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See detailStudy of the evolution of the osteoarthritis pathology and the mechanical properties of cartilage in a spontaneous osteoarthritis model in the Dunkin-Hartley guinea pigs.
Legrand, Catherine ULg; Centonze, Prescilia ULg; Comblain, Fanny ULg et al

Poster (2017, April 27)

In animal models, the severity of cartilage damage is assessed by histological scores evaluating the structure, the proteoglycan content, the integrity of the tidemark, the cellularity, and osteophytes ... [more ▼]

In animal models, the severity of cartilage damage is assessed by histological scores evaluating the structure, the proteoglycan content, the integrity of the tidemark, the cellularity, and osteophytes. In parallel to these histological analyzes, we studied the mechanical properties of cartilage at different stages of disease progression in the Dunkin-Hartley guinea pigs. We also correlated the severity of histological lesions with the mechanical properties of cartilage. [less ▲]

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See detailGénéralisation et raisonnement analogique chez les enfants porteurs de dysphasie
Krzemien, Magali ULg

Scientific conference (2017, April 27)

Cette présentation s’intéressera aux capacités de généralisation des enfants porteurs de dysphasie. Nous aborderons tout d’abord les études démontrant que ces enfants présentent des difficultés de ... [more ▼]

Cette présentation s’intéressera aux capacités de généralisation des enfants porteurs de dysphasie. Nous aborderons tout d’abord les études démontrant que ces enfants présentent des difficultés de productivité et de créativité syntaxique et sont davantage dépendants de l’input auquel ils sont confrontés. Ces difficultés semblent également être présentes au niveau de l’acquisition lexicale. Nous verrons ensuite que la capacité à créer des analogies semble être un processus essentiel à la généralisation. Or, plusieurs études mettent en évidence un déficit de raisonnement analogique dans la dysphasie, en particulier dans des situations plus complexes et abstraites. Un possible lien entre le raisonnement analogique, la généralisation et le langage dans la dysphasie sera donc envisagé. Nous terminerons en envisageant l’influence de la variabilité sur la généralisation et l’extension de ces hypothèses aux enfants porteurs de troubles du spectre autistique. [less ▲]

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See detailLa force des mots. Mémoire et Shoah au XXIe siècle
Grandjean, Geoffrey ULg

Conference given outside the academic context (2017)

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See detailMeeting Fronstage, Deciding Backstage
Slomian, Cynthia ULg

Conference (2017, April 27)

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See detail“New Ways of Working” and their managerial myths: the resurgence of liberation and distributed surveillance?
Jemine, Grégory ULg

Conference (2017, April 27)

Through this contribution we aim to explore how two well-known bodies of knowledge, namely the panopticism as developed by Foucault (2012) and the works from the Human Relations movement (Mayo, 1949) are ... [more ▼]

Through this contribution we aim to explore how two well-known bodies of knowledge, namely the panopticism as developed by Foucault (2012) and the works from the Human Relations movement (Mayo, 1949) are being reprocessed and reinjected by managerial actors in organisational projects of “modernisation” such as “New Ways of Working”. Nowadays, in open and flexible workspaces, visual and acoustic privacy at work tend to disappear (Van der Voort, 2004) which leaves room for a constant monitoring of employees’ behaviours, mainly performed by the peers (Sewell & Taskin, 2015). The old managerial myth of distributed surveillance resurfaces as everyone is in a position to monitor his colleagues, generating a global feeling of unease. Simultaneously several managerial discourses advocate for abolishing direct supervision and liberating the employees of the bureaucratic factors through self-managed teams and empowerment. The defenders of “freedom” in companies build their argumentation on former findings from the Human Relations movement such as the improved efficiency of small groups and the benefits of removing rules. In an historical perspective, we wonder why and how such elements of knowledge produced several decades ago now become performative in several Belgian companies. [less ▲]

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See detailX-LAG: How did they grow so tall?
BECKERS, Albert ULg; Rostomyan, Liliya ULg; Potorac, Iulia ULg et al

in Annales d'Endocrinologie (2017)

X-linked acrogigantism (XLAG) is a new, pediatric-onset genetic syndrome, due to Xq26.3 microduplications encompassing the GPR101 gene. XLAG has a remarkably distinct phenotype with disease onset ... [more ▼]

