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See detailLes enquêtes de terrain du Musée de la Vie wallonne : Un outil au service de la collecte de la mémoire, des savoirs et savoir-faire régionaux
Postula, Jean-Louis ULg

Conference (2016, August 19)

Débutées dans les années 1920, la réalisation de reportages sur le terrain puis la diffusion régulière des résultats de ces recherches ont été pendant longtemps l’un des traits distinctifs de la fonction ... [more ▼]

Débutées dans les années 1920, la réalisation de reportages sur le terrain puis la diffusion régulière des résultats de ces recherches ont été pendant longtemps l’un des traits distinctifs de la fonction scientifique mise en œuvre au Musée de la Vie wallonne. Jusqu’à la fin des années 1980 environ, les activités du Service des enquêtes ont permis au Musée de devenir le conservatoire d’une collection unique en son genre de documents d’archives multimédia – photographies, films et sons. La rénovation du Musée à partir de 2004, assortie de la réorientation de son projet muséal vers le modèle du « musée de société », a été l’occasion d’investir à nouveau du temps et des moyens dans la relance de cette riche tradition d’enquêtes ethnographiques. Grâce à de nombreux exemples, cette communication ambitionne de montrer l’évolution des terrains d’enquêtes du Musée, qui privilégie désormais l’exploration de nouvelles thématiques liées aux enjeux contemporains de nos sociétés urbaines, industrielles et post-industrielles. Oscillant entre continuité et renouvellement, les enquêtes du Musée de la Vie wallonne permettent à l’institution de se profiler comme un contributeur influent à la préservation du patrimoine culturel immatériel de notre région. [less ▲]

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See detailMME mutation in dominant spinocerebellar ataxia with neuropathy (SCA43)
Depondt; Donatello, Simona; Rai, Myriam et al

in Neurology genetics (2016)

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See detailIncorporation of iron and organic matter into young Antarctic sea ice during its initial growth stages
Janssens, Julie; Meiners, Klaus M.; Tison, Jean-Louis et al

in Elementa: Science of the Anthropocene (2016), 4(1), 000123

This study reports concentrations of iron (Fe) and organic matter in young Antarctic pack ice and during its initial growth stages in situ. Although the importance of sea ice as an Fe reservoir for ... [more ▼]

This study reports concentrations of iron (Fe) and organic matter in young Antarctic pack ice and during its initial growth stages in situ. Although the importance of sea ice as an Fe reservoir for oceanic waters of the Southern Ocean has been clearly established, the processes leading to the enrichment of Fe in sea ice have yet to be investigated and quantified. We conducted two in situ sea-ice growth experiments during a winter cruise in the Weddell Sea. Our aim was to improve the understanding of the processes responsible for the accumulation of dissolved Fe (DFe) and particulate Fe (PFe) in sea ice, and of particulate organic carbon and nitrogen, dissolved organic carbon, extracellular polymeric substances, inorganic macro-nutrients (silicic acid, nitrate and nitrite, phosphate and ammonium), chlorophyll a and bacteria. Enrichment indices, calculated for natural young ice and ice newly formed in situ, indicate that during Antarctic winter all of the measured forms of particulate matter were enriched in sea ice compared to underlying seawater, and that enrichment started from the initial stages of sea-ice formation. Some dissolved material (DFe and ammonium) was also enriched in the ice but at lower enrichment indices than the particulate phase, suggesting that size is a key factor for the incorporation of impurities in sea ice. Low chlorophyll a concentrations and the fit of the macro-nutrients (with the exception of ammonium) with their theoretical dilution lines indicated low biological activity in the ice. From these and additional results we conclude that physical processes are the dominant mechanisms leading to the enrichment of DFe, PFe, organic matter and bacteria in young sea ice, and that PFe and DFe are decoupled during sea-ice formation. Our study thus provides unique quantitative insight into the initial incorporation of impurities, in particular DFe and PFe, into Antarctic sea ice. [less ▲]

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See detailCanine idiopathic pulmonary fibrosis : improvement of the phenotype characterization and search for biomarkers and for etiologic agents
Roels, Elodie ULg

Doctoral thesis (2016)

Canine idiopathic pulmonary fibrosis (CIPF) is a progressive parenchymal lung disease of unknown origin, mainly described in old-aged West Highland white terriers (WHWTs). It is characterized by exercise ... [more ▼]

