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See detailRetrieval of Mars' Upper Atmospheric Composition using Dayglow Observations by IUVS on MAVEN
Evans; IUVS team; Stiepen, Arnaud ULg

Poster (2015, December)

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See detailProbing the Martian Atmosphere with MAVEN/IUVS Stellar Occultations
Gröller; IUVS team; Stiepen, Arnaud ULg

Poster (2015, December)

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See detailComparison of serum fractionation methods by data independent label-free proteomics
Baiwir, Dominique ULg; Mazzucchelli, Gabriel ULg; Smargiasso, Nicolas ULg et al

in EuPA Open Proteomics (2015), 9

Off-line sample prefractionations applied prior to biomarker discovery proteomics are options to enable more protein identifications and detect low-abundance proteins. This work compared five commercial ... [more ▼]

Off-line sample prefractionations applied prior to biomarker discovery proteomics are options to enable more protein identifications and detect low-abundance proteins. This work compared five commercial methods efficiency to raw serum analysis using label-free proteomics. The variability of the protein quantities determined for each process was similar to the unprefractionated serum. A 49% increase in protein identifications and 12.2% of reliable quantification were obtained. A 61 times lower limit of protein quantitation was reached compared to protein concentrations observed in raw serum. The concentrations of detected proteins were confronted to estimated reference values. [less ▲]

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See detailSemantic Web and the Future of Health Care Data in Family Practice
Jamoulle, Marc ULg; Vander Stichele, Robert H; Cardillo, Elena et al

in Merit Research Journal of Medicine and Medical Sciences (2015), 3(12), 586-594

Abstract New tools in data management have emerged in the last decade, which are going to revolutionize electronic health records and health information systems. Family practitioners are the first, main ... [more ▼]

Abstract New tools in data management have emerged in the last decade, which are going to revolutionize electronic health records and health information systems. Family practitioners are the first, main and continuous contact with the patient. They are the source and endpoint of the circle of information, generated by judicious medical documentation and smart secondary use of medical data. This article is an introduction to health terminologies, ontologies, semantic data, and linked open data, all expressions used by computer scientists, preparing themselves for the next step: semantic web for health care data [less ▲]

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See detailModeling the dependence between extreme operational losses and economic factors: a conditional semi-parametric Generalized Pareto approach
Hambuckers, julien ULg; Heuchenne, Cédric ULg; Lopez, Olivier

Conference (2015, December)

In this paper, we model the severity distribution of operational losses data, condi- tional on some covariates. Indeed, previous studies [Chernobai et al., 2011, Cope et al., 2012, Chavez-Demoulin et al ... [more ▼]

In this paper, we model the severity distribution of operational losses data, condi- tional on some covariates. Indeed, previous studies [Chernobai et al., 2011, Cope et al., 2012, Chavez-Demoulin et al., 2014a] suggest that this distribution might be in uenced by macroeconomic and rm-speci c factors. We introduce a conditional Generalized Pareto model, where the shape parameter is an unknown function of a linear combina- tion of the covariates. More precisely, we rely on a single-index assumption to perform a dimension reduction that enables to use univariate nonparametric techniques. Hence, we su er neither from too strong parametric assumption nor from the curse of dimen- sionality. Then, we develop an iterative approach to estimate this model, based on the maximisation of a semiparametric likelihood function. Finally, we apply this method- ology on a novel database provided by the bank UniCredit. We use rm-speci c factors to estimate the conditional shape parameter of the severity distribution. Our analysis suggests that the leverage ratio of the company, the proportion of the revenue coming from fees as well as the risk category have an important impact on the tail thickness of this distribution and thus on the probability of su ering from large operational losses. [less ▲]

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See detailThe cultivable surface microbiota of the brown alga Ascophyllum nodosum is enriched in macroalgal-polysaccharide-degrading bacteria
Martin, Marjolaine ULg; Barbeyron, Tristan; Martin, Renée ULg et al

in Frontiers in Microbiology (2015), 6(december),

Bacteriadegradingalgalpolysaccharidesarekeyplayersintheglobalcarboncycleandinalgalbiomassrecycling.Yetthewatercolumn,whichhasbeenstudiedlargelybymetagenomicapproaches,ispoorinsuchbacteriaandtheiralgal ... [more ▼]

