Last 7 days     Results 1401-1420 of 61537.   66 67 68 69 70 71 72 73 74 75 76   Integrating production scheduling and vehicle routing decisions at the operational decision level: A review and discussionMoons, Stef; Ramaekers, Katrien; Caris, An et alin Computers & Industrial Engineering (2017), 104Production scheduling and vehicle routing are two well-studied problems in literature. Although these supply chain functions are interrelated, they are often solved sequentially. This uncoordinated ... [more ▼]Production scheduling and vehicle routing are two well-studied problems in literature. Although these supply chain functions are interrelated, they are often solved sequentially. This uncoordinated approach can lead to suboptimal solutions. In the current competitive business environment, companies are searching for methods to save costs and improve their service level. Integrating production and distribution scheduling operations can be an approach to improve the overall performance. This paper focuses on integrated production-distribution operational level scheduling problems, which explicitly take into account vehicle routing decisions of the delivery process. Existing literature on integrated production scheduling and vehicle routing problems is reviewed and classified. Both the problem characteristics of mathematical models and the accompanying solution approaches are discussed to identify directions for further research. [less ▲]Detailed reference viewed: 21 (1 ULg) New computational method of the ball/race contacts transverse loads of high speed ball bearings without race control hypothesisServais, Christophe in Tribology International (2017)Some hypotheses are still necessary in order to access the ball bearing Newtonian equilibrium with quasi-static methods. Among these hypotheses are the values of the transverse loads within ball/race ... [more ▼]Some hypotheses are still necessary in order to access the ball bearing Newtonian equilibrium with quasi-static methods. Among these hypotheses are the values of the transverse loads within ball/race contacts. Those loads are due to the gyroscopic torques. Nowadays, the transverse loads are estimated without any equilibrium criterion by the specialized literature. Moreover, the race control assumption is often employed in addition to the hypotheses made about the transverse loads. The paper describes a new method to compute the transverse loads without using the race control assumption. Then, a correlation between the ball bearing kinematics and the transverse loads is established. It leads to an accurate and efficient computational method to access the Newtonian equilibrium of high speed ball bearings. [less ▲]Detailed reference viewed: 21 (3 ULg) Anti-thymocyte globulin as graft-versus-host disease prevention in the setting of allogeneic peripheral blood stem cell transplantation: a review from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation.Baron, Frédéric ; Mohty, Mohamad; Blaise, Didier et alin Haematologica (2017)Allogeneic hematopoietic stem cell transplantation is increasingly used as treatment for patients with life threatening blood diseases. Their curative potential is largely based on immune-mediated graft ... [more ▼]Allogeneic hematopoietic stem cell transplantation is increasingly used as treatment for patients with life threatening blood diseases. Their curative potential is largely based on immune-mediated graft-versus-leukemia effects caused by donor T cells contained in the graft. Unfortunately, donor T cells are also the cause of graft-versus-host disease. The vast majority of HLA-matched allogeneic hematopoietic stem cell transplantations are nowadays carried out with peripheral blood stem cells (PBSC) as stem cell source. In comparison with bone marrows, PBSC contain more hematopoietic stem/progenitor cells but also one log more T cells. Consequently, the use of PBSC instead of bone marrow has been associated with faster hematological recovery and a lower risk of relapse in patients with advanced disease, but also with a higher incidence of chronic graft-versus-host disease. These observations have been the basis for several studies aimed at assessing the impact of immunoregulation with anti-thymocyte globulin (ATG) on transplantation outcomes in patients given HLA-matched PBSC from related or unrelated donors. After a brief introduction on ATG, this article reviews recent studies assessing the impact ATG on transplantation outcomes in patients given PBSC from HLA-matched related or unrelated donors as well as in recipients of grafts from HLA-haploidentical donors. [less ▲]Detailed reference viewed: 15 (3 ULg) Low-dose clofarabine in combination with a standard remission induction in patients aged 18-60 years with previously untreated intermediate and bad-risk acute myeloid leukemia or high-risk myelodysplastic