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See detailBoucle et répétition : musique, littérature, arts visuels
Belloi, Livio ULg; Delville, Michel ULg; Levaux, Christophe ULg et al

Book published by Presses Universitaires de Liège (in press)

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See detailBattista Guarino. Sermone del cane e del cavallo
Valenti, Gianluca ULg

Book published by Salerno Editrice (in press)

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See detailSubmarine Paleo-earthquake record of the Cinarcik segment of the North Anatolian Fault in the Marmara Sea (Turkey)
Drab, Laureen; Hubert, Aurelia ULg; Carlut, Julie et al

in Bulletin Seismological Society of America (in press)

The submarine part of the North Anatolian Fault (NAF) in the Marmara Sea is a significant hazard for the city of Istanbul (Turkey). The use of paleoseismological data to provide an accurate seismic risk ... [more ▼]

The submarine part of the North Anatolian Fault (NAF) in the Marmara Sea is a significant hazard for the city of Istanbul (Turkey). The use of paleoseismological data to provide an accurate seismic risk assessment for the area is constrained by the fact that the NAF system is submarine near Istanbul; thus a history of paleoearthquakes can be inferred only by using sediment cores. Here a record of turbidites was obtained in two cores and used to reconstruct the earthquake history along a main branch of the NAF, the Cinarcik Segment. Kullenberg core Klg04 (4 m long) was collected during Marmarascarps mission from a berm north of the fault and a second core (Klg03, 3.5 m long) was positioned in the Cinarcik Basin, 3 km south of the fault. Sedimentary sequences in the two cores were correlated using variations in Ca/Ti ratio, which reflect the local aquatic productivity compared with more terrigenous input. The turbidites between the two cores were then classified to distinguish the synchronous ones from the other ones. Radionuclide measurements suggest that the most recent turbidite recorded in both cores was triggered by the M=7.3 1894 earthquake. We conclude that the turbidites are earthquake-generated, based on: 1) their distinctive sedimentological and geochemical signatures, previously described and applied in the Marmara Sea; 2) the correlation of turbidites between cores at berm and basin sites; 3) the match of the most recent turbidites with a 19th century historical earthquake; and 4) the elimination of others processes. Because of its specific geomorphological location, core Klg04 likely records only mass wasting events related to the rupture on the Cinarcik Segment. To date older turbidites, we used 14C and paleomagnetic data to build an OxCal age model with a local reservoir correction (ΔR) of 400±50 yr. The Cinarcik Segment is found to have ruptured in AD1894, AD1509, sometime in the 14th century, AD989, AD740 and in the 5th century and have a mean recurrence interval of rupture between 243 and 396 years. Following the age model obtained we finally used the earthquake record history of the Cinarcik Segment to infer the rupture history of adjacent segments of the North Anatolian Fault during six earthquake cycles over the past 1500 years. [less ▲]

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See detailNon-adiabatic study of the Kepler subgiant KIC 6442183
Grosjean, Mathieu ULg; Dupret, Marc-Antoine ULg; Belkacem, Kevin et al

in The Space Photometry Revolution CoRoT Symposium 3, Kepler KASC-7 joint meeting (in press)

Thanks to the precision of Kepler observations, [3] were able to measure the linewidth and amplitude of individual modes (including mixed modes) in several sub- giant power spectra. We perform a forward ... [more ▼]

Thanks to the precision of Kepler observations, [3] were able to measure the linewidth and amplitude of individual modes (including mixed modes) in several sub- giant power spectra. We perform a forward modelling of a Kepler subgiant based on sur- face properties and observed frequencies. Non-adiabatic computations including a time- dependent treatment of convection give the lifetimes of radial and non-radial modes. Next, combining the lifetimes and inertias with a stochastic excitation model gives the ampli- tudes of the modes. We can now directly compare theoretical and observed linewidths and amplitudes of mixed-modes to obtain new constraints on our theoretical models. [less ▲]

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See detailRelire Durkheim à partir de Zola : Ce que le roman naturaliste fait à la sociologie du suicide de Durkheim
Ledent, David ULg

in Le suicide : question individuelle ou question sociétale ? (in press)

