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See detailPhotochemical generation of reactive oxygen species using plasmonic nanoparticles
Lismont, Marjorie ULg

Doctoral thesis (2015)

During his lecture entitled “ There is plenty of room at the bottom ”, Richard Feyn- man foresaw the possibility of manipulating material at the scale of individual atoms and molecules. Although Feynman’s ... [more ▼]

During his lecture entitled “ There is plenty of room at the bottom ”, Richard Feyn- man foresaw the possibility of manipulating material at the scale of individual atoms and molecules. Although Feynman’s conceptual idea of a nanoworld was evoked in 1959, the nanoscience and nanotechnology revolution began 30 years later with the ability to see at the atomic scale with the invention of electronic microscopy and related tools. The size range that has attracted so much attention over these last 30 years is typically from 100 nanometers down to the atomic level. Subsequently, nanomaterials were defined as materials, which have structured components with at least one dimension in this size range. For instance, material with three nanometric dimensions defines a nanoparticle. Among the variety of core materials available to synthesize nanoparticles, noble metal nanoparticles, i.e. gold and silver, have fascinated people for centuries owing to their bright and intense colors, used in particular as decorative pigments in cathedral stained glasses and artworks. The red and yellow colors displayed by gold and silver nanoparti- cles arise from their interaction with light, which one induces collective oscillations of free electrons at the nanoparticle surface in resonance with the light field. This phenomenon is commonly known as the localized surface plasmon resonance. Their remarkable optical properties and the intense electric field generated by plasmonics nanoparticles have brought these nanomaterials in the forefront of nanotechnology research, ranging from photonics to medicine. Shining light on plasmonic nanoparticles to push back limitations of light-activated therapy and so taking part to the societal challenge of cancer treatment improvement defines the global framework of the thesis. Falling within the nanomedicine topic, this one more precisely deals with the development of efficient plasmonic nano-drugs using light to cure diseases. Clearly, nanoplasmonics, which explores how electromagnetic field can be confined over dimension on the order or smaller than the wavelength of light, has come a long way since the stained glass of Roman times. [less ▲]

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See detailPolyphosphate-based amphiphilic copolymers: synthesis and application to drug nanocarriers
Vanslambrouck, Stéphanie ULg

Doctoral thesis (2015)

Thanks to their biocompatibility and degradability properties, polyphosphates are appealing polymers for biomedical applications, especially for drug delivery systems. In contrast to aliphatic polyesters ... [more ▼]

Thanks to their biocompatibility and degradability properties, polyphosphates are appealing polymers for biomedical applications, especially for drug delivery systems. In contrast to aliphatic polyesters, such as poly(?-caprolactone) and poly(lactide), the pentavalency of phosphorus atom allows the easy modification of the polyphosphate properties by simply adjusting the nature, the length and the functionality of the polyphosphate pendants groups. The goal of this thesis focused on the design of drug nanocarriers based on amphiphilic block copolymer micelles well-suited for the encapsulation of poorly soluble drugs. For that purpose, novel diblock copolymers composed of a water-soluble poly(ethylene oxide) block and a polyphosphate block bearing a variety of alkyl side-groups were synthesized. Firstly, n- butyl, i-butyl and n-heptyl cyclic phosphate monomers were synthesized and used for the organo-catalyzed ring-opening polymerization providing a range of PEO-b-polyphosphate amphiphilic copolymers varying by the architecture and length of the polyphosphate pendant group. Then, post-polymerization thiol-ene click reactions on preformed PEO-b- polybutenylphosphate copolymer was used to graft dodecyl or tocopherol side-chains on the polyphosphate block.The micellization of these amphiphilic block copolymers in aqueous medium was then investigated and a comparative study of the encapsulation and release of a poorly soluble model drug, i.e. ketoconazole, was carried out. Ultimately, the synthesis of a triblock copolymer was investigated to prepare shell- crosslinked core-shell-corona micelles to improve the nanoparticles stability. [less ▲]