syndrome: Combined phase I/II results of the EORTC/GIMEMA AML-14A trialSelleslag, Dominik; Suciu, Stefan; Meloni, Giovanna et alin Haematologica (2017)Detailed reference viewed: 18 (2 ULg) Dermatophytes and Dermatophytoses: A Thematic Overview of State of the Art, and the Directions for Future Research and DevelopmentsBouchara, JP; Mignon, Bernard ; Chaturvedi, Vin Mycopathologia (2017), 182(1), 1-4Detailed reference viewed: 13 (2 ULg) Drought, conflict and children’s undernutrition in Ethiopia 2000–2013: a meta-analysisDelbiso, Tefera Darge; Rodriguez-Llanes, Jose Manuel; Donneau, Anne-Françoise et alin Bulletin of the World Health Organization (2017), 95Detailed reference viewed: 26 (3 ULg) Reconstructing Cenozoic vegetation from proxy data and models – A NECLIME synthesis (Editorial)François, Louis ; Bruch, A. A.; Utescher, T. et alin Palaeogeography, Palaeoclimatology, Palaeoecology (2017), 467[No abstract available] Don't judge a fish by its fins: species delineation of Congolese Labeo (Cyprinidae)Van Steenberge, Maarten; Gajdzik, Laura ; Chilala, Alex et alin Zoologica Scripta (2016)Conspicuous characters are often useful in species identification. Yet, identification and delineation are two different processes, and such characters do not necessarily provide the best basis on which ... [more ▼]Conspicuous characters are often useful in species identification. Yet, identification and delineation are two different processes, and such characters do not necessarily provide the best basis on which species can be delineated. This is illustrated by the case of the Labeo with papillary lips from the Congo basin. Traditionally, species delineation in this group was based on a conspicuous trait: the shape of the dorsal fin, which shows a profound degree of differentiation. Morphometric analyses were performed on 185 specimens both with and without measurements taken on this fin. The groups obtained using these two approaches were compared with those obtained through DNA barcoding. For this, 24 sequences of the standard barcoding COI gene were obtained. Species delineations based on morphological and molecular results were in agreement when the shape of the dorsal fin was ignored. This suggested that of the five nominal species known from the Congo basin, L. altivelis, L. rosae, L. lineatus, L. weeksii and L. maleboensis, only the former three remain valid. Consequently, L. weeksii was synonymised with L. altivelis and L. maleboensis with L. lineatus. The sole Congo basin endemic is L. lineatus as L. altivelis and L. rosae also occur in more southern basins. The use of the shape of the dorsal fin in morphological studies has previously led to overestimates of species diversity in this group. This is due to the fact that L. altivelis shows a remarkable amount of geographical variation for this trait. The large amount of intra- and interspecific variation in this character was caused by differential allometric growth in different parts of the dorsal fin. [less ▲] Comprehension of an organosolv process for lignin extraction on Festuca arundinacea and monitoring of the cellulose degradationSchmetz, Quentin ; Maniet, Guillaume ; Jacquet, Nicolas et alin Industrial Crops and Products (2016), 94It is commonly accepted that the current society needs to partially substitute fossil resources by renewable ones. Among many solutions, one approach consists in the development of biorefinery involving ... [more ▼]It is commonly accepted that the current society needs to partially substitute fossil resources by renewable ones. Among many solutions, one approach consists in the development of biorefinery involving lignocellulosic biomass to produce bio-based materials and fuels. This study focuses on the comprehension of an organosolv treatment designed to break the complex lignocellulosic structure for high purity lignin extraction from tall fescue (Festuca arundinacea Schreb.). This grass benefits from an increasing interest in Western Europe and has been suggested as feedstock for biorefinery. However, its use as material for high purity lignin production has not been determined yet. Ethanol/water, 92/8% [v/v] with H2SO4 0.32 M was investigated at pilot scale under conventional heating (5 °C min−1 during 30 min and stabilized at 148 °C for 5 min). Precipitated lignin were analyzed as well as the composition of side-stream products (recovered cellulosic pulp and the aqueous hydrolysate). Lignin has been recovered at a purity level of 90% with a yield of 60%. The main contaminants were nitrogen containing compounds and degraded hemicelluloses. 