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See detailInteraction between dietary protein content and the source of carbohydrates along the gastrointestinal tract of weaned piglets.
Pieper, Robert; Boudry, Christelle ULg; Bindelle, Jérôme ULg et al

in Archives of Animal Nutrition (in press)

Although fermentable carbohydrates (CHO) can reduce metabolites derived from dietary protein fermentation in the intestine of pigs, the interaction between site of fermentation and substrate availability ... [more ▼]

Although fermentable carbohydrates (CHO) can reduce metabolites derived from dietary protein fermentation in the intestine of pigs, the interaction between site of fermentation and substrate availability along the gut is still unclear. The current study aimed at determining the impact of two different sources of carbohydrates in diets with low or very high protein content on microbial metabolite profiles along the gastrointestinal tract of piglets. Thirty-six piglets (n = 6 per group) were fed diets high (26%, HP) or low (18%, LP) in dietary protein and with or without two different sources of carbohydrates (12% sugar beet pulp, SBP, or 8% lignocellulose, LNC) in a 2 × 3 factorial design. After 3 weeks, contents from stomach, jejunum, ileum, caecum, proximal and distal colon were taken and analysed for major bacterial metabolites (D-lactate, L-lactate, short chain fatty acids, ammonia, amines, phenols and indols). Results indicate considerable fermentation of CHO and protein already in the stomach. HP diets increased the formation of ammonia, amines, phenolic and indolic compounds throughout the different parts of the intestine with most pronounced effects in the distal colon. Dietary SBP inclusion in LP diets favoured the formation of cadaverine in the proximal parts of the intestine. SBP mainly increased CHO-derived metabolites such as SCFA and lactate and decreased protein-derived metabolites in the large intestine. Based on metabolite profiles, LNC was partly fermented in the distal large intestine and reduced mainly phenols, indols and cadaverine, but not ammonia. Multivariate analysis confirmed more diet-specific metabolite patterns in the stomach, whereas the CHO addition was the main determinant in the caecum and proximal colon. The protein level mainly influenced the metabolite patterns in the distal colon. The results confirm the importance of CHO source to influence the formation of metabolites derived from protein fermentation along the intestinal tract of the pig. [less ▲]

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See detailAmulettes coptes « jumelles » de Strasbourg : P.Strasb. K 201 et K 202
de Haro Sanchez, Magali ULg

in Boud'hors; Delattre; Louis, Catherine (Eds.) et al Études coptes XII (in press)

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See detailL'idéologie de la Nieuw‐Vlaamse Alliantie
Jamin, Jérôme ULg

in Revue européenne de géopolitique Outre-Terre (in press)

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See detailMathématiques convoquées par le registre graphique au sein du cours de physique
Renkens, Céline; Henry, Valérie ULg

in Actes de la CIEAEM 66 (in press)

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See detailMurs, Frontières et Liberté(s) de Circulation
Gemenne, François ULg

Book published by Fayard (in press)

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See detailInfluence of COMT Genotype on Antero-Posterior Cortical Functional Connectivity Underlying Interference Resolution
Jaspar, Mathieu ULg; Manard, Marine ULg; DIDEBERG, Vinciane ULg et al

in Cerebral Cortex (in press)

Genetic variability related to the catechol-O-methyltransferase (COMT) gene (Val158Met) has received increasing attention as a possible modulator of executive functioning and its neural correlates ... [more ▼]

Genetic variability related to the catechol-O-methyltransferase (COMT) gene (Val158Met) has received increasing attention as a possible modulator of executive functioning and its neural correlates. However, this attention has generally centred on the prefrontal cortices because of the well-known direct impact of COMT enzyme on these cerebral regions. In this study, we were interested in the modulating effect of COMT genotype on anterior and posterior brain areas underlying interference resolution during a Stroop task. More specifically, we were interested in the functional connectivity between the right inferior frontal operculum (IFop), an area frequently associated with inhibitory efficiency, and posterior brain regions involved in reading/naming processes (the two main non-executive determinants of the Stroop effect). The Stroop task was administered during fMRI scanning to three groups of 15 young adults divided according to their COMT Val158Met genotype [Val/Val (VV), Val/Met (VM) and Met/Met (MM)]. Results indicate greater activity in the right IFop and the left middle temporal gyrus (MTG) in homozygous VV individuals than in Met allele carriers. In addition, the VV group exhibited stronger positive functional connectivity between these two brain regions and stronger negative connectivity between the right IFop and left lingual gyrus. These results confirm the impact of COMT genotype on frontal function. They also strongly suggest that differences in frontal activity influence posterior brain regions related to a non-executive component of the task. Especially, changes in functional connectivity between anterior and posterior brain areas might correspond to compensatory processes for performing the task efficiently when the available dopamine level is low. [less ▲]