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See detailThalamic and extrathalamic mechanisms of consciousness after severe brain injury.
Lutkenhoff, Evan; Chiang, Jeffrey; TSHIBANDA, Luaba ULg et al

in Annals of Neurology (2015)

Abstract OBJECTIVE: What mechanisms underlie the loss and recovery of consciousness after severe brain injury? We sought to establish, in the largest cohort of patients with disorders of consciousness ... [more ▼]

Abstract OBJECTIVE: What mechanisms underlie the loss and recovery of consciousness after severe brain injury? We sought to establish, in the largest cohort of patients with disorders of consciousness (DOC) to date, the link between gold standard clinical measures of awareness and wakefulness, and specific patterns of local brain pathology-thereby possibly providing a mechanistic framework for patient diagnosis, prognosis, and treatment development. METHODS: Structural T1-weighted magnetic resonance images were collected, in a continuous sample of 143 severely brain-injured patients with DOC (and 96 volunteers), across 2 tertiary expert centers. Brain atrophy in subcortical regions (bilateral thalamus, basal ganglia, hippocampus, basal forebrain, and brainstem) was assessed across (1) healthy volunteers and patients, (2) clinical entities (eg, vegetative state, minimally conscious state), (3) clinical measures of consciousness (Coma Recovery Scale-Revised), and (4) injury etiology. RESULTS: Compared to volunteers, patients exhibited significant atrophy across all structures (p < 0.05, corrected). Strikingly, we found almost no significant differences across clinical entities. Nonetheless, the clinical measures of awareness and wakefulness upon which differential diagnosis rely were systematically associated with tissue atrophy within thalamic and basal ganglia nuclei, respectively; the basal forebrain was atrophied in proportion to patients' response to sensory stimulation. In addition, nontraumatic injuries exhibited more extensive thalamic atrophy. INTERPRETATION: These findings provide, for the first time, a grounding in pathology for gold standard behavior-based clinical measures of consciousness, and reframe our current models of DOC by stressing the different links tying thalamic mechanisms to willful behavior and extrathalamic mechanisms to behavioral (and electrocortical) arousal. Ann Neurol 2015. [less ▲]

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See detailThe System for Adressing Personal Problems-From medicalisation to Socialisation: Shifts in Belgian Psychiatric and Mental Health Institutions
Thunus, Sophie ULg

Doctoral thesis (2015)

My PhD thesis related the growth of a large social system devoted to the treatment of personal problems; i.e. problems successively labelled as madness, mental illness and mental health problems, from the ... [more ▼]

My PhD thesis related the growth of a large social system devoted to the treatment of personal problems; i.e. problems successively labelled as madness, mental illness and mental health problems, from the early fifties to the present days. That system involved heterogeneous networks of actors, including scientific experts, established professions, social movements, policy makers, services users and international organisations; instruments and knowledge ranging from psychoanalytical theories to biological knowledge and models of governance. It meant to explain how institutional change happened in that complex social system, by studying past and ongoing reforms, considered as interrelated steps towards complete paradigm shift, including shifting policy means, policy objectives and social organisation. By relying on in-depth analyses of five past reforms, it conceptualised the system as composed of interrelated ecologies, corresponding to different kinds of knowledge of personal problems, whose development was directed by protective and expansion strategies used by two coalitions of actors, holding different kinds of resources to influence the change process. The traditional coalition was embedded in the Belgian institutional system; it referred to medical knowledge of personal problems; and held many institutions delivering residential treatments. By contrast, the reformist coalition was connected to international professional and policy networks stimulating change in OECD-mental health systems; it referred to practical knowledge of social psychiatry and evidence produced by international organisations as the World Health Organisation; and it held non-profit associations delivering community treatments. Cross-regulations exerted through joint-participation of those coalitions in successive reforms caused rapid changes in the system’s structural configuration while hindering change in its social organisation. Thus, we suggested thinking of the issue of change in the system as consisting in setting conditions in which the reformist coalition might extensively use its resources in conducting a new reform starting in 2010. By relying on that assumption, I presented three case studies analysing the devising of that reform at the policy level and its implementing through local networks. Those case studies drew attention to the kinds of knowledge used by key actors and to the way in which they used it in joint-attempts to take the leadership of the reform. Three main findings resulted from those case studies. First, the designing of the policy guide framing the reform consisted in assembling different kinds of knowledge together, including policy learning achieved through past changes in the system and knowledge of alternative care models implemented in OECD-countries, in a way that encouraged sustained enactments of knowledge specific to the reformist coalition, while decreasing the relevance of resources specific to the traditional coalition. Second, local meetings caused by the implementing of the reform enabled adaptations of knowledge embodied by the participants, i.e. multiple actors representing different ecologies and members of one of the two coalitions, to enacted knowledge, i.e. knowledge collectively produced by thinking about concrete means to implement the reform locally. Third, enacted knowledge caused, in turn, adaptations of the care model inscribed in the policy guide to local particularities. Those adaptations did not prevent, however, the global philosophy of the new reform, inspired by social psychiatry, from pervading in local networks, among other by being inscribed in operational documents resulting from meetings. Thus, by following the policy guide through local networks where it was translated into concrete practices, I have been able to indicate new directions in the global process of change in the system, towards a complete paradigm shift, from medical to social psychiatry, and to highlight social and learning processes making it possible. [less ▲]

