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See detailProteomic signatures reveal a dualistic and clinically relevant classification of anal canal carcinoma
Herfs, Michael ULg; Longuespée, Rémi ULg; Quick, Charles et al

in Journal of Pathology (The) (2017), 241

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See detail"On se débrouille". How to be a good judge when the state lets you down
Andreetta, Sophie ULg; Kolloch, Annalena

E-print/Working paper (2017)

Over the last couple of years, Beninese magistrates have gone on multiple strikes. Most of them complain about their substantial workload, low pay, and poor working conditions. They also highlight the ... [more ▼]

Over the last couple of years, Beninese magistrates have gone on multiple strikes. Most of them complain about their substantial workload, low pay, and poor working conditions. They also highlight the discrepancies between the magistrates’ social status and what their families expect from them. While there seems to be a professional malaise within the Beninese bench, judges and prosecutors also insist on the importance of their work and the ethics that goes together with it. This is why we will be looking at the discourses and representations of the social and professional status of Beninese judges. Why do young lawyers choose the path of being a magistrate over other legal careers? How do judges and prosecutors in the Republic of Benin balance professional ethos with practical work routine? [less ▲]

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See detailIn Memoriam Léon Lacroix (1909-2016)
Rochette, Bruno ULg

in Antiquité Classique (2017), 86

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See detailDepth-speci c Fluctuations of gene expression and protein abundance modulate the photophysiology in the seagrass Posidonia oceanica
Procaccini, Gabriele; Ruocco, Miriam; Marin-Guirao, Lazaro et al

in Scientific Reports (2017), 7(42890), 1-14

We present the results of a multiple organizational level analysis conceived to identify acclimative/ adaptive strategies exhibited by the seagrass Posidonia oceanica to the daily uctuations in the light ... [more ▼]

We present the results of a multiple organizational level analysis conceived to identify acclimative/ adaptive strategies exhibited by the seagrass Posidonia oceanica to the daily uctuations in the light environment, at contrasting depths. We assessed changes in photophysiological parameters, leaf respiration, pigments, and protein and mRNA expression levels. The results show that the diel oscillations of P. oceanica photophysiological and respiratory responses were related to transcripts and proteins expression of the genes involved in those processes and that there was a response asynchrony between shallow and deep plants probably caused by the strong di erences in the light environment. The photochemical pathway of energy use was more e ective in shallow plants due to higher light availability, but these plants needed more investment in photoprotection and photorepair, requiring higher translation and protein synthesis than deep plants. The genetic di erentiation between deep and shallow stands suggests the existence of locally adapted genotypes to contrasting light environments. The depth-speci c diel rhythms of photosynthetic and respiratory processes, from molecular to physiological levels, must be considered in the management and conservation of these key coastal ecosystems. [less ▲]

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See detailIntentionalisme et phénoménologie de l'intentionnalité
Seron, Denis ULg

in Etudes Phénoménologiques - Phenomenological Studies (2017), 1

This paper presents an argument in favor of a “phenomenological” approach to intentionality. This approach, as I see it, involves the view that intentional facts are better expressed with the help of ... [more ▼]

This paper presents an argument in favor of a “phenomenological” approach to intentionality. This approach, as I see it, involves the view that intentional facts are better expressed with the help of appearance words (“seems”, “appears”, “is similar to”, etc.). By contrast, what I call the “intentionalist approach” assumes that intentional facts are better expressed by intentional verbs. The argument is as follows. First, it is well-known that the use of intentional verbs to express typically intentional facts generates anomalies with respect to existential generalization, substitution of identicals, and the principle of excluded middle. Secondly, I argue that the use of appearance words does not generate the same anomalies, which suggests that appearance words are more appropriate to describe intentional facts. This, I conclude, is an argument for preferring the phenomenological to the intentionalist approach to intentionality. [less ▲]