X-linked acrogigantism (XLAG) is a new, pediatric-onset genetic syndrome, due to Xq26.3 microduplications encompassing the GPR101 gene. XLAG has a remarkably distinct phenotype with disease onset occurring before the age of 5 in all cases described to date, which is significantly younger than in other forms of pituitary gigantism. These patients have mixed GH and prolactin positive adenomas and/or mixed-cell hyperplasia and highly elevated levels of GH/IGF-1 and prolactin. Given their particularly young age of onset, the significant GH hypersecretion can lead to a phenotype of severe gigantism with very advanced age-specific height Z-scores. If not adequately treated in childhood, this condition results in extreme final adult height. XLAG has a clinical course that is highly similar to some of the tallest people with gigantism in history. « X-linked acrogigantism » (XLAG) est un syndrome pédiatrique récemment décrit, lié à des microduplications du chromosome Xq26.3, englobant le gène GPR101, responsable de l’affection. Les patients XLAG présentent un phénotype remarquablement distinct des autres cas de gigantisme hypophysaire. Dans tous les cas décrits, la maladie s’exprime avant 5 ans soit beaucoup plus tôt que dans les autres formes. Les patients ont habituellement un gros adénome ou une hyperplasie mixte pour la GH et la prolactine et des taux très élevés de GH/IGF1 et prolactine. En raison de son début très précoce, l’hypersécrétion importante de GH peut conduire à un gigantisme extrêmement sévère avec un Z-score très important pour l’âge. Si cette condition n’est pas traitée pendant l’enfance, elle peut conduire à une taille finale extrême. XLAG montre une évolution clinique similaire à celle observée chez les géants les plus grands de l’histoire. [less ▲]

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See detailClimate change and insect pests: Impact on carbon dioxide increase on aphid behavior and semiochemistry
Boullis, Antoine ULg

Doctoral thesis (2017)

There is no longer any doubt on the incidence of rising carbon dioxide (CO2) concentration on global change. Climate modifications are responsible of perturbations in interactions between living organisms ... [more ▼]

There is no longer any doubt on the incidence of rising carbon dioxide (CO2) concentration on global change. Climate modifications are responsible of perturbations in interactions between living organisms. This research topic is in the light of scientists since several decades and is considered to be of major interest in the understanding of future ecosystems’ functioning. In this prospect, interactions between insect herbivores and their natural enemies have received little attention under a climate change scope, while they are of paramount importance in the proper equilibrium of agro-ecosystems. As the efficacy of natural enemies is governed largely by behavioral mechanisms, changes in the predators’ behaviors but also in those related to prey defenses can change the dynamics of insect populations. As aphids are considered as one of the main crop pests in temperate regions, relative literature on impact of increases in atmospheric CO2 concentrations on aphid population dynamic now exists. However, few publications about their chemical ecology are reported. Aphids are using many chemical signals to communicate with each other or in their interactions with higher trophic levels. Here, I tempted to identify the impact of an increase in atmospheric CO2 concentration on the interactions between aphids and their natural enemies mediated by semiochemicals. Aspects of phytovirus transmission by aphids were also covered. After being involved in three literature reviews, I was interested in the aphid alarm signaling which strongly supports aphid-predators interactions. In the pea aphid Acyrthosiphon pisum (Harris), this signaling is mediated by a pheromone, namely the (E)-β-farnesene. For my experiments, I took into consideration the importance of all the steps that this molecule has to pass by, from its production into the emitter individual to the induced behavioral response of the receivers. The results obtained during these experiments highlighted an imbalance in aphid chemical communication for populations grown under elevated CO2 conditions, by modifications in several steps of the signal (decrease in pheromone production, emission and associated behavior). The results obtained here were supported by previous studies indicating that increases in CO2 concentration reduce the aphid escape behavior, which makes them potentially more susceptible to predation. We know that many plant pathogens are dependent on aphid dispersal to spread, so it is of major importance to predict how these insect vectors could be affected by forecasted climate. I thus carried my interest on the ability of aphids to transmit phytoviruses under changing atmosphere. Using another aphid model, the green peach aphid Myzus persicae (Sulzer), we have not observed any modifications in terms of virus and aphid spread in laboratory trials when tested under either actual or forecasted CO2 concentration. However, the viral transmission efficiency via aphids is increased under CO2-enriched atmosphere. Finally, the host searching behavior of an aphid predator was studied. The efficiency of natural enemies of insect pests is mainly driven by their ability to find food sources or oviposition sites in their environment. The conducted study highlighted the preference of the hoverfly Episyrphus balteatus De Geer towards aphid colonies grown under actual CO2 levels, suggesting modifications in chemical cues guiding hoverflies to a suitable oviposition site, due to increase of CO2. The results and knowledge obtained during these studies will add novel information on how a major component of climate change may impact tritrophic interactions and thus the efficiency of natural enemies of insect herbivores in biological control scope. [less ▲]

