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See detailLes intercommunales et les impôts sur les revenus : une valse fiscale à deux temps
Garroy, Sabine ULg

in ASBL Actualités (2017)

En 2014 et 2015, le régime fiscal des intercommunales a été revu de manière substantielle. Nous nous proposons, après une première section consacrée au cadre légal dans lequel cette réforme s’inscrit (I ... [more ▼]

En 2014 et 2015, le régime fiscal des intercommunales a été revu de manière substantielle. Nous nous proposons, après une première section consacrée au cadre légal dans lequel cette réforme s’inscrit (I), de décrire les grandes lignes de cette réforme suivant le rythme d’une valse à deux temps (II) ainsi que de livrer un bref commentaire de la circulaire administrative 10/2016 à l’occasion duquel nous nous interrogerons sur les éventuelles implications de cette réforme sur des personnes morales relevant du droit privé, les associations sans but lucratif (ci-après : ASBL) notamment (III). [less ▲]

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See detailMaking Sense Out of Pulsating Pre-ELM and ELM White Dwarfs
Fontaine, Gilles; Istrate, Alina; Gianninas, Alexandros et al

in Astronomical Society of the Pacific Conference Series (2017), 509

We present a unified view of pulsations in both pre-ELM and ELM white dwarfs within the framework of state-of-the-art binary evolution calculations that take into account the combined effects of diffusion ... [more ▼]

We present a unified view of pulsations in both pre-ELM and ELM white dwarfs within the framework of state-of-the-art binary evolution calculations that take into account the combined effects of diffusion and rotational mixing. We find that rotational mixing is able to maintain against settling a sufficient amount of helium in the envelope in order to fuel pulsations through He II-He III ionization on the pre-ELM branch of the evolutionary track in the spectroscopic HR diagram. By the time such a low-mass white dwarf enters the ZZ Ceti instability strip on the cooling branch, settling has taken over rotational mixing and produced a pure H envelope. Such a star then pulsates again, but, this time, as a DA white dwarf of the ZZ Ceti type. [less ▲]

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See detailContribution of past and future self-defining event networks to personal identity
Demblon, Julie; D'Argembeau, Arnaud ULg

in Memory (2017), 25

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See detailDeprivation of citizenship for 'jihadists' Analysis of Belgian and French practice and policy in light of the principle of equal treatment
Wautelet, Patrick ULg

in Kruiniger, Pauline (Ed.) Jihad, Islam en Recht. Jihadisme en reacties vanuit het Nederlandse en Belgische recht (2017)

In the fight against terrorism States have resorted to a variety of weapons. Much attention has been devoted to criminal law as a possible answer to terrorism. Many States have also resorted to ... [more ▼]

In the fight against terrorism States have resorted to a variety of weapons. Much attention has been devoted to criminal law as a possible answer to terrorism. Many States have also resorted to nationality law, using deprivation as a means to punish those involved in terrorism. This paper will focus on Belgium and France. These two countries indeed present striking similarities. Both in France and Belgium the provisions on deprivation already made it possible to deprive a national of his citizenship in terrorist cases. Nevertheless, the legislation in these countries has been recently modified to offer yet a stronger answer to terrorism. The public debate in the two countries is modelled on similar lines. This is in particular true for the issue of equality arising in connection of deprivation of nationality. The paper will first offer an overview of the existing statutory provisions in the two countries, before critically reviewing the discussion on equality and non discrimination. [less ▲]

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See detailPhotoreversibility and biocompatibility of polydimethylsiloxane-coumarin as adjustable intraocular lens material
Jellali, Rachid; Bertrand, Virginie ULg; Alexandre, Michaël et al

in Macromolecular Bioscience (2017)

Polydimethylsiloxane (PDMS) constitutes an interesting material for a variety of biomed- ical applications, especially as intraocular lenses (IOLs), for its excellent transparency. In this work, a ... [more ▼]

Polydimethylsiloxane (PDMS) constitutes an interesting material for a variety of biomed- ical applications, especially as intraocular lenses (IOLs), for its excellent transparency. In this work, a photoreversible PDMS-coumarin network, whose shape and properties can be adjusted postoperatively in a noninvasive manner, is developed. The synthesis of PDMS-cou- marin is achieved by amidation of a coumarin acid chloride derivative with amine-function- alized PDMSs. Under exposure of λ > 300 nm, these polymers can be cured by dimerization of coumarin. The cured polymers can be uncrosslinked via photocleavage of cyclobutane dimers upon illumination at λ < 290 nm. The diffusion of linear PDMSs in a crosslinked network and the controlled shape modification are studied, which demonstrate that these polymers are good candidates for adjustable IOL application. IOL disks prepared from these materials show high hydrophobicity and good transparency. In vitro cytotoxicity, lens epithelial cell adhesion assays, and rabbit host reaction against implanted disks demonstrate the biocompatibility of the polymer. [less ▲]

