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See detailFrançois Ier et les artistes du Nord (1515-1547)
Fagnart, Laure ULg

Article for general public (2016)

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See detailLe livre au futur antérieur. Les ambiguïtés d’un motif d’anticipation
Stienon, Valérie ULg; Barel-Moisan, Claire

in Autour de Vallès : Revue de Lectures et d'Etudes Vallésiennes (2016), 45(2015), 147-168

Du tournant du XIXe siècle aux années 1940, le récit d’anticipation est enclin à articuler un imaginaire social et des extrapolations du présent qui le portent à considérer, parmi d’autres aspects ... [more ▼]

Du tournant du XIXe siècle aux années 1940, le récit d’anticipation est enclin à articuler un imaginaire social et des extrapolations du présent qui le portent à considérer, parmi d’autres aspects socioculturels, la situation de la littérature et de ce qu’on peut nommer le modèle culturel « lettré », avec son histoire, ses valeurs, ses acteurs et ses institutions. Sur ce point, on peut observer à la fois la perméabilité des fictions conjecturales aux discours et représentations liés à leur premier contexte, et les modulations originales qu’elles y apportent. [less ▲]

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See detailGrowth partitioning within beech trees (Fagus sylvatica L.) varies in response to summer heat waves and related droughts
Latte, Nicolas ULg; Lebourgeois, François; Claessens, Hugues ULg

in Trees (2016), 30(1), 189-201

To characterize growth partitioning within the tree and its responses to climate, we studied 8 dominant beech trees (Fagus sylvatica L.) of a pure, even-aged 98-year-old stand in Belgium. We sampled 10 ... [more ▼]

To characterize growth partitioning within the tree and its responses to climate, we studied 8 dominant beech trees (Fagus sylvatica L.) of a pure, even-aged 98-year-old stand in Belgium. We sampled 10 disks along the stem from breast height to treetop and examined the inter-annual patterns of, and discrepancies between, ring-area and volume increments by performing detailed stem analysis and dendroecological investigations. Although the common inter-annual variation among all increment series was high, we observed increasing growth variability and climate sensitivity with height, leading to notable bole-crown discrepancies. Both the common inter-annual variation and bole-crown discrepancies were mainly driven by summer heat waves and related droughts of the previous year, and spring droughts of the current year. Despite these discrepancies, the radial growth at breast height can be considered a good estimate of the tree volume increment but not for the purpose of focusing on climatic effects of isolated years. Extreme climatic conditions increase the risk of inaccurate estimations. The results of the present study are discussed in relation to tree ecophysiology hypotheses. [less ▲]

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See detailPratiques de détournement du jeu vidéo
Barnabé, Fanny ULg

Scientific conference (2016, February)

Séance de cours sur les différentes pratiques de détournement du jeu vidéo par les joueurs (fanfictions, machinimas, speedrun, modding,...).

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See detailConséquences génétiques et morphologiques des glaciations du Quaternaire : une lignée relique du barbeau (Luciobarbus pallaryi, Cyprinidae) dans le bassin du Guir (Algerie)
Brahimi, Amina; Tarai, Nacer; Benhassane, Abdelkrim et al

in Comptes Rendus Biologies (2016), 339

Climatic variations during the Quaternary period had a considerable impact on landscapes and habitat fragmentation (rivers) in North Africa. These historical events can have significant consequences on ... [more ▼]

Climatic variations during the Quaternary period had a considerable impact on landscapes and habitat fragmentation (rivers) in North Africa. These historical events can have significant consequences on the genetic structure of the populations. Indeed, geographi- cally separated and genetically isolated populations tend to differentiate themselves through time, eventually becoming distinct lineages, allowing new species to emerge in later generations. The aim of the present study is to use genetic and morphological techniques to evaluate the major role of the Saalian glaciation (Middle Quaternary) in the establishment of the geographic space and in the evolution of the intraspecific genetic diversity, by tracing the demographic history of barbels belonging to the Luciobarbus pallaryi (Cyprinidae) species in the Guir Basin (Algeria). In this context, two populations, from two distinct and isolated sites, were studied. Analysis of the cytochrome b (cyt b) mitochondrial markers and of the ‘‘D-loop’’ control region has shown that the ‘‘upstream’’ and ‘‘downstream’’ Guir populations are genetically differentiated. The molecular analyses suggest that the upstream population was disconnected from this hydrographic system during the Saalian glaciation period of the Quaternary. Subsequently, it was isolated in the foggaras underground waters in the Great Western Erg, at approximately 320 000 years BP, creating, through a bottleneck effect, a new allopatric lineage referred to as ‘‘Adrar’’. Conversely, the high genetic diversity in the upstream Guir (Bechar) population suggests that the stock is globally in expansion. These barbels (n = 52) were also examined with meristic, morphometric, osteological, and biological features [less ▲]

