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See detailLike human adipose tissue and dermis, human bone marrow harbor cells with neural crest-associated characteristics.
Wislet, Sabine ULg

Conference (2016, November 12)

Adult neural crest stem cells (NCSC) are of extraordinary high plasticity and promising candidates for a use in regenerative medicine. Several locations like skin, adipose tissue, dental pulp or bone ... [more ▼]

Adult neural crest stem cells (NCSC) are of extraordinary high plasticity and promising candidates for a use in regenerative medicine. Several locations like skin, adipose tissue, dental pulp or bone marrow have been described in rodent. However, very few information is available concerning their correspondence in human tissues. The main objective of this study was therefore to characterize NCSC from adult human bone marrow. In this purpose, we compared human bone marrow stromal cells to human adipose tissue and dermis, already described for containing NCSC. We performed comparative analyses in terms of gene and protein expression, as well as functional characterizations. It appeared that human bone marrow, similarly to adipose tissue and dermis contains NESTIN+ / SOX9+ / TWIST+ / SLUG+ / P75NTR+ / BRN3A+/ MSI1+/ SNAIL1+ cells and were able to differentiate into melanocytes and Schwann cells. Moreover, when injected into chicken embryos, all those cells were able to migrate and follow endogenous neural crest migration pathways. Altogether, the phenotypic characterization and migration abilities strongly suggest the presence of neural crest-derived cells in human adult bone marrow. [less ▲]

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See detailImages et figures. Dispositifs de re-découpage du sensible (Rancière)
Hagelstein, Maud ULg

Conference (2016, November 12)

Dans son historiographie critique (Les noms de l’histoire, 1992 / Figures de l’histoire, 2012), J. Rancière définit pour l’époque contemporaine des formes alternatives de poétique, de mise en récit et de ... [more ▼]

Dans son historiographie critique (Les noms de l’histoire, 1992 / Figures de l’histoire, 2012), J. Rancière définit pour l’époque contemporaine des formes alternatives de poétique, de mise en récit et de mise en visibilité de l’histoire, qui auraient pour effet de mieux prendre en compte les anonymes et de découper autrement le sensible. Dans de nombreux textes (cf. par ex. Le destin des images, sur la « phrase-image »), Rancière étudie les formes d’accompagnement entre images et mots, et pense la figurabilité comme articulation de deux pouvoirs expressifs en un agencement spécifique. Pour échapper au débat stérile sur la préséance de l’image sur le langage (ou vice-versa), on envisagera avec Rancière l’idée selon laquelle l’image serait une « manière dont les choses parlent et se taisent ». L’image ne dit pas mieux les intensités que les mots, mais elle aménage un lieu inédit pour la mise en fiction des paroles de l’histoire. En ce sens spécifique, la figurabilité, comme mise en scène des mots et des images, doit pouvoir compter sur le travail de l’indétermination – comme on le montrera avec quelques exemples cinématographiques. [less ▲]

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See detailElektrodynamische Fragmentierung von Elektroschrott
Iseli, Cédric; Streicher-Porte, Martin; Martino, Rémi ULg et al

Poster (2016, November 11)

Untersuchungen dazu werden in diesem Bericht am Beispiel von WEEE und speziell an Leiter-platten aufgezeigt. Die Versuche zeigen, dass EDF für verschiedenste Arten von Elektroschrott eingesetzt werden ... [more ▼]

Untersuchungen dazu werden in diesem Bericht am Beispiel von WEEE und speziell an Leiter-platten aufgezeigt. Die Versuche zeigen, dass EDF für verschiedenste Arten von Elektroschrott eingesetzt werden kann. Verschweisste Kompaktgeräte können zum Beispiel so weit geöffnet werden, dass die ge-wünschte Komponente freigelegt und entfernt werden kann. Leiterplatten haben die Eigenschaft, dass bei kontinuierlich steigendem Energieeintrag zuerst die aufgebrachten Komponenten abgetrennt werden, bevor die Cu-Bahnen freigelegt werden. Bei noch höherem Energieeintrag wird die Leiterplatte schlussendlich zerkleinert und vollständig zer-stört. Durch diese Entfrachtung der Leiterplatte kann ein metallreiches Konzentrat hergestellt werden. [less ▲]

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See detail3D and stereoscopy
Verly, Jacques ULg; Grogna, David ULg; Lejeune, Antoine ULg

Conference given outside the academic context (2016)

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See detailTraining researchers to ethics in research
Halleux, Isabelle ULg

