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See detailThinking out of the box - New approaches to controlling GVHD
Baron, Frédéric ULg; Humblet-Baron, Stéphanie; Ehx, Grégory ULg et al

in Current Hematologic Malignancy Reports (in press)

Graft-versus-host disease (GVHD) remains a major limitation of allogeneic hematopoietic cell transplantation (allo-HCT). Despite major advances in the understanding of GVHD pathogenesis, standard GVHD ... [more ▼]

Graft-versus-host disease (GVHD) remains a major limitation of allogeneic hematopoietic cell transplantation (allo-HCT). Despite major advances in the understanding of GVHD pathogenesis, standard GVHD prophylaxis regimens continue to bebased on the combination of a calcineurin inhibitor with an antimetabolite, while first line treatmentsstill relies on high-dose corticosteroids. Further, no second line treatment has emerged thus far in acute or chronic GVHD patients who failed on corticosteroids. After briefly reviewing current standards of GVHD prevention and treatment, this article will discuss recent approaches that might change GVHD prophylaxis / treatment in the next decades, with a special focus on recently developed immunoregulatory strategies based on infusion of mesenchymal stromal or regulatory T-cells, or on injection of lowdose interleukin-2. [less ▲]

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See detailCharge Migration in the Bifunctional PENNA Cation Induced and Probed by Ultrafast Ionization: A Dynamical Study. Submitted
Mignolet, Benoît ULg; Levine, R. D.; Remacle, Françoise ULg

in Journal of Physics : B Atomic Molecular & Optical Physics (in press)

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See detailBoucle et répétition : musique, littérature, arts visuels
Belloi, Livio ULg; Delville, Michel ULg; Levaux, Christophe ULg et al

Book published by Presses Universitaires de Liège (in press)

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See detailClassification of positron emission tomography images using multiple kernel learning
Segovia-Román, Fermín ULg; Bastin, Christine ULg; Salmon, Eric ULg et al

in Proceeding of 3rd NIPS 2013 Workshop on Machine Learning and Interpretation in NeuroImaging (in press)

Over the last years, several approaches to analyze nuclear medicine imaging using computer systems have been proposed with the aim of assisting the diagnosis of neurodegenerative disorders. Probably one ... [more ▼]

Over the last years, several approaches to analyze nuclear medicine imaging using computer systems have been proposed with the aim of assisting the diagnosis of neurodegenerative disorders. Probably one of the most complex challenges facing these approaches is to deal with the huge amount of data provided by brain images. In this work, we propose an original approach based on multiple kernel learning. First the images were parcellated (according to the structure of the brain) by means of the automatic anatomical labeling atlas. Then, the importance of each region for the assisted diagnosis was estimated using a classifi- cation procedure. Finally, all the regions were combined in a multiple kernel method in which one kernel per region was computed and all the kernels were weighted according to the importance of the region they represented. For testing purposes, a database with 46 PET images from stable mild cognitive impairment subjects and early Alzheimer’s disease converter patients was used. An accuracy rate of 73.91% was achieved when differentiating between both groups. [less ▲]

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See detailApport de la musculation en sport collectifamateur : exemple du handball féminin
Jidovtseff, Boris ULg; Frère, Pauline; Theunissen, Catherine ULg

in Science & Sports (in press)

Introduction. — The aim of the study was to verify, in a non-professional handball female, if theintroduction of two short workouts per week during all season has a positive impact on muscularperformance ... [more ▼]

Introduction. — The aim of the study was to verify, in a non-professional handball female, if theintroduction of two short workouts per week during all season has a positive impact on muscularperformance.Methods. — Eighteen female playing handball at the top Belgian level were monitored duringthe complete season. Ten of these girls (‘‘Muscu’’ group) achieved, in addition to their usualtraining, two short (30 minutes) strength training sessions weekly. The other (‘‘Control’’ group)followed the usual training, without any strength training session. A battery of tests (leg power,arm power, vertical jump, sprint, throwing, flexibility) has been set up to four times during theseason to follow up muscular performance.Results. — According to the literature, the ‘‘Control’’ group showed any change in performanceduring the year. By contrast, ‘‘Muscu group results demonstrated that the short strength trai-ning program was efficient, with significant improvements in leg power (P < 0.005) and sprint(P < 0.05) tests. Increase in vertical jump was very close to the level of significance (P = 0.06).Arms power did not improve but appeared to be superior in the ‘‘Muscu’’ group in comparisonwith ‘‘Control’’ at the end of the season, which was not the case at the beginning.© 2013 Elsevier Masson SAS. All rights reserved. [less ▲]