2D-HSQC NMR (Two Dimension-Heteronuclear Single Quantum Correlation Nuclear Magnetic Resonance) revealed a co-extraction of ferulates and coumarates function as well as arabinoxylan. Cellulose was recovered at 53% purity with 60% yield. The conditions appear to be too harsh for tall fescue and led to significant amount of cellulose degradation. A process using a lower alcohol concentration will be developed to provide better yields of both cellulose and lignin. [less ▲]Detailed reference viewed: 66 (16 ULg) Continuous Production of Itraconazole-based Solid Dispersions by Hot Melt Extrusion: Preformulation, Optimization and Design Space Determination.Thiry, Justine ; Lebrun, Pierre; Vinassa, Chloé et alin International Journal of Pharmaceutics (2016), 515(1-2), 114-124Detailed reference viewed: 46 (9 ULg) Interpellation du genre et sujets mélancoliques. Butler lectrice d’AlthusserBorotto, Jessica in Cahiers du GRM (2016), 8Cet article propose d’explorer la manière dont Judith Butler remobilise la thèse althussérienne de l’interpellation dans La Vie psychique du pouvoir . Nous essaierons de saisir les éléments qui nous ... [more ▼]Cet article propose d’explorer la manière dont Judith Butler remobilise la thèse althussérienne de l’interpellation dans La Vie psychique du pouvoir . Nous essaierons de saisir les éléments qui nous paraissent enrichir la problématique althussérienne, suggérant que la compréhension de la dimension psychique du pouvoir qui ressort de sa lecture permet de complexifier la relation du sujet au pouvoir. Afin de tisser des liens précis entre l’interpellation chez Althusser et la subjectivation chez Butler, nous examinerons d’abord le rôle que Nietzsche et Foucault recouvrent dans la formulation de la théorie de la subjectivation chez Butler. Ensuite, il s’agit de comprendre en quoi la matérialité et l’ambiguïté des mécanismes de subjectivation, qui déjà caractérisent l’interpellation althussérienne, deviennent chez Butler les sources d’une relation critique aux conditions d’émergence du sujet. Enfin nous préciserons comment elle mobilise de telles sources pour élaborer cette figure de la psychanalyse qu’est la mélancolie et pour décrire sa transformation en deuil. [less ▲]Detailed reference viewed: 18 (1 ULg) Is Competence a Holy Grail for Teaching? Reflections on Nursing EducationDancot, Jacinthe in Nursing & Care Open Access Journal (2016), 1(4), 00021The competence-based approach is largely widespread in the nursing schools and is viewed as a golden standard for professional teaching. But the practical use of the concept is varying among institutions ... [more ▼]The competence-based approach is largely widespread in the nursing schools and is viewed as a golden standard for professional teaching. But the practical use of the concept is varying among institutions and even teachers. The goal of this narrative review is to clarify the conception of competence and its use in the fields of education and nursing. Regarding education, Gonczi, Tardif, Jonnaert and Beckers are the key authors referred to. A first apparent consensus over the holistic nature of the competence quickly gives place to the observation of important nuances in conceptions. Similarly, in the field of nursing, Benner is first discussed, and recent literature reviews and concept analyses are taken into account: similar nuances are detected, as well as difficulties in the practical implementation of the concept. Considering the lack of consensus and the paradigmaticalincoherences detected among the sources consulted for this review, we question the use of competence as single point of view for teaching and assessing, and we propose other avenues to be explored in order to recognize emergent professionality. [less ▲]Detailed reference viewed: 308 (2 ULg) Learning from Incidents and Incident Reporting: Safety Governance at a Belgian Nuclear Research CenterRossignol, Nicolas ; Van Oudheusden, Michiel in Science, Technology & Human Values (2016), Online FirstThis article examines how incidents are governed in a Belgian Nuclear Research Center by way of an incident reporting system named REX. Drawing on a documentary analysis of incident reports, interviews ... [more ▼]This article examines how incidents are governed in a Belgian Nuclear Research Center by way of an incident reporting system named REX. Drawing on a documentary analysis of incident reports, interviews and focus groups with personnel, it illustrates how REX enacts a safety governmentality centered on identifying incident causes and culprits. As this governmentality mode obscures the epistemic and political character of incidents, it closes down important opportunities for collective learning about safety and safety governance. It is argued that joint reflection about incidents and resistances towards incident reporting serve as fruitful starting points for a more reflexive safety governance that makes explicit how decisions are made in high-risk contexts. Social scientists can enhance governance of this kind by pointing to different perceptions and evaluations of incidents and by insisting that contending interpretations are confronted