Canine idiopathic pulmonary fibrosis (CIPF) is a progressive parenchymal lung disease of unknown origin, mainly described in old-aged West Highland white terriers (WHWTs). It is characterized by exercise intolerance, cough and dyspnoea/tachypnea with a progressive deterioration until death from respiratory insufficiency. CIPF shares clinical features with human idiopathic pulmonary fibrosis (IPF), while tomodensitometric and histopathological findings do not appear to be exactly the same. Over the past 10 years, several studies have been performed to improve our knowledge about CIPF. However, this disease is still misunderstood and clinicians are dealing with several challenges including the absence of clinical or biological markers for estimating the presence, severity or progression of the disease and related comorbidities such as pulmonary hypertension, the absence of etiologic agent, and the absence of targeted therapy. Consequently, the aims of the present project were (1) to investigate whether high-resolution computed tomography (HRCT) of the lungs obtained under sedation can be used for the diagnosis and for the follow-up of the disease, (2) to study a new echocardiographic parameter for the diagnosis of precapillary pulmonary hypertension induced by CIPF, (3) to study the potential roles of 2 chemokines of interest, CCL2 and CXCL8, as biomarkers of fibrosis and as actors in the pathogenesis of the disease, (4) to determine breed variation of basal blood concentrations of the same chemokines, vascular endothelial growth factor (VEGF), and serotonin, and (5) to search for the presence of herpesvirus as a possible etiologic agent. [less ▲]

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See detailHuman herpesvirus 8-encoded chemokine vCCL2/vMIP-II is an agonist of the atypical chemokine receptor ACKR3/CXCR7
Szpakowska, Martyna; Dupuis, Nadine ULg; Baragli, Alessandra et al

in Biochemical Pharmacology (2016), 114

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See detailDo Agrometeorological Data Improve Optical Satellite-based Estimations of Herbaceous Yield in Sahelian Semi-Arid Ecosystems?
Diouf, Abdoul Aziz ULg; Hiernaux, Pierre; Brandt, Martin et al

in Remote Sensing (2016), 8

Quantitative estimates of forage availability at the end of the growing season in rangelands are helpful for pastoral livestock managers and for local, national and regional stakeholders in natural ... [more ▼]

Quantitative estimates of forage availability at the end of the growing season in rangelands are helpful for pastoral livestock managers and for local, national and regional stakeholders in natural resource management. For this reason, remote sensing data such as the Fraction of Absorbed Photosynthetically Active Radiation (FAPAR) have been widely used to assess Sahelian plant productivity for about 40 years. This study combines traditional FAPAR-based assessments with agrometeorological variables computed by the geospatial water balance program, GeoWRSI, using rainfall and potential evapotranspiration satellite gridded data to estimate the annual herbaceous yield in the semi-arid areas of Senegal. It showed that a machine-learning model combining FAPAR seasonal metrics with various agrometeorological data provided better estimations of the in situ annual herbaceous yield (R² = 0.69; RMSE = 483kg•DM/ha) than models based exclusively on FAPAR metrics (R² = 0.63; RMSE = 550kg•DM/ha) or agrometeorological variables (R² = 0.55; RMSE = 585kg•DM/ha). All the models provided reasonable outputs and showed a decrease in the mean annual yield with increasing latitude, together with an increase in relative inter-annual variation. In particular, the additional use of agrometeorological information mitigated the saturation effects that characterize the plant indices of areas with high plant productivity. In addition, the date of the onset of the growing season derived from smoothed FAPAR seasonal dynamics showed no significant relationship (0.05 p-level) with the annual herbaceous yield across the whole studied area. The date of the onset of rainfall however, was significantly related to the herbaceous yield and its inclusion in fodder biomass models could constitute a significant improvement in forecasting risks of a mass herbaceous deficit at an early stage of the year. [less ▲]

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See detailUlcerative pododermatitis and disseminated erosive lesions associated with cowpox virus infection in a domestic cat
Ludwig, Louisa ULg; Bohn, Jéromine ULg; Remy, Isabelle ULg et al

in Veterinary Record Case Reports (2016)

The authors report on a case of feline cowpox virus infection associated with severe ulcerative dermatitis of a paw and disseminated erosive lesions. While the anamnesis of the cat being a known rodent ... [more ▼]