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See detailDiscriminations "ethno-raciales": comprendre, pour agir dans la relation d'aide?
Collin, Jonathan ULg

Scientific conference (2017)

Cette conférence a d'abord examiné l'évolution sémantique observée - du racisme aux discriminations - et la manière de concevoir l'adjectif "ethno-raciales" que j'y associe. Quelques données chiffrées ... [more ▼]

Cette conférence a d'abord examiné l'évolution sémantique observée - du racisme aux discriminations - et la manière de concevoir l'adjectif "ethno-raciales" que j'y associe. Quelques données chiffrées relatives aux discriminations en Belgique et en Europe furent ensuite présentées. Enfin, une analyse en termes de gestion publique du stigmate et des interactions - interethniques - en face à face (Erving Goffman notamment) fut proposée. [less ▲]

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See detailUne mobilité résidentielle durable est-elle possible ? Pratiques de déplacements, modèles urbains et choix de localisation de populations résidentes en Wallonie
Reiter, Sigrid ULg; Ghiezen, Sébastien; Pierson, Charlotte

in Negron-Poblete, Paula; Paulhiac Scherrer, Florence (Eds.) Villes à vivre. Le quotidien métropolitain entre ancrage et mobilité. (2017)

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See detailDulaglutide for the treatment of type 2 diabetes.
Scheen, André ULg

in Expert Opinion on Biological Therapy (2017), 17(4), 485-496

INTRODUCTION: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are injectable agents used for the treatment of hyperglycemia in type 2 diabetes. The interest for this pharmacological class is rising ... [more ▼]

INTRODUCTION: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are injectable agents used for the treatment of hyperglycemia in type 2 diabetes. The interest for this pharmacological class is rising with the development of once weekly compounds and the demonstration of a potential reduction in cardiorenal outcomes. Areas covered: The paper describes the main pharmacokinetic/pharmacodynamic characteristics of dulaglutide, a new once-weekly GLP-1 RA. Dulaglutide was extensively investigated in the phase-3 AWARD program, which demonstrated its safety and efficacy when compared to placebo or active glucose-lowering agents in patients treated with diet alone, metformin or sulfonylurea monotherapy, oral dual therapies and basal insulin. In both Caucasian and Japanese patients, comparative trials showed better glucose control with dulaglutide, with a minimal risk of hypoglycemia and weight loss, but at the expense of an increased dropout rate due to side effects, mostly transient gastrointestinal disturbances. Dulaglutide proved its non-inferiority versus liraglutide and the safety and tolerance profile is similar to that of other GLP-1 RAs. Expert opinion: The once-weekly formulation and the combined positive effects on both glucose control and weight improves patient satisfaction despite nausea. Dulaglutide must prove its capacity to reduce cardiovascular and diabetic complications in the ongoing prospective REWIND trial. [less ▲]

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See detailPharmacotherapy of 'treatment resistant' type 2 diabetes.
Scheen, André ULg

in Expert Opinion on Pharmacotherapy (2017), 1

INTRODUCTION: Despite type 2 diabetes (T2D) management offers a variety of pharmacological interventions targeting different defects, numerous patients remain with persistent hyperglycaemia responsible ... [more ▼]

INTRODUCTION: Despite type 2 diabetes (T2D) management offers a variety of pharmacological interventions targeting different defects, numerous patients remain with persistent hyperglycaemia responsible for severe complications. Unlike resistant hypertension, treatment resistant T2D is not a classical concept although it is a rather common observation in clinical practice. Areas covered: This article proposes a definition for 'treatment resistant diabetes', analyses the causes of poor glucose control despite standard therapy, briefly considers the alternative approaches to glucose-lowering pharmacotherapy and finally describes how to overcome poor glycaemic control, using innovative oral or injectable combination therapies. Expert opinion: Before considering intensifying the pharmacotherapy of a patient with poorly controlled T2D, it is important to verify treatment adherence, target obesity and consider various non pharmacological improvement quality interventions. If treatment resistant diabetes is defined as not achieving glycated haemoglobin target despite oral triple therapy with a third glucose-lowering agent added to metformin-sulfonylurea dual treatment, the combination of a dipeptidyl peptidase-4 (DPP-4) inhibitor and a sodium glucose cotransporter type 2 (SGLT2) inhibitor may offer new opportunities before considering injectable therapies. Insulin basal therapy (+/- metformin) may be optimized by the addition of a SGLT2 inhibitor or a glucagon-like peptide-1 (GLP-1) receptor agonist. [less ▲]