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See detailÉtude anatomoradiologique d’un crâne déformé d’Ancón (Pérou)
Ricciardetto, Antonio ULg; Boman, Françoise; Duchat, Florent et al

in Charlier, Philippe (Ed.) Actes du Ve Colloque international de Pathographie (in press)

Matériels et méthodes : l’étude porte sur un crâne déformé provenant d’Ancón au Pérou, inventorié au Muséum National d’Histoire Naturelle (MNHN) de Paris en 1889. L’étude est géographique, historique ... [more ▼]

Matériels et méthodes : l’étude porte sur un crâne déformé provenant d’Ancón au Pérou, inventorié au Muséum National d’Histoire Naturelle (MNHN) de Paris en 1889. L’étude est géographique, historique, macroscopique et tomodensitométrique. Résultats : situé sur la côte à 40 km au nord de Lima, la capitale du Pérou, le site d’Ancón est un site archéologique de la période lithique, et un lieu de sépulture depuis l’époque Chavín (1250 à 250 av. J.-Chr.). Dès l’époque Chavín, les peuples du Pérou ancien construisaient des centres cérémoniels dirigés par une élite théocratique, et déformaient le crâne des enfants dès les premiers jours de la vie, à l’aide de moyens de pression variés. La déformation du crâne d’Ancón est une déformation antéro-postérieure oblique, brachycéphale, bilobée et asymétrique, sans trépanation ni déformation dentaire associée. C’est une variante bilobée du type Huaura de déformation crânienne, qui est associé aux régions de Chancay-Ancón et Lima. L’étude tomodensitométrique des variations d’épaisseur de la voûte, avec amincissement en regard des zones de pression, a montré que la déformation était intentionnelle, et caractérisée par une pression fronto-pariéto-temporale bilatérale surtout antérieure et dégressive d’avant en arrière, associée à une pression frontale, occipitale, et sagittale médiane. En l’absence de contexte et de datation, l’ancienneté du crâne étudié ne peut pas être précisée au long d’une période de presque trois millénaires, jusqu’à la domination Inca et l’arrivée des Espagnols (1532). Le crâne pourrait appartenir à l’une ou l’autre des cultures successives du site d’Ancón : Chavín, Baňos de Boza o Miramar, Lima, Wari, et Chancay (1200 à 1470), dont les céramiques représentent la déformation bilobée. Le crâne est probablement celui d’une femme âgée de plus de 45 ans à son décès, de statut social élevé, faisant partie de l’élite magico-religieuse, politique et économique dirigeante. L’étude de l’endocrâne a permis d’observer la déformation des veines superficielles et des lobes du cerveau. Il existe des signes de parodonpathie chronique à un stade avancé. Un abcès d’origine dentaire pourrait avoir été la cause du décès. Conclusions et perspectives : en ce qui concerne la pratique des déformations crâniennes, la région d’Ancón-Chancay et de Lima paraît être remarquable à trois égards : par le grand nombre de crânes déformés, par le grand nombre de crânes bilobés, et par la proportion importante de femmes, dont on peut supposer qu’elles étaient nées de familles nobles, et destinées dès l’enfance à faire partie de l’élite théocratique. La reconstitution 3D de l’épaisseur de la voûte crânienne a permis pour la première fois à notre connaissance de caractériser ce type de déformation, et pourrait permettre de reconstituer l’appareil déformateur. Seule la reprise des exhumations programmées sur le site d’Ancón, dans le cadre d’un projet prospectif pluridisciplinaire, pourrait permettre de mieux préciser la proportion d’individus à crâne déformé, la proportion des crânes bilobés, et le sex ratio, dans chaque contexte historique et socio-culturel de ce type de déformation crânienne intentionnelle ; et, peut-être, de retrouver in situ l’appareil déformateur correspondant. [less ▲]

