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See detailProcédure pénale
Michiels, Olivier ULg; Falque, Géraldine ULg

Learning material (2015)

Syllabus du cours de procédure pénale pour l'année académique 2014-2015

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See detailReverse current transient behavior of pGeSn/nGe diodes
Baert, Bruno ULg; Gupta, Somya; Gencarelli, Federica et al

Conference (2015)

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See detailVehicle routing problems with loading constraints: State-of-the-art and future directions
Pollaris, Hanne; Braekers, Kris; Caris, An et al

in OR Spectrum (2015), 37(Issue 2), 297-330

Distributors are faced with loading constraints in their route planning, e.g.,multi-dimensional packing constraints, unloading sequence constraints, stability constraints and axle weight limits. Ignoring ... [more ▼]

Distributors are faced with loading constraints in their route planning, e.g.,multi-dimensional packing constraints, unloading sequence constraints, stability constraints and axle weight limits. Ignoring these constraints impairs planning and induces last-minute changes resulting in additional costs. Developing vehicle routing models incorporating loading constraints is critical to more efficient route planning. The last couple of years has seen a huge increase of contributions to this field of research with almost 60 % of these being published after 2009. Our contribution is twofold. First, we overview the recent developments in the literature on all vehicle types in which loading constraints play a key role (trucks, airplanes, ships, and automated guided vehicles), using a state-of-the-art classification scheme to identify the loading constraints considered in each article. Second, we identify research gaps and opportunities for future research. [less ▲]

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See detailA Systematic Review of Cost-Effectiveness Analyses of Drugs for Postmenopausal Osteoporosis.
Hiligsmann, Mickaël ULg; Evers, Silvia M.; Ben Sedrine, Wafa et al

in PharmacoEconomics (2015), 33(3), 205-224

BACKGROUND: Given the limited availability of healthcare resources and the recent introduction of new anti-osteoporosis drugs, the interest in the cost effectiveness of drugs in postmenopausal ... [more ▼]

BACKGROUND: Given the limited availability of healthcare resources and the recent introduction of new anti-osteoporosis drugs, the interest in the cost effectiveness of drugs in postmenopausal osteoporosis remains and even increases. OBJECTIVE: This study aims to identify all recent economic evaluations on drugs for postmenopausal osteoporosis, to critically appraise the reporting quality, and to summarize the results. METHODS: A literature search using Medline, the National Health Service Economic Evaluation database and the Cost-Effectiveness Analysis Registry was undertaken to identify original articles published between January 1, 2008 and December 31, 2013. Studies that assessed cost effectiveness of drugs in postmenopausal osteoporosis were included. The Consolidated Health Economic Evaluation Reporting Standards (CHEERS) statement was used to assess the quality of reporting of these articles. RESULTS: Of 1,794 articles identified, 39 studies fulfilled the inclusion criteria. They were conducted in 14 different countries and nine active interventions were assessed. When compared with no treatment, active osteoporotic drugs were generally cost effective in postmenopausal women aged over 60-65 years with low bone mass, especially those with prior vertebral fractures. Key drivers of cost effectiveness included individual fracture risk, medication adherence, selected comparators and country-specific analyses. Quality of reporting varied between studies with an average score of 17.9 out of 24 (range 7-21.5). CONCLUSION: This review found a substantial number of published cost-effectiveness analyses of drugs in osteoporosis in the last 6 years. Results and critical appraisal of these articles can help decision makers when prioritizing health interventions and can inform the development of future economic evaluations. [less ▲]

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See detailTest-positive rate at CT colonography is increased by rectal bleeding and/orunexplained weight loss, unlike other common gastrointestinal symptoms
Hock, Danielle; MATERNE, Roland; Ouhadi, Roxanne et al

in European Journal of Radiology (2015), 2

2015AbstractPurpose: We evaluated the rate of significant colonic and extra-colonic abnormalities at computed tomography colonography (CTC), accordingto symptoms and age.Materials and methods: We ... [more ▼]