and accounted for. [less ▲]Detailed reference viewed: 14 (3 ULg) Screening transplant donors for HTLV-1 and -2Gallo, Robert; Willems, Luc ; Hasegawa, 4 Hideki et alin Blood (2016), 128(26), Detailed reference viewed: 9 (1 ULg) Neuromuscular blockade as part of an anaesthetic protocol for cataract surgery in an alpacaTutunaru, Alexandru-Cosmin ; Storms, Goedele ; Monclin, Sébastien et alin Journal of Camelid Science (2016), 9A six-month-old alpaca was presented to the veterinary teaching hospital of the University of Liège (Belgium) with a bilateral cataract. A decision was made to perform bilateral cataract surgery after an ... [more ▼]A six-month-old alpaca was presented to the veterinary teaching hospital of the University of Liège (Belgium) with a bilateral cataract. A decision was made to perform bilateral cataract surgery after an ocular ultrasound and electroretinogram were performed to assess the posterior segment and retinal function, respectively. As a premedication, the alpaca received xylazine, butorphanol and midazolam intramuscularly. Anaesthesia was induced subsequently with ketamine and midazolam intravenously and maintained with isoflurane on oxygen/air mixture. The alpaca was mechanically ventilated during surgery. Neuromuscular blockade was induced and maintained with cis-atracurium intravenously. The dose of cis-atracurium was permanently adapted using a peripheral nerve stimulator. This case report brings new knowledge regarding the use and dosage of cis-atracurium in alpacas. [less ▲]Detailed reference viewed: 16 (4 ULg) EditorialBorotto, Jessica ; Petteni, Oriane ; Wustefeld, Sophie et alin Cahiers du GRM (2016), 10Detailed reference viewed: 16 (6 ULg) Effect of the Extraction Technique, Heating Time and Cryogenic Grinding (N2 at -196°C) on the Composition of Cumin Seeds Volatile OilMékaoui, R; Benkaci-Ali, Farid; Scholl, Georges et alin Journal of Essential Oil-Bearing Plants [=JEOBP] (2016), 19(8), 1903-1919Two techniques of extraction of essential oils (Steam distillation assisted by microwave (SDAM) and hydrodistillation assisted by microwave (HDAM)) are respectively advanced steam distillation (SD) and ... [more ▼]Two techniques of extraction of essential oils (Steam distillation assisted by microwave (SDAM) and hydrodistillation assisted by microwave (HDAM)) are respectively advanced steam distillation (SD) and hydrodistillation techniques (HD), in which a microwave oven is used in the extraction process. They are considered as accelerated techniques extraction performed at atmospheric pressure. The cryogrinding (CG) showed a difference on the yields and aromatic profile comparing to the sample grinding. Isolation and concentration of volatile compounds are performed by a single stage for the extraction of volatile oil from Algerian (Sahara) Cuminum cyminum seeds (CCS). The chemical composition of the essential oil of this plant as a function of extraction time was also studied. The major components and family classes showed a significant variation with the extraction time. Gas chromatography (GC), GCxGC-mass spectrometry (GCxGC-MS)] were utilised for qualitative and quantitative analysis of essential oils extracted by these two methods. The major compounds are cumin aldehyde (HDAM-CG: 20.50-53.35 %, SDAM-CG: 21.68 66.6 %), p-cymene (HDAM-CG: 14.1-37.54 %, SDAM-CG: 6.06-20.18 %), β-pinene (HDAM-CG: 4.53-14.74 %, SDAM-CG: 4.3-32.65 %) and γ-terpinene (HDAM-CG: 1.26-14.70 %, SDAM-CG: 5.13-18.23 %). [less ▲]Detailed reference viewed: 13 (1 ULg) SU(3) flavor symmetry breaking in large $N_c$ excited baryonsStancu, Floarea in Physical Review. D : Particles and Fields (2016), 94The $1/N_c$ expansion method for studying the mass spectrum of excited baryons is shortly reviewed together with applications to mixed symmetric states. The $[{\bf 70, \ell^+}]$ multiplet, belonging to ... [more ▼]The $1/N_c$ expansion method for studying the mass spectrum of excited baryons is shortly reviewed together with applications to mixed symmetric states. The $[{\bf 70, \ell^+}]$ multiplet, belonging to the $N$ = 2 band, is reanalyzed, with emphasis on hyperons and the SU(3) symmetry breaking operators entering the mass formula to first order. An important result is that the hierarchy of masses as a function of strangeness is correctly reproduced for all multiplets. Predictions for unknown excited hyperons to SU(6) $\times$ O(3) multiplets are made. [less ▲]Detailed reference viewed: 10 (2 ULg) Agricultural economics and development with implications to the Central HighlandsLebailly, Philippe Scientific conference (2016, December 23)Detailed reference viewed: 14 (2 ULg) Présentation du livre "Des partenariats publics privés pour l'insertion des demandeurs d'emploi: une question de confiance?"Remy, Céline Conference given outside the academic context (2016)Detailed reference viewed: 13 (0 ULg)