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See detailDynamics of Internalization and Recycling of the Pro-Metastatic Membrane Type 4-Matrix Metalloproteinase (MT4-MMP) in Breast Cancer Cells
Truong, Alice ULg; Yip, Cassandre ULg; PAYE, Alexandra ULg et al

in FEBS Journal (2016), 283(4), 704-22

MT4-MMP (MMP17) is a glycosylphosphatidyl inositol (GPI)-anchored membrane-type MMP expressed on the cell surface of human breast cancer cells. In triple negative breast cancer cells, MT4-MMP promotes ... [more ▼]

MT4-MMP (MMP17) is a glycosylphosphatidyl inositol (GPI)-anchored membrane-type MMP expressed on the cell surface of human breast cancer cells. In triple negative breast cancer cells, MT4-MMP promotes primary tumor growth and lung metastases. Although trafficking and internalization of the transmembrane MT1-MMP have been extensively investigated, little is known about the regulatory mechanisms of the GPI-anchored MT4-MMP. Here, we investigated the fate and cellular trafficking of MT4-MMP by analyzing its homophilic complex interactions, internalization and recycling dynamics compared to an inert form, MT4-MMP-E249A. Oligomeric and dimeric complexes were analyzed by co-transfection of cells with FLAG- or Myc-tagged MT4-MMP by reducing and non-reducing immunoblots and co-immunoprecipitation experiments. The trafficking of MT4-MMP was studied using an antibody feeding assay and confocal microscopy analysis or cell surface protein biotinylation and Western blot analysis. We demonstrate that MT4-MMP forms homophilic complexes at the cell surface, internalizes in early endosomes, and some of the enzyme is either auto-degraded or recycled to the cell surface. Our data indicate that MT4-MMP is internalized by the CLIC/GEEC pathway, a mechanism that differs from other MT-MMP members. Although MT4-MMP localizes with caveolin-1, MT4-MMP internalization was not affected by inhibitors of caveolin-1 or clathrin endocytosis pathways but was reduced by cdc42 or RhoA silencing with siRNA. We provide a new mechanistic insight into the regulatory mechanisms of MT4-MMP, which may have implications in the design of novel therapeutic strategies for metastatic breast cancer. This article is protected by copyright. All rights reserved. [less ▲]

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See detailCoeur de crèche
Courtejoie, Fabienne ULg

in A+ Architecture en Belgique (2016), 258

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See detailCOMMENT J'EXPLORE... LA BIPOLARITE EN PEDOPSYCHIATRIE : UNE SEMIOLOGIE DIMENSIONNELLE
SCHOLL, Jean-Marc ULg

in Revue Médicale de Liège (2016), 71(2), 94-100

Despite its high frequency, bipolarity in childhood is little understood and is often diagnosed only after several years of development, and this during a time when the child’s psychosocial future is at ... [more ▼]

Despite its high frequency, bipolarity in childhood is little understood and is often diagnosed only after several years of development, and this during a time when the child’s psychosocial future is at stake. A proper diagnosis requires recognition of accurate clinical signs. It is therefore essential to furnish clinicians with precise semiological markers. This paper presents a dimensional semiology for use in anamnesis and in clinical observation of the child. These clinical signs enable the identification of a bipolar manic temperament in the child and/or the identification of various different forms of childhood bipolar and depressive disorder. The relevant differential diagnoses and comorbidities are also presented. [less ▲]

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See detailSciaenops ocellatus: Daily and seasonal sound variation during spawning in aquaculture.
Henry, Séverine ULg; Falguière, Jean Claude; Devillers, Samson et al

Poster (2016, February)

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See detailMaster equation for collective spontaneous emission with quantized atomic motion
Damanet, François ULg; Braun, Daniel; Martin, John ULg

in Physical Review A (2016), 93

We derive a Markovian master equation for the internal dynamics of an ensemble of two-level atoms including all effects related to the quantization of their motion. Our equation provides a unifying ... [more ▼]

We derive a Markovian master equation for the internal dynamics of an ensemble of two-level atoms including all effects related to the quantization of their motion. Our equation provides a unifying picture of the consequences of recoil and indistinguishability of atoms beyond the Lamb-Dicke regime on both their dissipative and conservative dynamics, and applies equally well to distinguishable and indistinguishable atoms. We give general expressions for the decay rates and the dipole-dipole shifts for any motional states, and we find closed-form formulas for a number of relevant states (Gaussian states, Fock states, and thermal states). In particular, we show that dipole-dipole interactions and cooperative photon emission can be modulated through the external state of motion. [less ▲]

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See detailThéorie critique de l'information - Corpus de Presse
Geuens, Geoffrey ULg

Learning material (2016)