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See detailThermodynamik und Reaktions-Technik am Beispiel PA12
Pfennig, Andreas ULg; Haas, Thomas

Conference (2015, April 18)

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See detailBrazil’s South South Cooperation with Africa : a win win Relationship ? The case of biofuel production in Mozambique
Cusson, Gabrielle ULg

Conference (2015, April 18)

Since Lula’s presidency, South-South development cooperation (SSDC) has been at the heart of Brazil foreign policy priorities. Brazil is now recognized as an emerging actor in international development ... [more ▼]

Since Lula’s presidency, South-South development cooperation (SSDC) has been at the heart of Brazil foreign policy priorities. Brazil is now recognized as an emerging actor in international development cooperation considering its financial investments and the deployment of its many technical cooperation projects. Despite its cooperation in its own region, Brazil mobilizes a considerable amount of resources towards SSDC in Africa, and especially in Portuguese speaking countries, where it develops a “solidarity diplomacy”. Among the many technical cooperation partnerships, two fields of SSDS are considered as priorities for Brazil in Africa; agriculture and biofuels production. Being one of the world most important agricultural producer and exporter and due to the fast growing of its agribusiness industry, Brazil possess a specific expertise he wishes to share with Africa to support its agricultural revolution and to insure its food and energy security. Therefore, Mozambique has been identified as a privileged partner to develop agricultural projects, including biofuels production. Among others, ProSAVANA, a trilateral cooperation project developed in collaboration with Japan, is a very important, but controversial project. Being an emerging country, Brazil has its own strategic, political and commercial interests. Therefore, it is relevant to ask ourselves if an emerging country can deploy a selfless SSDC policy and establish a win win relationship? Is Brazil’s SSDC policy motivated by principles of solidarity or is more of a tool to consolidate its status as a global power? This papers wishes to analyses the real motivations behind Brazil’s SSDC towards Africa. [less ▲]

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See detailLire les textes informatifs au début du secondaire : d’un dispositif didactique à l’étude de l’activité des élèves et à l’accompagnement du travail d’appropriation/transformation des enseignants
De Croix, Séverine ULg; Wyns, Marielle

Conference (2015, April 17)

Notre intervention s’appuie sur les premières données issues d’une recherche de type quasi expérimental , subventionnée par la Fondation Louvain (UCL – Louvain-la-Neuve), qui porte sur l’enseignement ... [more ▼]