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See detailLe partage du sensible
Havelange, Carl ULg

in Fritz, Jean-Marie; Duhl, Olga (Eds.) Les cinq sens entre Moyen Age et Renaissance (in press)

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See detailAssociations of Plasma Concentrations of Dichlorodiphenyldichloroethylene and Polychlorinated Biphenyls with Prostate Cancer: A Case–Control Study in Guadeloupe (French West Indies)
Emeville, Elise; Giusti, Arnaud ULg; Coumoul, Xavier et al

in Environmental Health Perspectives (in press)

Background: Long-term exposure to persistent pollutants with hormonal properties (endocrine-disrupting chemicals, EDCs) may contribute to the risk of prostate cancer (PCa). However, epidemiological ... [more ▼]

Background: Long-term exposure to persistent pollutants with hormonal properties (endocrine-disrupting chemicals, EDCs) may contribute to the risk of prostate cancer (PCa). However, epidemiological evidence remains limited. Objectives: We investigated the relationship between PCa and plasma concentrations of universally widespread pollutants, in particular p,p’- dichlorodiphenyl dichloroethene (DDE) and the non-dioxin like polychlorinated biphenyl congener 153 (PCB153). Methods and Findings: We evaluated before treatment 576 men with newly diagnosed PCa and 655 controls in Guadeloupe (French West Indies). Exposure was analyzed according to case-control status. Associations were assessed by unconditional logistic regression analysis, controlling for confounding factors. Missing data were handled by multiple imputation. We estimated a significant positive association between DDE and PCa (adjusted odds ratio [OR] 1.53; 95% CI 1.02, 2.30 for the highest versus lowest quintile of exposure; PTrend= 0.01). PCB153 was inversely associated with PCa (OR 0.30; 95% CI 0.19, 0.47 for the highest versus lowest quintile of exposure values; PTrend<0.001). Also, PCB153 was more strongly associated to low-grade than high grade PCa. Conclusions: Associations of PCa with DDE and PCB153 were in opposite directions. This may reflect differences in the mechanisms of action of these EDCs, and although our findings need to be replicated in other populations, they are consistent with complex effects of EDCs on human health. [less ▲]

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See detailExplorer la banque de graines du sol pour mieux comprendre la dynamique de régénération des forêts tropicales africaines (synthèse bibliographique)
Douh, Chauvelin ULg; Daïnou, Kasso ULg; Loumeto, Jean Joël et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (in press), 18(4),

La banque de graines du sol des forêts denses humides africaines a été très peu étudiée, alors qu’elle pourrait jouer un rôle déterminant dans les cycles sylvigénétiques naturels. Elle pourrait également ... [more ▼]

La banque de graines du sol des forêts denses humides africaines a été très peu étudiée, alors qu’elle pourrait jouer un rôle déterminant dans les cycles sylvigénétiques naturels. Elle pourrait également être avantageusement utilisée dans les programmes de restauration, à l’instar de ce qui se fait sur d’autres continents. La présente synthèse bibliographique fait le point sur les connaissances actuelles relatives à la banque de graines du sol, en mettant l’accent sur le continent africain. Elle montre qu’une meilleure caractérisation de la banque de graines du sol des différentes communautés végétales constituerait une contribution notable pour la gestion durable des forêts tropicales d’Afrique. [less ▲]

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See detailCharacterizing the morphology of suburban settlements: a method based on a semi-automatic classification of building clusters
de Smet, Fabian; Teller, Jacques ULg

in Landscape Research (in press)

Urban sprawl is transforming our landscapes and rural areas at a spectacular pace. Measuring the strength of the phenomenon and proposing dynamic ways to delineate suburban areas have been the object of ... [more ▼]

Urban sprawl is transforming our landscapes and rural areas at a spectacular pace. Measuring the strength of the phenomenon and proposing dynamic ways to delineate suburban areas have been the object of much debate amongst scientists. The present article takes the view that, beyond measuring and delineating suburban areas, more efforts should be directed to qualifying the morphology of built settlements within these areas. Therefore it proposes a method based on a semi-automatic classification system of building clusters, designed to describe and interpret the phenomenon from a morphological perspective. This method is based on a combination of field surveys with numerical analyses of digital land cadastre maps. The application of this classification system to the suburban area around Liege reveals that, far from developing in a complete indifference of local conditions, contemporary suburban settlements are influenced by landscape structures inherited from the past. [less ▲]