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See detailRecovery of fibers and biomethane from banana peduncles biomass through anaerobic digestion
AwedemWobiwo, Florent; Korangi Alleluya, Virginie; Happi Emaga, Thomas et al

in Energy for Sustainable Development (2017), 37

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See detailCounting the number of non-zero coefficients in rows of generalized Pascal triangles
Leroy, Julien ULg; Rigo, Michel ULg; Stipulanti, Manon ULg

in Discrete Mathematics (2017), 340

This paper is about counting the number of distinct (scattered) subwords occurring in a given word. More precisely, we consider the generalization of the Pascal triangle to binomial coefficients of words ... [more ▼]

This paper is about counting the number of distinct (scattered) subwords occurring in a given word. More precisely, we consider the generalization of the Pascal triangle to binomial coefficients of words and the sequence (S(n))n≥0 counting the number of positive entries on each row. By introducing a convenient tree structure, we provide a recurrence relation for (S(n))n≥0. This leads to a connection with the 2-regular Stern–Brocot sequence and the sequence of denominators occurring in the Farey tree. Then we extend our construction to the Zeckendorf numeration system based on the Fibonacci sequence. Again our tree structure permits us to obtain recurrence relations for and the F-regularity of the corresponding sequence. [less ▲]

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See detailFuture-oriented mental time travel in individuals with disordered gambling.
Noel, Xavier; Saeremans, Melanie; Kornreich, Charles et al

in Consciousness & Cognition (2017), 49

This study investigated the ability of individuals with disordered gambling to imagine future events. Problem gamblers (n=35) and control participants (n=35) were asked to imagine positive and negative ... [more ▼]

This study investigated the ability of individuals with disordered gambling to imagine future events. Problem gamblers (n=35) and control participants (n=35) were asked to imagine positive and negative future events for three temporal distances (one week, one year, 5-10years). Then, a variety of phenomenological aspects of their future thoughts (e.g., sensory and contextual details, autonoetic consciousness) were rated. Compared to control subjects, problem gamblers generated fewer positive and negative events across all temporal distances, an impairment that was correlated to verbal fluency scores. Furthermore, problem gamblers rated imagined events as containing fewer sensory and contextual details, and lacking autonoetic consciousness. These findings demonstrate that problem gambling is associated with a reduced future-oriented mental time travel ability and, in particular, with diminished autonoetic consciousness when imagining future events. [less ▲]

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See detailThe role of mesenchymal stem cells in the treatment of ulcerative colitis and Crohn's disease
GREGOIRE, Céline ULg; Louis, Edouard ULg; BRIQUET, Alexandra ULg et al

in Atkinson, K; Ed (Eds.) The Biology and Therapeutic Applications of Mesenchymal Cells (2017)

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See detailFormaliser le trope : De la subjectivité linguistique à la subjectivité épilinguistique
Mathy, Adrien ULg

in Signata. Annales des Sémiotiques = Annals of Semiotics (2017)

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See detailUsefulness of multi-breed models in genetic evaluation of direct and maternal calving ease in Holstein and Belgian Blue Walloon purebreds and crossbreds
Vanderick, Sylvie ULg; Gillon, Alain; Glorieux, Géry et al

in Livestock Science (2017)

The objective of this study was to verify the feasibility of a joint genetic evaluation system for calving ease trait of Belgian Blue (BBB) and Holstein (HOL) Walloon cattle based on data of purebred and ... [more ▼]

