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See detailA method for encoding Egyptian quadrats in Unicode
Glass, Andrew; Hafemann, Ingelore; Nederhof, Mark-Jan et al

Computer development (2017)

The proposal to encode three control characters for Egyptian Hieroglyphs was accepted at the February 2016 UTC meeting. Following that acceptance some members of the Egyptological community raised ... [more ▼]

The proposal to encode three control characters for Egyptian Hieroglyphs was accepted at the February 2016 UTC meeting. Following that acceptance some members of the Egyptological community raised concerns that the accepted controls were insufficient for their requirements. This led to a series of discussions and document submissions between specialists and implementers that explored the issues relating to encoding the quadrat structures that are an inherent feature of Egyptian Hieroglyphic writing. The present document combines expert input on Egyptian Hieroglyphs and a detailed exploration of possible solutions. It does not attempt to summarize or repeat arguments and details from earlier documents. Cross-references to earlier submissions are provided where appropriate. The result is a draft proposal for a system of controls that will enable plain text encoding of Egyptian Hieroglyphs in quadrats. [less ▲]

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See detailShape-memory polymers: principles and applications
Defize, Thomas ULg

Scientific conference (2017, April 26)

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See detailPressure flaking to serrate bifacial points for the hunt during the MIS5 at Sibudu Cave (South Africa)
Rots, Veerle ULg; Lentfer, Carol ULg; Schmid, Viola C. et al

in PLoS ONE (2017), 12(4), 0175151

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See detailLe financement des cultes selon Gwendolyn Rutten
Husson, Jean-François ULg

Article for general public (2017)

Analysis of the proposal from the chairwoman of the Flemish liberal party aiming at suppressing public finance for churches and philosophical organisations.

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See detailUtilisation du D-galactose et du D-tagatose chez Bacillus sp.: Etude des protéines GalM et PBP4a de B. subtilis et B. amyloliquefaciens et Etude de la voie catabolique PTS-dépendante du D-tagatose chez B. licheniformis.
Van der Heiden, Edwige ULg

Doctoral thesis (2017)

Cette thèse s’intéresse à la métabolisation de deux sources de carbones, le galactose et le tagatose, dans des souches du genre Bacillus. La première partie de la thèse vise à montrer le rôle de GalM, une ... [more ▼]

Cette thèse s’intéresse à la métabolisation de deux sources de carbones, le galactose et le tagatose, dans des souches du genre Bacillus. La première partie de la thèse vise à montrer le rôle de GalM, une galactose mutarotase, dans la métabolisation du galactose chez B. subtilis ATCC 21332 et B. amyloliquefaciens FZB42. Le gène galM est organisé en opéron avec le gène dacC qui code pour un PBP de faible poids moléculaire, le PBP4a. Des mutants ponctuels et de délétion ont été générés dans le but d’étudier l’implication des produits de cet opéron dans la formation de biofilms in vitro, dans le remodelage de la paroi bactérienne et dans la colonisation de racines de plantes (plants de tomate et Arabidopsis thaliana). Une différence significative de colonisation a été mise en évidence entre la souche sauvage de B. amyloliquefaciens FZB42 et son double mutant uniquement sur les racines de plants de tomate. Toutefois, il pourrait s’agir d’un effet indirect lié à la méthode. Après analyse des muropeptides composant le peptidoglycane isolé en phase végétative, aucun rôle in vivo n’a pu être attribué au PBP4a. Cependant, l’attachement de cette protéine à la membrane de la bactérie a pu être mis en évidence. Une couronne de charges positives en surface du domaine II du PBP4a est responsable de cette localisation. La seconde partie de la thèse présente la voie de métabolisation du tagatose découverte chez B. licheniformis. Cette source de carbone est transportée et phosphorylée par les composants du système phosphotransférase (PTS) : EIIAT AG (TagM) et EIIBCT AG (TagL). La fonctionnalité du cluster de gènes identifié dans le génome de la bactérie a été démontrée par des expériences de supplémentation dans deux souches initialement incapables de métaboliser cette source de carbone : B. subtilis et E. coli. Le tagatose est phosphorylé durant son transport au niveau du carbone C1. Le tagatose-1-phosphate, présent principalement sous la forme -pyranose, est ensuite phosphorylé par l’enzyme TagK, une tagatose-1-phosphate kinase. Les paramètres cinétiques de l’enzyme ont été déterminés et la spécificité en faveur du tagatose-1-phosphate a été démontrée. Le tagatose 1,6-bisphosphate généré par TagK est hydrolysé en DHAP et G3P par GatY, une tagatose 1,6-bisphosphate aldolase de classe II. [less ▲]

