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See detailMethionine-derived Schiff base as selective fluorescent “turn-on”chemosensor for Zn2+in aqueous medium and its application in livingcells imaging
Faiz-Ur-Rahman; Ali, Amjad ULg; Rong Guo et al

in Sensors and Actuators B: Chemical (2015)

tWe describe the quantitative synthesis of a Schiff base derived from methionine and salicylaldehyde(SMSB) which displayed turn-on selective fluorescent chemo-sensing properties for Zn2+in bufferedCH3CN ... [more ▼]

tWe describe the quantitative synthesis of a Schiff base derived from methionine and salicylaldehyde(SMSB) which displayed turn-on selective fluorescent chemo-sensing properties for Zn2+in bufferedCH3CN/H2O (1:1) solution. In physiological pH (7.2 buffered) SMSB exhibited high selectivity and sen-sitivity toward Zn2+over the other selected metal ions. Upon the addition of Zn2+33 folds of emissionenhancement was observed in SMSB and limit of detection (CL) for Zn2+was found to be 5.0 × 10−7M. Thisbinding phenomenon was studied by1H NMR and HR-MS analysis. Mass spectrometry analysis revealedthat SMSB interacts with Zn2+and form a 1:1 complex, also confirmed by Job’s plot. This probe wascompletely retrieved by adding EDTANa2solution, exhibited a fluorescent quenching effect by removingZn2+from the sensor. SMSB was observed to have a good tolerance for fluorescence detection of Zn2+in pH range 6–10. Furthermore it is successfully investigated for living cells imaging using MCF-7 cells.Combine experimental results indicated SMSB to be a useful and powerful chemosensing probe for Zn2+in water as well as in living cells. [less ▲]

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See detailQuand science politique et droit dialoguent : quelle typologie des instruments mémoriels en fonction du degré de contrainte ?
Grandjean, Geoffrey ULg

Conference (2015, February 07)

Envisager les études sur la mémoire comme sous-champ de la science politique francophone ouvre des pistes enrichissantes pour les politologues, notamment lorsqu’ils sont amenés à analyser les instruments ... [more ▼]

Envisager les études sur la mémoire comme sous-champ de la science politique francophone ouvre des pistes enrichissantes pour les politologues, notamment lorsqu’ils sont amenés à analyser les instruments mémoriels régissant un ou plusieurs système(s) politique(s). Dans cette perspective, la communication vise à présenter, d’un point de vue épistémologique, les apports découlant de l’interaction entre les sciences politique et juridique dans le processus de consolidation des études sur la mémoire comme sous-champ disciplinaire de la science politique. Plus précisément, la communication vise à offrir une typologie des instruments mémoriels en fonction du degré de contrainte et d’imposition d’une mémoire officielle. Par exemple, une résolution adoptée par une assemblée législative est faiblement contraignante alors qu’une loi réprimant le négationnisme impose à la fois une mémoire officielle tout en sanctionnant pénalement les citoyens qui ne la respectent pas. La typologie passe en revue les multiples instruments mémoriels pouvant être adoptés par les autorités publiques : résolution, loi déclarative, loi pénale, plan de commémorations ou encore mise en valeur d’un lieu de mémoire. L’accent est mis sur les instruments mémoriels de deux pays francophones : la Belgique et la France. Au final, cette communication permet d’insister sur l’apport de la science politique en analysant l’exercice de prérogatives de puissance publique et sur l’apport de la science juridique en classifiant les types d’instruments mémoriels en fonction du degré de contrainte ; tout en faisant dialoguer des cas d’étude différents. [less ▲]

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See detailThe return of Turkey to the Western Balkans: a challenge or an opportunity for the European Union ?
Lika, Liridon ULg

Conference (2015, February 07)

In the new Turkish doctrine, besides the great interests in Central Asia, Middle East, Africa and the Caucasus, the Balkans are also important. Turkey is making great efforts to play a greater role on the ... [more ▼]