The authors report on a case of feline cowpox virus infection associated with severe ulcerative dermatitis of a paw and disseminated erosive lesions. While the anamnesis of the cat being a known rodent-hunter, a typical seasonality of infection and the progression of clinical signs from a primary anterior lesion (forelimb) indicated a possible cowpox virus infection, the differential diagnosis was complicated by the resemblance of clinical signs to those induced by feline herpesvirus-dermatitis or feline calicivirus infection. These differential diagnoses were excluded by means of immunostaining and PCR, respectively. Detection of eosinophilic intracytoplasmic inclusion bodies in cells from biopsy material and positive PCR and sequencing results confirmed the diagnosis of cowpox virus infection. Genetic characterisation of the isolate, based on the highly diverse haemagglutinin gene, showed that the strain (Liege 2015; GenBank accession number: KU726584) clustered with other European isolates, mostly from exotic zoo animals. [less ▲]

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See detailCharacterization of stony soils' hydraulic conductivity using laboratory and numerical experiments
Beckers, Eléonore ULg; Pichault, Mathieu; Pansak, Wanwisa et al

in SOIL (2016), 2

Determining soil hydraulic properties is of major concern in various fields of study. Although stony soils are widespread across the globe, most studies deal with gravel-free soils, so that the literature ... [more ▼]

Determining soil hydraulic properties is of major concern in various fields of study. Although stony soils are widespread across the globe, most studies deal with gravel-free soils, so that the literature describing the impact of stones on the hydraulic conductivity of a soil is still rather scarce. Most frequently, models characterizing the saturated hydraulic conductivity of stony soils assume that the only effect of rock fragments is to reduce the volume available for water flow, and therefore they predict a decrease in hydraulic conductivity with an increasing stoniness. The objective of this study is to assess the effect of rock fragments on the saturated and unsaturated hydraulic conductivity. This was done by means of laboratory experiments and numerical simulations involving different amounts and types of coarse fragments. We compared our results with values predicted by the aforementioned predictive models. Our study suggests that it might be ill-founded to consider that stones only reduce the volume available for water flow. We pointed out several factors of the saturated hydraulic conductivity of stony soils that are not considered by these models. On the one hand, the shape and the size of inclusions may substantially affect the hydraulic conductivity. On the other hand, laboratory experiments show that an increasing stone content can counteract and even overcome the effect of a reduced volume in some cases: we observed an increase in saturated hydraulic conductivity with volume of inclusions. These differences are mainly important near to saturation. However, comparison of results from predictive models and our experiments in unsaturated conditions shows that models and data agree on a decrease in hydraulic conductivity with stone content, even though the experimental conditions did not allow testing for stone contents higher than 20 %. [less ▲]

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See detailBiodistribution of Novel 68Ga-Radiolabelled HER2 Aptamers in Mice
Gijs, Marlies; Becker, Guillaume ULg; Plenevaux, Alain ULg et al

in Journal of Nuclear Medicine and Radiation Therapy (2016), 7(5),

Background: Two novel HER2 aptamers were recently selected with great potential for the in vitro diagnosis of HER2-positive cancer. The goal of this study was to examine the in vivo diagnostic potential ... [more ▼]

Background: Two novel HER2 aptamers were recently selected with great potential for the in vitro diagnosis of HER2-positive cancer. The goal of this study was to examine the in vivo diagnostic potential of these HER2 aptamers. Methods: Both HER2 aptamers were radiolabelled with 68Ga, injected in mice bearing a HER2-positive and HER2-negative tumour and evaluated by PET/MRI. Results: Ex vivo bio distribution analysis revealed high uptake in the blood, tissues and organs, except the brain. Interestingly, this high uptake was explained by the slow blood clearance due to non-specific aptamer binding to blood proteins. We observed accumulation of radioactivity in both tumours in time. Although higher uptake in the HER2-positive tumour compared to the HER2-negative tumour was observed, this was accompanied with more necrosis in the HER2-negative tumour, which was observed by 18FDG PET/CT. Conclusion: This work presents a first step towards the development of 68Ga-labelled aptamers for molecular cancer imaging. [less ▲]

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See detailInvestigating the Effect of Plant Root Exudates and of Saponin on Polycyclic Aromatic Hydrocarbons Solubilization in Brownfield Contaminated Soils
Davin, Marie ULg; Fauconnier, Marie-Laure ULg; Colinet, Gilles ULg

Conference (2016, August 08)