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See detailGlobal approach for the validation of an in-line Raman spectroscopic method to determine the API content in real-time during a hot-melt extrusion process
Netchacovitch, Lauranne ULg; Thiry, Justine ULg; De Bleye, Charlotte ULg et al

in Talanta (2017), 171

Since the Food and Drug Administration (FDA) published a guidance based on the Process Analytical Technology (PAT) approach, real-time analyses during manufacturing processes are in real expansion. In ... [more ▼]

Since the Food and Drug Administration (FDA) published a guidance based on the Process Analytical Technology (PAT) approach, real-time analyses during manufacturing processes are in real expansion. In this study, in-line Raman spectroscopic analyses were performed during a Hot-Melt Extrusion (HME) process to determine the Active Pharmaceutical Ingredient (API) content in real-time. The method was validated based on a univariate and a multivariate approach and the analytical performances of the obtained models were compared. Moreover, on one hand, in-line data were correlated with the real API concentration present in the sample quantified by a previously validated off-line confocal Raman microspectroscopic method. On the other hand, in-line data were also treated in function of the concentration based on the weighing of the components in the prepared mixture. The importance of developing quantitative methods based on the use of a reference method was thus highlighted. The method was validated according to the total error approach fixing the acceptance limits at ± 15% and the α risk at ± 5%. This method reaches the requirements of the European Pharmacopeia norms for the uniformity of content of single-dose preparations. The validation proves that future results will be in the acceptance limits with a previously defined probability. Finally, the in-line validated method was compared with the off-line one to demonstrate its ability to be used in routine analyses. [less ▲]

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See detailSize and shape variations of the bony components of sperm whale cochleae
Schnitzler, Joseph ULg; Frederich, Bruno ULg; Früchtnicht, Sven et al

in Scientific Reports (2017), 7

Several mass strandings of sperm whales occurred in the North Sea during January and February 2016. Twelve animals were necropsied and sampled around 48h after their discovery on German coasts of ... [more ▼]

Several mass strandings of sperm whales occurred in the North Sea during January and February 2016. Twelve animals were necropsied and sampled around 48h after their discovery on German coasts of Schleswig Holstein. The present study aims to explore the morphological variation of the primary sensory organ of sperm whales, the left and right auditory system, using high-resolution computerised tomography imaging. We performed a quantitative analysis of size and shape of cochleae using landmark-based geometric morphometrics to reveal inter-individual anatomical variations. A hierarchical cluster analysis based on thirty-one external morphometric characters classified these 12 individuals in two stranding clusters. A relative amount of shape variation could be attributable to geographical differences among stranding locations and clusters. Our geometric data allowed the discrimination of distinct bachelor schools among sperm whales that stranded on German coasts. We argue that the cochleae are individually shaped, varying greatly in dimensions and that the intra-specific variation observed in the morphology of the cochleae may partially reflect their affiliation to their bachelor school. There are increasing concerns about the impact of noise on cetaceans and describing the auditory periphery of odontocetes is a key conservation issue to further assess the effect of noise pollution. [less ▲]

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See detailDes activités pour nos aînés? Oui! Mais pas n’importe lesquelles!
Missotten, Pierre ULg; Clesse, Audrey ULg

Conference given outside the academic context (2017)