Bacteriadegradingalgalpolysaccharidesarekeyplayersintheglobalcarboncycleandinalgalbiomassrecycling.Yetthewatercolumn,whichhasbeenstudiedlargelybymetagenomicapproaches,ispoorinsuchbacteriaandtheiralgal-polysaccharide-degradingenzymes.Evenmoresurprisingly,thefewpublishedstudiesonseaweed-associatedmicrobiomeshaverevealedlowabundancesofsuchbacteriaandtheirspecificenzymes.However,asmacroalgalcell-wallpolysaccharidesdonotaccumulateinnature,thesebacteriaandtheiruniquepolysaccharidasesmustnotbethatuncommon.We,therefore,lookedatthepolysaccharide-degradingactivityofthecultivablebacterialsubpopulationassociatedwithAscophyllumnodosum.FromA.nodosumtriplicates,324bacteriawereisolatedandtaxonomicallyidentified.Outoftheseisolates,78(∼25%)werefoundtoactonatleastonetestedalgalpolysaccharide(agar,i-ork-carrageenan,oralginate).Theisolates“active”onalgal-polysaccharidesbelongto11genera:Cellulophaga,Maribacter,Algibacter,andZobelliaintheclassFlavobacteriia(41)andPseudoalteromonas,Vibrio,Cobetia,Shewanella,Colwellia,Marinomonas,andParaglaceciolaintheclassGammaproteobacteria(37).Amajorpartrepresentslikelynovelspecies.Differentproportionsofbacterialphylaandclasseswereobservedbetweentheisolatedcultivablesubpopulationandthetotalmicrobialcommunitypreviouslyidentifiedonotherbrownalgae.Here,BacteroidetesandGammaproteobacteriawerefoundtobethemostabundantandsomephyla(asPlanctomycetesandCyanobacteria)frequentlyencounteredonbrownalgaeweren’tidentified.Atalowertaxonomiclevel,twelvegenera,well-knowntobeassociatedwithalgae(withtheexceptionforColwellia),wereconsistentlyfoundonallthreeA.nosodumsamples.Evenmoreinteresting,9ofthe11abovementionedgeneracontainingpolysaccharolyticisolateswerepredominantinthiscommoncore.ThecultivablefractionofthebacterialcommunityassociatedwithA.nodosumis,thus,significantlyenrichedinmacroalgal-polysaccharide-degradingbacteriaandthesebacteriaseemimportantfortheseaweedholobionteventhoughtheyareunder-representedinalga-associatedmicrobiomestudies. [less ▲]

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See detailLa vie littéraire au kaléidoscope des Physiologies
Stienon, Valérie ULg

in Site de la Société des Études romantiques et dix-neuviémistes (SERD) (2015)

En mots et en vignettes, la Physiologie littéraire de la monarchie de Juillet élabore ses propres modalités de mise en fiction de la société. Selon un point de vue à la fois avisé et distancié, induit par ... [more ▼]

En mots et en vignettes, la Physiologie littéraire de la monarchie de Juillet élabore ses propres modalités de mise en fiction de la société. Selon un point de vue à la fois avisé et distancié, induit par l’association d’une centralité culturelle parisienne et d’une faible légitimité à l’ombre de la grande littérature, ces petites monographies réorganisent le système des valeurs à travers lesquelles est perçu le fait littéraire à leur époque. C’est l’occasion d’investiguer sur les à-côtés de la littérature, en interrogeant les manières de circonscrire le territoire des lettres et de le faire interagir avec d’autres domaines d’activités. Deux questions font plus particulièrement l’objet de cet article. D'une part, ces textes livrent-ils un traitement englobant et univoque du profil de l’homme de lettres ou s’attachent-ils au contraire à en souligner les nuances et les singularités en multipliant ses variétés, autour de la dichotomie bien connue des figures archétypales du poète et du journaliste ? D'autre part, dans quelle mesure ces textes reconduisent-ils le mythe du génie créateur et les valeurs romantiques du talent et de l’inspiration, compte tenu du fait que celles-ci sont difficilement compatibles avec les stratégies du parvenu et les expédients du jeune auteur pressé d’arriver, ruses que les Physiologies s’appliquent à débusquer, dans la foulée d’une abondante thématisation du macairisme et des fourberies du floueur ? [less ▲]

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See detailExperimental and computational micro–mechanical investigations of compressive properties of polypropylene/multi–walled carbon nanotubes nanocomposite foams
Wan, Fangyi; Tran, Minh Phuong; Leblanc, Christophe ULg et al

in Mechanics of Materials (2015), 91(Part 1), 95-118

The compressive behavior of nanocomposite foams is studied by both experimental and computational micro-mechanics approaches with the aim of providing an efficient computational model for this kind of ... [more ▼]