In the new Turkish doctrine, besides the great interests in Central Asia, Middle East, Africa and the Caucasus, the Balkans are also important. Turkey is making great efforts to play a greater role on the international scene and creates its area of interest, especially where the links of Ottoman legacy can help. Although it is defined as a peaceful power in the region, some describe it as neo-ottoman, a term rejected by the Turkish authorities because of its possible imperialist connotation. This paper aims precisely to study the return of Turkey to the Balkans. Our central question is: what is the purpose of the Turkish foreign policy in the Western Balkans? Related issues will be addressed such as: is there a competition between Turkey and the European Union in this area? What are the specifics of Turkish foreign policy? In order to explore these research questions, this study focuses on the concept of soft power through which Turkey extends its power. Indeed, the Turkish government imposes itself on the Balkans not by force but with the help of economics, diplomacy, trade, culture and religion. Following the crisis in the EU, causing the collapse of Western investment and a relative decrease of attraction for the Balkans, Turkey has taken advantage of the situation in order to increase its influence in all areas. This contribution will proceed in three stages. Firstly, we will make an analysis of the authors of soft power to think about the character of the new Turkish geopolitical doctrine. Secondly, we are going to apply this theoretical framework to the case study identified, namely the influence of Turkey in the Western Balkan countries. Finally, we will show if exists a competition or a cooperation between Turkey and European Union in the Western Balkans. [less ▲]

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See detailIn situ investigation of scCO2 assisted impregnation of drug into polymer by high pressure FTIR micro-spectroscopy
Champeau, Mathilde ULg; Thomassin, Jean-Michel ULg; Jérôme, Christine ULg et al

in Analyst (2015), 140(3), 869-879

An original experimental set-up combining a FTIR microscope with a high pressure cell has been built in order to analyze in-situ the impregnation of solute into microscopic polymer samples, such as fibers ... [more ▼]

An original experimental set-up combining a FTIR microscope with a high pressure cell has been built in order to analyze in-situ the impregnation of solute into microscopic polymer samples, such as fibers or films, subjected to supercritical CO2. Thanks to this experimental set-up, key factors governing the impregnation process can be simultaneously followed such as the swelling of the polymeric matrix, the CO2 sorption, the kinetic of impregnation and the drug loading into the matrix. Moreover, the solute/polymer interactions and the speciation of the solute can be analyzed. We have monitored in situ the impregnation of aspirin and ketoprofen into PEO (Polyethylene Oxide) platelets at T=40°C and P=5; 10 and 15 MPa. The kinetic of impregnation of aspirin was quicker than the one of ketoprofen and the final drug loading was also higher in case of aspirin. Whereas the CO2 sorption and the PEO swelling remain constant when PEO is just subjected to CO2 under isobaric conditions, we noticed that both parameters can increase while the drug impregnates PEO. Coupling these results with DSC measurements, we underlined the plasticizing effect of the drug that also leads to decrease the crystallinity of PEO in situ thus favoring the sorption of CO2 molecules into the matrix and the swelling of the matrix. The plasticizing effect increases with the drug loading. Finally, the speciation of drug was investigated considering the shift of the carboxyl bands of the drugs. Both drugs were found to be mainly homogeneously dispersed into PEO. [less ▲]

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See detailLa pérennisation des partenariats publics-privés dans le champ de l’emploi : entre application, interprétation et ajustement du cadre réglementaire
Remy, Céline ULg; Gérard, Julie ULg; Beuker, Laura ULg

Conference (2015, February 07)

Dans une perspective de gestion mixte du marché du travail, les services publics de l’emploi sont invités, par la Convention 181 de l’OIT de 1997, à déléguer et à confier l’exploitation et la gestion de ... [more ▼]

