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See detailAktueller Stand der Projekte QuaM, ManageMilk und OptiMir (Erste Ergebnisse sind vielversprechend)
Reding, Romain; Arnould, Valérie ULg

Article for general public (2013)

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See detailDevelopment of a quantitative immunocapture real-time PCR assay for detecting structurally intact adenoviral particles in water
Ogorzaly, Leslie; Bonot, Sébastien; Elmoualij, Benaïssa ULg et al

in Journal of Virological Methods (2013), 194

Development of rapid, sensitive and specific methods for detection of infectious enteric viruses in water is challenging but crucial for gaining reliable information for risk assessment. An immunocapture ... [more ▼]

Development of rapid, sensitive and specific methods for detection of infectious enteric viruses in water is challenging but crucial for gaining reliable information for risk assessment. An immunocapture real-time PCR (IC-qPCR) was designed to detect jointly the two major viral particle components, i.e. the capsid protein and the viral genome. Targeting both constituents helps circumventing the technical limits of cell culture approaches and the inability of PCR based methods to predict the infectious status. Two waterborne pathogenic virus models, human adenovirus types 2 and 41, were chosen for this study. IC-qPCR showed a detection limit of 10 MPNCU/reaction with a dynamic range from 102 to 106 MPNCU/reaction. Sensitivity was thus 100-fold higher compared to ELISA-based capture employing the same anti-hexon antibodies. After optimisation, application on environmental water samples was validated, and specificity towards the targeted virus types was obtained through the qPCR step. Heat-treated pure samples as well as surface water samples brought evidence that this method achieves detection of encapsidated viral genomes while excluding free viral genome amplification. As a consequence, adenovirus concentrations estimated by IC-qPCR were below those calculated by direct qPCR. The results demonstrate that the IC-qPCR method is a sensitive and rapid tool for detecting, in a single-tube assay, structurally intact and thus potentially infectious viral particles in environmental samples. [less ▲]

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See detailA New Validated Method for Improving the Audiovisual Spatial Congruence in the Case of Stereoscopic-3D Video and Wave Field Synthesis
André, Cédric ULg; Corteel, Etienne; Embrechts, Jean-Jacques ULg et al

in 3D Imaging (IC3D), 2013 International Conference on (2013, December)

While 3D cinema is becoming increasingly established, little effort has focused on the general problem of producing a 3D sound scene spatially coherent with the visual content of a stereoscopic-3D (s-3D ... [more ▼]

While 3D cinema is becoming increasingly established, little effort has focused on the general problem of producing a 3D sound scene spatially coherent with the visual content of a stereoscopic-3D (s-3D) movie. The perceptual relevance of such spatial audiovisual coherence is of significant interest. In this paper, we explain why the combination of accurate sound positioning and stereoscopic-3D images can lead to an incongruence between the sound and the image for multiple spectators. Then, we adapt to s-3D viewing a method originally proposed for 2D images in the literature to reduce this error. Finally, a subjective experiment is carried out to prove the efficiency of the method. [less ▲]

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See detailOn the statistical assessment of small sample classification
Noirhomme, Quentin ULg; Lesenfants, Damien ULg; Gomez, Francisco et al

Conference (2013, December)

Classifiers start to be used in medical application to infer diagnosis. Their results are assessed through either a binomial or a permutation test. Distributions built from classification of random data ... [more ▼]

Classifiers start to be used in medical application to infer diagnosis. Their results are assessed through either a binomial or a permutation test. Distributions built from classification of random data with cross-validation, did not follow the theoretical binomial distribution, showing that binomial test was not conservative enough. A permutation test is thus recommended. [less ▲]

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See detailLes orthophonistes utilisent-ils les données issues de la recherche scientifique ? Analyse des pratiques afin d’ajuster la formation universitaire en Belgique
Durieux, Nancy ULg; Pasleau, Françoise ULg; Vandenput, Sandrina ULg et al

in Glossa (2013, December), 113

Une des missions fondamentales d’une formation universitaire est de permettre aux futurs professionnels d’identifier et de traiter efficacement les informations nécessaires aux prises de décisions parmi ... [more ▼]