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See detailDiacerein: Benefits, Risks and Place in the Management of Osteoarthritis. An Opinion-Based Report from the ESCEO
Pavelka, Karel; Bruyère, Olivier ULg; Cooper, Cyrus et al

in Drugs & Aging (2016), 33(2), 75-85

Diacerein is a symptomatic slow-acting drug in osteoarthritis (SYSADOA) with anti-inflammatory, anti-catabolic and pro-anabolic properties on cartilage and synovial membrane. It has also recently been ... [more ▼]

Diacerein is a symptomatic slow-acting drug in osteoarthritis (SYSADOA) with anti-inflammatory, anti-catabolic and pro-anabolic properties on cartilage and synovial membrane. It has also recently been shown to have protective effects against subchondral bone remodelling. Following the end of the revision procedure by the Pharmacovigilance Risk Assessment Committee of the European Medicines Agency, the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) constituted a panel of 11 experts to better define the real place of diacerein in the armamentarium for treating OA. Based on a literature review of clinical trials and meta-analyses, the ESCEO confirms that the efficacy of diacerein is similar to that of non-steroidal anti-inflammatory drugs (NSAIDs) after the first month of treatment, and superior to that of paracetamol. Additionally, diacerein has shown a prolonged effect on symptoms of several months once treatment was stopped. The use of diacerein is associated with common gastrointestinal disorders such as soft stools and diarrhoea, common mild skin reactions, and, uncommonly, hepatobiliary disorders. However, NSAIDs and paracetamol are known to cause potentially severe hepatic, gastrointestinal, renal, cutaneous and cardiovascular reactions. Therefore, the ESCEO concludes that the benefit–risk balance of diacerein remains positive in the symptomatic treatment of hip and knee osteoarthritis. Furthermore, similarly to other SYSADOAs, the ESCEO positions diacerein as a first-line pharmacological background treatment of osteoarthritis, particularly for patients in whom NSAIDs or paracetamol are contraindicated [less ▲]

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See detailLe droit européen des successions Commentaire du Règlement n°650/2012 du 4 juillet 2012
Wautelet, Patrick ULg; Bonomi, Andrea

Book published by Larcier (2016)

Cet ouvrage constitue un guide pour comprendre et utiliser le droit international privé européen des successions. Il contient un commentaire de l'ensemble des dispositions européennes, à la lumière du ... [more ▼]

Cet ouvrage constitue un guide pour comprendre et utiliser le droit international privé européen des successions. Il contient un commentaire de l'ensemble des dispositions européennes, à la lumière du droit international privé comparé et des questions qu'ont pu faire apparaître les premières applications du Règlement. [less ▲]

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See detailMapping of riparian invasive species with supervised classification of Unmanned Aerial System (UAS) imagery
Michez, Adrien ULg; Piégay, Hervé; Lisein, Jonathan ULg et al

in International Journal of Applied Earth Observation and Geoinformation (2016), 44

Riparian zones are key landscape features, representing the interface between terrestrial and aquatic ecosystems. Although they have been influenced by human activities for centuries, their degradation ... [more ▼]

Riparian zones are key landscape features, representing the interface between terrestrial and aquatic ecosystems. Although they have been influenced by human activities for centuries, their degradation has increased during the 20th century. Concomitant with (or as consequences of) these disturbances, the invasion of exotic species has increased throughout the world’s riparian zones. In our study, we propose a easily reproducible methodological framework to map three riparian invasive taxa using Unmanned Aerial Systems (UAS) imagery: Impatiens glandulifera Royle, Heracleum mantegazzianum Sommier and Levier, and Japanese knotweed (Fallopia sachalinensis (F. Schmidt Petrop.), Fallopia japonica (Houtt.) and hybrids). Based on visible and near-infrared UAS orthophoto, we derived simple spectral and texture image metrics computed at various scales of image segmentation (10,30, 45, 60 using eCognition software). Supervised classification based on the random forests algorithm was used to identify the most relevant variable (or combination of variables) derived from UAS imagery for mapping riparian invasive plant species. The models were built using 20% of the dataset, the rest of the dataset being used as a test set (80%). Except for H. mantegazzianum, the best results in terms of global accuracy were achieved with the finest scale of analysis (segmentation scale parameter = 10). The best values of overall accuracies reached 72%, 68%, and 97% for I. glandulifera, Japanese knotweed, and H. mantegazzianum respectively. In terms of selected metrics, simple spectral metrics (layer mean / camera brightness) were the most used. Our results also confirm the added value of texture metrics (GLCM derivatives) for mapping riparian invasive species. The results obtained for I. glandulifera and Japanese knotweed do not reach sufficient accuracies for operational applications. However, the results achieved for H. mantegazzianum are encouraging. The high accuracies values combined to relatively light model-inputs needed (delineation of a few umbels) make our approach a serious contender as a cost-effective tool to improve the field management of H. mantegazzianum. [less ▲]