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See detailThe Chronocultural Sequence of Belgian Complexes in the European Aurignacian Context
Flas, Damien ULg

in P@lethnology (in press), 6

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See detailUn contrat d'apprentissage du IIIe siècle avant notre ère : P.Heid. III 226
Ricciardetto, Antonio ULg

in Ricciardetto, Antonio; Marganne, Marie-Hélène (Eds.) Actes de la Journée d'étude internationale "En marge du Serment hippocratique : contrats et serments dans le monde gréco-romain" (in press)

Réexamen de l'unique contrat d'apprentissage de médecin connu à ce jour (P.Heid. III 226), daté des années 215/213 avant notre ère et de provenance inconnue. Considéré comme un faux par P. Sattler, son ... [more ▼]

Réexamen de l'unique contrat d'apprentissage de médecin connu à ce jour (P.Heid. III 226), daté des années 215/213 avant notre ère et de provenance inconnue. Considéré comme un faux par P. Sattler, son premier éditeur (1963), puis, comme un exercice scolaire (Fr. Uebel, 1965), ce document écrit en grec au verso d'un compte pour la construction d'un bâtiment (P. Heid. III 225, c. 250 av. J.-Chr.) est aussi le seul contrat d'apprentissage attesté pour l'époque ptolémaïque. [less ▲]

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See detailValidated ready-to-use GC-MS/MS method for dioxin analysis in food and feed following the new EU Regulations
L'Homme, Benjamin ULg; Sandy, Chris; Scholl, Georges ULg et al

in Organohalogen Compounds (in press)

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See detailA classification of barycentrically associative polynomial functions
Marichal, Jean-Luc; Mathonet, Pierre ULg; Tomaschek, Jörg

in Aequationes Mathematicae (in press)

We describe the class of polynomial functions which are barycentrically associative over an infinite commutative integral domain.

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See detailBiodistribution and radiation dosimetry for the novel SV2A radiotracer [18F]UCB-H: Firstin- human study.
Bretin, Florian ULg; Bahri, Mohamed Ali ULg; BERNARD, Claire ULg et al

in Molecular Imaging & Biology (in press)

Abstract- [18F]UCB-H is a novel radiotracer with a high affinity for SV2A, a protein expressed in synaptic vesicles. SV2A is the binding site of levetiracetam, a “first in class” antiepileptic drug with a ... [more ▼]

Abstract- [18F]UCB-H is a novel radiotracer with a high affinity for SV2A, a protein expressed in synaptic vesicles. SV2A is the binding site of levetiracetam, a “first in class” antiepileptic drug with a distinct but still poorly understood mechanism of action. The objective of this study was to determine the biodistribution and radiation dosimetry of [18F]UCB-H in a human clinical trial and to establish injection limits according to biomedical research guidelines. Additionally, the clinical radiation dosimetry results were compared to estimations in previously published preclinical data. Dynamic whole body PET/CT imaging was performed over approximately 110 minutes on five healthy male volunteers after injection of 144.5 ± 7.1 MBq (range, 139.1 – 156.5 MBq) of [18F]UCB-H. Major organs were delineated on CT images and time-activity curves were obtained from co-registered dynamic PET emission scans. Time-integrated activity coefficients were calculated as area under the curve using trapezoidal numerical integration. Urinary excretion data based on PET-activities including voiding was simulated using the dynamic bladder module of OLINDA/EXM. The radiation dosimetry was calculated using OLINDA/EXM. The effective dose to the OLINDA/EXM 70 kg standard male was 1.54E-02 ± 6.84E-04 mSv/MBq, with urinary bladder wall, gallbladder wall and the liver receiving the highest absorbed dose. The brain, the tracer’s main organ of interest, received an absorbed dose of 1.89E-02 ± 2.32E-03 mGy/MBq. This first human dosimetry study of [18F]UCB-H indicated that the tracer shows similar radiation burdens to widely used common clinical tracers. Single injections of at maximum 672 MBq for USA practice and 649 MBq for European practice keep radiation exposure below recommended limits. Recently published preclinical dosimetry data extrapolated from mice provided satisfactory prediction of total body and effective dose, but showed significant differences in organ absorbed doses compared to human data. [less ▲]