The compressive behavior of nanocomposite foams is studied by both experimental and computational micro-mechanics approaches with the aim of providing an efficient computational model for this kind of material. The nanocomposites based on polypropylene (PP) and different contents of multi-walled carbon nanotubes (CNTs) are prepared by melt mixing method. The nanocomposite samples are foamed using super-critical carbon dioxide (ScCO2) as blowing agent at different soaking temperatures. The influence of this foaming parameter on the morphological characteristics of the foam micro-structure is discussed. Differential Scanning Calorimetry (DSC) measurements are used to quantify the crystallinity degree of both nanocomposites and foams showing that the crystallinity degree is reduced after the foaming process. This modification leads to mechanical properties of the foam cell walls that are different from the raw nanocomposite PP/CNTs material. Three--point bending tests are performed on the latter to measure the flexural modulus in terms of the crystallinity degree. Uniaxial compression tests are then performed on the foamed samples under quasi-static conditions in order to extract the macro-scale compressive response. Next, a two-level multi-scale approach is developed to model the behavior of the foamed nanocomposite material. On the one hand, the micro-mechanical properties of nanocomposite PP/CNTs cell walls are evaluated from a theoretical homogenization model accounting for the micro-structure of the semi-crystalline PP, for the degree of crystallinity, and for the CNT volume fraction. The applicability of this theoretical model is demonstrated via the comparison with experimental data from the described experimental measurements and from literature. On the other hand, the macroscopic behavior of the foamed material is evaluated using a computational micro-mechanics model using tetrakaidecahedron unit cells and periodic boundary conditions to estimate the homogenized properties. The unit cell is combined with several geometrical imperfections in order to capture the elastic collapse of the foamed material. The numerical results are compared to the experimental measurements and it is shown that the proposed unit cell computational micro-mechanics model can be used to estimate the homogenized behavior, including the linear and plateau regimes, of nanocomposite foams. [less ▲]

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See detailTribulations d’une vieille dame : De la « loi relative aux anormaux et délinquants d’habitude » à la « loi relative à l’internement des personnes atteintes d'un trouble mental »
Garcet, Serge ULg

in Revue Médicale de Liège (2015), 70e année

Le système belge de prise en charge des délinquants atteints de troubles mentaux est organisé selon un principe de défense sociale. Il se caractérise par une double attention pour, d’une part, la ... [more ▼]

Le système belge de prise en charge des délinquants atteints de troubles mentaux est organisé selon un principe de défense sociale. Il se caractérise par une double attention pour, d’une part, la protection de la société par une neutralisation du risque et, d’autre part, la nécessité de soins à prodiguer à la personne internée. L’évolution du cadre juridique de la loi de 1930 relative aux anormaux et délinquants d’habitude à la loi relative à l’internement des personnes atteintes d'un trouble mental de 2014 rend compte des vicissitudes nées du tiraillement entre ces deux piliers sécuritaire et thérapeutique. Dans ce difficile rapport de forces, bien que publiée mais pas encore d’application, la version de 2014 de la loi constitue à bien des égards une évolution positive dans la prise en compte des personnes internées et de leurs besoins. [less ▲]

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See detailIs the O2(a1Δg) Venus nightglow emission controlled by solar activity ?
Soret, Lauriane ULg; Gérard, Jean-Claude ULg

in Icarus (2015), 262

Several past studies showed that the O2(a1Δg) Venus nightglow emission at 1.27 μm is highly variable on a timescale of hours. We examine whether the intensity of this emission shows a more global trend ... [more ▼]

Several past studies showed that the O2(a1Δg) Venus nightglow emission at 1.27 μm is highly variable on a timescale of hours. We examine whether the intensity of this emission shows a more global trend linked to solar activity. [less ▲]

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See detailNIK promotes tissue destruction independently of the alternative NF-kappaB pathway through TNFR1/RIP1-induced apoptosis.
Boutaffala, L.; Bertrand, M. J. M.; Remouchamps, Caroline ULg et al

in Cell death and differentiation (2015)

NF-kappaB-inducing kinase (NIK) is well-known for its role in promoting p100/NF-kappaB2 processing into p52, a process defined as the alternative, or non-canonical, NF-kappaB pathway. Here we reveal an ... [more ▼]