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See detailPISA expliqué à tous : pistes pour améliorer l'enseignement en FW-B
Lafontaine, Dominique ULg

Scientific conference (2017, April 27)

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See detailImportin-8 could cause CAE/JME by delaying early neuroblast migration
Nganou, Gerry ULg; Tanaka, Miyabi; Coumans, Bernard ULg et al

Poster (2017, April 27)

Abstract : Childhood Absence Evolving to Juvenile Myoclonic Epilepsy (CAE/JME) is an uncommon form of genetic generalized epilepsy that appears as absence in childhood and evolves into generalized ... [more ▼]

Abstract : Childhood Absence Evolving to Juvenile Myoclonic Epilepsy (CAE/JME) is an uncommon form of genetic generalized epilepsy that appears as absence in childhood and evolves into generalized tonic–clonic seizures with myoclonic jerks during adolescence. In some family of patients affected by CAE/JME, mutations have been observed in the gene encoding for the transport protein importin-8 (IPO8). IPO8 could be at the origin of CAE/JME via its role in the transport of its targets (like Ago-2, Smad4, c-Jun). RT-qPCR has shown that IPO8 mRNA is expressed at all ages with no big difference in expression level. Using ISH, a clear expression of mIPO8 mRNA was observed in the sub-ventricular/ventricular zone (SVZ/VZ), the cortical plate (CP) and the ganglionic eminences (GE) of developing brain at E14. Both SVZ/VZ and GE are the “neurogenic niches” that generate glutamatergic and GABAergic neurons respectively. The implication of IPO8 in the generation of “glutamatergic neurons” was investigated by In Utero electroporation (IUE) and MGE Electroporation. Using shRNA, we observed that after 3 days, “glutamatergic neuroblasts” do not reach the CP in contrast to the control condition. This effect can be rescued by the co-expression of a form of IPO8 that is resistant to the shRNA. When overexpressing the pathological forms of hIPO8, but not a variant, migration of “glutamatergic neuroblasts” was also impaired. However, when the observation is made later, i.e. at P5, we observed that the neuroblasts finally reach their correct layer in the cortex, suggesting IPO8 only delayed but not blocked migration. Moreover, shRNA against IPO8 mRNA lead to alteration of interneurons (GABAergic neurons) migration same to overexpression of one mutated form of IPO8. Conclusion : IPO8 is expressed in mouse brain during development. It shows a clear expression during embryogenesis in the “neurogenic niches”. Moreover, IPO8 modulates neuroblasts (radial and tangential) migration in the developing brain. So, abnormal brain development due to IPO8 mutations could be at the origin of CAE/JME. [less ▲]

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See detailPraxis, besoins et impératifs affectifs : Réflexions sur la normativité de la conscience émue.
Recchia, Fabio ULg

Conference (2017, April 26)

L'objectif de cette communication consiste à dégager les caractéristiques normatives de la conscience émue. Nous mobiliserons pour ce faire la thématique des "impératifs affectifs", qui est abondamment ... [more ▼]

L'objectif de cette communication consiste à dégager les caractéristiques normatives de la conscience émue. Nous mobiliserons pour ce faire la thématique des "impératifs affectifs", qui est abondamment discutée par Sartre dans "Les Racines de l'éthique". Sur cette base, nous développerons une réflexion en trois temps. 1° Nous situerons tout d'abord les "Racines de l'éthique" dans la continuité des réflexions de "l'Esquisse d'une théorie des émotions". 2° Nous montrerons ensuite que l'analyse des impératifs affectifs enveloppe une critique du positivisme, qui est une approche massivement adoptée par nombre de philosophie des émotions. 3° Enfin, nous approfondirons la description sartrienne des impératifs affectifs à partir de "L'Émile" de Jean-Jacques Rousseau. L'association de l'un et l'autre texte nous permettra en effet de commenter la "seconde forme d'émotion" qui est très allusivement décrite par les dernières pages de l'Esquisse d'une théorie des émotions. Plus largement, ce détour par la philosophie politique des modernes permettra d'établir un dialogue entre la phénoménologie sartrienne de l'affectivité et l'approche de la normativité qui est proposée par la philosophie française des sciences sociales. [less ▲]

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See detailThe Matrix of Academic Organising. Articulating organisations’ 3Ds and academics’ logics of action
Dubois, Christophe ULg; Dubois-Shaik, Farah

Scientific conference (2017, April 26)