Une des missions fondamentales d’une formation universitaire est de permettre aux futurs professionnels d’identifier et de traiter efficacement les informations nécessaires aux prises de décisions parmi un nombre toujours croissant de documents disponibles. Pour atteindre cet objectif, le recours à l’Evidence-Based Practice (EBP) s’avère une approche méthodologique permettant d’acquérir les savoirs et savoir-faire requis pour, notamment, la recherche d’informations probantes. L’EBP doit donc logiquement faire partie de la formation initiale des futurs orthophonistes en restant en adéquation avec les besoins et pratiques des professionnels. À cette fin, il est important d’identifier les questions que se posent les cliniciens dans leur pratique quotidienne, la manière dont ils trouvent des réponses et s’ils ont recours ou non aux données issues de la recherche scientifique. Une enquête a été lancée en mai 2012 auprès d’orthophonistes travaillant en Communauté française de Belgique. La présente communication exposera les principaux résultats, recueillis auprès de 410 orthophonistes, qui conduiront à des pistes d’action pour l’enseignement universitaire et la formation continue. [less ▲]

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See detailMise en route d'un robot mobile: réponses aux contraintes techniques
Lessire, Françoise ULg; Knapp, Emilie ULg; Dufrasne, Isabelle ULg

in Point Vétérinaire (2013), 341

This paper explains the technical problems related to the use of a mobile automatic miking system and the solutions found at the University of Liege.

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See detailTraite robotisée et pâturage sont-ils compatibles?
Lessire, Françoise ULg; Knapp, Emilie ULg; Dufrasne, Isabelle ULg

in Point Vétérinaire (2013), 341

Combining automatic milking system and grazing is often considered as impossible. This paper defined the difficulties related to grazing cows milked by a robot and how to manage them.

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See detailOn periodic reference tracking using batch-mode reinforcement learning with application to gene regulatory network control
Sootla, Aivar; Strelkowa, Natajala; Ernst, Damien ULg et al

in Proceedings of the 52nd Annual Conference on Decision and Control (CDC 2013) (2013, December)

In this paper, we consider the periodic reference tracking problem in the framework of batch-mode reinforcement learning, which studies methods for solving optimal control problems from the sole knowledge ... [more ▼]

In this paper, we consider the periodic reference tracking problem in the framework of batch-mode reinforcement learning, which studies methods for solving optimal control problems from the sole knowledge of a set of trajectories. In particular, we extend an existing batch-mode reinforcement learning algorithm, known as Fitted Q Iteration, to the periodic reference tracking problem. The presented periodic reference tracking algorithm explicitly exploits a priori knowledge of the future values of the reference trajectory and its periodicity. We discuss the properties of our approach and illustrate it on the problem of reference tracking for a synthetic biology gene regulatory network known as the generalised repressilator. This system can produce decaying but long-lived oscillations, which makes it an interesting application for the tracking problem. [less ▲]

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See detailINFLUENCE OF SOLUBLE PROTEINS ON THE ADHERENCE OF PARTICULATE SOILS
Toure, Yetioman ULg; Rouxhet, Paul; Dupont-Gillain, Christine et al

in Malayeri, Reza; Watkinson, Paul A.; Müller-Steinhagen, Hans (Eds.) Proceedings of International Conference on Heat Exchanger Fouling and Cleaning - 2013 (Peer-reviewed) (2013, December)

Adsorbed compounds from food and pharmaceutical mixtures may influence interactions at interfaces and thus fouling and cleaning. In this study, quartz particles (10 to 30µm) were used as a model soil for ... [more ▼]