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See detailL'arrêt de mort des (trop) petites circonscriptions électorales wallonnes
Bouhon, Frédéric ULg

in Journal des Tribunaux (2016), 6634

Cet article propose un commentaire de l'arrêt n° 169/2015 de la Cour constitutionnelle belge, par lequel elle a considéré que les règles législatives qui instaurent les plus petites circonscriptions ... [more ▼]

Cet article propose un commentaire de l'arrêt n° 169/2015 de la Cour constitutionnelle belge, par lequel elle a considéré que les règles législatives qui instaurent les plus petites circonscriptions utilisées pour les élections du Parlement wallon sont inconstitutionnelles. L'article revient sur les enjeux du découpage du territoire en circonscriptions électorales, sur la jurisprudence antérieure en la matière et suggère un certain nombre d'adaptations que le législateur wallon pourrait adopter pour réagir à l'arrêt. [less ▲]

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See detailOn the equivalent static load method for flexible multibody systems described with a nonlinear finite element formalism
Tromme, Emmanuel ULg; Sonneville, Valentin ULg; Bruls, Olivier ULg et al

in International Journal for Numerical Methods in Engineering (2016)

The equivalent static load (ESL) method is a powerful approach to solve dynamic response structural optimization problems. The method transforms the dynamic response optimization into a static response ... [more ▼]

The equivalent static load (ESL) method is a powerful approach to solve dynamic response structural optimization problems. The method transforms the dynamic response optimization into a static response optimization under multiple load cases. The ESL cases are defined based on the transient analysis response whereupon all the standard techniques of static response optimization can be used. In the last decade, the ESL method has been applied to perform the structural optimization of flexible components of mechanical systems modeled as multibody systems (MBS). The ESL evaluation strongly depends on the adopted formulation to describe the MBS and has been initially derived based on a floating frame of reference formulation. In this paper, we propose a method to derive the ESL adapted to a nonlinear finite element approach based on a Lie group formalism for two main reasons. Firstly, the finite element approach is completely general to analyze complex MBS and is suitable to perform more advanced optimization problems like topology optimization. Secondly, the selected Lie group formalism leads to a formulation of the equations of motion in the local frame, that turns out to be a strong practical advantage for the ESL evaluation. Examples are provided to validate the proposed method. [less ▲]

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See detailLe médicament du mois. Insuline glargine 300 U/mL (Toujeo®)
SCHEEN, André ULg

in Revue Médicale de Liège (2016), 71

Summary : This article presents a new formulation of insulin glargine concentrated at 300 U/mL (Gla-300). It is commercialized under the trade name of Toujeo® in an optimized pre-filled SoloStar™ pen for ... [more ▼]

Summary : This article presents a new formulation of insulin glargine concentrated at 300 U/mL (Gla-300). It is commercialized under the trade name of Toujeo® in an optimized pre-filled SoloStar™ pen for the treatment of type 1 and type 2 diabetes in adults. Besides a threefold higher concentration compared to the classical insulin Lantus® (100 U/mL or Gla-100), both pharmacokinetic and pharmacodynamic profiles of Gla-300 are flatter and longer (more than 24 hours) and have a lesser intra-/inter-variability, which makes them more reproducible. Overall, Toujeo® offers the same hypoglycaemic efficacy and the same safety profile when compared with Lantus®. However, a lower risk of hypoglycaemia, especially at night, a slightly smaller weight gain and a better flexibility in the time of injection have been reported. The two insulin formulations are not bioequivalent and the daily insulin requirement is slightly higher with insulin Gla-300 than with insulin Gla-100. The shift from an already available basal insulin towards Toujeo® may require a dose adjustment and a reinforcement of blood glucose monitoring. [less ▲]

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See detailIntroduction
Fallon, Catherine ULg; Aubin, David; Albarello, Luc et al

in Aubin, David; Albarello, Luc; Fallon, Catherine (Eds.) et al Penser l'évaluation des politiques publiques (2016)

Ce livre s’adresse à toutes les personnes qui a des titres divers sont concernés par l’évaluation des politiques publiques parce qu’ils doivent en assurer la réalisation ou en encadrer la démarche. Les ... [more ▼]

Ce livre s’adresse à toutes les personnes qui a des titres divers sont concernés par l’évaluation des politiques publiques parce qu’ils doivent en assurer la réalisation ou en encadrer la démarche. Les exemples et les angles de discussion sont les plus larges possibles pour que le lecteur puisse s’approprier les outils quel que soit son secteur de responsabilité et quel que soit son territoire. Il trouvera dans la suite des chapitres non pas un livre de recettes – ce qui nous semble contraire à la logique d’évaluation de politiques – mais des cadres de réflexion, des propositions de pratiques, ainsi que des références complémentaires pour développer ses pratiques tout en mobilisant un regard critique. [less ▲]

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