The aim of this paper is twofold. It firstly aims to account for the Matrix of Excellence, Funding and Omnipresence characterizing academic organizations (Dubois-Shaik & Fusulier, 2016), and more ... [more ▼]

The aim of this paper is twofold. It firstly aims to account for the Matrix of Excellence, Funding and Omnipresence characterizing academic organizations (Dubois-Shaik & Fusulier, 2016), and more precisely their constitutive three dimensions: managerial discourse, formal and parallel structures (Friedberg, 2012; Dubois, 2014). Secondly, drawing on the metaphor of shadow organizing (Gherardi et al., 2017), we will illustrate some informal coping mechanisms occurring in the parallel structure of academic organizations. We will then discuss how these coping mechanisms are or are not being translated in managerial discourse and inscribed in formal structures. [less ▲]

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See detailBaromètre financier du secteur Transport et Logistique : évolution et perspectives
Lambert, Marie ULg

Conference given outside the academic context (2017)

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See detail4th Doctoral Seminar on Sustainability Research in the Built Environment Book of Abstracts
Attia, Shady ULg; Teller, Jacques ULg; Mahy, Grégory ULg

Book published by SBD Lab (2017)

The DS2BE is a joint initiative of research groups working on sustainability issues at 8 Belgian universities: ULBruxelles, VUBrussel, KULeuven, UCLouvain, ULiège, UHasselt, UAntwerpen and UGent ... [more ▼]

The DS2BE is a joint initiative of research groups working on sustainability issues at 8 Belgian universities: ULBruxelles, VUBrussel, KULeuven, UCLouvain, ULiège, UHasselt, UAntwerpen and UGent. Conceived as a platform for PhD researchers whose work engages the built environment at different scales in the framework of sustainability, these seminars provide an excellent opportunity for the doctoral students of the partner institutions to present their ongoing research. They will get feedback from a broad panel of sustainability experts, including invited specialists and peers, for furthering their research. PhD candidates can provide submissions that concern topics, such as: - Sustainable Architecture and Resources, materials, re-cycling /re-use, building elements and envelope, building physics, building construction technology, building renovation, drawing lessons from vernacular, bioclimatic design, regenerative design, biomimetic and integrated design, …, - Sustainability theory, sustainability / environmental assessment at building and neighborhood scales, and at the scale of city and regions, - Sustainable urbanism, urban form, landscape and urban ecology, urban green infrastructure and ecosystem services, public space, density, urban infrastructure & transportation, water urbanism, retrofitting of buildings to the built environment, - Methodologically oriented PhDs focusing on issues related to LCA (Life Cycle Analysis), I-O (Input-Output Analysis), MFA (Material Flow Analysis), simulation techniques, to exploring urban metabolism, industrial ecology, environmental modelling, GIS-based land-use change modelling, to Research by Design. [less ▲]

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See detailConstitutus = καϑεστώς : un hellénisme de la langue juridique ?
Rochette, Bruno ULg

Conference (2017, April 26)

Le participe parfait constitutus (ainsi que positus) a été vu comme une sorte de substitut destiné à pallier l’absence en latin de participe présent du verbe être (*ens, entis). Plusieurs auteurs ont ... [more ▼]