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See detailHow does governmental versus private venture capital backing affect a firm's efficiency? Evidence from Belgium
Alperovych; Hübner, Georges ULg; Lobet, Fabrice

in Journal of Business Venturing (in press)

We investigate the implications of venture capital (VC) investor type (government or private) on the operating efficiency of a sample of 515 Belgian portfolio firms up to 3 years after the investment. We ... [more ▼]

We investigate the implications of venture capital (VC) investor type (government or private) on the operating efficiency of a sample of 515 Belgian portfolio firms up to 3 years after the investment. We find that the government VC-backed firms display significant reductions in productivity. No significant differences in efficiency are found in firms backed by private VC compared with their non-VC-backed peers. Finally, significant reductions in efficiency exist in targets of government VC compared to their non-VC-backed peers. [less ▲]

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See detailClinical pharmacology of antifungal agents to overcome drug resistance in pediatric patients
STERGIOPOULOU, Theodouli ULg; Walsh, Thomas J.

in Expert opinion on pharmacotherapy (in press), 16(2), 213-26

INTRODUCTION: Antifungal resistance is an emerging problem that increases morbidity and mortality in immunosuppressed pediatric patients, who suffer from invasive fungal diseases. Optimal pharmacological ... [more ▼]

INTRODUCTION: Antifungal resistance is an emerging problem that increases morbidity and mortality in immunosuppressed pediatric patients, who suffer from invasive fungal diseases. Optimal pharmacological management is critical for the successful treatment of invasive fungal infections by resistant strains. AREAS COVERED: This paper reviews the mechanisms of resistance of different classes of antifungal agents and the current understanding of pediatric antifungal pharmacology for overcoming antifungal resistance in children based on laboratory and clinical studies in the English literature. The therapeutic choices against fungal pathogens with intrinsic or acquired resistance are further reviewed. EXPERT OPINION: There is a paucity of data in the pediatric population regarding the epidemiology of the resistant organisms to different antifungal agents. It is also unknown if there are more prevalent molecular mechanisms that promote antifungal resistance. Selection and dosages of the most effective antifungal agent for overcoming the antifungal resistance is crucial. However, there are limited studies guiding the optimal dosage and duration of treatment for management of emergent antifungal resistance. Further studies are warranted to elucidate the optimal pharmacology of the current antifungal agents against resistant organisms and to advance the development of new antifungal agents. [less ▲]

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See detailToward and old-growth concept for grasslands, savannas, and woodlands
Veldman, Joseph W; Buisson, Elise; Durigan, Giselda et al

in Frontiers in Ecology and the Environment (in press)

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See detailEnzymatic hydrolysis of softwood and hardwood regenerated celluloses
Jacquet, Nicolas ULg; Maniet, Guillaume ULg; Richel, Aurore ULg et al

in Current Chemical Biology (in press)

Regenerated celluloses from Kraft wood pulps (from hardwoods and softwoods) were hydrolysed by mean of cellulase of Trichoderma reesei. Our results highlighted that a 75% hydrolysis yield was reached for ... [more ▼]

Regenerated celluloses from Kraft wood pulps (from hardwoods and softwoods) were hydrolysed by mean of cellulase of Trichoderma reesei. Our results highlighted that a 75% hydrolysis yield was reached for hardwood regenerated cellulose (HRC) and 90% for softwood regenerated cellulose (SRC). Crystallinity indices from X-Ray diffraction patterns were used to measure hydrolysis rate of crystalline and amorphous regions. Addition of β-glucosidase to the enzymatic complex of Trichoderma reesei was confirmed to enhance yields of hydrolysis. [less ▲]

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See detail« À table ! ». Indexation et organisation des livres de cuisine aux 17e et 18e siècles
Colson, Maryse ULg

in Mathieu, Georges (Ed.) Les Tables des matières (in press)

Detailed reference viewed: 14 (3 ULg)