In Wallonia, there are 6,000 estimated brownfields (rising to over 3.5 million in Europe) that require remediation. Polycyclic Aromatic Hydrocarbons (PAHs) are a class of recalcitrant carcinogenic ... [more ▼]

In Wallonia, there are 6,000 estimated brownfields (rising to over 3.5 million in Europe) that require remediation. Polycyclic Aromatic Hydrocarbons (PAHs) are a class of recalcitrant carcinogenic/mutagenic organic compounds of major concern as they accumulate in the environment and represent 17% of all encountered pollutants. As an alternative to environmentally aggressive, expensive and often disruptive soil remediation strategies, a lot of research has been directed to developing techniques targeting organic pollutants. The following experiment, based on the observation that PAHs soil content decreases in the presence of plants, aimed at improving our understanding of the underlying mechanisms involved in phytoremediation. It focusses on plant root exudates and whether they improve PAHs solubilization, which would make them more available for bioremediation by soil microorganisms. The effect of saponin, a natural surfactant found in some plant roots such as members of the Fabaceae family, on PAHs solubilization was also investigated as part of the implementation of the experimental protocol. The experiments were conducted on soil collected from a brownfield in Saint-Ghislain (Belgium) and presenting weathered PAHs contamination. Samples of soil were extracted with different solutions containing either plant root exudates or commercial saponin. Extracted PAHs were determined in the different aqueous solutions using High-Performance Liquid Chromatography and Fluorimetric Detection (HPLC-FLD). Both root exudates of alfalfa (Medicago sativa L.) or red clover (Trifoliumpratense L.) and commercial saponin were tested in different concentrations. Distilled water was used as a control. First of all, results show that PAHs are more extracted using saponin solutions than distilled water and that the amounts generally rise with the saponin concentration. However, the amount of each extracted compound diminishes as its molecular weight rises. Also, it appears that passed a certain surfactant concentration, PAHs are less extracted. This suggests that saponin might be investigated as a washing agent in polluted soil remediation techniques, either for ex situ or in situ treatments, as an alternative to synthetic surfactants. On the other hand, preliminary results on experiments using plant root exudates also show differences in PAHs solubilization compared to the control solution. Further results will allow discussion as to whether or not there are differences according to the exudates provenance and concentrations. [less ▲]

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See detailPlaying RPG Maker? Amateur Game Design and Video Gaming
Hurel, Pierre-Yves ULg

Conference (2016, August 04)

Game creation tools like Game Maker or RPG Maker democratize game making and facilitate the development of amateur game design. The best known among these programs have dynamic web-communities with active ... [more ▼]

Game creation tools like Game Maker or RPG Maker democratize game making and facilitate the development of amateur game design. The best known among these programs have dynamic web-communities with active members making thousands of games. However, as of now, there is little research on amateur game design except for modding or education fields. In this paper I argue that approaching amateur game making in these relations with video game playing allows a better understanding of game creation tools’ users. To support my argument, I will lean on the early results of the exploratory step of my ongoing research. [less ▲]

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See detailThe np- Control Charts with the Guaranteed In-Control Performance
Faraz, Alireza ULg; Heuchenne, Cédric ULg

E-print/Working paper (2016)

In this paper, we evaluate the in-control performance of np-control charts with estimated parameters. We then apply the bootstrap method to adjust the control charts’ limits to guarantee the desired in ... [more ▼]

In this paper, we evaluate the in-control performance of np-control charts with estimated parameters. We then apply the bootstrap method to adjust the control charts’ limits to guarantee the desired in-control average run length (ARL0) value in monitoring stage. The adjusted limits ensure that ARL0 would take a value greater than the desired value (say, B) with a certain specified probability, that is Pr⁡(ARL_0>B)=1-ρ. We finally provide users with tables which with practitioners do not need to do bootstrapping Phase I data set to obtain the control limit thresholds. [less ▲]

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See detailThe path to interferometry in space
Rinehart, S. A.; Savini, G.; Holland, W. et al

in Malbet, F.; Creech-Eakman, M.; Tuthill, P. (Eds.) Optical and Infrared Interferometry and Imaging V (2016, August 04)

For over two decades, astronomers have considered the possibilities for interferometry in space. The first of these missions was the Space Interferometry Mission (SIM), but that was followed by missions ... [more ▼]

