (27 %), B (15 %). A and B pulsotypes had the highest profile similarity coefficient (94 %), while others had similarity coefficients under 60 %. Seventy-five S. aureus isolates were further studied for their virulotypes, capsular antigens and biofilm production. Most surface factor-, leukocidin- and haemolysin-, but not the enterotoxin-encoding genes were detected in the majority (>75 %) of the isolates and were evenly distributed between the A, B and D pulsotype isolates. The majority of the 72 S. aureus positive with the cap5H or cap8H PCR produced the CP5 (82 %) or the CP8 (88 %) capsular antigen, respectively. Biofilm production by the 57 icaA-positive isolates was strong for 8 isolates, moderate for 31 isolates but weak for 18 isolates, implying that the icaA gene may not be expressed in vitro by one third of the positive isolates. Similar to other studies, those results confirm that a restricted number of S. aureus clones circulate within the three herds at Toukounous and that their specific virulence-associated properties must still be further studied [less ▲]

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See detailEmergency department bed coordination: burden and pitfalls.
GILLET, Aline ULg; Minder, Anaïs ULg; Nyssen, Anne-Sophie ULg et al

Conference (2016, January 30)

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See detailLes Q-codes ; Une table des matières pour la médecine générale
Jamoulle, Marc ULg

Conference (2016, January 30)

Présentaion en français de l'état d'avancement des travaux sur les Q-codes

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See detailIntérêt d'une approche personnalisée de l'HTA
Krzesinski, Jean-Marie ULg

Scientific conference (2016, January 30)

Présentation d'un cas clinique : Attitude thérapeutique chez un hypertendu confirmé NON compliqué, de race noire.

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See detailImportance des différentes formes d'hypertension artérielle en pratique clinique
Krzesinski, Jean-Marie ULg

Scientific conference (2016, January 30)

Définition et classification de la PA en consultation. Prévention de l'HTA et des risques CV. Caractéristiques de l'HTA selon l'âge. Traitement et recommandations ESH 2013.

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