Adsorbed compounds from food and pharmaceutical mixtures may influence interactions at interfaces and thus fouling and cleaning. In this study, quartz particles (10 to 30µm) were used as a model soil for examining the effect of dissolved proteins on the cleanability of substrates after soiling and drying. Glass and stainless steel pretreated by UV-Ozone (StSteel-UVO) were used as model hydrophilic substrates, while hydrophobic substrates were represented by stainless steel cleaned with ethanol (StSteel-Eth) and polystyrene. BSA and β-LGB were used as proteins. The quartz suspensions used for soiling were prepared in pure water and in a solution of each protein. After soiling and drying, the cleanability was evaluated using a radial-flow cell, with pure water as the cleaning fluid. The presence of proteins in the suspension used for soiling hydrophilic substrates (Glass and StSteel-UVO), decreased the adherence of quartz particles. Its effect was less marked and tended to be opposite for less hydrophilic substrates (StSteel-Eth, Polystyrene). The adherence cannot be explained by a simple relation with the contact angle. Other factors may be the solution surface tension itself and the protein behavior at the interfaces created by drying and by rehydratation during cleaning. When considering the influence of substrate on soiling, it must be kept in mind that high surface energy solids (metals, oxides) are readily contaminated in contact with air and lose their hydrophilicity. This may improve the substrate behavior regarding cleanability with respect to particulate soil. [less ▲]

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See detailGrasshoppers: Food Security & Nutrition
Paul, Aman ULg; Danthine, Sabine ULg; Frederich, Michel ULg et al

Scientific conference (2013, December)

Rising economies and rapid urbanization in developing countries, particularly in Asia, are creating shifts in the composition of global food demand, so it is necessary to explore new sources of food with ... [more ▼]

Rising economies and rapid urbanization in developing countries, particularly in Asia, are creating shifts in the composition of global food demand, so it is necessary to explore new sources of food with better nutritional profile. Among the alternative food that exists are the grasshoppers, about 80 species of which are consumed worldwide. Grasshoppers are not only rich source of proteins and lipids but also some important minor component like vitamins and minerals. Apart from being nutritionally superior to most conventional meats their production results in lower emission of greenhouse gases & ammonia, risk of zoonotic infections in humans is much lower, water requirement for production is much less and have higher feed conversion ratio. Edible species of grasshopper in Belgium were identified, attempts were made for the lab rearing of meadow grasshopper (Chorthippus parallelus) and fat as well as protein contents of meadow grasshopper (Chorthippus parallelus) & long winged conehead (Conocephalus discolor) were investigated. [less ▲]

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See detailGérer la diversité au quotidien Cas pratiques de GRH
Cornet, Annie ULg; Warland, Philippe ULg

Book published by ATELIER DES PRESSES (2013)

CAS PRATIQUES POUR FORMATEURS ET ETUDIANTS

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See detailA giant treated with growth hormone
Rostomyan, Liliya ULg; Potorac, Iulia ULg; CASTERMANS, Emilie ULg et al

in The 3rd ENEA Workshop : Hypopituitarism - Abstract book (2013, December)

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See detailLa cascade des MAP kinases : traitements ciblés en cancérologie cutanée.
PIERARD, Gérald ULg; Franchimont, Claudine ULg; LEONARD, Boris ULg et al

in Revue Médicale de Liège (2013), 68(12), 650-654

Résumé : Les «Mitogen-Activated Protein Kinases» (MAPK) forment un ensemble coordonné de protéines cellulaires impliquées dans la prolifération, la différenciation, la migration et l’apoptose des cellules ... [more ▼]

Résumé : Les «Mitogen-Activated Protein Kinases» (MAPK) forment un ensemble coordonné de protéines cellulaires impliquées dans la prolifération, la différenciation, la migration et l’apoptose des cellules. Elles sont particulièrement activées, par certaines cytokines, hormones, le stress environnemental, ainsi que dans des cancers cutanés. Des agents pharmacologiques ciblés contre la cascade MAPK révolutionnent actuellement la cancérologie cutanée, du moins dans une phase transitoire du processus métastatique. Des traitements combinés sont susceptibles d’améliorer la survie médiane. [less ▲]

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See detailHypopituitarism in pituitary gigantism (results of an international study)
Rostomyan, Liliya ULg; Daly, Adrian ULg; Shah, NS et al

in The 3rd ENEA Workshop : Hypopituitarism - Abstract book (2013, December)