For over two decades, astronomers have considered the possibilities for interferometry in space. The first of these missions was the Space Interferometry Mission (SIM), but that was followed by missions for studying exoplanets (e.g Terrestrial Planet Finder, Darwin), and then far-infrared interferometers (e.g. the Space Infrared Interferometric Telescope, the Far-Infrared Interferometer). Unfortunately, following the cancellation of SIM, the future for space-based interferometry has been in doubt, and the interferometric community needs to reevaluate the path forward. While interferometers have strong potential for scientific discovery, there are technological developments still needed, and continued maturation of techniques is important for advocacy to the broader astronomical community. We review the status of several concepts for space-based interferometry, and look for possible synergies between missions oriented towards different science goals. [less ▲]

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See detailMaking high-accuracy null depth measurements for the LBTI exozodi survey
Mennesson, Bertrand; Defrere, Denis ULg; Nowak, Matthias et al

in Malbet, F.; Creech-Eakman, M.; Tuthill, P. (Eds.) Optical and Infrared Interferometry and Imaging V (2016, August 04)

The characterization of exozodiacal light emission is both important for the understanding of planetary systems evolution and for the preparation of future space missions aiming to characterize low mass ... [more ▼]

The characterization of exozodiacal light emission is both important for the understanding of planetary systems evolution and for the preparation of future space missions aiming to characterize low mass planets in the habitable zone of nearby main sequence stars. The Large Binocular Telescope Interferometer (LBTI) exozodi survey aims at providing a ten-fold improvement over current state of the art, measuring dust emission levels down to a typical accuracy of 12 zodis per star, for a representative ensemble of 30+ high priority targets. Such measurements promise to yield a final accuracy of about 2 zodis on the median exozodi level of the targets sample. Reaching a 1 σ measurement uncertainty of 12 zodis per star corresponds to measuring interferometric cancellation ("null") levels, i.e visibilities at the few 100 ppm uncertainty level. We discuss here the challenges posed by making such high accuracy mid-infrared visibility measurements from the ground and present the methodology we developed for achieving current best levels of 500 ppm or so. We also discuss current limitations and plans for enhanced exozodi observations over the next few years at LBTI. [less ▲]

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See detailReplacement of Glycoprotein B in Alcelaphine Herpesvirus 1 by Its Ovine Herpesvirus 2 Homolog : Implications in Vaccine Development for Sheep-Associated Malignant Catarrhal Fever.
Cunha, Cristina W.; Taus, Naomi S.; Dewals, Benjamin G ULg et al

in mSphere (2016), 1(4), 00108-16

Vaccine development is a top priority in malignant catarrhal fever (MCF) research. In the case of sheep-associated MCF (SA-MCF) caused by ovine herpesvirus 2 (OvHV-2), progress toward this objective has ... [more ▼]

Vaccine development is a top priority in malignant catarrhal fever (MCF) research. In the case of sheep-associated MCF (SA-MCF) caused by ovine herpesvirus 2 (OvHV-2), progress toward this objective has been hindered by the absence of methods to attenuate or modify the virus, since it cannot be propagated in vitro. As an alternative for vaccine development, in this study, we tested the hypothesis that one of the SA-MCF vaccine candidate targets, OvHV-2 glycoprotein B (gB), could be expressed by a nonpathogenic alcelaphine herpesvirus 1 (AlHV-1) and then evaluated the potential of the AlHV-1/OvHV-2 chimera to be used as a vaccine and a diagnostic tool. The construction and characterization of an AlHV-1/OvHV-2 chimeric virus that is nonpathogenic and expresses an OvHV-2 vaccine target are significant steps toward the development of an SA-MCF vaccine and also provide a valuable means to study OvHV-2 biology. [less ▲]

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See detailAssessment of the sea-ice carbon pump: Insights from a three-dimensional ocean-sea-ice biogeochemical model (NEMO-LIM-PISCES)
Moreau, Sébastien; Vancoppenolle, Martin; Bopp, Laurent et al

in Elementa: Science of the Anthropocene (2016), 4(1), 000122

The role of sea ice in the carbon cycle is minimally represented in current Earth System Models (ESMs). Among potentially important flaws, mentioned by several authors and generally overlooked during ESM ... [more ▼]