Learning material (2016)

This document is provided as a support for training researchers on Ethical Decision Making, and Ethics and Quality in Research. It was presented to the Re@WBC meeting in Kragujevac, Serbia. It can be used ... [more ▼]

This document is provided as a support for training researchers on Ethical Decision Making, and Ethics and Quality in Research. It was presented to the Re@WBC meeting in Kragujevac, Serbia. It can be used in a "train the trainer" context. Duration: 1 day. A very active participation is expected from participants. [less ▲]

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See detailE-health y sus implicaciones jurídicas: el marco europeo e italiano
Colussi, Ilaria Anna ULg

Scientific conference (2016, November 11)

The conference focused on the right to health and its legal and ethical implications. The speech gave a framework on health policies in the European Union, and in particular on the use of technologies for ... [more ▼]

The conference focused on the right to health and its legal and ethical implications. The speech gave a framework on health policies in the European Union, and in particular on the use of technologies for health reasons. The Italian framework is also considered, in order to check the implementation of EU policies inside one National State and develop comparative analysis at that regard. [less ▲]

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See detailLeibniz and the Polyp, or the Metaphysical Puzzle of Life
Dony, Arthur ULg

Conference (2016, November 11)

In this paper, I propose to explore the link between experience and reason in the problem of the apprehension of life. My general claim is that philosophical issues are necessarily involved in a theory of ... [more ▼]

In this paper, I propose to explore the link between experience and reason in the problem of the apprehension of life. My general claim is that philosophical issues are necessarily involved in a theory of living organisms, since identifying a certain entity as a living being is to go beyond its manifestations. In part I, I argue that the empirical approach of the natural sciences cannot fully account for the peculiarity of life. In particular, I argue that the different criteria used to distinguish the living from the non-living, as those proposed in biology, are inadequate, both de facto and de jure. Indeed, they are constantly challenged by inventions of machines displaying features commonly regarded as specific to livings, and also by discoveries of new organisms whose unexpected features overcome the boundaries of our categories. More fundamentally, I hold that these criteria fail to provide sufficient conditions for qualifying beings as living, as long as the external appearances of life can, in principle, be reproduced by lifeless automatons. Therefore the phenomenological aspect of life, which cannot be accessed in a third person point of view (as the perception itself), turns out to be crucial. In the second part, I elaborate on these issues by focusing on the leibnizian theory of living beings. According to Leibniz, the distinctive feature of life is to have of a real unity, which must be conceived as the one to be found in a perceiving soul. After a brief survey on the foundations of this theory, I will emphasize how Leibniz’s attempt to account for the true unity of living beings – as opposed to the accidental unity of non-living things – exemplifies the problematic relationship between the observable properties of organized matter and the inner (or metaphysical) properties of the living as such. In Leibniz’s case indeed, the lack of empirical evidence forces him to resort to philosophical postulates, namely the principle of analogy and the principle of continuity. This latter principle allows him to qualify plants as living beings and to predict the existence of “borderline” organisms as the polyp. Finally, I will propose to consider the discovery of the polyp in the eighteenth century as a case of particular interest and a challenge to the classical conceptions of the living. Among its numerous outstanding properties, the polyp has the faculty to regenerate when cut into pieces, each of them becoming a whole new organism, and to breed by budding. Moreover, a polyp is constituted as a colony of self-contained, smaller polyps. Because of that, it is difficult to determine what the living organism exactly is: is it the colony as a whole or each of its members? And if the whole constitutes a real organism, how shall we explain its oneness? These issues raise the crucial questions of unity and individuality, which are of tremendous importance with regard to the ontological status of life. [less ▲]

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See detailReducing the global burden of HTLV-1 infection: An agenda for research and action
Willems, Luc ULg; Hasegawa, Hideki; Accolla, Roberto et al

in Antiviral Research (2016), 137(2017), 41-48

Even though an estimated 10e20 million people worldwide are infected with the oncogenic retrovirus, human T-lymphotropic virus type 1 (HTLV-1), its epidemiology is poorly understood, and little effort has ... [more ▼]