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See detailOn a conjecture about regularity and l-abelian complexity
Vandomme, Elise ULg

Conference (2017, April 25)

A natural generalization of automatic sequences over an infinite alphabet is given by the notion of k-regular sequences, introduced by Allouche and Shallit in 1992. The k-regularity of a sequence provides ... [more ▼]

A natural generalization of automatic sequences over an infinite alphabet is given by the notion of k-regular sequences, introduced by Allouche and Shallit in 1992. The k-regularity of a sequence provides us with structural information about how the different terms are related to each other. We show that a sequence satisfying a certain symmetry property is 2-regular. We apply this theorem to develop a general approach for studying the l-abelian complexity of 2-automatic sequences. In particular, we prove that the period-doubling word and the Thue–Morse word have 2-abelian complexity sequences that are 2-regular. The computation and arguments leading to these results fit into a quite general scheme that can be used to obtain additional regularity results. This supports the conjecture that the l-abelian complexity of a $k$-automatic sequence is a k-regular sequence. [less ▲]

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See detailWhat are the HRS4R benefits/impact for the institutions and researchers?
Halleux, Isabelle ULg

Scientific conference (2017, April 25)

This presentation aims to share the experience of the University of Liege that was awared the "HR excellence in research" logo by the EU in 2011. This lead the institution to develop an action plan for ... [more ▼]

This presentation aims to share the experience of the University of Liege that was awared the "HR excellence in research" logo by the EU in 2011. This lead the institution to develop an action plan for enhancing the working conditions of the researchers, to open positions to foreign researchers and to offer them training as services for their career development. [less ▲]

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See detailDetermining fine population structure using iterative pruning
Chaichoompu, Kridsadakorn ULg; Yazew, Fentaw Abegaz; Tongsima, Sissades et al

Poster (2017, April 25)

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See detailMultiple Semantic Priming and Latin Sequential Collocations : when Text Linguistics and Language Learning meet Cognitive Psychology
Lavigne, Frederic; Longrée, Dominique ULg; Mellet, Sylvie

Conference (2017, April 25)

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See detailThe prosumers and the grid
Gautier, Axel ULg

Scientific conference (2017, April 25)

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See detailResolved astrometric orbits of ten O-type binaries
Le Bouquin, J.-B.; Sana, H.; Gosset, Eric ULg et al

in Astronomy and Astrophysics (2017), 601

Our long term aim is to derive model-independent stellar masses and distances for long period massive binaries by combining apparent astrometric orbit with double-lined radial velocity amplitudes (SB2 ... [more ▼]

Our long term aim is to derive model-independent stellar masses and distances for long period massive binaries by combining apparent astrometric orbit with double-lined radial velocity amplitudes (SB2). We follow-up ten O+O binaries with AMBER, PIONIER and GRAVITY at the VLTI. Here, we report about 130 astrometric observations over the last 7 years. We combine this dataset with distance estimates to compute the total mass of the systems. We also compute preliminary individual component masses for the five systems with available SB2 radial velocities. Nine over the ten binaries have their three dimensional orbit well constrained. Four of them are known colliding wind, non-thermal radio emitters, and thus constitute valuable targets for future high angular resolution radio imaging. Two binaries break the correlation between period and eccentricity tentatively observed in previous studies. It suggests either that massive star formation produce a wide range of systems, or that several binary formation mechanisms are at play. Finally, we found that the use of existing SB2 radial velocity amplitudes can lead to unrealistic masses and distances. If not understood, the biases in radial velocity amplitudes will represent an intrinsic limitation for estimating dynamical masses from SB2+interferometry or SB2+Gaia. Nevertheless, our results can be combined with future Gaia astrometry to measure the dynamical masses and distances of the individual components with an accuracy of 5 to 15\%, completely independently of the radial velocities. [less ▲]