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See detailOsteoporosis in patients taking selective serotonin reuptake inhibitors: a focus on fracture outcome
Bruyère, Olivier ULg; Reginster, Jean-Yves ULg

in Endocrine (in press)

Depression is one of the most important mental health problems and a leading cause of disability. Selective serotonin reuptake inhibitors (SSRIs) are considered as first-line therapy for the treatment of ... [more ▼]

Depression is one of the most important mental health problems and a leading cause of disability. Selective serotonin reuptake inhibitors (SSRIs) are considered as first-line therapy for the treatment of depressive symptoms among older adults because of their presumed favorable adverse effect profile. However, they could have deleterious effects on the bone. Evidence from longitudinal, crosssectional, and prospective cohort studies suggests that the use of antidepressants at therapeutic doses is associated with decreased bone mineral density and increased fracture risk. The association between SSRIs use and fracture risk could potentially differ depending on dose, exposure duration, time of exposure, age, or sex. However, the risk of fracture declined rapidly after discontinuation of use of SSRIs. The evidence now seems sufficient to consider adding SSRIs to the list of medications that contribute to osteoporosis. In practice, assessment of risk factor for osteoporosis or fractures could be made taking into account age, gender, duration, and severity of depression, length of SSRI treatments, and other concurrent risk factors. [less ▲]

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See detailA l'ombre de Sainte-Waudru. L'architecture religieuse dans la prévôté de Mons aux XVe et XVIe siècles
Joly, Emmanuel ULg

Article for general public (in press)

La pose de la première pierre de la nouvelle collégiale Sainte-Waudru le 9 mars 1450 marque le début d’un chantier qui s’étalera sur plus de deux siècles. Pendant ce temps, la ville de Mons ainsi que la ... [more ▼]

La pose de la première pierre de la nouvelle collégiale Sainte-Waudru le 9 mars 1450 marque le début d’un chantier qui s’étalera sur plus de deux siècles. Pendant ce temps, la ville de Mons ainsi que la circonscription administrative dont elle est le centre se dotent de nombreux autres édifices religieux. Ces modestes collégiales ou églises paroissiales (voire succursales) grandissent à l’ombre de Sainte-Waudru et présentent des partis constructifs souvent très différents de ceux mis en œuvre à la grande collégiale montoise. Pourtant, à l’inverse de la collégiale Sainte-Waudru , ces architectures ont rarement fait l’objet de publications scientifiques et restent dès lors fort méconnues. [less ▲]

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See detailL'église Saint-Julien d'Ath avant 1817 : essai de reconstitution d'un édifice disparu
Joly, Emmanuel ULg

Article for general public (in press)

L’état de l’église Saint-Julien avant l’incendie de 1817 est fort méconnu, bien que les parties gothiques de l’édifice fassent régulièrement l’objet de descriptions, de notices, de mentions voire ... [more ▼]

L’état de l’église Saint-Julien avant l’incendie de 1817 est fort méconnu, bien que les parties gothiques de l’édifice fassent régulièrement l’objet de descriptions, de notices, de mentions voire d’analyses dans les synthèses consacrées à l’architecture médiévale en Belgique ou en Hainaut. Or pour pouvoir procéder à des comparaisons et replacer l’église dans l’architecture de son époque, il est important d’en avoir une image fidèle. Il faut donc nous pencher sur les divers types de sources (iconographiques, textuelles et archéologiques) à notre disposition pour reconstituer l’église dans son aspect antérieur à 1817. [less ▲]

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See detailA mysterious giant ichthyosaur from the lowermost Jurassic of Wales
Martin, Jeremy E; Vincent, Peggy; Suan, Guillaume et al

in Acta Palaeontologica Polonica (in press)

Ichthyosaurs rapidly diversified and colonised a wide range of ecological niches during the Early and Middle Triassic period, but experienced a major decline in diversity near the end of the Triassic ... [more ▼]