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See detailEffects of reducing blood pressure on renal outcomes in patients with type 2 diabetes: Focus on SGLT2 inhibitors and EMPA-REG OUTCOME.
Scheen, André ULg; Delanaye, P.

in Diabètes & Métabolism (2017), (epub ahead of print),

Empagliflozin, a sodium-glucose cotransporter type 2 (SGLT2) inhibitor, has enabled remarkable reductions in cardiovascular and all-cause mortality as well as in renal outcomes in patients with type 2 ... [more ▼]

Empagliflozin, a sodium-glucose cotransporter type 2 (SGLT2) inhibitor, has enabled remarkable reductions in cardiovascular and all-cause mortality as well as in renal outcomes in patients with type 2 diabetes (T2D) and a history of cardiovascular disease in the EMPA-REG OUTCOME. These results have been attributed to haemodynamic rather than metabolic effects, in part due to the osmotic/diuretic action of empagliflozin and the reduction in arterial blood pressure (BP). The present narrative review includes the results of meta-analyses of trials evaluating the effects on renal outcomes of lowering BP in patients with T2D, with a special focus on the influence of baseline and achieved systolic BP, and compares the renal outcome results of the EMPA-REG OUTCOME with those of other major trials with inhibitors of the renin-angiotensin system in patients with T2D and the preliminary findings with other SGLT2 inhibitors, and also evaluates post hoc analyses from the EMPA-REG OUTCOME of special interest as regards the BP-lowering hypothesis and renal function. While systemic BP reduction associated to empagliflozin therapy may have contributed to the renal benefits reported in EMPA-REG OUTCOME, other local mechanisms related to kidney homoeostasis most probably also played a role in the overall protection observed in the trial. [less ▲]

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See detailPreliminary assessment of the possibilities of the Particle Finite Element Method in the numerical simulation of bird impact on aeronautical structures
Cerquaglia, Marco Lucio ULg; Deliège, Geoffrey ULg; Boman, Romain ULg et al

in Procedia Engineering (2017), 173

As well known, in the analysis of bird impact events the bird is often reduced, even experimentally, to a surrogate projectile modeled as a weakly compressible fluid (typically a mixture of water and air ... [more ▼]

As well known, in the analysis of bird impact events the bird is often reduced, even experimentally, to a surrogate projectile modeled as a weakly compressible fluid (typically a mixture of water and air). From a numerical standpoint, the presence of a free surface and the strong interaction with the aircraft structures represent a limit for traditional computational fluid dynamics methods based on an Eulerian grid. On the other hand, classical Lagrangian methods cannot cope with the extremely large deformations experienced by the projectile during the impact. The Particle Finite Element Method (PFEM) is a Lagrangian particle method that can account for very large deformations, preserving the robustness and generality of the finite element method, and thus owning a key advantage over other approaches, e.g. Smoothed Particle Hydrodynamics (SPH), usually cursed with consistency and stability issues. To assess the possibilities of the method in the context of bird impact, theoretical analyses are initially performed based on the impact of a water jet on a rigid surface. Then, the influence of the geometry of a more realistic projectile is analyzed and the capability of the method to take into account separation and fragmentation is highlighted. [less ▲]

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See detailLong-term consistency of spatial patterns of primate seed dispersal
Heymann, E. W.; Culot, Laurence ULg; Knogge, Christoph et al

in Ecology and Evolution (2017)

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See detailPersistence of the effec of frugivore identity on post-dispersal seed fate: consequences for the assessment of functional redundancy
Lugon, Ana Paula; Boutefeu, Marion; Bovy, Emilie et al

in Biotropica (2017)

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See detailATLANTIC-FRUGIVORY: A PLANT-FRUGIVORE INTERACTION DATASET FOR THE ATLANTIC FOREST
Bello, C; Galetti, M; Montan, D et al

in Ecology (2017)

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