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See detailReconstructions of the 1900–2015 Greenland ice sheet surface mass balance using the regional climate MAR model
Fettweis, Xavier ULg; Box, Jason; Agosta, Cécile ULg et al

in Cryosphere (The) (2017), 11

With the aim of studying the recent Greenland ice sheet (GrIS) surface mass balance (SMB) decrease relative to the last century, we have forced the regional climate MAR (Modèle Atmosphérique Régional ... [more ▼]

With the aim of studying the recent Greenland ice sheet (GrIS) surface mass balance (SMB) decrease relative to the last century, we have forced the regional climate MAR (Modèle Atmosphérique Régional; version 3.5.2) model with the ERA-Interim (ECMWF Interim Re-Analysis; 1979–2015), ERA-40 (1958–2001), NCEP–NCARv1 (National Centers for Environmental Prediction–National Center for Atmospheric Research Reanalysis version 1; 1948–2015), NCEP–NCARv2 (1979–2015), JRA-55 (Japanese 55-year Reanalysis; 1958–2014), 20CRv2(c) (Twentieth Century Reanalysis version 2; 1900–2014) and ERA-20C (1900–2010) reanalyses. While all these forcing products are reanalyses that are assumed to represent the same climate, they produce significant differences in the MAR-simulated SMB over their common period. A temperature adjustment of +1 °C (respectively −1 °C) was, for example, needed at the MAR boundaries with ERA-20C (20CRv2) reanalysis, given that ERA-20C (20CRv2) is ∼ 1 °C colder (warmer) than ERA-Interim over Greenland during the period 1980–2010. Comparisons with daily PROMICE (Programme for Monitoring of the Greenland Ice Sheet) near-surface observations support these adjustments. Comparisons with SMB measurements, ice cores and satellite-derived melt extent reveal the most accurate forcing datasets for the simulation of the GrIS SMB to be ERA-Interim and NCEP–NCARv1. However, some biases remain in MAR, suggesting that some improvements are still needed in its cloudiness and radiative schemes as well as in the representation of the bare ice albedo. Results from all MAR simulations indicate that (i) the period 1961–1990, commonly chosen as a stable reference period for Greenland SMB and ice dynamics, is actually a period of anomalously positive SMB (∼ +40 Gt yr−1) compared to 1900–2010; (ii) SMB has decreased significantly after this reference period due to increasing and unprecedented melt reaching the highest rates in the 120-year common period; (iii) before 1960, both ERA-20C and 20CRv2-forced MAR simulations suggest a significant precipitation increase over 1900–1950, but this increase could be the result of an artefact in the reanalyses that are not well-enough constrained by observations during this period and (iv) since the 1980s, snowfall is quite stable after having reached a maximum in the 1970s. These MAR-based SMB and accumulation reconstructions are, however, quite similar to those from Box (2013) after 1930 and confirm that SMB was quite stable from the 1940s to the 1990s. Finally, only the ERA-20C-forced simulation suggests that SMB during the 1920–1930 warm period over Greenland was comparable to the SMB of the 2000s, due to both higher melt and lower precipitation than normal. [less ▲]

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See detailBlended learning - Pedagogical success factors and development methodology
Verpoorten, Dominique ULg; Parlascino, Emmanuelle ULg; André, Marine ULg et al

Report (2017)

Pedagogical factors that make a blended learning course a success are numerous. But the most critical one is, for blended courses owners, to rely on a safe development methodology. This is why this ... [more ▼]

Pedagogical factors that make a blended learning course a success are numerous. But the most critical one is, for blended courses owners, to rely on a safe development methodology. This is why this document presents as a handbook usable as a ready reference for guiding teachers through the different steps and attention points to be considered in the making of their blended set up. [less ▲]

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See detailThaw pond dynamics and carbon emissions in a Siberian lowland tundra landscape
Van Huissteden, J.; Heijmans, M.M.P.D.; Dean, J. et al

Poster (2017, April 25)

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See detailHow phosphorus limitation can control climatic gas sources and sinks
Gypens, N; Borges, Alberto ULg; Ghyoot, C

Poster (2017, April 25)

Detailed reference viewed: 10 (2 ULg)