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See detailRésultats des enquêtes "Attrait des Sciences" (années académiques 2015–2016 et 2016–2017)
Aerts, Stéphanie ULiege; Ernst, Marie ULiege

Report (2017)

Lors des rentrées académiques 2015-2016 et 2016-2017, une enquête a été envoyée aux étudiants primants inscrits en Faculté des Sciences. Cette enquête interroge les étudiants sur leur parcours secondaire ... [more ▼]

Lors des rentrées académiques 2015-2016 et 2016-2017, une enquête a été envoyée aux étudiants primants inscrits en Faculté des Sciences. Cette enquête interroge les étudiants sur leur parcours secondaire, leur choix d'étude, leur avenir professionnel et leurs aptitudes. Ce rapport consiste en une analyse descriptive et exploratoire des résultats des deux enquêtes. [less ▲]

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See detailUnexpected diversification of pliosaurid marine reptiles after the Jurassic-Cretaceous boundary
Fischer, Valentin ULiege; Benson, Roger; Zverkov, Nikolay et al

Conference (2017, April)

Pliosaurids are iconic marine reptiles that dominated marine ecosystems during the Jurassic and the Cretaceous. These giant predators met their demise during the early Late Cretaceous but the final ... [more ▼]

Pliosaurids are iconic marine reptiles that dominated marine ecosystems during the Jurassic and the Cretaceous. These giant predators met their demise during the early Late Cretaceous but the final chapter of their long evolutionary history remains barely documented. Prompted by the discovery of a peculiar and very well preserved new taxon from Russia, we compute the evolution of pliosaurid disparity from their Early Jurassic radiation to their Late Cretaceous extinction. Despite a patchy Early Cretaceous fossil record, we show pliosaurids reached their maximal disparity during the Hauterivian-Barremian interval, suggesting a strong Early Cretaceous recovery from the apparently low phenotypic disparity of Late Jurassic pliosaurids. By using cladistic and ecomorphological data, we show that pliosaurids have repeatedly evolved slender-snouted polycotylid-like morphologies in each of their temporal radiations (Early Jurassic, Middle Jurassic and Early Cretaceous), demonstrating a more complex evolutionary history than their traditional representation as gigantic apex predators of Mesozoic marine ecosystems suggests. The extinction of pliosaurids during the Turonian (early Late Cretaceous) appears preceded by a late Early Cretaceous contraction of their disparity, the trajectory documented in ichthyosaurs, another successful marine reptile clade that disappeared during the Cenomanian-Turonian interval. [less ▲]

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See detail"La madone et la putain": Quand les stéréotypes de genres influencent la perception de la légalité des violences sexuelles et le traitement de la réaction sociale à l'égard des femmes
Garcet, Serge ULiege

in Revue de la Faculté de Droit de l'Université de Liège (2017), 2017/1

Les illégalités liées au traitement différentiel des genres reposent notamment sur la présence de stéréotypes sexistes. L’article illustre comment les attitudes subjectivement positives à l’égard des ... [more ▼]

Les illégalités liées au traitement différentiel des genres reposent notamment sur la présence de stéréotypes sexistes. L’article illustre comment les attitudes subjectivement positives à l’égard des femmes que l’on peut qualifier de stéréotypes sexistes bienveillants influencent tant positivement que négativement la façon dont les femmes sont perçues par le système judiciaire. L’article souligne également au travers des représentations liées aux violences sexuelles l’impact des stéréotypes sexistes hostiles sur la perception de la légalité, de la légitimité perçue du passage à l’acte et du statut des victimes. [less ▲]

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See detailIdentification of Shiga toxin-producing (STEC) and enteropathogenic (EPEC) Escherichia coli in diarrhoeic calves and comparative genomics of O5 bovine and human STEC
Fakih, Ibrahim; Thiry, Damien ULiege; Duprez, Jean-Noël ULiege et al

in Veterinary Microbiology (2017), 202

Escherichia coli producing Shiga toxins (Stx) and the attaching-effacing (AE) lesion (AE-STEC) are responsible for (bloody) diarrhoea in humans and calves while the enteropathogenic E. coli (EPEC ... [more ▼]