2015AbstractPurpose: We evaluated the rate of significant colonic and extra-colonic abnormalities at computed tomography colonography (CTC), accordingto symptoms and age.Materials and methods: We retrospectively evaluated 7361 consecutive average-risk subjects (3073 males, average age: 60.3 ± 13.9; range 18–96years) for colorectal cancer (CRC) who underwent CTC. They were divided into three groups according to clinical symptoms: 1343 asymptomaticindividuals (group A), 899 patients with at least one “alarm” symptom for CRC, including rectal bleeding and unexplained weight loss (groupC), and 5119 subjects with other gastrointestinal symptoms (group B). Diagnostic and test-positive rates of CTC were established using opticalcolonoscopy (OC) and/or surgery as reference standard. In addition, clinically significant extra-colonic findings were noted.Results: 903 out of 7361 (12%, 95% confidence interval (CI) 0.11–0.13) subjects had at least one clinically significant colonic finding at CTC. CTCtrue positive fraction and false positive fraction were respectively 637/642 (99.2%, 95%CI 0.98–0.99) and 55/692 (7.95%, 95%CI 0.05–0.09). Thepooled test-positive rate in group C (138/689, 20.0%, 95%CI 0.17–0.23) was significantly higher than in both groups A (79/1343, 5.9%, 95%CI0.04–0.07) and B (420/5329, 7.5%, 95%CI 0.07–0.08) (p < 0.001). Aging and male gender were associated to a higher test positive rate. The rateof clinically significant extra-colonic findings was significantly higher in group C (44/689, 6.4%, 95%CI 0.04–0.08) versus groups A (26/1343,1.9%, 95%CI 0.01–0.02) and B (64/5329, 1.2%, 95%CI 0.01–0.02) (p < 0.001).Conclusion: Both test-positive and significant extra-colonic finding rates at CTC are significantly increased in the presence of “alarm” gastroin-testinal symptoms especially in older patients. [less ▲]

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See detailRapport annuel doctorat 2014-2015
Dechene, Antoine ULg

Report (2015)

Rapport de thèse de doctorat

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See detailÉvaluation technico-économique de la production de plants de teck (Tectona grandis L.f.) dans les pépinières villageoises au Sud-Bénin
Séhouéto, Caroline K. P.; Aoudji, Augustin K. N.; Avocèvou-Ayisso, Carolle et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2015), 19(1), 32-41

The present study deals with the production of the seedlings of teak (Tectona grandis L.f.), a species used in forest plantations in southern Benin. The aim of the study was to evaluate the techniques and ... [more ▼]

The present study deals with the production of the seedlings of teak (Tectona grandis L.f.), a species used in forest plantations in southern Benin. The aim of the study was to evaluate the techniques and the profitability of teak seedling production in the community nurseries of southern Benin. [less ▲]

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See detailLe Journal d’Antoine Galland (1646-1715) : la période parisienne. Volume IV (1714-1715)
Bauden, Frédéric ULg; Waller, Richard; Veymiers, Richard ULg et al

Book published by Peeters (2015)

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See detailA Lower Tournaisian (Hastarian) silicified brachiopod-coral fauna from South Belgium
Denayer, Julien ULg; Mottequin, Bernard; Poty, Edouard

Conference (2015)

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See detailNon-myeloablative allogeneic hematopoietic cell transplantation following fludarabine plus 2 Gy TBI or ATG plus 8 Gy TLI: a phase II randomized study from the Belgian Hematological Society
Baron, Frédéric ULg; Zachée, Pierre; Maertens, Johan et al

in Journal of Hematology & Oncology (2015), 8(4), 10118613045-014-0098-9

Background: Few studies thus far have compared head-to-head different non-myelooablative conditioning regimens for allogeneic hematopoietic cell transplantation (allo-HCT). Methods: Here, we report the ... [more ▼]

Background: Few studies thus far have compared head-to-head different non-myelooablative conditioning regimens for allogeneic hematopoietic cell transplantation (allo-HCT). Methods: Here, we report the results of a phase II multicenter randomized study comparing non-myeloablative allo-HCT from HLA-identical siblings (n = 54) or from 10/10 HLA-matched unrelated donors (n = 40) with either fludarabine plus 2 Gy total body irradiation (Flu-TBI arm; n = 49) or 8 Gy TLI + anti-thymocyte globulin (TLI-ATG arm; n = 45) conditioning. Results: The 180-day cumulative incidences of grade II-IV acute GVHD (primary endpoint) were 12.2% versus 8.9% in Flu-TBI and TLI-ATG patients, respectively (P = 0.5). Two-year cumulative incidences of moderate/severe chronic GVHD were 40.8% versus 17.8% in Flu-TBI and TLI-ATG patients, respectively (P = 0.017). Five Flu-TBI patients and 10 TLI-ATG patients received pre-emptive DLI for low donor chimerism levels, while 1 Flu-TBI patient and 5 TLI-ATG patients (including 2 patients given prior pre-emptive DLIs) received a second HCT for poor graft function, graft rejection, or disease progression. Four-year cumulative incidences of relapse/progression were 22% and 50% in Flu-TBI and TLI-ATG patients, respectively (P = 0.017). Four-year cumulative incidences of nonrelapse mortality were 24% and 13% in Flu-TBI and TLI-ATG patients, respectively (P = 0.5). Finally, 4-year overall (OS) and progression-free survivals (PFS) were 53% and 54%, respectively, in the Flu-TBI arm, versus 54% (P = 0.9) and 37% (P = 0.12), respectively, in the TLI-ATG arm. Conclusions: In comparison to patients included in the Flu-TBI arm, patients included in the TLI-ATG arm had lower incidence of chronic GVHD, higher incidence of relapse and similar OS. [less ▲]