NF-kappaB-inducing kinase (NIK) is well-known for its role in promoting p100/NF-kappaB2 processing into p52, a process defined as the alternative, or non-canonical, NF-kappaB pathway. Here we reveal an unexpected new role of NIK in TNFR1-mediated RIP1-dependent apoptosis, a consequence of TNFR1 activation observed in c-IAP1/2-depleted conditions. We show that NIK stabilization, obtained by activation of the non-death TNFRs Fn14 or LTbetaR, is required for TNFalpha-mediated apoptosis. These apoptotic stimuli trigger the depletion of c-IAP1/2, the phosphorylation of RIP1 and the RIP1 kinase-dependent assembly of the RIP1/FADD/caspase-8 complex. In the absence of NIK, the phosphorylation of RIP1 and the formation of RIP1/FADD/caspase-8 complex are compromised while c-IAP1/2 depletion is unaffected. In vitro kinase assays revealed that recombinant RIP1 is a bona fide substrate of NIK. In vivo, we demonstrated the requirement of NIK pro-death function, but not the processing of its substrate p100 into p52, in a mouse model of TNFR1/LTbetaR-induced thymus involution. In addition, we also highlight a role for NIK in hepatocyte apoptosis in a mouse model of virus-induced TNFR1/RIP1-dependent liver damage. We conclude that NIK not only contributes to lymphoid organogenesis, inflammation and cell survival but also to TNFR1/RIP1-dependent cell death independently of the alternative NF-kappaB pathway.Cell Death and Differentiation advance online publication, 5 June 2015; doi:10.1038/cdd.2015.69. [less ▲]

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See detailHow to Discount Deep Reinforcement Learning: Towards New Dynamic Strategies
François-Lavet, Vincent ULg; Fonteneau, Raphaël ULg; Ernst, Damien ULg

in NIPS 2015 Workshop on Deep Reinforcement Learning (2015, December)

Using deep neural nets as function approximator for reinforcement learning tasks have recently been shown to be very powerful for solving problems approaching real-world complexity. Using these results as ... [more ▼]

Using deep neural nets as function approximator for reinforcement learning tasks have recently been shown to be very powerful for solving problems approaching real-world complexity. Using these results as a benchmark, we discuss the role that the discount factor may play in the quality of the learning process of a deep Q-network (DQN). When the discount factor progressively increases up to its final value, we empirically show that it is possible to significantly reduce the number of learning steps. When used in conjunction with a varying learning rate, we empirically show that it outperforms original DQN on several experiments. We relate this phenomenon with the instabilities of neural networks when they are used in an approximate Dynamic Programming setting. We also describe the possibility to fall within a local optimum during the learning process, thus connecting our discussion with the exploration/exploitation dilemma. [less ▲]

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See detailAccompagner l'implantation de l'approche par compétences en histoire : avec quels moyens d'enseignement ?
Jadoulle, Jean-Louis ULg

in Didactica historica. Revue suisse pour l'enseignement de l'histoire (2015), 1

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See detailEntraîner la communication professionnelle par des dispositifs en e-learning au cours du Master en orthophonie
Martinez Perez, Trecy ULg; Maillart, Christelle ULg; Willems, Sylvie ULg

in Rééducation Orthophonique (2015), 264

La capacité à communiquer efficacement constitue une qualité professionnelle incontournable des orthophonistes. Néanmoins, dans la formation initiale, les compétences communicationnelles sont rarement ... [more ▼]

La capacité à communiquer efficacement constitue une qualité professionnelle incontournable des orthophonistes. Néanmoins, dans la formation initiale, les compétences communicationnelles sont rarement travaillées et évaluées au contraire d’autres compétences cliniques telles que l’évaluation et la rééducation. Beaucoup considèrent en effet que ces compétences relationnelles s’entraîneront naturellement sur le terrain. Or, la communication professionnelle possède des caractéristiques qui lui sont propres et qui doivent être entraînées. Dans le Master en orthophonie à l’Université de Liège, deux dispositifs ont été développés et ciblent la communication au cours de l’entretien anamnestique et de la remise de conclusion. Ces dispositifs reposent essentiellement sur des modules en e-learning et permettent de garantir aux étudiants en orthophonie les bases nécessaires en communication professionnelle avec peu de ressources académiques. [less ▲]

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See detailLe concept de réserve cognitive
Grotz, Catherine ULg; Adam, Stéphane ULg

Conference (2015, November 30)

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See detailLes insectes dans l'agriculture
Hatt, Séverin ULg; Francis, Frédéric ULg

Conference given outside the academic context (2015)

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See detailConcrete Surface Engineering
Courard, Luc ULg; Bissonnette, Benoît; Garbacz, Andrzej

Book published by CRC Press (2015)

The objective of the book is to provide better basic knowledge about concrete surface properties with regard to repair operations. When Long et al. (2001) were asking “Why assess the properties of near-to ... [more ▼]