Notre intervention s’appuie sur les premières données issues d’une recherche de type quasi expérimental , subventionnée par la Fondation Louvain (UCL – Louvain-la-Neuve), qui porte sur l’enseignement, dans l’ordinaire de la classe, des pratiques de lecture et d’écriture des textes informatifs requises pour réussir à l’école (Bautier et Rayou, 2009 ; Crinon, 2011). « Lirécrire pour apprendre » a pour objectifs (1) d’expérimenter, durant deux années scolaires consécutives, un programme didactique conçu comme une réponse à la prise en charge de difficultés langagières que rencontrent de nombreux élèves face aux usages proprement scolaires des écrits documentaires ; (2) de tester la validité de cet outil auprès d’un échantillon constitué de 90 classes de français du premier degré ( Cèbe & Goigoux, 2007) et (3) d’évaluer les conditions d’implémentation et de mise en œuvre du programme (en termes de formation et d’accompagnement des enseignants) les plus à même de favoriser et de maintenir le changement pédagogique (Rowan & Miller, 2007 ; Dumay, 2009). Dans le cadre de cette communication, nous nous proposons de déplier succinctement les difficultés de lecture et d’écriture identifiées en amont de la conception des cinq modules du programme et de présenter les leviers d’action mobilisés au sein de ceux-ci. Le cœur de la contribution portera ensuite sur l’examen de verbalisations et de traces écrites de l’activité des élèves à l’occasion des deux premiers modules du programme mis en œuvre, intitulés « Se familiariser avec les usages des écrits à visée informative, explicative et justificative » et « Sélectionner des informations dans un ou plusieurs texte(s) et les lier entre elles ». Notre analyse des diverses verbalisations générées par ces modules vise la description qualitative de l’activité des élèves en réaction à l’outil pédagogique que nous introduisons et aux supports et documents qu’ils sont amenés à exploiter. Sera également abordée la question de l’appropriation de l’outil par les enseignants. L’examen des verbalisations produites par ces derniers au cours des séances d’accompagnement (dont bénéficient six équipes partenaires) permettra d’observer les écarts et les lieux de convergence entre, d’une part, les pratiques habituelles des enseignants et, d’autre part, les supports et activités proposés par le programme. Nous verrons dans quelle mesure l’implémentation de l’outil didactique dans les classes amène les enseignants à questionner leurs propres postures, à identifier et à mettre en œuvre des gestes professionnels susceptibles de développer chez l’élève des démarches adaptées à la lecture/écriture de textes informatifs. [less ▲]

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See detailLiposomes entrapping apigenin for the treatment of glioblastoma
Karim, Reatul ULg; Palazzo, Claudio ULg; Dubois, Nadège ULg et al

Poster (2015, April 17)

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See detailFictions du groupe littéraire
Saint-Amand, Denis ULg

Scientific conference (2015, April 17)

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See detailBasement depth and sedimentary infill from deep seismic reflection data at the western tip of the offshore Corinth Rift
Beckers, Arnaud ULg; Tripsanas, Efthymios; Hubert, Aurelia ULg et al

Conference (2015, April 17)

The Corinth rift is a young continental rift located in central Greece. The active part of the rift forms an E-W striking depression – the Gulf of Corinth – that is the deepest in its central part ... [more ▼]