Even though an estimated 10e20 million people worldwide are infected with the oncogenic retrovirus, human T-lymphotropic virus type 1 (HTLV-1), its epidemiology is poorly understood, and little effort has been made to reduce its prevalence. In response to this situation, the Global Virus Network launched a taskforce in 2014 to develop new methods of prevention and treatment of HTLV-1 infection and promote basic research. HTLV-1 is the etiological agent of two life-threatening diseases, adult T-cell leukemia and HTLV-associated myelopathy/tropical spastic paraparesis, for which no effective therapy is currently available. Although the modes of transmission of HTLV-1 resemble those of the more familiar HIV-1, routine diagnostic methods are generally unavailable to support the prevention of new infections. In the present article, the Taskforce proposes a series of actions to expand epidemiological studies; increase research on mechanisms of HTLV-1 persistence, replication and pathogenesis; discover effective treatments; and develop prophylactic and therapeutic vaccines. [less ▲]

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See detail8ème Cours de Mécanique Analytique II (2016-17), Bac3 phys, Master 1 Sc. Sp.
Surdej, Jean ULg

Learning material (2016)

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Peer Reviewed
See detail两种挥发性化学信息素与小麦-豌豆间作协同作用
Xu, Qingxuan ULg; Chevalier Mendes Lopes, Thomas ULg; Hatt, Séverin ULg et al

Conference (2016, November 10)

当今的害虫防治理念已从传统的“杀灭”转向科学的“调控”,生态调控成为可持续农业领域中的研究热点之一。间作提高农作物的多样性是作物虫害生态调控途径之一,间作作物导致农田生物多样性增加、为天敌昆虫提供食物和避难所,从而使天敌种类和数量增加,为目标害虫控治作用增强。已有结果表明小麦与豌豆间作、混作,不仅有效降低小麦上麦长管蚜的种群数量,增加了天敌控制害虫的稳定性和持续性, ... [more ▼]

当今的害虫防治理念已从传统的“杀灭”转向科学的“调控”,生态调控成为可持续农业领域中的研究热点之一。间作提高农作物的多样性是作物虫害生态调控途径之一,间作作物导致农田生物多样性增加、为天敌昆虫提供食物和避难所,从而使天敌种类和数量增加,为目标害虫控治作用增强。已有结果表明小麦与豌豆间作、混作,不仅有效降低小麦上麦长管蚜的种群数量,增加了天敌控制害虫的稳定性和持续性, 而且可以增产保收、养地改土。一些昆虫取食诱导的挥发物和昆虫自身分泌物(如水杨酸甲酯MeSA、蚜虫报警信息素EBF)具有驱避蚜虫对植食性昆虫进行行为调控的直接防御,还可以通过吸引第三级营养级的天敌昆虫,提升间接防御害虫作用。 为了探索作物间作与行为调控挥发物的协同的控害效果,本研究采用小麦间作豌豆、协同化学信息素(MeSA、EBF)的释放,于比利时Gembloux地区连续两年(2015年3月-8月年和2016年3月-8月)进行田间实验。结果表明与单纯小麦-豌豆间作相比,小麦-豌豆间作配合EBF、MeSA的释放,提高了蚜茧蜂对豌豆蚜的寄生率,对蚜虫天敌草蛉、食蚜蝇、瓢虫也具有强烈的吸引作用,豌豆蚜及麦蚜的无翅蚜田间发生量分别降低达35%和30%。 间作的豌豆可以为天敌提供栖居和食物,有利于蚜虫天敌的繁殖,而豌豆蚜的发生峰期早于麦蚜发生峰期一周左右,因此间作结合挥发物的释放,更有利于豌豆田中的蚜虫主要天敌最大程度的转移到麦田中防控麦蚜,有效降低麦蚜发生峰期的种群数量,两种方法组合构成“吸引-补偿”(Attract–Reward)的机制,将挥发物行为调控与栖境管理两种防控害虫的方法有效的结合起来,进一步增强生防效果,有助于建立综合的小麦害虫绿色防控体系。 [less ▲]

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See detailDécider ensemble ou vivre ensemble?
Bouhon, Frédéric ULg

Scientific conference (2016, November 10)

Ce discours constitue la "leçon inaugurale" prononcée par l'auteur, selon la tradition de la Faculté de Droit, de Science politique et de Criminologie de Liège. L'exposé porte sur les notions de ... [more ▼]

Ce discours constitue la "leçon inaugurale" prononcée par l'auteur, selon la tradition de la Faculté de Droit, de Science politique et de Criminologie de Liège. L'exposé porte sur les notions de démocratie et de droits fondamentaux. À travers quelques questions choisies, l'auteur cherche à rappeler qu'il s'agit de concepts bien distincts, qui connaissent toutefois des interactions nombreuses. [less ▲]