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See detailSeasonal changes in the neuroendocrine system: Introduction to the special issue.
Ball, Gregory F.; Balthazart, Jacques ULg

in Frontiers in neuroendocrinology (2015), 37

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See detailMale song quality modulates c-Fos expression in the auditory forebrain of the female canary.
Monbureau, Marie; Barker, Jennifer M.; Leboucher, Gerard et al

in Physiology & behavior (2015), 147

In canaries, specific phrases of male song (sexy songs, SS) that are difficult to produce are especially attractive for females. Females exposed to SS produce more copulation displays and deposit more ... [more ▼]

In canaries, specific phrases of male song (sexy songs, SS) that are difficult to produce are especially attractive for females. Females exposed to SS produce more copulation displays and deposit more testosterone into their eggs than females exposed to non-sexy songs (NS). Increased expression of the immediate early genes c-Fos or zenk (a.k.a. egr-1) has been observed in the auditory forebrain of female songbirds hearing attractive songs. C-Fos immunoreactive (Fos-ir) cell numbers were quantified here in the brain of female canaries that had been collected 30min after they had been exposed for 60min to the playback of SS or NS or control white noise. Fos-ir cell numbers increased in the caudomedial mesopallium (CMM) and caudomedial nidopallium (NCM) of SS birds as compared to controls. Song playback (pooled SS and NS) also tended to increase average Fos-ir cell numbers in the mediobasal hypothalamus (MBH) but this effect did not reach full statistical significance. At the individual level, Fos expression in CMM was correlated with its expression in NCM and in MBH but also with the frequency of calls that females produced in response to the playbacks. These data thus indicate that male songs of different qualities induce a differential metabolic activation of NCM and CMM. The correlation between activation of auditory regions and of the MBH might reflect the link between auditory stimulation and changes in behavior and reproductive physiology. [less ▲]

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See detailLe témoignage comme structure d’expression pour le théâtre-action, étude de cas : Royal Boch, la dernière défaïence
Brahy, Rachel ULg; Ieven, Emilie

in Quillet, Françoise (Ed.) La scène mondiale aujourd'hui. Des formes en mouvement (2015)

Depuis quelques années, nous constatons la présence significative des témoins et témoignages au sein du théâtre et ce, quelle que soit la forme que celui-ci prend. Le théâtre-action, théâtre participatif ... [more ▼]

Depuis quelques années, nous constatons la présence significative des témoins et témoignages au sein du théâtre et ce, quelle que soit la forme que celui-ci prend. Le théâtre-action, théâtre participatif et engagé, a recours depuis son origine à d’authentiques témoins dans certaines de ses productions. A la fois sujets et comédiens des événements qu’ils ont vécus, ces témoins possèdent un statut particulier, paradoxal du fait qu’ils entremêlent des logiques a priori contradictoires : la logique de vécu et la logique fictionnelle. La mise en tension de ces deux logiques apparait comme un nœud fécond suscitant de nombreuses interrogations. Confrontant la théorie à un cas pratique (l’étude de la pièce Royal Boch, la dernière défaïence), le présent article propose de mettre en lumière la dimension politique du témoin au sein d’une pièce de théâtre-action. Après avoir dressé un bref panorama informatif de l’histoire du théâtre-action, nous présenterons – dans un premier temps - notre étude de cas, Royal Boch, la dernière défaïence. Dans un deuxième temps, la réflexion se concentrera sur la structure du témoignage et sa mise en pratique au sein de la pièce Royal Boch. Dans un troisième temps, l’article problématisera, sous l’angle de l’authenticité, la relation entre témoignages/témoins et la dimension fictionnelle inhérente à toute pièce théâtrale. Sur base des différents éléments analysés, la réflexion mettra en exergue l’efficacité politique de la figure du témoin dans le théâtre-action. [less ▲]