Escherichia coli producing Shiga toxins (Stx) and the attaching-effacing (AE) lesion (AE-STEC) are responsible for (bloody) diarrhoea in humans and calves while the enteropathogenic E. coli (EPEC) producing the AE lesion only cause non-bloody diarrhoea in all mammals. The purpose of this study was (i) to identify the pathotypes of enterohaemolysin-producing E. coli isolated between 2009 and 2013 on EHLY agar from less than 2 month-old diarrhoeic calves with a triplex PCR targeting the stx1, stx2, eae virulence genes; (ii) to serotype the positive isolates with PCR targeting the genes coding for ten most frequent and pathogenic human and calf STEC O serogroups; and (iii) to compare the MLSTypes and virulotypes of calf and human O5 AE-STEC after Whole Genome Sequencing using two server databases (www.genomicepidemiology.org). Of 233 isolates, 206 were triplex PCR-positive: 119 AE-STEC (58%), 78 EPEC (38%) and 9 STEC (4%); and the stx1+eae+ AE-STEC (49.5%) were the most frequent. Of them, 120 isolates (84% of AE-STEC, 23% of EPEC, 22% of STEC) tested positive with one O serogroup PCR: 57 for O26 (47.5%), 36 for O111 (30%), 10 for O103 (8%) and 8 for O5 (7%) serogroups. The analysis of the draft sequences of 15 O5 AE-STEC could not identify any difference correlated to the host. As a conclusion, (i) the AE-STEC associated with diarrhoea in young calves still belong to the same serogroups as previously (O5, O26, O111) but the O103 serogroup may be emerging, (ii) the O5 AE-STEC from calves and humans are genetically similar [less ▲]

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See detailIntroduction to Nonlinear Aeroelasticity
Dimitriadis, Grigorios ULiege

Book published by Wiley (2017)

Nonlinear aeroelasticity has become an increasingly popular research area over the last 20-30 years. There have been many driving forces behind this development, including faster computers, increasingly ... [more ▼]

Nonlinear aeroelasticity has become an increasingly popular research area over the last 20-30 years. There have been many driving forces behind this development, including faster computers, increasingly flexible structures, automatic control systems for aircraft and other engineering products, new materials with nonlinear characteristics etc. Introduction to Nonlinear Aeroelasticity covers the theoretical basics in nonlinear aeroelasticity and applies the theory to practical problems. As nonlinear aeroelasticity is a combined topic, necessitating expertise from different areas, this book also covers areas such as nonlinear dynamics, bifurcation analysis, numerical methods and others. The emphasis throughout is on the practical application of the theories and methods, so as to enable the reader to apply their newly acquired knowledge [less ▲]

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See detailDie Zerfleischung der French Theory im Mondschein. Zu Laurent Binets "Die siebte Sprachfunktion"
Neelsen, Sarah ULiege

Article for general public (2017)

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See detailL'image du mois: Perforation intestinale grêle sur corps étranger
Maquet, Justine ULiege; BOULANGER, Yves-Gautier ULiege; MILICEVIC, Mladen ULiege

in Revue Médicale de Liège (2017), 72(4), 165-167

Les perforations intestinales grêles sont rares et ont de multiples étiologies. Nous rapportons le cas d'un patient âgé de 52 ans présentant des douleurs chroniques en fosse iliaque gauche depuis plus de ... [more ▼]

Les perforations intestinales grêles sont rares et ont de multiples étiologies. Nous rapportons le cas d'un patient âgé de 52 ans présentant des douleurs chroniques en fosse iliaque gauche depuis plus de 9 mois. L'imagerie par entéro-IRM et CT scanner a permis de mettre en évidence d'une manière rétrospective une perforation intestinale grêle couverte par un corps étranger. L'intérêt de cette observation est de montrer d'une part les signes indirects de la perforation grêle et d'autre part le caractère migrant du corps étranger. [less ▲]

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See detailPredicting Internet Path Dynamics and Performance with Machine Learning
Wassermann, Sarah ULiege; Casas, Pedro; Cuvelier, Thibaut ULiege et al

Report (2017)

In this paper, we study the problem of predicting Internet path changes and path performance using traceroute measurements and machine learning models. Path changes are frequently linked to path inflation ... [more ▼]

In this paper, we study the problem of predicting Internet path changes and path performance using traceroute measurements and machine learning models. Path changes are frequently linked to path inflation and performance degradation; therefore, predicting their occurrence is highly relevant for performance monitoring and dynamic traffic engineering. We introduce NETPerfTrace, an Internet Path Tracking system capable of forecasting path changes and path latency variations. By relying on decision trees and using empirical distribution based input features, we show that NETPerfTrace can predict (i) the remaining life time of a path before it actually changes and (ii) the number of path changes in a certain time-slot with high accuracy. Through extensive evaluation, we demonstrate that NETPerfTrace highly outperforms DTRACK, a previous system with the same prediction targets. NETPerfTrace also offers path performance forecasting capabilities. In particular, it can predict path latency metrics, providing a system which could not only predict path changes but also forecast their impact in terms of performance variations. As an additional contribution, we release NETPerfTrace as open software to the networking community. [less ▲]