Ichthyosaurs rapidly diversified and colonised a wide range of ecological niches during the Early and Middle Triassic period, but experienced a major decline in diversity near the end of the Triassic. Timing and causes of this demise and the subsequent rapid radiation of the diverse, but less disparate, parvipelvian ichthyosaurs are still unknown, notably because of inadequate sampling in strata of latest Triassic age. Here, we describe an exceptionally large radius from Lower Jurassic deposits at Penarth near Cardiff, South Wales (UK) the morphology of which places it within the giant Triassic shastasaurids. A tentative total body size estimate, based on a regression analysis of various complete ichthyosaur skeletons, yields a value of 12-15 m. The specimen is substantially younger than any previously reported last known occurrences of shastasaurids and implies a Lazarus range in the lowermost Jurassic for this ichthyosaur morphotype. [less ▲]

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See detailFatal transmission of contagious caprine pleuropneumonia to an Arabian oryx (Oryx leucoryx)
Chaber, AL; Lignereux, L; Al Qassimi, M et al

in Veterinary Microbiology (in press)

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See detailBayesian versus frequentist methods for estimating disease true prevalence and 4 diagnostic test performance
Sanogo, M; Abatih, E; Saegerman, Claude ULg

in Veterinary Journal (in press)

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See detailMonitoring of osteoporosis therapy
Bruyère, Olivier ULg; Reginster, Jean-Yves ULg

in Best Practice & Research. Clinical Endocrinology & Metabolism (in press)

Over the past two decades, major advances have been made in the number and range of agents available for the treatment of osteoporosis, all with proven anti-fracture efficacy. Unfortunately, compliance ... [more ▼]

Over the past two decades, major advances have been made in the number and range of agents available for the treatment of osteoporosis, all with proven anti-fracture efficacy. Unfortunately, compliance with these treatments is not optimal, and a number of patients could be considered as non-responders. Consequently, monitoring anti-osteoporotic therapy could be part of successful osteoporosis management. Currently, no formal well-accepted clinical practice guidelines are available for monitoring anti-osteoporosis therapies. Changes in bone mineral density and bone turnover markers, while on therapy, have potential value in monitoring treatment but their assessment and, consequently, their benefits could be limited by metrological and clinical issues. Moreover, their effectiveness is probably drug dependant. Recommendation for the standardisation of the methodology when analysing the potential relevance of tools for the monitoring of osteoporosis therapy is needed. [less ▲]

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See detailChronique bibliographique - Supplément 2005-2008
Veymiers, Richard ULg; Bricault, Laurent; Malaise, Michel et al

in Bricault, Laurent; Veymiers, Richard (Eds.) Bibliotheca Isiaca III (in press)

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See detailCarbon and Other Biogeochemical Cycles
Ciais, Philippe; Sabine, Christopher; Bala, Govindasamy et al

in Stocker, T. F.; Qin, D.; Plattner, G.-K. (Eds.) et al Climate Change 2013: The Physical Science Basis. Contribution of Working Group I to the Fifth Assessment Report of the Intergovernmental Panel on Climate Change (in press)

The present perturbations of the biogeochemical cycles of carbon dioxide (CO2), methane (CH4) and nitrous oxide (N2O), as well as their past variations (coupled to climate variations) and their projected ... [more ▼]

The present perturbations of the biogeochemical cycles of carbon dioxide (CO2), methane (CH4) and nitrous oxide (N2O), as well as their past variations (coupled to climate variations) and their projected future evolutions over the 21st century are reviewed. [less ▲]

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See detailChemical abundances of fast-rotating OB stars
Cazorla, Constantin ULg; Morel, Thierry ULg; Nazé, Yaël ULg et al

in IAU Symposium (in press)

Fast rotation in massive stars is predicted to induce mixing in their interior, but a population of fast-rotating stars with normal nitrogen abundances at their surface has recently been revealed (Hunter ... [more ▼]

Fast rotation in massive stars is predicted to induce mixing in their interior, but a population of fast-rotating stars with normal nitrogen abundances at their surface has recently been revealed (Hunter et al. 2009; Brott et al. 2011, but see Maeder et al. 2014). However, as the binary fraction of these stars is unknown, no definitive statements about the ability of single-star evolutionary models including rotation to reproduce these observations can be made. Our work combines for the first time a detailed surface abundance analysis with a radial-velocity monitoring for a sample of bright, fast-rotating Galactic OB stars to put strong constraints on stellar evolutionary and interior models. [less ▲]

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