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See detailChemical composition and functional properties of dietary fibre extracted by Englyst and Prosky methods from the alga Ulva lactuca collected in Tunisia
Yaich, Hela; Garna, Haikel; Bchir, Brahim et al

in Algal Research (2015), 9

Nowadays there is a growing trend to find new sources of dietary fibre (DF), such as marine algae by-products that have traditionally been undervalued. In this respect, the aim of the present ... [more ▼]

Nowadays there is a growing trend to find new sources of dietary fibre (DF), such as marine algae by-products that have traditionally been undervalued. In this respect, the aim of the present investigation was firstly to compare two methods of dietary fibre quantification (Englyst and Prosky) and secondly to determine the chemical composition and some of the functional properties of total and insoluble fibres extracted in accordance with the Englyst method. The dietary fibres of dried Ulva lactuca collected from the Tunisian littoral were determined by the Prosky (gravimetric method) and Englyst (enzymatic-chemical method) methods. The two extraction methods (Englyst–Prosky) provided approximately the same values in total fibres (~54%). However, they had different insoluble and soluble fibre contents. U. lactuca contained 20.53% and 31.55% of soluble fibres and 34.37% and 21.54% of insoluble fibres using the Prosky and Englyst methods, respectively. The fractionation of the insoluble dietary fibre concentrate revealed that hemicellulose was the most abundant fraction (32.49%), followed by cellulose (16.59%) and “lignin-like” compounds (1.53%). For both fibre concentrates, the main neutral sugar was glucose (20.70%–27.59%), which corresponded to hemicellulose and cellulose. The water holding capacity of insoluble fibre concentrate was relatively high. It varied between 9.32 g and 10.3 g of water/g of dry fibre at 25 °C and 80 °C, respectively. Nevertheless, the oil holding capacity of the insoluble fibre concentrate was not affected by temperature. It was about 1.08 and 1.01 g of oil/g of dry fibre at 25 °C and 80 °C. Despite the significant functional properties of fibre concentrate, the presence of lead limits its use as an ingredient in the food industry. [less ▲]

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See detailSoil redistribution and weathering controlling the fate of geochemical and physical carbon stabilization mechanisms in soils of an eroding landscape
Doetterl, Sebastien; Six, Johan; Bodé, Samuel et al

in Biogeosciences (2015)

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See detailNylon flocked swab severely reduces Hexagon Obti sensibility
Frippiat, Christophe; De Roy, Gilbert; Fontaine, Louis-Marie et al

in Forensic Science International (2015), 247(0), 126-129

Abstract Hexagon Obti immunological blood test and flocked swab are widely used in forensic laboratories. Nevertheless, up to now, no compatibility tests have been published between sampling with the ... [more ▼]

Abstract Hexagon Obti immunological blood test and flocked swab are widely used in forensic laboratories. Nevertheless, up to now, no compatibility tests have been published between sampling with the ethylene oxide treated flocked swab and the Hexagon Obti blood detection strip. In this study, we investigated this compatibility. Our work shows that sampling with ethylene oxide treated flocked swab reduces by a factor of at least 100 the detection threshold of blood using the Hexagon Obti immunological test. [less ▲]

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See detailNotions de pharmacologie
Kaux, Jean-François ULg

Learning material (2015)

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See detailMorphological details in bloodstain particles
De Wael, Kris; Lepot, Laurent ULg

in Forensic Science International (2015), 246(0), 50-54

Abstract During the commission of crimes blood can be transferred to the clothing of the offender or on other crime related objects. Bloodstain particles are sub-millimetre sized flakes that are lost from ... [more ▼]

Abstract During the commission of crimes blood can be transferred to the clothing of the offender or on other crime related objects. Bloodstain particles are sub-millimetre sized flakes that are lost from dried bloodstains. The nature of these red particles is easily confirmed using spectroscopic methods. In casework, bloodstain particles showing highly detailed morphological features were observed. These provided a rationale for a series of experiments described in this work. It was found that the “largest” particles are shed from blood deposited on polyester and polyamide woven fabrics. No particles are lost from the stains made on absorbent fabrics and from those made on knitted fabrics. The morphological features observed in bloodstain particles can provide important information on the substrates from which they were lost. [less ▲]

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