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See detailSynthèse bibliographique sur la mobilité des éléments traces dans les sols et l’utilisation de la stabilisation physico-chimique comme technique de gestion in situ des sites contaminés
Liénard, Amandine ULg; Colinet, Gilles ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (in press)

Industrial activities have deeply impacted the quality of biophysical environment at places. This review focuses on consequences of soil contaminations by metallic trace elements: what conditions the ... [more ▼]

Industrial activities have deeply impacted the quality of biophysical environment at places. This review focuses on consequences of soil contaminations by metallic trace elements: what conditions the mobility of contaminants in soils and what are the remediation practices based upon physico-chemical stabilization? This technique is an in situ remediation which aims at limiting the dispersion of metals in the environment by use of soil conditioners and amendments in contaminated sites. First of all, we reviewed the concepts of mobility of trace elements and their indicators. Then, we compiled the different kinds of amendments applied to stabilize contaminants in soils and the processes involved. [less ▲]

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See detailÉVOLUTION DE LA TENEUR EN EAU LE LONG D’UNE TOPOSEQUENCE FORESTIERE ARGILO-LIMONEUSE
Deraedt, Deborah ULg; Colinet, Gilles ULg; Degré, Aurore ULg

in Milieux Poreux et Transferts Hydriques (in press)

For the hydrological modeling of forested watersheds, the understanding of the forest hydrodynamic is essential. This study focusses on the hydrology of a Belgian forested plot with high stoniness and ... [more ▼]

For the hydrological modeling of forested watersheds, the understanding of the forest hydrodynamic is essential. This study focusses on the hydrology of a Belgian forested plot with high stoniness and steep slope. The soil water content is monitored at several positions on the toposequence and at different depth. During rain events, peak in soil water content are observed in different depth depending on the position along the toposequence. [less ▲]

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See detailIntroduction
Levaux, Christophe ULg

in Belloi, Livio; Delville, Michel; Levaux, Christophe (Eds.) et al Boucle et répétition : musique, littérature, arts visuels (in press)

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See detailOn the asymptotic standard error of a class of robust estimators of ability in dichotomous item response models
Magis, David ULg

in British Journal of Mathematical & Statistical Psychology (in press)

In item response theory, the classical estimators of ability are highly sensitive to response disturbances and can return strongly biased estimates of the true underlying ability level. Robust methods ... [more ▼]

In item response theory, the classical estimators of ability are highly sensitive to response disturbances and can return strongly biased estimates of the true underlying ability level. Robust methods were introduced to lessen the impact of such aberrant responses onto the estimation process. The computation of asymptotic (i.e., large sample) standard errors (ASE) for these robust estimators, however, has not been fully considered yet. This paper focuses on a broad class of robust ability estimators, defined by an appropriate selection of the weight function and the residual measure, for which the ASE is derived from the theory of estimating equations. The maximum likelihood (ML) and the robust estimators, together with their estimated ASE, are then compared through a simulation study. It is concluded that both the estimators and their ASE perform similarly in absence of response disturbances, while the robust estimator and its estimated ASE are less biased and outperform their ML counterparts in presence of response disturbances with large impact on the item response process. [less ▲]

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See detailA Schur Complement Method for DAE Systems in Power System Dynamic Simulations
Aristidou, Petros ULg; Fabozzi, Davide; Van Cutsem, Thierry ULg

in Lecture Notes in Computational Science and Engineering (in press)

This paper proposes a Schur complement-based Domain Decomposition Method to accelerate the time-domain simulation of large, non-linear and stiff Differential and Algebraic Equation systems stemming from ... [more ▼]

This paper proposes a Schur complement-based Domain Decomposition Method to accelerate the time-domain simulation of large, non-linear and stiff Differential and Algebraic Equation systems stemming from power system dynamic studies. The proposed algorithm employs a star-shaped decomposition scheme and exploits the locality and sparsity of the system. The simulation is accelerated by the use of quasi-Newton schemes and parallel programming techniques. The proposed algorithm is implemented using the shared-memory parallel programming model and tested on a large-scale, realistic power system model showing significant speedup. [less ▲]