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See detailMalachite and heterogenite behavior during the locked-cycle recycling of process water in flotation of copper-cobalt oxide ores
Shengo, Michel; Gaydardzhiev, Stoyan ULg; Kalenga, Pierre

in International Journal of Mineral Processing (2016), 157

The behavior of malachite and heterogenite was investigated during the process water recycling in flotation of copper-cobalt oxide ores from the deposit of Luiswishi located in Haut-Katanga province (DRC ... [more ▼]

The behavior of malachite and heterogenite was investigated during the process water recycling in flotation of copper-cobalt oxide ores from the deposit of Luiswishi located in Haut-Katanga province (DRC). A synthetic mill wastewater (SMWW) was utilized as feed water alone and in mixture with water recovered from the flotation tails in view to achieve at the laboratory scale the locked-cycle recycling of the industrial mill wastewater (IMWW). To simulate the chemical species presence in the pulp and their effects on the flotation of malachite and heterogenite, calcium, magnesium and bicarbonate ions were added to the feed water and the recoveries of copper and cobalt followed during the roughing flotation stage. The concentrate XRD and SEM analysis together with the floated minerals microanalyses by EDX spectroscopy, leaching tests of mono-minerals followed by the Pourbaix diagrams construction and DRIFT spectroscopy analyses, have enabled identifying changes in the surface properties of malachite and heterogenite interfering on the recovery of copper (40 %) and cobalt (58 %) with a significant drop in their concentrate grades (7.3 % Cu and 2.7 % Co). The deterioration of the concentrate characteristics results also from the gangue minerals entrainment. A better description of the valuable minerals behaviour in the SMWW presence could enable designing strategies in view enhancing their floatability during the locked-cycle recycling of water. [less ▲]

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See detailPouvoir politique et audace des juges
Grandjean, Geoffrey ULg

Scientific conference (2016, November 10)

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See detailLong-term care social insurance. How to avoid big losses?
Klimaviciute, Justina ULg; Pestieau, Pierre ULg

Scientific conference (2016, November 10)

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See detailArt, musique et intégration des réfugiés. Le cas de Naples en Italie
Mazzola, Alessandro ULg

Conference given outside the academic context (2016)

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See detailAudition au Parlement wallon sur la possibilité juridique d'interdire aux fonctionnaires locaux en contact avec le public le port de signes convictionnels ostentatoires
Behrendt, Christian ULg

Report (2016)

Audition comme expert par la Commission des pouvoirs locaux, du logement et de l'énergie du Parlement wallon, Namur, Parlement wallon, 10 novembre 2016.

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See detailA Model of Endogenous Insulin Secretion During Exercise
Thomas, Felicity Louise ULg

Poster (2016, November 10)

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See detailMyoferlin is a novel exosomal protein and functional regulator of cancer-derived exosomes
Blomme, Arnaud; Fahmy, Karim; Peulen, Olivier ULg et al

in Oncotarget (2016)

Exosomes are communication mediators participating in the intercellular exchange of proteins, metabolites and nucleic acids. Recent studies have demonstrated that exosomes are characterized by a unique ... [more ▼]

Exosomes are communication mediators participating in the intercellular exchange of proteins, metabolites and nucleic acids. Recent studies have demonstrated that exosomes are characterized by a unique proteomic composition that is distinct from the cellular one. The mechanisms responsible for determining the proteome content of the exosomes remain however obscure. In the current study we employ ultrastructural approach to validate a novel exosomal protein myoferlin. This is a multiple C2-domain containing protein, known for its conserved physiological function in endocytosis and vesicle fusion biology. Emerging studies demonstrate that myoferlin is frequently overexpressed in cancer, where it promotes cancer cell migration and invasion. Our data expand these ndings by showing that myoferlin is a general component of cancer cell derived exosomes from different breast and pancreatic cancer cell lines. Using proteomic analysis, we demonstrate for the rst time that myoferlin depletion in cancer cells leads to a signi cantly modulated exosomal protein load. Such myoferlin-depleted exosomes were also functionally de cient as shown by their reduced capacity to transfer nucleic acids to human endothelial cells (HUVEC). Beyond this, myoferlin-depleted cancer exosomes also had a signi cantly reduced ability to induce migration and proliferation of HUVEC. The present study highlights myoferlin as a new functional player in exosome biology, calling for novel strategies to target this emerging oncogene in human cancer. [less ▲]

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See detailL'optique spatiale en Wallonie: de la génèse aux développements récents
Georges, Marc ULg; Denis, Stefan; Joannes, Luc

Scientific conference (2016, November 10)

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