The Corinth rift is a young continental rift located in central Greece. The active part of the rift forms an E-W striking depression – the Gulf of Corinth – that is the deepest in its central part. Extensive seismic surveys have imaged the basin's basement and allowed to estimate the total extension across most of the Gulf except its western tip. Extension is high in the central part and decreases westward and eastward, as reflected in the present-day bathymetry. Two decades of GPS measurements have shown that the extension rate increases westwards from ~5 to 10-15 mm yr-1, but this is not consistent with the long term pattern. However, no data allowed so far to estimate the basement depth at the western tip of the Gulf, where the geodetic extension rate is the largest. Such data would allow to check the apparent inconsistency between the present rate and the long-term estimates of crustal extension. We present here an unpublished multichannel seismic line dating from 1979 and crossing the western tip of the Gulf of Corinth. The line is 22 km long and strikes WNW-ESE, from the Mornos delta to the West-Channel fault. A Maxipulse source has been used, allowing to image the basement below the synrift sedimentary infill. To the east, a ~1.6 km deep basin is imaged between the southern margin of the Gulf and an inactive south-dipping fault located between the Aigion and the Trizonia faults. The sedimentary infill consists in an alternation between basin-focused bodies made of incoherent reflections and more extensive high-amplitude reflectors. Attributing this alternation to eustatic variations give an age of 300-350 ka to the oldest well imaged deposits. Northwest of the Trizonia fault, the basement is imaged at shallower depth, i.e. ~450 m. The western tip of the seismic line reaches the Mornos delta, close to the northern shoreline. There, the depth to the basement is larger, reaching ~1.2 km. The infill is made of 3 units : on the basement lies a thin unit of incoherent reflections that may corresponds to coarse-grained fluvial deposits. A second unit of parallel, high-amplitude, low-frequency reflections could represent deeper-water deposits. The last seismic unit represents the Mornos delta coarse-grained deposits, from 0 to ~0.7 km deep. The depth of the basement deduced from this seismic line at the western tip of the Gulf of Corinth (1.2-1.6 km) is shallower than the one in the central part of the Gulf (2.5-3 km). This reinforce the inconsistency between long-term and short-term rates of extension in the Corinth Rift, which may be explained by assuming that the Western Corinth Rift initiated much later than the Central Rift. These data also allow to constrain the total displacement on the N-dipping Psathopyrgos fault, one of the major, normal, basin-bounding faults at the western tip of the Rift. The total offset would reach 2.1-2.3 km and the uplift/subsidence ratio would be ~1:1.7, implying a slip rate of 2.2-2.5 mm yr-1 based on footwall uplift rate data. [less ▲]

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See detailNarrazioni fluttuanti tra distanziamento e recupero del Paesaggio della Mosa
Occhiuto, Rita ULg

Scientific conference (2015, April 17)

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See detailPinpointing the origin of plastids using phylogenomics
Baurain, Denis ULg

Scientific conference (2015, April 17)

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See detailGlobal, diffuse and direct irradiances modelling over northwestern Europe using regional climate model MAR : validation and construction of a 30-year climatology
Beaumet, Julien ULg; Doutreloup, Sébastien ULg; Fettweis, Xavier ULg et al

Poster (2015, April 17)

Incoming solar global irradiances are modelled using MAR regional climate model forced by ERA-Interim reanalysis. Global irradiances are decomposed into direct and diffuse using sigmoid model from Ruiz ... [more ▼]

Incoming solar global irradiances are modelled using MAR regional climate model forced by ERA-Interim reanalysis. Global irradiances are decomposed into direct and diffuse using sigmoid model from Ruiz-Arias et al. (2010). Results are validated using data from the European Solar Radiation Atlas for Uccle and Braunschweig weather stations. A 30-year climatology has been built and trends and variability have been analyzed. [less ▲]

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See detailTSP model for electric vehicle deliveries, considering speed, loading and path slope.
Bay, Maud ULg; Limbourg, Sabine ULg

Conference (2015, April 17)

In the current Transport White Paper, the European Union presents a roadmap for a more competitive and sustainable European transport system. Concerning Urban Freight Transport, responsible for about a ... [more ▼]