The role of sea ice in the carbon cycle is minimally represented in current Earth System Models (ESMs). Among potentially important flaws, mentioned by several authors and generally overlooked during ESM design, is the link between sea-ice growth and melt and oceanic dissolved inorganic carbon (DIC) and total alkalinity (TA). Here we investigate whether this link is indeed an important feature of the marine carbon cycle misrepresented in ESMs. We use an ocean general circulation model (NEMO-LIM-PISCES) with sea-ice and marine carbon cycle components, forced by atmospheric reanalyses, adding a first-order representation of DIC and TA storage and release in/from sea ice. Our results suggest that DIC rejection during sea-ice growth releases several hundred Tg C yr−1 to the surface ocean, of which < 2% is exported to depth, leading to a notable but weak redistribution of DIC towards deep polar basins. Active carbon processes (mainly CaCO3 precipitation but also ice-atmosphere CO2 fluxes and net community production) increasing the TA/DIC ratio in sea-ice modified ocean-atmosphere CO2 fluxes by a few Tg C yr−1 in the sea-ice zone, with specific hemispheric effects: DIC content of the Arctic basin decreased but DIC content of the Southern Ocean increased. For the global ocean, DIC content increased by 4 Tg C yr−1 or 2 Pg C after 500 years of model run. The simulated numbers are generally small compared to the present-day global ocean annual CO2 sink (2.6 ± 0.5 Pg C yr−1 ). However, sea-ice carbon processes seem important at regional scales as they act significantly on DIC redistribution within and outside polar basins. The efficiency of carbon export to depth depends on the representation of surface-subsurface exchanges and their relationship with sea ice, and could differ substantially if a higher resolution or different ocean model were used. [less ▲]

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See detailMemory consolidation in children with Specific Language Impairment: Delayed gains and susceptibility to interference in implicit sequence learning
Desmottes, Lise ULg; Maillart, Christelle ULg; Meulemans, Thierry ULg

in Journal of Clinical and Experimental Neuropsychology (2016)

Introduction: In this study, the time course of the procedural learning of a visuomotor sequence skill was followed over a 24-hour and a 1-week time period in children with and without specific language ... [more ▼]

Introduction: In this study, the time course of the procedural learning of a visuomotor sequence skill was followed over a 24-hour and a 1-week time period in children with and without specific language impairment (SLI). Two aspects of memory consolidation in implicit sequence learning were examined: the evolution of post-training gains in sequence knowledge (Experiment 1) and the susceptibility to interference (Experiment 2). Method and Results: In the first experiment, 18 children with SLI and 17 control children matched for sex, age, and nonverbal intelligence completed a serial reaction-time (SRT) task and were tested 24 hours and 1 week after practicing. The two groups of children attained an equal level of sequence knowledge in the training session, but the children with SLI lacked the consolidation gains displayed by the control children in the two post-training sessions. Working with a new group of children, 17 with SLI and 17 control peers, Experiment 2 examined resistance to interference by introducing a second sequence 15 minutes after the first training session. Similar results were obtained for the performance of both groups in the training session. However, although the performance of the control group improved in the post-training sessions, the performance of the SLI group deteriorated significantly during the consolidation phase due to the interfering sequence. Conclusion: These findings suggest that the consolidation phase of sequence learning is impaired in children with SLI. [less ▲]

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See detailFrom practice-based game research to game design as a cultural technique
Werning, Stefan; Kamp, Michiel; De Smale, Stephanie et al

Conference (2016, August 02)

Panel : de Smale, Stephanie: Game Essays in the Digital Humanities : The paper addresses the use of prototyping for creating game essays, the applicability of game essays within a digital humanities ... [more ▼]

Panel : de Smale, Stephanie: Game Essays in the Digital Humanities : The paper addresses the use of prototyping for creating game essays, the applicability of game essays within a digital humanities framework and the challenges and opportunities of taking a research-centric rather than a player-centric perspective on game design. Kamp, Michiel: Parameters of Musical Interaction in Games : The paper proposes exploring game music by experimenting with the ways in which the soundtrack responds to game states and player interaction beyond adapting analytical techniques borrowed from film music studies, like masking or replacing parts of the soundtrack. Hurel, Pierre-Yves: Amateur Game Design as Reflexive Practice : The paper presents an ethnographic perspective on amateur game design with a particular focus on the use of distinct tools such as RPG Maker and their affordances for reflective practice. Werning, Stefan: From Analytical Play to Analytical Game Design : The paper outlines the transition from intrinsically analytical aspects in (meta-)ludic practices (speed-running, in-game photography, cosplaying, let’s playing etc.) to game design as a cultural technique, i.e. a mode of expression and civic engagement in a gamified society. [less ▲]

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