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See detailPhysicochemical properties of lipids extracted from Tenebrio molitor larvae
Danthine, Sabine ULg; Blecker, Christophe ULg; Paul, Aman ULg et al

Poster (2013, December)

Objectives: To determine the physicochemical properties of the oil obtained from Tenebrio molitor Larvae and explore its potential as edible oil. Methodology: Oils obtained from five batches of Tenebrio ... [more ▼]

Objectives: To determine the physicochemical properties of the oil obtained from Tenebrio molitor Larvae and explore its potential as edible oil. Methodology: Oils obtained from five batches of Tenebrio molitor Larvae were investigated. Among the samples, three were produced directly in the lab (3 different productions) and 2 were purchased from a local supplier. In addition to the total lipid content (solvent extraction), both FA (GC) and TAG (HPLC) profiles were determined. Thermal properties by DSC were also estimated. Results and conclusion: The fresh Larvae from the lab contained 52% of total proteins (% dry matter). Their total fat content was around 36% (% dry matter). The commercial samples contained more proteins, but less fat: around 58% of total proteins and 30% of total fat (% dry matter). All the extracted oils contained high amount of unsaturated fatty acids. However, the chemical composition and the thermal properties of the samples varied according to their origin. The level and quality of lipid content offer potential as a substitute of oilseeds. [less ▲]

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See detailA spectral operator-theoretic framework for global stability
Mauroy, Alexandre ULg; Mezic, Igor

in Proceedings of the IEEE Conference on Decision and Control (2013, December)

The global description of a nonlinear system through the linear Koopman operator leads to an efficient approach to global stability analysis. In the context of stability analysis, not much attention has ... [more ▼]

The global description of a nonlinear system through the linear Koopman operator leads to an efficient approach to global stability analysis. In the context of stability analysis, not much attention has been paid to the use of spectral properties of the operator. This paper provides new results on the relationship between the global stability properties of the system and the spectral properties of the Koopman operator. In particular, the results show that specific eigenfunctions capture the system stability and can be used to recover known notions of classical stability theory (e.g. Lyapunov functions, contracting metrics). Finally, a numerical method is proposed for the global stability analysis of a fixed point and is illustrated with several examples. [less ▲]

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See detailBioRefine: Recovery of Nutrients from Sewage Sludge, Manure and Digestate by a Combination of Chemical and Biochemical Unit Operations
Tarayre, Cédric ULg; Delvigne, Frank ULg; Michels, Evi et al

Poster (2013, December)

At this time, many wastes are exploited through processes that do not really consider applications potentially more profitable. Such wastes contain reusable components, such as nitrogen, phosphorus and ... [more ▼]

At this time, many wastes are exploited through processes that do not really consider applications potentially more profitable. Such wastes contain reusable components, such as nitrogen, phosphorus and potassium, whereas heavy metals may also be considered. Their composition depends on input materials, and considerable heterogeneities must be highlighted. Sewage sludge is usually exploited as a fertilizer in agriculture, in energy production or in the field of construction. The main application of manure is agriculture, although considerable amounts of nutrients are lost and cause pollution. Digestate is also used in agriculture, but other alternatives have been proposed, such as combustion. The use of waste in agriculture must respect many legal constraints. Another problematic point is the concentration of heavy metals that is found in those wastes. Consequently, recovery of nutrients and trace elements may be a key solution. Chemical and biochemical engineering propose many unit operations (mechanical operations on fluids, solids, mass and heat transfers, chemical reactions, etc.) that may be used to reach an efficient recovery yield of capital nutrients and trace elements. Here, we propose a methodology which consists in considering the unit operations separately with their own input and output flows, energy and heat consumption, investment, etc. and combining them to simulate industrial processes. The element concentrations and their forms will also be considered using a classification matrix. Combinations of unit operations will lead to reliable processes that should be applied on an industrial scale. This work is supported by the BioRefine Project, a European project in which various member states focus on recovery of inorganics from organic waste streams. We gratefully acknowledge the INTERREG IVB NWE programme, which financed the BioRefine Project (ref. 320J-BIOREFINE). [less ▲]