In the current Transport White Paper, the European Union presents a roadmap for a more competitive and sustainable European transport system. Concerning Urban Freight Transport, responsible for about a quarter of CO2 emissions of the transport sector, one of the goals of the EU is to achieve essentially CO2-free city logistics in major urban centres by 2030 by developing and deploying new and sustainable fuels and propulsion systems. The gradual phasing out of ‘conventionally-fuelled’ vehicles from the urban environment contributes to reduce oil dependence, greenhouse gas emissions and local air and noise pollution. To meet European air quality standards, authorities of some major European cities have already introduced Low Emissions Zones where access to urban areas is limited to freight vehicles that meet certain emissions standards. Greater use of low-emission urban trucks based on electric, hydrogen and hybrid technologies would reduce air emissions, but also noise, letting to use road infrastructure more efficiently by making night deliveries and avoiding morning and afternoon peak periods. In addition to their role in the reduction of polluting emissions, the development of low-emission vehicles also allows to mitigate the dependence of the transportation sector to high fossil fuel prices. Electric vehicles have the potential to be powered by renewable energy sources such as wind and solar energy. However, weaknesses can be found in the limited capacity of the battery and the time needed to recharge, and consequently, the limited driving range of electric vehicle. The main sources for final energy consumption are the vehicle size and the engine characteristics, the load factor, the driving pattern, the gradient which represent the average topology of the country, the speed and the acceleration. To maximize the driving range, a routing model, which aims at minimizing the energy consumption, has to be developed. Our paper focus on the Electric Vehicle Traveling Salesman Problem (EV-TSP): given n cities, find the shortest tour, i.e., the shortest directed cycle containing all cities. The classical objective is to minimize the cost tour scheduling to fulfill delivery requests at each location. In this paper we consider the energy cost and we present an extension of the classical problem to minimize the remaining storage capacity of all electric vehicles at the destination node, knowing that there is no recharge operation on the tour. The objective function accounts not just for the travel distance but also on the load of the vehicle and on its speed while the energy consumption of the engine additionally depends on the path to travel, on the slope of the roads and on the vehicle specifications. Moreover, negative consumption that may happen due to regenerative breaking and kinetic energy capture on downhill paths is taken into consideration. Mathematical model is described and computational experiments are performed. [less ▲]

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See detailLes documents administratifs du recto du P.Vat. Gr. 11
Ricciardetto, Antonio ULg

in Amato, Eugenio; Marganne, Marie-Hélène (Eds.) Le traité "Sur l'exil" de Favorinos d'Arles. Papyrologie, philologie et littérature (2015, April 17)

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See detailDiriger un établissement d'accueil de la petite enfance : une question centrale pour le développement d'une qualité des services
Pirard, Florence ULg

Conference given outside the academic context (2015)

Le rôle central des responsables des services d’éducation et d’accueil des jeunes enfants (EAJE) pour le développement d’une qualité de services est souligné dans de nombreux rapports internationaux ... [more ▼]

Le rôle central des responsables des services d’éducation et d’accueil des jeunes enfants (EAJE) pour le développement d’une qualité de services est souligné dans de nombreux rapports internationaux. Citons notamment les travaux de l’OCDE (à paraître), plus particulièrement la partie consacrée au « quality workforce » et à son monitoring. Pourtant, selon les contextes, les contours de ce rôle ne sont pas toujours clairement établis ; ils peuvent être source de confusion et d’ambiguïté. La difficulté de gérer les services en conciliant des fonctions sociales, éducatives et économiques est clairement posée. La difficulté également de gérer une équipe dont les membres ont des statuts parfois précaires, des niveaux de formation disparates dans un cadre budgétaire restreint. Dans ce contexte comment relever le défi d’élaborer et de développer une dynamique de projet éducatif concerté dans tous les services qu’ils soient en collectivité ou à domicile, en milieu urbain ou rural ? Ce problème est clairement posé en Belgique francophone où aucune formation spécifique à l’enfance de niveau supérieur n’est organisée, où aucune expérience utile aux fonctions de direction n’est exigée à ce jour. Une recherche en voie de finalisation (juin 2015) visant à mieux définir les compétences nécessaires aux fonctions d’accueil et d’encadrement des services à l’enfance a permis d’associer une série d’acteurs de l’enfance, de l’enseignement, de la formation et de responsables politico-administratifs. Dans une démarche de recherche-action, il s’est agi de se décentrer des réalités de la Belgique francophone pour comprendre comment les questions se posent aussi dans d’autres contextes européens (France, Flandre, Angleterre, Suède) et ensuite, de prendre des décisions relatives à la redéfinition des référentiels métiers et de formation, à la révision des textes réglementaires pour les services. Tout en évitant de donner des directives universelles qui nieraient les spécificités de contexte, notre intervention propose de relever une série de questions clés relatives aux fonctions de direction, de points de vigilances à relever ainsi que des idées retenues comme essentielles pour l’avenir. [less ▲]