The objective of this study was to verify the feasibility of a joint genetic evaluation system for calving ease trait of Belgian Blue (BBB) and Holstein (HOL) Walloon cattle based on data of purebred and crossbred animals. Variance components and derived genetic parameters for purebred BBB and HOL animals were estimated by using single-breed linear animal models. This analysis showed clear genetic differences between breeds. Estimates of direct and maternal heritabilities (± standard error) were 0.34 (±0.02) and 0.09 (±0.01) for BBB, respectively, but only 0.09 (±0.01) and 0.04 (±0.01) for HOL, respectively. Moreover, a significant negative genetic correlation between direct and maternal effects was obtained in both breeds: −0.46 (±0.04) for BBB and −0.29 (±0.11) for HOL. Variance components and derived genetic parameters for purebred BBB and HOL and crossbred BBB ×× HOL cattle were then estimated by using two multi-breed linear animal models: a multi-breed model based on a random regression test-day model (Model MBV), and a multi-breed model based on the random regression multi-breed model (Model MBSM). Both multi-breed models use different functions of breed proportions as random regressions, thereby enabling modelling different additive effects according to animal's breed composition. The main difference between these models is the way in which relationships between breeds are accounted for in the genetic (co)variance structure. Genetic parameters differed between single-breed and multi-breed analysis, but are similar to the literature. For BBB, estimates of direct and maternal heritabilities (±SE) were 0.45 (±0.07) and 0.08 (±0.01) by using Model MBV, and 0.45 (±0.08) and 0.09 (±0.02) for Model MBSM, respectively. For HOL, these estimates were 0.18 (±0.04) and 0.05 (±0.01) using Model MBV, and 0.16 (±0.04) and 0.05 (±0.01) for Model MBSM, respectively. Reliability gains (up to 25%) indicated that the use of crossbred data in the multi-breed models had a positive influence on the estimation of genetic merit of purebred animals. A slight re-ranking of purebred sires and maternal grandsires was observed between single-breed and multi-breed models. Moreover, both multi-breed models can be considered as quasi-equivalent models because they performed almost equally well with respect to MSE and correlations, for purebred and crossbred animals. [less ▲]

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See detailMesenchymal stromal cell therapy for inflmmatory bowel diseases
GREGOIRE, Céline ULg; GREGOIRE, Céline ULg; LECHANTEUR, Chantal ULg et al

in Alimentary Pharmacology & Therapeutics (2017), 45

Background Inflammatory bowel diseases (IBD) are chronic relapsing diseases in which pro-inflammatory immune cells and cytokines induce intestinal tissue damage and disability. Mesenchymal stromal cells ... [more ▼]

Background Inflammatory bowel diseases (IBD) are chronic relapsing diseases in which pro-inflammatory immune cells and cytokines induce intestinal tissue damage and disability. Mesenchymal stromal cells (MSCs) exert powerful immunomodulatory effects and stimulate tissue repair. Aim To review the current data on mesenchymal stromal cell therapy in IBD. Method We searched PubMed and ‘ClinicalTrials.gov’ databases using the terms ‘mesenchymal stromal cells’, ‘mesenchymal stem cell transplantation’, ‘inflammatory bowel diseases’, ‘Crohn disease’ and ‘colitis, ulcerative’. Additional publications were identified from individual article reference lists. Results MSCs include inhibition of Th1/Th17 lymphocytes and recruitment of regulatory T lymphocytes, induction of antigen-presenting cells into a regulatorylike profile, and stimulation of epithelial cell differentiation and proliferation. More than 200 patients with refractory fistulas have been treated with local injections of MSCs, resulting in complete response in more than half, and in overall response in approximately two thirds of patients. In refractory luminal Crohn’s disease, 49 cases of systemic MSC infusions have been reported, while trials with autologous MSCs resulted in mitigated responses, studies using allogeneic MSCs were promising, with around 60% of patients experiencing a response and around 40% achieving clinical remission. Conclusions Mesenchymal stromal cells might represent a promising therapy for IBD, especially for Crohn’s disease. There remain many unsolved questions concerning the optimal origin and source of mesenchymal stromal cells, dosage and modalities of administration. Moreover, mesenchymal stromal cells still need to prove their effectiveness compared with conventional treatments in randomised controlled trials. [less ▲]

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See detailRoad and intermodal transport performance: the impact of operational costs and air pollution external costs
Mostert, Martine ULg; Caris, An; Limbourg, Sabine ULg

in Research in Transportation Business & Management (2017)

The transportation of goods is essential for the economy, but it also contributes to air pollution which, in turn, affects human health. These negative impacts generate additional costs for society that ... [more ▼]