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See detailPotentiel d'utilisation de la spectrometrie moyen infrarouge pour prédire le rendement fromager du lait et étudier sa variabilité génétique
Colinet, Frédéric ULg; Troch, Thibault ULg; Abbas, O. et al

in 20èmes Rencontres Recherches Ruminants, Paris, les 4 et 5 Décembre 2013 (2013, December)

Fournir une indication rapide, fiable et bon marché du rendement fromager pour un lait donné, sans devoir appliquer des formules (empiriques ou théoriques) à partir des concentrations préalablement ... [more ▼]

Fournir une indication rapide, fiable et bon marché du rendement fromager pour un lait donné, sans devoir appliquer des formules (empiriques ou théoriques) à partir des concentrations préalablement déterminées pour différents constituants du lait, serait un outil utile et économiquement intéressant tant pour les éleveurs que pour l’industrie laitière. En vue d’étudier la variabilité génétique du rendement fromager à l’échelle du cheptel bovin wallon, des méthodes chimiométriques ont été utilisées afin de développer des équations de prédictions basées sur des spectres moyen infrarouge (MIR) pour les rendements fromagers déterminés en laboratoire et exprimés en frais (RdFF) ou en sec (RdFS). Ceux-ci ont été déterminés sur 258 échantillons de lait analysés en spectrométrie MIR. Les équations de prédiction à partir du spectre MIR du lait ont été développées en utilisant la régression des moindres carrés partiels (PLS) avec une validation croisée interne appliquée sur la dérivée première des spectres MIR. Les coefficients de détermination de validation croisée (R²cv) des équations étaient de 0,81 pour les prédictions du RdFF et de 0,82 pour les celles du RdFS. Les rapports des performances sur les variabilités (RPD) étaient égaux à 2,3. Ces résultats peuvent permettre d’envisager une bonne utilité pratique pour leur prédiction respective, notamment dans le cadre de recherches génétiques. Ces équations ont été appliquées sur la base de données spectrales générée dans le cadre du contrôle laitier wallon. Les composantes de la variance ont été estimées séparément pour le RdFF et le RdFS basées sur un modèle animal « contrôles élémentaires » utilisant des régressions aléatoires. Le jeu de données utilisé comportait 51 537 prédictions pour 7 870 vaches primipares Holstein. Les héritabilités journalières moyennes variaient entre 0,31 (au 5ème jour de lactation (JDL)) et 0,59 (au 279ème JDL) pour le RdFF et entre 0,31 (au 5ème JDL) et 0,57 (au 299ème JDL) pour le RdFS. Ces héritabilités journalières modérées à élevées ont indiqué le potentiel de sélection génétique pour ces deux caractères. [less ▲]

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See detailResponding Bodies and Partial Affinities in Human–Animal Worlds
Despret, Vinciane ULg

in Theory, Culture & Society (2013), 30(7/8), 66-91

The aim of this paper is to explore the different manners in which scientists’ bodies are actively engaged when interacting with the animals they observe in the field. Bodies are multiple, as are the ... [more ▼]

The aim of this paper is to explore the different manners in which scientists’ bodies are actively engaged when interacting with the animals they observe in the field. Bodies are multiple, as are the practices that involve them: sharing the same diet, feeling similar affects, acting the same, inhabiting the same world of perceptions, constructing empathic affinities, etc.
Some scientists aim to embody the animals’ experiences. Some are willing to empathetically experience situations “from inside”, while others “undo and redo” their own bodies in order to interact more closely with the animals and to respond to them more cautiously. Still others are faced with the question: what can we do or what are we allowed to do with our bodies when we are with our animals?
All of these practices present a very different version of “embodied empathy”, a concept which describes feeling/seeing/thinking bodies that undo and redo each other, reciprocally though not symmetrically, as partial perspectives that attune themselves to each other. Therefore, empathy is not experiencing with one’s own body what the other experiences, but rather creating the possibilities of an embodied communication. [less ▲]

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