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See detailA Super-Jupiter orbiting a late-type star: A refined analysis of microlensing event OGLE-2012-BLG-0406
Tsapras, Y.; Choi, J.-Y.; Street, R. A. et al

in Astrophysical Journal (in press)

We present a detailed analysis of survey and follow-up observations of microlensing event OGLE-2012-BLG-0406 based on data obtained from 10 different observatories. Intensive coverage of the lightcurve ... [more ▼]

We present a detailed analysis of survey and follow-up observations of microlensing event OGLE-2012-BLG-0406 based on data obtained from 10 different observatories. Intensive coverage of the lightcurve, especially the perturbation part, allowed us to accurately measure the parallax effect and lens orbital motion. Combining our measurement of the lens parallax with the angular Einstein radius determined from finite-source effects, we estimate the physical parameters of the lens system. We find that the event was caused by a $2.73\pm 0.43\ M_{\rm J}$ planet orbiting a $0.44\pm 0.07\ M_{\odot}$ early M-type star. The distance to the lens is $4.97\pm 0.29$\ kpc and the projected separation between the host star and its planet at the time of the event is $3.45\pm 0.26$ AU. We find that the additional coverage provided by follow-up observations, especially during the planetary perturbation, leads to a more accurate determination of the physical parameters of the lens. [less ▲]

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See detailDe Jacques Antoine aux Eperonniers : l'édition littéraire en Belgique au passé et au présent (seconde partie)
Durand, Pascal ULg; Habrand, Tanguy ULg

in Textyles : Revue des Lettres Belges de Langue Française (in press)

Second volet d'un article en deux parties portant sur l'édition littéraire contemporaine en Belgique, autour de deux maisons importantes : les éditions Jacques Antoine et les éditions des Eperonniers. La ... [more ▼]

Second volet d'un article en deux parties portant sur l'édition littéraire contemporaine en Belgique, autour de deux maisons importantes : les éditions Jacques Antoine et les éditions des Eperonniers. La seconde partie de cette étude porte plus précisément sur la transition d'une maison à l'autre et sur la politique de la création contemporaine suivie par Lysiane d'Hayere aux Eperonniers. [less ▲]

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See detailIl design come strumento politico e ideologico, tra Firenze e Torino (1965-1975)
Prina, Daniela ULg

in Allegoria (in press), 68(2),

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See detailIntroduction à l'ouvrage rétrospectif "Jean-Pierre Ransonnet"
Bawin, Julie ULg

in Jean-Pierre Ransonnet (in press)

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See detailMémoire implicite: Théorie, évaluation, et implications cliniques
Adam, Stéphane ULg

in Van der Linden, Martial; Seron, Xavier (Eds.) Traité de neuropsychologie clinique (2ème édition) (in press)

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See detailRecent advances in the biomonitoring of trace elements using P. oceanica (L.) Delile
Gobert, Sylvie ULg; Richir, Jonathan ULg

in CIESM Congress Proceedings n°40 (in press)

One of the most studied bioindicator in the Mediterranean is the seagrass Posidonia oceanica. Trace element (TE) monitoring surveys using that species have however mostly focussed on a few elements (e.g ... [more ▼]

One of the most studied bioindicator in the Mediterranean is the seagrass Posidonia oceanica. Trace element (TE) monitoring surveys using that species have however mostly focussed on a few elements (e.g. Pb, Cd), while numerous others, efficiently bioconcentrated by the plant and potentially toxic, have been barely or not studied (e.g. Ag, V, Bi). Furthermore, although P. oceanica bioaccumulation behaviour relies on synergistic effects between the sampling environment and its ecophysiology, this aspect has been mostly underestimated until now. This study presents recent advances in the biomonitoring of TEs using P. oceanica and insists on the necessity of developing consensual monitoring protocols in order to improve its use as bioindicator. [less ▲]

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