The transportation of goods is essential for the economy, but it also contributes to air pollution which, in turn, affects human health. These negative impacts generate additional costs for society that are not necessarily taken into account in public transportation policies and in private transportation decisions of companies and individuals. This leads to inefficient transportation systems where the social equilibrium is not reached. Intermodal transport is promoted by the European Commission to reduce these negative externalities. The objective of this paper is to analyze at a strategic level the effect on modal split between road, intermodal rail and intermodal inland waterway transport of several economic or environmental policies. An intermodal allocation model is applied to the Belgian case in order to identify the modal split changes between the single minimization of costs (operational or health-related external) and the introduction of additional road taxes. [less ▲]

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See detailDon't judge a fish by its fins: species delineation of Congolese Labeo (Cyprinidae)
Van Steenberge, Maarten; Gajdzik, Laura ULg; Chilala, Alex et al

in Zoologica Scripta (2016)

Conspicuous characters are often useful in species identification. Yet, identification and delineation are two different processes, and such characters do not necessarily provide the best basis on which ... [more ▼]

Conspicuous characters are often useful in species identification. Yet, identification and delineation are two different processes, and such characters do not necessarily provide the best basis on which species can be delineated. This is illustrated by the case of the Labeo with papillary lips from the Congo basin. Traditionally, species delineation in this group was based on a conspicuous trait: the shape of the dorsal fin, which shows a profound degree of differentiation. Morphometric analyses were performed on 185 specimens both with and without measurements taken on this fin. The groups obtained using these two approaches were compared with those obtained through DNA barcoding. For this, 24 sequences of the standard barcoding COI gene were obtained. Species delineations based on morphological and molecular results were in agreement when the shape of the dorsal fin was ignored. This suggested that of the five nominal species known from the Congo basin, L. altivelis, L. rosae, L. lineatus, L. weeksii and L. maleboensis, only the former three remain valid. Consequently, L. weeksii was synonymised with L. altivelis and L. maleboensis with L. lineatus. The sole Congo basin endemic is L. lineatus as L. altivelis and L. rosae also occur in more southern basins. The use of the shape of the dorsal fin in morphological studies has previously led to overestimates of species diversity in this group. This is due to the fact that L. altivelis shows a remarkable amount of geographical variation for this trait. The large amount of intra- and interspecific variation in this character was caused by differential allometric growth in different parts of the dorsal fin. [less ▲]

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See detailComprehension of an organosolv process for lignin extraction on Festuca arundinacea and monitoring of the cellulose degradation
Schmetz, Quentin ULg; Maniet, Guillaume ULg; Jacquet, Nicolas ULg et al

in Industrial Crops and Products (2016), 94

It is commonly accepted that the current society needs to partially substitute fossil resources by renewable ones. Among many solutions, one approach consists in the development of biorefinery involving ... [more ▼]

It is commonly accepted that the current society needs to partially substitute fossil resources by renewable ones. Among many solutions, one approach consists in the development of biorefinery involving lignocellulosic biomass to produce bio-based materials and fuels. This study focuses on the comprehension of an organosolv treatment designed to break the complex lignocellulosic structure for high purity lignin extraction from tall fescue (Festuca arundinacea Schreb.). This grass benefits from an increasing interest in Western Europe and has been suggested as feedstock for biorefinery. However, its use as material for high purity lignin production has not been determined yet. Ethanol/water, 92/8% [v/v] with H2SO4 0.32 M was investigated at pilot scale under conventional heating (5 °C min−1 during 30 min and stabilized at 148 °C for 5 min). Precipitated lignin were analyzed as well as the composition of side-stream products (recovered cellulosic pulp and the aqueous hydrolysate). Lignin has been recovered at a purity level of 90% with a yield of 60%. The main contaminants were nitrogen containing compounds and degraded hemicelluloses. 2D-HSQC NMR (Two Dimension-Heteronuclear Single Quantum Correlation Nuclear Magnetic Resonance) revealed a co-extraction of ferulates and coumarates function as well as arabinoxylan. Cellulose was recovered at 53% purity with 60% yield. The conditions appear to be too harsh for tall fescue and led to significant amount of cellulose degradation. A process using a lower alcohol concentration will be developed to provide better yields of both cellulose and lignin. [less ▲]