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See detailLe sort des travailleurs non repris en cas de transfert de leur entreprise
Kéfer, Fabienne ULg

Report (2015)

La situation des travailleurs non repris en cas de transfert d’entreprise évolue dans deux directions opposées, selon que le transfert est ou non réalisé sous autorité de justice. La protection des ... [more ▼]

La situation des travailleurs non repris en cas de transfert d’entreprise évolue dans deux directions opposées, selon que le transfert est ou non réalisé sous autorité de justice. La protection des travailleurs non repris en cas d’application de la convention collective n° 32bis est en voie d’extension. Les travailleurs licenciés juste avant la cession sont considérés comme toujours employés par le cédant à la date du transfert de sorte que leur créance est transférée au cessionnaire ; la Cour de cassation n’exige pas que, pour faire valoir ses droits vis-à-vis du cessionnaire, le salarié ait préalablement invité celui-ci à le reprendre à son service. Son arrêt du 29 avril 2013 clarifie la question de la sanction, en reconnaissant que l’ancien article 63 de la loi du 3 juillet 1978 est violé si un ouvrier a été licencié en violation de l’interdiction de licencier prévue l’article 9 de la convention collective n° 32bis, dont les auteurs n’avaient pas précisé la sanction. La similarité entre les concepts de l’article 63 et ceux de la convention collective n° 109 relative à la motivation du licenciement autorisent à penser que cet arrêt facilite aussi la tâche des travailleurs visés par cette dernière lorsqu’ils sont licenciés en violation de l’interdiction de licencier prévue l’article 9 de la convention collective n° 32bis. A l’inverse, les travailleurs non repris dans le cadre d’un transfert sous autorité de justice se trouvent assez démunis. Si la vente est autorisée sans que tous les salariés soient repris, ceux qui ne sont pas transférés conservent pour seul débiteur le cédant qui supportera seul le coût des licenciements alors qu’il est en difficulté financière. Sauf si la Cour de Justice devait un jour avoir l’occasion de décider que la directive 2001/23 est applicable à l’opération, il n’y a pas place ici pour la fiction du transfert des contrats de travail au cessionnaire, et donc le transfert de la créance d’indemnité de rupture. [less ▲]

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See detailLa voix professionnelle
Garnier, Maëva; Remacle, Angélique ULg

Conference given outside the academic context (2015)

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See detailImpact of Aphasia on Consciousness Assessment: A Cross-Sectional Study.
Schnakers, C; Bessou, H; Rubi-Fessen, I et al

in Neurorehabilitation & Neural Repair (2015), 29

BACKGROUND: . Previous findings suggest that language disorders may occur in severely brain-injured patients and could interfere with behavioral assessments of consciousness. However, no study ... [more ▼]

BACKGROUND: . Previous findings suggest that language disorders may occur in severely brain-injured patients and could interfere with behavioral assessments of consciousness. However, no study investigated to what extent language impairment could affect patients' behavioral responses. OBJECTIVE: . To estimate the impact of receptive and/or productive language impairments on consciousness assessment. METHODS: . Twenty-four acute and subacute stroke patients with different types of aphasia (global, n = 11; Broca, n = 4; Wernicke, n = 3; anomic, n = 4; mixed, n = 2) were recruited in neurology and neurosurgery units as well as in rehabilitation centers. The Coma Recovery Scale-Revised (CRS-R) was administered. RESULTS: . We observed that 25% (6 out of 24) of stroke patients with a diagnosis of aphasia and 54% (6 out of 11) of patients with a diagnosis of global aphasia did not reach the maximal CRS-R total score of 23. An underestimation of the consciousness level was observed in 3 patients with global aphasia who could have been misdiagnosed as being in a minimally conscious state, even in the absence of any documented period of coma. More precisely, lower subscores were observed on the communication, motor, oromotor, and arousal subscales. CONCLUSION: . Consciousness assessment may be complicated by the co-occurrence of severe language deficits. This stresses the importance of developing new tools or identifying items in existing scales, which may allow the detection of language impairment in severely brain-injured patients. [less ▲]

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