Dans une perspective de gestion mixte du marché du travail, les services publics de l’emploi sont invités, par la Convention 181 de l’OIT de 1997, à déléguer et à confier l’exploitation et la gestion de leurs activités à des opérateurs privés de service, dans le cadre d’une entente contractuelle. Alors que les modalités de la collaboration (telles que le public-cible, le type et le nombre d’accompagnements dispensés, les résultats à atteindre, etc.) sont fixées, initialement, par les services publics de l’emploi, elles sont ensuite mises en pratique par les diverses parties-prenantes du partenariat. Les acteurs publics et privés exploitent la part de latitude inhérente à leur fonction pour interpréter et ajuster les termes du contrat ou pour pouvoir réaliser leur mission d’accompagnement des demandeurs d’emploi. Partant du postulat que la règle est incomplète, notre objectif est d’analyser la mise en œuvre du partenariat en saisissant les arguments avancés par les acteurs pour justifier et légitimer leurs actions. À partir de cette analyse, nous montrerons que les acteurs du partenariat doivent interpréter les règles – écart entre le travail prescrit et le travail effectivement presté – dans leurs pratiques quotidiennes. Agissant comme des « pseudo » street-level bureaucrats, ces derniers usent de leur pouvoir pour ajuster les règles. En outre, il semblerait que ces pratiques d'indiscipline permettent, en réalité, de maintenir les relations partenariales entre services publics de l’emploi et opérateurs privés, et d’œuvrer, in fine, à la pérennisation de celles-ci dans le champ de l’emploi. Nous appuierons notre analyse sur un matériau empirique composé d’observations participantes et d’entretiens semi-directifs réalisés auprès des parties-prenantes des PPP, situés en Belgique francophone. [less ▲]

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See detailIntérêt du signal T2 des adénomes hypophysaires à GH traités par analogues de la somatostatine - premiers résultats de l'étude IRMA#2
Potorac, Iulia ULg; PETROSSIANS, Patrick ULg; Daly, Adrian ULg et al

in Symposium "Perspectives in Endocrinology" - 5ème édition (2015, February 07)

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See detailNouvelle classification des acro-gigantismes
Rostomyan, Liliya ULg; Beckers, Albert ULg

in Symposium "Perspectives in Endocrinology" - 5ème édition (2015, February 07)

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See detailA novel mutation of the luteinizing hormone/choionic gonadotrophin receptor gene leading to Leydig cell hypoplasia type I
Potorac, Iulia ULg; Rivero-Müller, A; Pintiaux, Axelle ULg et al

in Symposium "Perspectives in Endocrinology" - 5ème édition (2015, February 07)

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See detailRevisiting the SN1987A gamma-ray limit on ultralight axion-like particles
Payez, Alexandre ULg; Evoli, Carmelo; Fischer, Tobias et al

in Journal of Cosmology and Astroparticle Physics [= JCAP] (2015), 2015(02), 006

We revise the bound from the supernova SN1987A on the coupling of ultralight axion-like particles (ALPs) to photons. In a core-collapse supernova, ALPs would be emitted via the Primakoff process, and ... [more ▼]

We revise the bound from the supernova SN1987A on the coupling of ultralight axion-like particles (ALPs) to photons. In a core-collapse supernova, ALPs would be emitted via the Primakoff process, and eventually convert into gamma rays in the magnetic field of the Milky Way. The lack of a gamma-ray signal in the GRS instrument of the SMM satellite in coincidence with the observation of the neutrinos emitted from SN1987A therefore provides a strong bound on their coupling to photons. Due to the large uncertainty associated with the current bound, we revise this argument, based on state-of-the-art physical inputs both for the supernova models and for the Milky-Way magnetic field. Furthermore, we provide major amendments, such as the consistent treatment of nucleon-degeneracy effects and of the reduction of the nuclear masses in the hot and dense nuclear medium of the supernova. With these improvements, we obtain a new upper limit on the photon-ALP coupling: g_{a\gamma} < 5.3 x 10^{-12} GeV^{-1}, for m_a < 4.4 x 10^{-10} eV, and we also give its dependence at larger ALP masses. Moreover, we discuss how much the Fermi-LAT satellite experiment could improve this bound, should a close-enough supernova explode in the near future. [less ▲]

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See detailLa construction de la puissance brésilienne
Santander, Sébastian ULg

Scientific conference (2015, February 06)

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See detailSingle Wavelength Coarse Phasing In Segmented Telescopes
Simar, Juan Felipe ULg

in Applied Optics (2015), 54

Space observations of fainter and more distant astronomical objects constantly require telescope primary mirrors with a larger size. The diameter of monolithic primary mirrors is limited to 10 m because ... [more ▼]