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See detailSiblings and the coming out process: a comparative case study
Haxhe, Stéphanie ULiege; Cerezo, Alison; Bergfeld, Jeanette et al

in Journal of Homosexuality (2017), 64

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See detailVille de Liège, reprenez la main ! : politique architecturale de la ville de Liège
De Visscher, Lisa ULiege

in A+ : Architecture in Belgium (2017), 265

Liège is more than an imposing train station. Some major urban developments and small interventions at the level of a neighborhood redesign the city. Several important actors intervene in the process of ... [more ▼]

Liège is more than an imposing train station. Some major urban developments and small interventions at the level of a neighborhood redesign the city. Several important actors intervene in the process of mutation in Liege, which is why a thorough architectural policy of the City of Liège must make a difference. [less ▲]

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See detailMicrofossils from the late Mesoproterozoic – early Neoproterozoic Atar/El Mreïti Group, Taoudeni Basin, Mauritania, northwestern Africa
Beghin, Jérémie ULiege; Storme, Jean-Yves; Blanpied, Christian et al

in Precambrian Research (2017), 291

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See detailRetour sur le délit collectif
Kéfer, Fabienne ULiege

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2017), (16), 738-739

La nature réglementaire des infractions de non-paiement de rémunération ne les empêche pas de former un délit collectif

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See detailZonula occludens-1/NF-κB/CXCL8: a new regulatory axis for tumor angiogenesis.
Lesage, Julien; Suarez-Carmona, Meggy; Neyrinck-Leglantier, Deborah et al

in FASEB Journal (2017), 31(4), 1678-1688

Zonula occludens-1 (ZO-1) is a submembrane scaffolding protein that may display proinvasive functions when it relocates from tight junctions into the cytonuclear compartment. This article examines the ... [more ▼]

Zonula occludens-1 (ZO-1) is a submembrane scaffolding protein that may display proinvasive functions when it relocates from tight junctions into the cytonuclear compartment. This article examines the functional involvement of ZO-1 in CXCL8/IL-8 chemokine expression in lung and breast tumor cells. ZO-1 small interfering RNA and cDNA transfection experiments emphasized regulation of CXCL8/IL-8 expression via a cytonuclear pool of ZO-1. Luciferase reporter assays highlighted a 173-bp region of CXCL8/IL-8 promoter that responded to ZO-1. Moreover, by using mutated promoter constructs, we identified a NF-κB site as critical in this activation. Furthermore, NF-κB pathway signaling analysis revealed both IκBα and p65 phosphorylation in ZO-1-overexpressing cells, and subsequent p65 silencing validated its requirement for CXCL8/IL-8 induction. Investigation of the functional implication of this regulatory axis next showed the proangiogenic activity of ZO-1 in both ex vivo and in vivo angiogenesis assays. Finally, we found that non-small-cell lung carcinoma that presented a cytonuclear ZO-1 pattern was significantly more angiogenic that that without detectable cytonuclear ZO-1 expression. Taken together, our results demonstrate that ZO-1 regulates CXCL8/IL-8 expression via the NF-κB signaling pathway and its p65 subunit, which subsequently modulates the transcription of IL-8. We also provide evidence of a newly identified regulatory pathway that could promote angiogenesis. Thus, our results support the concept that the ZO-1 shuttle from the cell junction to the cytonuclear compartment may affect both the intrinsic invasive properties of tumor cells and the establishment of the protumoral microenvironment. [less ▲]

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See detailEtude comparative des profils de dissolution in vitro de quinine sulfate générique et princeps en utilisant la Chromatographie Liquide Haute Performance
Mbinze Kindenge, Jérémie ULiege; Diallo, Tediane; Yemoa, Loconon ULiege et al

in Médecine d'Afrique Noire (2017), 64

Introduction : La quinine est une molécule préconisée pour le traitement du paludisme dans les régions où les souches de P. falciparum sont polyrésistantes. Face à l’importante utilisation de ses ... [more ▼]

Introduction : La quinine est une molécule préconisée pour le traitement du paludisme dans les régions où les souches de P. falciparum sont polyrésistantes. Face à l’importante utilisation de ses médicaments génériques d’une part, et au fléau des médicaments de qualité inférieure d’autre part, il devient plus que nécessaire d’appuyer les données des tests physico-chimiques par celles de dissolution in vitro dont l’évaluation et la comparaison des cinétiques permettra de prédire le comportement in vivo du principe actif et par conséquent l’efficacité du médicament générique. L’objectif de la présente étude est de réaliser une étude comparative de la cinétique de dissolution d’un princeps et d’un générique à base de quinine comprimé 300 mg commercialisés à Kinshasa. Matériels et méthodes : L’étude a été réalisée en utilisant trois milieux de pH différents (1,2 - 4,5 - 6,8) tels que recommandés par l’Agence Européenne de Médicament et en se servant d’un appareil de dissolution, tandis que l’équipement de chromatographie liquide à haute performance couplée à un détecteur à barrette de diodes a été utilisé pour la quantification. La méthode statistique fit factor a été appliquée pour comparer les résultats de dosage de la quinine dans les trois milieux tout en ayant évalué le biais à différents temps de dissolution. Résultats : Les différents échantillons de médicaments générique et princeps ont été conformes quant à l’identification et au dosage de la quinine, par contre leurs cinétiques de dissolution étaient non similaires. Discussion : Ceci pourrait avoir une influence sur l’efficacité du produit générique et la sécurité des consommateurs, dénotant l’importance d’examiner les profils de dissolution des génériques avant toute autorisation de mise sur le marché plus particulièrement dans les pays en voie de développement. [less ▲]