The objective of the book is to provide better basic knowledge about concrete surface properties with regard to repair operations. When Long et al. (2001) were asking “Why assess the properties of near-to-surface concrete?,” they were referring to bond development, one of the most important research topics in the field of concrete repairs. Adjoining any material to an existing concrete surface intrinsically involves this interfacial issue. Surface engineering is an area of knowledge addressing all surface-related considerations, notably those pertaining to adhesion. It provides a fundamental understanding of what will make the contact effective or not, allowing for interactions of variable intensity between the materials. A variety of suitable scientific tools is available to characterize properties of layer, quality of substrate and adhesion of overlay to substrate. Many of the basics of surface engineering, which has long developed into a discipline in metallurgy, can in fact apply to the repair and surface treatment of concrete, with the main objective of achieving a desired durability. A fundamental approach is presented in this book and explained in connection with a variety of typical concrete repairs and surface treatments. This book is intended to become a leading-edge resource for practicing engineers, architects, repair specialists as well as researchers looking for: • scientific fundamental knowledge needed to understand how a concrete surface may act on adhesion of a variety of systems; • methods and techniques for analysing concrete surface characteristics; • rational means to evaluate advantages and disadvantages of the various surface preparation techniques; • recommendations to ensure satisfactory adherence of repair materials, coatings or injection products to concrete; • guidelines for selecting well adapted repair material and techniques. The authors’ expertise in the field of repair and maintenance of concrete is recognized internationally. They have been involved for many years in the work of related Rilem and ACI workgroups. This book is in fact the result of more than 15 years of collaborative research. [less ▲]

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See detailToward Concessions 2.0 in Central Africa Recognising and managing overlapping tenure rights
Karsenty, Alain; Vermeulen, Cédric ULg

Conference (2015, November 30)

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See detailLa COP21, c'est quoi ?
Ozer, Pierre ULg

Speech/Talk (2015)

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See detailLong-term study of methane and two of its derivatives from solar observations recorded at the Jungfraujoch station
Bader, Whitney ULg

Doctoral thesis (2015)

A long-term study of methane and two of its derivatives, i.e. ethane and methanol from ground-based FTIR solar observations recorded at the high alpine International Scientific Station of the Jungfraujoch ... [more ▼]

A long-term study of methane and two of its derivatives, i.e. ethane and methanol from ground-based FTIR solar observations recorded at the high alpine International Scientific Station of the Jungfraujoch (3580 m a.s.l.) is reported. Those three gases act as tropospheric ozone precursors through their removal pathway and therefore have an impact on air quality. In the stratosphere, methane influences the content of ozone and in the production of water vapor. Moreover, both methane and ethane impact the greenhouse radiative forcing. While the latter is an indirect greenhouse gas because of its sinks, the former is the second most important anthropogenic greenhouse gas after CO2. The primary challenge of this work is the development and optimization of retrieval strategies for the three studied gases from FTIR spectra recorded at the Jungfraujoch station, in the framework of the Network for Detection of Atmospheric Composition Change (NDACC), in order to assess their concentrations in the atmosphere and to study their long-term trend and recent changes as well as their seasonal variations. The development and optimization of a retrieval strategy, based on the selection of the best combination of parameters, aims to limit interferences, minimize residuals, and maximize information content. To this end, the best retrieval strategy has been selected from a great number of available combinations thanks to a method for error analysis developed through this work. A 17-year time series of methanol is presented thanks to the combination of spectral windows for the first time for ground-based observations resulting in the improvement of the information content. We therefore present the first long-term time series of methanol total, lower tropospheric and upper tropospheric–lower stratospheric partial columns. We found no significant long-term trend of methanol but its seasonal cycle shows a high peak-to-peak amplitude of ̴103 % for total columns characterized by minimum values in winter and maximum values during summertime. The presented time series provides a valuable tool for model and satellite validation and complement the few NDACC measurements at northern mid-latitudes. Regarding ethane, we have for the first time included a combination of improved spectroscopic parameters as well as an improved a priori state that substantially reduce fitting residuals and enhance information content. Analysis of the long-term trend of ethane covering 20 years of observations revealed a strong positive trend of ethane from 2009 onwards of ̴5 %/year. We hypothesize that this recent ethane upturn may be the result of a large increase in fugitive emissions from the massive exploitation of shale gas and tight oil reservoirs on the North American continent. Finally, we quantified the changes of methane since 2005 from 10 ground-based NDACC sites, with a mean global increase of 0.30 %/year. Investigations into the source(s) responsible for this re-increase are performed with a GEOS-Chem tagged simulation that provides the contribution of each emission source and one sink to the total methane simulated. From the analysis of the GEOS-Chem tracers on both the local and global scales, we determined that the increasing anthropogenic emissions such as coal mining, gas and oil transport and exploitation, have played a major role in the increase of atmospheric methane observed since 2005 while they are secondary contributors to the total methane budget. [less ▲]

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