Space observations of fainter and more distant astronomical objects constantly require telescope primary mirrors with a larger size. The diameter of monolithic primary mirrors is limited to 10 m because of manufacturing limitations. For space telescopes, the primary mirrors are limited to less than 5 m due to fairing capacity. Segmented primary mirrors thus constitute an alternative solution to deal with the steadily increase of the primary mirror size. The optical path di erence between the individual segments must be close to zero (few nm) in order to be di raction limited. We propose in this paper a new inter-segment piston sensor based on coherence measurement of a star image. This sensor is intended to be used in the co-phasing system of future segmented mirrors. [less ▲]

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See detailComment les disciplines se reconstruisent dans des environnements hybrides et dynamiques
Fallon, Catherine ULg; Thoreau, François ULg

Scientific conference (2015, February 06)

Les chercheurs en sciences politiques et sociales, voire les philosophes politiques, sont de plus en plus souvent « embarqués » dans des projets résolument transdisciplinaires, portés par les groupes de ... [more ▼]

Les chercheurs en sciences politiques et sociales, voire les philosophes politiques, sont de plus en plus souvent « embarqués » dans des projets résolument transdisciplinaires, portés par les groupes de recherche de différentes disciplines, engagés dans les développement scientifico-technologiques les plus pointus, que ce soit dans le secteur des nanotechnologies ou des biotechnologies médicales (pour citer deux exemples récents,Thoreau 2013) . Cet article prend comme point de départ un projet pluriannuel qui a obtenu des subsides pour plonger pendant une longue période trois chercheurs (philosophe, anthropologue, politologue) dans un centre de recherche en génomique humaine appliquée, installé dans une aile du Centre-Hospitalo-Universitaire. En tant que coordinateurs de ce projet, nous voulons aborder ab initio (1) la question des conditions d’exercice de notre démarche de terrain et (2) les conditions de notre service en tant que politologues au fil de cette trajectoire. [less ▲]

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See detailComprendre les programmes électoraux : comparaison des méthodes d’encodage manuel et automatique
Piet, Grégory ULg; Dandoy, Régis; Joly, Jeroen

Conference (2015, February 06)

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See detailMédias et dette wallonne: polémique autour d'un indicateur de finances publiques
Piron, Damien ULg

Conference (2015, February 06)

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See detailThe phosphorylation of RelA on Ser547 does not modulate NF-kB activation after TNFa treatment like after a genotoxic stress
Trussart, Charlotte ULg; Orban, Tanguy ULg; Di Valentin, Emmanuel ULg et al

Poster (2015, February 06)

NF-kB controls the expression of hundred of genes involved in inflammatory and innate responses, proliferation, survival, cancer initiation and progression. Numerous post-translational modifications of ... [more ▼]

NF-kB controls the expression of hundred of genes involved in inflammatory and innate responses, proliferation, survival, cancer initiation and progression. Numerous post-translational modifications of p65 modulating NF-kB transcriptional activity are known. We identified Ser547 as a new site of p65 phosphorylation targeted by ATM kinase, which coordinates the “DNA Damage Response” pathway in the event of DNA double-strand breaks. We demonstrated that the phosphorylation of Ser547 regulates the transcription of a sub-set of NF-κB dependent genes after genotoxic stress by modifying HDAC1 recruitment(1). Presently, we are investigating the role of this specific phosphorylation in an inflammatory context. We observe that the mutations of p65 (S547A or S547D) also affect the transcriptional potential of the NF-κB in a promoter specific manner after an exposition to TNFα and H2O2. The study of the molecular mechanism of this regulation after TNFα and H2O2 exposition are both in progress. [less ▲]

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See detailA mixed integer nonlinear programming bi-objective model for intermodal network design
Mostert, Martine ULg; Caris, An; Limbourg, Sabine ULg

Conference (2015, February 05)

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See detailOpinions, attitudes et comportements politiques. Notes de cours
Grandjean, Geoffrey ULg

Learning material (2015)

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See detailOpinions, attitudes et comportements politiques. Dossier de documentation
Grandjean, Geoffrey ULg

Learning material (2015)

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See detailPolitical Opinions, Attitudes and Behaviours
Grandjean, Geoffrey ULg

Learning material (2015)

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