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See detailContinuous Production of Itraconazole-based Solid Dispersions by Hot Melt Extrusion: Preformulation, Optimization and Design Space Determination.
Thiry, Justine ULg; Lebrun, Pierre; Vinassa, Chloé et al

in International Journal of Pharmaceutics (2016), 515(1-2), 114-124

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See detailInterpellation du genre et sujets mélancoliques. Butler lectrice d’Althusser
Borotto, Jessica ULg

in Cahiers du GRM (2016), 8

Cet article propose d’explorer la manière dont Judith Butler remobilise la thèse althussérienne de l’interpellation dans La Vie psychique du pouvoir . Nous essaierons de saisir les éléments qui nous ... [more ▼]

Cet article propose d’explorer la manière dont Judith Butler remobilise la thèse althussérienne de l’interpellation dans La Vie psychique du pouvoir . Nous essaierons de saisir les éléments qui nous paraissent enrichir la problématique althussérienne, suggérant que la compréhension de la dimension psychique du pouvoir qui ressort de sa lecture permet de complexifier la relation du sujet au pouvoir. Afin de tisser des liens précis entre l’interpellation chez Althusser et la subjectivation chez Butler, nous examinerons d’abord le rôle que Nietzsche et Foucault recouvrent dans la formulation de la théorie de la subjectivation chez Butler. Ensuite, il s’agit de comprendre en quoi la matérialité et l’ambiguïté des mécanismes de subjectivation, qui déjà caractérisent l’interpellation althussérienne, deviennent chez Butler les sources d’une relation critique aux conditions d’émergence du sujet. Enfin nous préciserons comment elle mobilise de telles sources pour élaborer cette figure de la psychanalyse qu’est la mélancolie et pour décrire sa transformation en deuil. [less ▲]

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See detailIs Competence a Holy Grail for Teaching? Reflections on Nursing Education
Dancot, Jacinthe ULg

in Nursing & Care Open Access Journal (2016), 1(4), 00021

The competence-based approach is largely widespread in the nursing schools and is viewed as a golden standard for professional teaching. But the practical use of the concept is varying among institutions ... [more ▼]

The competence-based approach is largely widespread in the nursing schools and is viewed as a golden standard for professional teaching. But the practical use of the concept is varying among institutions and even teachers. The goal of this narrative review is to clarify the conception of competence and its use in the fields of education and nursing. Regarding education, Gonczi, Tardif, Jonnaert and Beckers are the key authors referred to. A first apparent consensus over the holistic nature of the competence quickly gives place to the observation of important nuances in conceptions. Similarly, in the field of nursing, Benner is first discussed, and recent literature reviews and concept analyses are taken into account: similar nuances are detected, as well as difficulties in the practical implementation of the concept. Considering the lack of consensus and the paradigmaticalincoherences detected among the sources consulted for this review, we question the use of competence as single point of view for teaching and assessing, and we propose other avenues to be explored in order to recognize emergent professionality. [less ▲]

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See detailLearning from Incidents and Incident Reporting: Safety Governance at a Belgian Nuclear Research Center
Rossignol, Nicolas ULg; Van Oudheusden, Michiel ULg

in Science, Technology & Human Values (2016), Online First

This article examines how incidents are governed in a Belgian Nuclear Research Center by way of an incident reporting system named REX. Drawing on a documentary analysis of incident reports, interviews ... [more ▼]

This article examines how incidents are governed in a Belgian Nuclear Research Center by way of an incident reporting system named REX. Drawing on a documentary analysis of incident reports, interviews and focus groups with personnel, it illustrates how REX enacts a safety governmentality centered on identifying incident causes and culprits. As this governmentality mode obscures the epistemic and political character of incidents, it closes down important opportunities for collective learning about safety and safety governance. It is argued that joint reflection about incidents and resistances towards incident reporting serve as fruitful starting points for a more reflexive safety governance that makes explicit how decisions are made in high-risk contexts. Social scientists can enhance governance of this kind by pointing to different perceptions and evaluations of incidents and by insisting that contending interpretations are confronted and accounted for. [less ▲]

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