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See detailDiscovery of a woman portrait behind La Violoniste by Kees Van Dongen through hyperspectral imaging
Herens, Elodie ULiege; Defeyt, Catherine ULiege; Walter, Philippe et al

in Heritage Science (2017), 5(14),

Despite the fact that Kees Van Dongen was one of the most famous painter of the 20th century, only little information about his palette and his technique is available. To contribute to the ... [more ▼]

Despite the fact that Kees Van Dongen was one of the most famous painter of the 20th century, only little information about his palette and his technique is available. To contribute to the characterization of Van Dongen's painting materials, La Violoniste, painted by the artist around 1923, has been analyzed by using three complementary techniques: macro X-ray fluorescence (MA-XRF), Raman spectroscopy and hyperspectral imaging. The elemental repartition given by MA-XRF and the results obtained thanks to Raman spectroscopy help us to complete the identification of pigments contained in La Violoniste (lead white, iron oxides, cadmium yellow, vermilion, Prussian blue, titanium white, ultramarine, a chromium pigment and carbon black) while the results obtained via hyperspectral imaging reveal a hidden woman portrait. Besides the fact that Kees Van Dongen was particularly renowned for his female portraits, this hidden composition presents obvious stylistic similarities with the well-known portraits produced by the artist during his Parisian stay (starting from 1899). Thanks to Raman spectroscopy, visual examination and MA-XRF, we show that the original background contains ultramarine, the hidden portrait's clothes are probably made of the same colour as the present violinist's dress and her carnation contains zinc, contrary to the violinist's flesh which is mainly made of lead white. [less ▲]

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See detailIgG4-related membranous glomerulonephritis and generalized lymphadenopathy without pancreatitis: a case report
HUART, Justine ULiege; GROSCH, Stéphanie ULiege; BOVY, Christophe ULiege et al

in BMC Nephrology (2017), 18

Abstract Background: IgG4-related disease is a recently described pathologic entity. This is the case of a patient with nephrotic syndrome and lymphadenopathy due to IgG4-related disease. Such a kidney ... [more ▼]

Abstract Background: IgG4-related disease is a recently described pathologic entity. This is the case of a patient with nephrotic syndrome and lymphadenopathy due to IgG4-related disease. Such a kidney involvement is quite peculiar and has only been described a few times recently. Renal biopsy showed a glomerular involvement with membranous glomerulonephritis in association with a tubulo-interstitial nephropathy. Moreover, the patient was not suffering from pancreatitis. Case presentation: The patient is a middle-aged man of Moroccan origin. He has developed recurrent episodes of diffuse lymphadenopathies, renal failure and nephrotic syndrome. Renal biopsies showed membranous glomerulonephritis. Discussion and conclusion: The diagnostic approach of this atypical presentation is discussed in this case report as well as diagnostic criteria, therapeutic strategies, biomarkers and pathophysiology of IgG4-related disease. IgG4-related membranous glomerulonephritis is a well-established cause of membranous glomerulonephritis. It must be sought after in every patient with a previous diagnosis of IgG4-related disease and in every patient with this histological finding on renal biopsy. Corticoids are still the first-line treatment of IgG4-related disease. New therapeutic strategies are needed to avoid glucocorticoids long term side-effects. Interestingly, the patient was prescribed cyclophosphamide in addition to glucocorticoids for an immune thrombocytopenia. This treatment had a very good impact on his IgG4-related disease. [less ▲]

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See detailTraduction en français du "back pain attitudes questionnaire" et étude de ses qualités métrologiques
Demoulin, Christophe ULiege; hALLEUX, V.; DARLOW, B. et al

in Kinesitherapie Revue (2017, April), 184

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See detailÉtude du degré de satisfaction de patients lombalgiques au sujet de la brochure éducative « PAIN fundamentals »
Demoulin, Christophe ULiege; Blanc, A.; Wolfs, Sébastien ULiege et al

in Kinesitherapie Revue (2017, April), 184

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See detailContrôle du mouvement lombopelvien et football
Grosdent, Stéphanie ULiege; Demoulin, Christophe ULiege; Cortès Flores, A. et al

in Kinesitherapie Revue (2017, April), 184

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