Le participe parfait constitutus (ainsi que positus) a été vu comme une sorte de substitut destiné à pallier l’absence en latin de participe présent du verbe être (*ens, entis). Plusieurs auteurs ont considéré cet emploi comme un hellénisme propre à la langue juridique en soulignant que, dans les Novellae de Justinien, constitutus est une traduction du grec καϑεστώς, qui a un sens actif. On en a déduit qu’il pourrait s’agir d’une particularité de la langue des juristes qui apparaît pour la première fois chez Julianus [4], Scaevola [6], Papinien [5] et Ulpien [8]. Cet emploi, qui ne semble pas antérieur à Sénèque [7], n’est toutefois pas spécifique aux juristes. On le rencontre dans le latin de l’Empire, spécialement chez des auteurs africains chrétiens et païens, comme Apulée [2] et Cyprien de Carthage [3], et surtout dans la langue tardive (Ammien Marcellin [1]). Cet usage pose la question de la spécificité de la langue des juristes et de l’influence éventuelle du grec sur cette langue technique. Une étude plus systématique des prétendus hellénismes chez le juriste Gaius, peut-être d’origine orientale, montre que l’influence du grec sur son latin, si elle a existé, est assez réduite. Un grand nombre de particularités qui ont été considérées comme des hellénismes sont en réalité des spécificités du latin tardif et connaissent des parallèles chez des auteurs comme Apulée, Tertullien, Augustin, Ammien Marcellin. J’étudie ici les emplois de constitutus comme prétendu substitut du participe présent de esse dans un corpus assez large de textes : Arnobe, Firmicus Maternus, Lactance, Hilaire, Lucifer, Ambroise, Jérôme, Sulpice Sévère, Cassien, Orose… jusqu’à Cassiodore. On trouve aussi cette tournure assez souvent dans la Vulgate. Pour expliquer cette spécificité, l’influence du grec n’est pas une donnée nécessaire. Il s’agit essentiellement, comme d’autres phénomènes, d’une évolution du latin, qui a sans doute éprouvé le besoin de combler la lacune de l’absence du participe présent du verbe « être », ce qui arrivera au Moyen Âge avec la création de *ens, entis, déjà proposé par Jules César. Exemples [1] Ammien Marcellin, XX, 3, 12 : eodem adhuc constituto [2] Apulée, Mét., IV, 11 : Tunc nos in ancipiti periculo constituti uel op primendi nostri uel deserendi socii remedium e re nata ualidum eo uolente comminiscimus. [3] Cyprien, Ep., 1, 1 : in clerico ministerio constituti [4] Julianus Dig. 24, 2, 6 : in captiuitate constitutus [5] Papinien Dig. 35, 1, 77, 3 : impubere filia constituta [6] Scaevola Dig. 4, 4, 39, 1 : curatoribus eius idoneis constitutis [7] Sénèque, NQ, III, 10, 3 : natura partes suas velut in ponderribus constitutas exanimat [8] Ulpien Dig. 3, 5, 19 : Ulpianus libro decimo ad edictum. sin autem apud hostes constitutus decessit, et successori et aduersus successorem eius negotiorum gestorum directa et contraria competit. Bibliographie GARCEA A., Caesar’s De analogia. Edition, Translation, and Commentary, Oxford, 2012. KALB W., Das Juristenlatein. Versuch einer Charakteristik auf Grundlage der Digesten, Nürnberg 1888 [Aalen 1961] --, Roms Juristen nach ihrer Sprache dargestellt, Leipzig 1890 [Aalen 1975]. LÖFSTEDT E., Zur Frage der Gräzismen, dans Syntactica. Studien und Beiträge zur historischen Syntax des Lateins II, Lund 1933, 406-457 NELSON H.L.W., Überlieferung, Aufbau und Stil von Gai Institutiones (Studia Gaiana, 6), Leiden 1981, ROSÉN H.-D. SHLEV, QUASI: Its Grecizing [?] syntactic patterns, Colloque de Linguistique latine de Toulouse (sous presse). SCHRIJNEN J.-CHR. MOHRMANN, Studien zur Sprache der Briefe des hl. Cyprian, 2 vol., Nijmegen 1934 [less ▲]

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See detailInterviews on Residential Building Stock Deep Renovation in Belgium
Ruellan, Guirec ULg

Poster (2017, April 26)

Belgium should increase the deep renovation rate of existing residential building stock at least to 3% a year to achieve the EU objectives of decreasing by 80% the Green House Gas Emissions before 2050 ... [more ▼]

Belgium should increase the deep renovation rate of existing residential building stock at least to 3% a year to achieve the EU objectives of decreasing by 80% the Green House Gas Emissions before 2050. Since the first thermal legislations (between 1985 and 2000, depending on the Region), efficiency and comfort of newly built houses have met higher standards. But the renovation rate of residential buildings remained stable in the last 20 years. Only 25000 renovation permits are issued each year, in which a small amount of them are highly energy efficient. Literature review has showed that drivers and barriers of deep renovation are many and varied, sometimes contradictory and often underestimated. Conducted interviews with experts who study different facet of renovation present some others viewpoints on this subject. According to their own specific experience, each interviewee thinks differently on possible solutions. The poster set out the interview analysis. Some points are very close to the literature review, such as the environmental and economic issues of the residential renovation, while other results are solely extracted based on the interviews’ results. Amongst others, the necessity to maintain and improve the existing building stock to new standards takes an important place. The regulation appears to be a good driver as much as a barrier, depending on the local legislations and buildings context particularly in Belgium where the diversity of the building stock is very important. Public policies seem to be the first tools to unlock the renovation rate even if the development of new financial model and the information of stakeholders are also highlighted. This analysis increases the comprehension of the renovation topic on a new level, including some adjacent ideas that lead to better understanding of the existing barriers and possible strategies to overtake them, so that to involve everyone in the renovation strategy definition to promote the most efficient one. [less ▲]

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